TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5cd41cf398ffc
Sample: 5cd41cf398ffc

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Summary
ID: 5cd41cf398ffc
Date: Thu May 9 13:30:38 2019
Strain: lineage4.6;lineage4.3
Drug-resistance: Drug-resistant

Drug1ResistanceSupporting Mutations (frequency)
IsoniazidRkatG p.Ile335Thr (0.46), katG p.Ile317Leu (0.50), katG p.Ser315Thr (0.50)
Rifampicin
EthambutolRembB p.His312Arg (0.49), embB p.Leu359Ile (0.44), embB p.Tyr384Asn (0.38), embB p.Ala388Gly (0.52), embB p.Asn399Asp (0.53), embB p.Ala659Thr (0.73)
PyrazinamideRpanD p.Val138Ala (0.68)
StreptomycinRrrs r.462c>t (0.52)
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage4.6Euro-AmericanT;LAMNone
lineage4.3Euro-American (LAM)mainly-LAMNone

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5230c.-10T>C0.278
gyrB5235c.-5G>C0.294
gyrB5238c.-2T>C0.294
gyrB5254c.15A>G0.278
gyrB5263c.24C>G0.294
gyrB5272p.Glu11Asp0.263
gyrB5282p.Ala15Ser0.211
gyrB5285p.Ser16Ala0.238
gyrB5294p.Ile19Val0.238
gyrB5305c.66G>C0.227
gyrB5308c.69G>C0.227
gyrB5311c.72G>A0.227
gyrB5326c.87T>C0.227
gyrB5341c.102T>C0.231
gyrB5344c.105C>G0.231
gyrB5347c.108G>C0.240
gyrB5353c.114T>C0.250
gyrB5359c.120C>T0.261
gyrB5363c.124T>C0.370
gyrB5371c.132T>C0.444
gyrB5377c.138T>C0.464
gyrB5396p.Ala53Ser0.500
gyrB5419c.180T>C0.533
gyrB5614c.375G>C0.400
gyrB5623c.384T>C0.364
gyrB5632c.393A>G0.364
gyrB5635c.396C>G0.364
gyrB5772p.Ala178Asp0.516
gyrB5774p.Val179Ile0.516
gyrB5782c.543A>G0.531
gyrB5788c.549G>C0.531
gyrB5791c.552A>G0.531
gyrB5803c.564A>G0.548
gyrB5806c.567C>G0.531
gyrB5809c.570C>G0.531
gyrB5812c.573C>G0.531
gyrB5824c.585A>G0.548
gyrB5827c.588G>A0.562
gyrB5849c.610C>T0.562
gyrB5863c.624G>C0.600
gyrB5873c.634A>C0.607
gyrB6013c.774G>C0.636
gyrB6022c.783G>C0.636
gyrB6025c.786A>G0.636
gyrB6082c.843G>A0.700
gyrB6086p.Thr283Pro0.727
gyrB6091c.852G>C0.727
gyrB6100c.861G>C0.727
gyrB6115c.876A>G0.792
gyrB6123p.Ala295Gly0.792
gyrB6127c.888G>C0.792
gyrB6130c.891T>C0.792
gyrB6136c.897G>A0.792
gyrB6139c.900G>C0.792
gyrB6196c.957C>T0.758
gyrB6238c.999G>A0.719
gyrB6242p.Arg335Lys0.786
gyrB6250c.1011A>G0.686
gyrB6256c.1017G>A0.686
gyrB6268c.1029C>G0.711
gyrB6280c.1041T>C0.703
gyrB6286c.1047T>C0.694
gyrB6289c.1050C>T0.667
gyrB6292c.1053G>C0.676
gyrB6307c.1068T>G0.710
gyrB6319c.1080G>C0.679
gyrB6362c.1123T>C0.739
gyrB6376c.1137G>A0.571
gyrB6379c.1140C>G0.571
gyrB6382c.1143A>G0.571
gyrB6388c.1149T>C0.571
gyrB6403c.1164T>C0.520
gyrB6415c.1176G>C0.591
gyrB6427c.1188T>C0.591
gyrB6430c.1191A>G0.591
gyrB6440p.Thr401Ala0.444
gyrB6448c.1209G>C0.421
gyrB6451c.1212A>G0.421
gyrB6454c.1215C>G0.421
gyrB6457c.1218T>G0.421
gyrB6460c.1221G>C0.421
gyrB6469c.1230T>G0.455
gyrB6475c.1236C>G0.435
gyrB6484c.1245A>G0.550
gyrB6490c.1251T>G0.550
gyrB6496c.1257G>C0.524
gyrB6499c.1260A>G0.524
gyrB6502c.1263T>C0.545
gyrB6508c.1269A>G0.565
gyrB6523c.1284G>T0.542
gyrB6526c.1287T>C0.542
gyrB6541c.1302C>T0.500
gyrB6542p.Ile435Leu0.500
gyrB6547c.1308T>C0.500
gyrB6550c.1311A>G0.500
gyrB6551c.1312T>C0.500
gyrB6565c.1326G>C0.522
gyrB6571c.1332T>C0.500
gyrB6577c.1338T>C0.500
gyrB6580c.1341C>G0.500
gyrB6598c.1359C>G0.480
gyrB6610c.1371C>G0.500
gyrB6613c.1374A>G0.480
gyrB6616c.1377A>G0.500
gyrB6622c.1383C>T0.556
gyrB6634c.1395T>C0.520
gyrB6637c.1398T>G0.542
gyrB6640c.1401A>G0.577
gyrB6643c.1404A>G0.577
gyrB6649c.1410T>C0.607
gyrB6655c.1416T>C0.630
gyrB6670c.1431G>C0.594
gyrB6673c.1434A>C0.625
gyrB6676c.1437T>G0.625
gyrB6700c.1461T>C0.667
gyrB6703c.1464G>C0.667
gyrB6709c.1470A>G0.690
gyrB6712c.1473G>C0.690
gyrB6728c.1489C>T0.742
gyrB6742c.1503A>G0.741
gyrB6745c.1506T>G0.750
gyrB6751c.1512G>C0.759
gyrB6760c.1521G>C0.731
gyrB6763c.1524G>C0.731
gyrB6775c.1536G>C0.679
gyrB6793c.1554T>C0.655
gyrB6797p.Gly520Thr0.655
gyrB6811c.1572C>T0.633
gyrB6841c.1602T>C0.625
gyrB6844c.1605T>C0.625
gyrB6853c.1614A>G0.571
gyrB6856c.1617T>C0.577
gyrB6859c.1620T>C0.577
gyrB6862c.1623C>G0.600
gyrB6868c.1629G>C0.556
gyrB6877c.1638G>T0.520
gyrB6878c.1639T>C0.520
gyrB6881c.1642T>C0.520
gyrB6889c.1650G>T0.630
gyrB6901c.1662G>C0.630
gyrB6904c.1665C>G0.630
gyrB6910c.1671G>A0.630
gyrB6919c.1680T>C0.667
gyrB6925c.1686T>C0.667
gyrB6931c.1692A>G0.630
gyrB6949c.1710A>G0.674
gyrB6952c.1713C>G0.667
gyrB6967c.1728T>C0.659
gyrB6973c.1734G>C0.659
gyrB6982c.1743A>C0.651
gyrB7006c.1767T>C0.645
gyrB7007c.1768C>T0.645
gyrB7010c.1771C>T0.645
gyrB7015c.1776G>A0.645
gyrB7018c.1779G>A0.645
gyrB7023p.Leu595Gln0.645
gyrB7033c.1794G>C0.676
gyrB7051p.Glu604Asp0.686
gyrB7066c.1827G>C0.647
gyrB7075c.1836T>C0.615
gyrB7078c.1839A>C0.615
gyrB7084c.1845A>G0.600
gyrB7090c.1851C>T0.652
gyrB7093c.1854T>G0.652
gyrB7099c.1860G>A0.619
gyrB7102c.1863G>A0.650
gyrB7108c.1869G>A0.650
gyrB7114c.1875C>A0.696
gyrB7124p.Ser629Thr0.650
gyrB7129c.1890T>C0.632
gyrB7132c.1893T>G0.632
gyrB7141c.1902T>C0.690
gyrB7147c.1908G>C0.706
gyrB7165c.1926C>G0.714
gyrB7178c.1939T>C0.706
gyrB7186c.1947C>G0.703
gyrB7216c.1977G>C0.676
gyrB7234c.1995C>T0.632
gyrB7246c.2007T>C0.632
gyrB7252c.2013G>C0.611
gyrB7256c.2017C>T0.611
gyrA7301c.-1G>C0.613
gyrA7307c.6A>T0.690
gyrA7313c.12G>C0.719
gyrA7317c.16T>C0.742
gyrA7334c.33G>C0.722
gyrA7335p.Leu12Val0.722
gyrA7347p.Glu16Gln0.730
gyrA7361c.60C>T0.711
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T0.650
gyrA7394c.93T>C0.650
gyrA7427c.126G>C0.667
gyrA7442c.141G>C0.615
gyrA7451c.150C>G0.623
gyrA7457c.156T>C0.627
gyrA7475c.174A>G0.593
gyrA7480p.Phe60Tyr0.577
gyrA7484c.183T>C0.558
gyrA7490c.189C>G0.607
gyrA7523c.222C>G0.576
gyrA7532c.231T>G0.554
gyrA7541c.240C>G0.528
gyrA7547c.246C>T0.577
gyrA7571c.270G>C0.565
gyrA7585p.Ser95Thr1.000
gyrA7595c.294C>G0.605
gyrA7601c.300C>G0.643
gyrA7607c.306C>T0.667
gyrA7622c.321C>T0.675
gyrA7625c.324G>C0.667
gyrA7631c.330G>C0.700
gyrA7637c.336C>G0.784
gyrA7652c.351C>T0.829
gyrA7658c.357A>C0.818
gyrA7664c.363T>C0.818
gyrA7670c.369A>G0.788
gyrA7679c.378G>C0.774
gyrA7685c.384G>A0.767
gyrA7688c.387C>T0.759
gyrA7694c.393A>G0.808
gyrA7697c.396C>G0.808
gyrA7710c.409T>C0.762
gyrA7715c.414G>C0.762
gyrA7721c.420G>A0.800
gyrA7725c.424C>T0.800
gyrA7728c.427A>C0.800
gyrA7763c.462T>C0.763
gyrA7775c.474C>A0.718
gyrA7781c.480G>C0.744
gyrA7784c.483A>G0.744
gyrA7790c.489G>C0.730
gyrA7793c.492G>C0.730
gyrA7796c.495G>C0.711
gyrA7799c.498A>G0.707
gyrA7814c.513C>G0.711
gyrA7823c.522G>C0.721
gyrA7832c.531G>T0.698
gyrA7835c.534A>C0.698
gyrA7853c.552C>G0.578
gyrA7859c.558A>G0.658
gyrA7865c.564T>C0.667
gyrA7886c.585T>C0.647
gyrA8069c.768T>C0.579
gyrA8078c.777A>G0.575
gyrA8090c.789C>A0.575
gyrA8093c.792C>T0.575
gyrA8096c.795T>A0.575
gyrA8099c.798T>C0.575
gyrA8111c.810G>C0.605
gyrA8121c.820T>C0.537
gyrA8129c.828T>C0.524
gyrA8135c.834C>G0.500
gyrA8156c.855T>C0.457
gyrA8168c.867A>G0.364
gyrA8177c.876A>C0.364
gyrA8198c.897T>C0.560
gyrA8207c.906T>C0.560
gyrA8219c.918T>C0.558
gyrA8225c.924T>C0.571
gyrA8234c.933T>C0.535
gyrA8237c.936A>G0.535
gyrA8247p.Ile316Val0.535
gyrA8264c.963T>C0.524
gyrA8267c.966G>C0.524
gyrA8270c.969G>C0.512
gyrA8276c.975G>A0.523
gyrA8283p.Ile328Leu0.575
gyrA8288c.987T>C0.575
gyrA8294c.993T>C0.646
gyrA8324c.1023T>C0.714
gyrA8330c.1029C>G0.708
gyrA8339c.1038A>G0.696
gyrA8340p.Ala347Ser0.696
gyrA8372c.1071G>C0.744
gyrA8375c.1074G>C0.732
gyrA8382p.Leu361Met0.714
gyrA8387c.1086C>T0.714
gyrA8391p.Tyr364His0.732
gyrA8399c.1098T>G0.744
gyrA8401p.Asp367Ala0.725
gyrA8405c.1104C>T0.732
gyrA8420c.1119T>C0.740
gyrA8442c.1141C>T0.717
gyrA8453c.1152A>C0.738
gyrA8459c.1158G>A0.732
gyrA8462c.1161A>T0.725
gyrA8465c.1164C>G0.690
gyrA8471c.1170T>C0.707
gyrA8472c.1171C>T0.707
gyrA8480c.1179C>A0.756
gyrA8486c.1185T>C0.775
gyrA8504c.1203G>C0.786
gyrA8516c.1215T>C0.757
gyrA8519c.1218A>C0.737
gyrA8520c.1219C>T0.737
gyrA8528c.1227G>C0.725
gyrA8543c.1242C>G0.676
gyrA8546c.1245T>C0.667
gyrA8552c.1251C>A0.676
gyrA8561c.1260A>G0.686
gyrA8576c.1275C>G0.686
gyrA8579c.1278C>T0.686
gyrA8588c.1287G>A0.694
gyrA8597c.1296C>G0.676
gyrA8603c.1302A>G0.667
gyrA8619c.1318T>C0.688
gyrA8624c.1323G>C0.535
gyrA8636c.1335A>C0.571
gyrA8642c.1341A>G0.725
gyrA8672c.1371A>G0.743
gyrA8678c.1377G>A0.735
gyrA8693c.1392T>C0.714
gyrA8696c.1395G>C0.714
gyrA8699c.1398A>G0.707
gyrA8711c.1410A>C0.732
gyrA8714c.1413A>G0.711
gyrA8729c.1428T>C0.659
gyrA8730p.Gly477Arg0.659
gyrA8740p.Arg480His0.632
gyrA8747c.1446A>G0.600
gyrA8750c.1449C>G0.600
gyrA8751p.Ala484Ser0.600
gyrA8756c.1455A>G0.600
gyrA8762c.1461G>C0.600
gyrA8767p.Arg489Lys0.600
gyrA8780p.Asp493Glu0.650
gyrA8786c.1485T>C0.650
gyrA8801c.1500G>C0.634
gyrA8807c.1506C>T0.571
gyrA8810c.1509A>G0.550
gyrA8816c.1515C>G0.568
gyrA8818p.Ser506Asn0.568
gyrA8828c.1527T>C0.610
gyrA8837c.1536C>T0.615
gyrA8852c.1551T>C0.590
gyrA8858c.1557T>C0.590
gyrA8867c.1566A>G0.550
gyrA8870c.1569G>C0.526
gyrA8873c.1572A>C0.500
gyrA8891c.1590G>A0.571
gyrA8897c.1596T>C0.588
gyrA8903c.1602T>C0.600
gyrA8933c.1632G>C0.500
gyrA8939c.1638T>C0.436
gyrA8942c.1641G>C0.447
gyrA8946c.1645T>C0.425
gyrA8966c.1665C>G0.452
gyrA8967p.Ala556Arg0.452
gyrA8987c.1686C>G0.436
gyrA8990c.1689C>G0.436
gyrA8996c.1695T>C0.439
gyrA8998p.Leu566Trp0.439
gyrA9017c.1716C>G0.526
gyrA9023c.1722A>C0.526
gyrA9029c.1728T>C0.514
gyrA9032c.1731T>C0.514
gyrA9035c.1734G>C0.526
gyrA9050p.Asp583Glu0.605
gyrA9051c.1750T>C0.667
gyrA9056c.1755C>G0.727
gyrA9062c.1761C>G0.714
gyrA9068c.1767G>C0.714
gyrA9071c.1770G>C0.706
gyrA9080c.1779G>T0.792
gyrA9089c.1788G>C0.816
gyrA9099c.1798T>C0.854
gyrA9104c.1803C>G0.812
gyrA9119c.1818A>G0.812
gyrA9122c.1821C>G0.812
gyrA9143c.1842T>C0.800
gyrA9152c.1851C>T0.778
gyrA9153p.Thr618Glu0.778
gyrA9158c.1857C>T0.795
gyrA9161c.1860C>G0.778
gyrA9182c.1881T>C0.860
gyrA9191c.1890G>C0.860
gyrA9200c.1899A>G0.857
gyrA9204p.Ser635Thr0.860
gyrA9224c.1923C>T0.852
gyrA9230c.1929T>C0.836
gyrA9233c.1932C>G0.839
gyrA9239c.1938C>T0.839
gyrA9252p.Val651Ile0.778
gyrA9284c.1983T>C0.741
gyrA9291c.1990C>T0.696
gyrA9296c.1995T>C0.705
gyrA9299c.1998G>C0.683
gyrA9300p.Ala667Ser0.683
gyrA9304p.Gly668Asp1.000
gyrA9308p.Asp669Glu0.683
gyrA9323c.2022C>G0.681
gyrA9335c.2034G>C0.659
gyrA9365c.2064G>A0.658
gyrA9374c.2073G>C0.658
gyrA9377c.2076A>G0.658
gyrA9383c.2082T>G0.667
gyrA9386c.2085T>C0.657
gyrA9395c.2094G>C0.719
gyrA9398c.2097T>C0.657
gyrA9413c.2112G>C0.553
gyrA9518c.2217A>G0.280
gyrA9521c.2220C>T0.280
gyrA9527c.2226A>G0.241
