TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5d7652f13d4d6
Sample: 5d7652f13d4d6

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Summary
ID: 5d7652f13d4d6
Date: Mon Sep 9 14:29:53 2019
Strain: lineage6;lineage1.2.2;lineage1.1.3;lineage4.6.2.1;lineage3.1.2.2
Drug-resistance: Drug-resistant

Drug1ResistanceSupporting Mutations (frequency)
IsoniazidRkatG p.Ile335Thr (0.72), katG p.Ile317Leu (0.60)
Rifampicin
EthambutolRembB p.Ala356Val (0.37), embB p.Tyr384Asn (0.28), embB p.Asn399Asp (0.36)
Pyrazinamide
Streptomycin
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage6West-Africa 2AFRI 1RD702
lineage1.2.2Indo-OceanicEAI1RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage4.6.2.1Euro-AmericanT3RD726
lineage3.1.2.2East-African-IndianCASRD750

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5254c.15A>G0.200
gyrB5285p.Ser16Ala0.200
gyrB5294p.Ile19Val0.200
gyrB5314c.75C>T0.278
gyrB5326c.87T>C0.250
gyrB5338c.99C>T0.235
gyrB5341c.102T>C0.235
gyrB5344c.105C>G0.250
gyrB5359c.120C>G0.333
gyrB5362c.123T>C0.294
gyrB5363c.124T>C0.294
gyrB5371c.132T>C0.364
gyrB5396p.Ala53Ser0.333
gyrB5893c.654C>G0.417
gyrB5899c.660C>T0.417
gyrB5902c.663A>G0.417
gyrB5908c.669C>T0.462
gyrB5915p.Val226Thr0.500
gyrB6091c.852G>C0.550
gyrB6115c.876A>G0.714
gyrB6123p.Ala295Glu0.588
gyrB6127c.888G>C0.364
gyrB6172c.933C>T0.815
gyrB6190c.951A>G0.793
gyrB6214c.975G>C0.706
gyrB6238c.999G>A0.722
gyrB6242p.Arg335Lys0.812
gyrB6253c.1014G>C0.810
gyrB6265c.1026C>T0.840
gyrB6280c.1041T>C0.741
gyrB6286c.1047T>C0.679
gyrB6292c.1053G>A0.679
gyrB6298c.1059C>G0.520
gyrB6299c.1060C>T0.520
gyrB6307c.1068T>G0.609
gyrB6316c.1077G>C0.609
gyrB6326p.Ser363Ala0.600
gyrB6331c.1092A>G0.600
gyrB6358c.1119C>G0.565
gyrB6361c.1122G>A0.565
gyrB6362c.1123T>C0.565
gyrB6382c.1143A>G0.630
gyrB6391c.1152G>C0.630
gyrB6397c.1158G>A0.630
gyrB6415c.1176G>C0.650
gyrB6673c.1434A>C0.789
gyrB6674c.1435C>T0.714
gyrB6700c.1461T>C0.706
gyrB6703c.1464G>C0.706
gyrB6706c.1467G>A0.706
gyrB6709c.1470A>G0.706
gyrB6712c.1473G>C0.706
gyrB6730c.1491A>G0.765
gyrB6733c.1494G>A0.765
gyrB6745c.1506T>C0.750
gyrB6751c.1512G>C0.714
gyrB6760c.1521G>C0.643
gyrB6769c.1530C>T0.643
gyrB6775c.1536G>C0.643
gyrB6787c.1548G>A0.667
gyrB6793c.1554T>C0.583
gyrB6797p.Gly520Thr0.583
gyrB6802c.1563G>A0.583
gyrB6808c.1569C>T0.417
gyrB6811c.1572C>T0.583
gyrB6824c.1585C>T0.600
gyrB6911p.Asn558His0.357
gyrB6931c.1692A>G0.462
gyrB6934c.1695A>G0.400
gyrB6949c.1710A>G0.400
gyrB6955c.1716G>A0.357
gyrB6967c.1728T>C0.308
gyrB6970c.1731C>T0.267
gyrB6976c.1737A>G0.222
gyrB6982c.1743A>C0.200
gyrB6985c.1746C>T0.188
gyrB7023p.Leu595Gln0.250
gyrB7030c.1791C>G0.238
gyrB7048c.1809G>A0.200
gyrB7051p.Glu604Asp0.190
gyrB7057c.1818C>T0.200
gyrB7060c.1821T>C0.200
gyrB7066c.1827G>C0.190
gyrB7069c.1830C>T0.190
gyrB7075c.1836T>G0.190
gyrB7076c.1837C>T0.190
gyrB7081c.1842T>G0.227
gyrB7090c.1851C>T0.571
gyrB7093c.1854T>C0.541
gyrB7099c.1860G>A0.590
gyrB7129c.1890T>G0.594
gyrB7132c.1893T>G0.594
gyrB7136c.1897T>C0.679
gyrB7141c.1902T>C0.704
gyrB7147c.1908G>C0.704
gyrB7150c.1911G>C0.704
gyrB7153c.1914G>T0.704
gyrB7156c.1917C>T0.760
gyrB7174c.1935C>T0.750
gyrB7177c.1938G>A0.750
gyrB7178c.1939T>C0.750
gyrB7201c.1962G>A0.762
gyrB7213c.1974G>C0.722
gyrB7216c.1977G>C0.722
gyrB7225c.1986T>C0.667
gyrA7349c.48A>G0.400
gyrA7361c.60C>T0.391
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T0.545
gyrA7394c.93T>C0.545
gyrA7412c.111C>G0.524
gyrA7422c.121C>T0.548
gyrA7433c.132G>C0.537
gyrA7451c.150C>G0.532
gyrA7457c.156T>C0.543
gyrA7469c.168C>G0.575
gyrA7472c.171T>C0.564
gyrA7475c.174A>G0.564
gyrA7480p.Phe60Tyr0.610
gyrA7484c.183T>C0.634
gyrA7490c.189C>G0.620
gyrA7502c.201C>T0.625
gyrA7526c.225G>T0.667
gyrA7532c.231T>C0.652
gyrA7541c.240C>G0.643
gyrA7547c.246C>T0.667
gyrA7585p.Ser95Thr1.000
gyrA7601c.300C>G0.727
gyrA7626c.325C>T0.667
gyrA7631c.330G>C0.634
gyrA7643c.342C>T0.605
gyrA7646c.345C>T0.615
gyrA7655c.354G>C0.531
gyrA7658c.357A>G0.531
gyrA7661c.360C>T0.545
gyrA7664c.363T>C0.545
gyrA7670c.369A>G0.529
gyrA7676c.375G>C0.545
gyrA7679c.378G>C0.571
gyrA7697c.396C>G0.719
gyrA7700c.399G>C0.727
gyrA7706c.405C>G0.710
gyrA7725c.424C>T0.690
gyrA7728c.427A>C0.667
gyrA7763c.462T>C0.692
gyrA7769c.468C>T0.615
gyrA7787c.486G>A0.690
gyrA7793c.492G>A0.720
gyrA7797c.496C>T0.759
gyrA7820c.519G>C0.550
gyrA7832c.531G>T0.500
gyrA7835c.534A>G0.533
gyrA7859c.558A>C0.600
gyrA7865c.564T>C0.538
gyrA7868c.567C>T0.500
gyrA7883c.582G>C0.455
gyrA7884p.Arg195Gly0.455
gyrA7919p.Glu206Asp0.714
gyrA7922c.621T>C0.667
gyrA7923p.His208Tyr0.667
gyrA7940c.639G>A0.812
gyrA7942p.Glu214Ala0.812
gyrA7946c.645C>G0.867
gyrA7947c.646C>T0.867
gyrA7963p.Gly221Glu0.889
gyrA7970c.669T>G0.889
gyrA7979c.678G>C0.882
gyrA7991c.690C>G0.727
gyrA7992p.Ala231Ser0.727
gyrA7997c.696A>G0.727
gyrA7998c.697C>T0.727
gyrA8009c.708A>T0.800
gyrA8012c.711C>G0.750
gyrA8020p.Thr240Ile0.750
gyrA8024c.723T>C0.750
gyrA8027c.726T>C0.750
gyrA8039c.738T>C0.857
gyrA8048c.747C>G0.786
gyrA8054c.753T>C0.750
gyrA8057c.756A>G0.750
gyrA8121c.820T>C0.619
gyrA8126c.825G>C0.636
gyrA8156c.855T>C0.690
gyrA8168c.867A>G0.724
gyrA8177c.876A>C0.724
gyrA8189c.888G>C0.760
gyrA8192c.891C>G0.792
gyrA8198c.897T>C0.792
gyrA8201c.900C>G0.792
gyrA8207c.906T>C0.783
gyrA8219c.918T>C0.722
gyrA8222c.921C>T0.722
gyrA8225c.924T>C0.706
gyrA8231c.930C>G0.706
gyrA8234c.933T>G0.706
gyrA8235c.934T>C0.706
gyrA8253p.Ile318Leu0.857
gyrA8267c.966G>C0.840
gyrA8270c.969G>C0.833
gyrA8283p.Ile328Leu0.696
gyrA8288c.987T>C0.727
gyrA8294c.993T>C0.667
gyrA8324c.1023T>C0.629
gyrA8339c.1038A>G0.605
gyrA8340p.Ala347Ser0.595
gyrA8360c.1059G>A0.543
gyrA8372c.1071G>T0.559
gyrA8375c.1074G>C0.559
gyrA8382p.Leu361Met0.559
gyrA8391p.Tyr364Leu0.423
gyrA8399c.1098T>C0.407
gyrA8402p.Asp367Glu0.407
gyrA8408c.1107A>G0.407
gyrA8417c.1116C>G0.379
gyrA8420c.1119T>C0.379
gyrA8423c.1122G>T0.393
gyrA8426c.1125G>T0.393
gyrA8429c.1128C>G0.440
gyrA8442c.1141C>T0.356
gyrA8447c.1146C>A0.356
gyrA8450c.1149G>A0.356
gyrA8453c.1152A>C0.348
gyrA8462c.1161A>C0.640
gyrA8480c.1179C>T0.655
gyrA8486c.1185T>C0.667
gyrA8489c.1188A>G0.571
gyrA8492c.1191G>C0.571
gyrA8504c.1203G>C0.667
gyrA8516c.1215T>C0.636
gyrA8519c.1218A>G0.560
gyrA8520c.1219C>T0.560
gyrA8531c.1230G>T0.615
gyrA8535p.Glu412Gln0.615
gyrA8543c.1242C>T0.600
gyrA8546c.1245T>C0.600
gyrA8555c.1254G>C0.652
gyrA8561c.1260A>C0.652
gyrA8585c.1284C>T0.650
gyrA8588c.1287G>A0.650
gyrA8619c.1318T>C0.700
gyrA8624c.1323G>T0.684
gyrA8627c.1326C>A0.632
gyrA8636c.1335A>C0.632
gyrA8642c.1341A>G0.632
gyrA8655p.Ile452Val0.632
gyrA8672c.1371A>G0.688
gyrA8678c.1377G>A0.688
gyrA8694c.1393C>T0.647
gyrA8711c.1410A>C0.556
gyrA8714c.1413A>G0.556
gyrA8717c.1416C>G0.556
gyrA8720c.1419G>A0.556
gyrA8729c.1428T>C0.632
gyrA8747c.1446A>G0.256
gyrA8765p.Asp488Glu0.400
gyrA8767p.Arg489Lys0.400
gyrA8779p.Asp493Ala0.385
gyrA8786c.1485T>C0.357
gyrA8789c.1488C>T0.357
gyrA8792c.1491G>C0.357
gyrA8798c.1497C>T0.471
gyrA8810c.1509A>C0.500
gyrA8813p.Asp504Glu0.500
gyrA8818p.Ser506Asn0.529
gyrA8829c.1528T>C0.611
gyrA8840c.1539C>G0.591
gyrA8852c.1551T>C0.611
gyrA8858c.1557T>G0.632
gyrA8870c.1569G>C0.625
gyrA8873c.1572A>T0.625
gyrA8876c.1575C>T0.375
gyrA8888c.1587C>G0.676
gyrA8897c.1596T>C0.694
gyrA8903c.1602T>C0.686
gyrA8915c.1614A>G0.767
gyrA8924c.1623C>T0.733
gyrA8930c.1629C>G0.731
gyrA8933c.1632G>C0.731
gyrA8936c.1635G>A0.704
gyrA8939c.1638T>C0.704
gyrA8942c.1641G>C0.704
gyrA8946c.1645T>C0.731
gyrA8983p.Cys561Ser0.629
gyrA8987c.1686C>G0.629
gyrA8990c.1689C>G0.629
gyrA8996c.1695T>C0.595
gyrA8998p.Leu566Trp0.605
gyrA9003c.1702C>T0.600
gyrA9023c.1722A>C0.641
gyrA9029c.1728T>A0.548
gyrA9032c.1731T>C0.533
gyrA9035c.1734G>C0.517
gyrA9038c.1737C>G0.556
gyrA9050p.Asp583Glu0.605
gyrA9051c.1750T>C0.590
gyrA9062c.1761C>A0.609
gyrA9071c.1770G>C0.617
gyrA9074c.1773G>C0.644
gyrA9080c.1779G>T0.638
gyrA9089c.1788G>C0.634
gyrA9101c.1800A>G0.658
gyrA9104c.1803C>A0.676
gyrA9110c.1809G>A0.684
gyrA9128c.1827C>A0.682
gyrA9143c.1842T>C1.000
gyrA9147p.Gly616Ser0.483
gyrA9153p.Thr618Glu0.444
gyrA9161c.1860C>G0.444
gyrA9164c.1863G>C0.444
gyrA9167c.1866C>T0.400
gyrA9182c.1881T>C0.414
gyrA9183p.Arg628Lys0.414
gyrA9197c.1896G>C0.605
gyrA9230c.1929T>C0.595
gyrA9236c.1935G>C0.595
gyrA9242c.1941A>C0.600
gyrA9248c.1947G>C0.619
gyrA9252p.Val651Ile0.605
gyrA9266c.1965C>T0.521
gyrA9284c.1983T>C0.393
gyrA9287c.1986G>C0.393
gyrA9291c.1990C>T0.414
gyrA9296c.1995T>C0.481
gyrA9304p.Gly668Glu1.000
gyrA9308p.Asp669Glu0.464
gyrA9315c.2014C>T0.517
