TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5dca3fedae637
Sample: 5dca3fedae637

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Summary
ID: 5dca3fedae637
Date: Tue Nov 12 05:18:40 2019
Strain: lineage1.1.2;lineage2.2.1.1;lineage4.3;lineage4.2;lineage4.1.1;lineage4.4.1
Drug-resistance: Drug-resistant

Drug1ResistanceSupporting Mutations (frequency)
Isoniazid
Rifampicin
EthambutolRembB p.His312Arg (0.33), embB p.Leu359Ile (0.18), embB p.Asn399Asp (0.14)
PyrazinamideRpanD p.Val138Ala (0.14)
StreptomycinRrrs r.462c>t (0.32)
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage1Indo-OceanicEAIRD239
lineage2East-AsianBeijingRD105
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.2Euro-AmericanH;T;LAMNone
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.4.1Euro-American (S-type)S;TNone
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5359c.120C>T0.205
gyrB5363c.124T>C0.205
gyrB5371c.132T>C0.243
gyrB5377c.138T>C0.247
gyrB5389c.150C>G0.198
gyrB5396p.Ala53Ser0.198
gyrB5416c.177C>A0.189
gyrB5611c.372C>T0.263
gyrB5623c.384T>C0.232
gyrB5632c.393A>C0.185
gyrB5635c.396C>G0.183
gyrB5647c.408A>G0.177
gyrB5992c.753T>C0.197
gyrB5998c.759T>C0.210
gyrB6001c.762G>C0.224
gyrB6013c.774G>C0.234
gyrB6022c.783G>C0.239
gyrB6112p.Met291Ile0.861
gyrB6115c.876A>G0.147
gyrB6123p.Ala295Gly0.147
gyrB6127c.888G>C0.149
gyrB6130c.891T>C0.185
gyrB6184c.945C>G0.248
gyrB6190c.951A>G0.267
gyrB6215p.Ser326Thr0.261
gyrB6223c.984G>C0.306
gyrB6238c.999G>A0.253
gyrB6242p.Arg335Lys0.245
gyrB6250c.1011A>G0.243
gyrB6253c.1014G>C0.253
gyrB6280c.1041T>C0.245
gyrB6283c.1044C>T0.260
gyrB6286c.1047T>C0.278
gyrB6292c.1053G>C0.288
gyrB6307c.1068T>G0.316
gyrB6319c.1080G>C0.350
gyrB6331c.1092A>G0.345
gyrB6362c.1123T>C0.301
gyrB6379c.1140C>G0.250
gyrB6382c.1143A>G0.248
gyrB6385c.1146G>C0.250
gyrB6388c.1149T>C0.265
gyrB6403c.1164T>C0.283
gyrB6412c.1173G>A0.255
gyrB6415c.1176G>C0.255
gyrB6418c.1179C>G0.243
gyrB6427c.1188T>C0.288
gyrB6565c.1326G>C0.190
gyrB6571c.1332T>C0.192
gyrB6577c.1338T>C0.213
gyrB6583c.1344G>C0.247
gyrB6598c.1359C>G0.261
gyrB6610c.1371C>G0.265
gyrB6613c.1374A>G0.284
gyrB6616c.1377A>G0.286
gyrB6634c.1395T>C0.268
gyrB6637c.1398T>G0.265
gyrB6640c.1401A>C0.268
gyrB6643c.1404A>G0.280
gyrB6649c.1410T>C0.359
gyrB6655c.1416T>C0.359
gyrB6670c.1431G>C0.422
gyrB6673c.1434A>C0.422
gyrB6676c.1437T>G0.427
gyrB6700c.1461T>C0.237
gyrB6703c.1464G>C0.224
gyrB6706c.1467G>A0.221
gyrB6709c.1470A>G0.230
gyrB6712c.1473G>C0.230
gyrB6718c.1479C>T0.239
gyrB6727c.1488G>T0.260
gyrB6728c.1489C>T0.278
gyrB6742c.1503A>G0.299
gyrB6745c.1506T>C0.315
gyrB6775c.1536G>C0.302
gyrB6793c.1554T>C0.262
gyrB6798p.Gly520Ala0.260
gyrB6838c.1599C>G0.163
gyrB6841c.1602T>C0.136
gyrB6844c.1605T>C0.141
gyrB6853c.1614A>G0.133
gyrB6856c.1617T>C0.136
gyrB6859c.1620T>C0.150
gyrB6862c.1623C>G0.150
gyrB6866c.1627C>T0.164
gyrB6869c.1630T>C0.169
gyrB6872c.1633T>C0.167
gyrB6878c.1639T>C0.169
gyrB6881c.1642T>C0.169
gyrB6904c.1665C>G0.317
gyrB6910c.1671G>A0.321
gyrB6911p.Asn558His0.325
gyrB6919c.1680T>C0.346
gyrB6925c.1686T>C0.346
gyrB6931c.1692A>G0.342
gyrB6949c.1710A>G0.375
gyrB6955c.1716G>A0.389
gyrB6961c.1722G>A0.394
gyrB6967c.1728T>C0.333
gyrB6970c.1731C>T0.291
gyrB6973c.1734G>C0.286
gyrB6982c.1743A>C0.325
gyrB7006c.1767T>C0.319
gyrB7007c.1768C>T0.324
gyrB7018c.1779G>C0.313
gyrB7021c.1782G>C0.277
gyrB7023p.Leu595Gln0.269
gyrB7030c.1791C>G0.265
gyrB7033c.1794G>C0.269
gyrB7051p.Glu604Asp0.303
gyrB7057c.1818C>T0.268
gyrB7060c.1821T>C0.236
gyrB7066c.1827G>T0.208
gyrB7078c.1839A>C0.216
gyrB7084c.1845A>G0.239
gyrB7093c.1854T>C0.247
gyrB7099c.1860G>A0.232
gyrB7108c.1869G>A0.247
gyrB7114c.1875C>G0.235
gyrB7124p.Ser629Thr0.156
gyrB7129c.1890T>C0.160
gyrB7132c.1893T>G0.150
gyrB7136c.1897T>C0.148
gyrB7141c.1902T>C0.163
gyrB7147c.1908G>C0.165
gyrB7150c.1911G>C0.163
gyrB7153c.1914G>C0.171
gyrB7165c.1926C>G0.296
gyrB7178c.1939T>C0.322
gyrB7190c.1951C>T0.310
gyrB7210c.1971C>T0.324
gyrB7216c.1977G>C0.309
gyrB7234c.1995C>T0.239
gyrB7237c.1998C>T0.239
gyrB7252c.2013G>C0.167
gyrB7256c.2017C>T0.185
gyrA7347p.Glu16Gln0.222
gyrA7355c.54T>C0.238
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T0.208
gyrA7394c.93T>C0.223
gyrA7415c.114C>G0.255
gyrA7418c.117C>T0.247
gyrA7427c.126G>C0.278
gyrA7442c.141G>T0.293
gyrA7451c.150C>G0.302
gyrA7457c.156T>C0.314
gyrA7466c.165G>C0.330
gyrA7475c.174A>G0.351
gyrA7480p.Phe60Tyr0.345
gyrA7484c.183T>C0.351
gyrA7490c.189C>G0.350
gyrA7523c.222C>G0.369
gyrA7526c.225G>C0.380
gyrA7532c.231T>G0.387
gyrA7541c.240C>G0.378
gyrA7547c.246C>T0.370
gyrA7553c.252C>T0.364
gyrA7559c.258G>C0.345
gyrA7585p.Ser95Thr1.000
gyrA7601c.300C>G0.273
gyrA7607c.306C>G0.253
gyrA7626c.325C>T0.226
gyrA7631c.330G>C0.217
gyrA7637c.336C>G0.229
gyrA7652c.351C>T0.220
gyrA7658c.357A>C0.237
gyrA7664c.363T>C0.231
gyrA7670c.369A>G0.250
