TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5ccbf43bc0f27
Sample: 5ccbf43bc0f27

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Summary
ID: 5ccbf43bc0f27
Date: Fri May 3 08:59:30 2019
Strain: root
Drug-resistance: Drug-resistant

Drug1ResistanceSupporting Mutations (frequency)
IsoniazidRkasA p.Arg121Lys (1.00)
Rifampicin
EthambutolRembB p.Ala356Val (1.00), embB p.Ala388Gly (1.00)
Pyrazinamide
Streptomycin
Ethionamide
FluoroquinolonesRgyrB p.Thr500Asn (1.00)
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5332c.93C>T1.000
gyrB5341c.102T>C1.000
gyrB5347c.108G>C1.000
gyrB5356c.117G>A1.000
gyrB5363c.124T>C1.000
gyrB5371c.132T>C1.000
gyrB5374c.135C>G1.000
gyrB5377c.138T>C1.000
gyrB5386c.147G>T1.000
gyrB5410c.171G>T1.000
gyrB5803c.564A>G1.000
gyrB5812c.573C>A1.000
gyrB5815c.576C>A1.000
gyrB5824c.585A>G1.000
gyrB5848c.609G>T1.000
gyrB5858p.Asn207Asp1.000
gyrB5873c.634A>C1.000
gyrB6085c.846C>A1.000
gyrB6091c.852G>A1.000
gyrB6097c.858G>A1.000
gyrB6100c.861G>C1.000
gyrB6109c.870G>T1.000
gyrB6110p.Met291Leu1.000
gyrB6123p.Ala295Gly1.000
gyrB6127c.888G>T1.000
gyrB6130c.891T>C1.000
gyrB6163c.924C>T1.000
gyrB6170p.His311Ala1.000
gyrB6202c.963C>G1.000
gyrB6203c.964A>T1.000
gyrB6214c.975G>C1.000
gyrB6215c.976T>A1.000
gyrB6223c.984G>C1.000
gyrB6238c.999G>A1.000
gyrB6242p.Arg335Lys1.000
gyrB6250c.1011A>G1.000
gyrB6253c.1014G>C1.000
gyrB6265c.1026C>T1.000
gyrB6274c.1035C>G1.000
gyrB6286c.1047T>C1.000
gyrB6292c.1053G>C0.981
gyrB6295c.1056A>G1.000
gyrB6299c.1060C>T1.000
gyrB6307c.1068T>G1.000
gyrB6310c.1071G>C1.000
gyrB6361c.1122G>A0.985
gyrB6362c.1123T>C1.000
gyrB6382c.1143A>G1.000
gyrB6388c.1149T>C1.000
gyrB6610c.1371C>G1.000
gyrB6613c.1374A>G1.000
gyrB6616c.1377A>G1.000
gyrB6622c.1383C>T1.000
gyrB6625c.1386G>A1.000
gyrB6634c.1395T>C1.000
gyrB6637c.1398T>G1.000
gyrB6640c.1401A>C1.000
gyrB6643c.1404A>G1.000
gyrB6649c.1410T>C1.000
gyrB6655c.1416T>C1.000
gyrB6673c.1434A>C1.000
gyrB6676c.1437T>G1.000
gyrB6700c.1461T>C1.000
gyrB6703c.1464G>C1.000
gyrB6709c.1470A>G1.000
gyrB6712c.1473G>C1.000
gyrB6724c.1485G>C1.000
gyrB6730c.1491A>G1.000
gyrB6742c.1503A>G1.000
gyrB6745c.1506T>C1.000
gyrB6760c.1521G>C1.000
gyrB6763c.1524G>T1.000
gyrB6775c.1536G>T1.000
gyrB6778c.1539C>T1.000
gyrB6793c.1554T>C1.000
gyrB6797p.Gly520Ser1.000
gyrB6811c.1572C>T1.000
gyrB6826c.1587G>A1.000
gyrB6844c.1605T>C1.000
gyrB6853c.1614A>G1.000
gyrB6856c.1617T>C1.000
gyrB6859c.1620T>C1.000
gyrB6889c.1650G>T1.000
gyrB6904c.1665C>G1.000
gyrB6905p.Ile556Val1.000
gyrB6911p.Asn558His1.000
gyrB6919c.1680T>C1.000
gyrB6925c.1686T>C1.000
gyrB6931c.1692A>G1.000
gyrB6934c.1695A>G1.000
gyrB6949c.1710A>G1.000
gyrB6966p.Ser576Asn1.000
gyrB6971p.Pro578Ala1.000
gyrB6982c.1743A>C1.000
gyrB6997c.1758G>A1.000
gyrB7000c.1761C>T1.000
gyrB7012c.1773G>C1.000
gyrB7015c.1776G>A1.000
gyrB7018c.1779G>C1.000
gyrB7023p.Leu595Pro1.000
gyrB7027c.1789 1790insCC1.000
gyrA7313c.12G>C1.000
gyrA7317c.16T>C1.000
gyrA7322c.21G>A1.000
gyrA7325c.24T>A1.000
gyrA7335p.Leu12Val1.000
gyrA7355c.54T>C1.000
gyrA7358c.57C>T1.000
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T1.000
gyrA7394c.93T>C1.000
gyrA7397c.96G>C1.000
gyrA7412c.111C>G1.000
gyrA7421c.120G>A1.000
gyrA7427c.126G>C1.000
gyrA7433c.132G>A1.000
gyrA7442c.141G>T1.000
gyrA7451c.150C>G1.000
gyrA7457c.156T>C1.000
gyrA7463c.162G>C1.000
gyrA7472c.171T>C1.000
gyrA7475c.174A>G1.000
gyrA7480p.Phe60Tyr1.000
gyrA7484c.183T>C1.000
gyrA7490c.189C>G1.000
gyrA7496c.195C>T1.000
gyrA7499c.198G>C1.000
gyrA7514c.213C>G1.000
gyrA7517c.216G>A1.000
gyrA7520c.219G>C1.000
gyrA7523c.222C>A0.982
gyrA7541c.240C>G1.000
gyrA7571c.270G>C1.000
gyrA7585p.Ser95Thr1.000
gyrA7592c.291G>C1.000
gyrA7595c.294C>G1.000
gyrA7607c.306C>G1.000
gyrA7619c.318C>T1.000
gyrA7631c.330G>C1.000
gyrA7640c.339G>A1.000
gyrA7652c.351C>T1.000
gyrA7658c.357A>G0.984
gyrA7664c.363T>C1.000
gyrA7670c.369A>C1.000
gyrA7671p.Pro124Ala1.000
gyrA7676c.375G>C1.000
gyrA7679c.378G>C1.000
gyrA7683c.382A>C1.000
gyrA7694c.393A>G1.000
gyrA7706c.405C>G1.000
gyrA7710c.409T>C1.000
gyrA7715c.414G>C0.982
gyrA7725c.424C>T1.000
gyrA7728c.427A>C1.000
gyrA7745c.444G>A1.000
gyrA7758p.Ile153Val1.000
gyrA7763c.462T>G1.000
gyrA7797c.496C>T1.000
gyrA7802c.501C>G1.000
gyrA7805c.504C>T1.000
gyrA7814c.513C>G1.000
gyrA7832c.531G>C1.000
gyrA7835c.534A>C1.000
gyrA7841c.540C>T1.000
gyrA7859c.558A>G0.941
gyrA7865c.564T>C1.000
gyrA7868c.567C>T1.000
gyrA7886c.585T>C1.000
gyrA7889c.588G>A1.000
gyrA7892c.591G>C1.000
gyrA7898p.Asp199Glu1.000
gyrA7958c.657C>G1.000
gyrA7963p.Gly221Glu1.000
gyrA7970c.669T>C1.000
gyrA7973c.672A>G1.000
gyrA7988c.687G>C1.000
gyrA7992p.Ala231Ser1.000
gyrA8009c.708A>C1.000
gyrA8012c.711C>G1.000
gyrA8020p.Thr240Ile1.000
gyrA8022p.Ala241Asn1.000
gyrA8027c.726T>C1.000
gyrA8034p.Lys245Arg1.000
gyrA8039c.738T>C1.000
gyrA8042c.741C>G1.000
gyrA8045c.744C>G1.000
gyrA8054c.753T>C1.000
gyrA8057c.756A>G1.000
gyrA8066c.765A>C1.000
gyrA8069c.768T>C1.000
gyrA8076p.Val259Ile1.000
gyrA8087c.786T>C1.000
gyrA8090c.789C>G1.000
gyrA8096c.795T>G1.000
gyrA8099c.798T>G1.000
gyrA8100p.Thr267Ala1.000
gyrA8103p.Ser268Leu1.000
gyrA8111c.810G>C1.000
gyrA8121c.820T>C1.000
gyrA8129c.828T>C1.000
gyrA8156c.855T>G1.000
gyrA8168c.867A>G1.000
gyrA8174c.873C>G1.000
gyrA8177c.876A>C1.000
gyrA8183c.882C>A0.952
gyrA8187c.886C>T1.000
gyrA8191p.Ala297Val1.000
gyrA8195c.894C>A1.000
gyrA8198c.897T>C1.000
gyrA8199p.Ser300Ala1.000
gyrA8207c.906T>C1.000
gyrA8210c.909G>A1.000
gyrA8217c.916T>A1.000
gyrA8225c.924T>C1.000
gyrA8228c.927G>A1.000
gyrA8231c.930C>G1.000
gyrA8234c.933T>C1.000
gyrA8237c.936A>G1.000
gyrA8247p.Ile316Val1.000
gyrA8258c.957G>A1.000
gyrA8264c.963T>C1.000
gyrA8270c.969G>C0.778
gyrA8283p.Ile328Leu0.784
gyrA8288c.987T>C1.000
gyrA8294c.993T>C1.000
gyrA8309c.1008G>A1.000
gyrA8324c.1023T>C1.000
gyrA8339c.1038A>C1.000
gyrA8340p.Ala347Ser1.000
gyrA8351c.1050C>T1.000
gyrA8366c.1065G>C1.000
gyrA8480c.1179C>T1.000
gyrA8486c.1185T>C1.000
gyrA8492c.1191G>C1.000
gyrA8498c.1197C>T1.000
gyrA8501c.1200G>C1.000
gyrA8504c.1203G>C1.000
gyrA8513c.1212C>G1.000
gyrA8516c.1215T>C1.000
gyrA8519c.1218A>C1.000
gyrA8531c.1230G>A1.000
gyrA8535p.Glu412Gln1.000
gyrA8546c.1245T>C1.000
gyrA8552c.1251C>T1.000
gyrA8561c.1260A>C1.000
gyrA8585c.1284C>T1.000
gyrA8588p.Glu429Asp1.000
gyrA8591c.1290C>T1.000
gyrA8597c.1296C>G1.000
gyrA8600c.1299G>A1.000
gyrA8603c.1302A>G1.000
gyrA8619c.1318T>C1.000
gyrA8624c.1323G>C1.000
gyrA8627c.1326C>G1.000
gyrA8633c.1332C>G1.000
gyrA8636c.1335A>G1.000
gyrA8649p.Arg450Lys1.000
gyrA8660c.1359C>T1.000
gyrA8663p.Asp454Glu1.000
gyrA8664c.1363C>T1.000
gyrA8672c.1371A>G1.000
gyrA8783c.1482G>C1.000
gyrA8786c.1485T>C1.000
gyrA8801c.1500G>C1.000
gyrA8817p.Ser506Ala1.000
gyrA8825c.1524G>A1.000
gyrA8829c.1528T>C1.000
gyrA8840c.1539C>T1.000
gyrA8849c.1548C>G1.000
gyrA8852c.1551T>C1.000
gyrA8858c.1557T>C1.000
gyrA8867c.1566A>G1.000
gyrA8870c.1569G>C1.000
gyrA8873c.1572A>C1.000
gyrA8903c.1602T>C1.000
gyrA8915c.1614A>G1.000
gyrA8924c.1623C>T0.941
gyrA8930c.1629C>T0.932
gyrA8933c.1632G>A0.931
gyrA8939c.1638T>C1.000
gyrA8942c.1641G>C1.000
gyrA8945c.1644G>C1.000