gyrA9326c.2025G>T0.600
gyrA9338c.2037G>A0.520
gyrA9341c.2040C>G0.520
gyrA9345c.2044A>C0.500
gyrA9383c.2082T>C0.440
gyrA9386c.2085T>C0.440
gyrA9395c.2094G>C0.435
gyrA9398c.2097T>C0.323
gyrA9419c.2118T>C0.364
gyrA9420p.Ile707Glu0.364
gyrA9435c.2134C>T0.381
gyrA9518c.2217A>G0.235
gyrA9521c.2220C>T0.235
gyrA9527c.2226A>C0.235
gyrA9578c.2277C>T0.600
gyrA9584p.Arg761Ser0.545
gyrA9585c.2284T>C0.545
gyrA9590c.2289T>G0.571
gyrA9593c.2292G>A0.565
gyrA9602c.2301T>C0.636
gyrA9626c.2325T>C0.389
gyrA9629c.2328C>G0.389
gyrA9630p.Val777Ile0.389
gyrA9635c.2334T>C0.412
gyrA9638c.2337C>G0.412
gyrA9644c.2343T>C0.412
gyrA9650c.2349G>C0.368
gyrA9662c.2361G>C0.304
gyrA9665c.2364A>G0.200
gyrA9668c.2367C>G0.273
gyrA9674c.2373T>C0.273
gyrA9683c.2382G>C0.286
gyrA9689c.2388G>A0.286
gyrA9701c.2400T>C0.300
gyrA9704c.2403T>C0.278
gyrA9716c.2415T>C0.250
gyrA9722c.2421C>T0.250
rpoB759818c.12C>T0.615
rpoB760056c.250C>T0.538
rpoB760070c.264T>G0.500
rpoB760091c.285G>C0.571
rpoB760101c.295T>C0.692
rpoB760109c.303C>T0.750
rpoB760112c.306T>C0.750
rpoB760118c.312T>C0.765
rpoB760121c.315T>C0.765
rpoB760130p.Asp108Glu0.765
rpoB760139c.333A>G0.812
rpoB760142c.336C>G0.867
rpoB760145c.339C>G0.867
rpoB760181c.375T>A0.810
rpoB760184c.378A>G0.800
rpoB760196c.390C>G0.789
rpoB760235c.429T>C0.625
rpoB760244c.438G>C0.500
rpoB760274c.468G>A0.476
rpoB760295c.489C>T0.519
rpoB760307c.501T>C0.483
rpoB760310c.504G>C0.452
rpoB760328c.522G>C0.500
rpoB760331c.525G>C0.538
rpoB760337c.531C>G0.538
rpoB760340c.534G>T0.556
rpoB760358c.552C>G0.538
rpoB760361c.555T>C0.538
rpoB760370c.564C>G0.556
rpoB760376p.Asp190Glu0.536
rpoB760380p.Thr192Leu0.536
rpoB760403c.597C>T0.531
rpoB760412c.606C>T0.500
rpoB760414p.Gly203Asp0.500
rpoB760418c.612G>C0.500
rpoB760424c.618C>G0.469
rpoB760430c.624T>C0.457
rpoB760472c.666C>T0.378
rpoB760475c.669A>G0.361
rpoB760478c.672C>T0.333
rpoB760481c.675G>T0.333
rpoB760484c.678A>G0.333
rpoB760493c.687C>G0.342
rpoB760520c.714C>G0.303
rpoB760522p.Ser239Asn0.219
rpoB760526c.720G>A0.219
rpoB760532c.726T>C0.226
rpoB760533p.Val243Thr0.250
rpoB760547c.741G>C0.429
rpoB760563p.Arg253Met0.500
rpoB760591p.Val262Ala0.643
rpoB760601c.795C>T0.607
rpoB760611c.805T>C0.577
rpoB760622c.816C>T0.609
rpoB760646c.840C>G0.636
rpoB760649c.843G>C0.652
rpoB760655c.849A>G0.593
rpoB760661c.855A>C0.593
rpoB760670c.864G>C0.640
rpoB760674c.868T>C0.609
rpoB760679c.873A>G0.545
rpoB760683c.877T>C0.571
rpoB760724c.918T>C0.571
rpoB760730c.924T>C0.548
rpoB760748c.942C>G0.586
rpoB760757c.951T>C0.586
rpoB760759p.Val318Ala0.586
rpoB760769c.963C>G0.600
rpoB760793c.987A>G0.633
rpoB760805c.999G>C0.640
rpoB760817c.1011A>G0.640
rpoB760820c.1014T>C0.625
rpoB760826c.1020C>G0.600
rpoB760830c.1024T>C0.640
rpoB760841c.1035T>C0.560
rpoB760845p.Thr347Pro0.542
rpoB760856c.1050C>G0.667
rpoB760916c.1110C>G0.412
rpoB760919c.1113C>G0.389
rpoB760925c.1119T>C0.389
rpoB760928c.1122G>C0.389
rpoB760931c.1125C>G0.389
rpoB760937c.1131G>A0.450
rpoB760946c.1140A>G0.476
rpoB760973c.1167G>C0.474
rpoB760982c.1176G>T0.444
rpoB760985c.1179G>T0.444
rpoB760991c.1185G>T0.471
rpoB761006c.1200C>T0.375
rpoB761015c.1209G>C0.333
rpoB761021c.1215G>C0.348
rpoB761027c.1221A>G0.364
rpoB761036c.1230G>C0.348
rpoB761037c.1231T>C0.348
rpoB761051c.1245G>T0.263
rpoB761057c.1251G>C0.263
rpoB761060c.1254C>G0.263
rpoB761063c.1257C>G0.263
rpoB761096c.1290G>C0.300
rpoB761097c.1291A>T0.250
rpoB761102c.1296A>G0.316
rpoB761132c.1326G>T0.474
rpoB761133c.1327T>C0.474
rpoB761150c.1344A>C0.450
rpoB761168c.1362C>G0.688
rpoB761180c.1374A>C0.730
rpoB761189c.1383T>G0.771
rpoB761192c.1386C>G0.765
rpoB761195c.1389G>C0.771
rpoB761198c.1392G>C0.778
rpoB761240c.1434C>T0.771
rpoB761249c.1443A>G0.750
rpoB761255c.1449T>C0.769
rpoB761261c.1455G>T0.784
rpoB761264c.1458C>G0.763
rpoB761282c.1476C>G0.733
rpoB761327c.1521A>G0.679
rpoB761345c.1539G>T0.656
rpoB761354c.1548C>T0.618
rpoB761360c.1554T>C0.613
rpoB761362p.Ser519Thr0.613
rpoB761374p.Val523Glu0.676
rpoB761414c.1608A>G0.600
rpoB761423c.1617T>C0.633
rpoB761432c.1626C>T0.552
rpoB761435c.1629T>C0.586
rpoB761438c.1632G>C0.586
rpoB761444c.1638T>C0.548
rpoB761452p.Val549Glu0.531
rpoB761457p.Pro551Ser0.515
rpoB761465c.1659G>A0.515
rpoB761471c.1665C>T0.548
rpoB761477c.1671C>T0.571
rpoB761492c.1686G>C0.500
rpoB761504c.1698C>G0.520
rpoB761510c.1704T>C0.500
rpoB761531c.1725C>G0.394
rpoB761537c.1731C>G0.353
rpoB761558c.1752C>G0.487
rpoB761570c.1764T>C0.474
rpoB761573c.1767C>G0.459
rpoB761579c.1773G>C0.472
rpoB761606c.1800C>G0.500
rpoB761612c.1806G>T0.500
rpoB761615c.1809A>C0.385
rpoB761636c.1830G>T0.535
rpoB761645c.1839C>A0.556
rpoB761648c.1842T>C0.556
rpoB761666c.1860G>C0.569
rpoB761690c.1884G>C0.571
rpoB761725p.Glu640Ala0.485
rpoB761732c.1926C>G0.485
rpoB761735c.1929C>G0.471
rpoB761750c.1944G>C0.528
rpoB761765c.1959T>C0.533
rpoB761772p.His656Ala0.464
rpoB761778p.Asn658Asp0.423
rpoB761791p.Arg662His0.423
rpoB761813c.2007T>C0.381
rpoB761828c.2022C>T0.238
rpoB761834c.2028T>C0.263
rpoB761837c.2031C>T0.238
rpoB761848p.Cys681Ser0.227
rpoB761852c.2046C>G0.250
rpoB761858c.2052G>C0.238
rpoB761873c.2067A>C0.158
rpoB761885c.2079T>C0.292
rpoB761891c.2085G>C0.333
rpoB761909c.2103T>C0.318
rpoB761912c.2106T>C0.316
rpoB761913p.Asp703Gln0.350
rpoB761916p.Asp704Asn0.350
rpoB761921c.2115C>T0.412
rpoB761930c.2124G>C0.444
rpoB761954c.2148C>G0.700
rpoB762008c.2202C>G0.739
rpoB762014c.2208C>T0.708
rpoB762047c.2241G>A0.727
rpoB762053c.2247T>C0.727
rpoB762062c.2256T>C0.773
rpoB762065c.2259T>C0.773
rpoB762083c.2277T>C0.810
rpoB762086c.2280G>C0.810
rpoB762101c.2295C>G0.810
rpoB762114p.Ile770Val0.833
rpoB762131c.2325C>G0.850
rpoB762134c.2328C>G0.850
rpoB762143c.2337T>C0.938
rpoB762167c.2361T>C1.000
rpoB762185c.2379G>C0.846
rpoB762233c.2427G>T0.714
rpoB762254c.2448T>G0.548
rpoB762257c.2451C>G0.548
rpoB762266c.2460T>C0.531
rpoB762281c.2475G>A0.531
rpoB762284c.2478G>C0.531
rpoB762293c.2487T>C0.500
rpoB762317c.2511A>G0.481
rpoB762338c.2532T>C0.500
rpoB762341c.2535G>C0.519
rpoB762347c.2541T>C0.480
rpoB762362p.Glu852Asp0.455
rpoB762369c.2563T>C0.455
rpoB762395c.2589G>C0.438
rpoB762398c.2592T>C0.538
rpoB762401c.2595G>C0.538
rpoB762404c.2598T>C0.700
rpoB762410c.2604T>C0.769
rpoB762416c.2610A>G0.769
rpoB762431c.2625C>T0.769
rpoB762449c.2643C>A0.833
rpoB762491c.2685T>C0.500
rpoB762509c.2703T>G0.500
rpoB762510p.Ala902Pro0.400
rpoB762533c.2727T>C0.467
rpoB762536c.2730T>C0.412
rpoB762537c.2731T>C0.412
rpoB762551c.2745C>T0.389
rpoB762563c.2757G>A0.400
rpoB762581c.2775T>C0.333
rpoB762587c.2781G>A0.333
rpoB762710c.2904G>T0.333
rpoB762729p.Gln975Lys0.429
rpoB762736p.Ala977Glu0.429
rpoB762776c.2970C>G0.467
rpoB762782c.2976T>C0.429
rpoB762789p.Leu995Met0.400
rpoB762794c.2988C>G0.400
rpoB762795p.Asp997Asn0.400
rpoB762812c.3006C>G0.533
rpoB762813p.Met1003Val0.562
rpoB762818c.3012C>G0.500
rpoB762827c.3021G>C0.524
rpoB762833c.3027C>T0.545
rpoB762857c.3051C>G0.538
rpoB762860c.3054G>C0.519
rpoB762902c.3096C>T0.581
rpoB762917c.3111C>T0.594
rpoB762929c.3123G>T0.588
rpoB762962c.3156C>T0.600
rpoB762983c.3177C>G0.636
rpoB762995c.3189G>T0.696
rpoB763031c.3225T>C1.000
rpoB763034c.3228C>G0.562
rpoB763040c.3234C>G0.643
rpoB763050c.3244C>T0.538
rpoB763070c.3264T>C0.500
rpoB763082c.3276C>T0.417
rpoB763085c.3279C>G0.556
rpoB763115c.3309T>C0.667
rpoB763127c.3321G>C0.667
rpoB763166c.3360A>G0.667
rpoB763169c.3363A>G0.684
rpoB763202c.3396A>C0.722
rpoB763205c.3399G>T0.688
rpoB763206c.3400A>T0.688
rpoB763226c.3420A>G0.750
rpoB763238c.3432T>C0.688
rpoB763241c.3435G>A0.688
rpoB763250c.3444C>T0.846
rpoB763253c.3447G>T1.000
rpoB763262c.3456C>A1.000
rpoB763265c.3459G>A0.833
rpoB763283c.3477T>C0.833
rpoB763284c.3478C>T0.833
rpoB763289c.3483C>G0.714
rpoC763351c.-19T>C0.462
rpoC763352c.-18T>A0.462
rpoC763402c.33C>T0.267
rpoC763409c.40C>T0.267
rpoC763414c.45T>G0.308
rpoC763441c.72C>T0.400
rpoC763444c.75T>C0.400
rpoC763456c.87A>G0.500
rpoC763486c.117T>G0.400
rpoC763528c.159G>A0.364
rpoC763546c.177A>G0.478
rpoC763570c.201G>C0.542
rpoC763594c.225C>T0.571
rpoC763603c.234C>T0.593
rpoC763618c.249C>T0.654
rpoC763636c.267T>C0.680
rpoC763660c.291T>G0.667
rpoC763669c.300C>G0.600
rpoC763675c.306C>G0.667
rpoC763703c.334T>A0.476
rpoC763709c.340C>T0.500
rpoC763714c.345G>C0.538
rpoC763726c.357C>T0.621
rpoC763732c.363C>G0.600
rpoC763741c.372C>T0.613
rpoC763744c.375G>C0.613
rpoC763765c.396T>G0.655
rpoC763771c.402C>T0.697
rpoC763780c.411C>G0.657
rpoC763792p.Glu141Asp0.647
rpoC763801c.432C>G0.583
rpoC763807c.438T>C0.568
rpoC763836p.Ala156Val0.656
rpoC763851p.Ala161Gly0.519
