TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5d66a021d61db
Sample: 5d66a021d61db

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Summary
ID: 5d66a021d61db
Date: Wed Aug 28 16:41:25 2019
Strain: lineage4.3;lineage4.1.2;lineage4.1.1;lineage2.2.1
Drug-resistance: Drug-resistant

Drug1ResistanceSupporting Mutations (frequency)
IsoniazidRkatG c.374 375insAG (0.93)
Rifampicin
EthambutolRembB p.His312Arg (1.00), embB p.Leu359Ile (0.92), embB p.Tyr384Asn (0.92), embB p.Ala388Gly (1.00), embB p.Asn399Asp (1.00), embB p.Ala659Thr (0.98)
Pyrazinamide
StreptomycinRrrs r.462c>t (0.94)
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5314c.75C>G1.000
gyrB5326c.87T>C1.000
gyrB5341c.102T>C1.000
gyrB5347c.108G>C1.000
gyrB5353c.114T>C1.000
gyrB5371c.132T>C1.000
gyrB5377c.138T>C1.000
gyrB5396p.Ala53Ser1.000
gyrB5407c.168G>A1.000
gyrB5614c.375G>C1.000
gyrB5623c.384T>C1.000
gyrB5632c.393A>G1.000
gyrB5638c.399C>T1.000
gyrB5772p.Ala178Asp0.958
gyrB5774p.Val179Ile0.958
gyrB5782c.543A>G0.964
gyrB5788c.549G>C0.967
gyrB5791c.552A>G0.967
gyrB5806c.567C>G0.976
gyrB5809c.570C>G0.974
gyrB5815c.576C>G0.952
gyrB5824c.585A>G0.951
gyrB5827c.588G>A0.952
gyrB5848c.609G>C0.944
gyrB5863c.624G>C0.923
gyrB5873c.634A>C0.960
gyrB5882p.Gln215Asn0.947
gyrB5887p.Asp216Glu0.950
gyrB5902c.663A>G0.909
gyrB5992c.753T>C0.957
gyrB5998c.759T>C0.957
gyrB6001c.762G>C0.957
gyrB6004c.765T>C0.957
gyrB6013c.774G>C0.964
gyrB6022c.783G>C0.964
gyrB6034c.795C>T0.963
gyrB6086p.Thr283Pro1.000
gyrB6091c.852G>C1.000
gyrB6100c.861G>C1.000
gyrB6115c.876A>G1.000
gyrB6123p.Ala295Gly1.000
gyrB6127c.888G>C1.000
gyrB6130c.891T>C1.000
gyrB6133c.894G>C1.000
gyrB6136c.897G>A1.000
gyrB6169c.930C>G1.000
gyrB6190c.951A>G1.000
gyrB6214c.975G>C1.000
gyrB6217c.978G>C1.000
gyrB6223c.984G>C1.000
gyrB6242p.Arg335Lys1.000
gyrB6250c.1011A>G0.964
gyrB6253c.1014G>C0.966
gyrB6274c.1035C>G0.976
gyrB6280c.1041T>C0.976
gyrB6286c.1047T>C0.975
gyrB6292c.1053G>C0.971
gyrB6295c.1056A>G0.971
gyrB6298c.1059C>T0.971
gyrB6299c.1060C>T0.971
gyrB6307c.1068T>G0.977
gyrB6319c.1080G>C1.000
gyrB6325c.1086C>G1.000
gyrB6361c.1122G>A1.000
gyrB6362c.1123T>C1.000
gyrB6379c.1140C>G1.000
gyrB6382c.1143A>G1.000
gyrB6388c.1149T>C1.000
gyrB6400c.1161C>G1.000
gyrB6403c.1164T>C1.000
gyrB6415c.1176G>C1.000
gyrB6427c.1188T>C1.000
gyrB6440p.Thr401Ala1.000
gyrB6448c.1209G>C1.000
gyrB6455p.Val406Ile1.000
gyrB6460c.1221G>C1.000
gyrB6469c.1230T>G1.000
gyrB6472c.1233G>T1.000
gyrB6475c.1236C>A1.000
gyrB6478c.1239G>A1.000
gyrB6484c.1245A>G1.000
gyrB6487c.1248C>G1.000
gyrB6490c.1251T>C1.000
gyrB6496c.1257G>C1.000
gyrB6499c.1260A>G1.000
gyrB6502c.1263T>C1.000
gyrB6508c.1269A>G1.000
gyrB6523c.1284G>C1.000
gyrB6526c.1287T>C1.000
gyrB6535c.1296C>A1.000
gyrB6542p.Ile435Leu1.000
gyrB6547c.1308T>C1.000
gyrB6550c.1311A>G1.000
gyrB6551c.1312T>C1.000
gyrB6565c.1326G>C1.000
gyrB6571c.1332T>C1.000
gyrB6577c.1338T>G1.000
gyrB6580c.1341C>G1.000
gyrB6583c.1344G>C1.000
gyrB6586c.1347T>C1.000
gyrB6598c.1359C>G1.000
gyrB6602c.1363C>T1.000
gyrB6610c.1371C>G1.000
gyrB6613c.1374A>C1.000
gyrB6616c.1377A>G1.000
gyrB6634c.1395T>C1.000
gyrB6637c.1398T>G1.000
gyrB6640c.1401A>G1.000
gyrB6649c.1410T>C1.000
gyrB6652c.1413C>G1.000
gyrB6655c.1416T>C1.000
gyrB6670c.1431G>C1.000
gyrB6673c.1434A>C1.000
gyrB6700c.1461T>C1.000
gyrB6703c.1464G>C1.000
gyrB6706c.1467G>A1.000
gyrB6709c.1470A>G1.000
gyrB6712c.1473G>C1.000
gyrB6730c.1491A>G1.000
gyrB6742c.1503A>G1.000
gyrB6745c.1506T>G1.000
gyrB6760c.1521G>C1.000
gyrB6778c.1539C>T1.000
gyrB6793c.1554T>C1.000
gyrB6797p.Gly520Thr1.000
gyrB6824c.1585C>T1.000
gyrB6841c.1602T>C1.000
gyrB6844c.1605T>G1.000
gyrB6853c.1614A>G1.000
gyrB6856c.1617T>C1.000
gyrB6859c.1620T>C1.000
gyrB6862c.1623C>G1.000
gyrB6878c.1639T>C1.000
gyrB6881c.1642T>C1.000
gyrB6904c.1665C>G1.000
gyrB6910c.1671G>A1.000
gyrB6911p.Asn558His1.000
gyrB6919c.1680T>C1.000
gyrB6925c.1686T>C1.000
gyrB6931c.1692A>C1.000
gyrB6934c.1695A>G1.000
gyrB6937c.1698G>A1.000
gyrB6949c.1710A>G0.909
gyrB6952c.1713C>G0.905
gyrB6955c.1716G>A0.905
gyrB6967c.1728T>C0.909
gyrB6970c.1731C>T0.909
gyrB6973c.1734G>C0.909
gyrB6976c.1737A>G0.909
gyrB6982c.1743A>C0.931
gyrB7000c.1761C>G0.938
gyrB7006c.1767T>G0.938
gyrB7012c.1773G>C0.938
gyrB7018c.1779G>C0.931
gyrB7021c.1782G>C0.931
gyrB7033c.1794G>C0.935
gyrB7051p.Glu604Asp0.944
gyrB7060c.1821T>C0.951
gyrB7066c.1827G>C0.950
gyrB7075c.1836T>G0.938
gyrB7078c.1839A>G0.938
gyrB7081c.1842T>C0.938
gyrB7084c.1845A>G0.939
gyrB7093c.1854T>C0.946
gyrB7099c.1860G>A0.946
gyrB7108c.1869G>A1.000
gyrB7114c.1875C>A1.000
gyrB7124p.Ser629Thr1.000
gyrB7129c.1890T>G1.000
gyrB7132c.1893T>G1.000
gyrB7136c.1897T>C1.000
gyrB7141c.1902T>C1.000
gyrB7144c.1905A>G1.000
gyrB7147c.1908G>C1.000
gyrB7165c.1926C>G1.000
gyrB7178c.1939T>C1.000
gyrB7216c.1977G>C0.926
gyrB7225c.1986T>C0.923
gyrB7237c.1998C>T0.917
gyrA7355c.54T>C1.000
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T1.000
gyrA7394c.93T>C1.000
gyrA7427c.126G>C1.000
gyrA7442c.141G>C1.000
gyrA7451c.150C>G1.000
gyrA7457c.156T>C1.000
gyrA7472c.171T>C1.000
gyrA7475c.174A>C1.000
gyrA7480p.Phe60Tyr1.000
gyrA7484c.183T>C1.000
gyrA7487c.186C>G1.000
gyrA7490c.189C>T1.000
gyrA7517c.216G>A1.000
gyrA7523c.222C>G1.000
gyrA7532c.231T>C1.000
gyrA7538c.237G>A1.000
gyrA7541c.240C>G1.000
gyrA7571c.270G>C1.000
gyrA7585p.Ser95Thr1.000
gyrA7595c.294C>G1.000
gyrA7607c.306C>G1.000
gyrA7622c.321C>T1.000
gyrA7626c.325C>T1.000
gyrA7631c.330G>C1.000
gyrA7637c.336C>G1.000
gyrA7646c.345C>T1.000
gyrA7649c.348C>T1.000
gyrA7652c.351C>T1.000
gyrA7658c.357A>G1.000
gyrA7664c.363T>C1.000
gyrA7670c.369A>G1.000
gyrA7676c.375G>C1.000
gyrA7683c.382A>C1.000
gyrA7694c.393A>G1.000
gyrA7697c.396C>G1.000
gyrA7710c.409T>C1.000
gyrA7715c.414G>C1.000
gyrA7728c.427A>C1.000
gyrA7731p.Glu144Gln1.000
gyrA7760c.459C>T1.000
gyrA7763c.462T>C1.000
gyrA7799c.498A>G1.000
gyrA7835c.534A>G1.000
gyrA7838c.537C>G1.000
gyrA7859c.558A>C1.000
gyrA7865c.564T>C1.000
gyrA7883c.582G>C1.000
gyrA7884p.Arg195Gly0.944
gyrA7892c.591G>C1.000
gyrA7898p.Asp199Glu1.000
gyrA7919p.Glu206Asp0.957
gyrA7923p.His208Tyr0.957
gyrA7928p.Asp209Glu0.950
gyrA7942p.Glu214Ala0.947
gyrA7955c.654G>C0.933
gyrA7958c.657C>G0.933
gyrA7963p.Gly221Glu0.933
gyrA7970c.669T>G0.933
gyrA7976c.675C>A0.929
gyrA7979c.678G>C0.929
gyrA8036c.735A>G1.000
gyrA8039c.738T>C1.000
gyrA8054c.753T>C1.000
gyrA8057c.756A>G1.000
gyrA8069c.768T>C1.000
gyrA8078c.777A>G1.000
gyrA8090c.789C>G1.000
gyrA8099c.798T>C1.000
gyrA8111c.810G>C0.963
gyrA8156c.855T>C0.969
gyrA8168c.867A>G0.970
gyrA8174c.873C>G0.971
gyrA8177c.876A>C0.968
gyrA8198c.897T>C0.971
gyrA8207c.906T>C0.971
gyrA8219c.918T>C0.947
gyrA8225c.924T>C0.943
gyrA8234c.933T>G0.943
gyrA8235c.934T>C0.943
gyrA8253p.Ile318Leu0.951
gyrA8264c.963T>C0.976
gyrA8267c.966G>C0.976
gyrA8270c.969G>C0.976
gyrA8283p.Ile328Leu0.974
gyrA8288c.987T>C0.974
gyrA8294c.993T>C0.974
gyrA8324c.1023T>C0.974
gyrA8339c.1038A>G0.975
gyrA8342c.1041G>C0.975
gyrA8351c.1050C>T0.975
gyrA8366c.1065G>C1.000
gyrA8375c.1074G>C0.929
gyrA8391p.Tyr364His0.919
gyrA8399c.1098T>C0.923
gyrA8420c.1119T>C0.921
gyrA8423c.1122G>C0.921
gyrA8442c.1141C>T0.905
gyrA8453c.1152A>C0.921
gyrA8462c.1161A>G0.919
gyrA8471c.1170T>C0.917
gyrA8480c.1179C>T0.912
gyrA8486c.1185T>C0.912
gyrA8489c.1188A>G0.912
gyrA8498c.1197C>T0.914
gyrA8504c.1203G>C0.917
gyrA8516c.1215T>C0.897
gyrA8519c.1218A>C1.000
gyrA8537c.1236G>A1.000
gyrA8546c.1245T>C0.963
gyrA8552c.1251C>G0.933
gyrA8556p.Ala419Gln0.933
gyrA8561c.1260A>C0.933
gyrA8562c.1261C>T0.933
gyrA8603c.1302A>G0.906
gyrA8619c.1318T>C0.897
gyrA8624c.1323G>C0.900
gyrA8627c.1326C>G0.900
gyrA8636c.1335A>C0.906
gyrA8642c.1341A>G0.919
gyrA8645c.1344C>G0.919
gyrA8672c.1371A>G0.923
gyrA8693c.1392T>C0.951
gyrA8699c.1398A>G0.951
gyrA8711c.1410A>C0.923
gyrA8714c.1413A>G0.923
gyrA8717c.1416C>G1.000
gyrA8720c.1419G>A1.000
gyrA8726c.1425G>A1.000
gyrA8729c.1428T>C1.000
gyrA8732c.1431G>C1.000
gyrA8735c.1434C>T1.000
gyrA8747c.1446A>G1.000
gyrA8756c.1455A>G1.000
gyrA8762c.1461G>C1.000
gyrA8765p.Asp488Glu1.000
gyrA8767p.Arg489Lys1.000
gyrA8779p.Asp493Ala1.000
gyrA8786c.1485T>C1.000
gyrA8796p.Ile499Val1.000
gyrA8801c.1500G>C1.000
gyrA8810c.1509A>C1.000
gyrA8829c.1528T>C1.000
gyrA8852c.1551T>C1.000
gyrA8858c.1557T>C1.000
gyrA8867c.1566A>G1.000
gyrA8870c.1569G>C1.000
gyrA8873c.1572A>C1.000
gyrA8897c.1596T>C1.000
gyrA8903c.1602T>C1.000
gyrA8915c.1614A>G1.000
gyrA8918c.1617C>G0.630
gyrA8939c.1638T>C1.000
gyrA8942c.1641G>C1.000
gyrA8945c.1644G>C1.000
gyrA8946c.1645T>C1.000
gyrA8951c.1650G>A1.000
gyrA8966c.1665C>G0.962
gyrA8967p.Ala556Arg0.893
gyrA8987c.1686C>G0.960
gyrA8990c.1689C>G0.962
gyrA8996c.1695T>C0.966
gyrA8998p.Leu566Trp0.967