gyrA7676c.375G>C0.221
gyrA7679c.378G>C0.221
gyrA7683c.382A>C0.211
gyrA7694c.393A>G0.212
gyrA7697c.396C>G0.220
gyrA7700c.399G>A0.214
gyrA7710c.409T>C0.284
gyrA7728c.427A>C0.314
gyrA7763c.462T>C0.349
gyrA7775c.474C>T0.325
gyrA7778c.477G>T0.305
gyrA7784c.483A>G0.338
gyrA7787c.486G>A0.343
gyrA7793c.492G>C0.389
gyrA7799c.498A>G0.417
gyrA7817c.516C>T0.375
gyrA7832c.531G>C0.323
gyrA7835c.534A>G0.265
gyrA7841c.540C>T0.268
gyrA7847c.546G>C0.268
gyrA7850c.549C>G0.282
gyrA7853c.552C>G0.267
gyrA7859c.558A>G0.326
gyrA7865c.564T>C0.341
gyrA7886c.585T>C0.330
gyrA7898p.Asp199Glu0.247
gyrA7901c.600G>C0.230
gyrA7904c.603G>C0.221
gyrA7906p.Phe202Tyr0.212
gyrA7911p.Ala204Cys0.229
gyrA7919p.Glu206Asp0.298
gyrA7928p.Asp209Glu0.298
gyrA7942p.Glu214Ala0.304
gyrA7946c.645C>G0.297
gyrA7950p.Ala217Thr0.295
gyrA8069c.768T>C0.289
gyrA8090c.789C>A0.333
gyrA8096c.795T>C0.320
gyrA8099c.798T>C0.323
gyrA8105c.804G>C0.311
gyrA8126c.825G>C0.255
gyrA8129c.828T>C0.252
gyrA8135c.834C>G0.240
gyrA8147c.846C>T0.264
gyrA8156c.855T>C0.294
gyrA8168c.867A>G0.299
gyrA8174c.873C>G0.284
gyrA8177c.876A>C0.284
gyrA8187c.886C>T0.272
gyrA8198c.897T>C0.259
gyrA8207c.906T>C0.268
gyrA8219c.918T>C0.216
gyrA8264c.963T>C0.175
gyrA8267c.966G>C0.188
gyrA8283p.Ile328Leu0.152
gyrA8288c.987T>C0.150
gyrA8294c.993T>C0.204
gyrA8324c.1023T>C0.219
gyrA8327c.1026C>G0.222
gyrA8330c.1029C>G0.229
gyrA8339c.1038A>G0.234
gyrA8340p.Ala347Ser0.241
gyrA8354c.1053G>T0.294
gyrA8372c.1071G>C0.320
gyrA8375c.1074G>C0.308
gyrA8382p.Leu361Met0.305
gyrA8391p.Tyr364His0.176
gyrA8399c.1098T>C0.178
gyrA8401p.Asp367Ala0.176
gyrA8405c.1104C>T0.180
gyrA8417c.1116C>G0.299
gyrA8420c.1119T>C0.310
gyrA8423c.1122G>C0.306
gyrA8452p.Ala384Val0.691
gyrA8462c.1161A>T0.211
gyrA8465c.1164C>G0.205
gyrA8471c.1170T>C0.203
gyrA8472c.1171C>T0.217
gyrA8480c.1179C>T0.286
gyrA8486c.1185T>C0.267
gyrA8504c.1203G>C0.307
gyrA8513c.1212C>G0.266
gyrA8516c.1215T>C0.256
gyrA8519c.1218A>C0.256
gyrA8528c.1227G>C0.271
gyrA8546p.Asp415Glu0.317
gyrA8561c.1260A>C0.290
gyrA8576c.1275C>G0.302
gyrA8603c.1302A>G0.333
gyrA8619c.1318T>C0.348
gyrA8624c.1323G>T0.327
gyrA8627c.1326C>G0.330
gyrA8636c.1335A>C0.318
gyrA8637c.1336C>T0.312
gyrA8642c.1341A>G0.327
gyrA8672c.1371A>G0.352
gyrA8678c.1377G>A0.336
gyrA8690c.1389C>G0.346
gyrA8693c.1392T>C0.343
gyrA8711c.1410A>C0.356
gyrA8714c.1413A>G0.344
gyrA8717c.1416C>T0.386
gyrA8729c.1428T>C0.354
gyrA8730p.Gly477Arg0.354
gyrA8740p.Arg480His0.435
gyrA8747c.1446A>G0.364
gyrA8756c.1455A>G0.344
gyrA8762c.1461G>C0.345
gyrA8767p.Arg489Lys0.363
gyrA8780p.Asp493Glu0.362
gyrA8783c.1482G>C0.358
gyrA8786c.1485T>G0.366
gyrA8801c.1500G>C0.384
gyrA8810c.1509A>T0.376
gyrA8818p.Ser506Asn0.370
gyrA8828c.1527T>C0.361
gyrA8829c.1528T>C0.361
gyrA8852c.1551T>C0.389
gyrA8858c.1557T>C0.389
gyrA8867c.1566A>G0.411
gyrA8870c.1569G>C0.406
gyrA8873c.1572A>T0.427
gyrA8882c.1581G>A0.467
gyrA8897c.1596T>C0.424
gyrA8903c.1602T>C0.423
gyrA8930c.1629C>T0.381
gyrA8939c.1638T>C0.305
gyrA8942c.1641G>C0.293
gyrA8945c.1644G>C0.296
gyrA8946c.1645T>C0.316
gyrA8966c.1665C>G0.333
gyrA8967p.Ala556Arg0.333
gyrA8990c.1689C>G0.317
gyrA8996c.1695T>C0.293
gyrA8998p.Leu566Trp0.293
gyrA9017c.1716C>G0.306
gyrA9023c.1722A>C0.231
gyrA9026c.1725G>C0.225
gyrA9029c.1728T>C0.225
gyrA9032c.1731T>C0.286
gyrA9044c.1743C>G0.338
gyrA9047c.1746C>T0.671
gyrA9050p.Asp583Glu0.254
gyrA9051c.1750T>C0.265
gyrA9056c.1755C>G0.265
gyrA9062c.1761C>G0.231
gyrA9065c.1764C>G0.235
gyrA9068c.1767G>A0.235
gyrA9074c.1773G>A0.354
gyrA9080c.1779G>T0.362
gyrA9089c.1788G>C0.340
gyrA9099c.1798T>C0.316
gyrA9104c.1803C>G0.316
gyrA9110c.1809G>A0.356
gyrA9119c.1818A>G0.366
gyrA9143c.1842T>C1.000
gyrA9153p.Thr618Glu0.295
gyrA9182c.1881T>C0.364
gyrA9191c.1890G>T0.374
gyrA9200c.1899A>G0.390
gyrA9204p.Ser635Thr0.415
gyrA9230c.1929T>C0.371
gyrA9242c.1941A>C0.389
gyrA9252p.Val651Ile0.388
gyrA9258c.1957C>T0.363
gyrA9278c.1977G>C0.374
gyrA9284c.1983T>C0.370
gyrA9293c.1992G>C0.302
gyrA9296c.1995T>C0.295
gyrA9299c.1998G>C0.292
gyrA9304p.Gly668Asp1.000
gyrA9308p.Asp669Glu0.297
gyrA9318c.2017C>T0.321
gyrA9335c.2034G>C0.358
gyrA9345c.2044A>C0.364
gyrA9365c.2064G>A0.352
gyrA9374c.2073G>C0.330
gyrA9377c.2076A>G0.333
gyrA9383c.2082T>C0.344
gyrA9386c.2085T>C0.330
gyrA9443c.2142G>A1.000
gyrA9479c.2178G>C0.283
gyrA9485c.2184A>G0.246
gyrA9488c.2187G>T0.246
gyrA9491c.2190C>G0.238
gyrA9497c.2196G>C0.238
gyrA9500c.2199A>G0.238
gyrA9503c.2202T>C0.224
gyrA9518c.2217A>G0.307
gyrA9521c.2220C>T0.307
gyrA9527c.2226A>G0.329
gyrA9542c.2241T>C0.284
gyrA9545c.2244A>G0.241
gyrA9548c.2247T>C0.260
gyrA9551c.2250G>C0.243
gyrA9560c.2259C>G0.277
gyrA9578c.2277C>T0.220
gyrA9585c.2284T>C0.204
gyrA9593c.2292G>T0.211
gyrA9608c.2307C>T0.184
gyrA9611p.Asp770Glu0.189
gyrA9662c.2361G>A0.155
gyrA9665c.2364A>G0.169
gyrA9666p.Arg789Gly0.172
gyrA9671c.2370G>A0.164
gyrA9674c.2373T>C0.176