rpoC763855c.486C>T0.536
rpoC763858c.489A>G0.536
rpoC763872p.Gly168Ala0.452
rpoC763876p.Glu169Asp0.433
rpoC763879c.510A>G0.467
rpoC763888c.519G>C0.423
rpoC763891c.522G>C0.423
rpoC763894c.525A>G0.414
rpoC763936c.567C>G0.576
rpoC763939c.570G>A0.576
rpoC763951c.582G>A0.688
rpoC763963c.594C>G0.719
rpoC763967p.Gly200Ser0.719
rpoC763972c.603C>T0.719
rpoC763987c.618C>T0.688
rpoC763996c.627T>C0.714
rpoC764005c.636G>C0.765
rpoC764011c.642T>C0.778
rpoC764013p.Glu215Ala0.222
rpoC764024c.655T>C0.794
rpoC764040p.Ser224Thr0.690
rpoC764044c.675T>G0.690
rpoC764059c.690G>T0.667
rpoC764083c.714A>G0.600
rpoC764098c.729A>G0.538
rpoC764101c.732C>G0.577
rpoC764140c.771C>T0.559
rpoC764159c.790C>T0.419
rpoC764167c.798G>A0.433
rpoC764188c.819A>G0.424
rpoC764195p.Ser276Ile0.367
rpoC764215c.846A>C0.438
rpoC764218c.849C>T0.424
rpoC764242c.873C>T0.455
rpoC764245c.876C>A0.469
rpoC764246c.877C>T0.455
rpoC764263c.894G>C0.548
rpoC764266c.897T>C0.586
rpoC764278c.909A>G0.600
rpoC764317c.948C>G0.600
rpoC764320c.951C>G0.600
rpoC764341c.972G>T0.290
rpoC764347c.978G>A0.290
rpoC764353c.984G>T0.290
rpoC764362c.993C>T0.290
rpoC764365c.996C>T0.516
rpoC764371c.1002G>T0.273
rpoC764377c.1008C>G0.333
rpoC764380c.1011G>C0.500
rpoC764381c.1012T>A0.500
rpoC764387c.1018T>C0.526
rpoC764405c.1036A>C0.600
rpoC764428c.1059G>C0.538
rpoC764431c.1062G>C0.520
rpoC764434c.1065A>G0.520
rpoC764446c.1077T>C0.423
rpoC764449c.1080G>C0.423
rpoC764452c.1083T>C0.423
rpoC764458c.1089G>C0.550
rpoC764461c.1092A>G0.550
rpoC764497c.1128A>G0.500
rpoC764503c.1134G>C0.520
rpoC764521c.1152T>C0.478
rpoC764527c.1158C>T0.522
rpoC764536c.1167G>T0.550
rpoC764539c.1170C>G0.550
rpoC764554c.1185C>T0.632
rpoC764575c.1206T>G0.500
rpoC764578c.1209C>G0.500
rpoC764593c.1224C>T0.545
rpoC764605c.1236G>A0.545
rpoC764626c.1257C>T0.708
rpoC764650c.1281G>T0.750
rpoC764668c.1299C>T0.735
rpoC764686c.1317C>T0.686
rpoC764752c.1383G>C0.742
rpoC764764c.1395T>C0.714
rpoC764782c.1413C>T0.350
rpoC764797c.1428G>C0.298
rpoC764803c.1434C>G0.586
rpoC764809c.1440C>T0.552
rpoC764815c.1446A>G0.567
rpoC764858c.1489T>C0.639
rpoC764887c.1518G>C0.559
rpoC764888c.1519T>C0.559
rpoC764896c.1527C>T0.559
rpoC764902c.1533C>T0.541
rpoC764911c.1542A>G0.545
rpoC764923c.1554A>G0.634
rpoC764932c.1563C>G0.676
rpoC764948c.1579T>C0.750
rpoC764968c.1599T>C0.816
rpoC765007c.1638T>G0.646
rpoC765008c.1639T>C0.638
rpoC765013c.1644C>T0.638
rpoC765019c.1650A>G0.608
rpoC765040c.1671T>C0.423
rpoC765041c.1672T>C0.423
rpoC765047c.1678T>C0.360
rpoC765052c.1683C>G0.391
rpoC765053c.1684T>A0.391
rpoC765065c.1696C>T0.467
rpoC765073c.1704G>C0.467
rpoC765076c.1707A>G0.467
rpoC765079c.1710T>C0.467
rpoC765082c.1713G>C0.452
rpoC765089c.1720T>C0.457
rpoC765103c.1734G>A0.474
rpoC765121c.1752G>T0.500
rpoC765208c.1839T>C0.292
rpoC765223c.1854G>C0.280
rpoC765233p.Ala622Ser0.269
rpoC765247c.1878C>G0.233
rpoC765248c.1879T>C0.250
rpoC765251c.1882A>T0.259
rpoC765278c.1909C>T0.407
rpoC765283c.1914C>G0.407
rpoC765292c.1923G>T0.407
rpoC765300p.Val644Ala0.387
rpoC765319c.1950A>G0.447
rpoC765328p.His653Gln0.459
rpoC765330p.Ser654Asn0.459
rpoC765334c.1965C>T0.444
rpoC765343c.1974G>A0.500
rpoC765352c.1983G>C0.394
rpoC765367c.1998C>G0.457
rpoC765370c.2001G>C0.500
rpoC765383p.Met672Leu0.533
rpoC765391c.2022C>T0.536
rpoC765406c.2037G>T0.524
rpoC765409c.2040T>C0.500
rpoC765412c.2043T>C0.545
rpoC765421c.2052C>G0.600
rpoC765452p.Ala695Ser0.708
rpoC765466c.2097C>T0.571
rpoC765478c.2109T>C0.576
rpoC765493c.2124G>C0.600
rpoC765499c.2130C>G0.636
rpoC765508c.2139C>G0.647
rpoC765517c.2148C>G0.611
rpoC765529c.2160C>T0.649
rpoC765541c.2172C>G0.636
rpoC765553c.2184C>T0.600
rpoC765556c.2187G>C0.576
rpoC765562c.2193G>C0.556
rpoC765578c.2209C>T0.556
rpoC765622p.Glu751Asp0.667
rpoC765625c.2256C>T0.625
rpoC765628c.2259G>C0.625
rpoC765658c.2289C>T0.633
rpoC765670c.2301C>T0.630
rpoC765700c.2331T>C0.692
rpoC765728p.Gln787Lys0.643
rpoC765734c.2365T>C0.643
rpoC765739c.2370G>C0.679
rpoC765752p.Asp795Ser0.609
rpoC765772c.2403C>G0.550
rpoC765784c.2415C>G0.632
rpoC765790c.2421C>T0.650
rpoC765793c.2424C>G0.650
rpoC765796c.2427C>T0.650
rpoC765814c.2445A>G0.625
rpoC765826c.2457T>C0.640
rpoC765835c.2466C>T0.593
rpoC765883c.2514C>G0.680
rpoC765886c.2517C>G0.652
rpoC765892c.2523T>C0.652
rpoC765934c.2565C>T0.484
rpoC765967c.2598C>T0.516
rpoC765982c.2613C>G0.560
rpoC765994c.2625A>T0.565
rpoC766012c.2643C>G0.600
rpoC766021c.2652G>C0.586
rpoC766061p.Val898Ile0.500
rpoC766082p.Ala905Gln0.417
rpoC766093c.2724C>A0.455
rpoC766095p.Thr909Ser0.400
rpoC766105c.2736C>T0.448
rpoC766123c.2754C>A0.484
rpoC766129c.2760C>G0.469
rpoC766135c.2766G>A0.469
rpoC766141c.2772C>T0.414
rpoC766142c.2773C>T0.414
rpoC766147c.2778C>T0.357
rpoC766148p.Thr927Ala0.385
rpoC766168c.2799C>G0.375
rpoC766270c.2901G>C0.647
rpoC766273c.2904T>C0.647
rpoC766274p.Ala969Thr0.647
rpoC766280p.Ser971Gly0.688
rpoC766288c.2919C>G0.684
rpoC766309c.2940G>A0.700
rpoC766315c.2946C>G0.684
rpoC766321c.2952C>G0.667
rpoC766348c.2979A>G0.600
rpoC766369c.3000C>G0.625
rpoC766381c.3012C>T0.667
rpoC766384c.3015A>G0.667
rpoC766393c.3024C>G0.647
rpoC766402c.3033C>G0.667
rpoC766408c.3039C>T0.619
rpoC766426c.3057C>T0.550
rpoC766456c.3087C>G0.471
rpoC766486c.3117A>G0.500
rpoC766492c.3123T>C0.500
rpoC766522c.3153C>G0.556
rpoC766528c.3159T>C0.579
rpoC766530p.Arg1054Gln0.579
rpoC766549c.3180G>C0.619
rpoC766573c.3204T>C0.667
rpoC766585c.3216T>C0.615
rpoC766594c.3225G>C0.615
rpoC766607p.Ile1080Leu0.621
rpoC766630c.3261G>T0.657
rpoC766660c.3291G>A0.657
rpoC766666c.3297C>G0.625
rpoC766672c.3303T>C0.656
rpoC766700c.3331C>T0.690
rpoC766726c.3357T>C0.613
rpoC766733c.3364C>T0.655
rpoC766738c.3369G>C0.613
rpoC766741c.3372G>C0.613
rpoC766750c.3381C>G0.567
rpoC766765c.3396A>C0.559
rpoC766774c.3405T>C0.611
rpoC766798c.3429C>G0.514
rpoC766801c.3432C>G0.514
rpoC766804c.3435A>G0.500
rpoC766843c.3474T>G0.417
rpoC766864c.3495G>C0.455
rpoC766876c.3507C>T0.560
rpoC766883p.Ser1172Ala0.542
rpoC766894c.3525T>C0.600
rpoC766895c.3526T>C0.600
rpoC766900c.3531T>C0.600
rpoC766903c.3534C>T0.571
rpoC766918c.3549C>T0.417
rpoC766933c.3564A>G0.500
rpoC766945c.3576A>G0.462
rpoC766955p.Glu1196Lys0.417
rpoC766996c.3627C>G0.600
rpoC767002c.3633G>C0.600
rpoC767009c.3640T>A0.333
rpoC767014c.3645G>C0.333
rpoC767033c.3664T>A0.500
rpoC767059c.3690T>G0.552
rpoC767062c.3693C>A0.552
rpoC767098c.3729T>C0.457
rpoC767119c.3750A>G0.452
rpoC767134c.3765C>A0.487
rpoC767158c.3789T>A0.450
rpoC767167c.3798C>G0.436
rpoC767180p.Ala1271Gln0.421
rpoC767191c.3822C>G0.400
rpoC767206c.3837C>G0.421
rpoC767209c.3840T>C0.421
rpoC767221c.3852C>G0.400
rpoC767230c.3861G>C0.406
rpoC767233c.3864T>C0.406
rpoC767263c.3894T>G0.421
rpoC767264p.Ala1299Gln0.421
rpoC767278c.3909T>C0.444
rpoC767281c.3912C>G0.444
rpoC767284c.3915C>T0.444
rpsL781353c.-207T>C0.667
rpsL781358c.-202G>C0.667
rpsL781372c.-188T>A0.577
rpsL781395c.-165T>C1.000
rpsL781488c.-72G>A0.818
rpsL781571c.12C>T0.632
rpsL781595c.36T>C0.562
rpsL781598c.39G>C0.562
rpsL781605p.Ile16Val0.600
rpsL781608p.Ser17Ala0.529
rpsL781616c.57C>T0.550
rpsL781628c.69T>C0.583
rpsL781655c.96T>C0.480
rpsL781658c.99A>G0.458
rpsL781682c.123T>C0.524
rpsL781715c.156T>C0.304
rpsL781718c.159C>G0.304
rpsL781721c.162C>T0.304
rpsL781728c.169T>C0.304
rpsL781736c.177T>C0.308
rpsL781751c.192G>C0.346
rpsL781754c.195G>C0.346
rpsL781760c.201T>C0.333
rpsL781766c.207C>T0.333
rpsL781772c.213C>G0.304
rpsL781793c.234G>C0.304
rpsL781808c.249C>T0.364
rpsL781832c.273T>G0.263
rpsL781835c.276T>C0.278
rpsL781859c.300T>G0.381
rpsL781865c.306G>C0.391
rpsL781868c.309T>C0.391
rpsL781871c.312G>C0.417
rpsL781883c.324G>A0.409
rpsL781886c.327C>T0.500
rpsL781892c.333A>G0.500
rpsL781898c.339A>T0.550
rpsL781916c.357T>C0.583
rpsL781929p.Gly124Ser0.625
rpsL781933374G>A0.615
rplC800829c.21C>G0.250
rplC800844c.36T>C0.385
rplC800856c.48A>G0.385
rplC800865c.57A>G0.273
rplC800867p.Ser20Asn0.273
rplC800872c.64A>C0.273
rplC800877c.69A>C0.273
rplC800880c.72A>G0.273
rplC800901c.93C>G0.417
rplC800910c.102C>T0.417
rplC800913c.105G>A0.417
rplC800916c.108A>G0.417
rplC800919c.111C>G0.417
rplC800931c.123G>C0.417
rplC800934c.126C>G0.417
rplC800937c.129A>G0.500
rplC800946c.138T>A0.462
rplC800949c.141T>C0.462
rplC800962p.Leu52Val0.500
rplC800970c.162T>C0.583
rplC801171c.363A>G0.348
rplC801180c.372C>G0.400
rplC801195c.387G>C0.429
rplC801201c.393C>T0.407
rplC801207c.399C>T0.417
rplC801210c.402T>C0.440
rplC801222c.414T>C0.542
rplC801228c.420T>C0.476
rplC801231c.423C>T0.542
rplC801246c.438C>T0.655