gyrA9023c.1722A>C0.889
gyrA9029c.1728T>C0.957
gyrA9032c.1731T>C0.957
gyrA9035c.1734G>C0.957
gyrA9050p.Asp583Glu0.958
gyrA9051c.1750T>C0.955
gyrA9062c.1761C>G0.933
gyrA9065c.1764C>T0.933
gyrA9068c.1767G>C0.933
gyrA9071c.1770G>C0.933
gyrA9074c.1773G>C0.933
gyrA9080c.1779G>T0.957
gyrA9099c.1798T>C0.955
gyrA9104c.1803C>G0.960
gyrA9119c.1818A>G1.000
gyrA9122c.1821C>G1.000
gyrA9134c.1833C>G1.000
gyrA9143c.1842T>C1.000
gyrA9147p.Gly616Ser1.000
gyrA9152c.1851C>T1.000
gyrA9153p.Thr618Glu1.000
gyrA9164c.1863G>C1.000
gyrA9182c.1881T>C1.000
gyrA9191c.1890G>C1.000
gyrA9200c.1899A>G1.000
gyrA9204p.Ser635Thr1.000
gyrA9227c.1926C>G1.000
gyrA9230c.1929T>C1.000
gyrA9233c.1932C>T1.000
gyrA9242c.1941A>C1.000
gyrA9252p.Val651Ile1.000
gyrA9275c.1974G>A1.000
gyrA9278c.1977G>C1.000
gyrA9281c.1980C>G1.000
gyrA9284c.1983T>C1.000
gyrA9291c.1990C>T1.000
gyrA9296c.1995T>C1.000
gyrA9304p.Gly668Glu1.000
gyrA9311c.2010C>T1.000
gyrA9323c.2022C>G0.938
gyrA9335c.2034G>C0.939
gyrA9345c.2044A>C0.943
gyrA9374c.2073G>C0.968
gyrA9377c.2076A>G0.968
gyrA9383c.2082T>C0.967
gyrA9386c.2085T>C0.967
gyrA9395c.2094G>C0.971
gyrA9413c.2112G>C0.963
gyrA9419c.2118T>C0.900
gyrA9443c.2142G>C0.929
gyrA9449c.2148C>G0.929
gyrA9452c.2151G>C0.929
gyrA9455c.2154T>C0.929
gyrA9458c.2157A>G0.929
gyrA9467c.2166T>C1.000
gyrA9518c.2217A>G1.000
gyrA9521c.2220C>T1.000
gyrA9527c.2226A>G1.000
gyrA9542c.2241T>C1.000
gyrA9545c.2244A>G1.000
gyrA9548c.2247T>C1.000
gyrA9557c.2256G>C1.000
gyrA9560c.2259C>G1.000
gyrA9566c.2265C>T1.000
gyrA9575c.2274G>C1.000
gyrA9578c.2277C>T1.000
gyrA9585c.2284T>C1.000
gyrA9590c.2289T>G1.000
gyrA9593c.2292G>T1.000
gyrA9597c.2296T>C1.000
gyrA9605c.2304C>G1.000
gyrA9611p.Asp770Glu1.000
gyrA9626c.2325T>C1.000
gyrA9629c.2328C>G1.000
gyrA9630p.Val777Ile1.000
gyrA9635c.2334T>C1.000
gyrA9644c.2343T>C1.000
gyrA9647c.2346C>T1.000
gyrA9650c.2349G>C1.000
gyrA9665c.2364A>G1.000
gyrA9666p.Arg789Gly1.000
gyrA9674c.2373T>C1.000
gyrA9677c.2376C>T1.000
gyrA9701c.2400T>C1.000
gyrA9704c.2403T>C1.000
gyrA9708c.2407T>C1.000
gyrA9722c.2421C>T1.000
gyrA9734c.2433A>G1.000
gyrA9738c.2437T>C1.000
gyrA9749c.2448G>C1.000
rpoB759573c.-234T>C1.000
rpoB759606c.-201T>C1.000
rpoB759644c.-163T>A1.000
rpoB759647c.-160T>C1.000
rpoB759817p.Ser4Phe1.000
rpoB759914c.108T>C0.933
rpoB759929c.123A>G1.000
rpoB759932c.126T>C1.000
rpoB760059p.Tyr85Asp1.000
rpoB760070c.264T>G1.000
rpoB760088c.282C>G0.944
rpoB760091c.285G>C0.944
rpoB760091r.285g>gc0.944
rpoB760101c.295T>C1.000
rpoB760106c.300G>T1.000
rpoB760112c.306T>C1.000
rpoB760118c.312T>C1.000
rpoB760121c.315T>C1.000
rpoB760130p.Asp108Glu1.000
rpoB760139c.333A>G1.000
rpoB760142c.336C>G1.000
rpoB760181c.375T>C1.000
rpoB760184c.378A>G1.000
rpoB760196c.390C>G1.000
rpoB760223c.417T>C1.000
rpoB760235c.429T>C1.000
rpoB760253c.447T>C1.000
rpoB760283c.477G>C0.939
rpoB760307c.501T>C0.944
rpoB760328c.522G>C0.909
rpoB760331c.525G>C0.939
rpoB760337c.531C>G0.939
rpoB760340c.534G>C0.941
rpoB760361c.555T>C0.917
rpoB760376p.Asp190Glu0.917
rpoB760406c.600G>C0.950
rpoB760418c.612G>C1.000
rpoB760424c.618C>G1.000
rpoB760430c.624T>C1.000
rpoB760475c.669A>G1.000
rpoB760481c.675G>C1.000
rpoB760484c.678A>G1.000
rpoB760514c.708C>T1.000
rpoB760522p.Ser239Asn1.000
rpoB760532c.726T>C1.000
rpoB760533p.Val243Thr1.000
rpoB760547c.741G>C1.000
rpoB760563p.Arg253Met1.000
rpoB760591p.Val262Ala1.000
rpoB760611c.805T>C1.000
rpoB760634c.828T>C0.944
rpoB760646c.840C>G0.939
rpoB760655c.849A>G0.943
rpoB760661c.855A>C0.938
rpoB760670c.864G>C0.929
rpoB760674c.868T>C0.944
rpoB760679c.873A>G0.943
rpoB760683c.877T>C0.941
rpoB760718c.912C>G0.944
rpoB760721c.915C>G0.944
rpoB760724c.918T>C0.947
rpoB760730c.924T>C0.950
rpoB760751c.945G>C0.949
rpoB760757c.951T>C0.929
rpoB760759p.Val318Ala0.929
rpoB760763c.957C>T0.929
rpoB760769c.963C>G0.920
rpoB760775c.969G>C1.000
rpoB760776c.970T>A1.000
rpoB760793c.987A>G1.000
rpoB760805c.999G>C1.000
rpoB760817c.1011A>G1.000
rpoB760820c.1014T>C1.000
rpoB760826c.1020C>G1.000
rpoB760830c.1024T>C1.000
rpoB760845p.Thr347Pro1.000
rpoB760859c.1053T>C1.000
rpoB760862c.1056G>C1.000
rpoB760869p.Val355Ile1.000
rpoB760886c.1080A>G1.000
rpoB760919c.1113C>G1.000
rpoB760925c.1119T>C1.000
rpoB760928c.1122G>C1.000
rpoB760934c.1128C>T1.000
rpoB760946c.1140A>G1.000
rpoB760970c.1164G>C1.000
rpoB760982c.1176G>C1.000
rpoB760985c.1179G>C1.000
rpoB760991c.1185G>C1.000
rpoB761015c.1209G>C1.000
rpoB761021c.1215G>C1.000
rpoB761027c.1221A>G1.000
rpoB761036c.1230G>C1.000
rpoB761037c.1231T>C1.000
rpoB761051c.1245G>T1.000
rpoB761054c.1248G>C1.000
rpoB761057c.1251G>C1.000
rpoB761060c.1254C>G1.000
rpoB761063c.1257C>G1.000
rpoB761097c.1291A>T1.000
rpoB761102c.1296A>G1.000
rpoB761133c.1327T>C1.000
rpoB761150c.1344A>C1.000
rpoB761165c.1359G>C0.926
rpoB761168c.1362C>G0.927
rpoB761171c.1365C>T1.000
rpoB761180c.1374A>C1.000
rpoB761183c.1377T>G1.000
rpoB761189c.1383T>G1.000
rpoB761222c.1416G>C1.000
rpoB761249c.1443A>G1.000
rpoB761255c.1449T>G1.000
rpoB761261c.1455G>T1.000
rpoB761327c.1521A>G1.000
rpoB761360c.1554T>C1.000
rpoB761362p.Ser519Thr1.000
rpoB761373p.Val523His1.000
rpoB761414c.1608A>G1.000
rpoB761423c.1617T>C1.000
rpoB761434543DAD>543DGN1.000
rpoB761441p.Asp545Glu1.000
rpoB761444c.1638T>C1.000
rpoB761447c.1641C>G1.000
rpoB761452p.Val549Ala1.000
rpoB761457p.Pro551Ala1.000
rpoB761462c.1656C>G1.000
rpoB761492c.1686G>C1.000
rpoB761510c.1704T>C1.000
rpoB761531c.1725C>G1.000
rpoB761537c.1731C>G1.000
rpoB761570c.1764T>C1.000
rpoB761573c.1767C>G0.978
rpoB761579c.1773G>C1.000
rpoB761606c.1800C>G1.000
rpoB761612c.1806G>C1.000
rpoB761615c.1809A>C1.000
rpoB761636c.1830G>T1.000
rpoB761645c.1839C>G1.000
rpoB761648c.1842T>C1.000
rpoB761657c.1851C>G1.000
rpoB761675c.1869G>C1.000
rpoB761690c.1884G>C0.882
rpoB761722639EES>639EKS0.964
rpoB761732c.1926C>G1.000
rpoB761735c.1929C>G1.000
rpoB761747c.1941G>C1.000
rpoB761750c.1944G>C1.000
rpoB761765c.1959T>C1.000
rpoB761772p.His656Ala1.000
rpoB761778p.Asn658Asp1.000
rpoB761791p.Arg662His1.000
rpoB761813c.2007T>C1.000
rpoB761815p.Ala670Glu1.000
rpoB761834c.2028T>C0.969
rpoB761847p.Cys681Ser0.968
rpoB761852c.2046C>G0.968
rpoB761858c.2052G>C0.967
rpoB761864c.2058G>C0.967
rpoB761873c.2067A>G0.969
rpoB761885c.2079T>C0.969
rpoB761891c.2085G>C0.968
rpoB761906c.2100C>G0.947
rpoB761909c.2103T>C0.938
rpoB761912c.2106T>C0.938
rpoB761915p.Asp703Glu0.938
rpoB761916p.Asp704Asn0.938
rpoB761931c.2125C>T1.000
rpoB761948c.2142G>C1.000
rpoB761954c.2148C>G1.000
rpoB761999c.2193G>C1.000
rpoB762008c.2202C>G1.000
rpoB762014c.2208C>T1.000
rpoB762017c.2211A>G1.000
rpoB762027c.2221C>T1.000
rpoB762032c.2226C>G1.000
rpoB762035c.2229G>C1.000
rpoB762053c.2247T>C1.000
rpoB762062c.2256T>C1.000
rpoB762065c.2259T>C1.000
rpoB762083c.2277T>C1.000
rpoB762086c.2280G>C1.000
rpoB762101c.2295C>G1.000
rpoB762114p.Ile770Val1.000
rpoB762131c.2325C>G1.000
rpoB762140c.2334G>C1.000
rpoB762143c.2337T>C1.000
rpoB762149c.2343G>C1.000
rpoB762167c.2361T>C1.000
rpoB762176c.2370T>C1.000
rpoB762185c.2379G>C1.000
rpoB762218c.2412T>G1.000
rpoB762254c.2448T>C1.000
rpoB762266c.2460T>C1.000
rpoB762284c.2478G>C1.000
rpoB762293c.2487T>C1.000
rpoB762317c.2511A>G1.000
rpoB762329c.2523G>C1.000
rpoB762338c.2532T>C1.000
rpoB762347c.2541T>C1.000
rpoB762362p.Glu852Asp1.000
rpoB762369c.2563T>C1.000
rpoB762374c.2568G>C1.000
rpoB762380c.2574T>G1.000
rpoB762395c.2589G>C1.000
rpoB762398c.2592T>C1.000
rpoB762401c.2595G>C1.000
rpoB762404c.2598T>C1.000
rpoB762410c.2604T>C1.000
rpoB762416c.2610A>G1.000
rpoB762443c.2637G>C0.968
rpoB762470c.2664G>C0.968
rpoB762489p.Val895Gln0.964
rpoB762509c.2703T>G0.893
rpoB762510p.Ala902Pro0.893
rpoB762521c.2715C>G0.938
rpoB762533c.2727T>C0.929
rpoB762536c.2730T>C0.929
rpoB762537c.2731T>C0.929
rpoB762551c.2745C>T0.933
rpoB762581c.2775T>C1.000
rpoB762582c.2776T>C1.000
rpoB762710c.2904G>A1.000
rpoB762729p.Gln975Lys0.933
rpoB762734c.2928G>A0.933
rpoB762736p.Ala977Glu0.933
rpoB762744p.Gln980Ala0.933
rpoB762750p.Leu982Met0.938
rpoB762753c.2947T>C0.938
rpoB762782c.2976T>C0.955
rpoB762785p.Asp993Glu0.944
rpoB762788c.2982G>C0.941
rpoB762789p.Leu995Met0.941
rpoB762794c.2988C>G0.952
rpoB762799p.Ala998Gly0.952
rpoB762812c.3006C>G0.950
rpoB762813p.Met1003Val0.950
rpoB762818c.3012C>G0.950
rpoB762827c.3021G>C0.947
rpoB762830c.3024C>G0.941
rpoB762831c.3025A>T0.941
rpoB762836c.3030C>G0.941
rpoB762857c.3051C>G0.972
rpoB762860c.3054G>C0.972
rpoB762863c.3057T>C0.972
rpoB762929c.3123G>C1.000
rpoB762989c.3183G>C1.000
rpoB762995c.3189G>T1.000
rpoB763028c.3222T>C1.000
rpoB763031c.3225T>G1.000
rpoB763034c.3228C>G1.000
rpoB763040c.3234C>G1.000
rpoB763070c.3264T>C1.000
rpoB763076c.3270C>G1.000
rpoB763085c.3279C>G1.000
rpoB763115c.3309T>C1.000
rpoB763136c.3330C>T1.000