gyrA9533c.2232C>T0.259
gyrA9542c.2241T>C0.280
gyrA9545c.2244A>G0.280
gyrA9548c.2247T>C0.269
gyrA9551c.2250G>C0.269
gyrA9552c.2251C>T0.292
gyrA9560c.2259C>G0.400
gyrA9566c.2265C>T0.400
gyrA9572c.2271C>T0.455
gyrA9584c.2283G>A0.455
gyrA9585c.2284T>C0.455
gyrA9590c.2289T>C0.455
gyrA9593c.2292G>C0.455
gyrA9602c.2301T>C0.478
gyrA9611p.Asp770Glu0.455
gyrA9626c.2325T>C0.429
gyrA9629c.2328C>G0.429
gyrA9630p.Val777Ile0.429
gyrA9635c.2334T>C0.429
gyrA9638c.2337C>G0.429
gyrA9644c.2343T>G0.500
gyrA9650c.2349G>C0.480
gyrA9656c.2355C>G0.500
gyrA9665c.2364A>C0.565
gyrA9666p.Arg789Gly0.481
gyrA9674c.2373T>C0.548
rpoB759606c.-201T>C0.889
rpoB759629c.-178T>C0.800
rpoB759644c.-163T>A0.704
rpoB759647c.-160T>C0.704
rpoB759812c.6A>T0.634
rpoB759817p.Ser4Phe0.605
rpoB759830c.24A>G0.190
rpoB760040c.234T>C0.500
rpoB760046c.240G>C0.558
rpoB760060p.Tyr85Leu0.571
rpoB760067c.261G>C0.565
rpoB760070c.264T>G0.574
rpoB760091c.285G>C0.647
rpoB760101c.295T>C0.667
rpoB760112c.306T>C0.700
rpoB760118c.312T>G0.680
rpoB760121c.315T>C0.686
rpoB760130p.Asp108Glu0.706
rpoB760139c.333A>G0.704
rpoB760142c.336C>G0.717
rpoB760181c.375T>C0.756
rpoB760184c.378A>G0.756
rpoB760196c.390C>G0.780
rpoB760223c.417T>C0.667
rpoB760235c.429T>C0.708
rpoB760283c.477G>C0.711
rpoB760298c.492G>C0.643
rpoB760307c.501T>C0.628
rpoB760310c.504G>C0.614
rpoB760328c.522G>C0.619
rpoB760331c.525G>C0.619
rpoB760340c.534G>T0.625
rpoB760361c.555T>C0.605
rpoB760370c.564C>G0.610
rpoB760376p.Asp190Glu0.610
rpoB760380p.Thr192Leu0.579
rpoB760406c.600G>C0.605
rpoB760412c.606C>G0.615
rpoB760424c.618C>G0.605
rpoB760430c.624T>C0.625
rpoB760475c.669A>G0.641
rpoB760481c.675G>C0.632
rpoB760484c.678A>G0.632
rpoB760522p.Ser239Asn0.553
rpoB760532c.726T>C0.514
rpoB760533p.Val243Thr0.486
rpoB760541c.735G>C0.514
rpoB760547c.741G>C0.538
rpoB760563p.Arg253Met0.512
rpoB760591p.Val262Ala0.597
rpoB760611c.805T>C0.589
rpoB760646c.840C>G0.607
rpoB760655c.849A>G0.627
rpoB760661c.855A>C0.618
rpoB760670c.864G>C0.625
rpoB760674c.868T>C0.632
rpoB760679c.873A>G0.611
rpoB760683c.877T>C0.642
rpoB760715c.909C>G0.660
rpoB760718c.912C>T0.644
rpoB760724c.918T>C0.628
rpoB760730c.924T>C0.605
rpoB760751c.945G>C0.545
rpoB760757c.951T>C0.516
rpoB760759p.Val318Ala0.516
rpoB760769c.963C>G0.556
rpoB760775c.969G>C0.429
rpoB760776c.970T>A0.441
rpoB760793c.987A>G0.600
rpoB760805c.999G>C0.652
rpoB760817c.1011A>G0.500
rpoB760820c.1014T>C0.462
rpoB760826c.1020C>G0.417
rpoB760830c.1024T>C0.417
rpoB760838p.Glu344Asp0.273
rpoB760841c.1035T>C0.333
rpoB760845p.Thr347Pro0.333
rpoB760848p.Thr348Ala0.250
rpoB760869p.Val355Ile0.788
rpoB760886c.1080A>G0.788
rpoB760889c.1083C>T0.771
rpoB760925c.1119T>C0.795
rpoB760928c.1122G>C0.789
rpoB760934c.1128C>T0.769
rpoB760946c.1140A>G0.763
rpoB760949c.1143C>T0.775
rpoB760982c.1176G>C0.738
rpoB760985c.1179G>C0.738
rpoB760991c.1185G>C0.750
rpoB761006c.1200C>G0.744
rpoB761015c.1209G>C0.738
rpoB761021c.1215G>C0.750
rpoB761027c.1221A>G0.733
rpoB761036c.1230G>C0.767
rpoB761037c.1231T>C0.773
rpoB761057c.1251G>C0.692
rpoB761102c.1296A>G0.730
rpoB761129c.1323G>C0.724
rpoB761132c.1326G>T0.700
rpoB761133c.1327T>C0.700
rpoB761150c.1344A>C0.727
rpoB761153c.1347G>C0.706
rpoB761165c.1359G>C0.758
rpoB761180c.1374A>C0.788
rpoB761189c.1383T>C0.800
rpoB761195c.1389G>C0.812
rpoB761207c.1401C>T0.833
rpoB761213c.1407G>C0.833
rpoB761219c.1413G>C0.806
rpoB761249c.1443A>G0.788
rpoB761255c.1449T>G0.800
rpoB761261c.1455G>T0.800
rpoB761306c.1500C>G0.706
rpoB761312c.1506G>C0.697
rpoB761327c.1521A>G0.719
rpoB761330c.1524G>C0.719
rpoB761354c.1548C>T0.657
rpoB761360c.1554T>C0.586
rpoB761362p.Ser519Thr0.586
rpoB761373p.Val523His0.536
rpoB761408c.1602G>C0.641
rpoB761414c.1608A>G0.641
rpoB761423c.1617T>C0.615
rpoB761435c.1629T>C0.517
rpoB761438c.1632G>C0.517
rpoB761439p.Asp545Lys0.517
rpoB761444c.1638T>C0.517
rpoB761447c.1641C>G0.517
rpoB761452p.Val549Glu0.517
rpoB761457p.Pro551Ser0.517
rpoB761477c.1671C>G0.645
rpoB761492c.1686G>C0.667
rpoB761510c.1704T>C0.727
rpoB761537c.1731C>G0.800
rpoB761570c.1764T>C0.824
rpoB761573c.1767C>G0.824
rpoB761579c.1773G>C0.824
rpoB761588c.1782C>T0.833
rpoB761606c.1800C>G0.800
rpoB761612c.1806G>C0.767
rpoB761615c.1809A>C0.762
rpoB761636c.1830G>T0.744
rpoB761639c.1833G>A0.750
rpoB761645c.1839C>G0.762
rpoB761648c.1842T>C0.762
rpoB761657c.1851C>G0.773
rpoB761675c.1869G>C0.766
rpoB761720c.1914C>G0.633
rpoB761725p.Glu640Ala0.633
rpoB761732c.1926C>G0.633
rpoB761735c.1929C>G0.656
rpoB761747c.1941G>C0.657
rpoB761750c.1944G>C0.667
rpoB761765c.1959T>C0.622
rpoB761772p.His656Ala0.614
rpoB761778p.Asn658Asp0.628
rpoB761791p.Arg662His0.630
rpoB761813c.2007T>C0.660
rpoB761815p.Ala670Glu0.660
rpoB761834c.2028T>C0.711
rpoB761848p.Cys681Ser0.744
rpoB761852c.2046C>G0.744
rpoB761858c.2052G>C0.733
rpoB761873c.2067A>C0.766
rpoB761885c.2079T>C0.733
rpoB761906c.2100C>G0.628
rpoB761909c.2103T>C0.614
rpoB761912c.2106T>C0.643
rpoB761915p.Asp703Glu0.659
rpoB761916p.Asp704Asn0.650
rpoB761948c.2142G>C0.667
rpoB761954c.2148C>G0.683
rpoB762008c.2202C>T0.725
rpoB762014c.2208C>T0.711
rpoB762017c.2211A>G0.684
rpoB762053c.2247T>C0.619
rpoB762062c.2256T>C0.628
rpoB762065c.2259T>C0.650
rpoB762083c.2277T>C0.590
rpoB762086c.2280G>C0.575
rpoB762101c.2295C>G0.605
rpoB762114p.Ile770Val0.611
rpoB762131c.2325C>G0.632
rpoB762140c.2334G>C0.600
rpoB762143c.2337T>C0.600
rpoB762149c.2343G>C0.619
rpoB762167c.2361T>C0.757
rpoB762176c.2370T>C0.750
rpoB762185c.2379G>C0.730
rpoB762206c.2400C>G0.714
rpoB762233c.2427G>C0.611
rpoB762246c.2440C>T0.571
rpoB762254c.2448T>G0.556
rpoB762257c.2451C>G0.571
rpoB762266c.2460T>C0.586
rpoB762284c.2478G>C0.640
rpoB762293c.2487T>C0.640
rpoB762314c.2508C>T0.710
rpoB762317c.2511A>G0.667
rpoB762329c.2523G>C0.667
rpoB762338c.2532T>C0.677
rpoB762347c.2541T>C0.697
rpoB762362p.Glu852Asp0.676
rpoB762369c.2563T>C0.657
rpoB762398c.2592T>C0.750
rpoB762401c.2595G>C0.771
rpoB762404c.2598T>C0.771
rpoB762410c.2604T>C0.800
rpoB762416c.2610A>G0.794
rpoB762419c.2613C>G0.800
rpoB762434c.2628T>C0.795
rpoB762449c.2643C>A0.769
rpoB762467c.2661C>T0.771
rpoB762488c.2682G>C0.735
rpoB762489p.Val895Gln0.735
rpoB762509c.2703T>G0.730
rpoB762510p.Ala902Pro0.730
rpoB762521c.2715C>T0.756
rpoB762533c.2727T>C0.750
rpoB762536c.2730T>C0.750
rpoB762537c.2731T>C0.750
rpoB762551c.2745C>G0.776
rpoB762581c.2775T>C0.762
rpoB762582c.2776T>C0.750
rpoB762729p.Gln975Lys0.676
rpoB762736p.Ala977Glu0.621
rpoB762744p.Gln980Ala0.643
rpoB762750p.Leu982Met0.667
rpoB762753c.2947T>C0.679
rpoB762758c.2952G>C0.759
rpoB762782c.2976T>C0.781
rpoB762785p.Asp993Glu0.781
rpoB762788c.2982G>C0.781
rpoB762789p.Leu995Met0.781
rpoB762794c.2988C>G0.781
rpoB762799p.Ala998Gly0.788
rpoB762810p.Ala1002Ser0.658
rpoB762813p.Met1003Val0.667
rpoB762818c.3012C>G0.667
rpoB762827c.3021G>C0.689
rpoB762857c.3051C>G0.659
rpoB762860c.3054G>C0.643
rpoB762863c.3057T>C0.643
rpoB762929c.3123G>C0.686
rpoB762989c.3183G>C0.545
rpoB763013c.3207C>G0.651
rpoB763028c.3222T>C0.733
rpoB763031c.3225T>G0.750
rpoB763034c.3228C>G0.761
rpoB763040c.3234C>G0.717
rpoB763070c.3264T>C0.775
rpoB763085c.3279C>G0.757
rpoB763115c.3309T>C0.698
rpoB763136c.3330C>T0.756
rpoB763148c.3342G>C0.750
rpoB763158c.3352C>T0.738
rpoB763166c.3360A>G0.733
rpoB763190c.3384C>T0.711
rpoB763202c.3396A>G0.636
rpoB763205c.3399G>C0.622
rpoB763206c.3400A>T0.622
rpoB763214c.3408T>C0.653
rpoB763226c.3420A>G0.660
rpoB763227c.3421C>T0.667
rpoB763238c.3432T>C0.667
rpoB763253c.3447G>C0.596
rpoB763256c.3450G>A0.600
rpoB763268c.3462C>G0.622
rpoB763283c.3477T>C0.611
rpoB763284c.3478C>T0.588
rpoB763310c.3504C>T0.375
rpoB763316c.3510T>C0.375
rpoB763319c.3513T>C0.375
rpoB763322c.3516G>C0.360
rpoC763333c.-37G>C0.360
rpoC763338c.-32A>G0.360
rpoC763351c.-19T>C0.674
rpoC763352c.-18T>A0.674
rpoC763402c.33C>G0.723
rpoC763411c.42T>G0.750
rpoC763414c.45T>C0.750
rpoC763441c.72C>T0.809
rpoC763444c.75T>C0.809
rpoC763456c.87A>G0.814
rpoC763486c.117T>G0.757
rpoC763528c.159G>A0.794
rpoC763546c.177A>G0.794
rpoC763570c.201G>C0.788
rpoC763573c.204G>C0.788
rpoC763594c.225C>T0.647
rpoC763633c.264T>C0.674
rpoC763636c.267T>C0.696
rpoC763660c.291T>G0.689
rpoC763675c.306C>G0.680
rpoC763696c.327T>C0.718
rpoC763702c.333C>G0.700
rpoC763717c.348T>C0.707
rpoC763723c.354G>C0.651
rpoC763732c.363C>G0.651
rpoC763741c.372C>T0.651
rpoC763744c.375G>C0.667
rpoC763765c.396T>C0.674
rpoC763774c.405G>C0.739
rpoC763807c.438T>C0.675
rpoC763816c.447C>G0.619
rpoC763835p.Ala156Met0.639
rpoC763853p.Val162Ile0.647
rpoC763858c.489A>G0.636
rpoC763872p.Gly168Ala0.583
rpoC763876p.Glu169Asp0.583
rpoC763877c.508C>T0.583
rpoC763888c.519G>C0.636
rpoC763891c.522G>C0.652
rpoC763894c.525A>G0.652
rpoC763900c.531G>C0.679
rpoC763936c.567C>G0.618
rpoC763945c.576T>C0.629
rpoC763951c.582G>C0.649
rpoC763960c.591T>C0.491
rpoC763991p.Ile208Leu0.587
rpoC763996c.627T>C0.587
rpoC764002c.633C>G0.614
rpoC764005c.636G>C0.614
rpoC764024c.655T>C0.622
rpoC764032p.Asp221Glu0.619
rpoC764040p.Ser224Thr0.610
rpoC764044c.675T>C0.610
rpoC764059c.690G>T0.619
rpoC764083c.714A>G0.659
rpoC764098c.729A>G0.650
rpoC764101c.732C>G0.641
rpoC764102p.Val245Ile0.641
rpoC764112p.Tyr248Phe0.650
rpoC764116c.747C>T0.650
rpoC764131c.762T>C0.643
rpoC764140c.771C>T0.651
rpoC764188c.819A>G0.788
rpoC764195p.Ser276Ile0.778
rpoC764203c.834G>C0.778
rpoC764206c.837T>C0.808
rpoC764215c.846A>G0.839
rpoC764236c.867G>A0.862
rpoC764248c.879C>G0.889
rpoC764257c.888G>C0.870
rpoC764266c.897T>C0.864
rpoC764269c.900G>C0.864
rpoC764272c.903G>C0.864
rpoC764278c.909A>G0.870
rpoC764338c.969G>A0.765
rpoC764353c.984G>C0.725
rpoC764365c.996C>T0.722
rpoC764380c.1011G>C0.750
rpoC764381c.1012T>A0.750
rpoC764387c.1018T>C0.711
rpoC764405c.1036A>C0.674
rpoC764419c.1050C>G0.651
rpoC764431c.1062G>C0.667
rpoC764434c.1065A>G0.667
rpoC764446c.1077T>C0.571
rpoC764449c.1080G>C0.571
rpoC764452c.1083T>C0.571
rpoC764458c.1089G>C0.558
rpoC764461c.1092A>G0.558
rpoC764489c.1120C>T0.556
rpoC764497c.1128A>G0.540
rpoC764510c.1141C>T0.511
rpoC764521c.1152T>C0.545
rpoC764527c.1158C>T0.524
rpoC764536c.1167G>C0.523
rpoC764539c.1170C>G0.523
rpoC764554c.1185C>T0.551
rpoC764560c.1191T>C0.574
rpoC764566c.1197C>G0.600
rpoC764575c.1206T>G0.592
rpoC764581c.1212T>C0.588
rpoC764593c.1224C>T0.615
rpoC764611c.1242G>T0.596
rpoC764650c.1281G>C0.643
rpoC764651c.1282T>A0.643