rpoB759546c.-261A>G1.000
rpoB759571c.-236C>G0.364
rpoB759606c.-201T>C0.374
rpoB759629c.-178T>C0.297
rpoB759644c.-163T>A0.172
rpoB759647c.-160T>C0.159
rpoB759817p.Ser4Phe0.254
rpoB760040c.234T>C0.315
rpoB760067c.261G>C0.354
rpoB760070c.264T>G0.381
rpoB760085c.279C>T0.407
rpoB760091c.285G>C0.402
rpoB760101c.295T>C0.387
rpoB760112c.306T>C0.404
rpoB760118c.312T>G0.406
rpoB760130p.Asp108Glu0.402
rpoB760139c.333A>G0.400
rpoB760142c.336C>G0.412
rpoB760181c.375T>C0.387
rpoB760184c.378A>G0.410
rpoB760196c.390C>G0.424
rpoB760223c.417T>C0.400
rpoB760235c.429T>C0.352
rpoB760283c.477G>C0.354
rpoB760298c.492G>C0.337
rpoB760310c.504G>C0.316
rpoB760328c.522G>C0.321
rpoB760331c.525G>C0.316
rpoB760340c.534G>C0.312
rpoB760361c.555T>C0.375
rpoB760376p.Asp190Glu0.357
rpoB760380p.Thr192Leu0.312
rpoB760406c.600G>C0.391
rpoB760412c.606C>G0.359
rpoB760418c.612G>C0.354
rpoB760424c.618C>G0.337
rpoB760430c.624T>C0.346
rpoB760460c.654G>C0.342
rpoB760475c.669A>G0.354
rpoB760481c.675G>C0.329
rpoB760484c.678A>G0.338
rpoB760487c.681G>C0.333
rpoB760490c.684C>T0.657
rpoB760511c.705G>C0.368
rpoB760522p.Ser239Asn0.328
rpoB760532c.726T>C0.340
rpoB760533p.Val243Thr0.345
rpoB760547c.741G>C0.484
rpoB760563p.Arg253Met0.397
rpoB760591p.Val262Ala0.400
rpoB760611c.805T>C0.380
rpoB760646c.840C>G0.333
rpoB760655c.849A>G0.333
rpoB760661c.855A>C0.284
rpoB760670c.864G>C0.270
rpoB760674c.868T>C0.287
rpoB760679c.873A>G0.281
rpoB760683c.877T>C0.312
rpoB760724c.918T>C0.400
rpoB760727c.921C>T0.395
rpoB760730c.924T>C0.403
rpoB760751c.945G>C0.316
rpoB760755p.His317Asn0.312
rpoB760760c.954C>G0.316
rpoB760769c.963C>G0.321
rpoB760776c.970T>A0.307
rpoB760793c.987A>G0.444
rpoB760805c.999G>C0.464
rpoB760817c.1011A>G0.420
rpoB760820c.1014T>C0.407
rpoB760826c.1020C>G0.407
rpoB760830c.1024T>C0.446
rpoB760841c.1035T>C0.451
rpoB760845p.Thr347Ala0.451
rpoB760859c.1053T>C0.321
rpoB760862c.1056G>C0.333
rpoB760869p.Val355Thr0.375
rpoB760886c.1080A>G0.368
rpoB760916c.1110C>G0.284
rpoB760919c.1113C>G0.259
rpoB760920c.1114C>T0.259
rpoB760925c.1119T>C0.270
rpoB760934c.1128C>T0.308
rpoB760946c.1140A>G0.301
rpoB760970c.1164G>C0.300
rpoB760982c.1176G>C0.284
rpoB760985c.1179G>C0.258
rpoB760988c.1182C>G0.246
rpoB760991c.1185G>C0.270
rpoB761021c.1215G>C0.315
rpoB761027c.1221A>G0.287
rpoB761036c.1230G>C0.299
rpoB761037c.1231T>C0.299
rpoB761057c.1251G>C0.402
rpoB761097c.1291A>T0.298
rpoB761102c.1296A>G0.309
rpoB761129c.1323G>C0.326
rpoB761133c.1327T>C0.323
rpoB761147c.1341C>T0.330
rpoB761150c.1344A>C0.333
rpoB761153c.1347G>C0.337
rpoB761171c.1365C>T0.297
rpoB761180c.1374A>C0.294
rpoB761189c.1383T>C0.316
rpoB761195c.1389G>C0.327
rpoB761207c.1401C>T0.330
rpoB761213c.1407G>C0.320
rpoB761234c.1428G>C0.337
rpoB761249c.1443A>G0.337
rpoB761255c.1449T>G0.377
rpoB761261c.1455G>T0.370
rpoB761264c.1458C>G0.378
rpoB761300c.1494G>C0.407
rpoB761318c.1512G>C0.357
rpoB761327c.1521A>G0.374
rpoB761354c.1548C>T0.385
rpoB761360c.1554T>C0.338
rpoB761361c.1555A>T0.333
rpoB761373p.Val523His0.318
rpoB761408c.1602G>C0.301
rpoB761414c.1608A>G0.290
rpoB761423c.1617T>C0.293
rpoB761435c.1629T>C0.145
rpoB761437p.Ala544Asp0.129
rpoB761439p.Asp545Lys0.133
rpoB761444c.1638T>C0.139
rpoB761447c.1641C>G0.139
rpoB761452p.Val549Glu0.147
rpoB761457p.Pro551Ser0.151
rpoB761465c.1659G>C0.295
rpoB761492c.1686G>C0.372
rpoB761501c.1695G>C0.315
rpoB761504c.1698C>G0.301
rpoB761507c.1701G>C0.306
rpoB761510c.1704T>C0.338
rpoB761531c.1725C>G0.371
rpoB761537c.1731C>G0.383
rpoB761561c.1755C>G0.429
rpoB761564c.1758G>C0.427
rpoB761570c.1764T>C0.411
rpoB761573c.1767C>G0.416
rpoB761579c.1773G>C0.435
rpoB761600c.1794T>C0.462
rpoB761606c.1800C>G0.458
rpoB761612c.1806G>T0.447
rpoB761615c.1809A>C0.438
rpoB761636c.1830G>T0.462
rpoB761645c.1839C>G0.442
rpoB761648c.1842T>C0.455
rpoB761657c.1851C>G0.472
rpoB761675c.1869G>C0.422
rpoB761747c.1941G>C0.271
rpoB761750c.1944G>C0.274
rpoB761765c.1959T>C0.358
rpoB761772p.His656Ala0.330
rpoB761778p.Asn658Asp0.333
rpoB761791p.Arg662His0.318
rpoB761813c.2007T>C0.290
rpoB761815p.Ala670Glu0.279
rpoB761834c.2028T>C0.344
rpoB761848p.Cys681Ser0.205
rpoB761852c.2046C>G0.202
rpoB761858c.2052G>C0.193
rpoB761864c.2058G>C0.195
rpoB761867c.2061C>T0.193
rpoB761870p.Asp688Glu0.193
rpoB761873c.2067A>G0.191
rpoB761876c.2070C>G0.189
rpoB761891c.2085G>C0.320
rpoB761906c.2100C>G0.320
rpoB761909c.2103T>C0.307
rpoB761912c.2106T>C0.315
rpoB761915p.Asp703Glu0.311
rpoB761916p.Asp704Asn0.307
rpoB761933c.2127G>C0.310
rpoB761948c.2142G>C0.306
rpoB761954c.2148C>G0.276
rpoB761969c.2163G>A0.277
rpoB761972c.2166C>G0.268
rpoB762014c.2208C>T0.211
rpoB762017c.2211A>G0.219
rpoB762053c.2247T>C0.260
rpoB762062c.2256T>C0.255
rpoB762065c.2259T>C0.260
rpoB762083c.2277T>C0.277
rpoB762086c.2280G>C0.261
rpoB762101c.2295C>G0.269
rpoB762114p.Ile770Val0.274
rpoB762131c.2325C>G0.266
rpoB762143c.2337T>C0.272