rplC801255c.447C>A0.667
rplC801267c.459A>C0.654
rplC801270c.462T>C0.654
rplC801273c.465C>G0.586
rplC801279c.471G>C0.586
rplC801285c.477G>A0.567
rplC801309c.501C>G0.567
rplC801312c.504G>C0.536
rplC801324c.516T>C0.531
rplC801330c.522G>T0.400
rplC801333c.525G>C0.400
rplC801339c.531T>G0.417
rplC801341p.Leu178Gln0.417
rplC801348c.540T>G0.478
rplC801349p.Leu181Val0.478
rplC801357c.549T>C0.618
rplC801372c.564G>A0.622
rplC801385c.577C>T0.595
rplC801402c.594T>C0.583
rplC801405c.597T>C0.583
rplC801408c.600C>A0.595
rplC801423c.615G>C0.667
rplC801426c.618C>T0.667
rplC801427p.Met207Val0.667
rplC801437p.Ser210Thr0.611
rplC801461653G>A0.568
embR1416222p.Phe376Leu0.188
embR1416234p.Cys372Gly0.286
embR1416364c.984G>A0.231
embR1416386p.Asp321Ala0.231
embR1416388c.960T>C0.231
embR1416393p.Val319Ile0.250
embR1416790c.558C>A0.200
embR1416910c.438A>G0.231
embR1416921p.Arg143Ala0.231
embR1416924c.424A>G0.231
embR1416930p.Ala140Thr0.308
embR1416936c.412G>A0.308
embR1416940c.408G>A0.308
rrs1471896r.51t>c0.974
rrs1471900r.55c>t0.974
rrs1471914r.69a>g0.850
rrs1472061r.216a>t0.300
rrs1472075r.230a>g0.300
rrs1472117r.272a>t0.815
rrs1472127r.282c>t0.961
rrs1472129r.284g>c0.961
rrs1472137r.292g>a0.962
rrs1472150r.305t>a0.956
rrs1472151r.306c>t0.956
rrs1472172r.327t>c0.960
rrs1472203r.358g>a0.947
rrs1472216r.371caatgggcgcaa>c0.154
rrs1472286r.441c>g0.188
rrs1472289r.444t>g0.188
rrs1472290r.445c>g0.188
rrs1472313r.468g>a0.214
rrs1472315r.470t>g0.214
rrs1472324r.479g>c0.267
rrs1472325r.480g>c0.267
rrs1472328r.483g>c0.267
rrs1472338r.493a>c0.679
rrs1472344r.499c>t0.925
rrs1472379r.534t>g0.937
rrs1472382r.537g>a0.936
rrs1472400r.555c>t0.940
rrs1472412r.567a>c0.522
rrs1472415r.570t>g0.294
rrs1472508r.663t>c0.588
rrs1472517r.672t>a0.714
rrs1472518r.673g>c0.811
rrs1472530r.685g>a0.969
rrs1472537r.692c>t0.969
rrs1472541r.696t>g0.965
rrs1472544r.699c>g0.965
rrs1472545r.700a>t0.965
rrs1472557r.712g>a0.970
rrs1472571r.726g>c0.965
rrs1472573r.728c>t0.965
rrs1472579r.734g>c0.963
rrs1472581r.736a>t0.960
rrs1472598r.753a>c0.972
rrs1472616r.771g>a0.976
rrs1472655r.810g>a0.986
rrs1472658r.813g>a0.981
rrs1472661r.816a>g1.000
rrs1472690r.845c>g0.833
rrs1472697r.852t>a0.899
rrs1472700r.855c>t0.907
rrs1472705r.860g>a0.912
rrs1472713r.868t>c0.973
rrs1472716r.871c>t0.973
rrs1472733r.888g>c0.966
rrs1472734r.889c>t0.966
rrs1472741r.896g>a0.962
rrs1472742r.897c>g0.962
rrs1472744r.899a>g0.959
rrs1472767r.922g>a0.958
rrs1472779r.934g>a0.947
rrs1472781r.936c>t0.944
rrs1472786r.941c>t0.952
rrs1472793r.948a>t0.949
rrs1472803r.958t>a0.948
rrs1472824r.979t>a0.480
rrs1472827r.982g>t0.263
rrs1472828r.983t>c0.294
rrs1472847r.1002g>c0.200
rrs1472848r.1003t>g0.200
rrs1472849r.1004c>g0.200
rrs1472850r.1005t>c0.200
rrs1472857r.1012a>g0.167
rrs1472858r.1013g>t0.167
rrs1472859r.1014g>c0.167
rrs1472860r.1015c>g0.167
rrs1472895r.1050c>t0.950
rrs1472957r.1112c>t0.925
rrs1472959r.1114t>a0.556
rrs1472969r.1124a>g0.170
rrs1472973r.1128a>g0.573
rrs1472982r.1137g>c0.959
rrs1472987r.1142g>t0.833
rrs1472989r.1144g>a0.969
rrs1473002r.1157g>t0.955
rrs1473004r.1159t>a0.955
rrs1473008r.1163c>a0.955
rrs1473009r.1164t>c0.955
rrs1473020r.1175t>c0.988
rrs1473035r.1190g>a0.984
rrs1473053r.1208t>a0.959
rrs1473056r.1211a>t0.958
rrs1473062r.1217t>a0.962
rrs1473068r.1223a>g0.957
rrs1473070r.1225g>a0.961
rrs1473088r.1243a>g0.643
rrs1473093r.1248c>a0.610
rrs1473094r.1249t>a0.634
rrs1473099r.1254t>g0.634
rrs1473100r.1255g>a0.634
rrs1473102r.1257c>t0.650
rrs1473105r.1260g>a0.175
rrs1473107r.1262g>a0.650
rrs1473110r.1265t>g0.650
rrs1473111r.1266a>g0.667
rrs1473121r.1276t>c0.945
rrs1473122r.1277t>a0.945
rrs1473145r.1300c>t0.926
rrs1473147r.1302g>c0.920
rrs1473148r.1303g>a0.920
rrs1473150r.1305t>g0.920
rrs1473161r.1316a>c0.902
rrs1473163r.1318c>t0.911
rrs1473164r.1319c>g0.902
rrs1473166r.1321g>a0.920
rrs1473177r.1332g>a0.926
rrs1473179r.1334c>t0.919
rrs1473192r.1347a>g0.931
rrs1473202r.1357c>t0.924
rrs1473205r.1360t>c0.926
rrs1473226r.1381c>t0.931
rrs1473288r.1443c>t0.333
rrs1473290r.1445c>t0.333
rrs1473291r.1446g>t0.385
rrs1473327r.1482a>g0.381
rrs1473328r.1483c>t0.481
rrs1473352r.1507c>t0.952
rrl1473384c.-274A>T0.649
rrl1473437c.-221T>C0.308
rrl1473449c.-209G>A0.250
rrl1473454c.-204A>G0.214
rrl1473569c.-89A>T0.462
rrl1473571c.-87C>T0.462
rrl1473659r.2t>c0.818
rrl1473668r.11c>t0.833
rrl1473676r.19g>a0.833
rrl1473765r.108a>g0.308
rrl1473770r.113t>g0.308
rrl1473851r.194g>c0.556
rrl1473862r.205c>a0.571
rrl1473869r.212c>t0.571
rrl1473871r.214t>g0.571
rrl1473876r.219g>a0.900
rrl1473877r.220g>a0.600
rrl1473887r.230t>a0.885
rrl1473888r.231t>a0.923
rrl1473898r.241c>t0.692
rrl1473899r.242a>t0.240
rrl1473905r.248t>c0.692
rrl1473918r.261c>t0.259
rrl1474061r.404t>c0.846
rrl1474089r.432c>t0.636
rrl1474093r.436g>a0.636
rrl1474100r.443c>t0.636
rrl1474103r.446a>t0.636
rrl1474110r.453a>g0.636
rrl1474111r.454t>c0.636
rrl1474130r.473c>t0.625
rrl1474140r.483c>t0.643
rrl1474151r.494c>t0.615
rrl1474181r.524c>t0.722
rrl1474218r.561t>a0.916
rrl1474228r.571t>a0.913
rrl1474232r.575c>g0.913
rrl1474239r.582g>c0.915
rrl1474249r.592g>a0.955
rrl1474252r.595t>a0.908
rrl1474291r.634tttcctctccggagga>t0.538
rrl1474308r.651g>t0.600
rrl1474310r.653t>g0.600
rrl1474330r.673a>t0.864
rrl1474338r.681g>a0.368
rrl1474341r.684t>g0.368
rrl1474348r.691c>t0.222
rrl1474381r.724t>g0.286
rrl1474433r.776g>t0.400
rrl1474447r.790g>a0.417
rrl1474552r.895c>t0.478
rrl1474555r.898t>g0.478
rrl1474562r.905g>c0.520
rrl1474565r.908t>a0.542
rrl1474570r.913g>t0.538
rrl1474571r.914g>t0.613
rrl1474578r.921a>g0.700
rrl1474584r.927c>g0.810
rrl1474586r.929t>a0.836
rrl1474747r.1090c>a0.333
rrl1474753r.1096a>g0.625
rrl1474758r.1101g>a0.773
rrl1474779r.1122g>a0.960
rrl1474780r.1123c>t0.960
rrl1474782r.1125g>a0.958
rrl1474790r.1133c>t0.968
rrl1474798r.1141c>t0.963
rrl1474804r.1147c>t0.968
rrl1474823r.1166c>g0.975
rrl1474827r.1170c>t0.972
rrl1474844r.1187g>t0.972
rrl1474866r.1209c>a0.967
rrl1474869r.1212g>t0.967
rrl1474896r.1239a>g0.963
rrl1474902r.1245t>c0.957
rrl1474904r.1247g>c0.961
rrl1474913r.1256t>a0.959
rrl1474920r.1263g>a0.957
rrl1474928r.1271c>a0.500
rrl1474931r.1274g>a0.708
rrl1474938r.1281g>a0.667
rrl1474945r.1288c>t0.333
rrl1474946r.1289c>t0.400
rrl1475034r.1377g>a0.471
rrl1475046r.1389a>c0.965
rrl1475049r.1392c>t0.965
rrl1475052r.1395g>a0.965
rrl1475061r.1404c>a1.000
rrl1475065r.1408g>a0.966
rrl1475076r.1419c>t0.970
rrl1475081r.1424c>t0.973
rrl1475092r.1435a>c0.948
rrl1475094r.1437c>t0.948
rrl1475099r.1442g>a0.948
rrl1475106r.1449g>a0.932
rrl1475108r.1451c>g0.924
rrl1475109r.1452c>a0.940
rrl1475114r.1457c>t0.932
rrl1475115r.1458a>c0.924
rrl1475120r.1463g>a0.929
rrl1475122r.1465c>t0.934
rrl1475129r.1472g>a0.961
rrl1475154r.1497c>a0.966
rrl1475167r.1510t>a0.955
rrl1475175r.1518g>a0.940
rrl1475188r.1531c>t0.917
rrl1475313r.1656g>a0.786
rrl1475315r.1658a>t0.786
rrl1475355r.1698c>t0.778
rrl1475369r.1712g>t0.824
rrl1475404r.1747a>g0.643
rrl1475405r.1748a>t0.688
rrl1475419r.1762c>t0.647
rrl1475429r.1772g>a0.588
rrl1475453r.1796t>a0.556
rrl1475476r.1819g>c0.190
rrl1475480r.1823a>g0.500
rrl1475483r.1826c>t0.500
rrl1475487r.1830c>t0.500
rrl1475498r.1841c>g0.188
rrl1475505r.1848g>a0.353
rrl1475526r.1869c>a0.455
rrl1475550r.1893a>c0.333
rrl1475552r.1895g>c0.600
rrl1475574r.1917c>a0.977
rrl1475657r.2000a>g0.300
rrl1475659r.2002g>a0.500
rrl1475672r.2015c>g0.965
rrl1475673r.2016t>c0.965
rrl1475687r.2030c>t0.963
rrl1475696r.2039t>c0.966
rrl1475703r.2046a>g0.970
rrl1475707r.2050t>a0.971
rrl1475716r.2059a>g0.966
rrl1475747r.2090a>g0.676
rrl1475803r.2146t>c0.960
rrl1475804r.2147g>c0.960
rrl1475816r.2159c>g0.961
rrl1475817r.2160a>g0.961
rrl1475843r.2186g>a0.962
rrl1475849r.2192g>a0.957
rrl1475853r.2196c>t0.952
rrl1475858r.2201t>c0.951
rrl1475999r.2342g>t0.400
rrl1476030r.2373a>g0.364
rrl1476032r.2375c>t0.364
rrl1476033r.2376t>c0.400
rrl1476034r.2377c>g0.400
rrl1476100r.2443a>t0.417
rrl1476113r.2456t>a0.976
rrl1476115r.2458t>a0.988
rrl1476122r.2465a>c0.976
rrl1476126r.2469c>t0.972
rrl1476128r.2471t>a0.976
rrl1476135r.2478t>c0.981
rrl1476141r.2484a>g0.985
rrl1476153r.2496t>c0.989
rrl1476164r.2507a>g0.987
rrl1476165r.2508t>a0.983
rrl1476194r.2537a>g0.667
rrl1476195r.2538c>a0.643
rrl1476196r.2539c>a0.643
rrl1476200r.2543a>t0.692
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rrl1476204r.2547c>a0.692
rrl1476210r.2553g>t0.692
rrl1476211r.2554g>t0.692
rrl1476212r.2555t>c0.692
rrl1476214r.2557g>t0.308
rrl1476215r.2558c>t0.308