rpoB763148c.3342G>C1.000
rpoB763158c.3352C>T1.000
rpoB763166c.3360A>G1.000
rpoB763169c.3363A>G1.000
rpoB763202c.3396A>C1.000
rpoB763205c.3399G>C1.000
rpoB763206c.3400A>T1.000
rpoB763214c.3408T>C1.000
rpoB763226c.3420A>G1.000
rpoB763238c.3432T>C1.000
rpoB763268c.3462C>G1.000
rpoB763283c.3477T>C1.000
rpoB763284c.3478C>T1.000
rpoC763402c.33C>G1.000
rpoC763411c.42T>G1.000
rpoC763414c.45T>C1.000
rpoC763441c.72C>G1.000
rpoC763444c.75T>C1.000
rpoC763456c.87A>G1.000
rpoC763468c.99G>C1.000
rpoC763486c.117T>C1.000
rpoC763528c.159G>A1.000
rpoC763546c.177A>G1.000
rpoC763570c.201G>C1.000
rpoC763594c.225C>T1.000
rpoC763633c.264T>C1.000
rpoC763636c.267T>C1.000
rpoC763642c.273G>C1.000
rpoC763658c.289C>T1.000
rpoC763675c.306C>G1.000
rpoC763696c.327T>C0.972
rpoC763702c.333C>G1.000
rpoC763708c.339G>A1.000
rpoC763709c.340C>T1.000
rpoC763714c.345G>C1.000
rpoC763717c.348T>C1.000
rpoC763723c.354G>C1.000
rpoC763732c.363C>G0.971
rpoC763735c.366G>C1.000
rpoC763744c.375G>C1.000
rpoC763765c.396T>C1.000
rpoC763768c.399C>G1.000
rpoC763780c.411C>G1.000
rpoC763783c.414G>C1.000
rpoC763801c.432C>G1.000
rpoC763807c.438T>C1.000
rpoC763819c.450G>C1.000
rpoC763831c.462A>G1.000
rpoC763835p.Ala156Met1.000
rpoC763858c.489A>G1.000
rpoC763872p.Gly168Ala1.000
rpoC763876p.Glu169Asp1.000
rpoC763879c.510A>G1.000
rpoC763885c.516C>G1.000
rpoC763888c.519G>C1.000
rpoC763891c.522G>C1.000
rpoC763894c.525A>G1.000
rpoC763945c.576T>C1.000
rpoC763960c.591T>C1.000
rpoC763967p.Gly200Ser1.000
rpoC763978c.609C>G1.000
rpoC763996c.627T>C1.000
rpoC764005c.636G>C1.000
rpoC764011c.642T>C1.000
rpoC764024c.655T>C1.000
rpoC764040p.Ser224Asn0.966
rpoC764044c.675T>C0.967
rpoC764059c.690G>C0.971
rpoC764083c.714A>G0.972
rpoC764098c.729A>G0.974
rpoC764101c.732C>G0.974
rpoC764110c.741C>T0.971
rpoC764131c.762T>C0.970
rpoC764161c.792G>C0.971
rpoC764188c.819A>G1.000
rpoC764195p.Ser276Gln1.000
rpoC764203c.834G>T1.000
rpoC764206c.837T>C1.000
rpoC764257c.888G>C1.000
rpoC764266c.897T>C1.000
rpoC764269c.900G>C1.000
rpoC764282c.913T>A1.000
rpoC764365c.996C>T0.966
rpoC764380c.1011G>C0.952
rpoC764381c.1012T>A0.952
rpoC764387c.1018T>C0.952
rpoC764405c.1036A>C1.000
rpoC764431c.1062G>C1.000
rpoC764434c.1065A>G1.000
rpoC764446c.1077T>C1.000
rpoC764449c.1080G>C1.000
rpoC764452c.1083T>C1.000
rpoC764458c.1089G>C1.000
rpoC764461c.1092A>G1.000
rpoC764497c.1128A>G1.000
rpoC764503c.1134G>C1.000
rpoC764521c.1152T>C1.000
rpoC764536c.1167G>C1.000
rpoC764539c.1170C>G1.000
rpoC764560c.1191T>C1.000
rpoC764566c.1197C>G1.000
rpoC764573c.1204C>T1.000
rpoC764576c.1207T>A1.000
rpoC764581c.1212T>C1.000
rpoC764626c.1257C>T1.000
rpoC764632c.1263T>C1.000
rpoC764650c.1281G>T1.000
rpoC764695c.1326T>C1.000
rpoC764716c.1347G>C1.000
rpoC764752c.1383G>C1.000
rpoC764764c.1395T>C1.000
rpoC764791c.1422C>G1.000
rpoC764809c.1440C>T1.000
rpoC764812c.1443C>G1.000
rpoC764815c.1446A>G1.000
rpoC764824c.1455T>C1.000
rpoC764830c.1461C>G1.000
rpoC764858c.1489T>C1.000
rpoC764872c.1503A>G1.000
rpoC764878c.1509C>G1.000
rpoC764893c.1524T>C1.000
rpoC764911c.1542A>G1.000
rpoC764923c.1554A>G1.000
rpoC764932c.1563C>A1.000
rpoC764968c.1599T>C1.000
rpoC764995c.1626C>G1.000
rpoC765007c.1638T>G1.000
rpoC765019c.1650A>G1.000
rpoC765034c.1665T>C1.000
rpoC765040c.1671T>C1.000
rpoC765041c.1672T>C1.000
rpoC765047c.1678T>C1.000
rpoC765052c.1683C>G1.000
rpoC765073c.1704G>C1.000
rpoC765076c.1707A>G1.000
rpoC765079c.1710T>G1.000
rpoC765082c.1713G>C1.000
rpoC765085c.1716T>C1.000
rpoC765089c.1720T>C1.000
rpoC765103c.1734G>A1.000
rpoC765287c.1918C>T1.000
rpoC765292c.1923G>T1.000
rpoC765298c.1929G>T1.000
rpoC765300p.Val644Ala1.000
rpoC765319c.1950A>G1.000
rpoC765325c.1956C>T1.000
rpoC765326p.His653Ala1.000
rpoC765330p.Ser654Asn1.000
rpoC765349c.1980T>C1.000
rpoC765352c.1983G>C1.000
rpoC765383p.Met672Leu1.000
rpoC765404p.Leu679Val1.000
rpoC765409c.2040T>C1.000
rpoC765412c.2043T>C1.000
rpoC765421c.2052C>G1.000
rpoC765451c.2082C>G0.895
rpoC765452p.Ala695Ser0.895
rpoC765478c.2109T>C1.000
rpoC765493c.2124G>C1.000
rpoC765499c.2130C>G1.000
rpoC765508c.2139C>G1.000
rpoC765541c.2172C>G1.000
rpoC765553c.2184C>T1.000
rpoC765556c.2187G>C1.000
rpoC765559c.2190G>C1.000
rpoC765573p.Asp735Gly1.000
rpoC765577c.2208G>C1.000
rpoC765578c.2209C>T1.000
rpoC765583c.2214G>T1.000
rpoC765613p.His748Gln0.938
rpoC765625c.2256C>G0.931
rpoC765628c.2259G>C0.931
rpoC765631p.Asp754Glu0.933
rpoC765658c.2289C>T0.947
rpoC765700c.2331T>C0.940
rpoC765734c.2365T>C0.939
rpoC765739c.2370G>C0.940
rpoC765751c.2382C>G0.935
rpoC765753p.Asp795Ala0.977
rpoC765772c.2403C>G1.000
rpoC765784c.2415C>G1.000
rpoC765796c.2427C>T1.000
rpoC765811c.2442T>C0.953
rpoC765814c.2445A>G0.952
rpoC765826c.2457T>C0.956
rpoC765835c.2466C>T0.952
rpoC765883c.2514C>G0.955
rpoC765886c.2517C>G0.953
rpoC765892c.2523T>C0.956
rpoC765928c.2559C>G0.964
rpoC765967c.2598C>T1.000
rpoC765979c.2610C>G1.000
rpoC765982c.2613C>T1.000
rpoC765985c.2616C>T1.000
rpoC765994c.2625A>T1.000
rpoC766009c.2640G>C1.000
rpoC766010c.2641T>A1.000
rpoC766015c.2646G>A1.000
rpoC766021c.2652G>C1.000
rpoC766043p.Gln892Glu1.000
rpoC766054c.2685C>G1.000
rpoC766069c.2700G>A1.000
rpoC766082p.Ala905Gln0.975
rpoC766096c.2727G>C1.000
rpoC766105c.2736C>T1.000
rpoC766129c.2760C>G1.000
rpoC766135c.2766G>A1.000
rpoC766141c.2772C>T1.000
rpoC766142c.2773C>T1.000
rpoC766258c.2889T>C1.000
rpoC766270c.2901G>C1.000
rpoC766273c.2904T>C1.000
rpoC766274p.Ala969Thr1.000
rpoC766279c.2910C>G1.000
rpoC766280p.Ser971Gly1.000
rpoC766299p.Thr977Ile1.000
rpoC766309c.2940G>C1.000
rpoC766312c.2943T>G1.000
rpoC766315c.2946C>G1.000
rpoC766327c.2958C>G1.000
rpoC766345c.2976T>C1.000
rpoC766348c.2979A>G1.000
rpoC766363c.2994G>C1.000
rpoC766381c.3012C>T1.000
rpoC766384c.3015A>G1.000
rpoC766390c.3021C>T1.000
rpoC766408c.3039C>T1.000
rpoC766426c.3057C>T1.000
rpoC766444c.3075C>G1.000
rpoC766447c.3078T>C0.974
rpoC766483c.3114G>C1.000
rpoC766484p.Val1039Ile1.000
rpoC766492c.3123T>C1.000
rpoC766495c.3126C>T1.000
rpoC766528c.3159T>G1.000
rpoC766543c.3174C>T1.000
rpoC766573c.3204T>C1.000
rpoC766583p.Gly1072Ser1.000
rpoC766591c.3222A>G1.000
rpoC766594c.3225G>C1.000
rpoC766597c.3228C>G1.000
rpoC766607p.Ile1080Leu1.000
rpoC766630c.3261G>C1.000
rpoC766645c.3276A>G1.000
rpoC766651c.3282T>C1.000
rpoC766657c.3288A>G1.000
rpoC766672c.3303T>C1.000
rpoC766738c.3369G>T1.000
rpoC766750c.3381C>G1.000
rpoC766765c.3396A>C1.000
rpoC766769c.3400C>T1.000
rpoC766774c.3405T>C1.000
rpoC766801c.3432C>G1.000
rpoC766804c.3435A>G1.000
rpoC766861c.3492G>C1.000
rpoC766864c.3495G>C1.000
rpoC766894c.3525T>C1.000
rpoC766895c.3526T>C1.000
rpoC766900c.3531T>C1.000
rpoC766933c.3564A>G0.960
rpoC766945c.3576A>G0.962
rpoC766963c.3594T>C0.968
rpoC766972c.3603G>C0.971
rpoC766978c.3609C>G0.973
rpoC766996c.3627C>T0.977
rpoC767009c.3640T>A0.973
rpoC767014c.3645G>C0.973
rpoC767033c.3664T>A0.975
rpoC767059c.3690T>G1.000
rpoC767062c.3693C>A1.000
rpoC767074c.3705T>C0.982
rpoC767098c.3729T>C0.982
rpoC767119c.3750A>G0.982
rpoC767134c.3765C>G0.981
rpoC767158c.3789T>G0.979
rpoC767167c.3798C>G0.980
rpoC767180p.Ala1271Gln0.977
rpoC767191c.3822C>G0.975
rpoC767206c.3837C>G0.969
rpoC767209c.3840T>C0.969
rpoC767212c.3843G>C0.968
rpoC767221c.3852C>G1.000
rpoC767230c.3861G>C1.000
rpoC767233c.3864T>C1.000
rpoC767263c.3894T>C1.000
rpoC767264p.Ala1299Gln1.000
rpoC767275c.3906T>C1.000
rpoC767278c.3909T>C1.000
rpoC767281c.3912C>G1.000
rpoC767284c.3915C>G1.000
rpsL781348c.-212C>G1.000
rpsL781353c.-207T>C1.000
rpsL781373c.-187G>C1.000
rpsL781571c.12C>T1.000
rpsL781608p.Ser17Gly1.000
rpsL781631c.72G>C1.000
rpsL781649c.90T>C1.000
rpsL781655c.96T>C1.000
rpsL781682c.123T>C1.000
rpsL781715c.156T>C1.000
rpsL781728c.169T>C1.000
rpsL781736c.177T>C1.000
rpsL781751c.192G>C1.000
rpsL781754c.195G>C1.000
rpsL781760c.201T>C1.000
rpsL781793c.234G>C1.000
rpsL781832c.273T>C1.000
rpsL781841c.282C>G1.000
rpsL781859c.300T>C1.000
rpsL781868c.309T>C1.000
rpsL781871c.312G>C1.000
rpsL781892c.333A>G1.000
rpsL781898c.339A>T1.000
rpsL781916c.357T>C1.000
rpsL781929p.Gly124Ser1.000
rplC800796c.-13A>T1.000
rplC800797c.-12TTGG>T1.000
rplC800814c.6A>G0.974
rplC800817c.9A>T0.974
rplC800844c.36T>C0.974
rplC800865c.57A>G0.975
rplC800867p.Ser20Asn0.974
rplC800874c.66A>G0.976
rplC800877c.69A>C0.976
rplC800880c.72A>G0.976
rplC800889c.81C>G0.979
rplC800907c.99C>G0.974
rplC800916c.108A>G0.980
rplC800937c.129A>G0.971
rplC800939p.Arg44Gln0.971
rplC800946c.138T>C0.971
rplC800949c.141T>C0.971
rplC800955c.147C>G1.000
rplC800967c.159C>G1.000
rplC800970c.162T>C1.000
rplC800982c.174C>T1.000
rplC800985c.177A>G1.000
rplC800994c.186C>G1.000
rplC801004p.Leu66Val1.000
rplC801009c.201A>C1.000
rplC801012c.204T>C1.000
rplC801019p.Thr71Ala1.000