rpoB762149c.2343G>C0.283
rpoB762176c.2370T>C0.247
rpoB762185c.2379G>C0.264
rpoB762233c.2427G>C0.372
rpoB762254c.2448T>C0.404
rpoB762257c.2451C>G0.402
rpoB762266c.2460T>C0.346
rpoB762284c.2478G>C0.366
rpoB762293c.2487T>C0.369
rpoB762296c.2490G>A0.371
rpoB762317c.2511A>G0.333
rpoB762329c.2523G>C0.330
rpoB762338c.2532T>C0.311
rpoB762347c.2541T>C0.330
rpoB762362p.Glu852Asp0.337
rpoB762369c.2563T>C0.380
rpoB762398c.2592T>C0.383
rpoB762401c.2595G>C0.369
rpoB762404c.2598T>C0.393
rpoB762410c.2604T>C0.394
rpoB762416c.2610A>G0.349
rpoB762443c.2637G>C0.355
rpoB762449c.2643C>A0.324
rpoB762452c.2646G>C0.321
rpoB762470c.2664G>C0.307
rpoB762489p.Val895Gln0.254
rpoB762509c.2703T>G0.239
rpoB762510p.Ala902Pro0.239
rpoB762521c.2715C>G0.270
rpoB762533c.2727T>C0.258
rpoB762536c.2730T>C0.266
rpoB762537c.2731T>C0.269
rpoB762551c.2745C>T0.340
rpoB762581c.2775T>C0.337
rpoB762729p.Gln975Lys0.293
rpoB762736p.Ala977Glu0.208
rpoB762744p.Gln980Ala0.200
rpoB762750p.Leu982Met0.190
rpoB762753c.2947T>C0.206
rpoB762758c.2952G>C0.203
rpoB762782c.2976T>C0.192
rpoB762785p.Asp993Glu0.197
rpoB762788c.2982G>C0.195
rpoB762789p.Leu995Met0.195
rpoB762799p.Ala998Gly0.326
rpoB762812c.3006C>G0.323
rpoB762813p.Met1003Val0.326
rpoB762818c.3012C>G0.333
rpoB762827c.3021G>C0.367
rpoB762860c.3054G>C0.438
rpoB762929c.3123G>T0.397
rpoB762947c.3141C>G0.395
rpoB762962c.3156C>T0.446
rpoB762983c.3177C>T0.390
rpoB762989c.3183G>C0.370
rpoB762995c.3189G>T0.391
rpoB763028c.3222T>C0.358
rpoB763031c.3225T>C0.368
rpoB763034c.3228C>G0.382
rpoB763040c.3234C>G0.375
rpoB763070c.3264T>C0.374
rpoB763085c.3279C>G0.364
rpoB763097c.3291C>T0.371
rpoB763115c.3309T>C0.402
rpoB763136c.3330C>T0.360
rpoB763139c.3333C>T0.354
rpoB763148c.3342G>C0.375
rpoB763158c.3352C>T0.318
rpoB763166c.3360A>G0.312
rpoB763169c.3363A>G0.319
rpoB763181c.3375G>C0.347
rpoB763202c.3396A>C0.226
rpoB763205c.3399G>C0.213
rpoB763206c.3400A>T0.213
rpoB763226c.3420A>G0.206
rpoB763227c.3421C>T0.206
rpoB763238c.3432T>C0.246
rpoB763247c.3441G>A0.220
rpoB763253c.3447G>C0.220
rpoB763262c.3456C>A0.200
rpoB763268c.3462C>G0.169
rpoB763283c.3477T>C0.167
rpoC763351c.-19T>C0.261
rpoC763352c.-18T>A0.257
rpoC763402c.33C>T0.356
rpoC763408c.39T>C0.304
rpoC763411c.42T>G0.300
rpoC763414c.45T>C0.290
rpoC763441c.72C>T0.384
rpoC763444c.75T>C0.377
rpoC763456c.87A>G0.369
rpoC763486c.117T>G0.414
rpoC763528c.159G>A0.349
rpoC763546c.177A>G0.341
rpoC763573c.204G>C0.314
rpoC763576c.207C>G0.306
rpoC763594c.225C>T0.297
rpoC763636c.267T>C0.321
rpoC763648c.279C>T0.354
rpoC763660c.291T>G0.337
rpoC763666c.297G>T0.349
rpoC763675c.306C>G0.350
rpoC763696c.327T>C0.347
rpoC763702c.333C>G0.323
rpoC763714c.345G>C0.286
rpoC763717c.348T>C0.276
rpoC763723c.354G>C0.287
rpoC763732c.363C>G0.282
rpoC763735c.366G>C0.279
rpoC763741c.372C>T0.284
rpoC763744c.375G>C0.287
rpoC763765c.396T>C0.273
rpoC763774c.405G>C0.280
rpoC763807c.438T>C0.273
rpoC763819c.450G>C0.289
rpoC763835p.Ala156Met0.310
rpoC763853p.Val162Ile0.254
rpoC763858c.489A>G0.231
rpoC763872p.Gly168Ala0.360
rpoC763876p.Glu169Asp0.341
rpoC763879c.510A>G0.367
rpoC763884p.Ala172Val0.593
rpoC763886p.Arg173Ser0.580
rpoC763891c.522G>C0.389
rpoC763894c.525A>G0.391
rpoC763900c.531G>C0.393
rpoC763936c.567C>G0.420
rpoC763939c.570G>A0.408
rpoC763951c.582G>C0.407
rpoC763987c.618C>T0.337
rpoC763991p.Ile208Leu0.330
rpoC763996c.627T>C0.320
rpoC764005c.636G>C0.346
rpoC764011c.642T>C0.296
rpoC764024c.655T>C0.319
rpoC764032p.Asp221Glu0.270
rpoC764040p.Ser224Thr0.229
rpoC764044c.675T>C0.228
rpoC764059c.690G>C0.293
rpoC764083c.714A>G0.250
rpoC764098c.729A>G0.169
rpoC764101c.732C>G0.163
rpoC764102p.Val245Ile0.163
rpoC764110c.741C>G0.190
rpoC764112p.Tyr248Phe0.205
rpoC764116c.747C>T0.208
rpoC764131c.762T>C0.253
rpoC764188c.819A>G0.250
rpoC764195p.Ser276Ile0.250
rpoC764203c.834G>C0.257
rpoC764206c.837T>C0.257
rpoC764215c.846A>G0.277
rpoC764257c.888G>C0.299
rpoC764266c.897T>C0.297
rpoC764269c.900G>C0.288
rpoC764272c.903G>C0.308
rpoC764278c.909A>G0.359
rpoC764344c.975C>G0.421
rpoC764365c.996C>T0.398
rpoC764374c.1005C>T0.386
rpoC764380c.1011G>C0.359
rpoC764387c.1018T>C0.342
rpoC764405c.1036A>C0.382
rpoC764428c.1059G>C0.325
rpoC764431c.1062G>C0.325
rpoC764434c.1065A>G0.342
rpoC764446c.1077T>C0.296
rpoC764449c.1080G>C0.279
rpoC764452c.1083T>C0.280
rpoC764458c.1089G>C0.267
rpoC764461c.1092A>G0.271
rpoC764497c.1128A>G0.360
rpoC764503c.1134G>C0.392
rpoC764521c.1152T>C0.371
rpoC764527c.1158C>T0.341
rpoC764530c.1161C>T0.322
rpoC764536c.1167G>T0.307
rpoC764539c.1170C>G0.321
rpoC764554c.1185C>T0.381
rpoC764560c.1191T>C0.372
rpoC764566c.1197C>G0.323
rpoC764575c.1206T>G0.366
rpoC764578c.1209C>G0.371
rpoC764593c.1224C>T0.364
rpoC764611c.1242G>C0.388
rpoC764626c.1257C>T0.327
rpoC764632c.1263T>C0.340
rpoC764650c.1281G>T0.340
rpoC764716c.1347G>C0.370
rpoC764746c.1377G>A0.371
rpoC764752c.1383G>C0.392