gyrA8946c.1645T>C1.000
gyrA8981c.1680G>C1.000
gyrA8990c.1689C>G1.000
gyrA8996c.1695T>C1.000
gyrA8998p.Leu566Trp1.000
gyrA9017c.1716C>G1.000
gyrA9023c.1722A>C1.000
gyrA9029c.1728T>G1.000
gyrA9032c.1731T>C1.000
gyrA9035c.1734G>A1.000
gyrA9044c.1743C>G1.000
gyrA9056c.1755C>G1.000
gyrA9062c.1761C>G1.000
gyrA9064p.Ser588Leu1.000
gyrA9068c.1767G>C1.000
gyrA9071c.1770G>C1.000
gyrA9074c.1773G>A1.000
gyrA9080c.1779G>C1.000
gyrA9089c.1788G>C1.000
gyrA9099c.1798T>C1.000
gyrA9116c.1815G>A1.000
gyrA9119c.1818A>G1.000
gyrA9128c.1827C>T1.000
gyrA9143c.1842T>C1.000
gyrA9144p.Arg615Lys1.000
gyrA9147p.Gly616Ser1.000
gyrA9153p.Thr618Glu1.000
gyrA9161c.1860C>G1.000
gyrA9167c.1866C>T1.000
gyrA9182c.1881T>C1.000
gyrA9191c.1890G>T1.000
gyrA9197c.1896G>C1.000
gyrA9200c.1899A>G1.000
gyrA9230c.1929T>C1.000
gyrA9233c.1932C>G1.000
gyrA9236c.1935G>C1.000
gyrA9242c.1941A>C1.000
gyrA9245c.1944C>T0.979
gyrA9248c.1947G>C0.639
gyrA9252p.Val651Ile0.667
gyrA9267p.Asn656Gly1.000
gyrA9275c.1974G>A1.000
gyrA9281c.1980C>G1.000
gyrA9284c.1983T>C1.000
gyrA9296c.1995T>C1.000
gyrA9299c.1998G>C1.000
gyrA9304p.Gly668Glu1.000
gyrA9308p.Asp669Glu1.000
gyrA9323c.2022C>G1.000
gyrA9329c.2028C>G1.000
gyrA9335c.2034G>T1.000
gyrA9345c.2044A>C1.000
gyrA9365p.Glu688Asp0.795
gyrA9377c.2076A>G1.000
gyrA9383c.2082T>G1.000
gyrA9395c.2094G>C1.000
gyrA9419c.2118T>C1.000
gyrA9420p.Ile707Ala1.000
gyrA9425c.2124C>T1.000
gyrA9443c.2142G>C1.000
gyrA9449c.2148C>G1.000
gyrA9452c.2151G>C1.000
gyrA9455c.2154T>C1.000
gyrA9458p.Glu719Asp1.000
gyrA9460p.Gly720Asp1.000
gyrA9464c.2163C>T1.000
rpoB759604c.-203A>T1.000
rpoB759606c.-201T>C1.000
rpoB759814p.Asp3Val1.000
rpoB760046c.240G>C1.000
rpoB760055c.249G>T1.000
rpoB760059p.Tyr85Glu1.000
rpoB760076c.270C>T1.000
rpoB760091c.285G>C1.000
rpoB760101c.295T>C1.000
rpoB760112c.306T>C1.000
rpoB760118c.312T>G1.000
rpoB760121c.315T>G1.000
rpoB760130p.Asp108Glu1.000
rpoB760139c.333A>C1.000
rpoB760142c.336C>G1.000
rpoB760148p.Asp114Glu1.000
rpoB760155p.Lys117Arg1.000
rpoB760172c.366G>C1.000
rpoB760181c.375T>C1.000
rpoB760184c.378A>G1.000
rpoB760199c.393C>G1.000
rpoB760223c.417T>C1.000
rpoB760235c.429T>C1.000
rpoB760283c.477G>C1.000
rpoB760298c.492G>C1.000
rpoB760307c.501T>G1.000
rpoB760317c.511A>T1.000
rpoB760331c.525G>T1.000
rpoB760340c.534G>T1.000
rpoB760354p.Glu183Ala1.000
rpoB760357p.Thr184Asn1.000
rpoB760361c.555T>C1.000
rpoB760376p.Asp190Glu1.000
rpoB760389c.583A>T1.000
rpoB760394c.588C>G0.958
rpoB760407p.Ser201Gly1.000
rpoB760412c.606C>T1.000
rpoB760418c.612G>C1.000
rpoB760424c.618C>G1.000
rpoB760430c.624T>C1.000
rpoB760449p.Thr215Leu1.000
rpoB760460c.654G>T1.000
rpoB760463c.657C>T1.000
rpoB760475c.669A>G1.000
rpoB760481c.675G>C1.000
rpoB760484c.678A>G1.000
rpoB760494p.Val230Ile1.000
rpoB760521c.715A>T1.000
rpoB760532c.726T>C1.000
rpoB760533p.Val243Arg1.000
rpoB760541c.735G>T0.982
rpoB760547c.741G>C1.000
rpoB760563p.Arg253Met1.000
rpoB760587p.Thr261Ala0.965
rpoB760591p.Val262Ala1.000
rpoB760593p.Gly263Ser1.000
rpoB760596p.Thr264Pro1.000
rpoB760611c.805T>C1.000
rpoB760649c.843G>C1.000
rpoB760655c.849A>G1.000
rpoB760658c.852G>A1.000
rpoB760661c.855A>C1.000
rpoB760670c.864G>T1.000
rpoB760674c.868T>C1.000
rpoB760679c.873A>G0.985
rpoB760683c.877T>C1.000
rpoB760715c.909C>G1.000
rpoB760718c.912C>G1.000
rpoB760721c.915C>G1.000
rpoB760730c.924T>C1.000
rpoB760734p.Val310Ile1.000
rpoB760916c.1110C>G1.000
rpoB760919c.1113C>T1.000
rpoB760925c.1119T>C1.000
rpoB760928c.1122G>C1.000
rpoB760931c.1125C>G1.000
rpoB760934c.1128C>T1.000
rpoB760946c.1140A>G1.000
rpoB760964c.1158C>T1.000
rpoB760965p.Met387Leu1.000
rpoB760970c.1164G>C1.000
rpoB760982c.1176G>C1.000
rpoB760991c.1185G>C1.000
rpoB761006c.1200C>T1.000
rpoB761015c.1209G>C1.000
rpoB761021c.1215G>C1.000
rpoB761027c.1221A>G1.000
rpoB761036c.1230G>C1.000
rpoB761037c.1231T>C1.000
rpoB761051c.1245G>C1.000
rpoB761096c.1290G>C1.000
rpoB761097c.1291A>T1.000
rpoB761102c.1296A>G1.000
rpoB761133c.1327T>C1.000
rpoB761150c.1344A>T1.000
rpoB761165c.1359G>A1.000
rpoB761168c.1362C>G1.000
rpoB761171c.1365C>T1.000
rpoB761180c.1374A>G1.000
rpoB761189c.1383T>G1.000
rpoB761195c.1389G>C1.000
rpoB761201c.1395G>A1.000
rpoB761204c.1398C>T1.000
rpoB761207c.1401C>T1.000
rpoB761222c.1416G>C1.000
rpoB761240c.1434C>T1.000
rpoB761249c.1443A>G1.000
rpoB761255c.1449T>G1.000
rpoB761258c.1452G>A1.000
rpoB761261c.1455G>C1.000
rpoB761282c.1476C>A1.000
rpoB761300c.1494G>A1.000
rpoB761306c.1500C>A1.000
rpoB761318c.1512G>C1.000
rpoB761327c.1521A>G1.000
rpoB761330c.1524G>C1.000
rpoB761345c.1539G>C1.000
rpoB761346p.Val514Asn1.000
rpoB761354c.1548C>T1.000
rpoB761360c.1554T>C1.000
rpoB761369p.Glu521Asp1.000
rpoB761374p.Val523Glu1.000
rpoB761408c.1602G>T1.000
rpoB761414c.1608A>G1.000
rpoB761423c.1617T>C1.000
rpoB761426c.1620G>A1.000
rpoB761430p.Ile542Leu1.000
rpoB761435p.Asp543Glu1.000
rpoB761437p.Ala544Asp1.000
rpoB761444c.1638T>C1.000
rpoB761451p.Val549Thr0.909
rpoB761457p.Pro551Asp1.000
rpoB761465c.1659G>T1.000
rpoB761474c.1668C>T1.000
rpoB761477c.1671C>T0.944
rpoB761482p.Ala559Gly1.000
rpoB761492c.1686G>C1.000
rpoB761502p.Pro566Ser1.000
rpoB761510c.1704T>C1.000
rpoB761516c.1710G>C1.000
rpoB761537c.1731C>G1.000
rpoB761540c.1734C>T1.000
rpoB761561c.1755C>G1.000
rpoB761564c.1758G>C1.000
rpoB761573c.1767C>G1.000
rpoB761579c.1773G>C1.000
rpoB761600c.1794T>C1.000
rpoB761606c.1800C>G1.000
rpoB761612c.1806G>T0.981
rpoB761615c.1809A>C1.000
rpoB761627c.1821C>T1.000
rpoB761636c.1830G>T1.000
rpoB761645c.1839C>G1.000
rpoB761648c.1842T>C1.000
rpoB761657c.1851C>A0.981
rpoB761669c.1863C>T0.812
rpoB761675c.1869G>C0.797
rpoB761687c.1881C>T1.000
rpoB761690c.1884G>C1.000
rpoB761711c.1905C>G1.000
rpoB761712p.Val636Ile1.000
rpoB761723p.Glu639Asp1.000
rpoB761724p.Glu640Lys1.000
rpoB761728p.Ser641Thr1.000
rpoB761732c.1926C>T1.000
rpoB761741c.1935G>A1.000
rpoB761750c.1944G>C1.000
rpoB761760p.Ile652Val1.000
rpoB761765c.1959T>G1.000
rpoB761772p.His656Ala1.000
rpoB761777c.1971C>T1.000
rpoB761778p.Asn658Asp1.000
rpoB761791p.Arg662Gln1.000
rpoB761813c.2007T>C1.000
rpoB761814p.Ala670Asn1.000
rpoB761834c.2028T>C1.000
rpoB761847p.Cys681Arg1.000
rpoB761852c.2046C>G1.000
rpoB761858c.2052G>C1.000
rpoB761864c.2058G>C1.000
rpoB761868p.Asp688Gln1.000
rpoB761873c.2067A>T1.000
rpoB761885c.2079T>C1.000
rpoB761897c.2091C>G1.000
rpoB761906c.2100C>G1.000
rpoB761912c.2106T>C1.000
rpoB761916p.Asp704Asn1.000
rpoB761930c.2124G>C1.000
rpoB761948c.2142G>C1.000
rpoB761954c.2148C>G1.000
rpoB761969c.2163G>A1.000
rpoB761972c.2166C>G1.000
rpoB762006c.2200C>A1.000
rpoB762024p.Val740Thr1.000
rpoB762029c.2223C>G1.000
rpoB762053c.2247T>C1.000
rpoB762062c.2256T>C1.000
rpoB762065c.2259T>C1.000
rpoB762083c.2277T>C1.000
rpoB762086c.2280G>C1.000
rpoB762101c.2295C>G1.000
rpoB762114p.Ile770Val1.000
rpoB762131c.2325C>G0.930
rpoB762134c.2328C>T0.925
rpoB762140c.2334G>C0.926
rpoB762143c.2337T>C1.000
rpoB762149c.2343G>C1.000
rpoB762158c.2352G>C1.000
rpoB762167c.2361T>C1.000
rpoB762176c.2370T>C1.000
rpoB762185c.2379G>C1.000
rpoB762212c.2406G>C1.000
rpoB762236c.2430G>C1.000
rpoB762254c.2448T>C1.000
rpoB762257c.2451C>G1.000