rrl1476221r.2564t>c0.937
rrl1476225r.2568t>g0.942
rrl1476229r.2572c>a0.943
rrl1476251r.2594t>c1.000
rrl1476260r.2603a>g0.985
rrl1476280r.2623a>c0.985
rrl1476293r.2636c>t0.971
rrl1476294r.2637a>g0.957
rrl1476295r.2638c>g0.957
rrl1476296r.2639c>t0.957
rrl1476297r.2640c>g0.944
rrl1476302r.2645g>a0.942
rrl1476311r.2654g>c0.943
rrl1476312r.2655t>c0.943
rrl1476313r.2656g>a0.943
rrl1476332r.2675g>c0.966
rrl1476338r.2681c>t0.966
rrl1476353r.2696g>t0.981
rrl1476358r.2701t>c0.980
rrl1476372r.2715t>c0.986
rrl1476382r.2725a>g0.948
rrl1476383r.2726t>a0.986
rrl1476408r.2751g>a0.988
rrl1476425r.2768g>a0.988
rrl1476428r.2771c>t0.984
rrl1476466r.2809c>t0.972
rrl1476481r.2824t>c0.968
rrl1476506r.2849t>c0.963
rrl1476512r.2855c>t0.894
rrl1476514r.2857c>t0.906
rrl1476519r.2862c>g0.902
rrl1476523r.2866t>c0.877
rrl1476524r.2867c>a0.855
rrl1476525r.2868a>g0.855
rrl1476530r.2873c>t0.877
rrl1476536r.2879g>a0.866
rrl1476537r.2880a>g0.877
rrl1476538r.2881a>g0.877
rrl1476540r.2883c>g0.890
rrl1476547r.2890c>t0.965
rrl1476567r.2910c>t0.963
rrl1476573r.2916a>t0.959
rrl1476577r.2920t>g0.959
rrl1476584r.2927c>t0.954
rrl1476594r.2937c>t0.946
rrl1476603r.2946g>a0.906
rrl1476607r.2950c>t0.897
rrl1476608r.2951c>a0.897
rrl1476614r.2957a>g0.895
rrl1476621r.2964c>a0.894
rrl1476624r.2967t>a0.894
rrl1476628r.2971t>c0.968
rrl1476629r.2972c>a0.894
rrl1476630r.2973a>g0.896
rrl1476637r.2980c>g0.957
rrl1476657r.3000g>t0.375
rrl1476716r.3059a>c0.700
rrl1476750r.3093t>c0.700
rrl1476755r.3098g>a0.700
rrl1476759r.3102t>c0.700
rrl1476770r.3113t>c0.700
rrl1476771r.3114g>a0.700
fabG11673475c.36A>C0.700
fabG11673499c.60T>C0.727
fabG11673505c.66A>T0.762
fabG11673517c.78G>C0.765
fabG11673524c.85C>T0.765
fabG11673535c.96A>G0.812
fabG11673565c.126G>C0.867
fabG11673580c.141T>C0.750
fabG11673589c.150A>G0.692
fabG11673595c.156A>C0.636
fabG11673596p.Lys53Glu0.636
fabG11673604c.165G>C0.636
fabG11673607c.168T>C0.636
fabG11673615p.Glu59Val0.700
fabG11673646c.207T>C0.636
fabG11673657p.Thr73Lys0.667
fabG11673660p.Ala74Glu0.615
fabG11673664c.225A>C0.615
fabG11673667c.228A>G0.615
fabG11673679c.240T>C0.562
fabG11673697c.258G>C0.650
fabG11673710p.Leu91Ile0.562
fabG11673716p.Ala93Lys0.500
fabG11673724c.285A>C0.474
fabG11673730c.291C>G0.474
fabG11673733p.Met98Ile0.500
fabG11673745c.306G>A0.500
fabG11673748c.309A>G0.500
fabG11673749p.Lys104Arg0.500
fabG11673758p.Lys107Glu0.545
fabG11673784c.345G>C0.571
fabG11673793c.354G>A0.591
fabG11673799c.360T>C0.550
fabG11673802c.363A>G0.526
fabG11673808c.369A>G0.526
fabG11673829p.Asn130Lys0.375
fabG11673830p.Lys131Arg0.375
fabG11673838c.399T>C0.400
fabG11673841c.402A>G0.400
fabG11673844p.Met135Ile0.400
fabG11673847c.408A>C0.400
fabG11673853c.414A>C0.400
fabG11673856c.417T>G0.400
fabG11673865c.426C>G0.500
fabG11673870p.Ser144Met0.533
fabG11673877c.438C>T0.684
fabG11673901c.462A>C0.667
fabG11673904c.465C>G0.667
fabG11673905p.Ser156Ala0.667
fabG11673916c.477A>C0.625
fabG11673917p.Val160Leu0.625
fabG11673922c.483T>C0.625
fabG11673925c.486C>G0.625
fabG11673941p.Ala168Ser0.647
fabG11673946c.507C>G0.647
fabG11673955c.516G>C0.625
fabG11673961c.522A>C0.462
fabG11673962p.Asn175Gly0.500
fabG11673973c.534G>C0.545
fabG11673976c.537T>C0.545
fabG11673982c.543G>T0.571
fabG11673988c.549G>C0.571
fabG11674006p.Asp189Glu0.562
fabG11674015c.576C>G0.538
fabG11674021c.582G>C0.455
fabG11674078c.639C>G0.467
fabG11674079p.Pro214Ala0.467
fabG11674083p.Ala215Glu0.467
fabG11674096c.657G>A0.500
fabG11674098p.Val220Ala0.500
fabG11674114c.675T>G0.529
fabG11674132c.693T>C0.500
fabG11674136p.Ser233Ala0.533
fabG11674141c.702T>C0.533
fabG11674150c.711C>T0.500
fabG11674153c.714G>C0.467
fabG11674171c.732T>C0.375
inhA1674205p.Thr2Ala0.333
inhA1674216c.15G>C0.353
inhA1674231c.30T>C0.533
inhA1674237c.36T>C0.533
inhA1674239p.Ser13Thr0.533
inhA1674243c.42A>G0.562
inhA1674258c.57G>C0.562
inhA1674279c.78A>C0.200
inhA1674280p.Arg27Lys0.200
inhA1674285c.84A>C0.200
inhA1674288c.87C>T0.200
inhA1674315c.114C>G0.316
inhA1674321c.120G>A0.300
inhA1674336c.135G>A0.318
inhA1674342c.141T>C0.292
inhA1674352p.Thr51Ala0.280
inhA1674357c.156C>T0.304
inhA1674367p.Ala56Gln0.273
inhA1674382p.Leu61Ile0.261
inhA1674399c.198A>G0.240
inhA1674463p.Leu88Ile0.526
inhA1674471c.270G>C0.591
inhA1674480c.279T>C0.542
inhA1674489c.288G>T0.565
inhA1674507c.306G>A0.619
inhA1674534c.333G>C0.471
inhA1674537c.336C>A0.444
inhA1674540c.339C>T0.444
inhA1674542p.Ala114Glu0.444
inhA1674549c.348G>C0.429
inhA1674555c.354G>A0.455
inhA1674561c.360C>T0.476
inhA1674582c.381T>C0.353
inhA1674585c.384T>C0.353
inhA1674588c.387G>A0.353
inhA1674589p.Met130Leu0.353
inhA1674601p.Leu134Val0.316
inhA1674618c.417C>T0.250
inhA1674624c.423A>T0.211
inhA1674627c.426T>C0.222
inhA1674655c.454A>T0.158
inhA1674703c.502T>C0.263
inhA1674717c.516C>T0.278
inhA1674718c.517A>C0.278
inhA1674729c.528G>A0.450
inhA1674745p.Tyr182Ala0.409
inhA1674756c.555T>C0.476
inhA1674759c.558G>C0.476
inhA1674765c.564C>T0.500
inhA1674774c.573A>C0.474
inhA1674777c.576C>A0.500
inhA1674780c.579T>G0.476
inhA1674792c.591G>C0.500
inhA1674801c.600T>C0.524
inhA1674820c.619C>T0.577
inhA1674828c.627G>A0.571
inhA1674846p.Ile215Met0.500
inhA1674870c.669T>C0.577
inhA1674876c.675C>G0.600
inhA1674879c.678T>C0.600
inhA1674888c.687C>T0.636
inhA1674904p.Ala235Pro0.565
inhA1674909c.708G>C0.565
inhA1674915c.714C>G0.615
inhA1674939c.738G>A0.640
inhA1674942c.741T>C0.615
inhA1674966c.765T>C0.545
inhA1674967p.Asp256Thr0.524
inhA1674993c.792G>C0.417
inhA1674994p.His265Ser0.385
inhA1675006c.805C>T0.286
rpsA1833532c.-10A>C0.222
rpsA1833568c.27G>C0.318
rpsA1833589c.48A>T0.320
rpsA1833595c.54T>C0.348
rpsA1833613c.72C>A0.381
rpsA1833619c.78A>C0.364
rpsA1833661c.120A>G0.571
rpsA1833667c.126C>G0.600
rpsA1833703c.162C>T0.667
rpsA1833724c.183C>G0.562
rpsA1833727c.186G>C0.500
rpsA1833745c.204G>C0.611
rpsA1833760c.219C>T0.611
rpsA1833790c.249T>C0.625
rpsA1833793c.252C>T0.625
rpsA1833802c.261A>G0.560
rpsA1833808c.267G>C0.480
rpsA1833811c.270G>T0.480
rpsA1833832c.291G>A0.480
rpsA1833838c.297G>C0.462
rpsA1833841c.300C>G0.480
rpsA1833847c.306C>G0.409
rpsA1833856c.315A>G0.409
rpsA1833859c.318C>T0.375
rpsA1833874c.333T>C0.294
rpsA1833895c.354G>C0.294
rpsA1833928c.387G>C0.364
rpsA1833949c.408T>C0.286
rpsA1833964c.423C>T0.312
rpsA1833970c.429G>A0.333
rpsA1833979c.438T>C0.421
rpsA1834000c.459G>C0.421
rpsA1834015c.474G>C0.529
rpsA1834021c.480C>T0.529
rpsA1834102c.561T>C0.562
rpsA1834105c.564C>T0.533
rpsA1834150c.609G>C0.273
rpsA1834153c.612T>C0.300
rpsA1834154p.Asn205Gln0.273
rpsA1834157c.616T>C0.273
rpsA1834162c.621A>G0.300
rpsA1834165c.624A>G0.364
rpsA1834177c.636A>C0.533
rpsA1834186c.645C>G0.625
rpsA1834189c.648G>C0.625
rpsA1834195c.654G>C0.688
rpsA1834222c.681T>C0.542
rpsA1834225c.684C>G0.684
rpsA1834231c.690T>G0.700
rpsA1834249c.708T>C0.696
rpsA1834261c.720A>G0.773
rpsA1834264c.723G>C0.773
rpsA1834297c.756C>T0.696
rpsA1834303c.762T>G0.600
rpsA1834306c.765T>C0.625
rpsA1834336c.795C>G0.579
rpsA1834348c.807T>C0.571
rpsA1834357c.816T>C0.500
rpsA1834366c.825A>G0.476
rpsA1834375c.834G>A0.429
rpsA1834396c.855G>T0.500
rpsA1834411c.870T>C0.368
rpsA1834423c.882G>T0.389
rpsA1834451c.910T>C0.381
rpsA1834456c.915T>G0.300
rpsA1834465c.924T>C0.294
rpsA1834468c.927A>G0.278
rpsA1834477c.936C>T0.278
rpsA1834489c.948T>C0.333
rpsA1834519c.978G>C0.200
rpsA1834546c.1005T>C0.462
rpsA1834555c.1014T>G0.538
rpsA1834603c.1062G>A0.750
rpsA1834609c.1068T>C0.600
rpsA1834612c.1071G>A0.688
rpsA1834633c.1092A>G0.706
rpsA1834639c.1098T>C0.696
rpsA1834654c.1113G>A0.643
rpsA1834690c.1149T>C0.583
rpsA1834699p.Glu386Asp0.615
rpsA1834732c.1191T>C0.433
rpsA1834747c.1206A>G0.267
rpsA1834751p.Leu404Met0.267
rpsA1834756c.1215G>A0.308
rpsA1834759c.1218A>C0.286
rpsA1834765p.Glu408Asp0.235
rpsA1834766p.Lys409Ala0.235
rpsA1834775p.Ala412Gln0.235
rpsA1834780c.1239A>G0.250
rpsA1834789c.1248T>C0.567
rpsA1834792c.1251G>C0.567
rpsA1834813c.1272G>T0.633
rpsA1834852c.1311C>G0.562
rpsA1834858c.1317G>A0.567
rpsA1834864c.1323T>C0.567
rpsA1834869p.Arg443His0.548
rpsA1834916p.Thr459Pro1.000
rpsA1834945c.1404C>A0.269
rpsA1834954c.1413G>C0.259
rpsA1834957c.1416C>G0.269
rpsA1834969c.1428A>G0.269
tlyA1917940p.Val1Met0.407
tlyA1917945c.6A>G0.407
tlyA1917948c.9A>G0.423
tlyA1917951c.12T>C0.423
tlyA1917957c.18C>T0.500
tlyA1917972c.33A>G1.000
tlyA1917981c.42G>C0.500
tlyA1917984c.45C>T0.520
tlyA1917985c.46C>T0.520
tlyA1917990c.51G>A0.500
tlyA1917996c.57A>C0.565
tlyA1917999c.60T>C0.542
tlyA1918002c.63A>G0.542
tlyA1918008c.69C>G0.565