rpoC764752c.1383G>C0.683
rpoC764764c.1395T>C0.702
rpoC764809c.1440C>T0.796
rpoC764815c.1446A>G0.818
rpoC764827c.1458G>C0.788
rpoC764858c.1489T>C0.792
rpoC764872c.1503A>G0.812
rpoC764888c.1519T>C0.800
rpoC764911c.1542A>G0.816
rpoC764932c.1563C>A0.822
rpoC764935c.1566T>C0.830
rpoC764948c.1579T>C0.792
rpoC764968c.1599T>C0.860
rpoC764995c.1626C>G0.804
rpoC765019c.1650A>G0.762
rpoC765034c.1665T>C0.750
rpoC765040c.1671T>C0.742
rpoC765041c.1672T>C0.742
rpoC765047c.1678T>C0.719
rpoC765053c.1684T>A0.719
rpoC765073c.1704G>C0.705
rpoC765076c.1707A>G0.705
rpoC765079c.1710T>G0.694
rpoC765082c.1713G>C0.694
rpoC765085c.1716T>G0.694
rpoC765089c.1720T>C0.694
rpoC765103c.1734G>T0.698
rpoC765208c.1839T>G0.400
rpoC765220c.1851A>G0.423
rpoC765233p.Ala622Ser0.423
rpoC765241c.1872C>T0.440
rpoC765244c.1875T>C0.440
rpoC765247c.1878C>G0.440
rpoC765248c.1879T>C0.440
rpoC765251c.1882A>T0.458
rpoC765292c.1923G>C0.677
rpoC765298c.1929G>C0.688
rpoC765300p.Val644Ala0.688
rpoC765319c.1950A>G0.762
rpoC765326p.His653Ala0.730
rpoC765329p.Ser654Gly0.730
rpoC765346c.1977C>G0.780
rpoC765349c.1980T>C0.769
rpoC765352c.1983G>C0.769
rpoC765383p.Met672Leu0.852
rpoC765404p.Leu679Val0.840
rpoC765409c.2040T>C0.808
rpoC765421c.2052C>G0.808
rpoC765478c.2109T>C0.730
rpoC765499c.2130C>G0.700
rpoC765529c.2160C>T0.744
rpoC765541c.2172C>G0.750
rpoC765553c.2184C>T0.737
rpoC765556c.2187G>C0.694
rpoC765559c.2190G>C0.694
rpoC765580c.2211G>C0.743
rpoC765613p.His748Gln0.762
rpoC765625c.2256C>G0.744
rpoC765631p.Asp754Glu0.744
rpoC765700c.2331T>C0.906
rpoC765734c.2365T>C0.879
rpoC765739c.2370G>T0.879
rpoC765751c.2382C>G0.875
rpoC765753p.Asp795Ala0.875
rpoC765772c.2403C>G0.833
rpoC765784c.2415C>G0.818
rpoC765787c.2418C>T0.818
rpoC765793c.2424C>G0.829
rpoC765796c.2427C>T0.829
rpoC765811c.2442T>C0.800
rpoC765814c.2445A>G0.795
rpoC765826c.2457T>C0.789
rpoC765835c.2466C>T0.762
rpoC765850c.2481G>C0.744
rpoC765883c.2514C>G0.756
rpoC765886c.2517C>G0.738
rpoC765892c.2523T>C0.744
rpoC765937c.2568T>C0.677
rpoC765967c.2598C>T0.625
rpoC765982c.2613C>G0.632
rpoC765994c.2625A>T0.605
rpoC766010c.2641T>A0.647
rpoC766021c.2652G>C0.625
rpoC766027c.2658G>C0.619
rpoC766030c.2661C>G0.619
rpoC766043p.Gln892Glu0.630
rpoC766054c.2685C>G0.638
rpoC766082p.Ala905Gln0.630
rpoC766096c.2727G>C0.625
rpoC766129c.2760C>G0.681
rpoC766135c.2766G>A0.688
rpoC766141c.2772C>T0.688
rpoC766142c.2773C>T0.694
rpoC766174p.Asn935Lys0.689
rpoC766178p.Ile937Val0.674
rpoC766185p.Glu939Ala0.516
rpoC766189c.2820T>C0.516
rpoC766192c.2823T>C0.500
rpoC766193p.Gln942Glu0.500
rpoC766204c.2835C>T0.500
rpoC766207c.2838T>C0.485
rpoC766216c.2847T>C0.485
rpoC766219p.Asp950Glu0.471
rpoC766222c.2853T>C0.471
rpoC766226c.2857T>C0.471
rpoC766231c.2862T>G0.471
rpoC766234c.2865T>C0.471
rpoC766237c.2868T>C0.485
rpoC766240c.2871T>C0.485
rpoC766243c.2874C>G0.485
rpoC766258c.2889T>C0.718
rpoC766273c.2904T>C0.667
rpoC766274p.Ala969Thr0.667
rpoC766280p.Ser971Gly0.686
rpoC766288c.2919C>G0.694
rpoC766303c.2934C>T0.656
rpoC766312c.2943T>G0.718
rpoC766327c.2958C>A0.725
rpoC766345c.2976T>C0.744
rpoC766348c.2979A>G0.744
rpoC766357c.2988C>T0.762
rpoC766363c.2994G>C0.756
rpoC766381c.3012C>T0.738
rpoC766384c.3015A>G0.738
rpoC766408c.3039C>G0.700
rpoC766411c.3042C>G0.700
rpoC766426c.3057C>T0.727
rpoC766447c.3078T>C0.696
rpoC766462c.3093G>C0.660
rpoC766483c.3114G>C0.611
rpoC766484p.Val1039Ile0.611
rpoC766492c.3123T>C0.667
rpoC766522c.3153C>G0.667
rpoC766528c.3159T>C0.674
rpoC766531c.3162G>C0.659
rpoC766540p.Asp1057Glu0.652
rpoC766549c.3180G>C0.660
rpoC766573c.3204T>C0.609
rpoC766582c.3213C>G0.591
rpoC766583p.Gly1072Ser0.591
rpoC766591c.3222A>G0.605
rpoC766594c.3225G>C0.622
rpoC766597c.3228C>G0.609
rpoC766607p.Ile1080Leu0.692
rpoC766625c.3256C>T0.709
rpoC766630c.3261G>C0.709
rpoC766657c.3288A>G0.704
rpoC766672c.3303T>C0.706
rpoC766673p.Gly1102Asn0.694
rpoC766726c.3357T>C0.654
rpoC766738c.3369G>C0.619
rpoC766765c.3396A>C0.627
rpoC766774c.3405T>C0.638
rpoC766801c.3432C>G0.619
rpoC766804c.3435A>G0.628
rpoC766861c.3492G>C0.675
rpoC766864c.3495G>C0.675
rpoC766876c.3507C>T0.667
rpoC766882c.3513C>T0.686
rpoC766894c.3525T>C0.676
rpoC766895c.3526T>C0.676
rpoC766900c.3531T>C0.656
rpoC766933c.3564A>G0.649
rpoC766945c.3576A>G0.694
rpoC766963c.3594T>C0.686
rpoC766972c.3603G>C0.703
rpoC766996c.3627C>T0.750
rpoC767009c.3640T>A0.722
rpoC767014c.3645G>C0.730
rpoC767033c.3664T>A0.718
rpoC767059c.3690T>G0.667
rpoC767062c.3693C>A0.667
rpoC767098c.3729T>C0.674
rpoC767111c.3742C>T0.667
rpoC767119c.3750A>G0.675
rpoC767134c.3765C>A0.683
rpoC767158c.3789T>G0.659
rpoC767180p.Ala1271Gln0.690
rpoC767191c.3822C>G0.683
rpoC767206c.3837C>G0.675
rpoC767209c.3840T>C0.658
rpoC767212c.3843G>C0.641
rpoC767221c.3852C>G0.692
rpoC767230c.3861G>C0.632
rpoC767233c.3864T>C0.611
rpoC767263c.3894T>C0.576
rpoC767264p.Ala1299Gln0.548
rpoC767275c.3906T>C0.548
rpoC767278c.3909T>C0.548
rpoC767281c.3912C>G0.548
rpoC767284c.3915C>T0.586
rpsL781348c.-212C>G0.519
rpsL781353c.-207T>C0.519
rpsL781373c.-187G>C0.538
rpsL781395c.-165T>C1.000
rpsL781571c.12C>T0.698
rpsL781595c.36T>C0.737
rpsL781605p.Ile16Val0.722
rpsL781608p.Ser17Ala0.714
rpsL781628c.69T>C0.769
rpsL781631c.72G>C0.775
rpsL781649c.90T>C0.733
rpsL781655c.96T>C0.708
rpsL781700c.141G>C0.732
rpsL781703c.144G>T0.732
rpsL781715c.156T>C0.731
rpsL781728c.169T>C0.745
rpsL781736c.177T>C0.733
rpsL781742c.183C>T0.698
rpsL781748c.189C>G0.718
rpsL781754c.195G>C0.718
rpsL781760c.201T>C0.738
rpsL781772c.213C>A0.744
rpsL781808c.249C>T0.812
rpsL781811c.252C>T0.812
rpsL781832c.273T>C0.792
rpsL781838c.279G>C0.796
rpsL781841c.282C>G0.800
rpsL781865c.306G>C0.766
rpsL781868c.309T>C0.766
rpsL781871c.312G>C0.766
rpsL781877c.318T>C0.765
rpsL781892c.333A>G0.792
rpsL781898c.339A>T0.780
rpsL781916c.357T>C0.740
rpsL781929p.Gly124Ser0.740
rplC800794c.-15A>G0.459
rplC800796c.-13A>G0.472
rplC800814c.6A>G0.564
rplC800817c.9A>T0.564
rplC800844c.36T>C0.636
rplC800865c.57A>G0.529
rplC800867p.Ser20Asn0.529
rplC800874c.66A>G0.500
rplC800875p.Val23Ile0.486
rplC800880c.72A>G0.486
rplC800889c.81C>G0.543
rplC800892c.84G>C0.528
rplC800907c.99C>G0.588
rplC800916c.108A>G0.606
rplC800934c.126C>G0.567
rplC800937c.129A>G0.567
rplC800939p.Arg44Gln0.567
rplC800946c.138T>C0.567
rplC800949c.141T>C0.567
rplC800967c.159C>G0.621
rplC800970c.162T>C0.621
rplC800982c.174C>T0.536
rplC800985c.177A>G0.552
rplC801004p.Leu66Val0.552
rplC801009c.201A>C0.500
rplC801019p.Thr71Ala0.462
rplC801027c.219C>G0.462
rplC801039c.231A>G0.440
rplC801045c.237A>G0.409
rplC801047p.Tyr80Phe0.381
rplC801049c.241C>T0.421
rplC801054c.246G>C0.421
rplC801070p.Asp88Asn0.235
rplC801073p.Ser89Pro0.235
rplC801078c.270T>C0.211
rplC801081c.273C>G0.211
rplC801085p.Thr93Ala0.211
rplC801090c.282G>A0.190
rplC801099c.291T>C0.190
rplC801102c.294G>C0.200
rplC801105c.297A>G0.190
rplC801109c.301T>C0.190
rplC801114c.306C>G0.182
rplC801117c.309G>C0.182
rplC801127p.Ala107Thr0.543
rplC801132c.324T>C0.543
rplC801147c.339T>C0.559
rplC801150c.342G>C0.559
rplC801153c.345G>C0.588
rplC801156c.348T>A0.600
rplC801168c.360C>G0.658
rplC801171c.363A>G0.658
rplC801174c.366T>C0.658
rplC801180c.372C>G0.684
rplC801195c.387G>C0.659
rplC801201c.393C>T0.644
rplC801207c.399C>T0.644
rplC801246c.438C>T0.667
rplC801249c.441T>C0.667
rplC801255c.447C>T0.667
rplC801264c.456C>T0.643
rplC801267c.459A>T0.634
rplC801270c.462T>C0.605
rplC801276c.468G>C0.634
rplC801279c.471G>C0.634
rplC801282c.474G>C0.634
rplC801285c.477G>C0.634
rplC801300c.492C>G0.658
rplC801309c.501C>G0.658
rplC801312c.504G>C0.649
rplC801321c.513C>T0.618
rplC801324c.516T>C0.625
rplC801339c.531T>C0.676
rplC801341p.Leu178Gln0.676
rplC801348c.540T>G0.676
rplC801357c.549T>C0.694
rplC801367p.Ala187Thr0.714
rplC801402c.594T>C0.714
rplC801405c.597T>C0.706
rplC801423c.615G>C0.606
rplC801426c.618C>G0.606
rplC801427p.Met207Val0.606
rplC801438c.630T>C0.679
rplC801442p.Ile212Val0.654
rrs1471923r.78t>c0.594
rrs1471925r.80t>c0.633
rrs1471932r.87a>g0.613
rrs1471934r.89a>g0.588
rrs1471969r.124t>c0.633
rrs1471970r.125g>a0.633
rrs1472028r.183a>t0.350
rrs1472029r.184c>t0.350
rrs1472030r.185g>t0.350
rrs1472031r.186g>a0.350
rrs1472033r.188a>g0.350
rrs1472034r.189t>c0.350
rrs1472044r.199g>t0.500
rrs1472045r.200t>a0.500
rrs1472061r.216a>t0.500
rrs1472075r.230a>g0.630
rrs1472108r.263c>t0.643
rrs1472969r.1124a>g0.375
rrs1472970r.1125c>g0.360
rrs1472977r.1132g>c0.333
rrs1472978r.1133t>c0.333
rrs1473105r.1260g>a0.474
rrs1473120r.1275c>ct0.500
rrs1473123r.1278a>t0.500
rrs1473145r.1300c>t0.571
rrs1473166r.1321g>a0.531
rrs1473290r.1445c>t0.576
rrl1473569c.-89A>T0.333
rrl1473571c.-87C>T0.333
rrl1473651c.-7GT>G0.618
rrl1473658r.1t>a0.600
rrl1473659r.2t>a0.600
rrl1473668r.11c>t0.647
rrl1473756r.99g>a0.765
rrl1473758r.101g>t0.765
rrl1473806r.149c>t0.714
rrl1473877r.220g>a0.733
rrl1473898r.241c>t0.692
rrl1473943r.286g>t0.706
rrl1473945r.288t>a0.688
rrl1473946r.289a>t0.688
rrl1473986r.329t>c0.706
rrl1473987r.330g>a0.737
rrl1473995r.338g>t0.750
rrl1474001r.344c>t0.727
rrl1474009r.352a>g0.727
rrl1474012r.355c>t0.667
rrl1474093r.436g>t0.677
rrl1474099r.442g>a0.636
rrl1474103r.446a>t0.636
rrl1474140r.483c>t0.611
rrl1474151r.494c>t0.641
rrl1474181r.524c>t0.727
rrl1474249r.592g>t0.571
rrl1474291r.634tttcctctccggagga>t0.652
rrl1474292r.635t>g0.200
rrl1474308r.651g>t0.632
rrl1474310r.653t>g0.682
rrl1474356r.699t>c0.609
rrl1474362r.705a>g0.609
rrl1474376r.719t>c0.714
rrl1474427r.770a>c0.400
rrl1474429r.772g>c0.400
rrl1474432r.775c>g0.400
rrl1474639r.982g>a0.346
rrl1474794r.1137c>t0.429
rrl1474812r.1155g>a0.448
rrl1474823r.1166c>t0.483
rrl1474831r.1174a>g0.407
rrl1474904r.1247g>a0.481
rrl1474956r.1299c>t0.481
rrl1474960r.1303c>g0.464
rrl1474963r.1306g>t0.423
rrl1474964r.1307t>a0.423
rrl1474965r.1308g>c0.423
rrl1474970r.1313g>a0.423
rrl1475006r.1349a>t0.308
rrl1475061r.1404c>t0.227
rrl1475088r.1431a>t0.217
rrl1475199r.1542g>a0.727
rrl1475206r.1549c>t0.682
rrl1475209r.1552g>c0.682
rrl1475213r.1556c>t0.682
rrl1475249r.1592t>c0.704
rrl1475252r.1595c>t0.741
rrl1475266r.1609t>c0.704
rrl1475267r.1610g>a0.704
rrl1475275r.1618c>t0.704
rrl1475276r.1619t>c0.704
rrl1475291r.1634a>c0.720
rrl1475315r.1658a>t0.708
rrl1475355r.1698c>t0.654
rrl1475369r.1712g>t0.731
rrl1475402r.1745c>t0.667
rrl1475419r.1762c>t0.600
rrl1475429r.1772g>a0.600