rpoB762266c.2460T>C1.000
rpoB762281c.2475G>A1.000
rpoB762284c.2478G>C1.000
rpoB762293c.2487T>C1.000
rpoB762314c.2508C>T1.000
rpoB762317c.2511A>G1.000
rpoB762329c.2523G>C1.000
rpoB762338c.2532T>C1.000
rpoB762347c.2541T>C1.000
rpoB762362p.Glu852Asp1.000
rpoB762369c.2563T>C1.000
rpoB762374c.2568G>C1.000
rpoB762380c.2574T>G1.000
rpoB762398c.2592T>C1.000
rpoB762401c.2595G>C1.000
rpoB762404c.2598T>C1.000
rpoB762407c.2601G>C1.000
rpoB762410c.2604T>G1.000
rpoB762416c.2610A>G1.000
rpoB762449c.2643C>T1.000
rpoB762452c.2646G>T0.985
rpoB762470c.2664G>C1.000
rpoB762490p.Val895Ala1.000
rpoB762509c.2703T>G0.980
rpoB762510p.Ala902Pro0.980
rpoB762527c.2721G>C1.000
rpoB762533c.2727T>C1.000
rpoB762536c.2730T>C1.000
rpoB762537c.2731T>C1.000
rpoB762551c.2745C>T1.000
rpoB762560c.2754A>T1.000
rpoB762563c.2757G>T1.000
rpoB762575c.2769C>T0.966
rpoB762725c.2919C>T1.000
rpoB762728c.2922C>G1.000
rpoB762730p.Gln975Arg1.000
rpoB762753c.2947T>C1.000
rpoB762758c.2952G>C1.000
rpoB762760p.Cys985Ser1.000
rpoB762768p.Pro988Ala1.000
rpoB762782c.2976T>C1.000
rpoB762785p.Asp993Glu1.000
rpoB762788c.2982G>C1.000
rpoB762789p.Leu995Met1.000
rpoB762795p.Asp997Asn1.000
rpoB762799p.Ala998Gly1.000
rpoB762812c.3006C>G1.000
rpoB762818c.3012C>G1.000
rpoB762827c.3021G>T1.000
rpoB762831c.3025A>T1.000
rpoB762836c.3030C>T1.000
rpoB762857c.3051C>G1.000
rpoB762860c.3054G>C1.000
rpoB762917c.3111C>G1.000
rpoB762920c.3114C>T1.000
rpoB762926c.3120C>G0.970
rpoB762929c.3123G>C0.958
rpoB762953c.3147G>A0.986
rpoB762995c.3189G>T1.000
rpoB763028c.3222T>C1.000
rpoB763031c.3225T>G1.000
rpoB763034c.3228C>G1.000
rpoB763040c.3234C>G1.000
rpoB763050c.3244C>T1.000
rpoB763053c.3247T>C1.000
rpoB763058c.3252C>G1.000
rpoB763070c.3264T>C1.000
rpoB763076c.3270C>G1.000
rpoB763085c.3279C>T1.000
rpoB763094c.3288G>C1.000
rpoB763115c.3309T>C1.000
rpoB763127c.3321G>C1.000
rpoB763136c.3330C>T1.000
rpoB763142c.3336C>G1.000
rpoB763148c.3342G>C1.000
rpoB763169c.3363A>G1.000
rpoB763193c.3387C>T1.000
rpoB763202c.3396A>G1.000
rpoB763203p.Ser1133Ala1.000
rpoB763207p.Ser1134Lys1.000
rpoB763227c.3421C>T1.000
rpoB763238c.3432T>C1.000
rpoB763262c.3456C>A1.000
rpoB763265c.3459G>C1.000
rpoB763283c.3477T>C1.000
rpoB763304c.3498A>T1.000
rpoB763305c.3499A>T1.000
rpoB763310c.3504C>G1.000
rpoB763313c.3507G>A1.000
rpoB763316c.3510T>C1.000
rpoB763319c.3513T>C1.000
rpoB763322c.3516G>T1.000
rpoB763325763325A>T1.000
rpoC763351c.-19T>C1.000
rpoC763352c.-18T>A1.000
rpoC763396c.27A>G1.000
rpoC763408c.39T>C1.000
rpoC763411c.42T>G1.000
rpoC763414c.45T>G1.000
rpoC763430c.61A>C1.000
rpoC763444c.75T>C1.000
rpoC763447c.78C>T1.000
rpoC763456c.87A>G1.000
rpoC763465c.96G>A1.000
rpoC763486c.117T>C1.000
rpoC763492c.123G>C1.000
rpoC763501c.132C>T1.000
rpoC763528c.159G>A1.000
rpoC763546c.177A>G1.000
rpoC763570c.201G>C1.000
rpoC763594c.225C>T1.000
rpoC763603c.234C>T1.000
rpoC763618c.249C>T1.000
rpoC763657c.288G>A0.989
rpoC763660c.291T>G1.000
rpoC763666c.297G>T1.000
rpoC763669c.300C>G1.000
rpoC763696c.327T>C1.000
rpoC763702c.333C>G1.000
rpoC763708c.339G>C1.000
rpoC763709c.340C>T1.000
rpoC763714c.345G>C1.000
rpoC763717c.348T>C1.000
rpoC763732c.363C>G1.000
rpoC763735c.366G>C1.000
rpoC763744c.375G>C1.000
rpoC763747c.378G>A1.000
rpoC763765c.396T>G1.000
rpoC763781c.412T>A1.000
rpoC763790p.Glu141Thr1.000
rpoC763795p.Glu142Asp1.000
rpoC763807c.438T>C1.000
rpoC763813c.444C>G1.000
rpoC763822c.453C>G1.000
rpoC763825c.456G>A1.000
rpoC763831c.462A>G1.000
rpoC763836p.Ala156Val1.000
rpoC763840c.471G>C1.000
rpoC763844p.Arg159Lys1.000
rpoC763858c.489A>G1.000
rpoC763867c.498C>G1.000
rpoC763872p.Gly168Ala1.000
rpoC763876p.Glu169Asp0.980
rpoC763879c.510A>G1.000
rpoC763888c.519G>C1.000
rpoC763891c.522G>C1.000
rpoC763894c.525A>G1.000
rpoC763900c.531G>C1.000
rpoC763933c.564C>T1.000
rpoC763936c.567C>G1.000
rpoC763939c.570G>A0.988
rpoC763947p.Ala193Val1.000
rpoC763951c.582G>C1.000
rpoC763963c.594C>T1.000
rpoC763978c.609C>T1.000
rpoC763987c.618C>T1.000
rpoC763991p.Ile208Leu1.000
rpoC763996c.627T>C1.000
rpoC764002c.633C>T1.000
rpoC764005c.636G>C1.000
rpoC764023c.654G>C1.000
rpoC764024c.655T>C1.000
rpoC764029p.Glu220Asp1.000
rpoC764030p.Asp221Asn1.000
rpoC764039p.Ser224Asp1.000
rpoC764044c.675T>C1.000
rpoC764048p.Thr227Val1.000
rpoC764059c.690G>T1.000
rpoC764083c.714A>G1.000
rpoC764085p.Asn239Thr1.000
rpoC764087p.Leu240Val1.000
rpoC764098c.729A>G1.000
rpoC764101c.732C>G1.000
rpoC764104c.735C>G1.000
rpoC764110c.741C>T1.000
rpoC764140c.771C>T1.000
rpoC764143c.774G>C1.000
rpoC764161c.792G>C1.000
rpoC764169p.Asn267Thr1.000
rpoC764188c.819A>G1.000
rpoC764195p.Ser276Leu1.000
rpoC764203c.834G>C1.000
rpoC764206c.837T>C1.000
rpoC764207p.Val280Ile1.000
rpoC764213p.Arg282Lys1.000
rpoC764242c.873C>T1.000
rpoC764245c.876C>T0.974
rpoC764254c.885G>C1.000
rpoC764257c.888G>C1.000
rpoC764266c.897T>C1.000
rpoC764269c.900G>C1.000
rpoC764272c.903G>C1.000
rpoC764278c.909A>G1.000
rpoC764287c.918C>T1.000
rpoC764293c.924G>C1.000
rpoC764317c.948C>G0.611
rpoC764320c.951C>G1.000
rpoC764344c.975C>T1.000
rpoC764365c.996C>T1.000
rpoC764368c.999C>T1.000
rpoC764371c.1002G>C1.000
rpoC764377c.1008C>G1.000
rpoC764380c.1011G>C1.000
rpoC764387c.1018T>C1.000
rpoC764405c.1036A>C1.000
rpoC764410c.1041G>C1.000
rpoC764428c.1059G>C1.000
rpoC764431c.1062G>C1.000
rpoC764434c.1065A>G1.000
rpoC764435c.1066A>C1.000
rpoC764446c.1077T>C1.000
rpoC764449c.1080G>C1.000
rpoC764452c.1083T>C1.000
rpoC764455c.1086G>C1.000
rpoC764458c.1089G>C1.000
rpoC764461c.1092A>G1.000
rpoC764497c.1128A>G1.000
rpoC764503c.1134G>C1.000
rpoC764521c.1152T>C1.000
rpoC764527c.1158C>T1.000
rpoC764539c.1170C>G1.000
rpoC764548c.1179G>A1.000
rpoC764566c.1197C>G1.000
rpoC764573c.1204C>T1.000
rpoC764576c.1207T>A1.000
rpoC764581c.1212T>C1.000
rpoC764611c.1242G>T1.000
rpoC764626c.1257C>T1.000
rpoC764650c.1281G>T0.988
rpoC764656c.1287C>G1.000
rpoC764668c.1299C>T0.989
rpoC764695c.1326T>C1.000
rpoC764719c.1350G>A1.000
rpoC764746c.1377G>A1.000
rpoC764752c.1383G>T1.000
rpoC764764c.1395T>C1.000
rpoC764791c.1422C>G1.000
rpoC764803c.1434C>G1.000
rpoC764809c.1440C>T1.000
rpoC764812c.1443C>G1.000
rpoC764815c.1446A>G1.000
rpoC764824c.1455T>C1.000
rpoC764827c.1458G>C1.000
rpoC764858c.1489T>C1.000
rpoC764863c.1494G>C1.000
rpoC764869c.1500C>T1.000
rpoC764875c.1506C>T1.000
rpoC764878c.1509C>G1.000
rpoC764887c.1518G>C1.000
rpoC764888c.1519T>C1.000
rpoC764896c.1527C>T1.000
rpoC764911c.1542A>G1.000
rpoC764912p.Met515Gln1.000
rpoC764948c.1579T>C1.000
rpoC764962c.1593G>C1.000
rpoC764968c.1599T>C1.000
rpoC765007c.1638T>G1.000
rpoC765008c.1639T>C1.000
rpoC765019c.1650A>G1.000
rpoC765034c.1665T>C1.000
rpoC765040c.1671T>C1.000
rpoC765041c.1672T>C1.000
rpoC765047c.1678T>C1.000
rpoC765052c.1683C>G1.000
rpoC765053c.1684T>A1.000
rpoC765076c.1707A>C1.000
rpoC765079c.1710T>G1.000
rpoC765082c.1713G>T0.979
rpoC765089c.1720T>C1.000
rpoC765100c.1731G>C1.000
rpoC765103c.1734G>A1.000
rpoC765115c.1746G>T1.000
rpoC765121c.1752G>T1.000
rpoC765196c.1827T>C1.000
rpoC765199c.1830T>C1.000
rpoC765202c.1833C>G1.000
rpoC765208c.1839T>C1.000
rpoC765220c.1851A>G1.000
rpoC765232c.1863G>C1.000
rpoC765234p.Ala622Val1.000