rplC801024c.216C>G1.000
rplC801027c.219C>G1.000
rplC801031p.Val75Ile1.000
rplC801039c.231A>G1.000
rplC801045c.237A>G1.000
rplC801047p.Tyr80Phe1.000
rplC801054c.246G>C1.000
rplC801070p.Asp88Asn1.000
rplC801073p.Ser89Pro1.000
rplC801078c.270T>C1.000
rplC801081c.273C>G1.000
rplC801085p.Thr93Ala1.000
rplC801090c.282G>A1.000
rplC801099c.291T>C1.000
rplC801102c.294G>C1.000
rplC801105c.297A>G1.000
rplC801109c.301T>C1.000
rplC801114c.306C>G1.000
rplC801127p.Ala107Thr1.000
rplC801132c.324T>C1.000
rplC801147c.339T>C1.000
rplC801150c.342G>C1.000
rplC801153c.345G>C1.000
rplC801156c.348T>A1.000
rplC801171c.363A>G1.000
rplC801174c.366T>C1.000
rplC801183c.375C>A1.000
rplC801222c.414T>C1.000
rplC801228c.420T>C1.000
rplC801246c.438C>G1.000
rplC801249c.441T>G1.000
rplC801255c.447C>T1.000
rplC801267c.459A>C1.000
rplC801270c.462T>C1.000
rplC801276c.468G>C1.000
rplC801279c.471G>C1.000
rplC801282c.474G>C1.000
rplC801301c.493C>A1.000
rplC801312c.504G>C1.000
rplC801324c.516T>C1.000
rplC801336c.528C>G1.000
rplC801339c.531T>C1.000
rplC801341p.Leu178Gln1.000
rplC801348c.540T>G1.000
rplC801357c.549T>C1.000
rplC801367p.Ala187Thr1.000
rplC801396c.588T>C1.000
rplC801402c.594T>C1.000
rplC801405c.597T>C1.000
rplC801417c.609T>C1.000
rplC801423c.615G>C1.000
rplC801438c.630T>C1.000
rplC801442p.Ile212Val1.000
rplC801461653G>A1.000
embR1416295c.1053A>G0.900
embR1416310c.1038C>G0.909
embR1416316c.1032G>C1.000
rrs1471923r.78t>c1.000
rrs1471934r.89a>g0.982
rrs1471969r.124t>c0.984
rrs1471970r.125g>a0.984
rrs1472028r.183a>t0.984
rrs1472030r.185g>a0.984
rrs1472031r.186g>a0.984
rrs1472034r.189t>c0.984
rrs1472044r.199g>c0.986
rrs1472053r.208agc>a0.986
rrs1472061r.216a>t0.985
rrs1472075r.230a>g0.985
rrs1472969r.1124a>g1.000
rrs1472970r.1125c>g1.000
rrs1472977r.1132g>c1.000
rrs1472978r.1133t>c1.000
rrs1473104r.1259c>t1.000
rrs1473105r.1260g>a1.000
rrs1473120r.1275c>ct0.898
rrs1473123r.1278a>t1.000
rrs1473145r.1300c>t1.000
rrs1473166r.1321g>a1.000
rrs1473288r.1443c>ctt0.809
rrs1473290r.1445c>t0.975
rrs1473382r.1537t>g1.000
rrl1473399c.-259A>AG1.000
rrl1473401c.-257G>A1.000
rrl1473417c.-241C>T1.000
rrl1473419c.-239T>C1.000
rrl1473420c.-238A>G1.000
rrl1473421c.-237G>A1.000
rrl1473436c.-222T>C1.000
rrl1473437c.-221T>C1.000
rrl1473569c.-89A>T0.977
rrl1473571c.-87C>T0.976
rrl1473668r.11c>t0.929
rrl1473756r.99g>a0.940
rrl1473758r.101g>t0.939
rrl1473806r.149c>t0.964
rrl1473813r.156c>t0.982
rrl1473839r.182g>t0.983
rrl1473877r.220g>a0.964
rrl1473898r.241c>t0.966
rrl1473899r.242a>c0.983
rrl1473937r.280c>t0.982
rrl1473944r.287g>a0.981
rrl1473945r.288t>c0.980
rrl1473981r.324g>t0.976
rrl1473995r.338g>t0.981
rrl1474001r.344c>t0.982
rrl1474009r.352a>g0.982
rrl1474012r.355c>t0.982
rrl1474025r.368t>g0.983
rrl1474051r.394t>c0.980
rrl1474054r.397t>c0.980
rrl1474056r.399t>c0.980
rrl1474103r.446a>t0.973
rrl1474104r.447g>a0.971
rrl1474111r.454t>c0.971
rrl1474112r.455t>a0.973
rrl1474140r.483c>t1.000
rrl1474151r.494c>t1.000
rrl1474181r.524c>t1.000
rrl1474249r.592g>t1.000
rrl1474290r.633ttttcctctccggagg>t0.979
rrl1474306r.649a>c0.970
rrl1474308r.651g>t0.970
rrl1474310r.653t>g0.971
rrl1474356r.699t>c0.969
rrl1474362r.705a>g0.968
rrl1474376r.719t>c0.968
rrl1474427r.770a>c0.944
rrl1474429r.772g>c0.944
rrl1474432r.775c>g0.944
rrl1474639r.982g>a1.000
rrl1474794r.1137c>t0.984
rrl1474812r.1155g>a0.982
rrl1474823r.1166c>t0.984
rrl1474831r.1174a>g0.983
rrl1474904r.1247g>a1.000
rrl1474956r.1299c>t1.000
rrl1474958r.1301a>at0.978
rrl1474959r.1302c>t0.977
rrl1474962r.1305tg>t0.977
rrl1474964r.1307t>tac0.977
rrl1474970r.1313g>a1.000
rrl1474991r.1334t>c1.000
rrl1475006r.1349a>t1.000
rrl1475061r.1404c>t1.000
rrl1475088r.1431a>t1.000
rrl1475199r.1542g>a0.979
rrl1475206r.1549c>t0.979
rrl1475209r.1552g>c0.981
rrl1475213r.1556c>t0.981
rrl1475249r.1592t>c0.983
rrl1475252r.1595c>t0.983
rrl1475266r.1609t>c1.000
rrl1475271r.1614a>c1.000
rrl1475273r.1616t>a1.000
rrl1475275r.1618c>t1.000
rrl1475276r.1619t>c1.000
rrl1475291r.1634a>c1.000
rrl1475313r.1656g>a1.000
rrl1475315r.1658a>t0.985
rrl1475333r.1676t>c1.000
rrl1475355r.1698c>t1.000
rrl1475369r.1712g>c0.985
rrl1475419r.1762c>t0.983
rrl1475483r.1826c>t0.983
rrl1475505r.1848g>a1.000
rrl1475526r.1869c>a1.000
rrl1475599r.1942a>g1.000
rrl1475608r.1951t>c1.000
rrl1475638r.1981c>t0.983
rrl1475642r.1985t>c1.000
rrl1475657r.2000a>g1.000
rrl1475659r.2002g>t0.982
rrl1475763r.2106c>t1.000
rrl1475881r.2224t>c1.000
rrl1475988r.2331a>g1.000
rrl1476025r.2368g>t1.000
rrl1476030r.2373a>g1.000
rrl1476032r.2375c>a1.000
rrl1476033r.2376t>c1.000
rrl1476034r.2377c>a1.000
rrl1476045r.2388g>t1.000
rrl1476047r.2390g>t1.000
rrl1476049r.2392c>t1.000
rrl1476086r.2429g>a1.000
rrl1476089r.2432t>c1.000
rrl1476095r.2438c>g1.000
rrl1476106r.2449a>t1.000
rrl1476115r.2458t>c1.000
rrl1476117r.2460g>c1.000
rrl1476224r.2567a>g1.000
rrl1476281r.2624t>c1.000
rrl1476384r.2727g>a1.000
rrl1476583r.2926g>a1.000
rrl1476584r.2927c>t1.000
rrl1476597r.2940g>a1.000
rrl1476608r.2951c>g1.000
rrl1476628r.2971t>a1.000
rrl1476689r.3032a>t1.000
rrl1476690r.3033c>t0.970
rrl1476693r.3036g>a1.000
rrl1476695r.3038t>a1.000
rrl1476716r.3059a>c1.000
rrl1476723r.3066t>a1.000
rrl1476725r.3068c>t1.000
rrl1476726r.3069a>g1.000
rrl1476732r.3075t>c1.000
rrl1476755r.3098g>a1.000
rrl1476759r.3102t>c1.000
rrl1476770r.3113t>c1.000
rrl1476771r.3114g>a1.000
fabG11673481c.42A>C1.000
fabG11673487c.48T>C1.000
fabG11673490c.51A>C1.000
fabG11673499c.60T>G1.000
fabG11673517c.78G>C1.000
fabG11673523c.84G>T1.000
fabG11673535c.96A>C1.000
fabG11673547c.108T>C1.000
fabG11673574c.135C>G1.000
fabG11673580c.141T>C1.000
fabG11673589c.150A>G1.000
fabG11673595c.156A>C1.000
fabG11673596p.Lys53Asp1.000
fabG11673607c.168T>C1.000
fabG11673610c.171C>T1.000
fabG11673616c.177A>G1.000
fabG11673619c.180T>C1.000
fabG11673633p.Ser65Asn1.000
fabG11673646c.207T>C1.000
fabG11673658c.219G>A1.000
fabG11673660p.Ala74Glu1.000
fabG11673664c.225A>G1.000
fabG11673667c.228A>G1.000
fabG11673679c.240T>G1.000
fabG11673709c.270C>T1.000
fabG11673710p.Leu91Ile1.000
fabG11673716p.Ala93Lys1.000
fabG11673730c.291C>G0.955
fabG11673733p.Met98Ile1.000
fabG11673748c.309A>G1.000
fabG11673749p.Lys104Arg1.000
fabG11673755p.Glu106Thr1.000
fabG11673758p.Lys107Glu1.000
fabG11673778c.339C>G1.000
fabG11673890p.Ala151Ser1.000
fabG11673901c.462A>G1.000
fabG11673905p.Ser156Ala1.000
fabG11673916c.477A>C1.000
fabG11673917p.Val160Leu1.000
fabG11673922c.483T>C1.000
fabG11673925c.486C>G1.000
fabG11673941p.Ala168Ser1.000
fabG11673949c.510G>A1.000
fabG11673955c.516G>C1.000
fabG11674003c.564C>G1.000
fabG11674006p.Asp189Glu1.000
fabG11674018c.579G>C1.000
fabG11674024c.585T>C1.000
fabG11674079p.Pro214Ala1.000
fabG11674084c.645C>G1.000
fabG11674098p.Val220Ala1.000
fabG11674114c.675T>C1.000
fabG11674123c.684T>C1.000
fabG11674126c.687G>C1.000
fabG11674129c.690C>T1.000
fabG11674132c.693T>C1.000
fabG11674136p.Ser233Ala1.000
fabG11674141c.702T>C1.000
fabG11674147c.708C>G1.000
fabG11674153c.714G>C1.000
fabG11674165c.726C>T1.000
fabG11674171c.732T>C1.000
inhA1674199c.-3C>G1.000
inhA1674205p.Thr2Ala1.000
inhA1674216c.15G>C0.951
inhA1674231c.30T>C0.961
inhA1674237c.36T>C0.961
inhA1674239p.Ser13Thr0.961
inhA1674243c.42A>G0.961
inhA1674279c.78A>C0.920
inhA1674280p.Arg27Lys0.920
inhA1674285c.84A>G0.920
inhA1674296p.Gln32Arg0.920
inhA1674307c.106C>T0.923
inhA1674315c.114C>G0.938
inhA1674321c.120G>C0.968
inhA1674342c.141T>C0.969
inhA1674352p.Thr51Val1.000
inhA1674368p.Ala56Glu1.000
inhA1674379c.178C>T1.000
inhA1674382p.Leu61Ile1.000
inhA1674387c.186A>G1.000
inhA1674399c.198A>G1.000
inhA1674415p.Ala72Asn1.000
inhA1674419p.Ser73Thr1.000
inhA1674421c.220T>C1.000
inhA1674427p.Gly76Gln1.000
inhA1674440p.Glu80Ala1.000
inhA1674443p.Ala81Glu1.000
inhA1674450c.249G>C1.000
inhA1674452p.Ala84Glu1.000
inhA1674480c.279T>C1.000
inhA1674486c.285T>C1.000
inhA1674489c.288G>C1.000
inhA1674507c.306G>C1.000
inhA1674537c.336C>G1.000
inhA1674542p.Ala114Glu1.000
inhA1674549c.348G>C1.000
inhA1674555c.354G>A1.000
inhA1674561c.360C>T1.000
inhA1674582c.381T>C1.000
inhA1674585c.384T>C1.000
inhA1674589p.Met130Leu1.000
inhA1674624c.423A>C1.000
inhA1674627c.426T>G1.000
inhA1674630c.429C>G1.000
inhA1674636c.435C>G1.000
inhA1674654c.453G>C1.000
inhA1674693c.492C>G1.000
inhA1674703c.502T>C0.952
inhA1674718c.517A>C0.963
inhA1674741c.540C>G0.933
inhA1674742p.Lys181Pro0.933
inhA1674745p.Tyr182His0.933
inhA1674750c.549T>C0.933
inhA1674756c.555T>C0.944
inhA1674771c.570C>G0.882
inhA1674774c.573A>G0.875
inhA1674780c.579T>G0.882
inhA1674786c.585G>C0.882
inhA1674848p.Gln216Arg0.800
inhA1674855c.654C>G0.875
inhA1674876c.675C>G0.909
inhA1674879c.678T>C0.913
inhA1674903c.702T>C0.952