rrl1475436r.1779c>t0.625
rrl1475483r.1826c>t0.667
rrl1475505r.1848g>a0.565
rrl1475526r.1869c>a0.591
rrl1475599r.1942a>g0.684
rrl1475608r.1951t>c0.700
rrl1475642r.1985t>c0.722
rrl1475657r.2000a>g0.688
rrl1475659r.2002g>t0.688
rrl1475758r.2101ac>a0.857
rrl1475763r.2106c>t0.733
rrl1475765r.2108ag>a0.733
rrl1475881r.2224t>c0.750
rrl1475988r.2331a>g0.682
rrl1476031r.2374c>t0.733
rrl1476032r.2375c>a0.786
rrl1476033r.2376t>c0.786
rrl1476034r.2377c>a0.786
rrl1476045r.2388g>t0.733
rrl1476047r.2390g>t0.733
rrl1476048r.2391g>a0.733
rrl1476049r.2392c>t0.733
rrl1476086r.2429g>a0.636
rrl1476089r.2432t>c0.636
rrl1476095r.2438c>g0.636
rrl1476106r.2449a>t0.529
rrl1476108r.2451t>c0.529
rrl1476115r.2458t>c0.529
rrl1476117r.2460g>c0.529
rrl1476214r.2557g>a0.640
rrl1476224r.2567a>g0.643
rrl1476281r.2624t>c0.552
rrl1476583r.2926g>a0.694
rrl1476584r.2927c>t0.686
rrl1476594r.2937c>t0.706
rrl1476597r.2940g>a0.667
rrl1476603r.2946g>a0.657
rrl1476608r.2951c>g0.667
rrl1476628r.2971t>a0.677
rrl1476689r.3032a>t0.583
rrl1476690r.3033c>t0.583
rrl1476693r.3036g>a0.583
rrl1476695r.3038t>a0.583
rrl1476716r.3059a>c0.654
rrl1476726r.3069a>g0.621
rrl1476732r.3075t>c0.607
rrl1476750r.3093t>c0.571
rrl1476755r.3098g>a0.556
rrl1476759r.3102t>c0.560
rrl1476770r.3113t>c0.583
rrl1476771r.3114g>a0.583
fabG11673482p.Ser15Ala0.694
fabG11673487c.48T>C0.722
fabG11673490c.51A>G0.722
fabG11673523c.84G>T0.795
fabG11673535c.96A>G0.795
fabG11673547c.108T>C0.833
fabG11673568c.129C>G0.829
fabG11673574c.135C>G0.838
fabG11673580c.141T>G0.829
fabG11673589c.150A>G0.784
fabG11673595c.156A>C0.771
fabG11673596p.Lys53Glu0.771
fabG11673602c.163C>T0.788
fabG11673607c.168T>C0.771
fabG11673615p.Glu59Val0.743
fabG11673619c.180T>C0.750
fabG11673633p.Ser65Asn0.775
fabG11673637p.Asp66Glu0.795
fabG11673641p.Val68Ile0.810
fabG11673646c.207T>C0.800
fabG11673657p.Thr73Lys0.800
fabG11673660p.Ala74Glu0.769
fabG11673664c.225A>C0.769
fabG11673667c.228A>G0.811
fabG11673679c.240T>C0.811
fabG11673685c.246C>T0.833
fabG11673710p.Leu91Ile0.848
fabG11673716p.Ala93Lys0.839
fabG11673733p.Met98Ile0.833
fabG11673748c.309A>G0.760
fabG11673749p.Lys104Arg0.739
fabG11673758p.Lys107Glu0.750
fabG11673784c.345G>C0.708
fabG11673797p.Ala120Thr0.300
fabG11673802c.363A>G0.273
fabG11673805c.366G>C0.273
fabG11673808c.369A>C0.273
fabG11673809p.Ser124Ala0.273
fabG11673829p.Asn130Lys0.214
fabG11673838c.399T>C0.214
fabG11673841c.402A>C0.214
fabG11673844p.Met135Ile0.214
fabG11673847c.408A>C0.200
fabG11673849p.Phe137Tyr0.200
fabG11673853c.414A>C0.200
fabG11673856c.417T>C0.214
fabG11673890p.Ala151Ser0.600
fabG11673901c.462A>G0.567
fabG11673905p.Ser156Ala0.600
fabG11673916c.477A>C0.643
fabG11673917p.Val160Leu0.643
fabG11673922c.483T>C0.643
fabG11673941p.Ala168Ser0.600
fabG11673955c.516G>C0.636
fabG11673961c.522A>C0.606
fabG11673985c.546C>A0.600
fabG11674006p.Asp189Glu0.625
fabG11674018c.579G>C0.458
fabG11674021c.582G>C0.435
fabG11674024c.585T>C0.455
fabG11674033c.594T>C0.476
fabG11674037p.Gln200Ala0.476
fabG11674042c.603G>C0.476
fabG11674049p.Gln204Asp0.476
fabG11674054c.615T>C0.476
fabG11674060c.621A>G0.476
fabG11674063c.624G>C0.476
fabG11674079p.Pro214Ala0.645
fabG11674114c.675T>A0.732
fabG11674123c.684T>C0.714
fabG11674126c.687G>C0.714
fabG11674132c.693T>C0.682
fabG11674136p.Ser233Ala0.682
fabG11674141c.702T>C0.698
fabG11674171c.732T>C0.730
inhA1674255c.54C>T0.708
inhA1674279c.78A>C0.538
inhA1674280p.Arg27Lys0.538
inhA1674284p.Val28Ala0.500
inhA1674296p.Gln32Pro0.500
inhA1674303c.102C>G0.438
inhA1674307c.106C>T0.471
inhA1674315c.114C>G0.526
inhA1674321c.120G>T0.588
inhA1674324c.123C>T0.588
inhA1674331c.130C>T0.611
inhA1674336c.135G>C0.611
inhA1674352p.Thr51Ala0.387
inhA1674368p.Ala56Glu0.611
inhA1674375c.174C>G0.647
inhA1674382p.Leu61Ile0.647
inhA1674387c.186A>G0.647
inhA1674399c.198A>G0.647
inhA1674419p.Ser73Asn0.400
inhA1674428p.Gly76Glu0.500
inhA1674438c.237C>G0.500
inhA1674440p.Glu80Ala0.500
inhA1674443p.Ala81Glu0.500
inhA1674450c.249G>C0.500
inhA1674452p.Ala84Asp0.500
inhA1674471c.270G>C0.615
inhA1674480c.279T>C0.632
inhA1674486c.285T>C0.632
inhA1674504c.303C>G0.550
inhA1674507c.306G>C0.550
inhA1674537c.336C>G0.611
inhA1674542p.Ala114Glu0.588
inhA1674546c.345T>C0.588
inhA1674549c.348G>C0.611
inhA1674555c.354G>A0.647
inhA1674561c.360C>T0.765
inhA1674582c.381T>C0.812
inhA1674585c.384T>C0.812
inhA1674589p.Met130Leu0.812
inhA1674601p.Leu134Thr0.800
inhA1674624c.423A>C0.786
inhA1674660c.459G>C0.812
inhA1674672c.471C>G0.818
inhA1674703c.502T>C0.696
inhA1674708c.507G>A0.727
inhA1674718c.517A>C0.789
inhA1674723c.522C>T0.636
inhA1674738c.537C>G0.579
inhA1674741c.540C>T0.556
inhA1674746p.Tyr182Phe0.692
inhA1674750c.549T>C0.692
inhA1674753c.552G>C0.692
inhA1674756c.555T>C0.692
inhA1674759c.558G>C0.692
inhA1674774c.573A>G0.765
inhA1674780c.579T>G0.778
inhA1674789c.588G>C0.760
inhA1674801c.600T>C0.760
inhA1674822c.621C>G0.762
inhA1674828c.627G>A0.762
inhA1674846p.Ile215Met0.739
inhA1674855c.654C>G0.739
inhA1674864c.663C>T0.720
inhA1674870c.669T>C0.808
inhA1674879c.678T>C0.792
inhA1674903c.702T>C0.750
inhA1674904p.Ala235Pro0.750
inhA1674909c.708G>A0.750
inhA1674942c.741T>G0.792
inhA1674960c.759C>G0.864
inhA1674987c.786C>T0.727
inhA1674993c.792G>C0.600
inhA1674994p.His265Ser0.600
inhA1674999c.798C>G0.529
inhA1675008c.807C>T0.474
rpsA1833512c.-30AC>A0.444
rpsA1833518c.-24C>A0.444
rpsA1833532c.-10A>C0.486
rpsA1833554p.Thr5Ala0.524
rpsA1833568c.27G>C0.619
rpsA1833589c.48A>T0.659
rpsA1833595c.54T>C0.667
rpsA1833661c.120A>G0.696
rpsA1833667c.126C>G0.696
rpsA1833721c.180A>G0.660
rpsA1833724c.183C>G0.652
rpsA1833727c.186G>C0.652
rpsA1833742c.201A>G0.633
rpsA1833745c.204G>C0.625
rpsA1833748c.207C>G0.625
rpsA1833787c.246C>G0.605
rpsA1833790c.249T>C0.617
rpsA1833802c.261A>G0.622
rpsA1833811c.270G>T0.638
rpsA1833838c.297G>C0.614
rpsA1833841c.300C>G0.614
rpsA1833847c.306C>G0.605
rpsA1833856c.315A>G0.585
rpsA1833874c.333T>C0.575
rpsA1833928c.387G>C0.650
rpsA1833940c.399C>G0.682
rpsA1833971c.430C>T0.667
rpsA1833979c.438T>C0.661
rpsA1834000c.459G>C0.644
rpsA1834021c.480C>T0.651
rpsA1834030c.489C>G0.667
rpsA1834099c.558C>G0.682
rpsA1834102c.561T>C0.652
rpsA1834105c.564C>G0.652
rpsA1834108c.567C>G0.652
rpsA1834123c.582C>G0.680
rpsA1834150c.609G>C0.500
rpsA1834153c.612T>C0.500
rpsA1834154p.Asn205Gln0.500
rpsA1834157c.616T>C0.500
rpsA1834162c.621A>G0.526
rpsA1834165c.624A>G0.526
rpsA1834169p.Thr210Ala0.571
rpsA1834177c.636A>C0.643
rpsA1834189c.648G>C0.674
rpsA1834195c.654G>C0.682
rpsA1834210c.669C>T0.689
rpsA1834222c.681T>C0.674
rpsA1834231c.690T>C0.700
rpsA1834234c.693G>C0.737
rpsA1834249c.708T>C0.667
rpsA1834261c.720A>G0.588
rpsA1834262c.721T>A0.588
rpsA1834303c.762T>C0.705
rpsA1834306c.765T>C0.705
rpsA1834348c.807T>C0.769
rpsA1834366c.825A>G0.755
rpsA1834396c.855G>C0.760
rpsA1834411c.870T>C0.692
rpsA1834417c.876G>C0.692
rpsA1834423c.882G>C0.698
rpsA1834435c.894G>C0.694
rpsA1834451c.910T>C0.689
rpsA1834465c.924T>C0.675
rpsA1834468c.927A>G0.650
rpsA1834489c.948T>C0.676
rpsA1834528c.987T>C0.735
rpsA1834540c.999G>C0.774
rpsA1834546c.1005T>C0.706
rpsA1834609c.1068T>C0.600
rpsA1834633c.1092A>G0.469
rpsA1834639c.1098T>C0.469
rpsA1834654p.Glu371Asp0.487
rpsA1834684c.1143C>T0.543
rpsA1834690c.1149T>C0.500
rpsA1834732c.1191T>C0.484
rpsA1834733p.Ala398Ser0.484
rpsA1834738c.1197A>G0.484
rpsA1834753c.1212T>C0.500
rpsA1834765p.Glu408Asp0.500
rpsA1834775p.Ala412Thr0.548
rpsA1834780c.1239A>G0.562
rpsA1834786c.1245A>G0.548
rpsA1834789c.1248T>C0.548
rpsA1834792c.1251G>C0.548
rpsA1834849c.1308C>G0.545
rpsA1834852c.1311C>G0.545
rpsA1834924c.1383T>C0.278
rpsA1834930c.1389A>G0.278
rpsA1834942c.1401C>T0.312
rpsA1834948c.1407G>A0.333
rpsA1834949c.1408C>T0.333
rpsA1834954c.1413G>C0.333
rpsA1834957c.1416C>G0.312
rpsA1834966c.1425A>G0.333
tlyA1917940p.Val1Met0.778
tlyA1917943p.Ala2Ser0.778
tlyA1917951c.12T>C0.773
tlyA1917972c.33A>G1.000
tlyA1917975c.36C>G0.792
tlyA1917981c.42G>C0.800
tlyA1917990c.51G>C0.810
tlyA1917993c.54A>G0.800
tlyA1917996c.57A>G0.857
tlyA1918002c.63A>G0.870
tlyA1918036p.Arg33Ser0.840
tlyA1918048p.Leu37Met0.778
tlyA1918053c.114G>C0.778
tlyA1918056c.117G>C0.778
tlyA1918057p.Val40Arg0.778
tlyA1918065c.126G>C0.778
tlyA1918067p.Ala43Gly0.737
tlyA1918077c.138G>C0.737
tlyA1918078p.Ser47Ala0.737
tlyA1918082p.Asp48Val0.737
tlyA1918087p.Thr50Ala0.737
tlyA1918092c.153G>C0.737
tlyA1918103p.Val55Ala0.783
tlyA1918111p.Ser58Gly0.783
tlyA1918121p.Ala61Gly0.692
tlyA1918128c.189A>C0.692
tlyA1918137c.198A>C0.680
tlyA1918149c.210A>C0.533
tlyA1918150p.Val71Ile0.533
tlyA1918155c.216T>C0.533
tlyA1918164p.Glu75Asp0.533
tlyA1918167c.228G>C0.471
tlyA1918172p.Ala78Gly0.471
tlyA1918177p.Ala80Ser0.438
tlyA1918182c.243G>C0.438
tlyA1918184p.Ala82Val0.500
tlyA1918191c.252G>C0.550
tlyA1918197c.258T>C0.522
tlyA1918206c.267G>C0.474
tlyA1918212c.273A>G0.450
tlyA1918218c.279C>G0.450
tlyA1918221c.282T>C0.450
tlyA1918224c.285G>C0.450
tlyA1918236c.297A>C0.429
tlyA1918242c.303G>C0.350
tlyA1918245c.306C>T0.389
tlyA1918248c.309T>C0.438
tlyA1918251c.312T>G0.412
tlyA1918258p.His107Glu0.412
tlyA1918271p.Ala111Val0.438
tlyA1918275c.336T>C0.438
tlyA1918278c.339C>G0.500
tlyA1918308c.369C>T0.655
tlyA1918310p.Asn124Ser0.655
tlyA1918315p.Pro126Ser0.655
tlyA1918323c.384G>C0.655
tlyA1918326c.387G>C0.655
tlyA1918330p.Leu131Val0.633
tlyA1918346p.Ala136Val0.500
tlyA1918352p.Gly138Asp0.579
tlyA1918356c.417C>G0.524
tlyA1918359c.420A>G0.524
tlyA1918362c.423G>C0.524
tlyA1918366p.Ala143Ser0.550
tlyA1918377c.438T>G0.579
tlyA1918379p.Arg147Pro0.579
tlyA1918382p.Val148Ala0.579
tlyA1918389c.450G>C0.550
tlyA1918392c.453A>C0.550
tlyA1918417c.478T>C0.591
tlyA1918422c.483T>C0.591
tlyA1918442p.Val168Ala0.357
tlyA1918446c.507A>C0.357
tlyA1918457p.Arg173His0.286
tlyA1918459p.Asp174Asn0.308
tlyA1918464c.525C>G0.308
tlyA1918476c.537A>C0.267
tlyA1918477p.Leu180Met0.267
tlyA1918488c.549G>A0.312
tlyA1918506c.567A>G0.357
tlyA1918509c.570T>C0.308
tlyA1918596c.657C>T0.545
tlyA1918604p.Ser222Thr0.545
tlyA1918616p.Lys226Thr0.545
tlyA1918620c.681C>G0.524
tlyA1918635c.696C>G0.545
tlyA1918638c.699A>G0.600
tlyA1918647c.708T>C0.632
katG2154126c.1986G>A0.481
katG2154135c.1977C>G0.481
katG2154858c.1254T>G0.182
katG2154879c.1233G>C0.267
katG2154892p.Glu407Ala0.250
katG2154902c.1210A>G0.200