rpoC765246p.Val626Ala1.000
rpoC765277c.1908G>T1.000
rpoC765281p.Thr638Asp1.000
rpoC765300p.Val644Ala1.000
rpoC765305p.Ile646Val1.000
rpoC765311p.Ala648Thr1.000
rpoC765317c.1948C>T1.000
rpoC765326p.His653Glu1.000
rpoC765330p.Ser654Asn1.000
rpoC765339p.Gln657Arg1.000
rpoC765348p.Asp660Gly1.000
rpoC765350p.Ala661Ser1.000
rpoC765358p.Met663Ile1.000
rpoC765383p.Met672Leu1.000
rpoC765404p.Leu679Thr1.000
rpoC765409c.2040T>C1.000
rpoC765412c.2043T>C1.000
rpoC765421c.2052C>G1.000
rpoC765445c.2076G>T1.000
rpoC765453p.Ala695Val1.000
rpoC765478c.2109T>C1.000
rpoC765533p.Tyr722His1.000
rpoC765547c.2178C>T1.000
rpoC765548c.2179A>T1.000
rpoC765553c.2184C>A1.000
rpoC765556c.2187G>C1.000
rpoC765562c.2193G>C1.000
rpoC765611p.His748Ser1.000
rpoC765625c.2256C>T1.000
rpoC765628c.2259G>C1.000
rpoC765635p.Val756Leu1.000
rpoC765640c.2271A>G1.000
rpoC765658c.2289C>T1.000
rpoC765662c.2293T>C1.000
rpoC765669p.His767Arg1.000
rpoC765673p.Asp768Glu1.000
rpoC765700c.2331T>C1.000
rpoC765718p.Asp783Glu1.000
rpoC765721c.2352G>A1.000
rpoC765724c.2355C>G1.000
rpoC765734c.2365T>C1.000
rpoC765739c.2370G>T1.000
rpoC765742p.Glu791Asp1.000
rpoC765751c.2382C>G1.000
rpoC765753p.Asp795Ala1.000
rpoC765772c.2403C>G1.000
rpoC765787c.2418C>T1.000
rpoC765790c.2421C>T1.000
rpoC765793c.2424C>G1.000
rpoC765796c.2427C>T1.000
rpoC765811c.2442T>C1.000
rpoC765814c.2445A>G1.000
rpoC765826c.2457T>C1.000
rpoC765835c.2466C>T1.000
rpoC765871c.2502T>C1.000
rpoC765875p.Val836Ile1.000
rpoC765886c.2517C>T1.000
rpoC765904c.2535C>G1.000
rpoC765908c.2539C>T0.985
rpoC765937c.2568T>C1.000
rpoC765967c.2598C>T1.000
rpoC765979c.2610C>G1.000
rpoC765982c.2613C>T1.000
rpoC765991c.2622C>G1.000
rpoC765994c.2625A>T1.000
rpoC766003c.2634G>C1.000
rpoC766006c.2637C>T1.000
rpoC766009c.2640G>T1.000
rpoC766012c.2643C>G1.000
rpoC766043p.Gln892Gly1.000
rpoC766061p.Val898Ile1.000
rpoC766270c.2901G>C1.000
rpoC766273c.2904T>C1.000
rpoC766280p.Ser971Gly1.000
rpoC766288c.2919C>G1.000
rpoC766291c.2922G>T1.000
rpoC766294c.2925C>T1.000
rpoC766297c.2928G>C1.000
rpoC766309c.2940G>C1.000
rpoC766312c.2943T>A1.000
rpoC766315c.2946C>G1.000
rpoC766348c.2979A>G1.000
rpoC766351c.2982C>G1.000
rpoC766363c.2994G>C1.000
rpoC766381c.3012C>T1.000
rpoC766384c.3015A>G1.000
rpoC766390c.3021C>T1.000
rpoC766408c.3039C>T1.000
rpoC766426c.3057C>T1.000
rpoC766435p.Glu1022Asp1.000
rpoC766456c.3087C>G1.000
rpoC766459c.3090G>T1.000
rpoC766484p.Val1039Ile1.000
rpoC766492c.3123T>C1.000
rpoC766517p.Thr1050Ala0.469
rpoC766522c.3153C>A0.458
rpoC766528c.3159T>G1.000
rpoC766530p.Arg1054Gln1.000
rpoC766537c.3168G>A1.000
rpoC766540p.Asp1057Glu1.000
rpoC766547p.Arg1060Lys1.000
rpoC766564c.3195C>G1.000
rpoC766570c.3201T>G1.000
rpoC766573c.3204T>G1.000
rpoC766576c.3207C>T1.000
rpoC766582c.3213C>T0.964
rpoC766585c.3216T>C1.000
rpoC766607p.Ile1080Leu1.000
rpoC766610p.Ser1081Pro1.000
rpoC766618c.3249G>T1.000
rpoC766630c.3261G>T1.000
rpoC766645c.3276A>G1.000
rpoC766651c.3282T>C1.000
rpoC766654c.3285C>G1.000
rpoC766657c.3288A>G1.000
rpoC766661p.Val1098Leu1.000
rpoC766666c.3297C>G1.000
rpoC766672c.3303T>C1.000
rpoC766690c.3321G>C1.000
rpoC766702c.3333G>C1.000
rpoC766708c.3339A>G1.000
rpoC766726c.3357T>C1.000
rpoC766738c.3369G>T1.000
rpoC766750c.3381C>G1.000
rpoC766765c.3396A>C1.000
rpoC766774c.3405T>C1.000
rpoC766775p.Arg1136Asn1.000
rpoC766787p.Glu1140Gln1.000
rpoC766798c.3429C>G1.000
rpoC766804c.3435A>G1.000
rpoC766843c.3474T>C1.000
rpoC766846c.3477C>G1.000
rpoC766883p.Ser1172Ala1.000
rpoC766894c.3525T>C1.000
rpoC766895c.3526T>C1.000
rpoC766900c.3531T>C1.000
rpoC766903c.3534C>T1.000
rpoC766911p.Ile1181Thr1.000
rpoC766915p.Asp1182Glu1.000
rpoC766918c.3549C>G1.000
rpoC766921c.3552G>C1.000
rpoC766931p.Ala1188Thr1.000
rpoC766935p.Glu1189Ala1.000
rpoC766942c.3573C>T1.000
rpoC766945c.3576A>G1.000
rpoC766961p.Gly1198Leu1.000
rpoC766978c.3609C>A0.980
rpoC766996c.3627C>T1.000
rpoC767002c.3633G>C1.000
rpoC767020c.3651C>G1.000
rpoC767023c.3654C>T1.000
rpoC767041c.3672G>C1.000
rpoC767044c.3675G>C1.000
rpoC767059c.3690T>C1.000
rpoC767098c.3729T>C1.000
rpoC767104c.3735C>G1.000
rpoC767105p.Asn1246Gln1.000
rpoC767110c.3741T>C1.000
rpoC767119c.3750A>G1.000
rpoC767152c.3783T>C1.000
rpoC767158c.3789T>C1.000
rpoC767167c.3798C>G1.000
rpoC767182c.3813G>C1.000
rpoC767197c.3828G>A1.000
rpoC767206c.3837C>G1.000
rpoC767209c.3840T>C1.000
rpoC767212c.3843G>C1.000
rpoC767221c.3852C>G1.000
rpoC767230c.3861G>C1.000
rpoC767233c.3864T>C1.000
rpoC767263c.3894T>C1.000
rpoC767266c.3897G>C0.659
rpoC767278c.3909T>C0.632
rpoC767281c.3912C>G0.622
rpoC767284c.3915C>T1.000
rpoC767302c.3933C>G1.000
rpsL781571c.12C>T1.000
rpsL781586c.27C>T1.000
rpsL781592c.33T>C1.000
rpsL781595c.36T>C1.000
rpsL781598c.39G>C1.000
rpsL781605p.Ile16Val1.000
rpsL781608p.Ser17Ala1.000
rpsL781616c.57C>G1.000
rpsL781628c.69T>C0.990
rpsL781631c.72G>C1.000
rpsL781649c.90T>A1.000
rpsL781652c.93T>G1.000
rpsL781655c.96T>G0.970
rpsL781658c.99A>G1.000
rpsL781682c.123T>C1.000
rpsL781709c.150G>C1.000
rpsL781715c.156T>G1.000
rpsL781718c.159C>G1.000
rpsL781724c.165G>C1.000
rpsL781728c.169T>C1.000
rpsL781733c.174G>C1.000
rpsL781736c.177T>C1.000
rpsL781742c.183C>G1.000
rpsL781748c.189C>G1.000
rpsL781751c.192G>C1.000
rpsL781754c.195G>C1.000
rpsL781760c.201T>C1.000
rpsL781763c.204C>G1.000
rpsL781766c.207C>T1.000
rpsL781772c.213C>T1.000
rpsL781808c.249C>T1.000
rpsL781811c.252C>T1.000
rpsL781814c.255C>T1.000
rpsL781817c.258G>T1.000
rpsL781832c.273T>G1.000
rpsL781859c.300T>C1.000
rpsL781868c.309T>C1.000
rpsL781871c.312G>C1.000
rpsL781877c.318T>A1.000
rpsL781892c.333A>G1.000
rpsL781898c.339A>C1.000
rpsL781907c.348T>C1.000
rpsL781916c.357T>G1.000
rpsL781929p.Gly124Ser0.982
rplC800907c.99C>A1.000
rplC800916c.108A>G1.000
rplC800928c.120C>T1.000
rplC800931c.123G>C1.000
rplC800937c.129A>G1.000
rplC800946c.138T>C1.000
rplC800949c.141T>C1.000
rplC800964c.156G>C1.000
rplC800970c.162T>C1.000
rplC800985c.177A>C1.000
rplC800994c.186C>G1.000
rplC801147c.339T>C1.000
rplC801150c.342G>C1.000
rplC801153c.345G>C1.000
rplC801156c.348T>A1.000
rplC801171c.363A>G1.000
rplC801174c.366T>C1.000
rplC801176p.Phe123Tyr1.000
rplC801207c.399C>G1.000
rplC801210c.402T>C1.000
rplC801220p.Ser138Gly1.000
rplC801228c.420T>C1.000
rplC801231c.423C>T1.000
rplC801249c.441T>G1.000
rplC801255c.447C>T1.000
rplC801258c.450C>G1.000
rplC801307p.Ala167Ser1.000
rplC801312c.504G>C1.000
rrs1471923r.78t>c1.000
rrs1471925r.80t>c1.000
rrs1471932r.87a>g1.000
rrs1471934r.89a>g1.000
rrs1471986r.141c>t1.000
rrs1472019r.174g>a1.000
rrs1472031r.186g>c1.000
rrs1472033r.188a>c1.000
rrs1472035r.190g>t0.992
rrs1472040r.195t>g1.000
rrs1472041r.196c>t1.000
rrs1472042r.197t>g1.000
rrs1472053r.208agc>a1.000
rrs1472061r.216a>t0.994
rrs1472075r.230a>g1.000
rrs1472106r.261g>a1.000
rrs1472108r.263c>t1.000
rrs1472286r.441c>g1.000
rrs1472287r.442c>t1.000
rrs1472292r.447a>g1.000
rrs1472298r.453g>c1.000
rrs1472304r.459g>a1.000
rrs1472311r.466c>t0.990
rrs1472314r.469a>g1.000
rrs1472315r.470t>g1.000
rrs1472327r.482g>a1.000
rrs1472328r.483g>c1.000
rrs1472431r.586g>a1.000
rrs1472438r.593t>c1.000
rrs1472446r.601t>a1.000