inhA1674904p.Ala235Pro0.952
inhA1674909c.708G>C0.957
inhA1674915c.714C>G0.962
inhA1674942c.741T>C1.000
inhA1674957c.756G>C1.000
inhA1674963c.762G>C1.000
inhA1674966c.765T>C1.000
inhA1674967p.Asp256Thr1.000
inhA1674993c.792G>C1.000
inhA1674994p.His265Ser1.000
inhA1675008c.807C>G1.000
rpsA1833489c.-53T>A1.000
rpsA1833512c.-30AC>A1.000
rpsA1833518c.-24C>A1.000
rpsA1833541c.-1T>C1.000
rpsA1833554p.Thr5Ala1.000
rpsA1833568c.27G>C1.000
rpsA1833589c.48A>T1.000
rpsA1833595c.54T>C1.000
rpsA1833619c.78A>C1.000
rpsA1833661c.120A>G1.000
rpsA1833667c.126C>G1.000
rpsA1833724c.183C>G1.000
rpsA1833727c.186G>C1.000
rpsA1833742c.201A>G1.000
rpsA1833745c.204G>C1.000
rpsA1833787c.246C>G1.000
rpsA1833790c.249T>A1.000
rpsA1833793c.252C>T1.000
rpsA1833799c.258C>G1.000
rpsA1833811c.270G>C1.000
rpsA1833838c.297G>C1.000
rpsA1833841c.300C>G1.000
rpsA1833847c.306C>G1.000
rpsA1833856c.315A>G1.000
rpsA1833862c.321G>T1.000
rpsA1833874c.333T>C1.000
rpsA1833928c.387G>C1.000
rpsA1833940c.399C>G1.000
rpsA1833970c.429G>C1.000
rpsA1833979c.438T>C1.000
rpsA1834000c.459G>C1.000
rpsA1834015c.474G>C1.000
rpsA1834021c.480C>T1.000
rpsA1834097c.556T>A1.000
rpsA1834102c.561T>C1.000
rpsA1834150c.609G>C1.000
rpsA1834153c.612T>C1.000
rpsA1834154p.Asn205Gln1.000
rpsA1834157c.616T>C1.000
rpsA1834162c.621A>G1.000
rpsA1834165c.624A>G1.000
rpsA1834169p.Thr210Ala1.000
rpsA1834177c.636A>C1.000
rpsA1834186c.645C>G1.000
rpsA1834189c.648G>C1.000
rpsA1834195c.654G>C1.000
rpsA1834222c.681T>C1.000
rpsA1834225c.684C>G1.000
rpsA1834231c.690T>C1.000
rpsA1834240c.699T>C1.000
rpsA1834249c.708T>C1.000
rpsA1834261c.720A>C1.000
rpsA1834264c.723G>C1.000
rpsA1834297c.756C>G1.000
rpsA1834303c.762T>G1.000
rpsA1834306c.765T>C1.000
rpsA1834348c.807T>C1.000
rpsA1834366c.825A>G1.000
rpsA1834375c.834G>A1.000
rpsA1834396c.855G>C1.000
rpsA1834411c.870T>C1.000
rpsA1834417c.876G>C1.000
rpsA1834423c.882G>C1.000
rpsA1834435c.894G>C1.000
rpsA1834451c.910T>C1.000
rpsA1834465c.924T>C0.973
rpsA1834468c.927A>G1.000
rpsA1834474c.933C>G1.000
rpsA1834489c.948T>C1.000
rpsA1834498c.957C>T0.973
rpsA1834513c.972C>G1.000
rpsA1834528c.987T>G1.000
rpsA1834546c.1005T>C0.980
rpsA1834555c.1014T>C0.958
rpsA1834558c.1017C>G0.980
rpsA1834606c.1065C>G0.949
rpsA1834609c.1068T>C0.927
rpsA1834622c.1081T>A0.914
rpsA1834633c.1092A>G0.929
rpsA1834639c.1098T>C0.911
rpsA1834666c.1125G>C0.951
rpsA1834669c.1128G>C0.952
rpsA1834688c.1147A>T0.956
rpsA1834726c.1185C>A0.981
rpsA1834732c.1191T>C0.980
rpsA1834733p.Ala398Pro0.981
rpsA1834753c.1212T>C0.984
rpsA1834765c.1224A>G1.000
rpsA1834780c.1239A>G1.000
rpsA1834786c.1245A>G1.000
rpsA1834789c.1248T>C1.000
rpsA1834792c.1251G>C1.000
rpsA1834852c.1311C>G1.000
tlyA1917951c.12T>C1.000
tlyA1917972c.33A>G1.000
tlyA1917981c.42G>C0.938
tlyA1917990c.51G>C0.933
tlyA1917993c.54A>G0.933
tlyA1917996c.57A>G0.933
tlyA1917999c.60T>C0.933
tlyA1918002c.63A>G0.938
tlyA1918015c.76T>C0.957
tlyA1918036p.Arg33Ser0.955
tlyA1918048p.Leu37Met0.952
tlyA1918191c.252G>C1.000
tlyA1918197c.258T>C1.000
tlyA1918206c.267G>C1.000
tlyA1918212c.273A>G1.000
tlyA1918218c.279C>G1.000
tlyA1918233c.294A>G1.000
tlyA1918236c.297A>G1.000
tlyA1918377c.438T>G1.000
tlyA1918379p.Arg147Pro1.000
tlyA1918382p.Val148Ala1.000
tlyA1918392c.453A>G1.000
tlyA1918398c.459C>G1.000
tlyA1918417c.478T>C1.000
tlyA1918420p.Ala161Cys1.000
tlyA1918425c.486C>G1.000
tlyA1918434c.495C>G1.000
tlyA1918442p.Val168Ala1.000
tlyA1918446c.507A>C1.000
tlyA1918459p.Asp174His1.000
tlyA1918464c.525C>G1.000
tlyA1918476c.537A>C1.000
tlyA1918477p.Leu180Met1.000
tlyA1918506c.567A>G1.000
tlyA1918509c.570T>C1.000
tlyA1918518c.579C>G1.000
tlyA1918603p.Ser222Pro1.000
tlyA1918610p.Gly224Asp1.000
tlyA1918616p.Lys226Thr0.909
katG2155742p.Gly124Gln0.966
katG2155747p.Ala122Gly0.935
katG2155782c.330G>C1.000
katG2155785c.327A>G1.000
katG2155788c.324G>A1.000
katG2155796p.Ala106Ser1.000
katG2155806c.306A>G1.000
katG2155847p.Pro89Asp1.000
pncA2288816c.426C>G1.000
pncA2288820p.Gln141Arg1.000
pncA2288822c.420G>C1.000
pncA2288828c.414A>G1.000
pncA2288834c.408A>G1.000
pncA2288843c.399A>G1.000
pncA2288846c.396A>G1.000
pncA2288855c.387A>G1.000
pncA2288864c.378A>G1.000
pncA2288870c.372G>C1.000
pncA2288903c.339G>C1.000
pncA2288909p.Glu111Asp1.000
pncA2288918c.324T>G1.000
pncA2288921c.321T>C1.000
pncA2289074c.168G>A1.000
pncA2289194c.48A>G1.000
pncA2289206c.36G>A1.000
pncA2289212c.30C>T1.000
kasA2518121p.Gln3Lys1.000
kasA2518132c.18C>T1.000
kasA2518138c.24T>C1.000
kasA2518146p.Phe11Tyr1.000
kasA2518162c.48G>A1.000
kasA2518174c.60A>G1.000
kasA2518190p.Ser26Ala1.000
kasA2518199p.Ile29Val1.000
kasA2518222c.108G>A1.000
kasA2518223c.109T>C1.000
kasA2518234c.120G>A1.000
kasA2518248p.Ala45Val1.000
kasA2518261p.Glu49Asp1.000
kasA2518263p.Phe50Tyr1.000
kasA2518265p.Val51Ile1.000
kasA2518459c.345T>C1.000
kasA2518462c.348A>C1.000
kasA2518468c.354A>T1.000
kasA2518475c.361A>C1.000
kasA2518480c.366T>C1.000
kasA2518483c.369C>G1.000
kasA2518504c.390T>C1.000
kasA2518506p.Ala131Glu1.000
kasA2518519c.405G>C1.000
kasA2518528c.414C>G1.000
kasA2518540c.426T>G1.000
kasA2518561c.447T>C1.000
kasA2518567c.453G>C1.000
kasA2518570c.456G>C1.000
kasA2518574p.Ile154Val1.000
kasA2518588c.474T>C1.000
kasA2518591c.477G>C1.000
kasA2518609p.Met165Ile1.000
kasA2518621c.507G>A1.000
kasA2518642c.528A>G1.000
kasA2518663c.549T>C1.000
kasA2518672c.558G>C1.000
kasA2518687c.573C>T1.000
kasA2518696c.582C>G1.000
kasA2518702c.588C>T1.000
kasA2518711c.597A>G0.967
kasA2518714c.600A>C0.963
kasA2518732c.618C>G0.909
kasA2518741c.627G>C0.886
kasA2518747c.633C>G0.917
kasA2518768c.654C>G0.906
kasA2518783c.669T>C0.925
kasA2518792c.678C>G0.929
kasA2518795c.681C>G0.929
kasA2518816c.702C>A0.936
kasA2518822c.708C>G0.930
kasA2518825c.711T>C0.933
kasA2518855c.741C>G0.932
kasA2518864c.750G>C0.933
kasA2518879c.765A>G0.955
kasA2518885c.771T>C0.976
kasA2518888c.774C>T0.976
kasA2518898c.784T>C0.977
kasA2518906c.792A>G0.977
kasA2518910p.Leu266Met0.976
kasA2518921c.807T>C0.975
kasA2518927c.813C>G0.964
kasA2518930c.816G>C0.964
kasA2518936c.822C>G0.960
kasA2518939c.825T>C0.960
kasA2518942c.828T>C0.960
kasA2518951c.837G>C0.958
kasA2518954c.840C>G0.958
kasA2518963c.849T>C0.952
kasA2519053c.939G>C1.000
kasA2519062c.948T>G1.000
kasA2519068c.954C>T1.000
kasA2519072p.Ala320Thr1.000
kasA2519077c.963G>C1.000
kasA2519095c.981C>G0.975
kasA2519098c.984C>G0.975
kasA2519104c.990T>A0.975
kasA2519108p.Asp332Gln0.975
kasA2519111p.Gln333Glu0.975
kasA2519116c.1002C>G0.975
kasA2519125c.1011C>T0.962
kasA2519137c.1023T>C0.962
kasA2519146c.1032C>A0.962
kasA2519167c.1053T>C0.957
kasA2519173c.1059C>G0.958
kasA2519176c.1062G>A0.957
kasA2519197c.1083G>C0.956
kasA2519215c.1101C>T0.947
kasA2519221c.1107G>C0.939
kasA2519225c.1111C>T0.939
kasA2519323c.1209G>C1.000
kasA2519329c.1215C>T1.000
kasA2519338c.1224T>C1.000
kasA2519344c.1230G>A1.000
kasA2519347c.1233T>G1.000
kasA2519359c.1245T>C1.000
ahpC2726288c.96C>T0.818
ahpC2726303c.111T>C0.846
ahpC2726312c.120T>C0.815
ahpC2726315p.Asp41Glu0.815
ahpC2726318p.Glu42Asp0.815
ahpC2726322p.Pro44Ala0.815
ahpC2726336c.144G>C0.828
ahpC2726348c.156T>C0.871
ahpC2726354c.162G>C0.889
ahpC2726357c.165A>G0.962
ahpC2726366c.174G>C1.000
ahpC2726372c.180G>C1.000
ahpC2726378c.186T>C1.000
ahpC2726390c.198G>C1.000
ahpC2726391p.Ala67Thr1.000
ahpC2726397p.Ser69Gly1.000
ahpC2726408c.216T>C1.000
ahpC2726528c.336C>G0.783
ahpC2726546c.354C>G0.750
ahpC2726551p.Gln120Leu0.789
ahpC2726556p.Ala122Thr0.810
ahpC2726564c.372C>T0.852
ahpC2726570c.378C>T0.857
ahpC2726579c.387T>C0.839
ahpC2726591c.399C>G0.964
ahpC2726593p.Val134Ala0.964
ahpC2726600c.408T>C0.968
ahpC2726612c.420C>G0.974
ahpC2726638p.Ala149Val0.979
ahpC2726645c.453C>G0.978
ahpC2726657c.465A>C0.981
ahpC2726669p.Asp159Glu0.979
ahpC2726672c.480G>A0.978
ahpC2726675c.483A>G0.978
ahpC2726681c.489A>G0.978
ahpC2726687c.495C>G0.977
ahpC2726693c.501C>G0.977
ahpC2726696c.504C>G0.976
ahpC2726717c.525A>G0.972
ahpC2726735c.543C>T0.968
folC2746555c.1044C>A1.000
folC2746561c.1038G>T1.000
folC2746564c.1035T>G1.000
folC2746569p.Ser344Arg1.000
folC2746576c.1023G>T1.000
folC2746584c.1015C>A1.000
folC2746594c.1005A>G1.000
folC2746728c.871A>G1.000
folC2746734p.Ile289Val1.000
folC2746741c.858G>A1.000
folC2746744c.855A>C1.000
folC2746753c.846G>C1.000
folC2746756c.843G>C1.000
folC2746765c.834T>C0.909
folC2747023c.576G>C1.000
folC2747032c.567T>G1.000
folC2747040p.Ile187Val1.000
folC2747059c.540A>G1.000
folC2747065c.534G>C1.000
folC2747086c.513T>G1.000
folC2747089c.510C>G1.000
folC2747098c.501G>C1.000
folC2747101c.498C>G1.000
folC2747107c.492C>G1.000
folC2747110c.489A>G1.000
folC2747113c.486G>C1.000
folC2747116c.483C>G1.000
folC2747149c.450G>A0.973
folC2747221c.378C>T0.909