katG2154903c.1209T>C0.200
katG2154915p.Glu399Asp0.200
katG2154920c.1192G>A0.200
katG2154927c.1185A>C0.200
katG2155017c.1095C>G0.150
katG2155023c.1089G>C0.263
katG2155029c.1083G>C0.300
katG2155035c.1077G>C0.391
katG2155047c.1065G>C0.400
katG2155054p.Tyr353Phe0.423
katG2155056c.1056T>C0.423
katG2155062c.1050A>C0.407
katG2155065c.1047G>C0.407
katG2155068c.1044A>G0.407
katG2155080c.1032C>G0.429
katG2155092c.1020C>T0.481
katG2155113c.999G>C0.500
katG2155119c.993A>G0.520
katG2155131c.981T>C0.500
katG2155145p.Asn323Pro0.520
katG2155152c.960T>G0.500
katG2155155c.957G>C0.500
katG2155179c.933G>A0.462
katG2155185c.927A>G0.462
katG2155190p.Thr308Ser0.500
katG2155191c.921T>A0.500
katG2155194c.918G>A0.500
katG2155200c.912A>G0.556
katG2155350c.762G>C0.400
katG2155355p.Arg253Gly0.400
katG2155356c.756A>G0.400
katG2155368c.744A>G0.455
katG2155376p.Val246Ile0.455
katG2155626c.486C>G0.682
katG2155632c.480T>G0.696
katG2155637p.Leu159Ile0.696
katG2155641p.Lys157Asn0.727
katG2155661p.Val151Ile0.833
katG2155680c.432C>G0.840
katG2155691c.421A>G0.774
katG2155695c.417G>C0.800
katG2155704c.408G>C0.800
katG2155716c.396A>C0.806
katG2155722c.390C>G0.812
katG2155728c.384C>G0.750
katG2155742p.Gly124Gln0.750
katG2155743c.369C>G0.750
katG2155782c.330G>C0.800
katG2155785c.327A>G0.800
katG2155796p.Ala106Ser0.741
katG2155806c.306A>G0.741
kasA2518121p.Gln3Lys0.375
kasA2518132c.18C>T0.353
kasA2518138c.24T>C0.389
kasA2518146p.Phe11Tyr0.286
kasA2518162c.48G>A0.611
kasA2518174c.60A>G0.579
kasA2518190p.Ser26Ala0.522
kasA2518199p.Ile29Val0.560
kasA2518220c.106C>T0.636
kasA2518234c.120G>A0.625
kasA2518248p.Ala45Val0.652
kasA2518261p.Glu49Asp0.652
kasA2518263p.Phe50Tyr0.652
kasA2518265p.Val51Ile0.652
kasA2518351c.237C>T0.500
kasA2518366c.252G>A0.500
kasA2518370p.Met86Leu0.500
kasA2518374p.Gly87Ala0.500
kasA2518379c.265T>C0.538
kasA2518384c.270G>C0.538
kasA2518385p.Gly91Ser0.538
kasA2518388p.Gly92Thr0.538
kasA2518396c.282A>G0.600
kasA2518403c.289T>A0.643
kasA2518413p.Ser100Asn0.783
kasA2518421p.Val103Leu0.800
kasA2518429c.315A>C0.808
kasA2518439p.Ala109Ser0.840
kasA2518444c.330T>C0.840
kasA2518447c.333T>G0.840
kasA2518459c.345T>C0.743
kasA2518462c.348A>C0.743
kasA2518468c.354A>C0.722
kasA2518474c.360G>A0.703
kasA2518480c.366T>C0.722
kasA2518483c.369C>G0.684
kasA2518504c.390T>C0.700
kasA2518506p.Ala131Glu0.700
kasA2518519c.405G>C0.683
kasA2518528c.414C>G0.618
kasA2518540c.426T>C0.633
kasA2518561c.447T>C0.571
kasA2518567c.453G>C0.500
kasA2518570c.456G>C0.500
kasA2518573c.459G>C0.500
kasA2518574p.Ile154Val0.500
kasA2518579c.465T>C0.481
kasA2518588c.474T>C0.571
kasA2518591c.477G>C0.571
kasA2518609p.Met165Ile0.630
kasA2518624c.510C>G0.583
kasA2518639c.525G>C0.640
kasA2518657c.543G>C0.615
kasA2518672c.558G>C0.545
kasA2518678c.564C>T0.524
kasA2518684c.570C>G0.500
kasA2518693c.579C>G0.474
kasA2518696c.582C>G0.474
kasA2518702c.588C>T0.474
kasA2518705c.591T>C0.500
kasA2518711c.597A>G0.556
kasA2518714c.600A>C0.550
kasA2518732c.618C>G0.571
kasA2518744c.630C>T0.619
kasA2518747c.633C>G0.636
kasA2518768c.654C>T0.625
kasA2518777c.663C>T0.538
kasA2518783c.669T>C0.542
kasA2518789c.675G>C0.500
kasA2518792c.678C>A0.500
kasA2518795c.681C>G0.500
kasA2518825c.711T>C0.500
kasA2518864c.750G>C0.522
kasA2518879c.765A>G0.522
kasA2518885c.771T>C0.524
kasA2518898c.784T>C0.444
kasA2518906c.792A>G0.500
kasA2518910p.Leu266Met0.500
kasA2518921c.807T>C0.500
kasA2518936c.822C>G0.500
kasA2518939c.825T>C0.500
kasA2518942c.828T>C0.500
kasA2518951c.837G>C0.500
kasA2518954c.840C>G0.467
kasA2518963c.849T>C0.529
kasA2518969c.855T>G0.550
kasA2518975c.861C>G0.579
kasA2518979c.865A>C0.579
kasA2518990c.876T>G0.526
kasA2518993c.879C>G0.526
kasA2518999c.885G>C0.526
kasA2519008c.894C>G0.588
kasA2519017c.903G>C0.533
kasA2519020c.906G>C0.533
kasA2519021p.Ala303Lys0.533
kasA2519027p.Ile305Val0.571
kasA2519050c.936C>G0.727
kasA2519053c.939G>C0.714
kasA2519056c.942G>C0.714
kasA2519062c.948T>G0.750
kasA2519068c.954C>T0.750
kasA2519072p.Ala320Thr0.750
kasA2519095c.981C>A0.800
kasA2519107c.993T>C0.765
kasA2519108p.Asp332Gln0.765
kasA2519116c.1002C>G0.765
kasA2519122c.1008G>C0.765
kasA2519137c.1023T>G0.789
kasA2519158c.1044C>T0.824
kasA2519167c.1053T>G0.867
kasA2519173c.1059C>G0.824
kasA2519196p.Thr361Ser0.667
kasA2519215c.1101C>T0.636
kasA2519260c.1146T>G0.545
kasA2519263c.1149C>T0.545
kasA2519266c.1152C>T0.545
kasA2519269c.1155C>T0.545
kasA2519272c.1158C>G0.545
kasA2519281c.1167G>T0.545
kasA2519287c.1173T>C0.545
kasA2519295p.Tyr394Phe0.600
kasA2519299c.1185C>T0.600
kasA2519338c.1224T>C0.500
ahpC2726198c.6A>T0.167
ahpC2726204c.12A>G0.167
ahpC2726210c.18T>C0.174
ahpC2726216c.24T>C0.174
ahpC2726219c.27A>G0.174
ahpC2726232p.Gln14Glu0.174
ahpC2726243c.51T>G0.174
ahpC2726244c.52C>T0.167
ahpC2726251p.Gly20Ala0.154
ahpC2726255c.63T>C0.250
ahpC2726258c.66C>T0.211
ahpC2726303c.111T>C0.520
ahpC2726311p.Ser40Asn0.478
ahpC2726315p.Asp41Glu0.478
ahpC2726318p.Glu42Asp0.458
ahpC2726322p.Pro44Ala0.458
ahpC2726330c.138G>A0.556
ahpC2726336c.144G>C0.556
ahpC2726348c.156T>C0.625
ahpC2726357c.165A>G0.619
ahpC2726366c.174G>C0.609
ahpC2726378c.186T>G0.519
ahpC2726387c.195C>T0.500
ahpC2726390c.198G>C0.500
ahpC2726393c.201G>C0.500
ahpC2726397p.Ser69Gly0.500
ahpC2726408c.216T>C0.500
ahpC2726414c.222G>A0.483
ahpC2726419p.Glu76Ala0.464
ahpC2726432c.240C>G0.188
ahpC2726436p.Ile82Val0.214
ahpC2726444c.252G>T0.200
ahpC2726447c.255T>G0.200
ahpC2726453c.261T>C0.200
ahpC2726462c.270A>G0.200
ahpC2726467p.Ala92Val0.200
ahpC2726471c.279T>C0.200
ahpC2726475p.Gln95Asn0.200
ahpC2726483c.291T>C0.188
ahpC2726486c.294A>T0.188
ahpC2726493p.Asn101Glu0.312
ahpC2726506p.Thr105Lys0.333
ahpC2726508c.316T>C0.333
ahpC2726528c.336C>G0.368
ahpC2726540c.348C>G0.353
ahpC2726543c.351A>G0.353
ahpC2726546c.354C>G0.353
ahpC2726551p.Gln120Leu0.353
ahpC2726556p.Ala122Thr0.375
ahpC2726561c.369T>C0.375
ahpC2726564c.372C>G0.353
ahpC2726579c.387T>C0.565
ahpC2726591c.399C>G0.542
ahpC2726593p.Val134Ala0.520
ahpC2726600c.408T>C0.520
ahpC2726601p.Ile137Leu0.520
ahpC2726638p.Ala149Val0.700
ahpC2726645c.453C>G0.688
ahpC2726657c.465A>C0.686
ahpC2726669p.Asp159Glu0.657
ahpC2726672c.480G>A0.657
ahpC2726675c.483A>G0.676
ahpC2726681c.489A>C0.686
ahpC2726687c.495C>G0.686
ahpC2726693c.501C>G0.686
ahpC2726696c.504C>G0.686
ahpC2726717c.525A>G0.722
ahpC2726747c.555A>C0.657
folC2746150c.1449A>C0.667
folC2746158c.1441A>G0.591
folC2746162c.1437C>G0.591
folC2746166p.Ala478Val0.619
folC2746171c.1428C>G0.619
folC2746174c.1425T>G0.619
folC2746183c.1416A>G0.619
folC2746282c.1317A>G0.250
folC2746285c.1314A>G0.231
folC2746308p.Arg431Ser0.429
folC2746321c.1278T>C0.467
folC2746329p.Arg424Thr0.538
folC2746335p.Gly422Arg0.500
folC2746336c.1263G>C0.500
folC2746345c.1254C>G0.533
folC2746353p.Ala416Ser0.533
folC2746354c.1245C>T0.533
folC2746365p.Leu412Val0.562
folC2746375c.1224C>G0.588
folC2746390c.1209C>G0.579
folC2746393c.1206G>C0.611
folC2746401p.Ser400Ala0.550
folC2746402c.1197A>G0.609
folC2746416p.Glu395Gln0.654
folC2746420c.1179T>G0.680
folC2746426c.1173C>G0.680
folC2746438c.1161C>G0.682
folC2746451p.Gly383Ala0.708
folC2746471c.1128G>T0.708
folC2746478p.Phe374Tyr0.696
folC2746480c.1119T>G0.667
folC2746531c.1068C>G0.364
folC2746534c.1065A>G0.400
folC2746558c.1041C>A0.600
folC2746564c.1035T>C0.600
folC2746576c.1023G>C0.600
folC2746584c.1015A>G0.500
folC2746651c.948A>G0.615
folC2746657c.942A>G0.615
folC2746663c.936A>G0.615
folC2746677p.Ser308Ala0.500
folC2746678c.921A>G0.500
folC2746681c.918G>C0.500
folC2746684c.915G>C0.500
folC2746687c.912G>C0.500
folC2746691p.Val303Ala0.500
folC2746696c.903G>A0.500
folC2746714c.885A>T0.600
folC2747021p.Val193Ala0.211
folC2747023c.576G>C0.222
folC2747026c.573G>C0.222
folC2747032c.567T>G0.300
folC2747059c.540A>G0.190
folC2747062c.537T>C0.190
folC2747065c.534G>A0.190
folC2747071c.528G>C0.217
folC2747086c.513T>G0.263
folC2747089c.510C>G0.250
folC2747101c.498C>G0.176
folC2747107c.492C>G0.176
folC2747110c.489A>G0.167
folC2747113c.486G>C0.167
folC2747116c.483C>G0.167
folC2747134c.465G>C0.167
folC2747224c.375C>G0.188
folC2747239c.360A>G0.200
folC2747248c.351C>G0.214
folC2747264p.Gly112Ala0.200
folC2747275c.324A>G0.214
folC2747293c.306C>T0.267
folC2747302c.297T>C0.267
folC2747314c.285T>G0.286
folC2747317c.282G>C0.286
folC2747343p.Val86Ile0.357
folC2747355p.Val82Ile0.357
folC2747359c.240G>C0.385
folC2747362c.237C>G0.385
folC2747394p.Ile69Val0.571
folC2747395c.204A>G0.571
folC2747407c.192A>G0.455
folC2747442c.157A>G0.714
folC2747467p.Asp44Glu0.688
ribD2986959p.Leu41Val0.259
ribD2986978p.Ser47Thr0.269
ribD2986983p.Leu49Val0.269
ribD2986997c.159T>C0.231
ribD2987001p.Val55Ser0.231
ribD2987005p.Asp56Gly0.231
ribD2987011p.Thr58Ser0.231
ribD2987026p.Ala63Gly0.240
ribD2987033c.195C>G0.231
ribD2987042c.204A>G0.231
ribD2987046p.Val70Ile0.240
ribD2987058c.220T>C0.273
ribD2987066c.228A>G0.286
ribD2987069c.231T>C0.286
ribD2987092p.Val85Ala0.300
ribD2987105c.267C>G0.286
ribD2987108c.270T>C0.286
ribD2987474c.636T>C0.200
ribD2987486c.648C>G0.250
ribD2987493p.Val219Ile0.250
ribD2987501c.663C>G0.250
ribD2987506p.Leu223Gln0.250
ribD2987513c.675C>A0.167
ribD2987580p.Ser248Ala0.167
thyX3067223c.723C>G0.643
thyX3067232c.714G>C0.655
thyX3067246p.Thr234Ala0.609
thyX3067249p.Thr233Ser0.571
thyX3067252p.Val232Ile0.600
thyX3067274c.672G>C0.692
thyX3067277c.669G>C0.692
thyX3067281p.Val222Ala0.720
thyX3067284p.Ala221Gly0.720
thyX3067286c.660G>C0.750
thyX3067289c.657G>C0.750
thyX3067292c.654C>T0.760
thyX3067295c.651G>A0.760
thyX3067316c.630T>C0.829
thyX3067325c.621T>C0.848
thyX3067328c.618C>T0.848
thyX3067349c.597C>G0.839
thyX3067355c.591T>G0.848
thyX3067367c.579C>G0.844
thyX3067373c.573G>C0.806
thyX3067391c.555C>G0.750
thyX3067394c.552C>G0.750
thyX3067439c.507T>C0.781
thyX3067445c.501G>C0.794
thyX3067457c.489G>C0.771
thyX3067465p.Ile161Val0.812
thyX3067466c.480C>G0.812
thyX3067474p.Pro158Ala0.132
thyX3067475c.471T>C0.865
thyX3067490c.456G>C0.833
thyX3067493c.453T>C0.824
thyX3067515p.Ser144Thr0.850
thyX3067531p.Ala139Ser0.689
thyX3067545p.Glu134Ala0.711
thyX3067549p.Thr133Ala0.865
thyX3067556p.His130Gln0.865
thyX3067559c.387G>C0.892
thyX3067565p.Asp127Glu0.900
thyX3067570p.Ala126Pro0.878
thyX3067577c.369C>T0.881
thyX3067602p.Arg115His0.868
thyX3067611p.Lys112Thr0.868