rrs1472452r.607g>a1.000
rrs1472464r.619a>g1.000
rrs1472489r.644a>g1.000
rrs1472498r.653c>t1.000
rrs1472683r.838t>tta0.994
rrs1472847r.1002g>c1.000
rrs1472848r.1003t>g1.000
rrs1472849r.1004c>g1.000
rrs1472858r.1013g>t1.000
rrs1472859r.1014g>c1.000
rrs1472860r.1015c>g1.000
rrs1472973r.1128a>t1.000
rrs1473100r.1255g>c1.000
rrs1473104r.1259c>t1.000
rrs1473109r.1264t>g0.982
rrs1473111r.1266a>t1.000
rrs1473123r.1278a>t1.000
rrs1473145r.1300c>t1.000
rrs1473166r.1321g>a1.000
rrs1473276r.1431a>g1.000
rrs1473290r.1445c>t1.000
rrs1473291r.1446g>gt0.993
rrs1473301r.1456t>c1.000
rrl1473567c.-91A>T0.980
rrl1473568c.-90G>T1.000
rrl1473569c.-89A>T1.000
rrl1473570c.-88A>T1.000
rrl1473571c.-87C>G1.000
rrl1473668r.11c>t1.000
rrl1473717r.60g>a1.000
rrl1473746r.89t>c1.000
rrl1473770r.113t>g1.000
rrl1473788r.131a>g1.000
rrl1473806r.149c>t1.000
rrl1473807r.150t>c1.000
rrl1473811r.154c>a1.000
rrl1473812r.155g>a1.000
rrl1473814r.157a>t1.000
rrl1473815r.158t>g1.000
rrl1473816r.159c>g1.000
rrl1473822r.165a>g1.000
rrl1473827r.170g>gcc1.000
rrl1473828r.171g>a1.000
rrl1473839r.182g>t1.000
rrl1473876r.219g>a1.000
rrl1473887r.230t>a1.000
rrl1473898r.241c>t1.000
rrl1473899r.242a>g1.000
rrl1473916r.259c>a1.000
rrl1473922r.265a>g1.000
rrl1473923r.266c>g1.000
rrl1473924r.267a>at1.000
rrl1473935r.278c>t1.000
rrl1473937r.280c>t1.000
rrl1473943r.286g>t1.000
rrl1473945r.288t>a1.000
rrl1473946r.289a>t1.000
rrl1473983r.326a>t1.000
rrl1473984r.327t>c1.000
rrl1473989r.332ct>c1.000
rrl1473992r.335a>g1.000
rrl1473994r.337c>t1.000
rrl1473995r.338g>t1.000
rrl1474001r.344c>t1.000
rrl1474005r.348t>c1.000
rrl1474011r.354g>a0.167
rrl1474016r.359c>g1.000
rrl1474026r.369c>t1.000
rrl1474045r.388c>t1.000
rrl1474054r.397t>c1.000
rrl1474083r.426c>t1.000
rrl1474093r.436g>a1.000
rrl1474094r.437c>t1.000
rrl1474100r.443c>t1.000
rrl1474103r.446a>t1.000
rrl1474108r.451c>g1.000
rrl1474110r.453a>t1.000
rrl1474140r.483c>t1.000
rrl1474151r.494c>t1.000
rrl1474174r.517a>g1.000
rrl1474181r.524c>a1.000
rrl1474249r.592g>t1.000
rrl1474263r.606g>a1.000
rrl1474290r.633t>c0.990
rrl1474303r.646a>t1.000
rrl1474306r.649a>t1.000
rrl1474350r.693g>c1.000
rrl1474351r.694g>c1.000
rrl1474353r.696a>g1.000
rrl1474356r.699t>c1.000
rrl1474362r.705a>g1.000
rrl1474413r.756acccacac>a1.000
rrl1474421r.764g>t1.000
rrl1474427r.770a>c1.000
rrl1474430r.773c>g1.000
rrl1474432r.775c>g1.000
rrl1474437r.780gaa>g1.000
rrl1474438r.781a>t1.000
rrl1474439r.782a>g1.000
rrl1474452r.795c>g1.000
rrl1474552r.895c>t1.000
rrl1474632r.975g>t1.000
rrl1474636r.979a>t1.000
rrl1474638r.981c>a1.000
rrl1474639r.982g>c1.000
rrl1474640r.983c>t1.000
rrl1474715r.1058ta>t0.618
rrl1474753r.1096a>g1.000
rrl1474760r.1103a>g1.000
rrl1474794r.1137c>a1.000
rrl1474812r.1155g>a0.991
rrl1474830r.1173a>t1.000
rrl1474831r.1174a>t1.000
rrl1474956r.1299c>a1.000
rrl1474968r.1311g>a1.000
rrl1474969r.1312g>a1.000
rrl1474972r.1315g>t1.000
rrl1474990r.1333c>t1.000
rrl1474991r.1334t>g1.000
rrl1474995r.1338t>c1.000
rrl1474997r.1340a>g1.000
rrl1474999r.1342c>t1.000
rrl1475008r.1351c>a1.000
rrl1475010r.1353g>a1.000
rrl1475016r.1359c>t1.000
rrl1475017r.1360g>a1.000
rrl1475031r.1374g>t1.000
rrl1475061r.1404c>t1.000
rrl1475062r.1405a>g1.000
rrl1475120r.1463g>t0.983
rrl1475202r.1545g>c1.000
rrl1475209r.1552g>a1.000
rrl1475213r.1556c>t1.000
rrl1475221r.1564c>t1.000
rrl1475240r.1583c>g1.000
rrl1475241r.1584c>g1.000
rrl1475242r.1585g>t1.000
rrl1475244r.1587a>g1.000
rrl1475252r.1595c>a1.000
rrl1475257r.1600c>t0.964
rrl1475266r.1609t>c0.964
rrl1475268r.1611t>a1.000
rrl1475269r.1612g>c0.964
rrl1475278r.1621g>c0.966
rrl1475279r.1622g>c0.966
rrl1475291r.1634a>c1.000
rrl1475315r.1658a>t1.000
rrl1475355r.1698c>t1.000
rrl1475369r.1712g>c1.000
rrl1475375r.1718g>a1.000
rrl1475376r.1719a>c1.000
rrl1475378r.1721a>t1.000
rrl1475379r.1722g>c1.000
rrl1475380r.1723c>a1.000
rrl1475399r.1742t>a1.000
rrl1475400r.1743c>t1.000
rrl1475406r.1749t>g1.000
rrl1475407r.1750c>t1.000
rrl1475409r.1752t>c1.000
rrl1475419r.1762c>t0.994
rrl1475429r.1772g>a0.994
rrl1475433r.1776a>c1.000
rrl1475452r.1795c>a1.000
rrl1475460r.1803a>g1.000
rrl1475480r.1823a>t0.995
rrl1475505r.1848g>a1.000
rrl1475526r.1869c>a1.000
rrl1475544r.1887a>t1.000
rrl1475573r.1916g>a0.993
rrl1475602r.1945g>c1.000
rrl1475603r.1946g>t1.000
rrl1475604r.1947a>c1.000
rrl1475608r.1951t>c1.000
rrl1475612r.1955g>c1.000
rrl1475614r.1957a>t1.000
rrl1475615r.1958c>g1.000
rrl1475616r.1959a>g1.000
rrl1475619r.1962c>t1.000
rrl1475621r.1964t>c1.000
rrl1475626r.1969t>c1.000
rrl1475629r.1972g>c1.000
rrl1475637r.1980t>g1.000
rrl1475638r.1981c>g1.000
rrl1475639r.1982c>g1.000
rrl1475659r.2002g>a1.000
rrl1475753r.2096c>g1.000
rrl1475762r.2105g>t1.000
rrl1475763r.2106c>t1.000
rrl1475764r.2107a>c1.000
rrl1475765r.2108a>g1.000
rrl1475775r.2118g>t1.000
rrl1475916r.2259c>t1.000
rrl1475975r.2318c>t1.000
rrl1475977r.2320a>g1.000
rrl1475995r.2338g>a0.994
rrl1475997r.2340a>g1.000
rrl1476030r.2373ac>a0.994
rrl1476035r.2378g>gc0.987
rrl1476044r.2387t>g1.000
rrl1476045r.2388g>t1.000
rrl1476049r.2392c>t1.000
rrl1476086r.2429g>a1.000
rrl1476088r.2431a>c1.000
rrl1476095r.2438c>t1.000
rrl1476103r.2446c>a1.000
rrl1476108r.2451t>g1.000
rrl1476110r.2453g>t1.000
rrl1476115r.2458t>c1.000
rrl1476131r.2474c>t1.000
rrl1476214r.2557g>t1.000
rrl1476215r.2558c>t1.000
rrl1476224r.2567a>g1.000
rrl1476245r.2588c>t1.000
rrl1476246r.2589g>a1.000
rrl1476252r.2595t>g1.000
rrl1476256r.2599a>c1.000
rrl1476262r.2605g>a1.000
rrl1476281r.2624t>c1.000
rrl1476529r.2872a>t1.000
rrl1476583r.2926g>a1.000
rrl1476584r.2927c>t1.000
rrl1476594r.2937c>t1.000
rrl1476597r.2940g>a1.000
rrl1476603r.2946g>a1.000
rrl1476608r.2951c>g1.000
rrl1476616r.2959a>g1.000
rrl1476619r.2962c>t1.000
rrl1476628r.2971t>a1.000
rrl1476665r.3008t>a1.000
rrl1476674r.3017t>c1.000
rrl1476679r.3022t>a1.000
rrl1476689r.3032a>t1.000
rrl1476690r.3033c>t1.000
rrl1476693r.3036g>a1.000
rrl1476695r.3038t>a1.000
rrl1476716r.3059a>c1.000
rrl1476717r.3060c>t1.000
rrl1476723r.3066t>a1.000
rrl1476725r.3068c>t1.000
rrl1476726r.3069a>g1.000
rrl1476731r.3074g>a1.000
rrl1476732r.3075t>c1.000
rrl1476746r.3089t>a1.000
rrl1476748r.3091a>c1.000
rrl1476750r.3093t>c1.000
rrl1476753r.3096t>g1.000
rrl1476755r.3098g>t0.986
rrl1476759r.3102t>c0.987
rrl1476759r.3102t>tgc0.693
rrl1476770r.3113t>c1.000
rrl1476771r.3114g>a1.000
fabG11673490c.51A>G1.000
fabG11673496c.57G>C1.000
fabG11673499c.60T>C1.000
fabG11673505c.66A>T1.000
fabG11673517c.78G>C0.514
fabG11673523c.84G>A0.521
fabG11673535c.96A>G1.000
fabG11673541c.102G>A1.000
fabG11673547c.108T>C1.000
fabG11673633p.Ser65Asn1.000
fabG11673646c.207T>C1.000
fabG11673652c.213C>T0.941
fabG11673657p.Thr73Lys1.000
fabG11673660p.Ala74Glu1.000
fabG11673664c.225A>C1.000
fabG11673667c.228A>G1.000
fabG11673679c.240T>C1.000
fabG11673682c.243G>C1.000
fabG11673698p.Ser87Ala1.000
fabG11673710p.Leu91Ile1.000
fabG11673716p.Ala93Lys1.000
fabG11673724c.285A>G0.976
fabG11673730c.291C>G1.000
fabG11673748c.309A>G1.000
fabG11673749p.Lys104Arg1.000
fabG11673757c.318G>A1.000
fabG11673758p.Lys107Glu1.000
fabG11673784c.345G>C1.000
fabG11673787c.348G>T1.000