folC2747224c.375C>G0.909
folC2747234p.Ala122Asp0.909
folC2747236c.363C>G0.909
folC2747243p.Gln119Arg0.909
folC2747245c.354C>G0.913
folC2747264p.Gly112Ala0.919
folC2747275c.324A>G0.923
folC2747281c.318T>C0.946
folC2747289p.Pro104Ala0.963
folC2747290c.309T>G0.963
folC2747293c.306C>T0.964
folC2747302c.297T>C0.970
folC2747314c.285T>G0.925
folC2747317c.282G>C0.925
folC2747355p.Val82Ile0.919
folC2747359c.240G>C0.919
folC2747362c.237C>G0.925
folC2747394p.Ile69Val0.848
folC2747395c.204A>G0.844
folC2747401c.198C>G0.833
folC2747407c.192A>G0.828
folC2747412p.Ser63Ala0.815
folC2747416c.183T>C0.846
folC2747419c.180G>C0.846
folC2747430c.169G>A0.865
folC2747439p.Met54Leu0.861
folC2747442c.157A>G0.861
folC2747443c.156C>T0.865
folC2747464c.135C>G0.892
folC2747467p.Asp44Glu0.889
folC2747475p.Arg42Lys0.917
folC2747491c.108T>C0.889
folC2747497c.102G>C0.857
folC2747500c.99T>C0.857
folC2747503c.96A>G0.857
folC2747506c.93C>T0.857
folC2747509c.90A>G0.857
folC2747523p.Ser26Ala0.875
folC2747524c.75C>G0.833
folC2747539c.60A>G0.875
ribD2987580p.Ser248Ala1.000
thyX3067199c.747T>C0.926
thyX3067205c.741C>G0.939
thyX3067210c.736A>G0.892
thyX3067220c.726C>G0.927
thyX3067223c.723C>G0.930
thyX3067244c.702G>C0.940
thyX3067249p.Thr233Ala0.939
thyX3067252p.Val232Ile0.939
thyX3067277c.669G>C0.922
thyX3067280c.666C>G0.920
thyX3067284p.Ala221Asp0.913
thyX3067286c.660G>C0.955
thyX3067289c.657G>C0.955
thyX3067293p.Gln218Arg0.956
thyX3067304c.642T>C0.957
thyX3067316c.630T>C0.951
thyX3067325c.621T>C0.952
thyX3067355c.591T>G0.949
thyX3067367c.579C>G0.944
thyX3067376c.570C>G0.943
thyX3067391c.555C>G0.935
thyX3067394c.552C>G0.935
thyX3067412c.534G>C1.000
thyX3067439c.507T>C1.000
thyX3067445c.501G>C1.000
thyX3067451c.495C>T1.000
thyX3067457c.489G>C1.000
thyX3067465p.Ile161Val1.000
thyX3067466c.480C>G1.000
thyX3067470p.Asn159Ser1.000
thyX3067493c.453T>C1.000
thyX3067500p.Lys149Arg1.000
thyX3067515p.Ser144Thr1.000
thyX3067526c.420G>C1.000
thyX3067531p.Ala139Ser1.000
thyX3067545p.Glu134Ala1.000
thyX3067549p.Thr133Ala1.000
thyX3067556p.His130Gln1.000
thyX3067560p.Arg129Gln1.000
thyX3067565p.Asp127Glu1.000
thyX3067570p.Ala126Pro1.000
thyX3067571c.375G>A1.000
thyX3067577p.Glu123Asp1.000
thyX3067582p.Met122Leu1.000
thyX3067586c.360G>C1.000
thyX3067601c.345C>G1.000
thyX3067604c.342C>G1.000
thyX3067610p.Lys112Asn1.000
thyX3067613c.333C>T1.000
thyX3067619c.327T>G1.000
thyX3067640c.306C>G1.000
thyX3067643c.303G>A1.000
thyX3067652c.294A>G0.977
thyX3067661c.285G>C0.976
thyX3067682c.264C>G0.970
thyX3067685c.261T>C0.970
thyX3067688c.258C>G0.971
thyX3067694c.252C>G0.971
thyX3067718c.228G>C0.938
thyX3067721c.225A>G0.929
thyX3067724c.222C>T0.929
thyX3067727c.219T>G0.929
thyX3067739c.207A>G0.938
thyX3067742c.204T>G0.929
thyX3067762p.Arg62Lys0.944
thyX3067765p.Leu61Ile0.944
thyX3067781c.165G>C1.000
thyX3067787c.159C>T1.000
thyX3067793c.153A>G1.000
thyX3067799c.147C>T1.000
thyX3067802c.144G>C1.000
thyX3067814c.132A>G1.000
thyX3067826c.120G>C1.000
thyX3067850c.96T>G1.000
thyX3067869p.Thr26Ser1.000
thyX3067874c.72G>C1.000
thyX3067883c.63G>C1.000
thyX3067886c.60T>G0.944
thyX3067889c.57G>C1.000
thyX3067894c.52A>G1.000
thyX3067935p.Thr4Ile1.000
thyA3073692c.780T>G1.000
thyA3073695c.777A>G1.000
thyA3073698c.774T>C1.000
thyA3073704c.768C>G1.000
thyA3073710c.762A>G1.000
thyA3073727p.Lys249His1.000
thyA3073731c.741A>C1.000
thyA3073736p.Ile246Val1.000
thyA3073740p.Glu244Asp1.000
thyA3073743c.729A>G1.000
thyA3073752p.Glu240Asp1.000
thyA3073761c.711T>C1.000
thyA3073815c.657C>T1.000
thyA3073824c.648T>G0.971
thyA3073827c.645T>C0.972
thyA3073839c.633A>G0.974
thyA3073863c.609A>G0.979
thyA3073874p.Ile200Val0.977
thyA3073878c.594C>T0.977
thyA3073892c.580A>G0.979
thyA3073893c.579G>T0.978
thyA3073925c.547A>G0.977
thyA3073929c.543A>G0.978
thyA3073953c.519A>G0.976
thyA3073977c.495T>C0.970
thyA3073989c.483A>G0.968
thyA3074001c.471G>C0.958
thyA3074004c.468A>G0.960
thyA3074010c.462G>C0.957
thyA3074031c.441A>G0.967
thyA3074037c.435G>C0.967
thyA3074057p.Glu139Pro0.963
thyA3074061c.411T>C0.963
thyA3074076c.396G>C0.966
thyA3074082c.390C>G0.963
thyA3074097c.375G>C0.962
thyA3074100c.372A>G0.962
thyA3074106c.366A>G0.966
thyA3074117c.355G>A1.000
thyA3074120c.352A>G1.000
thyA3074130c.342C>G1.000
thyA3074157c.315G>C0.933
thyA3074160c.312T>C0.933
thyA3074165p.Ala103Thr0.929
thyA3074172c.300C>G0.929
thyA3074175c.297T>C0.929
thyA3074181c.291T>C0.929
thyA3074184c.288T>C1.000
thyA3074187c.285A>G0.929
thyA3074199c.273C>T0.938
thyA3074205p.Glu89Asp0.941
thyA3074214c.258A>G0.842
thyA3074217c.255A>G0.842
thyA3074235c.237G>A0.850
thyA3074244c.228T>G0.842
thyA3074252p.Glu74Arg0.800
thyA3074263p.Gly70Asp0.727
thyA3074267p.Ile69Val0.727
thyA3074268c.204A>G0.727
thyA3074274c.198A>G0.786
thyA3074286c.186A>G0.833
thyA3074297c.175G>A0.769
thyA3074301c.171G>A0.833
thyA3074305p.Ala56Val0.833
thyA3074307c.165T>C0.833
thyA3074318p.Phe52Leu0.833
thyA3074322c.150G>C0.833
thyA3074325c.147T>C0.857
thyA3074334c.138A>G0.917
thyA3074339p.Leu45Ile0.917
thyA3074349c.123A>G0.923
thyA3074360c.112A>G1.000
thyA3074361c.111A>G1.000
thyA3074372p.Met34Leu1.000
thyA3074394c.78G>C1.000
thyA3074397c.75T>C1.000
ald3087557c.738A>C1.000
ald3087563p.Lys248Asn1.000
ald3087566c.747A>G1.000
ald3087567p.Val250Ile1.000
ald3087578c.759A>G1.000
ald3087590p.His257Gln1.000
ald3087596c.777A>G1.000
ald3087597p.Pro260Ser1.000
ald3087602c.783T>C1.000
ald3087608c.789A>G1.000
ald3087617c.798T>C0.941
ald3087620c.801A>C0.941
ald3087621p.Ala268Ser0.941
ald3087641c.822T>C0.952
ald3087647c.828A>G0.941
ald3087649p.Gly277Asp0.941
ald3087653c.834A>C0.938
ald3087656c.837A>G0.938
ald3087665c.846C>G0.941
ald3087666p.Tyr283His0.941
ald3087672p.His285Asp0.947
ald3087680c.861G>C0.947
ald3087699p.Leu294Val0.920
ald3087704c.885T>C0.880
ald3087726p.Ala303Ser0.850
ald3087729p.Ser304Ala0.850
ald3087737c.918G>C0.850
fbiA3640291c.-252T>C1.000
fbiA3640301c.-242GTTAAC>G1.000
fbiA3640307c.-236C>A1.000
fbiA3640347c.-196A>G1.000
fbiA3640349c.-194A>G1.000
fbiA3640350c.-193C>T1.000
fbiA3640365c.-178C>G1.000
fbiA3640562p.Ala7Val1.000
fbiA3640569c.27A>G1.000
fbiA3640572c.30C>T1.000
fbiA3640681p.Val47Ile1.000
fbiA3640689c.147C>T1.000
fbiA3640707c.165G>A1.000
fbiA3640713c.171T>C1.000
fbiA3640722c.180G>C1.000
fbiA3640726c.184C>T1.000
fbiA3640878c.336T>C1.000
fbiA3640899c.357G>C1.000
fbiA3640900p.Gln120Asn1.000
fbiA3640914c.372C>G1.000
fbiA3640918p.Ser126Thr1.000
fbiA3640931p.Glu130Ala1.000
fbiA3640935c.393C>G1.000
fbiA3640938c.396A>G1.000
fbiA3640944c.402T>C1.000
fbiA3640956c.414G>C1.000
fbiA3641073c.531T>C1.000
fbiA3641085c.543G>C1.000
fbiA3641088c.546G>C1.000
fbiA3641097c.555T>C1.000
fbiA3641100c.558T>G1.000
fbiA3641103c.561T>C1.000
fbiA3641112c.570T>C1.000
fbiA3641274c.732G>C1.000
fbiA3641288p.Glu249Gly1.000
fbiA3641314p.Thr258Ala1.000
fbiA3641322c.780T>G1.000
fbiA3641328c.786T>G1.000
fbiA3641340p.Asp266Glu1.000
fbiA3641349c.807G>C1.000
fbiA3641351p.Ala270Glu1.000
fbiA3641355c.813T>C1.000
fbiA3641358c.816G>C1.000
fbiA3641364c.822G>C1.000
fbiA3641380p.Cys280Arg1.000
fbiA3641384p.Ala281Gly1.000
fbiA3641394c.852A>C1.000
fbiA3641400c.858C>T1.000
alr3840215c.1206A>G1.000
alr3840230c.1191A>C1.000
alr3840233c.1188T>C1.000
alr3840236c.1185T>G1.000
alr3840239c.1182C>G1.000
alr3840248c.1173G>C1.000
alr3840274p.Val383Leu1.000
alr3840275c.1146A>C1.000
alr3840287c.1134G>A1.000
alr3840293c.1128A>G1.000
alr3840296c.1125C>G1.000
alr3840302c.1119C>T1.000
alr3840310p.Arg371Asn1.000
alr3840312p.Ile370Ser1.000
alr3840328c.1093A>G1.000
alr3840329c.1092A>G1.000
alr3840344c.1077T>C1.000
alr3840353c.1068A>G1.000
alr3840357p.Leu355Pro1.000
alr3840382p.Met347Val1.000
alr3840436p.Leu329Ser1.000
alr3840442p.Glu327Gln1.000
alr3840469p.Val318Ile1.000
alr3840476c.945T>G1.000
alr3840482c.939A>G1.000
alr3840487p.Ile312Val1.000
alr3840503c.918A>G1.000
alr3840516p.Pro302Gln1.000
alr3840522p.Ile300Thr1.000
alr3840527c.894T>G1.000
alr3840533c.888C>T1.000
alr3840536c.885A>G1.000
alr3840539c.882C>T1.000
alr3840547p.Gly292Ser1.000
alr3840548c.873C>T1.000
alr3840560c.861A>T1.000
alr3840566c.855T>C1.000
alr3840575c.846C>T1.000
alr3840578c.843A>C1.000
alr3840583p.Ala280Thr1.000
alr3840593c.828G>C1.000
alr3840602c.819C>G1.000
alr3840611c.810C>G1.000
alr3840659c.762G>A1.000
alr3840665c.756C>G1.000
alr3840673p.Leu250Met1.000
alr3840682p.Thr247Ala1.000
alr3840926c.495A>G0.938
alr3840944c.477A>G0.944
alr3840947c.474C>G0.944
alr3840959c.462C>G0.905
alr3840965c.456C>G0.867
alr3840968c.453C>G0.867
alr3841041p.Asp127Gly0.962
alr3841060p.Gly121Arg0.962
alr3841100c.321T>C0.917
alr3841104p.Thr106Ser0.917
alr3841106c.315A>G0.917
alr3841109c.312G>C1.000
alr3841113p.Asp103Ala1.000