tlyA1918011c.72G>C0.565
tlyA1918029c.90C>G0.600
tlyA1918035c.96G>C0.600
tlyA1918036p.Arg33Ser0.600
tlyA1918047c.108G>C0.600
tlyA1918048p.Leu37Met0.600
tlyA1918281c.342A>C0.800
tlyA1918291c.352C>T0.200
tlyA1918296c.357G>C0.207
tlyA1918377c.438T>A0.344
tlyA1918380c.441C>T0.355
tlyA1918390p.Val151Ile0.379
tlyA1918395c.456G>C0.407
tlyA1918410c.471C>T0.423
tlyA1918420p.Ala161Ser0.409
tlyA1918442p.Val168Ala0.409
tlyA1918446c.507A>T0.409
tlyA1918452c.513T>G0.381
tlyA1918454p.Ser172Trp0.381
tlyA1918457p.Arg173Pro0.364
tlyA1918460p.Asp174Gly0.391
tlyA1918464c.525C>G0.375
tlyA1918476c.537A>C0.452
tlyA1918477p.Leu180Met0.452
tlyA1918623c.684C>T0.259
tlyA1918635c.696C>A0.259
tlyA1918638c.699A>G0.259
tlyA1918647c.708T>C0.259
tlyA1918653c.714G>A0.259
tlyA1918666c.727T>C0.259
katG2154724p.Arg463Leu1.000
katG2154858c.1254T>G0.583
katG2154866p.Ile416Leu0.615
katG2154892p.Glu407Ala0.571
katG2155017c.1095C>G0.643
katG2155026c.1086G>C0.737
katG2155047c.1065G>C0.667
katG2155054p.Tyr353Phe0.636
katG2155056c.1056T>C0.667
katG2155062c.1050A>G0.680
katG2155068c.1044A>C0.708
katG2155071c.1041A>C0.708
katG2155080c.1032C>G0.708
katG2155083c.1029C>G0.708
katG2155086c.1026C>T0.720
katG2155119c.993A>G0.667
katG2155131c.981T>C0.611
katG2155134c.978C>G0.647
katG2155140c.972G>C0.647
katG2155145p.Asn323Pro0.647
katG2155152c.960T>C0.611
katG2155155c.957G>C0.611
katG2155185c.927A>G0.591
katG2155189p.Thr308Lys0.591
katG2155191c.921T>G0.591
katG2155203c.909C>G0.619
katG2155221c.891G>C0.200
katG2155320c.792C>G0.522
katG2155323c.789C>G0.522
katG2155326c.786T>C0.500
katG2155329c.783T>C0.500
katG2155333p.Val260Glu0.500
katG2155344c.768G>C0.522
katG2155350c.762G>C0.522
katG2155355p.Arg253Gly0.462
katG2155356c.756A>G0.480
katG2155534p.Pro193His1.000
katG2155566c.546C>G0.333
katG2155572c.540C>T0.304
katG2155581c.531G>T0.304
katG2155587c.525C>G0.391
katG2155590c.522T>C0.417
katG2155614c.498A>C0.261
katG2155619p.Ile165Leu0.261
katG2155626c.486C>G0.261
katG2155632c.480T>C0.261
katG2155637p.Leu159Ile0.261
katG2155641p.Lys157Asn0.273
katG2155656c.456C>T0.375
katG2155661p.Val151Ile0.375
katG2155680c.432C>A0.350
katG2155691c.421A>G0.353
katG2155695c.417G>C0.400
katG2155716c.396A>G0.421
katG2155728c.384C>G0.500
kasA2518162c.48G>A0.500
kasA2518169p.Val19Leu0.455
kasA2518172p.Thr20Ala0.455
kasA2518190p.Ser26Ala0.417
kasA2518199p.Ile29Val0.500
kasA2518219c.105T>C0.636
kasA2518220c.106C>T0.636
kasA2518245p.His44Arg0.652
kasA2518248p.Ala45Val0.682
kasA2518261p.Glu49Asp0.800
kasA2518273c.159G>A0.800
kasA2518279p.Asp55Glu0.625
kasA2518282c.168A>G0.625
kasA2518283p.Ala57Pro0.625
kasA2518289p.Lys59Gln0.588
kasA2518297c.183C>T0.550
kasA2518300c.186T>A0.524
kasA2518312p.Asp66Glu0.550
kasA2518316p.Val68Ile0.550
kasA2518321c.207C>T0.524
kasA2518323p.Ser70Asn0.524
kasA2518336c.222A>G0.267
kasA2518339c.225C>G0.267
kasA2518342c.228C>T0.267
kasA2518343p.Met77Leu0.267
kasA2518351c.237C>G0.250
kasA2518363c.249C>T0.214
kasA2518439p.Ala109Ser0.400
kasA2518447c.333T>C0.429
kasA2518450c.336C>T0.414
kasA2518459c.345T>C0.438
kasA2518462c.348A>G0.441
kasA2518468c.354A>C0.500
kasA2518475c.361A>C0.500
kasA2518480c.366T>C0.516
kasA2518492c.378C>T0.471
kasA2518504c.390T>C0.417
kasA2518506p.Ala131Glu0.417
kasA2518519c.405G>C0.389
kasA2518528c.414C>G0.417
kasA2518534c.420G>C0.432
kasA2518561c.447T>C0.433
kasA2518567c.453G>C0.227
kasA2518570c.456G>C0.208
kasA2518573c.459G>C0.208
kasA2518574p.Ile154Val0.208
kasA2518582c.468G>C0.192
kasA2518583p.Gln157Glu0.192
kasA2518594c.480C>T0.324
kasA2518597c.483C>G0.364
kasA2518606c.492G>C0.361
kasA2518609p.Met165Ile0.378
kasA2518636c.522C>A0.385
kasA2518639c.525G>C0.385
kasA2518642c.528A>G0.385
kasA2518645c.531G>C0.405
kasA2518651c.537C>G0.436
kasA2518657c.543G>C0.450
kasA2518663c.549T>C0.475
kasA2518672c.558G>C0.487
kasA2518678c.564C>T0.459
kasA2518681c.567C>T0.421
kasA2518684c.570C>G0.421
kasA2518687p.Asp191Glu0.421
kasA2518693c.579C>G0.476
kasA2518702c.588C>T0.474
kasA2518711c.597A>G0.429
kasA2518714c.600A>C0.441
kasA2518717c.603C>G0.455
kasA2518723c.609G>A0.485
kasA2518735c.621C>T0.500
kasA2518747c.633C>G0.514
kasA2518768c.654C>G0.536
kasA2518783c.669T>C0.538
kasA2518789c.675G>C0.538
kasA2518795c.681C>A0.538
kasA2518798c.684G>C0.538
kasA2518825c.711T>C0.406
kasA2518840c.726C>G0.357
kasA2518843c.729T>G0.417
kasA2518846c.732G>C0.357
kasA2518853p.Leu247Val0.148
kasA2518864c.750G>C0.500
kasA2518879c.765A>G0.435
kasA2518885c.771T>C0.308
kasA2518894c.780G>A0.286
kasA2518898c.784T>C0.300
kasA2518906c.792A>G0.235
kasA2518907c.793T>C0.235
kasA2518910p.Leu266Met0.211
kasA2518915c.801T>C0.211
kasA2518930c.816G>C0.304
kasA2518939c.825T>C0.273
kasA2518942c.828T>C0.273
kasA2519029c.915C>T0.259
kasA2519038c.924C>A0.267
kasA2519044c.930G>A0.333
kasA2519056c.942G>A0.344
kasA2519062c.948T>G0.393
kasA2519072p.Ala320Thr0.375
kasA2519077c.963G>A0.435
kasA2519095c.981C>G0.444
kasA2519098c.984C>T0.444
kasA2519104c.990T>A0.421
kasA2519107c.993T>C0.421
kasA2519110p.Asp332Glu0.400
kasA2519112p.Gln333Arg0.421
kasA2519119c.1005G>C0.458
kasA2519134c.1020G>A0.400
kasA2519137c.1023T>G0.400
kasA2519140c.1026G>A0.400
kasA2519146c.1032C>A0.450
kasA2519152c.1038G>C0.476
kasA2519161c.1047G>A0.500
kasA2519167c.1053T>G0.609
kasA2519194c.1080G>T0.579
kasA2519195p.Thr361Ser0.579
kasA2519203c.1089C>G0.579
kasA2519206c.1092C>T0.579
kasA2519209c.1095C>T0.619
kasA2519215c.1101C>T0.625
kasA2519227c.1113G>C0.652
kasA2519236c.1122G>A0.636
kasA2519239c.1125A>C0.636
kasA2519257c.1143C>T0.400
kasA2519258c.1144C>T0.400
kasA2519263c.1149C>T0.400
kasA2519269c.1155C>T0.400
kasA2519272c.1158C>G0.400
kasA2519273p.Gly387Ser0.400
kasA2519278c.1164A>G0.400
kasA2519281c.1167G>T0.400
kasA2519287c.1173T>C0.400
kasA2519293c.1179T>C0.400
kasA2519295p.Tyr394Phe0.286
kasA2519305c.1191A>G0.762
kasA2519306p.Val398Ile0.762
kasA2519317c.1203G>A0.583
kasA2519338c.1224T>C0.609
kasA2519344c.1230G>C0.609
kasA2519347c.1233T>C0.591
ahpC2726591c.399C>G0.524
ahpC2726600c.408T>C0.560
ahpC2726627c.435G>A0.609
ahpC2726645c.453C>G0.600
ahpC2726654c.462G>C0.600
ahpC2726657c.465A>G0.600
ahpC2726660c.468C>T0.591
ahpC2726669c.477T>C0.474
ahpC2726675c.483A>G0.474
ahpC2726681c.489A>G0.474
ahpC2726687c.495C>G0.412
ahpC2726690c.498C>T0.412
ahpC2726693c.501C>T0.353
ahpC2726696c.504C>G0.333
ahpC2726699c.507G>A0.375
ahpC2726717c.525A>C0.389
folC2746813c.786T>C0.263
folC2746819c.780A>G0.263
folC2747011c.588C>T0.150
folC2747023c.576G>C0.500
folC2747032c.567T>C0.652
folC2747047c.552G>A0.600
folC2747053c.546G>A0.654
folC2747062c.537T>A0.704
folC2747086c.513T>G0.706
folC2747089c.510C>G0.706
folC2747092p.Asp169Glu0.694
folC2747098c.501G>C0.703
folC2747107c.492C>G0.694
folC2747110c.489A>G0.656
folC2747113c.486G>C0.636
folC2747133p.Thr156Val0.618
folC2747134c.465G>C0.618
folC2747137c.462C>G0.600
folC2747161c.438G>A0.576
folC2747215c.384C>T0.176
folC2747233c.366C>G0.176
folC2747242c.357C>T0.167
folC2747248c.351C>T0.176
folC2747263c.336G>T0.188
folC2747274p.Ser109Ala0.188
folC2747275c.324A>G0.188
folC2747281c.318T>C0.176
folC2747289p.Pro104Ala0.167
folC2747290c.309T>C0.167
folC2747314c.285T>G0.222
folC2747317c.282G>T0.222
folC2747323c.276G>A0.235
folC2747335c.264C>T0.200
folC2747509c.90A>G0.222
folC2747515c.84C>T0.222
folC2747533c.66G>A0.190
ribD2986931c.93T>C0.231
ribD2986936p.Asp33Ala0.231
ribD2987340p.Asp168Tyr0.250
thyX3067319c.627C>A0.179
thyX3067325c.621T>C0.212
thyX3067337c.609G>A0.242
thyX3067340c.606C>T0.242
thyX3067349c.597C>G0.229
thyX3067355c.591T>C0.229
thyX3067358c.588G>A0.229
thyX3067379c.567G>A0.281
thyX3067394c.552C>G0.357
thyX3067400c.546G>C0.357
thyX3067406c.540T>C0.357
thyX3067418c.528G>C0.367
thyX3067427c.519C>G0.367
thyX3067430c.516G>A0.345
thyX3067439c.507T>C0.286
thyX3067442c.504G>T0.286
thyX3067445c.501G>C0.296
thyX3067448c.498C>T0.296
thyX3067454c.492G>A0.357
thyX3067457c.489G>C0.357
thyX3067465p.Ile161Val0.379
thyX3067498c.448G>A0.355
thyX3067634c.312G>C0.407
thyX3067652c.294A>G0.478
thyX3067661c.285G>T0.520
thyX3067676c.270G>C0.429
thyX3067680p.Cys89Leu0.400
thyX3067685c.261T>C0.387
thyX3067693p.Ile85Val0.400
thyX3067694c.252C>G0.400
thyX3067718c.228G>C0.500
thyX3067727c.219T>G0.528
thyX3067739c.207A>G0.571
thyX3067742c.204T>G0.559
thyX3067762p.Arg62Lys0.529
thyX3067765p.Leu61Ile0.529
thyX3067781c.165G>C0.537
thyX3067793c.153A>G0.436
thyX3067802c.144G>C0.395
thyX3067814c.132A>G0.325
thyX3067817c.129G>A0.325
thyX3067841c.105C>A0.306
thyX3067869p.Thr26Ser0.160