thyX3067619c.327T>G0.868
thyX3067631c.315G>C0.816
thyX3067634c.312G>C0.795
thyX3067652c.294A>G0.822
thyX3067661c.285G>C0.818
thyX3067685c.261T>G0.795
thyX3067693p.Ile85Leu0.788
thyX3067694c.252C>G0.788
thyX3067718c.228G>C0.844
thyX3067721c.225A>G0.844
thyX3067727c.219T>G0.794
thyX3067738p.Phe70Leu0.839
thyX3067739c.207A>G0.839
thyX3067762p.Arg62Lys0.767
thyX3067765p.Leu61Ile0.767
thyX3067772c.174G>C0.767
thyX3067781c.165G>C0.733
thyX3067793c.153A>G0.667
thyX3067799c.147C>T0.615
thyX3067802c.144G>C0.615
thyX3067814c.132A>G0.633
thyX3067850c.96T>G0.548
thyX3067869p.Thr26Ser0.463
thyX3067874c.72G>C0.463
thyX3067883c.63G>C0.447
thyX3067886c.60T>G0.444
thyX3067889c.57G>C0.432
thyX3067898p.Asp16Glu0.441
thyX3067935p.Thr4Ile0.455
thyA3073794c.678T>G0.636
thyA3073812c.660G>C0.867
thyA3073815c.657C>T0.871
thyA3073824c.648T>C0.882
thyA3073827c.645T>C0.882
thyA3073839c.633A>G0.895
thyA3073860c.612G>C0.900
thyA3073863c.609A>G0.897
thyA3073866c.606G>C0.889
thyA3073874p.Ile200Val0.889
thyA3073892c.580A>G0.875
thyA3073898p.Ala192Ser0.875
thyA3073917c.555G>C0.806
thyA3073920c.552G>C0.793
thyA3073925c.547C>T0.733
thyA3073929c.543A>G0.733
thyA3073947c.525C>T0.742
thyA3073953c.519A>G0.704
thyA3073956c.516C>G0.655
thyA3073959c.513A>G0.704
thyA3073977c.495T>C0.714
thyA3073989c.483A>G0.654
thyA3074004c.468A>G0.625
thyA3074010c.462G>C0.625
thyA3074028c.444C>G0.600
thyA3074031c.441A>G0.600
thyA3074037c.435G>C0.636
thyA3074053p.Arg140Gln0.611
thyA3074057p.Glu139Pro0.611
thyA3074061c.411T>C0.611
thyA3074079c.393C>G0.667
thyA3074097c.375G>C0.529
thyA3074102p.Asp124Asn0.529
thyA3074106c.366A>G0.529
thyA3074127c.345C>G0.556
thyA3074130c.342C>G0.500
thyA3074154c.318A>G0.538
thyA3074157c.315G>C0.500
thyA3074160c.312T>C0.500
thyA3074165p.Ala103Thr0.500
thyA3074172c.300C>G0.667
thyA3074175c.297T>C0.667
thyA3074181c.291T>C0.739
thyA3074187c.285A>G0.739
thyA3074205p.Glu89Asp0.708
thyA3074214c.258A>G0.630
thyA3074241c.231G>C0.556
thyA3074244c.228T>C0.536
thyA3074254p.His73Arg0.481
thyA3074262c.210A>G0.519
thyA3074267p.Ile69Val0.464
thyA3074268c.204A>G0.464
thyA3074285c.187A>G0.400
thyA3074286c.186A>G0.400
thyA3074334c.138A>G0.375
thyA3074346c.126G>A0.419
thyA3074349c.123A>G0.419
thyA3074360c.112A>G0.419
thyA3074361c.111A>G0.419
thyA3074364c.108A>G0.419
thyA3074372p.Met34Leu0.441
thyA3074377p.Gln32Arg0.417
thyA3074391c.81G>T0.474
thyA3074397c.75T>C0.474
thyA3074412c.60G>A0.475
thyA3074423p.Pro17Ala0.462
thyA3074427c.45A>T0.462
thyA3074432p.Thr14Glu0.462
thyA3074433p.Glu13Asp0.450
thyA3074444p.Phe10Leu0.474
thyA3074445c.27G>T0.462
thyA3074448c.24C>A0.475
thyA3074463c.9T>G0.533
thyA3074471p.Val1Pro0.565
ald3087272c.453A>C0.778
ald3087278p.Gln153His0.789
ald3087281c.462G>C0.789
ald3087284c.465C>G0.789
ald3087290c.471T>C0.750
ald3087305c.486G>C0.739
ald3087311c.492C>G0.615
ald3087318p.Glu167Lys0.593
ald3087344c.525C>G0.500
ald3087347c.528C>G0.500
ald3087350c.531C>T0.421
ald3087356c.537C>T0.389
ald3087368c.549A>G0.300
ald3087375p.Ile186Val0.300
ald3087380c.561C>G0.300
ald3087578c.759A>C0.379
ald3087590p.His257Gln0.393
ald3087596c.777A>G0.280
ald3087599c.780A>G0.320
ald3087602c.783T>C0.308
ald3087608c.789A>G0.308
ald3087614c.795G>C0.308
ald3087617c.798T>C0.333
ald3087620c.801A>C0.333
ald3087621p.Ala268Ser0.333
ald3087635c.816C>T0.400
ald3087641c.822T>C0.433
ald3087647c.828A>G0.433
ald3087649p.Gly277Asp0.433
ald3087653c.834A>G0.419
ald3087656c.837A>G0.452
ald3087665c.846C>G0.500
ald3087666p.Tyr283His0.500
ald3087672p.His285Asp0.562
ald3087680c.861G>C0.581
ald3087704c.885T>C0.541
ald3087716c.897G>C0.514
ald3087726p.Ala303Ser0.500
ald3087729p.Ser304Ala0.472
ald3087737c.918G>C0.459
ald3087749c.930C>G0.471
ald3087750p.Tyr311Val0.471
ald3087761c.942C>G0.471
ald3087770c.951G>C0.485
ald3087787p.Glu323Ala0.400
ald3087791c.972T>C0.400
ald3087797p.Asp326Glu0.387
ald3087799p.His327Arg0.387
ald3087821c.1002G>A0.345
ald3087825p.Asn336Asp0.357
ald3087829p.Pro337His0.357
ald3087833c.1014A>T0.385
ald3087836c.1017A>G0.400
ald3087845c.1026T>C0.370
ald3087860p.Glu347Asp0.318
ald3087869c.1050A>G0.190
fbiA3640278c.-265G>A0.188
fbiA3640291c.-252T>C0.650
fbiA3640301c.-242GTTAAC>G0.667
fbiA3640307c.-236C>A0.650
fbiA3640347c.-196A>G0.674
fbiA3640349c.-194A>G0.674
fbiA3640350c.-193C>T0.674
fbiA3640365c.-178C>G0.702
fbiA3640557c.15T>C0.743
fbiA3640562p.Ala7Val0.743
fbiA3640569c.27A>G0.722
fbiA3640572c.30C>T0.703
fbiA3640683c.141C>T0.294
fbiA3640689c.147C>T0.333
fbiA3640707c.165G>A0.316
fbiA3640713c.171T>A0.273
fbiA3640722c.180G>C0.273
fbiA3640726c.184C>T0.261
fbiA3640797c.255T>C0.231
fbiA3640808p.Met89Lys0.158
fbiA3640810p.Gln90Glu0.158
fbiA3640820p.Val93Ala0.143
fbiA3640827c.285T>C0.167
fbiA3640830c.288C>G0.240
fbiA3640839c.297C>G0.423
fbiA3640850p.Glu103Gly0.481
fbiA3640857c.315G>C0.520
fbiA3640866c.324T>C0.560
fbiA3640871p.Ala110Gly0.609
fbiA3640878c.336T>C0.710
fbiA3640899c.357G>C0.710
fbiA3640900p.Gln120Asn0.710
fbiA3640911c.369C>T0.733
fbiA3640914c.372C>G0.733
fbiA3640930p.Glu130Thr0.652
fbiA3640935c.393C>G0.625
fbiA3640938c.396A>G0.625
fbiA3640944c.402T>C0.625
fbiA3640953c.411A>G0.652
fbiA3640962c.420C>G0.200
fbiA3640974c.432T>C0.200
fbiA3640975p.Ala145Leu0.200
fbiA3641055c.513G>A0.158
fbiA3641073c.531T>C0.176
fbiA3641157p.Asp205Glu0.217
fbiA3641164p.Ile208Val0.217
fbiA3641170p.Met210Leu0.208
fbiA3641178c.636G>C0.208
fbiA3641184c.642T>G0.200
fbiA3641196c.654C>G0.200
fbiA3641200p.Ile220Val0.200
fbiA3641217c.675C>G0.238
fbiA3641226c.684G>C0.222
fbiA3641227p.Ile229Val0.222
fbiA3641234p.Ala231Gly0.222
fbiA3641239c.697T>C0.211
fbiA3641246p.Glu235Ala0.235
fbiA3641250c.708A>G0.250
fbiA3641252p.Thr237Lys0.250
fbiA3641256c.714A>C0.294
fbiA3641260p.Ile240Val0.294
fbiA3641286c.744C>T0.500
fbiA3641288p.Glu249Gly0.500
fbiA3641314p.Thr258Ala0.200
fbiA3641454c.912G>C0.273
fbiA3641490c.948G>C0.300
fbiA3641493c.951T>C0.273
fbiA3641502c.960T>C0.273
alr3840236c.1185T>G0.259
alr3840239c.1182C>G0.250
alr3840248c.1173G>C0.226
alr3840368c.1053G>T0.500
alr3840382p.Met347Val0.519
alr3840522p.Ile300Thr0.389
alr3840527c.894T>G0.389
alr3840536c.885A>G0.368
alr3840539c.882C>G0.389
alr3840547p.Gly292Ser0.400
alr3840551c.870C>G0.400
alr3840566c.855T>C0.400
alr3840575c.846C>T0.250
alr3840578c.843A>C0.235
alr3840583p.Ala280Pro0.235
alr3840584c.837A>G0.235
alr3840593c.828G>C0.250
alr3840602c.819C>G0.263
alr3840607p.Val272Ile0.263
alr3840611c.810C>T0.263
alr3840620c.801A>G0.278
alr3840627p.Ala265Glu0.312
alr3840632c.789T>C0.294
alr3840641c.780T>C0.294
alr3840647c.774A>G0.357
alr3840662c.759C>G0.312
alr3840665c.756C>G0.312
alr3840673p.Leu250Met0.333
alr3840926c.495A>G0.458
alr3840932c.489G>A0.458
alr3840944c.477A>G0.458
alr3840947c.474C>G0.458
alr3840959c.462C>G0.520
alr3840968c.453C>G0.538
alr3840980c.441C>G0.536
alr3840989c.432C>G0.536
alr3840994p.His143Asp0.536
alr3840997c.424C>G0.536
alr3841001c.420T>C0.556
alr3841010c.411T>C0.556
alr3841018p.Leu135Glu0.536
alr3841022c.399G>C0.536
alr3841028c.393C>G0.536
alr3841033p.Val130Ile0.517
alr3841039p.Val128Ile0.556
alr3841059p.Gly121Ala0.600
alr3841069p.Ile118Phe0.632
alr3841079c.342A>G0.641
alr3841100c.321T>C0.667
alr3841105p.Thr106Arg0.655
alr3841108p.Ile105Val0.655
alr3841112c.309A>G0.679
alr3841115c.306A>G0.679
alr3841127c.294T>C0.731
alr3841208c.213A>G0.182
alr3841214c.207G>C0.182
alr3841232c.189C>G0.182
alr3841306p.Met39Leu0.267
alr3841325c.96A>C0.267
alr3841332p.Gln30Leu0.188
panD4043867p.Gly139Arg0.676
panD4043872p.Gly137Val0.676
panD4043876p.Leu136Ile0.697
panD4043883c.399G>A0.676
panD4043886c.396T>C0.686
panD4043896p.Gly129Ala0.667
panD4043903p.Asn127Asp0.667
panD4043913c.369A>G0.649
panD4043916c.366T>C0.649
panD4043922c.360A>G0.615
panD4043933p.Met117Leu0.515
panD4043939p.Ile115Val0.548
panD4043951p.Tyr111Asp0.567
panD4043952c.330A>G0.567
panD4043961c.321A>G0.567
panD4043964c.318C>G0.567
panD4044057c.225G>T0.556
panD4044072c.210G>C0.667
panD4044075c.207A>G0.667
panD4044081c.201A>G0.667
panD4044084c.198A>G0.667
panD4044105c.177C>G0.688
panD4044117c.165C>G0.583
panD4044120c.162T>G0.583
panD4044123c.159A>G0.583
panD4044126c.156A>G0.583
panD4044138c.144A>G0.500
panD4044150c.132T>C0.500
panD4044165c.117C>G0.600
panD4044174c.108G>C0.600
embC4239994c.132C>G0.286
embC4240006c.144A>G0.308
embC4240019p.Asn53Asp0.308
embC4240033c.171G>C0.385
embC4240036c.174A>G0.385
embC4240037c.175T>C0.385
embC4240048c.186C>A0.500
embC4240051c.189A>G0.500
embC4240060c.198G>C0.545
embC4240065p.Ala68Gly0.545
embC4240069c.207T>C0.583
embC4240078c.216A>G0.545
embC4240081c.219G>C0.538
embC4240087c.225T>C0.538
embC4240090c.228C>T0.467
embC4240105c.243C>T0.389
embC4240123c.261C>G0.318
embC4240126c.264C>T0.318
embC4240178c.316T>C0.333
embC4240183c.321A>G0.333
embC4240204c.342T>C0.360
embC4240210c.348C>G0.360
embC4240216c.354T>C0.364
embC4240219c.357C>G0.381
embC4240222c.360G>C0.381
embC4240229p.Leu123Ile0.364
embC4240232p.Gln124Val0.364
embC4240249p.Asp129Glu0.400
embC4240258c.396T>G0.423
embC4240267c.405T>C0.407
embC4240270c.408T>C0.407
embC4240277p.Leu139Val0.393
embC4240282c.420C>G0.393
embC4240284p.Thr141Ser0.423
embC4240297c.435T>C0.444
embC4240313p.Thr151Ala0.448
embC4240318c.456T>C0.393
embC4240325c.463T>C0.393
embC4240330c.468A>G0.407
embC4240348c.486T>C0.429
embC4240354c.492C>G0.414
embC4240355p.Ala165Thr0.429
embC4240363c.501A>G0.429
embC4240372c.510A>C0.227
embC4240376p.Val172Thr0.227
embC4240391p.Ala177Ser0.250
embC4240399c.537C>T0.217
embC4240405c.543T>C0.227
embC4240406p.Ala182Ser0.227
embC4240417c.555C>G0.263
embC4240420c.558T>G0.263
embC4240424p.Arg188Lys0.263
embC4240444c.582C>G0.400
embC4240447c.585G>T0.400
embC4240459c.597G>C0.417
embC4240462c.600G>C0.435
embC4240471c.609C>T0.368
embC4240474c.612G>C0.318
embC4240475p.Ala205Ser0.318
embC4240484p.Ala208Thr0.318
embC4240489c.627A>G0.333
embC4240492c.630G>C0.333
embC4240495c.633T>G0.333
embC4240512p.Ser217Thr0.462
embC4240516c.654G>C0.462
embC4240519c.657T>C0.462
embC4240543c.681G>C0.500
embC4240558c.696C>G0.480
embC4240561c.699C>G0.458
embC4240570c.708C>G0.235
embC4240574p.Val238Leu0.235
embC4240578p.Ala239Val0.211
embC4240582c.720C>G0.222
embC4240587p.Gly242Ala0.222
embC4240592p.Ala244Ser0.222
embC4240600c.738G>C0.211
embC4240610p.Ile250Arg0.200
embC4240615c.753G>C0.231