alr3841115c.306A>G1.000
alr3841127c.294T>C0.929
alr3841148c.273G>C0.909
alr3841208c.213A>G0.957
alr3841232c.189C>G0.958
alr3841240p.Leu61Val0.958
alr3841249p.His58Gly0.938
alr3841252p.Gly57Arg0.938
alr3841256p.His55Gln0.938
alr3841264p.Arg53Cys0.938
alr3841270p.Val51Leu0.938
alr3841283c.138T>C1.000
alr3841286c.135A>G1.000
alr3841289c.132A>G1.000
panD4044120c.162T>C1.000
panD4044123c.159A>G1.000
panD4044126c.156A>G1.000
panD4044138c.144A>G1.000
panD4044150c.132T>C1.000
panD4044162c.120T>C1.000
panD4044165c.117C>G1.000
panD4044188c.94A>G1.000
panD4044195c.87A>G1.000
panD4044213c.69G>C1.000
panD4044240c.42C>G1.000
panD4044246c.36G>C1.000
panD4044249c.33G>A1.000
panD4044264c.18C>G1.000
embC4240006c.144A>G1.000
embC4240010c.148C>T1.000
embC4240019p.Asn53Asp1.000
embC4240033c.171G>C1.000
embC4240036c.174A>G1.000
embC4240037c.175T>C1.000
embC4240059p.Thr66Ser1.000
embC4240065p.Ala68Gly1.000
embC4240069c.207T>C1.000
embC4240072c.210C>G1.000
embC4240078c.216A>G1.000
embC4240087c.225T>C1.000
embC4240090c.228C>T1.000
embC4240105c.243C>T1.000
embC4240123c.261C>G1.000
embC4240141c.279A>G1.000
embC4240155p.Gln98Pro1.000
embC4240160p.Thr100Pro1.000
embC4240183c.321A>G1.000
embC4240204c.342T>C1.000
embC4240210c.348C>G1.000
embC4240216c.354T>C1.000
embC4240229p.Leu123Ile1.000
embC4240232p.Gln124Val1.000
embC4240258c.396T>G1.000
embC4240267c.405T>C1.000
embC4240270c.408T>C1.000
embC4240277p.Leu139Val1.000
embC4240282c.420C>G1.000
embC4240285c.423C>G1.000
embC4240297c.435T>C1.000
embC4240306c.444C>G1.000
embC4240313p.Thr151Ala1.000
embC4240318c.456T>C1.000
embC4240330c.468A>C1.000
embC4240435c.573C>T1.000
embC4240444c.582C>G1.000
embC4240459c.597G>C1.000
embC4240462c.600G>C1.000
embC4240475p.Ala205Ser1.000
embC4240480c.618G>A1.000
embC4240489c.627A>G1.000
embC4240495c.633T>C1.000
embC4240512p.Ser217Thr1.000
embC4240514p.Val218Ile1.000
embC4240519c.657T>C1.000
embC4240543c.681G>C1.000
embC4240561c.699C>G1.000
embC4240573c.711G>C1.000
embC4240574p.Val238Leu1.000
embC4240578p.Ala239Val1.000
embC4240582c.720C>G1.000
embC4240591c.729C>G1.000
embC4240594c.732C>G1.000
embC4240600c.738G>C1.000
embC4240632p.Met257Thr1.000
embC4240642c.780G>C1.000
embC4240645c.783G>C1.000
embC4240654c.792C>T1.000
embC4240657c.795G>C1.000
embC4240671p.Thr270Ile1.000
embC4240678c.816T>G1.000
embC4240685p.Thr275Ala1.000
embC4240693c.831T>C1.000
embC4240706p.Val282Thr1.000
embC4240726c.864G>C1.000
embC4240780c.918T>C1.000
embC4240783c.921G>C0.933
embC4240789c.927T>C1.000
embC4240819c.957A>G1.000
embC4240831c.969T>G1.000
embC4240867c.1005T>G1.000
embC4240870c.1008T>C1.000
embC4240879c.1017G>C0.958
embC4240880p.Ala340Thr1.000
embC4240885c.1023T>C1.000
embC4240897c.1035C>G1.000
embC4240900c.1038A>G0.962
embC4240919c.1057C>T1.000
embC4240936c.1074A>G1.000
embC4240945c.1083T>C1.000
embC4240951c.1089C>G1.000
embC4240954p.Ile364Met1.000
embC4240957c.1095C>G1.000
embC4240966c.1104G>T1.000
embC4240979p.Thr373Gln1.000
embC4240983p.Ser374Asn1.000
embC4240990c.1128A>G1.000
embC4240996c.1134G>C1.000
embC4241017c.1155T>C1.000
embC4241023c.1161T>G1.000
embC4241026c.1164C>G1.000
embC4241035c.1173G>A1.000
embC4241050c.1188T>G1.000
embC4241104c.1242G>A1.000
embC4241107c.1245G>C1.000
embC4241137c.1275G>C1.000
embC4241140c.1278A>G1.000
embC4241141p.Ile427Val1.000
embC4241158c.1296T>C1.000
embC4241161c.1299C>G1.000
embC4241162c.1300T>C1.000
embC4241203c.1341T>C1.000
embC4241230c.1368A>G1.000
embC4241233c.1371G>C1.000
embC4241236c.1374C>G1.000
embC4241314c.1452G>C1.000
embC4241319p.Pro486Leu1.000
embC4241326c.1464T>C1.000
embC4241329c.1467T>C1.000
embC4241332c.1470T>C1.000
embC4241338c.1476C>G1.000
embC4241339p.Phe493Leu1.000
embC4241344c.1482G>C1.000
embC4241351p.Ile497Val1.000
embC4241361p.Asn500Ser1.000
embC4241363p.Leu501Met1.000
embC4241374c.1512T>C1.000
embC4241380c.1518A>C1.000
embC4241394p.Lys511Ser1.000
embC4241443c.1581C>G1.000
embC4241449c.1587C>G1.000
embC4241453p.Ile531Val1.000
embC4241473c.1611G>A1.000
embC4241479c.1617C>G1.000
embC4241480c.1618T>C1.000
embC4241488c.1626G>C1.000
embC4241500c.1638A>G1.000
embC4241501p.Ser547Thr1.000
embC4241506c.1644G>C1.000
embC4241518c.1656A>G1.000
embC4241521c.1659T>C1.000
embC4241530c.1668C>A1.000
embC4241551c.1689A>G1.000
embC4241560c.1698C>G1.000
embC4241567p.Ile569Val1.000
embC4241572c.1710C>G1.000
embC4241578c.1716G>C1.000
embC4241584c.1722T>C1.000
embC4241587c.1725C>G1.000
embC4241591p.Leu577Val1.000
embC4241611c.1749G>C1.000
embC4241614c.1752A>C1.000
embC4241617c.1755G>A1.000
embC4241623c.1761C>G1.000
embC4241626c.1764T>C1.000
embC4241644c.1782G>C1.000
embC4241648c.1786T>C1.000
embC4241657p.Ser599Pro1.000
embC4241665c.1803G>T1.000
embC4241671c.1809T>G1.000
embC4241689c.1827G>C1.000
embC4241691p.Gly610Ala1.000
embC4241695c.1833T>G1.000
embC4241704c.1842C>G1.000
embC4241707c.1845G>C1.000
embC4241713c.1851G>C1.000
embC4241719c.1857G>C1.000
embC4241725c.1863G>C1.000
embC4241727p.Phe622Tyr1.000
embC4241741p.Val627Leu1.000
embC4241746c.1884C>T1.000
embC4241747p.Val629Leu1.000
embC4241750p.Leu630Val1.000
embC4241755c.1893C>A1.000
embC4241770c.1908T>C1.000
embC4241791c.1929G>C1.000
embC4241794c.1932C>G1.000
embC4241797c.1935C>T1.000
embC4241803c.1941T>G1.000
embC4241809c.1947A>G1.000
embC4242427c.2565A>C1.000
embC4242428p.Ala856Ser1.000
embC4242434p.Val858Ile1.000
embC4242449p.Met863His1.000
embC4242460c.2598G>C1.000
embC4242517c.2655G>C1.000
embC4242519p.Thr886Ser1.000
embC4242532c.2670A>T1.000
embC4242539p.Ser893Pro1.000
embC4242552p.Arg897Gln1.000
embC4242554p.Leu898Val1.000
embC4242577c.2715A>G1.000
embC4242710p.Gln950Glu1.000
embC4242715c.2853T>C1.000
embC4242721c.2859G>C1.000
embC4242730c.2868C>T1.000
embC4242823c.2961G>C1.000
embC4242826c.2964G>C1.000
embC4242832c.2970A>C1.000
embC4242844c.2982A>G1.000
embC4242847c.2985C>G1.000
embC4242859c.2997C>T1.000
embC4242862c.3000A>G1.000
embC4242863p.Tyr1001Asn1.000
embC4242871c.3009C>G1.000
embC4242880c.3018A>G1.000
embC4242883c.3021C>G1.000
embC4242886c.3024G>A1.000
embC4242892c.3030G>C1.000
embC4242907c.3045G>A1.000
embC4242919c.3057A>G1.000
embC4242928c.3066A>G1.000
embC4242940c.3078T>C1.000
embC4242941p.His1027Asn1.000
embC4242946c.3084T>C1.000
embC4242952c.3090T>C1.000
embC4242965p.Ile1035Val1.000
embA4243433c.201A>C0.846
embA4243451c.219G>C0.846
embA4243461p.Ser77Pro0.846
embA4243467p.Ile79Val0.846
embA4243475c.243G>C0.846
embA4243485p.Asn85Asp0.846
embA4243787c.555G>T1.000
embA4243811c.579T>C1.000
embA4243817c.585T>C1.000
embA4244070p.Val280Ile0.909
embA4244084c.852C>G0.917
embA4244189c.957C>G0.923
embA4244198c.966C>G0.923
embA4244207c.975C>G0.929
embA4244216c.984C>G1.000
embA4244219c.987C>G1.000
embA4244228c.996A>G1.000
embA4244233p.Ala334Gly1.000
embA4244247p.Val339Ile1.000
embA4244254p.Arg341His1.000
embA4244257p.Phe342Trp1.000
embA4244267c.1035G>C1.000
embA4244276c.1044A>C1.000
embA4244284p.Pro351Arg1.000
embA4244298p.Ser356Ala1.000
embA4244309c.1077C>G1.000
embA4244312c.1080T>G1.000
embA4244315c.1083G>C1.000
embA4244324c.1092T>G1.000
embA4244327c.1095T>C1.000
embA4244337p.Leu369Val1.000
embA4244340p.Ser370Ala1.000
embA4244366c.1134C>G0.972
embA4244372c.1140T>G0.970
embA4244378c.1146G>A0.971
embA4244396c.1164T>C0.971
embA4244408c.1176G>C0.963
embA4244412p.Val394Met0.957
embA4244415c.1183T>C0.957
embA4244427p.Ser399Ala0.950
embA4244567c.1335C>G0.902
embA4244576c.1344G>C0.902
embA4244578p.Thr449Ser0.902
embA4244582c.1350T>C1.000
embA4244585c.1353A>T1.000
embA4244612c.1380C>G1.000
embA4244619c.1387T>C1.000
embA4244631p.Thr467Leu1.000
embA4244645c.1413T>C1.000
embA4244690c.1458G>A1.000
embA4244708c.1476C>G1.000
embA4244726c.1494C>T1.000
embA4244728p.Phe499Trp1.000
embA4244730c.1498C>T1.000
embA4244885c.1653A>G1.000
embA4244897c.1665T>C0.972
embA4244900c.1668G>C0.972
embA4244903c.1671G>C0.972
embA4244919c.1687C>T0.974
embA4244933c.1701A>G0.952
embA4244945c.1713C>G0.952
embA4244948c.1716G>C0.952
embA4244960c.1728A>C0.949
embA4244980p.Val583Ala0.769
embA4244982c.1750T>C0.769
embA4244987c.1755T>C0.667
embA4244991p.Val587Leu0.667
embA4245003p.Thr591Ala0.600
embA4245011c.1779C>T0.600
embA4245020c.1788T>C0.600
embA4245023c.1791A>G0.600
embA4245026c.1794T>C0.600
embA4245028p.Ser599Asn0.600
embA4245032c.1800A>C0.636
embA4245038c.1806C>T0.853
embA4245056c.1824C>G0.875
embA4245077c.1845G>C0.927
embA4245083c.1851A>C0.921
embA4245089c.1857G>C0.850
embA4245092c.1860C>G0.919
embA4245101c.1869G>C0.930
embA4245137c.1905T>C0.925
embA4245149c.1917C>G0.917
embA4245182c.1950T>C0.943
embA4245194c.1962G>C0.941
embA4245198p.Leu656Ile0.939
embA4245206c.1974A>G0.933
embA4245207c.1975T>C0.933
embA4245215c.1983A>G0.939