fabG11673796c.357G>C1.000
fabG11673797p.Ala120Thr1.000
fabG11673802c.363A>G1.000
fabG11673808c.369A>C1.000
fabG11673877c.438C>G1.000
fabG11673901c.462A>G1.000
fabG11673904c.465C>G1.000
fabG11673905p.Ser156Ala1.000
fabG11673913c.474C>G1.000
fabG11673916c.477A>T1.000
fabG11673917p.Val160Leu1.000
fabG11673922c.483T>C1.000
fabG11673941p.Ala168Ser1.000
fabG11673955c.516G>C1.000
fabG11673961c.522A>C1.000
fabG11673962p.Asn175Gly1.000
fabG11673967c.528G>C1.000
fabG11673973c.534G>C1.000
fabG11673976c.537T>C1.000
fabG11673979c.540G>C1.000
fabG11673982c.543G>C1.000
fabG11673985c.546C>G1.000
fabG11673988c.549G>C1.000
fabG11674006p.Asp189Glu1.000
inhA1674337c.136C>T1.000
inhA1674342c.141T>C1.000
inhA1674353p.Thr51Ile1.000
inhA1674369c.168A>G1.000
inhA1674370p.Lys57Pro1.000
inhA1674375c.174C>G1.000
inhA1674387c.186A>G1.000
inhA1674399c.198A>G1.000
inhA1674416p.Ala72Gly1.000
inhA1674418c.217A>T1.000
inhA1674428p.Gly76Glu1.000
inhA1674435c.234G>C1.000
inhA1674443p.Ala81Val1.000
inhA1674450c.249G>C1.000
inhA1674452p.Ala84Glu1.000
inhA1674471c.270G>C1.000
inhA1674480c.279T>C1.000
inhA1674483c.282G>C1.000
inhA1674486c.285T>C1.000
inhA1674489c.288G>C1.000
inhA1674531c.330C>T1.000
inhA1674534c.333G>C1.000
inhA1674542p.Ala114Glu0.965
inhA1674546c.345T>C1.000
inhA1674549c.348G>C1.000
inhA1674550p.Ser117Ala1.000
inhA1674573c.372G>C1.000
inhA1674576c.375T>C1.000
inhA1674579c.378G>C1.000
inhA1674585c.384T>C1.000
inhA1674589p.Met130Leu1.000
inhA1674594c.393C>T1.000
inhA1674597c.396G>A1.000
inhA1674601p.Leu134Val1.000
inhA1674624c.423A>C1.000
inhA1674627c.426T>C1.000
inhA1674628p.Ser143Gly1.000
inhA1674656p.Ser152Thr1.000
inhA1674690c.489C>G1.000
inhA1674699c.498C>T0.964
inhA1674702c.501G>C1.000
inhA1674703c.502T>C1.000
inhA1674714c.513C>G1.000
inhA1674718c.517A>C1.000
inhA1674745p.Tyr182Val1.000
inhA1674750c.549T>C1.000
inhA1674756c.555T>G1.000
inhA1674765c.564C>G1.000
inhA1674771c.570C>G1.000
inhA1674774c.573A>C1.000
inhA1674777c.576C>G1.000
inhA1674780c.579T>G1.000
inhA1674801c.600T>C1.000
inhA1674804c.603G>C1.000
inhA1674810c.609C>G1.000
inhA1674819c.618G>C1.000
inhA1674825c.624C>T1.000
inhA1674828c.627G>A1.000
inhA1674830p.Glu210Gly1.000
inhA1674839p.Ala213Glu1.000
inhA1674848p.Gln216Arg1.000
inhA1674858c.657G>A1.000
inhA1674870c.669T>C1.000
inhA1674876c.675C>G1.000
inhA1674879c.678T>C1.000
inhA1674892p.Asn231Asp1.000
inhA1674903c.702T>C1.000
inhA1674904p.Ala235Pro1.000
inhA1674915c.714C>G1.000
inhA1674924c.723G>C1.000
inhA1674927c.726G>C1.000
inhA1674942c.741T>C1.000
inhA1674955p.Ala252Ser1.000
inhA1674965p.Gly255Val0.769
inhA1674987c.786C>T1.000
inhA1675002c.801A>G1.000
inhA16750101675010AGAACG>A1.000
rpsA1833538c.-4CA>C1.000
rpsA1833541c.-1T>C1.000
rpsA1833547c.6G>A1.000
rpsA1833589c.48A>C1.000
rpsA1833595c.54T>G1.000
rpsA1833596p.Ser19Ala1.000
rpsA1833616c.75A>C1.000
rpsA1833619c.78A>C1.000
rpsA1833661c.120A>G1.000
rpsA1833664c.123C>G1.000
rpsA1833667c.126C>G1.000
rpsA1833676c.135A>G1.000
rpsA1833679c.138G>T1.000
rpsA1833694c.153G>C1.000
rpsA1833697c.156C>G1.000
rpsA1833709c.168C>T1.000
rpsA1833724c.183C>G1.000
rpsA1833727c.186G>C1.000
rpsA1833734p.Ala65Ser1.000
rpsA1833770p.Asn77His1.000
rpsA1833778c.237C>G1.000
rpsA1833781c.240T>G1.000
rpsA1833793c.252C>T1.000
rpsA1833802c.261A>G1.000
rpsA1833811c.270G>C1.000
rpsA1833814c.273C>G1.000
rpsA1833820c.279G>A1.000
rpsA1833835c.294C>T1.000
rpsA1833838c.297G>T1.000
rpsA1833841c.300C>G1.000
rpsA1833847c.306C>G1.000
rpsA1833856c.315A>G1.000
rpsA1833862c.321G>C1.000
rpsA1833874c.333T>C1.000
rpsA1833886c.345C>G1.000
rpsA1833892c.351G>A1.000
rpsA1833894p.Ala118Glu1.000
rpsA1833928c.387G>C1.000
rpsA1833949c.408T>C1.000
rpsA1833970c.429G>C1.000
rpsA1833979c.438T>C1.000
rpsA1833988c.447C>G1.000
rpsA1833991c.450C>T0.988
rpsA1834015c.474G>C1.000
rpsA1834042c.501G>A1.000
rpsA1834051c.510G>A1.000
rpsA1834105c.564C>T1.000
rpsA1834150c.609G>C1.000
rpsA1834153c.612T>C1.000
rpsA1834154p.Asn205Gln1.000
rpsA1834157c.616T>C1.000
rpsA1834162c.621A>G1.000
rpsA1834165c.624A>G1.000
rpsA1834169p.Thr210Ala1.000
rpsA1834172p.Ile211Val1.000
rpsA1834177c.636A>C1.000
rpsA1834189c.648G>C1.000
rpsA1834213c.672G>A1.000
rpsA1834222c.681T>C1.000
rpsA1834225c.684C>G1.000
rpsA1834231c.690T>C0.986
rpsA1834240c.699T>C1.000
rpsA1834249c.708T>C1.000
rpsA1834261c.720A>G1.000
rpsA1834264c.723G>C1.000
rpsA1834294c.753G>C1.000
rpsA1834297c.756C>T1.000
rpsA1834303c.762T>G1.000
rpsA1834306c.765T>C1.000
rpsA1834348c.807T>C1.000
rpsA1834361c.820T>C1.000
rpsA1834366c.825A>G1.000
rpsA1834375c.834G>C1.000
rpsA1834396c.855G>C1.000
rpsA1834411c.870T>C1.000
rpsA1834423c.882G>T1.000
rpsA1834432c.891G>C1.000
rpsA1834451c.910T>C1.000
rpsA1834456c.915T>G1.000
rpsA1834468c.927A>G1.000
rpsA1834477c.936C>T1.000
rpsA1834489c.948T>C1.000
rpsA1834522c.981C>T1.000
rpsA1834527p.Arg329His1.000
rpsA1834540c.999G>C1.000
rpsA1834543c.1002C>G0.983
rpsA1834546c.1005T>C1.000
rpsA1834555c.1014T>C1.000
rpsA1834558c.1017C>G1.000
rpsA1834561c.1020C>T1.000
rpsA1834573c.1032G>C1.000
rpsA1834603p.Glu354Asp1.000
rpsA1834609c.1068T>C1.000
rpsA1834619c.1078T>C1.000
rpsA1834622c.1081T>A1.000
rpsA1834633c.1092A>G1.000
rpsA1834639c.1098T>C1.000
rpsA1834666c.1125G>C0.739
rpsA1834667p.Ala376Ser0.739
rpsA1834690c.1149T>C1.000
rpsA1834732c.1191T>C1.000
rpsA1834738c.1197A>G1.000
rpsA1834747c.1206A>G1.000
rpsA1834751p.Leu404Ile1.000
rpsA1834756c.1215G>A1.000
rpsA1834759c.1218A>T1.000
rpsA1834765p.Glu408Asp1.000
rpsA1834775p.Ala412Thr1.000
rpsA1834780c.1239A>G1.000
rpsA1834786c.1245A>G1.000
rpsA1834789c.1248T>C1.000
rpsA1834792c.1251G>C1.000
rpsA1834810c.1269C>T0.690
rpsA1834813c.1272G>T0.690
rpsA1834852c.1311C>T1.000
tlyA1918417c.478T>C1.000
tlyA1918422c.483T>C1.000
tlyA1918442p.Val168Ala1.000
tlyA1918446c.507A>C1.000
tlyA1918449c.510C>T1.000
tlyA1918452c.513T>G1.000
tlyA1918455c.516G>A1.000
tlyA1918457p.Arg173Pro1.000
tlyA1918473c.534T>G1.000
tlyA1918477p.Leu180Met1.000
pncA2289206c.36G>A1.000
pncA2289226p.Ile6Val1.000
pncA2289229p.Ile5Val1.000
pncA2289232c.10A>G1.000
pncA2289242c.-1T>C1.000
kasA2518219c.105T>C1.000
kasA2518220c.106C>T1.000
kasA2518223c.109T>C0.984
kasA2518231c.117C>T1.000
kasA2518243c.129C>T1.000
kasA2518248p.Ala45Val1.000
kasA2518269p.Thr52Ser1.000
kasA2518279c.165T>C1.000
kasA2518282c.168A>G1.000
kasA2518283p.Ala57Pro1.000
kasA2518300c.186T>C1.000
kasA2518304c.190C>T1.000
kasA2518322p.Ser70Asp1.000
kasA2518336c.222A>G1.000
kasA2518339c.225C>G1.000
kasA2518348c.234A>G1.000
kasA2518357c.243G>C1.000
kasA2518462c.348A>G1.000
kasA2518465c.351T>C1.000
kasA2518468c.354A>T1.000
kasA2518470p.Ala119Gly1.000
kasA2518480c.366T>C1.000
kasA2518488p.Ser125Thr1.000
kasA2518492c.378C>T1.000
kasA2518504c.390T>C1.000
kasA2518506p.Ala131Glu1.000
kasA2518513c.399C>A1.000
kasA2518519c.405G>C1.000
kasA2518528c.414C>G1.000
kasA2518564c.450C>G0.682
kasA2518567c.453G>C0.692
kasA2518574p.Ile154Val1.000
kasA2518588c.474T>C1.000
kasA2518591c.477G>C1.000
kasA2518594c.480C>T0.985
kasA2518606c.492G>C1.000
kasA2518609p.Met165Ile1.000
kasA2518636c.522C>T1.000
kasA2518642c.528A>G1.000