rpoC764758c.1389C>G0.402
rpoC764764c.1395T>C0.402
rpoC764809c.1440C>T0.373
rpoC764815c.1446A>G0.345
rpoC764827c.1458G>C0.348
rpoC764858c.1489T>C0.298
rpoC764872c.1503A>G0.325
rpoC764887c.1518G>C0.286
rpoC764888c.1519T>C0.277
rpoC764893c.1524T>C0.286
rpoC764911c.1542A>G0.283
rpoC764923c.1554A>G0.267
rpoC764932c.1563C>A0.241
rpoC764948c.1579T>C0.248
rpoC764968c.1599T>C0.247
rpoC764971c.1602C>G0.256
rpoC764995c.1626C>G0.144
rpoC765019c.1650A>G0.128
rpoC765034c.1665T>A0.120
rpoC765073c.1704G>C0.232
rpoC765076c.1707A>G0.232
rpoC765079c.1710T>C0.232
rpoC765082c.1713G>C0.232
rpoC765085c.1716T>A0.232
rpoC765089c.1720T>C0.234
rpoC765103c.1734G>T0.316
rpoC765121c.1752G>T0.321
rpoC765171p.Pro601Leu1.000
rpoC765287c.1918C>T0.337
rpoC765292c.1923G>T0.330
rpoC765300p.Val644Ala0.322
rpoC765319c.1950A>G0.350
rpoC765326p.His653Ala0.327
rpoC765330p.Ser654Asn0.344
rpoC765343c.1974G>C0.333
rpoC765352c.1983G>C0.260
rpoC765356p.Met663Leu0.257
rpoC765370c.2001G>C0.263
rpoC765379c.2010G>T0.260
rpoC765383p.Met672Leu0.231
rpoC765404p.Leu679Val0.308
rpoC765409c.2040T>C0.330
rpoC765421c.2052C>G0.319
rpoC765451c.2082C>G0.313
rpoC765452p.Ala695Ser0.313
rpoC765466c.2097C>T0.315
rpoC765478c.2109T>C0.315
rpoC765499c.2130C>G0.368
rpoC765508c.2139C>G0.356
rpoC765529c.2160C>T0.345
rpoC765541c.2172C>G0.295
rpoC765550c.2181C>T0.286
rpoC765553c.2184C>T0.271
rpoC765556c.2187G>C0.271
rpoC765580c.2211G>C0.304
rpoC765583c.2214G>C0.305
rpoC765613p.His748Gln0.302
rpoC765628c.2259G>C0.291
rpoC765631p.Asp754Glu0.291
rpoC765658c.2289C>T0.295
rpoC765700c.2331T>C0.326
rpoC765734c.2365T>C0.364
rpoC765739c.2370G>T0.369
rpoC765751c.2382C>G0.349
rpoC765753p.Asp795Ala0.372
rpoC765772c.2403C>G0.367
rpoC765784c.2415C>G0.330
rpoC765793c.2424C>G0.305
rpoC765796c.2427C>T0.289
rpoC765811c.2442T>G0.343
rpoC765826c.2457T>C0.370
rpoC765835c.2466C>T0.333
rpoC765886c.2517C>G0.308
rpoC765946c.2577C>T0.292
rpoC765958c.2589C>T0.283
rpoC765967c.2598C>T0.307
rpoC765982c.2613C>G0.295
rpoC765994c.2625A>T0.326
rpoC766010c.2641T>A0.259
rpoC766021c.2652G>C0.326
rpoC766027c.2658G>C0.341
rpoC766043p.Gln892Glu0.359
rpoC766054c.2685C>G0.371
rpoC766061p.Val898Leu0.382
rpoC766081c.2712T>C0.318
rpoC766082p.Ala905Gln0.313
rpoC766096c.2727G>C0.343
rpoC766097p.Leu910Val0.343
rpoC766105c.2736C>T0.352
rpoC766129c.2760C>G0.362
rpoC766141c.2772C>T0.325
rpoC766142c.2773C>T0.321
rpoC766147c.2778C>T0.325
rpoC766148p.Thr927Ala0.325
rpoC766178p.Ile937Val0.333
rpoC766258c.2889T>C0.333
rpoC766274p.Ala969Thr0.346
rpoC766280p.Ser971Gly0.364
rpoC766294c.2925C>T0.402
rpoC766297c.2928G>C0.402
rpoC766312c.2943T>G0.365
rpoC766321c.2952C>G0.374
rpoC766333c.2964G>C0.354
rpoC766345c.2976T>C0.343
rpoC766348c.2979A>G0.333
rpoC766357c.2988C>T0.283
rpoC766363c.2994G>C0.237
rpoC766366c.2997C>G0.223
rpoC766369c.3000C>G0.223
rpoC766381c.3012C>T0.259
rpoC766384c.3015A>G0.274
rpoC766390c.3021C>T0.276
rpoC766408c.3039C>T0.250
rpoC766426c.3057C>T0.265
rpoC766447c.3078T>C0.317
rpoC766480c.3111C>G0.270
rpoC766483c.3114G>C0.264
rpoC766484p.Val1039Ile0.264
rpoC766492c.3123T>C0.293
rpoC766522c.3153C>G0.247
rpoC766528c.3159T>C0.250
rpoC766531c.3162G>T0.250
rpoC766543c.3174C>T0.287
rpoC766549c.3180G>C0.295
rpoC766573c.3204T>C0.259
rpoC766583p.Gly1072Ser0.186
rpoC766588c.3219G>A0.190
rpoC766591c.3222A>G0.182
rpoC766594c.3225G>C0.188
rpoC766597c.3228C>G0.185
rpoC766607p.Ile1080Leu0.233
rpoC766645c.3276A>G0.309
rpoC766657c.3288A>G0.309
rpoC766672c.3303T>C0.286
rpoC766726c.3357T>C0.320
rpoC766738c.3369G>C0.326
rpoC766765c.3396A>C0.344
rpoC766774c.3405T>C0.306
rpoC766777c.3408C>T0.305
rpoC766801c.3432C>A0.260
rpoC766804c.3435A>G0.266
rpoC766861c.3492G>C0.348
rpoC766864c.3495G>C0.355
rpoC766882c.3513C>T0.356
rpoC766894c.3525T>C0.295
rpoC766895c.3526T>C0.289
rpoC766900c.3531T>C0.303
rpoC766918c.3549C>T0.387
rpoC766933c.3564A>G0.409
rpoC766945c.3576A>C0.368
rpoC766963c.3594T>C0.365
rpoC766978c.3609C>G0.341
rpoC766996c.3627C>T0.349
rpoC767009c.3640T>A0.295
rpoC767014c.3645G>C0.318
rpoC767035c.3666G>C0.364
rpoC767059c.3690T>G0.390
rpoC767098c.3729T>C0.375
rpoC767119c.3750A>G0.356
rpoC767134c.3765C>A0.349
rpoC767167c.3798C>G0.331
rpoC767180p.Ala1271Gln0.312
rpoC767191c.3822C>G0.280
rpoC767206c.3837C>G0.269
rpoC767209c.3840T>C0.275
rpoC767212c.3843G>C0.275
rpoC767221c.3852C>G0.311
rpoC767230c.3861G>C0.311
rpoC767233c.3864T>C0.267
rpoC767263c.3894T>C0.209
rpoC767264p.Ala1299Gln0.207
rpoC767278c.3909T>C0.233
rpoC767281c.3912C>G0.236
rpoC767284c.3915C>G0.241
rpsL781348c.-212C>G0.215
rpsL781353c.-207T>C0.217
rpsL781372c.-188T>C0.283
rpsL781373c.-187G>C0.297
rpsL781395c.-165T>C1.000
rpsL781571c.12C>T0.320
rpsL781595c.36T>C0.270
rpsL781598c.39G>C0.270
rpsL781605p.Ile16Val0.250
rpsL781608p.Ser17Ala0.241
rpsL781628c.69T>C0.295
rpsL781649c.90T>C0.312
rpsL781655c.96T>C0.329
rpsL781676c.117C>G0.359