embA4245222p.Tyr664Gln0.938
embA4245242c.2010C>T0.923
embA4245245c.2013C>G0.917
embA4245248c.2016G>C0.917
embA4245257c.2025A>G0.900
embA4245263c.2031A>G0.900
embA4245268p.Asn679Ser0.947
embA4245355p.Ala708Gly1.000
embA4245368c.2136T>C1.000
embA4245377c.2145T>G1.000
embA4245388p.Ala719Gly1.000
embA4245402p.Thr724Ala1.000
embA4245407c.2175G>C1.000
embA4245408p.Leu726Ile1.000
embA4245411p.Ser727Ala1.000
embA4245414p.Thr728Ser1.000
embA4245431c.2199T>C1.000
embA4245461c.2229C>G1.000
embA4245465p.Pro745Ala1.000
embA4245470c.2238T>C1.000
embA4245485c.2253A>G1.000
embA4245489p.Val753Leu1.000
embA4245501p.Ala757Thr1.000
embA4245509c.2277A>G1.000
embA4245518c.2286A>G1.000
embA4245524c.2292G>C1.000
embA4245530c.2298T>G1.000
embA4245531p.Ile767Val1.000
embA4245535p.Ser768Asn1.000
embA4245539c.2307C>G1.000
embA4245557p.Glu775Asp1.000
embA4245569p.Glu779Asp1.000
embA4245575c.2343C>G1.000
embA4245576p.Lys782Gln1.000
embA4245587c.2355G>C1.000
embA4245593c.2361C>G1.000
embA4245594p.Ser788Thr1.000
embA4245599c.2367A>G1.000
embA4245617c.2385C>G1.000
embA4245620c.2388T>C1.000
embA4245623c.2391G>C1.000
embA4245626c.2394G>C1.000
embA4245643p.Ala804Val1.000
embA4245648p.Ile806Tyr1.000
embA4245652p.Thr807Ser1.000
embA4245659c.2427C>G1.000
embA4245674c.2442A>C1.000
embA4245677c.2445G>C1.000
embA4245683c.2451C>G0.944
embA4245689c.2457C>G1.000
embA4245692c.2460G>C1.000
embA4245693p.Ile821Val1.000
embA4245701c.2469G>C1.000
embA4245716c.2484G>C1.000
embA4245725c.2493A>C1.000
embA4245726c.2494T>C1.000
embA4245737c.2505A>C1.000
embA4245740c.2508T>C1.000
embA4245764c.2532G>C1.000
embA4245771p.Asn847Ser1.000
embA4245807c.2575T>C1.000
embA4245820p.Ser863Thr0.955
embA4245830c.2598G>C0.955
embA4245845c.2613T>G1.000
embA4245848c.2616C>G1.000
embA4245860c.2628C>G1.000
embA4245885p.Asp885Thr1.000
embA4245892p.Ile887Thr1.000
embA4245905c.2673C>G1.000
embA4245926c.2694C>G1.000
embA4245927p.Thr899Ala1.000
embA4245930p.Gly900Arg1.000
embA4245983c.2751A>C0.969
embA4245989c.2757A>G0.969
embA4245992c.2760C>G0.969
embA4246010c.2778G>C0.971
embA4246013c.2781T>C0.971
embA4246041p.Asp937Asn0.973
embA4246055c.2823T>C0.970
embA4246064c.2832T>C0.969
embA4246079c.2847C>T0.944
embA4246080p.Pro950Ser0.944
embA4246088c.2856A>G0.944
embA4246097c.2865C>G0.944
embA4246109c.2877C>G1.000
embA4246115c.2883T>G1.000
embA4246164p.Leu978Met1.000
embA4246184c.2952A>G1.000
embA4246187c.2955C>G1.000
embA4246196c.2964C>G1.000
embA4246250c.3018G>C1.000
embA4246264p.His1011Arg1.000
embA4246274c.3042G>C0.958
embA4246292c.3060A>G0.952
embA4246316c.3084T>G0.957
embA4246329p.Thr1033Leu0.962
embA4246355c.3123G>C0.950
embA4246359p.Ala1043Pro0.950
embA4246364c.3132G>C0.944
embA4246367c.3135C>T0.944
embA4246373c.3141T>C0.947
embA4246376c.3144G>C0.947
embA4246413p.His1061Phe0.955
embA4246419c.3187C>T1.000
embA4246439c.3207T>G1.000
embA4246442c.3210A>G1.000
embB4246603c.90C>G1.000
embB4246621c.108T>C1.000
embB4246624c.111C>G1.000
embB4246627c.114T>C1.000
embB4246631c.118T>C1.000
embB4246639c.126G>C1.000
embB4246642c.129G>C1.000
embB4246645c.132G>C1.000
embB4246882c.369G>C1.000
embB4247317c.804G>C1.000
embB4247326c.813A>G1.000
embB4247328p.Ser272Asn1.000
embB4247338c.825C>G1.000
embB4247348p.Thr279Ala1.000
embB4247355p.Ala281Val1.000
embB4247358p.Val282Ala1.000
embB4247365c.852A>C1.000
embB4247371c.858C>G1.000
embB4247375p.Leu288Val1.000
embB4247386c.873T>C1.000
embB4247389c.876C>G1.000
embB4247395c.882C>G1.000
embB4247401c.888T>C1.000
embB4247437c.924A>G1.000
embB4247440c.927C>G1.000
embB4247464c.951C>G1.000
embB4247470c.957T>C1.000
embB4247491c.978G>C1.000
embB4247500c.987C>G1.000
embB4247512c.999T>C1.000
embB4247536c.1023C>G0.955
embB4247554c.1041T>C0.944
embB4247566c.1053C>G0.917
embB4247567c.1054C>T0.917
embB4247572c.1059A>G0.917
embB4247579p.Ala356Phe0.917
embB4247587c.1074G>A0.917
embB4247603c.1090C>T0.944
embB4247611c.1098G>C0.938
embB4247614c.1101T>C0.938
embB4247629c.1116C>G0.950
embB4247632c.1119C>G0.950
embB4247635c.1122G>A0.950
embB4247646p.Glu378Ala0.929
embB4247655p.Lys381Arg0.923
embB4247659c.1146C>G0.923
embB4247683c.1170C>G1.000
embB4247692c.1179C>G1.000
embB4247716c.1203C>G0.947
embB4247722c.1209G>C0.938
embB4247725c.1212G>C0.938
embB4247729p.Gly406Pro0.938
embB4247743c.1230C>G0.938
embB4247746c.1233C>A0.938
embB4247776c.1263G>T0.900
embB4247779c.1266C>G0.900
embB4247785c.1272G>C0.909
embB4247956c.1443G>C1.000
embB4247974c.1461C>G0.933
embB4247977c.1464C>G0.941
embB4247986c.1473C>G0.944
embB4248007c.1494C>G0.947
embB4248011p.Ser500Ala0.947
embB4248035p.Val508Ile0.933
embB4248064c.1551G>C0.923
embB4248070c.1557T>C0.941
embB4248085c.1572T>C0.947
embB4248095c.1582C>T0.957
embB4248118c.1605T>C1.000
embB4248127c.1614G>C1.000
embB4248133c.1620C>G1.000
embB4248142c.1629T>C1.000
embB4248143c.1630T>C1.000
embB4248157c.1644A>G1.000
embB4248206p.Ser565Gly1.000
embB4248220c.1707A>G1.000
embB4248241c.1728C>T0.973
embB4248265c.1752C>T0.968
embB4248266c.1753C>T0.968
embB4248277c.1764G>C0.970
embB4248298c.1785C>T0.974
embB4248304c.1791G>C0.974
embB4248316c.1803C>G0.951
embB4248319c.1806A>G0.976
embB4248343c.1830G>C0.969
embB4248346c.1833G>C0.969
embB4248350c.1837T>C0.969
embB4248355c.1842A>G0.912
embB4248358c.1845C>G0.912
embB4248361c.1848A>G0.912
embB4248362p.Ser617Ala0.912
embB4248398c.1885C>T0.938
embB4248403c.1890G>C0.938
embB4248407c.1894T>C0.938
embB4248410p.Phe633Leu0.938
embB4248416p.Leu635Met0.938
embB4248419p.Leu636Met0.938
embB4248425c.1912T>C0.938
embB4248430c.1917T>C0.968
embB4248432p.Trp640Phe0.968
embB4248460c.1947C>G0.980
embB4248472c.1959T>G0.978
embB4248504p.Asp664Gly1.000
embB4248508c.1995G>A1.000
embB4248514c.2001A>G1.000
embB4248524p.Ile671Val1.000
embB4248649c.2136T>C1.000
embB4248659p.Ala716Leu1.000
embB4248668p.Val719Ile1.000
embB4248676c.2163C>G1.000
embB4248688c.2175G>C1.000
embB4248694c.2181G>C1.000
embB4248697c.2184A>C1.000
embB4248706c.2193G>C1.000
embB4248720p.Gly736Ala0.917
embB4248725p.Ser738Asp0.917
embB4248731p.Val740Leu0.917
embB4248736c.2223G>C0.917
embB4248738p.Ala742Glu0.917
embB4248742c.2229T>C0.917
embB4248743p.Val744Ser0.846
embB4248772c.2259A>G0.926
embB4248961c.2448T>C1.000
embB4249138c.2625C>G1.000
embB4249153c.2640G>T1.000
embB4249255c.2742G>C0.923
embB4249259p.Met916Leu0.933
embB4249268p.Asp919Tyr0.941
embB4249276c.2763A>G0.950
embB4249282c.2769A>C0.950
embB4249297c.2784G>C0.963
embB4249321c.2808A>C1.000
embB4249322p.Ala937Ser1.000
embB4249325p.Lys938Asp1.000
embB4249336c.2823C>G1.000
embB4249339c.2826T>C1.000
embB4249340p.Ala943Thr1.000
embB4249345c.2832C>G1.000
embB4249348c.2835G>C1.000
embB4249351c.2838C>G1.000
embB4249369c.2856T>C1.000
embB4249381c.2868A>G1.000
embB4249417c.2904A>G1.000
embB4249420c.2907G>C1.000
embB4249423p.Asp970Glu1.000
embB4249424p.Leu971Met1.000
embB4249432c.2919A>G1.000
embB4249441c.2928A>G1.000
embB4249444c.2931T>C1.000
embB4249447c.2934G>C1.000
embB4249456c.2943G>C1.000
embB4249469p.Leu986Met1.000
embB4249483c.2970C>G1.000
embB4249486c.2973T>G1.000
embB4249487c.2974T>C1.000
embB4249498c.2985G>C1.000
embB4249521p.Ala1003Val1.000
embB4249525c.3012T>C1.000
embB4249528c.3015C>G1.000
embB4249529p.Ile1006Val1.000
embB4249532p.Ala1007Thr1.000
embB4249537c.3024A>G1.000
embB4249543c.3030G>C1.000
embB4249558c.3045A>C1.000
embB4249564c.3051C>T1.000
embB4249568p.Ser1019Thr1.000
embB4249573c.3060T>C1.000
embB4249580p.Leu1023Met1.000
embB4249594c.3081G>C1.000
embB4249600c.3087A>G1.000
embB4249609c.3096T>C1.000
embB4249615c.3102C>G1.000
embB4249624c.3111C>G1.000
embB4249640c.3127T>C1.000
ethA4326057p.Ile473Val1.000
ethA4326059p.Lys472Arg1.000
ethA4326304c.1170G>C1.000
ethA4326307c.1167G>T1.000
ethA4326310c.1164A>G1.000
ethA4326438p.Leu346Met0.800
ethA4326445c.1029C>T0.800
ethA4326459p.Ile339Val0.818
ethA4326469c.1005A>G0.900
ethA4326483p.Arg331Glu0.800
ethA4326484c.990A>G0.800
ethA4326487c.987T>G0.800
ethA4326498c.976G>T0.857
ethA4326502c.972T>G0.857
ethA4326510p.Ala322Thr0.857
ethA4326520p.Glu318Asp0.857
ethA4326523c.951A>G0.857
ethA4326985c.489A>G1.000
ethA4326990p.Ile162Val1.000
ethA4326996p.Pro160Thr1.000
ethA4326997c.477C>G1.000
ethA4327001p.Val158Gly1.000
ethA4327014p.Ser154Ala1.000
ethA4327015c.459G>C1.000
ethA4327020p.Ala152Pro1.000
ethA4327025p.Arg150Thr1.000
ethA4327027c.447C>G1.000
ethA4327390c.84C>G1.000
ethA4327396c.78A>G1.000
ethA4327401p.Asp25Asn1.000
ethA4327417c.57C>G1.000
ethA4327420c.54G>A1.000
ethA4327423c.51G>C1.000
ethA4327426c.48A>G1.000
ethA4327438c.36A>G1.000
gid4407603c.600C>T0.938
gid4407609c.594C>G0.947
gid4407652p.Val184Ala0.909
gid4407654c.549C>G0.909
gid4407667p.Ile179Thr0.905

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;