thyX3067877c.69C>G0.217
thyX3067886c.60T>C0.208
thyX3067889c.57G>C0.208
thyX3067894c.52A>G0.227
thyX3067898p.Asp16Glu0.250
thyX3067901c.45G>C0.250
thyX3067935p.Thr4Ile0.261
thyX3067937c.9C>T0.261
thyX3067952c.-7G>A0.286
thyA3073686c.786C>A0.250
thyA3073692c.780T>G0.250
thyA3073695c.777A>C0.267
thyA3073710c.762A>G0.353
thyA3073722c.750G>A0.353
thyA3073728c.744C>G0.400
thyA3073731c.741A>G0.429
thyA3073736p.Ile246Val0.467
thyA3073743c.729A>G0.444
thyA3073752p.Glu240Asp0.471
thyA3073761c.711T>C0.533
thyA3073772p.Asp234His0.538
thyA3073776c.696T>A0.538
thyA3073781p.Leu231Phe0.438
thyA3073782c.690T>G0.438
thyA3073787p.Lys229Glu0.467
thyA3073794c.678T>C0.562
thyA3073820p.Leu218Ile0.412
thyA3073824c.648T>G0.412
thyA3073827c.645T>C0.412
thyA3073830p.Glu214Asp0.467
thyA3073836c.636G>A0.467
thyA3073839c.633A>G0.500
thyA3073854c.618G>A0.556
thyA3073863c.609A>G0.500
thyA3073889p.Ser195Asp0.500
thyA3073892c.580A>G0.500
thyA3073905c.567G>C0.571
thyA3073925c.547A>G0.571
thyA3073929c.543A>G0.643
thyA3073944c.528G>A0.688
thyA3073953c.519A>G0.688
thyA3073956c.516C>G0.688
thyA3073959c.513A>G0.688
thyA3073968c.504G>C0.786
thyA3073977c.495T>C0.733
thyA3073989c.483A>G0.765
thyA3074001c.471G>C0.750
thyA3074004c.468A>G0.762
thyA3074037c.435G>C0.700
thyA3074053p.Arg140Gln0.667
thyA3074057p.Glu139Pro0.667
thyA3074070c.402G>A0.632
thyA3074076c.396G>C0.611
thyA3074085c.387G>A0.625
thyA3074089p.Ile128Asn0.571
thyA3074244c.228T>G0.800
thyA3074250c.222C>T0.824
thyA3074256c.216C>T0.778
thyA3074267p.Ile69Val0.722
thyA3074268c.204A>G0.722
thyA3074274c.198A>G0.737
thyA3074280c.192G>A0.700
thyA3074297c.175G>A0.611
thyA3074301c.171G>A0.500
thyA3074305p.Ala56Val0.500
thyA3074307c.165T>C0.583
thyA3074313c.159T>C0.538
thyA3074316p.Phe52Leu0.500
thyA3074322c.150G>C0.500
thyA3074325c.147T>C0.562
thyA3074334c.138A>G0.609
thyA3074337c.135G>C0.609
thyA3074360c.112A>G0.632
thyA3074361c.111A>G0.632
thyA3074364c.108A>G0.632
thyA3074372p.Met34Leu0.556
thyA3074373c.99C>T0.526
ald3087629c.810C>T0.400
ald3087638c.819C>T0.400
ald3087641c.822T>C0.400
ald3087647c.828A>G0.400
ald3087649p.Gly277Asp0.400
ald3087653c.834A>G0.400
ald3087659c.840G>C0.462
ald3087672p.His285Asp0.500
ald3087686c.867C>G0.500
ald3087692c.873C>T0.500
ald3087699p.Leu294Met0.538
ald3087726p.Ala303Ser0.462
ald3087729p.Ser304Ala0.462
ald3087734c.915G>T0.462
ald3087743c.924G>C0.571
ald3087761c.942C>G0.533
ald3087767c.948G>C0.462
ald3087770c.951G>C0.429
fbiA3640167c.-376G>A0.200
fbiA3640347c.-196A>G0.750
fbiA3640365c.-178C>G0.700
fbiA3640554c.12C>T0.200
fbiA3640562p.Ala7Val0.176
fbiA3640566c.24T>C0.188
fbiA3640584c.42C>G0.176
fbiA3640989c.447T>C0.438
fbiA3640998c.456C>G0.444
fbiA3641004c.462A>G0.444
fbiA3641016c.474C>T0.273
fbiA3641019c.477G>C0.273
fbiA3641021p.Val160Ala0.273
fbiA3641028p.Glu162Asp0.333
fbiA3641035p.Lys165Arg0.375
fbiA3641046c.504T>C0.524
fbiA3641049c.507T>C0.524
fbiA3641070c.528C>T0.526
fbiA3641073c.531T>A0.529
fbiA3641077p.Gln179Lys0.529
fbiA3641088c.546G>C0.529
fbiA3641184c.642T>G0.389
fbiA3641190c.648G>A0.389
fbiA3641196c.654C>G0.389
fbiA3641200p.Ile220Val0.389
fbiA3641208c.666C>G0.389
fbiA3641220c.678C>G0.333
fbiA3641226c.684G>T0.267
fbiA3641271c.729C>T0.286
fbiA3641288p.Glu249Gly0.357
fbiA3641292c.750G>A0.333
fbiA3641478c.936C>T0.143
fbiA3641482p.Asn314His0.136
fbiA3641493c.951T>A0.143
fbiA3641494p.Glu318Gln0.143
alr3840215c.1206A>G0.375
alr3840223c.1198T>G0.538
alr3840230c.1191A>C0.519
alr3840236c.1185T>C0.538
alr3840239c.1182C>T0.538
alr3840242c.1179G>A0.538
alr3840248c.1173G>C0.556
alr3840274p.Val383Leu0.517
alr3840275c.1146A>C0.500
alr3840287c.1134G>A0.448
alr3840382p.Met347Leu0.316
alr3840386c.1035C>T0.273
alr3840436c.985G>A0.333
alr3840437c.984C>A0.333
alr3840443c.978C>G0.333
alr3840449c.972C>G0.364
alr3840458c.963C>G0.417
alr3840469p.Val318Ile0.458
alr3840470c.951G>C0.480
alr3840476c.945T>G0.542
alr3840502p.Leu307Val0.278
alr3840504p.Asn306Thr0.278
alr3840517p.Pro302Glu0.308
alr3840518c.903C>G0.308
alr3840523p.Ile300Val0.286
alr3840527c.894T>G0.286
alr3840534p.Gly296Ala0.333
alr3840542c.879C>T0.333
alr3840548c.873C>T0.333
alr3840551c.870C>A0.333
alr3840554c.867C>G0.467
alr3840562p.Ile287Val0.467
alr3840566c.855T>C0.562
alr3840574c.847G>A0.611
alr3840578c.843A>C0.600
alr3840599c.822C>G0.611
alr3840607p.Val272Leu0.588
alr3840620c.801A>G0.455
alr3840662c.759C>G0.714
alr3840673p.Leu250Met0.667
alr3840682p.Thr247Ala0.588
alr3840944c.477A>G0.385
alr3840950c.471C>T0.375
alr3840957p.Thr155Ser0.412
alr3840965c.456C>G0.353
alr3840968c.453C>G0.353
alr3840971c.450C>T0.375
alr3840974c.447G>T0.400
alr3840980c.441C>A0.353
alr3840989c.432C>G0.429
alr3840994p.His143Asp0.478
alr3840997c.424A>G0.440
alr3841001c.420T>C0.440
alr3841013c.408G>C0.462
alr3841018p.Leu135Val0.467
alr3841033p.Val130Ile0.419
alr3841036p.Gln129Glu0.433
alr3841037c.384C>G0.433
alr3841055c.366G>C0.545
alr3841079c.342A>G0.667
alr3841088c.333G>A0.688
alr3841100c.321T>C0.667
alr3841106c.315A>G0.639
alr3841113p.Asp103Ala0.571
alr3841115c.306A>C0.571
alr3841124c.297C>T0.590
alr3841127c.294T>C0.575
alr3841148c.273G>C0.550
alr3841154c.267G>C0.579
alr3841223c.198C>T0.353
alr3841229c.192C>G0.353
alr3841232c.189C>G0.353
alr3841240p.Leu61Val0.324
alr3841244c.177C>G0.344
alr3841249p.His58Ser0.344
alr3841250c.171G>A0.344
alr3841262c.159A>C0.355
alr3841274c.147C>T0.333
alr3841652c.-232A>T0.400
alr3841654c.-234A>C0.385
alr3841662c.-242A>G0.357
alr3841663c.-243G>A0.357
panD4043867p.Gly139Arg0.619
panD4044120c.162T>C0.700
panD4044123c.159A>G0.700
panD4044126c.156A>G0.700
panD4044138c.144A>G0.769
panD4044150c.132T>C0.786
panD4044156c.126T>C0.786
panD4044159c.123G>A0.786
panD4044162c.120T>C0.812
panD4044165c.117C>T0.812
panD4044177c.105G>C1.000
panD4044180c.102G>A0.941
panD4044188c.94A>G0.938
panD4044195c.87A>G0.938
panD4044225c.57G>A0.952
panD4044233p.Cys17Gln0.947
panD4044237c.45C>G0.950
panD4044264c.18C>G0.875
embC4240153c.291G>A1.000
embC4240339c.477G>A0.364
embC4240348c.486T>C0.364
embC4240355p.Ala165Thr0.364
embC4240471c.609C>T0.280
embC4240475p.Ala205Ser0.292
embC4240489c.627A>C0.280
embC4240490p.Pro210Ala0.280
embC4240495c.633T>C0.269
embC4240512p.Ser217Thr0.333
embC4240516c.654G>C0.333
embC4240519c.657T>C0.333
embC4240525c.663C>G0.310
embC4240561c.699C>G0.379
embC4240615c.753G>C0.400
embC4240619p.Thr253Ser0.400
embC4240632p.Met257Thr0.400
embC4240642c.780G>C0.444
embC4240645c.783G>C0.474
embC4240657c.795G>C0.444
embC4240660c.798C>G0.412
embC4240671p.Thr270Ile1.000
embC4240678c.816T>C0.400
embC4240681c.819G>C0.400
embC4240685p.Thr275Ala0.400
embC4240690c.828G>C0.500
embC4240693c.831T>C0.500
embC4240698p.Ala279Gly0.455
embC4240726c.864G>C0.478
embC4240729c.867C>G0.520
embC4240747c.885C>T0.393
embC4240759c.897C>G0.440
embC4240765c.903C>G0.409
embC4240783c.921G>C0.476
embC4240789c.927T>C0.524
embC4240795c.933C>G0.450
embC4240813p.Phe317Leu0.360
embC4240819c.957A>C0.409
embC4240831c.969T>G0.450
embC4240843c.981C>T0.421
embC4240855c.993G>C0.250
embC4240859c.997C>T0.250
embC4240867c.1005T>G0.250
embC4240870c.1008T>C0.222
embC4241059c.1197G>A0.360
embC4241071c.1209C>G0.393
embC4241086c.1224G>C0.333
embC4241095c.1233C>T0.385
embC4241101c.1239G>C0.385
embC4241121p.Ser420Asn0.381
embC4241137c.1275G>C0.381
embC4241146c.1284C>G0.386
embC4241153p.Ile431Val0.333
embC4241158c.1296T>C0.340
embC4241161c.1299C>G0.326
embC4241162c.1300T>C0.326
embC4241185c.1323G>C0.357
embC4241188c.1326C>T0.325
embC4241194c.1332C>G0.297
embC4241197c.1335G>C0.297
embC4241200c.1338C>T0.297
embC4241203c.1341T>C0.297
embC4241206c.1344G>C0.306
embC4241221c.1359C>T0.154
embC4241311c.1449C>G0.269
embC4241313p.Ala484Val0.240
embC4241319p.Pro486Leu0.240
embC4241326c.1464T>C0.278
embC4241329c.1467T>C0.188
embC4241394p.Lys511Ser0.379
embC4241452c.1590G>C0.400
embC4241455c.1593C>T0.417
embC4241461c.1599C>G0.417
embC4241470c.1608C>G0.391
embC4241560c.1698C>T0.333
embC4241567p.Ile569Val0.368
embC4241572c.1710C>A0.368
embC4241578c.1716G>C0.350
embC4241584c.1722T>C0.350
embC4241587c.1725C>G0.350
embC4241593c.1731C>G0.350
embC4241611c.1749G>C0.333
embC4241614c.1752A>C0.333
embC4241623c.1761C>G0.353
embC4241641c.1779C>T0.312
embC4241644c.1782G>C0.357
embC4241648c.1786T>C0.333
embC4241656c.1794G>T0.312
embC4241665c.1803G>C0.333
embC4241668c.1806G>A0.333
embC4241671c.1809T>G0.333
embC4241791c.1929G>C0.467
embC4241797c.1935C>T0.533
embC4241809c.1947A>C0.571
embC4241818c.1956C>T0.571
embC4241881c.2019G>A1.000
embC4242112c.2250G>C0.385