rpsL781682c.123T>C0.374
rpsL781715c.156T>C0.377
rpsL781728c.169T>C0.369
rpsL781736c.177T>C0.374
rpsL781742c.183C>T0.365
rpsL781754c.195G>C0.346
rpsL781760c.201T>C0.350
rpsL781769c.210G>A0.333
rpsL781808c.249C>T0.276
rpsL781811c.252C>T0.264
rpsL781814c.255C>T0.277
rpsL781817c.258G>T0.322
rpsL781829c.270G>T0.360
rpsL781832c.273T>C0.357
rpsL781838c.279G>C0.356
rpsL781841c.282C>G0.356
rpsL781859c.300T>C0.359
rpsL781868c.309T>C0.389
rpsL781871c.312G>C0.389
rpsL781892c.333A>G0.361
rpsL781898c.339A>T0.326
rpsL781901c.342C>T0.345
rpsL781916c.357T>C0.349
rpsL781929p.Gly124Ser0.380
rplC800799c.-10G>C0.185
rplC800806c.-3G>C0.185
rplC800807c.-2C>T0.179
rplC800808c.-1A>C0.179
rplC800815c.7C>A0.178
rplC800820c.12G>A0.176
rplC800829c.21C>G0.222
rplC800844c.36T>C0.247
rplC800856c.48A>G0.263
rplC800865c.57A>G0.190
rplC800867p.Ser20Asn0.186
rplC800874c.66A>G0.219
rplC800877c.69A>C0.210
rplC800880c.72A>G0.197
rplC800889c.81C>G0.232
rplC800892c.84G>C0.231
rplC800904c.96G>C0.262
rplC800907c.99C>G0.262
rplC800916c.108A>G0.293
rplC800922c.114C>G0.290
rplC800928c.120C>T0.264
rplC800931c.123G>C0.264
rplC800937c.129A>G0.292
rplC800946c.138T>C0.289
rplC800949c.141T>C0.302
rplC800970c.162T>C0.307
rplC800982c.174C>T0.327
rplC800985c.177A>C0.323
rplC801004p.Leu66Val0.301
rplC801009c.201A>C0.276
rplC801019p.Thr71Ala0.286
rplC801027c.219C>G0.299
rplC801039c.231A>G0.267
rplC801045c.237A>G0.247
rplC801047p.Tyr80Phe0.247
rplC801054c.246G>C0.236
rplC801132c.324T>C0.208
rplC801136p.Ser110Ala0.208
rplC801147c.339T>C0.295
rplC801150c.342G>C0.338
rplC801156c.348T>C0.364
rplC801171c.363A>G0.350
rplC801174c.366T>C0.375
rplC801195c.387G>C0.419
rplC801207c.399C>T0.365
rplC801210c.402T>C0.370
rplC801213c.405G>A0.386
rplC801222c.414T>C0.426
rplC801246c.438C>G0.345
rplC801249c.441T>G0.339
rplC801252c.444G>C0.339
rplC801255c.447C>A0.328
rplC801267c.459A>C0.270
rplC801270c.462T>C0.254
rplC801276c.468G>C0.258
rplC801279c.471G>C0.266
rplC801282c.474G>C0.271
rplC801288c.480G>C0.288
rplC801309c.501C>G0.224
rplC801312c.504G>C0.224
rplC801321c.513C>T0.246
rplC801324c.516T>C0.243
rplC801339c.531T>C0.209
rplC801341p.Leu178Gln0.209
rplC801348c.540T>G0.235
rplC801357c.549T>C0.226
rplC801367p.Ala187Thr0.246
rplC801385c.577C>T0.288
rplC801396c.588T>C0.294
rplC801402c.594T>C0.269
rplC801405c.597T>C0.277
rplC801423c.615G>C0.179
rplC801426c.618C>G0.189
rplC801427p.Met207Val0.185
rplC801438c.630T>C0.176
rplC801442p.Ile212Val0.179
rplC801447c.639A>G0.167
embR1417019p.Cys110Tyr1.000
embR1417554c.-207C>G1.000
rrs1471923r.78t>c0.298
rrs1471934r.89a>g0.322
rrs1471969r.124t>c0.324
rrs1471970r.125g>a0.324
rrs1472044r.199g>t0.154
rrs1472061r.216a>t0.172
rrs1472075r.230a>g0.196
rrs1472108r.263c>t0.224
rrs1472969r.1124a>g0.339
rrs1472970r.1125c>g0.339
rrs1472977r.1132g>c0.316
rrs1472978r.1133t>c0.316
rrs1473104r.1259c>t0.354
rrs1473105r.1260g>a0.354
rrs1473123r.1278a>t0.300
rrs1473145r.1300c>t0.324
rrs1473166r.1321g>a0.329
rrs1473288r.1443c>t0.243
rrs1473290r.1445c>t0.239
rrs1473291r.1446g>t0.239
rrl1473569c.-89A>T0.320
rrl1473571c.-87C>T0.320
rrl1473668r.11c>t0.348
rrl1473752r.95g>t0.395
rrl1473756r.99g>a0.395
rrl1473758r.101g>t0.405
rrl1473806r.149c>t0.361
rrl1473813r.156c>t0.385
rrl1473839r.182g>t0.413
rrl1473877r.220g>a0.373
rrl1473898r.241c>t0.352
rrl1473899r.242a>c0.352
rrl1473943r.286g>t0.408
rrl1473944r.287g>a0.380
rrl1473966r.309t>c0.455
rrl1473971r.314g>t0.370
rrl1473981r.324g>t0.349
rrl1473995r.338g>t0.521
rrl1474001r.344c>t0.481
rrl1474009r.352a>g0.500
rrl1474012r.355c>t0.481
rrl1474036r.379g>a0.509
rrl1474040r.383g>a0.483
rrl1474054r.397t>c0.519
rrl1474093r.436g>t0.540
rrl1474099r.442g>a0.551
rrl1474103r.446a>t0.551
rrl1474111r.454t>c0.472
rrl1474140r.483c>t0.480
rrl1474151r.494c>t0.480
rrl1474181r.524c>t0.458
rrl1474249r.592g>t0.459
rrl1474282r.625g>a0.471
rrl1474290r.633ttttcctctccggagg>t0.484
rrl1474306r.649a>c0.370
rrl1474308r.651g>t0.345
rrl1474310r.653t>g0.345
rrl1474356r.699t>c0.526
rrl1474362r.705a>g0.526
rrl1474376r.719t>c0.486
rrl1474427r.770a>c0.148
rrl1474429r.772g>c0.148
rrl1474432r.775c>g0.148
rrl1474639r.982g>a0.388
rrl1474794r.1137c>t0.262
rrl1474812r.1155g>a0.396
rrl1474823r.1166c>t0.444
rrl1474831r.1174a>g0.478
rrl1474904r.1247g>a0.382
rrl1474956r.1299c>t0.352
rrl1474960r.1303c>g0.362
rrl1474963r.1306g>t0.350
rrl1474964r.1307t>a0.350
rrl1474965r.1308g>c0.350
rrl1474969r.1312g>a0.359
rrl1475006r.1349a>t0.426
rrl1475013r.1356g>a0.449
rrl1475061r.1404c>t0.348
rrl1475088r.1431a>t0.347
rrl1475199r.1542g>a0.306
rrl1475201r.1544g>a0.306
rrl1475206r.1549c>t0.289
rrl1475209r.1552g>c0.316
rrl1475213r.1556c>t0.324
rrl1475249r.1592t>c0.491
rrl1475252r.1595c>t0.510
rrl1475266r.1609t>c0.524
rrl1475267r.1610g>a0.512
rrl1475275r.1618c>t0.511
rrl1475276r.1619t>c0.511
rrl1475291r.1634a>c0.531
rrl1475315r.1658a>t0.528