embC4240630c.768C>A0.529
embC4240632p.Met257Thr0.529
embC4240642c.780G>C0.708
embC4240645c.783G>C0.759
embC4240651c.789G>A0.846
embC4240669c.807G>C0.857
embC4240671p.Thr270Ile0.857
embC4240677p.Gly272Ala0.800
embC4240685p.Thr275Ala0.848
embC4240693c.831T>G0.861
embC4240699c.837C>G0.861
embC4240726c.864G>C0.762
embC4240780c.918T>C0.767
embC4240783c.921G>C0.767
embC4240789c.927T>C0.773
embC4240819c.957A>G0.756
embC4240828c.966G>A0.737
embC4240831c.969T>G0.737
embC4240867c.1005T>C0.593
embC4240870c.1008T>C0.577
embC4240873c.1011C>G0.577
embC4240879c.1017G>C0.542
embC4240880p.Ala340Thr0.542
embC4240885c.1023T>C0.500
embC4240897c.1035C>G0.455
embC4240898c.1036C>T0.455
embC4240903c.1041C>G0.455
embC4240911p.Ala350Val0.571
embC4240921c.1059C>G0.533
embC4240924c.1062C>G0.533
embC4240936c.1074A>G0.484
embC4240945c.1083T>G0.500
embC4240954p.Ile364Met0.519
embC4240960c.1098G>C0.250
embC4240963c.1101G>C0.250
embC4240966c.1104G>C0.250
embC4240969c.1107C>T0.250
embC4240972c.1110C>G0.222
embC4240979p.Thr373Gln0.222
embC4240983p.Ser374Asn0.235
embC4240987c.1125G>C0.267
embC4240990c.1128A>G0.267
embC4240996c.1134G>C0.656
embC4241002c.1140G>C0.656
embC4241013p.Met384Thr0.688
embC4241017c.1155T>C0.676
embC4241023c.1161T>G0.758
embC4241032c.1170G>C0.788
embC4241038c.1176G>C0.794
embC4241047c.1185C>G0.788
embC4241050c.1188T>G0.788
embC4241053c.1191G>C0.765
embC4241089c.1227C>G0.780
embC4241095c.1233C>T0.780
embC4241107c.1245G>C0.750
embC4241140c.1278A>G0.778
embC4241146c.1284C>G0.756
embC4241158c.1296T>C0.732
embC4241161c.1299C>G0.707
embC4241162c.1300T>C0.707
embC4241170c.1308G>C0.750
embC4241173c.1311C>T0.750
embC4241203c.1341T>C0.762
embC4241206c.1344G>C0.762
embC4241218c.1356G>C0.780
embC4241230c.1368A>G0.756
embC4241233c.1371G>C0.769
embC4241301p.Ala480Val0.375
embC4241314c.1452G>C0.333
embC4241319p.Pro486Leu0.333
embC4241326c.1464T>C0.222
embC4241329c.1467T>C0.222
embC4241332c.1470T>C0.222
embC4241338c.1476C>G0.222
embC4241339p.Phe493Leu0.222
embC4241344c.1482G>C0.200
embC4241351p.Ile497Val0.429
embC4241361p.Asn500Thr0.414
embC4241363p.Leu501Met0.414
embC4241374c.1512T>C0.464
embC4241380c.1518A>C0.464
embC4241383c.1521G>C0.464
embC4241392c.1530G>C0.481
embC4241394p.Lys511Ser0.481
embC4241449c.1587C>G0.727
embC4241453p.Ile531Val0.710
embC4241479c.1617C>G0.714
embC4241480c.1618T>C0.677
embC4241488c.1626G>C0.667
embC4241496p.Ala545Gly0.680
embC4241500c.1638A>C0.680
embC4241501p.Ser547Thr0.680
embC4241506c.1644G>C0.720
embC4241518c.1656A>G0.667
embC4241521c.1659T>C0.640
embC4241530c.1668C>A0.680
embC4241536c.1674A>G0.680
embC4241539c.1677T>C0.680
embC4241545c.1683T>C0.704
embC4241551c.1689A>G0.714
embC4241567p.Ile569Val0.737
embC4241572c.1710C>G0.750
embC4241578c.1716G>C0.737
embC4241584c.1722T>C0.684
embC4241587c.1725C>G0.714
embC4241591p.Leu577Val0.727
embC4241611c.1749G>C0.696
embC4241614c.1752A>C0.682
embC4241626c.1764T>C0.696
embC4241635c.1773G>C0.640
embC4241644c.1782G>C0.667
embC4241648c.1786T>C0.667
embC4241657p.Ser599Pro0.667
embC4241665c.1803G>C0.654
embC4241671c.1809T>C0.654
embC4241689c.1827G>C0.444
embC4241691p.Gly610Ala0.444
embC4241694p.Ala611Val0.471
embC4241698c.1836G>C0.526
embC4241704c.1842C>G0.556
embC4241707c.1845G>A0.556
embC4241713c.1851G>C0.625
embC4241719c.1857G>C0.625
embC4241727p.Phe622Tyr0.733
embC4241741p.Val627Leu0.733
embC4241747p.Val629Leu0.733
embC4241750p.Leu630Val0.733
embC4241755c.1893C>G0.733
embC4241770c.1908T>C0.703
embC4241791c.1929G>C0.595
embC4241794c.1932C>G0.595
embC4241797c.1935C>T0.595
embC4241809c.1947A>C0.556
embC4241995c.2133C>G0.526
embC4242002p.Leu714Val0.526
embC4242011p.Leu717Val0.526
embC4242024p.Val721Ala0.588
embC4242036p.Gln725Leu0.625
embC4242045p.Ile728Thr0.455
embC4242047p.Ser729Asp0.455
embC4242055c.2193C>T0.455
embC4242061c.2199G>C0.500
embC4242067c.2205G>C0.455
embC4242070c.2208T>C0.455
embC4242076c.2214G>C0.357
embC4242079c.2217T>C0.357
embC4242085c.2223A>G0.417
embC4242091c.2229T>G0.455
embC4242092c.2230T>C0.455
embC4242095p.Ala745Thr0.500
embC4242106c.2244C>G0.750
embC4242121c.2259A>G0.692
embC4242127c.2265G>T0.654
embC4242138p.Leu759Gln0.615
embC4242142c.2280T>C0.615
embC4242145c.2283C>G0.615
embC4242151c.2289A>G0.593
embC4242160c.2298G>C0.520
embC4242161p.Ala767Ser0.520
embC4242170p.Thr770Gly0.522
embC4242175c.2313G>C0.571
embC4242176p.Pro772Ser0.571
embC4242179p.Leu773Ala0.571
embC4242184c.2322C>G0.571
embC4242193c.2331G>C0.609
embC4242196c.2334A>C0.609
embC4242208c.2346T>G0.577
embC4242220c.2358A>G0.625
embC4242229c.2367C>A0.640
embC4242245p.Thr795Arg0.415
embC4242519p.Thr886Ser0.176
embC4242532c.2670A>T0.294
embC4242539p.Ser893Pro0.278
embC4242550c.2688C>G0.733
embC4242552p.Arg897Gln0.267
embC4242554p.Leu898Val0.267
embC4242573p.Glu904Ala0.231
embC4242577c.2715A>G0.273
embC4242583c.2721C>G0.300
embC4242585p.Ala908Gly0.300
embC4242589c.2727A>G0.273
embC4242594p.His911Pro0.273
embC4242598c.2736T>C0.273
embC4242601c.2739G>C0.273
embC4242605p.Met915Phe0.273
embC4242608p.Glu916Gln0.273
embC4242631c.2769G>C0.250
embC4242643c.2781C>T0.588
embC4242653p.Ala931Leu0.231
embC4242656p.Pro932Ala0.231
embC4242664c.2802C>G0.231
embC4242667c.2805C>G0.231
embC4242673c.2811G>C0.214
embC4242674p.Ser938Gly0.214
embC4242677p.Thr939Ser0.214
embC4242689p.Val943Ile0.618
embC4242694c.2832G>A0.600
embC4242710p.Gln950Glu0.651
embC4242715c.2853T>C0.651
embC4242742c.2880C>G0.622
embC4242748c.2886A>G0.650
embC4242754c.2892G>C0.659
embC4242764p.Val968Leu0.682
embC4242779p.Asn973Asp0.659
embC4242791p.Ala977Ser0.634
embC4242796c.2934G>C0.634
embC4242799c.2937T>C0.634
embC4242820c.2958G>C0.605
embC4242823c.2961G>C0.622
embC4242832c.2970A>C0.622
embC4242838c.2976C>G0.595
embC4242841c.2979C>T0.579
embC4242844c.2982A>G0.579
embC4242847c.2985C>A0.579
embC4242859c.2997C>T0.595
embC4242862c.3000A>G0.595
embC4242863p.Tyr1001Asn0.595
embC4242883c.3021C>G0.595
embC4242892c.3030G>C0.512
embC4242901c.3039G>C0.568
embC4242919c.3057A>G0.471
embC4242928c.3066A>G0.433
embC4242931c.3069G>C0.448
embC4242940c.3078T>C0.444
embC4242941p.His1027Asn0.444
embC4242946c.3084T>C0.440
embC4242952c.3090T>C0.478
embC4242965p.Ile1035Val0.458
embA4243218c.-15C>T0.667
embA4243222c.-11C>G0.667
embA4243245p.Gly5Arg0.783
embA4243412c.180C>G0.222
embA4243415c.183T>C0.235
embA4243421c.189A>G0.211
embA4243424c.192C>G0.222
embA4243433c.201A>C0.222
embA4243451c.219G>C0.250
embA4243454c.222C>T0.250
embA4243461p.Ser77Pro0.250
embA4243465p.Ala78Asp0.250
embA4243472c.240C>G0.211
embA4243475c.243G>C0.211
embA4243553c.321C>G0.429
embA4243559c.327C>G0.429
embA4243563p.Gln111Lys0.429
embA4243569p.Thr113Val0.400
embA4243736c.504A>T0.400
embA4243742c.510T>C0.400
embA4243748c.516C>G0.385
embA4244189c.957C>G0.273
embA4244192c.960C>G0.286
embA4244207c.975C>G0.261
embA4244298p.Ser356Ala0.273
embA4244306c.1074G>C0.273
embA4244340p.Ser370Ala0.300
embA4244366c.1134C>G0.700
embA4244372c.1140T>G0.684
embA4244378c.1146G>A0.684
embA4244390c.1158G>C0.571
embA4244393c.1161G>C0.571
embA4244396c.1164T>C0.571
embA4244399c.1167G>C0.615
embA4244408c.1176G>C0.571
embA4244412p.Val394Met0.571
embA4244415c.1183T>C0.571
embA4244420c.1188G>C0.571
embA4244426c.1194G>C0.571
embA4244427p.Ser399Ala0.533
embA4244435c.1203G>C0.500
embA4244438c.1206C>G0.500
embA4244439p.Gly403Arg0.500
embA4244447c.1215G>C0.650
embA4244462c.1230A>G0.652
embA4244478p.Thr416Leu0.636
embA4244483c.1251T>G0.652
embA4244485p.Thr418Ser0.652
embA4244491p.Thr420Met0.704
embA4244498c.1266A>G0.704
embA4244507c.1275G>T0.625
embA4244508c.1276T>C0.625
embA4244516c.1284G>C0.639
embA4244517p.Leu429Val0.639
embA4244523p.Pro431Ala0.667
embA4244534c.1302T>C0.674
embA4244537c.1305T>G0.674
embA4244543c.1311C>G0.700
embA4244547p.Ile439Val0.700
embA4244552c.1320C>G0.700
embA4244557p.Arg442Thr0.700
embA4244567c.1335C>T0.714
embA4244576c.1344G>A0.707
embA4244582c.1350T>C0.725
embA4244585c.1353A>G0.718
embA4244611p.Ala460Gly0.541
embA4244616p.Ala462Ser0.720
embA4244619c.1387T>C0.720
embA4244625p.Leu465Val0.692
embA4244631p.Thr467Leu0.692
embA4244645c.1413T>C0.680
embA4244648c.1416G>C0.680
embA4244649p.Asp473Ser0.680
embA4244670p.Ala480Leu0.700
embA4244675c.1443A>G0.700
embA4244678c.1446G>C0.737
embA4244681c.1449A>C0.737
embA4244690c.1458G>A0.786
embA4244702c.1470C>G0.733
embA4244708c.1476C>G0.727
embA4244728p.Phe499Trp0.741
embA4244747c.1515T>C0.200
embA4244750c.1518C>G0.200
embA4244885c.1653A>G0.545
embA4244897c.1665T>C0.429
embA4244900c.1668G>C0.429
embA4244904p.Val558Ile0.455
embA4244918c.1686G>C0.500
embA4244919p.Leu563Val0.500
embA4244930c.1698G>C0.435
embA4244933c.1701A>G0.417
embA4244936c.1704C>G0.417
embA4244945c.1713C>G0.435
embA4244946p.Val572Ile0.435
embA4244957c.1725C>T0.417
embA4244960c.1728A>C0.417
embA4244966c.1734C>G0.417
embA4244980p.Val583Ala0.500
embA4244982c.1750T>C0.474
embA4244987c.1755T>C0.474
embA4245041c.1809C>G0.676
embA4245044c.1812G>C0.686
embA4245053c.1821G>C0.707
embA4245060c.1828T>C0.767
embA4245083c.1851A>C0.767
embA4245089c.1857G>C0.744
embA4245092c.1860C>G0.744
embA4245101c.1869G>C0.750
embA4245137c.1905T>C0.750
embA4245146c.1914G>A0.775
embA4245149c.1917C>T0.775
embA4245153p.Ile641Val0.769
embA4245182c.1950T>C0.804
embA4245189c.1957C>T0.804
embA4245198p.Leu656Ile0.771
embA4245207c.1975T>C0.804
embA4245215c.1983A>C0.778
embA4245222p.Tyr664Gln0.733
embA4245248c.2016G>C0.717
embA4245257c.2025A>G0.705
embA4245263c.2031A>G0.727
embA4245282p.Ile684Val0.632
embA4245285c.2053T>C0.622
embA4245290c.2058C>G0.605
embA4245293c.2061T>G0.605
embA4245296c.2064G>C0.605
embA4245299c.2067A>G0.605
embA4245315p.Val695Thr0.588
embA4245328p.Ala699Val0.636
embA4245335c.2103A>G0.656
embA4245340p.Gly703Ala0.688
embA4245345p.Met705Leu0.697
embA4245348p.Ala706Thr0.706
embA4245355p.Ala708Gly0.714
embA4245368c.2136T>C0.771
embA4245377c.2145T>C0.758
embA4245388p.Ala719Gly0.778
embA4245401c.2169G>C0.750
embA4245408p.Leu726Ile0.667
embA4245412p.Ser727Thr0.667
embA4245414p.Thr728Ser0.667
embA4245419c.2187G>C0.667
embA4245431c.2199T>C0.704
embA4245434c.2202G>C0.704
embA4245470c.2238T>C0.731
embA4245473c.2241C>G0.720
embA4245483p.Gln751Ala0.632
embA4245490p.Val753Ala0.571
embA4245501p.Ala757Thr0.571
embA4245509c.2277A>G0.571
embA4245512c.2280G>C0.571