kasA2518648c.534C>T1.000
kasA2518651c.537C>A1.000
kasA2518672c.558G>C1.000
kasA2518684c.570C>G1.000
kasA2518688p.Val192Phe0.984
kasA2518693c.579C>G1.000
kasA2518714c.600A>C1.000
kasA2518715p.Pro201Gly1.000
kasA2518726c.612G>A1.000
kasA2518732c.618C>G1.000
kasA2518747c.633C>G1.000
kasA2518756c.642G>C1.000
kasA2518759c.645C>G1.000
kasA2518780p.Glu222Asp1.000
kasA2518783c.669T>C1.000
kasA2518787p.Arg225Gly1.000
kasA2518792c.678C>G1.000
kasA2518795c.681C>G1.000
kasA2518811p.Asp233Asn1.000
kasA2518816c.702C>G1.000
kasA2518825c.711T>C1.000
kasA2518828c.714G>C1.000
kasA2518834c.720C>T1.000
kasA2518837c.723G>A0.964
kasA2518843c.729T>C1.000
kasA2518853p.Leu247Ile1.000
kasA2518864c.750G>C1.000
kasA2518867c.753G>A1.000
kasA2518879c.765A>G1.000
kasA2518882c.768C>A1.000
kasA2518885c.771T>C1.000
kasA2518898c.784T>C1.000
kasA2518906c.792A>G1.000
kasA2518907c.793T>C1.000
kasA2518910p.Leu266Met1.000
kasA2518915c.801T>C1.000
kasA2518921c.807T>A1.000
kasA2518930c.816G>C1.000
ahpC2726564c.372C>G1.000
ahpC2726571p.Ala127Ser0.980
ahpC2726579c.387T>C1.000
ahpC2726582c.390G>C1.000
ahpC2726591c.399C>G1.000
ahpC2726593p.Val134Ala1.000
ahpC2726600c.408T>C1.000
ahpC2726604p.Val138Ile1.000
ahpC2726624c.432C>T1.000
ahpC2726638p.Ala149Val1.000
ahpC2726642c.450C>G0.967
ahpC2726645c.453C>G0.984
ahpC2726657c.465A>C0.983
ahpC2726669c.477T>C1.000
ahpC2726675c.483A>G1.000
ahpC2726681c.489A>G1.000
ahpC2726687c.495C>G1.000
ahpC2726696c.504C>G1.000
ahpC2726717c.525A>C1.000
folC2746534c.1065A>G1.000
folC2746566p.Ala345Ser0.975
folC2746576c.1023G>C1.000
folC2746584c.1015A>G1.000
folC2746702c.897C>G1.000
folC2746714c.885A>G1.000
folC2746948c.651C>G1.000
folC2746958p.Gly214Glu1.000
folC2746975c.624A>G1.000
folC2746979p.Ala207Glu1.000
folC2746987c.612A>G1.000
folC2746999c.600A>G1.000
folC2747002c.597A>G1.000
folC2747007p.Ser198Gly1.000
folC2747011c.588C>G1.000
folC2747032c.567T>A1.000
folC2747037p.Asn188Glu1.000
folC2747040p.Ile187Val1.000
folC2747041c.558C>G1.000
folC2747059c.540A>G1.000
folC2747062c.537T>A1.000
folC2747065c.534G>A1.000
folC2747074c.525C>G1.000
folC2747077c.522C>T1.000
folC2747080c.519G>C1.000
folC2747085p.Val172Ile1.000
folC2747086c.513T>G1.000
folC2747089c.510C>G1.000
folC2747098c.501G>C1.000
folC2747101c.498C>G1.000
folC2747107c.492C>G1.000
folC2747110c.489A>G1.000
folC2747113c.486G>T0.950
folC2747129p.Ala157Gly1.000
folC2747155c.444C>G1.000
thyX3067223c.723C>G1.000
thyX3067226c.720C>T1.000
thyX3067244c.702G>C1.000
thyX3067248p.Thr233Ser1.000
thyX3067252p.Val232Ile1.000
thyX3067255p.Glu231Gln1.000
thyX3067263p.Ala228Gly1.000
thyX3067269p.Val226Ala1.000
thyX3067274c.672G>C0.789
thyX3067277c.669G>A0.810
thyX3067284p.Ala221Asp0.897
thyX3067295c.651G>T1.000
thyX3067304c.642T>C1.000
thyX3067309p.Ile213Val1.000
thyX3067316c.630T>C1.000
thyX3067319c.627C>G1.000
thyX3067322c.624G>A1.000
thyX3067325c.621T>C1.000
thyX3067328c.618C>G1.000
thyX3067331c.615G>A1.000
thyX3067355c.591T>C1.000
thyX3067373c.573G>T1.000
thyX3067382c.564G>A1.000
thyX3067388c.558G>C1.000
thyX3067402p.Arg182Cys1.000
thyX3067403c.543G>C1.000
thyX3067406c.540T>C1.000
thyX3067427c.519C>G1.000
thyX3067430c.516G>A1.000
thyX3067457c.489G>C1.000
thyX3067595c.351G>T1.000
thyX3067612p.Lys112Pro1.000
thyX3067613c.333C>T1.000
thyX3067619c.327T>C1.000
thyX3067622c.324G>A1.000
thyX3067634c.312G>C1.000
thyX3067640c.306C>G1.000
thyX3067644p.Tyr101Phe1.000
thyX3067646c.300G>C1.000
thyX3067652c.294A>G1.000
thyX3067661c.285G>C1.000
thyX3067667c.279C>G1.000
thyX3067727c.219T>G1.000
thyX3067739c.207A>G1.000
thyX3067742c.204T>C1.000
thyX3067762p.Arg62Lys1.000
thyX3067763c.183G>C1.000
thyX3067771p.Gly59Thr1.000
thyX3067781c.165G>C1.000
thyX3067789p.Lys53Arg1.000
thyX3067790c.156G>C1.000
thyX3067793c.153A>G1.000
thyX3067799c.147C>T1.000
thyX3067817c.129G>A1.000
thyX3067844c.102C>T1.000
thyX3067849p.Pro33Ser1.000
thyX3067850c.96T>C1.000
thyX3067869p.Thr26Ser1.000
thyX3067874c.72G>C1.000
thyX3067877c.69C>T1.000
thyX3067883c.63G>C1.000
thyX3067886c.60T>C1.000
thyX3067891p.Ala19Pro1.000
thyX3067894p.Leu18Ser1.000
thyX3067898p.Asp16Glu1.000
thyX3067910c.36G>A1.000
thyX3067934c.12G>C1.000
thyX3067949c.-4C>T1.000
thyA3073863c.609A>G1.000
thyA3073881c.591G>C1.000
thyA3073889p.Ser195Gly1.000
thyA3073892c.580A>G1.000
thyA3073893c.579G>C1.000
thyA3073902c.570G>C1.000
thyA3073920c.552G>C1.000
thyA3073925c.547A>G1.000
thyA3073953c.519A>G1.000
thyA3073956c.516C>G1.000
thyA3073959c.513A>G1.000
thyA3073965c.507G>A1.000
thyA3073977c.495T>C1.000
thyA3073989c.483A>G1.000
thyA3073994c.478C>G1.000
thyA3074000p.Arg158Lys0.962
thyA3074004c.468A>G0.964
thyA3074027p.Phe149Leu1.000
thyA3074031c.441A>G1.000
thyA3074042p.Pro144Ala1.000
thyA3074061c.411T>C1.000
thyA3074076c.396G>T0.974
thyA3074082c.390C>G1.000
thyA3074091c.381G>C1.000
thyA3074094c.378C>G1.000
thyA3074103c.369G>C0.920
thyA3074106c.366A>G1.000
thyA3074229c.243G>A1.000
thyA3074235c.237G>A1.000
thyA3074244c.228T>A1.000
thyA3074250c.222C>T1.000
thyA3074255p.His73Asn1.000
thyA3074256c.216C>G1.000
thyA3074263p.Gly70Ala1.000
thyA3074268c.204A>G1.000
thyA3074274c.198A>G1.000
thyA3074285c.187A>G1.000
thyA3074305p.Ala56Val1.000
thyA3074307c.165T>C1.000
thyA3074313c.159T>C1.000
thyA3074318p.Phe52Leu1.000
thyA3074319c.153A>G1.000
thyA3074322c.150G>C1.000
thyA3074325c.147T>C1.000
thyA3074334c.138A>G1.000
thyA3074339p.Leu45Ile0.957
thyA3074349c.123A>T1.000
thyA3074357p.Ser39Ala1.000
thyA3074360c.112A>G1.000
thyA3074361c.111A>G1.000
thyA3074372p.Met34Leu1.000
thyA3074376p.Gln32His1.000
thyA3074397c.75T>G1.000
ald3087728c.910 911insCGG1.000
fbiA3640318c.-225A>G1.000
fbiA3640319c.-224A>T1.000
fbiA3640350c.-193C>T1.000
fbiA3640355c.-188C>T0.986
fbiA3640365c.-178C>G1.000
fbiA3640377c.-166G>A1.000
fbiA3640378c.-165A>G1.000
fbiA3641046c.504T>C1.000
fbiA3641049c.507T>C1.000
fbiA3641274c.732G>C1.000
fbiA3641285p.Gly248Ala1.000
fbiA3641288p.Glu249Gly1.000
embC4240435c.573C>T1.000
embC4240462c.600G>C0.636
embC4240464p.Phe201Tyr0.636
embC4240475p.Ala205Ser0.864
embC4240480c.618G>C1.000
embC4240632p.Met257Thr1.000
embC4240645c.783G>C1.000
embC4240654c.792C>G1.000
embC4240657c.795G>C1.000
embC4240670p.Thr270Ala1.000
embC4240674p.Gly271Ala1.000
embC4240677p.Gly272Ala1.000
embC4240683p.Asp274Val1.000
embC4240702c.840G>C1.000
embC4240708c.846G>C1.000
embC4240717c.855T>C1.000
embC4240726c.864G>C1.000
embC4240736c.874T>A0.969
embC4240765c.903C>G1.000
embC4240769p.Val303Ile1.000
embC4240780c.918T>C1.000
embC4240783c.921G>C1.000
embC4240789c.927T>C1.000
embC4240800p.Tyr313Phe1.000
embC4240819c.957A>C1.000
embC4240831c.969T>G1.000
embC4240855c.993G>C1.000
embC4240859p.Leu333Val1.000
embC4240865p.Ala335Ser0.235
embC4240869p.His336Arg1.000
embC4240879c.1017G>C1.000
embC4240880p.Ala340Ser1.000
embC4240885c.1023T>C1.000
embC4240888c.1026C>T1.000
embC4240897c.1035C>G1.000
embC4240900c.1038A>G1.000
embC4240912c.1050G>T1.000
embC4240921c.1059C>G1.000
embC4240922p.Thr354Ala1.000
embC4240934p.Val358Leu1.000
embC4240951c.1089C>G1.000
embC4240954c.1092T>C1.000
embC4240957c.1095C>G1.000
embC4240960c.1098G>C1.000
embC4240963c.1101G>A1.000