embC4242121c.2259A>G0.357
embC4242127c.2265G>C0.357
embC4242128p.Leu756Met0.312
embC4242136c.2274G>A0.312
embC4242138p.Leu759Gln0.312
embC4242142p.Asp760Glu0.294
embC4242151c.2289A>C0.312
embC4242154c.2292C>G0.353
embC4242428p.Ala856Ser0.200
embC4242434p.Val858Met0.188
embC4242625c.2763T>C0.143
embC4242629p.Ala923Ser0.158
embC4242643c.2781C>T0.829
embC4242682c.2820C>G0.314
embC4242691c.2829C>T0.333
embC4242704p.Asp948Asn0.343
embC4242709c.2847C>T0.343
embC4242710p.Gln950Glu0.343
embC4242715c.2853T>C0.343
embC4242716c.2854C>T0.378
embC4242877c.3015G>A0.167
embC4242880c.3018A>G0.176
embC4242883c.3021C>G0.176
embC4242886c.3024G>A0.176
embC4242901c.3039G>C0.214
embC4242905c.3043C>A0.214
embA4243404p.Ile58Val0.250
embA4243415c.183T>C0.235
embA4243421c.189A>G0.222
embA4243427c.195G>C0.235
embA4243433c.201A>G0.211
embA4243442c.210G>C0.211
embA4243451c.219G>C0.200
embA4243457c.225C>G0.190
embA4243461p.Ser77Ala0.182
embA4243466c.234C>G0.182
embA4243475c.243G>C0.200
embA4243481c.249C>G0.158
embA4243482p.Ala84Pro0.158
embA4244372c.1140T>C0.400
embA4244381c.1149G>A0.381
embA4244390c.1158G>C0.381
embA4244933c.1701A>G0.190
embA4244936c.1704C>G0.190
embA4244951c.1719G>A0.174
embA4245023c.1791A>G0.211
embA4245026c.1794T>C0.211
embA4245029c.1797T>C0.211
embA4245032c.1800A>G0.211
embA4245038c.1806C>T0.263
embA4245041c.1809C>G0.300
embA4245056c.1824C>G0.444
embA4245060c.1828T>C0.421
embA4245063c.1831C>T0.421
embA4245078p.Trp616Val0.391
embA4245083c.1851A>C0.440
embA4245089c.1857G>C0.462
embA4245093p.Ile621Val0.500
embA4245101c.1869G>C0.500
embA4245125c.1893G>C0.591
embA4245137c.1905T>C0.722
embA4245149c.1917C>G0.722
embA4245245c.2013C>G0.667
embA4245266p.Asp678Glu0.400
embA4245268p.Asn679Ser0.400
embA4245341c.2109C>T0.611
embA4245344c.2112G>C0.611
embA4245345p.Met705Leu0.611
embA4245355p.Ala708Gly0.550
embA4245368c.2136T>C0.611
embA4245377c.2145T>G0.579
embA4245388p.Ala719Gly0.474
embA4245431c.2199T>C0.300
embA4245446c.2214C>T0.357
embA4245453p.Ala741Thr0.357
embA4245461c.2229C>A0.435
embA4245471p.Ala747Leu0.400
embA4245477p.Met749Leu0.400
embA4245497c.2265C>G0.438
embA4245501p.Ala757Thr0.452
embA4245506c.2274C>T0.467
embA4245518c.2286A>T0.500
embA4245524c.2292G>C0.517
embA4245530c.2298T>C0.433
embA4245531p.Ile767Val0.433
embA4245535p.Ser768Asn0.464
embA4245539c.2307C>G0.481
embA4245557p.Glu775Asp0.414
embA4245560c.2328C>G0.414
embA4245569p.Glu779Asp0.385
embA4245575c.2343C>G0.375
embA4245577p.Lys782Arg0.346
embA4245582p.Asp784Tyr0.320
embA4245645p.Ala805Thr0.359
embA4245650p.Ile806Met0.409
embA4245674c.2442A>C0.270
embA4245678p.Lys816Arg0.200
embA4245693p.Ile821Val0.200
embA4245699p.Gly823Asn0.214
embA4245705p.His825Asn0.231
embA4245709p.Ala826Val0.240
embA4245725c.2493A>C0.333
embA4245726c.2494T>C0.333
embA4245737c.2505A>G0.310
embA4245740c.2508T>C0.310
embA4245743c.2511C>A0.290
embA4245758c.2526C>T0.308
embA4245764c.2532G>C0.296
embA4245845c.2613T>G0.500
embA4245848c.2616C>G0.500
embA4245852p.Ala874Ser0.529
embA4245857c.2625C>G0.545
embA4245885p.Asp885Thr0.536
embA4245892p.Ile887Thr0.517
embA4245899c.2667C>G0.517
embA4245905c.2673C>A0.516
embA4245923c.2691C>G0.500
embA4245980c.2748C>T0.409
embA4245987p.Gln919Glu0.391
embA4245992c.2760C>G0.391
embA4246010c.2778G>C0.400
embA4246013c.2781T>C0.417
embA4246020p.Ala930Thr0.480
embA4246041p.Asp937Asn0.500
embA4246049c.2817G>C0.462
embA4246055c.2823T>C0.409
embA4246058c.2826C>G0.409
embA4246064c.2832T>C0.391
embA4246076c.2844G>C0.300
embA4246079c.2847C>T0.300
embA4246080p.Pro950Ser0.300
embA4246085p.Glu951Asp0.316
embA4246088c.2856A>G0.316
embA4246097c.2865C>G0.316
embA4246109c.2877C>G0.333
embA4246115c.2883T>C0.333
embA4246164c.2932T>C0.450
embA4246184c.2952A>C0.429
embA4246187c.2955C>G0.450
embA4246196c.2964C>G0.409
embA4246205c.2973A>G0.364
embA4246211c.2979T>C0.364
embA4246217c.2985G>A0.300
embA4246220c.2988T>C0.300
embA4246223c.2991C>T0.300
embA4246227p.Ile999Val0.300
embA4246235c.3003G>A0.286
embA4246242p.Gln1004Ala0.286
embA4246253c.3021C>T0.536
embA4246277c.3045G>A0.625
embA4246278p.Ala1016Ser0.600
embA4246316c.3084T>C0.333
embA4246335p.Ala1035Thr0.500
embA4246338c.3106C>T0.500
embA4246341c.3109C>T0.588
embA4246355c.3123G>C0.611
embA4246359p.Ala1043Ser0.647
embA4246364c.3132G>C0.647
embA4246368c.3136C>T0.611
embA4246373c.3141T>C0.550
embA4246376c.3144G>C0.550
embA4246403c.3171G>C0.682
embB4246603c.90C>G0.538
embB4246607p.Ile32Val0.538
embB4246621c.108T>C0.333
embB4246624c.111C>A0.308
embB4246628p.Val39Leu0.308
embB4246636c.123G>C0.267
embB4246639c.126G>C0.267
embB4246645c.132G>A0.267
embB4246651c.138G>A0.267
embB4246652c.139C>T0.267
embB4246657c.144C>G0.267
embB4246882c.369G>C0.438
embB4247059c.546C>T0.474
embB4247062c.549G>C0.450
embB4247065c.552G>A0.450
embB4247068c.555T>C0.440
embB4247089c.576G>C0.500
embB4247091p.Thr193Ser0.500
embB4247095c.582G>T0.478
embB4247101c.588G>C0.458
embB4247107c.594C>G0.458
embB4247114p.Ala201Asn0.458
embB4247117p.Val202Phe0.458
embB4247140c.627G>C0.480
embB4247425c.912G>C0.400
embB4247437c.924A>G0.433
embB4247452c.939C>G0.469
embB4247470c.957T>C0.533
embB4247497c.984T>C0.424
embB4247500c.987C>G0.406
embB4247506c.993C>G0.406
embB4247512c.999T>C0.344
embB4247527c.1014G>C0.300
embB4247539c.1026T>C0.290
embB4247550p.Ala346Asp0.312
embB4247554c.1041T>C0.333
embB4247566c.1053C>G0.382
embB4247572c.1059A>C0.395
embB4247590c.1077A>G0.325
embB4247629c.1116C>G0.306
embB4247632c.1119C>G0.324
embB4247638c.1125G>C0.324
embB4247645p.Glu378Thr0.300
embB4247648p.Ala379Ser0.290
embB4247656c.1143A>G0.273
embB4247657p.Pro382Ala0.273
embB4247662c.1149C>G0.281
embB4247677c.1164C>G0.372
embB4247684c.1171T>C0.395
embB4247722c.1209G>T0.303
embB4247725c.1212G>C0.303
embB4247729p.Gly406Pro0.303
embB4247753p.Val414Ile0.382
embB4247761c.1248T>C0.320
embB4247764c.1251G>A0.320
embB4247951p.Ser480Ala0.421
embB4247971c.1458C>A0.500
embB4247972p.Thr487Phe0.500
embB4247983c.1470G>C0.609
embB4248007c.1494C>A0.682
embB4248035p.Val508Ile0.619
embB4248041p.Ala510Thr0.625
embB4248044p.Lys511Ala0.625
embB4248055c.1542G>C0.600
embB4248064c.1551G>C0.600
embB4248070c.1557T>C0.611
embB4248073c.1560C>T0.333
embB4248085c.1572T>C0.632
embB4248097c.1584C>G0.611
embB4248118c.1605T>G0.615
embB4248127c.1614G>C0.615
embB4248157c.1644A>G0.688
embB4248161c.1648C>T0.688
embB4248169c.1656C>G0.688
embB4248190c.1677G>C0.812
embB4248200p.Ile563Val0.833
embB4248206p.Ser565Gly0.933
embB4248211c.1698G>A0.938
embB4248220c.1707A>C0.938
embB4248241c.1728C>T1.000
embB4248277c.1764G>C1.000
embB4248298c.1785C>T0.692
embB4248304c.1791G>C0.667
embB4248316c.1803C>G0.600
embB4248319c.1806A>G0.600
embB4248322c.1809G>C0.417
embB4248469c.1956C>T0.400
embB4248472c.1959T>C0.400
embB4248478c.1965G>A0.400
embB4248757c.2244A>T0.222
embB4248772c.2259A>G0.200
embB4248943c.2430C>G0.684
embB4248967c.2454G>T0.676
embB4248968p.Thr819Leu0.667
embB4248981p.Ser823Lys0.697
embB4248985c.2472T>G0.697
embB4248994c.2481T>C0.657
embB4248997c.2484T>C0.657
embB4249000c.2487T>G0.657
embB4249018c.2505T>C0.686
embB4249136p.Val875Ile0.458
embB4249158p.Lys882Thr0.458
embB4249163p.Ala884Ser0.458
embB4249339c.2826T>C0.167
embB4249342c.2829C>G0.167
embB4249351c.2838C>G0.200
embB4249360c.2847G>C0.250
embB4249366p.Glu951Asp0.263
embB4249375c.2862G>C0.238
embB4249381c.2868A>G0.238
embB4249387p.Glu958Asp0.238
ethA4326253c.1221A>G0.385
ethA4326258c.1216A>G0.385
ethA4326262c.1212G>T0.357
ethA4326265c.1209A>G0.357
ethA4326271c.1203A>G0.357
ethA4326277c.1197C>G0.357
ethA4326280c.1194C>G0.357
ethA4326286c.1188G>A0.357
ethA4326295c.1179C>T0.385
ethA4326304c.1170G>A0.455
ethA4326307c.1167G>T0.385
ethA4326310c.1164A>G0.385
ethA4326847c.627G>C0.219
ethA4326850c.624T>C0.226
ethA4326964c.510G>A0.200
ethA4326976c.498G>A0.211
ethA4327061p.Ser138Thr0.556
ethA4327389p.Thr29Ser0.667
ethA4327396c.78A>C0.636
ethA4327399p.Asp25Glu0.636
ethA4327414c.60G>T0.750
ethA4327420c.54G>A0.750
ethA4327423c.51G>C0.750
ethA4327435c.39T>G0.900
ethA4327438c.36A>G0.900
ethA4327453c.21A>G0.818
ethA4327468c.6G>A0.800
ethR4327680c.132T>C0.643
ethR4327695c.147T>C0.500
ethR4327703p.Lys52Arg0.500
ethR4327713c.165T>G0.412
ethR4327714p.Ile56Leu0.412
ethR4327720c.172A>C0.421
gid4407603c.600C>T0.625
gid4407614p.Arg197Cys0.652
gid4407622p.Asn194Ser0.680
gid4407667p.Ile179Thr0.250
gid4407762c.441T>C0.250
gid4407770c.433A>G0.250
gid4407910p.Thr98Ser0.389
gid4407921c.282T>G0.389

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;