rrl1475355r.1698c>t0.435
rrl1475369r.1712g>c0.370
rrl1475402r.1745c>t0.346
rrl1475409r.1752t>c0.367
rrl1475419r.1762c>t0.383
rrl1475429r.1772g>a0.327
rrl1475483r.1826c>t0.415
rrl1475505r.1848g>a0.500
rrl1475526r.1869c>a0.500
rrl1475599r.1942a>g0.422
rrl1475608r.1951t>c0.405
rrl1475638r.1981c>t0.388
rrl1475642r.1985t>c0.362
rrl1475657r.2000a>g0.353
rrl1475659r.2002g>t0.353
rrl1475758r.2101ac>a0.341
rrl1475763r.2106c>t0.279
rrl1475881r.2224t>c0.368
rrl1475988r.2331a>g0.471
rrl1476034r.2377c>a0.432
rrl1476045r.2388g>t0.444
rrl1476047r.2390g>t0.432
rrl1476048r.2391g>a0.432
rrl1476049r.2392c>t0.432
rrl1476086r.2429g>a0.400
rrl1476089r.2432t>c0.400
rrl1476095r.2438c>g0.375
rrl1476106r.2449a>t0.286
rrl1476115r.2458t>c0.375
rrl1476117r.2460g>c0.396
rrl1476214r.2557g>t0.320
rrl1476215r.2558c>t0.327
rrl1476224r.2567a>g0.304
rrl1476281r.2624t>c0.237
rrl1476297r.2640c>t0.222
rrl1476299r.2642c>t0.243
rrl1476583r.2926g>a0.289
rrl1476584r.2927c>t0.304
rrl1476597r.2940g>a0.269
rrl1476608r.2951c>g0.286
rrl1476628r.2971t>a0.265
rrl1476689r.3032a>t0.246
rrl1476690r.3033c>t0.246
rrl1476693r.3036g>a0.246
rrl1476695r.3038t>a0.269
rrl1476716r.3059a>c0.357
rrl1476726r.3069a>g0.343
rrl1476732r.3075t>c0.348
rrl1476746r.3089t>c0.350
rrl1476759r.3102t>c0.302
rrl1476770r.3113t>c0.275
rrl1476771r.3114g>a0.255
fabG11673481c.42A>C0.338
fabG11673499c.60T>C0.338
fabG11673505c.66A>C0.329
fabG11673535c.96A>G0.373
fabG11673538c.99G>A0.373
fabG11673547c.108T>C0.370
fabG11673574c.135C>G0.239
fabG11673580c.141T>C0.167
fabG11673583c.144A>G0.179
fabG11673589c.150A>G0.132
fabG11673633p.Ser65Asn0.204
fabG11673637p.Asp66Glu0.185
fabG11673640c.201C>G0.185
fabG11673646c.207T>C0.203
fabG11673657p.Thr73Lys0.186
fabG11673660p.Ala74Glu0.180
fabG11673664c.225A>C0.197
fabG11673667c.228A>G0.226
fabG11673710p.Leu91Ile0.287
fabG11673716p.Ala93Lys0.272
fabG11673724c.285A>G0.268
fabG11673730c.291C>G0.282
fabG11673733p.Met98Ile0.301
fabG11673748c.309A>G0.265
fabG11673749p.Lys104Arg0.275
fabG11673758p.Lys107Glu0.317
fabG11673787c.348G>C0.284
fabG11673796c.357G>T0.163
fabG11673799c.360T>C0.160
fabG11673802c.363A>G0.160
fabG11673805c.366G>C0.169
fabG11673808c.369A>C0.169
fabG11673811c.372G>A0.169
fabG11673871c.432C>T0.316
fabG11673895c.456C>T0.309
fabG11673901c.462A>G0.309
fabG11673905p.Ser156Ala0.290
fabG11673916c.477A>C0.301
fabG11673917p.Val160Leu0.301
fabG11673922c.483T>C0.305
fabG11673941p.Ala168Ser0.282
fabG11673946c.507C>G0.268
fabG11673955c.516G>C0.310
fabG11673961c.522A>C0.296
fabG11673985c.546C>G0.354
fabG11674006p.Asp189Glu0.429
fabG11674018c.579G>C0.411
fabG11674021c.582G>C0.400
fabG11674024c.585T>C0.349
fabG11674033c.594T>C0.355
fabG11674037p.Gln200Glu0.344
fabG11674042c.603G>T0.297
fabG11674049p.Gln204Asp0.250
fabG11674054c.615T>C0.211
fabG11674060c.621A>G0.194
fabG11674063c.624G>C0.190
fabG11674078c.639C>G0.164
fabG11674079p.Pro214Ala0.164
fabG11674096c.657G>C0.300
fabG11674098p.Val220Ala0.304
fabG11674114c.675T>G0.310
fabG11674123c.684T>C0.290
fabG11674126c.687G>C0.286
fabG11674132c.693T>C0.286
fabG11674136p.Ser233Ala0.286
fabG11674153c.714G>C0.288
fabG11674156c.717C>G0.284
fabG11674171c.732T>C0.281
inhA1674199c.-3C>G0.191
inhA1674205p.Thr2Ala0.191
inhA1674216c.15G>C0.182
inhA1674255c.54C>T0.233
inhA1674264c.63C>T0.233
inhA1674331c.130C>T0.121
inhA1674336c.135G>C0.127
inhA1674342c.141T>C0.130
inhA1674352p.Thr51Ala0.180
inhA1674368p.Ala56Glu0.140
inhA1674375c.174C>G0.133
inhA1674382p.Leu61Ile0.127
inhA1674480c.279T>C0.349
inhA1674486c.285T>C0.365
inhA1674489c.288G>T0.382
inhA1674537c.336C>G0.290
inhA1674542p.Ala114Glu0.339
inhA1674549c.348G>C0.328
inhA1674552c.351C>G0.304
inhA1674555c.354G>A0.300
inhA1674561c.360C>T0.303
inhA1674585c.384T>C0.205
inhA1674589p.Met130Leu0.200
inhA1674601p.Leu134Thr0.196
inhA1674618c.417C>T0.170
inhA1674624c.423A>C0.131
inhA1674660c.459G>C0.174
inhA1674669c.468G>C0.161
inhA1674690c.489C>G0.203
inhA1674702c.501G>A0.239
inhA1674703c.502T>C0.239
inhA1674708c.507G>A0.225
inhA1674718c.517A>C0.260
inhA1674738c.537C>G0.293
inhA1674741c.540C>T0.286
inhA1674746p.Tyr182Phe0.296
inhA1674756c.555T>C0.326
inhA1674774c.573A>G0.323
inhA1674780c.579T>G0.308
inhA1674795c.594G>C0.297
inhA1674801c.600T>C0.275
inhA1674816c.615T>G0.296
inhA1674840c.639C>G0.284
inhA1674846p.Ile215Met0.274
inhA1674858c.657G>A0.247
inhA1674879c.678T>C0.225
inhA1674882c.681G>C0.236
inhA1674903c.702T>C0.211
inhA1674904p.Ala235Pro0.217
inhA1674909c.708G>C0.234
inhA1674939c.738G>C0.172
inhA1674942c.741T>G0.167
inhA1674960c.759C>G0.151
inhA1674966c.765T>A0.137
inhA1674967p.Asp256Thr0.133
inhA1674978c.777C>T0.145
rpsA1833518c.-24C>A0.242
rpsA1833554p.Thr5Ala0.274
rpsA1833589c.48A>T0.313
rpsA1833595c.54T>G0.352
rpsA1833604c.63C>T0.322
rpsA1833667c.126C>G0.306
rpsA1833703c.162C>T0.309
rpsA1833724c.183C>G0.254
rpsA1833727c.186G>C0.246