embC4240966c.1104G>C1.000
embC4240979p.Thr373His1.000
embC4240990c.1128A>G1.000
embC4240996c.1134G>C1.000
embC4241008c.1146G>C1.000
embC4241017c.1155T>C1.000
embC4241023c.1161T>G1.000
embC4241024p.Val388Phe1.000
embC4241039p.Asp393Asn1.000
embC4241050c.1188T>G1.000
embC4241053c.1191G>T1.000
embC4241071c.1209C>G1.000
embC4241084p.Leu408Ala1.000
embC4241125c.1263G>A1.000
embC4241135p.Val425Leu1.000
embC4241140c.1278A>G1.000
embC4241158c.1296T>C1.000
embC4241161c.1299C>A1.000
embC4241162p.Leu434Met1.000
embC4241167c.1305C>G1.000
embC4241168c.1306C>T0.960
embC4241185c.1323G>C1.000
embC4241188c.1326C>G1.000
embC4241194c.1332C>G1.000
embC4241215c.1353C>G1.000
embC4241224c.1362G>T0.977
embC4241230c.1368A>G1.000
embC4241233c.1371G>C1.000
embC4241240c.1378C>T1.000
embC4241404p.Asp514Glu1.000
embC4241407c.1545A>G1.000
embC4241411p.Ile517Val1.000
embC4241432p.Met524Leu1.000
embC4241439p.Ser526Thr1.000
embC4241453p.Ile531Val1.000
embC4241458c.1596C>G0.944
embC4241464c.1602C>G1.000
embC4241468p.Ala536Pro1.000
embC4241479c.1617C>G1.000
embC4241484p.Val541Gly1.000
embC4241488c.1626G>C1.000
embC4241494c.1632C>G1.000
embC4241500c.1638A>G1.000
embC4241509c.1647A>G0.929
embC4241513p.Ser551Ala1.000
embC4241518c.1656A>G1.000
embC4241521c.1659T>C1.000
embC4241530c.1668C>G1.000
embC4241536c.1674A>T1.000
embC4241539c.1677T>C1.000
embC4241542c.1680C>G1.000
embC4241545c.1683T>G1.000
embC4241548c.1686T>C1.000
embC4241560c.1698C>G1.000
embC4241572c.1710C>G1.000
embC4241578c.1716G>C1.000
embC4241584c.1722T>C1.000
embC4241587c.1725C>G1.000
embC4241591p.Leu577Ile1.000
embC4241597p.Met579Leu1.000
embC4241608c.1746C>G1.000
embC4241611c.1749G>C1.000
embC4241614c.1752A>C1.000
embC4241623c.1761C>G1.000
embC4241632c.1770C>T1.000
embC4241635c.1773G>T1.000
embC4241644c.1782G>C1.000
embC4241648c.1786T>C1.000
embC4241656c.1794G>T1.000
embC4241660p.Leu600Val1.000
embC4241671c.1809T>G1.000
embC4241677c.1815G>C1.000
embC4241770c.1908T>C1.000
embC4241803c.1941T>C1.000
embC4241809c.1947A>G1.000
embC4242376c.2514G>C1.000
embC4242382c.2520C>T1.000
embC4242388p.Asn842Lys1.000
embC4242403c.2541T>G1.000
embC4242404p.Thr848Val1.000
embC4242907c.3045G>T1.000
embC4242919c.3057A>G1.000
embC4242922c.3060C>G1.000
embC4242928c.3066A>T1.000
embC4242940c.3078T>C1.000
embC4242941p.His1027Asn0.958
embC4242946c.3084T>C1.000
embC4242949c.3087C>T1.000
embC4242958c.3096G>C1.000
embC4242977c.3115C>T1.000
embC4242980p.Met1040Val1.000
embC4242988c.3126A>G1.000
embA4244195c.963C>G1.000
embA4244198c.966C>G1.000
embA4244219c.987C>G1.000
embA4244228c.996A>T1.000
embA4244229p.Ile333Val1.000
embA4244247p.Val339Ile1.000
embA4244355p.Phe375Leu0.255
embA4244372c.1140T>C0.760
embA4244382p.Leu384Ile0.149
embA4244593p.Ala454Val0.788
embA4244657c.1425G>C1.000
embA4244664p.Thr478Ala1.000
embA4244669c.1437G>C1.000
embA4244681c.1449A>C1.000
embA4244694p.Lys488Val1.000
embA4244702c.1470C>T1.000
embA4244726p.Asp498Glu1.000
embA4244735c.1503C>G1.000
embA4244747c.1515T>G1.000
embA4244753c.1521G>C0.174
embA4244754p.Glu508Lys0.905
embA4244765c.1533T>C1.000
embA4244768p.Glu512Asp1.000
embA4244770p.Gly513Ala1.000
embA4244774c.1542G>A1.000
embA4244775p.Met515Leu1.000
embA4244778p.Ser516Thr1.000
embA4244802c.1570T>C1.000
embA4244814p.Leu528Met1.000
embA4244821p.Gly530Ala1.000
embA4244823p.Val531Met1.000
embA4244829p.Phe533Val1.000
embA4244843c.1611G>A1.000
embA4244853p.Val541Ile1.000
embA4244856p.Ala542Asn1.000
embA4244862p.Leu544Val1.000
embA4244885c.1653A>G1.000
embA4244894c.1662C>A1.000
embA4244895p.Thr555Ser1.000
embA4244900c.1668G>C1.000
embA4244906c.1674C>G1.000
embA4244909c.1677C>T1.000
embA4244919c.1687C>T1.000
embA4244930c.1698G>C1.000
embA4244933c.1701A>G1.000
embA4244945c.1713C>G1.000
embA4244959p.Ala576Gly1.000
embA4244980p.Val583Ala1.000
embA4244982c.1750T>C1.000
embA4244986p.Gly585Ala1.000
embA4244991p.Val587Leu1.000
embA4245008c.1776T>C1.000
embA4245434c.2202G>C1.000
embA4245455c.2223C>A0.402
embA4245458c.2226G>A0.402
embA4245465p.Pro745Val1.000
embA4245477p.Met749Leu0.485
embB4247050c.537C>G1.000
embB4247068c.555T>C1.000
embB4247090p.Thr193Ala1.000
embB4247095c.582G>T1.000
embB4247401c.888T>C1.000
embB4247404c.891G>C1.000
embB4247407c.894G>C1.000
embB4247428c.915C>G1.000
embB4247437c.924A>G1.000
embB4247446c.933C>T0.983
embB4247462c.949T>A1.000
embB4247470c.957T>C1.000
embB4247476c.963C>G1.000
embB4247488c.975C>T1.000
embB4247494c.981G>A1.000
embB4247497c.984T>C1.000
embB4247500c.987C>G1.000
embB4247512c.999T>C1.000
embB4247536c.1023C>G1.000
embB4247539c.1026T>C1.000
embB4247543c.1030A>T1.000
embB4247554c.1041T>C1.000
embB4247555p.Leu348Ile0.960
embB4247563p.Met350Ile1.000
embB4247566c.1053C>G1.000
embB4247572c.1059A>G1.000
embB4247576c.1063C>T1.000
embB4247584c.1071C>G1.000
embB4247590c.1077A>G1.000
embB4247609c.1096T>A1.000
embB4247614c.1101T>C0.674
embB4247629c.1116C>A0.708
embB4247630p.Leu373Phe1.000
embB4247635c.1122G>C1.000
embB4247646p.Glu378Ala1.000
embB4247656c.1143A>G1.000
embB4247663p.Tyr384Leu1.000
embB4247674c.1161G>C1.000
embB4247678p.Met389Leu1.000
embB4247683c.1170C>G1.000
embB4247684c.1171T>C1.000
embB4247690p.Thr393Ala1.000
embB4247722c.1209G>C1.000
embB4247725c.1212G>C1.000
embB4247857c.1344C>G1.000
embB4247866c.1353G>A1.000
embB4247879p.Val456Leu1.000
embB4247893c.1380C>T1.000
embB4247897p.Met462Leu1.000
embB4248041p.Ala510Thr1.000
embB4248044p.Lys511Ala1.000
embB4248052c.1539G>C1.000
embB4248064c.1551G>C1.000
embB4248070c.1557T>C1.000
embB4248076c.1563G>A1.000
embB4248085c.1572T>C1.000
embB4248097c.1584C>G1.000
embB4248106c.1593C>G1.000
embB4248118c.1605T>G1.000
embB4248121c.1608G>A1.000
embB4248133c.1620C>G1.000
embB4248139c.1626C>T1.000
embB4248142c.1629T>C1.000
embB4248143c.1630T>C1.000
embB4248149p.Thr546Cys1.000
embB4248157c.1644A>G1.000
embB4248173p.Val554Met1.000
embB4248199c.1686A>T1.000
embB4248200p.Ile563Val1.000
embB4248206p.Ser565Gly1.000
embB4248211c.1698G>C1.000
embB4248215p.Arg568Ser0.976
embB4248220c.1707A>C1.000
embB4248225p.Ala571Val1.000
embB4248248p.Phe579Leu1.000
embB4248252p.Gly580Ala1.000
embB4248264p.Phe584Ser1.000
embB4248275p.Thr588Ala0.554
embB4248432p.Trp640Phe1.000
embB4248457c.1944T>C1.000
embB4248463c.1950C>G1.000
embB4248469c.1956C>T1.000
embB4248472c.1959T>C1.000
embB4248742c.2229T>C1.000
embB4248745c.2232C>G1.000
embB4248757c.2244A>G1.000
embB4248940c.2427C>G1.000
embB4249138c.2625C>G1.000
embB4249140p.Val876Ala1.000
embB4249158p.Lys882Thr1.000
embB4249483c.2970C>G0.978
embB4249486c.2973T>C1.000
embB4249487c.2974T>C1.000
embB4249507p.Gln998His1.000
ethA4326587p.Val296Ala1.000
ethA4326598c.876T>C1.000
ethA4326603p.Gln291Glu1.000
ethA4326610c.864G>C1.000
ethA4326620p.His285Arg1.000
ethA4326625c.849G>C1.000
ethA4327033c.441G>A1.000
ethA4327043p.Asp144Ala1.000
ethA4327388p.Thr29Asn1.000
ethA4327396c.78A>G1.000
ethA4327425p.Val17Ile1.000
ethA4327435c.39T>G1.000
ethA4327438c.36A>G1.000
ethA4327444c.30C>G1.000
ethA4327450c.24G>C1.000
ethA4327456c.18G>A1.000
ethA4327465c.9C>T1.000
ethA4327468c.6G>A1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;