embA4245518c.2286A>G0.571
embA4245524c.2292G>C0.545
embA4245527c.2295C>G0.545
embA4245530c.2298T>C0.500
embA4245531p.Ile767Val0.500
embA4245535p.Ser768Asn0.462
embA4245539c.2307C>G0.480
embA4245542c.2310C>G0.500
embA4245557c.2325G>A0.500
embA4245575c.2343C>G0.444
embA4245576p.Lys782Gln0.444
embA4245593c.2361C>G0.350
embA4245594p.Ser788Thr0.350
embA4245599c.2367A>G0.350
embA4245602c.2370C>G0.350
embA4245605c.2373G>A0.350
embA4245620c.2388T>C0.235
embA4245623c.2391G>C0.188
embA4245626c.2394G>C0.188
embA4245629c.2397C>G0.188
embA4245635c.2403A>G0.176
embA4245638c.2406C>G0.176
embA4245648p.Ile806Tyr0.167
embA4245652p.Thr807Ser0.167
embA4245659c.2427C>G0.320
embA4245674c.2442A>C0.407
embA4245677c.2445G>C0.407
embA4245693p.Ile821Val0.458
embA4245701c.2469G>C0.417
embA4245704c.2472G>C0.417
embA4245725c.2493A>G0.385
embA4245726c.2494T>C0.360
embA4245737c.2505A>C0.375
embA4245740c.2508T>C0.391
embA4245741p.Thr837Ala0.375
embA4245764c.2532G>C0.375
embA4245772p.Asn847Thr0.423
embA4245785c.2553G>C0.448
embA4245807c.2575T>C0.318
embA4245812c.2580G>C0.350
embA4245813p.Pro861Ala0.350
embA4245820p.Ser863Thr0.350
embA4245824c.2592G>C0.368
embA4245833c.2601G>C0.500
embA4245842c.2610G>C0.500
embA4245845c.2613T>C0.500
embA4245851c.2619G>C0.500
embA4245860c.2628C>G0.500
embA4245885p.Asp885Thr0.429
embA4245892p.Ile887Thr0.409
embA4245899c.2667C>G0.391
embA4245902c.2670G>A0.391
embA4245905c.2673C>G0.391
embA4245911c.2679A>G0.450
embA4245917c.2685G>A0.429
embA4245930p.Gly900Arg0.333
embA4245983c.2751A>C0.545
embA4245989c.2757A>G0.600
embA4245992c.2760C>G0.632
embA4246004c.2772T>C0.600
embA4246010c.2778G>T0.600
embA4246013c.2781T>C0.600
embA4246022c.2790C>G0.632
embA4246040c.2808C>G0.611
embA4246041p.Asp937Asn0.611
embA4246055c.2823T>C0.571
embA4246064c.2832T>C0.545
embA4246080p.Pro950Ser0.571
embA4246088c.2856A>G0.571
embA4246097c.2865C>G0.545
embA4246103c.2871C>G0.524
embA4246109c.2877C>G0.550
embA4246115c.2883T>G0.500
embA4246128p.Ser966Thr0.429
embA4246138p.Arg969Gln0.400
embA4246140c.2908T>C0.400
embA4246143p.Ile971Val0.400
embA4246151c.2919A>G0.400
embA4246152p.Ala974Gln0.400
embA4246157c.2925A>G0.375
embA4246164c.2932T>C0.550
embA4246184c.2952A>C0.579
embA4246196c.2964C>G0.636
embA4246205c.2973A>G0.600
embA4246211c.2979T>C0.600
embA4246217c.2985G>A0.556
embA4246220c.2988T>C0.556
embA4246223c.2991C>T0.556
embA4246227p.Ile999Val0.579
embA4246235c.3003G>A0.632
embA4246242p.Gln1004Gly0.632
embA4246250c.3018G>C0.571
embA4246256c.3024G>T0.571
embA4246259c.3027G>C0.619
embA4246264p.His1011Arg0.619
embA4246292c.3060A>G0.692
embA4246305p.Ser1025Glu0.667
embA4246308p.Thr1026Ala0.667
embA4246316c.3084T>G0.739
embA4246319c.3087G>C0.731
embA4246329p.Thr1033Ala0.739
embA4246349c.3117C>G0.808
embA4246359p.Ala1043Ser0.792
embA4246367c.3135C>T0.679
embA4246373c.3141T>C0.679
embA4246376c.3144G>C0.679
embA4246379c.3147C>T0.679
embA4246400c.3168G>C0.667
embA4246413p.His1061Phe0.708
embA4246419c.3187C>T0.680
embB4246594c.81C>T0.483
embB4246603c.90C>G0.483
embB4246615c.102G>C0.483
embB4246621c.108T>C0.483
embB4246624c.111C>G0.483
embB4246627c.114T>C0.483
embB4246631c.118T>C0.483
embB4246636c.123G>C0.483
embB4246639c.126G>C0.483
embB4246642c.129G>C0.483
embB4246645c.132G>C0.483
embB4246669c.156C>G0.533
embB4246869p.Ser119Asn0.333
embB4246872p.Ala120Gly0.333
embB4246874p.Gln121Lys0.333
embB4246882c.369G>C0.333
embB4246900c.387C>T0.333
embB4247050c.537C>G0.353
embB4247059c.546C>A0.364
embB4247068c.555T>C0.364
embB4247074c.561G>T0.364
embB4247095c.582G>T0.267
embB4247098c.585C>G0.267
embB4247101c.588G>C0.267
embB4247105p.Pro198Ala0.267
embB4247110c.597G>C0.267
embB4247111c.598C>T0.267
embB4247114p.Ala201Thr0.267
embB4247117p.Val202Leu0.267
embB4247317c.804G>C0.412
embB4247326c.813A>G0.412
embB4247328p.Ser272Asn0.412
embB4247338c.825C>G0.435
embB4247347c.834G>C0.417
embB4247348p.Thr279Ala0.417
embB4247355p.Ala281Val0.385
embB4247358p.Val282Ala0.385
embB4247365c.852A>C0.393
embB4247371c.858C>G0.379
embB4247375p.Leu288Val0.379
embB4247386c.873T>C0.455
embB4247389c.876C>G0.455
embB4247395c.882C>G0.471
embB4247401c.888T>C0.471
embB4247407c.894G>C0.471
embB4247425c.912G>C0.462
embB4247434c.921C>G0.436
embB4247437c.924A>G0.459
embB4247440c.927C>G0.459
embB4247446c.933C>T0.486
embB4247464c.951C>G0.543
embB4247470c.957T>C0.529
embB4247491c.978G>C0.531
embB4247497c.984T>C0.548
embB4247512c.999T>C0.562
embB4247539c.1026T>C0.536
embB4247554c.1041T>C0.455
embB4247566c.1053C>A0.500
embB4247572c.1059A>G0.500
embB4247579p.Ala356Phe0.429
embB4247587c.1074G>A0.423
embB4247603c.1090C>T0.500
embB4247611c.1098G>T0.500
embB4247614c.1101T>C0.455
embB4247629c.1116C>G0.424
embB4247632c.1119C>G0.424
embB4247638c.1125G>T0.452
embB4247646p.Glu378Ala0.385
embB4247656c.1143A>G0.385
embB4247659c.1146C>G0.385
embB4247662c.1149C>G0.385
embB4247683c.1170C>G0.517
embB4247692c.1179C>G0.593
embB4247716c.1203C>T0.533
embB4247722c.1209G>C0.533
embB4247725c.1212G>C0.533
embB4247729p.Gly406Pro0.552
embB4247746c.1233C>T0.583
embB4247761c.1248T>C0.524
embB4247773c.1260G>A0.537
embB4247776c.1263G>T0.535
embB4247797c.1284C>G0.590
embB4247800c.1287A>T0.575
embB4247803c.1290G>C0.575
embB4247815c.1302C>G0.553
embB4247819p.Val436Ile0.526
embB4247830c.1317A>G0.558
embB4247836c.1323A>G0.537
embB4247839c.1326G>C0.524
embB4247866c.1353G>C0.605
embB4247875c.1362G>C0.595
embB4247876c.1363C>T0.595
embB4247881c.1368G>C0.634
embB4247887c.1374C>T0.643
embB4247893c.1380C>T0.615
embB4247899p.Met462Ile0.619
embB4247905c.1392G>C0.619
embB4247909c.1396T>C0.636
embB4247914c.1401G>C0.628
embB4247932c.1419C>G0.566
embB4247940p.Leu476Trp0.569
embB4247945c.1432T>C0.569
embB4247951p.Ser480Ala0.569
embB4247956c.1443G>C0.558
embB4247974c.1461C>G0.627
embB4248007c.1494C>G0.600
embB4248011p.Ser500Arg0.605
embB4248014p.Thr501Ala0.634
embB4248035p.Val508Ile0.769
embB4248040c.1527C>G0.769
embB4248041p.Ala510Thr0.769
embB4248044p.Lys511Ala0.769
embB4248070c.1557T>C0.750
embB4248085c.1572T>C0.659
embB4248097c.1584C>G0.615
embB4248130c.1617G>C0.579
embB4248142c.1629T>C0.564
embB4248143c.1630T>C0.564
embB4248157c.1644A>G0.583
embB4248172c.1659G>C0.522
embB4248199c.1686A>G0.463
embB4248200p.Ile563Val0.442
embB4248205c.1692C>G0.432
embB4248206p.Ser565Gly0.432
embB4248220c.1707A>C0.468
embB4248304c.1791G>C0.644
embB4248316c.1803C>G0.628
embB4248319c.1806A>G0.628
embB4248343c.1830G>C0.667
embB4248350c.1837T>C0.590
embB4248355c.1842A>G0.561
embB4248358c.1845C>G0.550
embB4248361c.1848A>C0.550
embB4248362p.Ser617Ala0.550
embB4248373c.1860C>G0.685
embB4248382c.1869C>G0.712
embB4248386c.1873C>A0.712
embB4248407p.Leu632Val0.605
embB4248410p.Phe633Leu0.605
embB4248419p.Leu636Met0.619
embB4248425c.1912T>C0.634
embB4248430c.1917T>C0.634
embB4248432p.Trp640Phe0.634
embB4248457c.1944T>C0.732
embB4248472c.1959T>C0.741
embB4248475c.1962G>C0.741
embB4248504p.Asp664Gly0.690
embB4248508c.1995G>A0.678
embB4248512p.Thr667Ser0.690
embB4248535c.2022C>G0.714
embB4248659p.Ala716Leu0.353
embB4248668p.Val719Ile0.400
embB4248676c.2163C>G0.375
embB4248688c.2175G>C0.412
embB4248697c.2184A>C0.412
embB4248706c.2193G>C0.467
embB4248720p.Gly736Ala0.357
embB4248725p.Ser738Asp0.312
embB4248731p.Val740Leu0.312
embB4248736c.2223G>C0.312
embB4248738p.Ala742Glu0.312
embB4248742c.2229T>C0.312
embB4248743p.Val744Ser0.312
embB4248748c.2235C>G0.208
embB4248757c.2244A>C0.269
embB4248772c.2259A>G0.364
embB4248943c.2430C>A0.444
embB4248961c.2448T>C0.500
embB4248980p.Ser823Ala0.167
embB4248985c.2472T>G0.182
embB4248994c.2481T>C0.182
embB4248997c.2484T>C0.182
embB4249000c.2487T>G0.182
embB4249018c.2505T>C0.182
embB4249048c.2535A>C0.167
embB4249135c.2622G>C0.533
embB4249138c.2625C>G0.516
embB4249145p.Thr878Ser0.516
embB4249153c.2640G>C0.516
embB4249164p.Ala884Asp0.559
embB4249259p.Met916Leu0.333
embB4249268p.Asp919Tyr0.400
embB4249276c.2763A>G0.556
embB4249277p.Tyr922Asn0.556
embB4249282c.2769A>C0.588
embB4249291c.2778C>A0.667
embB4249297c.2784G>C0.769
embB4249312c.2799C>T0.667
embB4249321c.2808A>C0.500
embB4249322p.Ala937Ser0.500
embB4249325p.Lys938Asp0.500
embB4249333c.2820C>G0.385
embB4249336c.2823C>G0.385
embB4249339c.2826T>C0.385
embB4249342c.2829C>G0.385
embB4249348c.2835G>C0.385
embB4249351c.2838C>G0.385
embB4249369c.2856T>C0.467
embB4249375c.2862G>C0.500
embB4249381c.2868A>G0.500
embB4249384c.2871G>T0.500
embB4249417c.2904A>G0.455
embB4249423p.Asp970Glu0.400
embB4249424p.Leu971Met0.400
embB4249429c.2916C>T0.368
embB4249432c.2919A>G0.400
embB4249441c.2928A>G0.471
embB4249444c.2931T>C0.533
embB4249469p.Leu986Met0.643
embB4249486c.2973T>G0.692
embB4249498c.2985G>C0.714
embB4249521p.Ala1003Val0.692
embB4249525c.3012T>C0.667
embB4249529p.Ile1006Val0.667
embB4249532p.Ala1007Thr0.667
embB4249537c.3024A>G0.667
embB4249543c.3030G>C0.667
embB4249546c.3033G>A0.667
embB4249558c.3045A>C0.714
embB4249568p.Ser1019Thr0.692
embB4249573c.3060T>C0.692
embB4249580p.Leu1023Met0.692
embB4249594c.3081G>C0.571
embB4249606c.3093C>A0.571
embB4249609c.3096T>C0.571
embB4249615c.3102C>G0.348
embB4249618c.3105C>G0.348
embB4249624c.3111C>G0.292
embB4249627c.3114G>C0.292
embB4249640c.3127T>C0.500
embB4249657c.3144C>G0.429
embB4249661p.Ala1050Ser0.429
embB4249666c.3153C>G0.429
embB4249677p.Arg1055His0.467
embB4249686p.Ala1058Gly0.467
embB4249693c.3180T>C0.467
embB4249699c.3186T>G0.467
embB4249702c.3189C>G0.429
embB4249711c.3198G>A0.429
ethA4326057p.Ile473Val0.294
ethA4326307c.1167G>C0.738
ethA4326310c.1164A>G0.732
ethA4326438p.Leu346Met0.500
ethA4326445c.1029C>T0.412
ethA4326457c.1017A>G0.389
ethA4326836p.Val213Gly0.556
ethA4326847c.627G>C0.636
ethA4326850c.624T>C0.677
ethA4327396c.78A>G0.795
ethA4327399p.Asp25Glu0.795
ethA4327423c.51G>C0.763
ethA4327435c.39T>G0.735
ethA4327438c.36A>G0.735
ethR4327746c.198A>G0.654
ethR4327755p.Glu69Asp0.640
ethR4327765p.Leu73Phe0.286
ethR4327862p.Thr105Ile0.294
ethR4328004c.456G>A1.000
gid4407603c.600C>T0.706
gid4407609c.594C>G0.706
gid4407652p.Val184Ala0.697
gid4407654c.549C>G0.733
gid4407668p.Ile179Ala0.731
gid4407762c.441T>C0.417
gid4407770c.433A>G0.417
gid4407771c.432C>T0.417
gid4407783c.420G>C0.385
gid4407786c.417C>A0.385
gid4407792c.411C>T0.417
gid4407798c.405C>G0.417

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;