rpsA1833745c.204G>C0.230
rpsA1833760c.219C>T0.250
rpsA1833793c.252C>T0.217
rpsA1833811c.270G>C0.197
rpsA1833841c.300C>G0.276
rpsA1833856c.315A>G0.324
rpsA1833871c.330G>A0.290
rpsA1833874c.333T>C0.279
rpsA1833940c.399C>G0.333
rpsA1833958c.417C>A0.306
rpsA1833979c.438T>C0.303
rpsA1833997c.456G>C0.357
rpsA1834000c.459G>C0.349
rpsA1834009c.468C>G0.370
rpsA1834012c.471G>C0.375
rpsA1834030c.489C>G0.435
rpsA1834051c.510G>A0.439
rpsA1834069c.528G>C0.408
rpsA1834099c.558C>G0.410
rpsA1834102c.561T>G0.368
rpsA1834105c.564C>G0.375
rpsA1834117c.576G>A0.338
rpsA1834144c.603G>A0.324
rpsA1834153c.612T>C0.185
rpsA1834154p.Asn205Gln0.185
rpsA1834157c.616T>C0.182
rpsA1834162c.621A>G0.182
rpsA1834165c.624A>G0.182
rpsA1834169p.Thr210Ala0.190
rpsA1834177c.636A>C0.329
rpsA1834186c.645C>G0.338
rpsA1834189c.648G>C0.347
rpsA1834192c.651C>G0.352
rpsA1834195c.654G>C0.365
rpsA1834222c.681T>C0.380
rpsA1834231c.690T>C0.392
rpsA1834240c.699T>C0.411
rpsA1834249c.708T>C0.304
rpsA1834252c.711C>G0.271
rpsA1834259c.718C>T0.250
rpsA1834262c.721T>A0.225
rpsA1834294c.753G>C0.312
rpsA1834303c.762T>C0.293
rpsA1834306c.765T>C0.317
rpsA1834348c.807T>C0.365
rpsA1834366c.825A>G0.356
rpsA1834396c.855G>C0.400
rpsA1834411c.870T>C0.430
rpsA1834417c.876G>C0.418
rpsA1834423c.882G>C0.421
rpsA1834435c.894G>C0.417
rpsA1834451c.910T>C0.418
rpsA1834456c.915T>G0.425
rpsA1834468c.927A>G0.429
rpsA1834474c.933C>G0.403
rpsA1834489c.948T>C0.379
rpsA1834528c.987T>C0.300
rpsA1834534c.993C>G0.299
rpsA1834540c.999G>A0.329
rpsA1834546c.1005T>C0.362
rpsA1834555c.1014T>C0.373
rpsA1834609c.1068T>C0.403
rpsA1834633c.1092A>G0.408
rpsA1834639c.1098T>C0.382
rpsA1834654c.1113G>A0.411
rpsA1834690c.1149T>C0.321
rpsA1834733p.Ala398Ser0.326
rpsA1834738c.1197A>G0.353
rpsA1834753c.1212T>C0.364
rpsA1834765c.1224A>G0.329
rpsA1834780c.1239A>G0.386
rpsA1834789c.1248T>C0.390
rpsA1834792c.1251G>C0.390
rpsA1834810c.1269C>G0.319
rpsA1834852c.1311C>T0.219
rpsA1834966c.1425A>G0.177
tlyA1917943p.Ala2Pro0.203
tlyA1917951c.12T>C0.256
tlyA1917953p.Ala5Val0.699
tlyA1917957c.18C>G0.301
tlyA1917972c.33A>G1.000
tlyA1917981c.42G>C0.310
tlyA1917990c.51G>C0.370
tlyA1917993c.54A>G0.369
tlyA1918002c.63A>G0.368
tlyA1918026c.87C>G0.345
tlyA1918029c.90C>G0.345
tlyA1918036p.Arg33Ser0.358
tlyA1918048p.Leu37Met0.375
tlyA1918057p.Val40Arg0.346
tlyA1918067p.Ala43Gly0.348
tlyA1918128c.189A>C0.173
tlyA1918137c.198A>G0.180
tlyA1918182c.243G>C0.250
tlyA1918191c.252G>T0.277
tlyA1918197c.258T>C0.269
tlyA1918206c.267G>C0.269
tlyA1918212c.273A>G0.221
tlyA1918218c.279C>G0.197
tlyA1918221c.282T>C0.197
tlyA1918224c.285G>T0.189
tlyA1918236c.297A>G0.191
tlyA1918266c.327G>C0.176
tlyA1918271p.Ala111Val0.186
tlyA1918278c.339C>G0.214
tlyA1918314c.375T>C0.145
tlyA1918317c.378T>G0.145
tlyA1918326c.387G>C0.153
tlyA1918330p.Leu131Val0.158
tlyA1918392c.453A>G0.322
tlyA1918476c.537A>C0.247
tlyA1918477p.Leu180Met0.250
tlyA1918497c.558G>A0.314
katG2154724p.Arg463Leu1.000
katG2155561p.Gly184Ala0.156
katG2155566c.546C>G0.171
katG2155581c.531G>T0.169
katG2155632c.480T>G0.167
katG2155637p.Leu159Ile0.171
katG2155641p.Lys157Asn0.167
katG2155661p.Val151Leu0.148
katG2155676c.436G>T0.176
katG2155686c.426G>A0.205
katG2155691c.421A>G0.211
katG2155695c.417G>C0.208
katG2155716c.396A>G0.173
katG2155722c.390C>A0.159
katG2155728c.384C>G0.155
katG2155766p.His116Phe0.132
katG2155785c.327A>G0.189
katG2155836c.276G>C0.155
katG2155847p.Pro89Asp0.125
kasA2518132c.18C>T1.000
kasA2518146p.Phe11Tyr0.224
kasA2518152p.Ser13Asn0.208
kasA2518162c.48G>A0.232
kasA2518174c.60A>G0.297
kasA2518190p.Ser26Ala0.314
kasA2518219c.105T>A0.301
kasA2518220c.106C>T0.301
kasA2518234c.120G>A0.280
kasA2518248p.Ala45Val0.278
kasA2518261p.Glu49Asp0.247
kasA2518265p.Val51Ile0.230
kasA2518396c.282A>C0.265
kasA2518405c.291C>G0.271
kasA2518426c.312T>C0.258
kasA2518429c.315A>C0.258
kasA2518439p.Ala109Ser0.163
kasA2518444c.330T>C0.178
kasA2518447c.333T>G0.214
kasA2518462c.348A>C0.259
kasA2518468c.354A>C0.244
kasA2518474c.360G>A0.239
kasA2518480c.366T>C0.207
kasA2518483c.369C>G0.219
kasA2518504c.390T>C0.250
kasA2518506p.Ala131Glu0.250
kasA2518519c.405G>C0.263
kasA2518528c.414C>G0.272
kasA2518534c.420G>C0.291
kasA2518561c.447T>C0.284
kasA2518574p.Ile154Val0.284
kasA2518579c.465T>C0.253
kasA2518588c.474T>G0.293
kasA2518591c.477G>C0.288
kasA2518609p.Met165Ile0.323
kasA2518612c.498C>T0.317
kasA2518624c.510C>G0.247
kasA2518627c.513T>C0.247
kasA2518633c.519G>C0.286
kasA2518642c.528A>G0.272
kasA2518651c.537C>G0.250
kasA2518663c.549T>C0.239
kasA2518671p.Val186Ala0.209
kasA2518678c.564C>T0.233
kasA2518687c.573C>T0.209
kasA2518688p.Val192Phe0.209
kasA2518705c.591T>G0.239
kasA2518711c.597A>G0.190
kasA2518714c.600A>T0.215
kasA2518732c.618C>G0.321
kasA2518765c.651G>C0.348
kasA2518768c.654C>T0.352
kasA2518783c.669T>C0.423
kasA2518789c.675G>C0.400
kasA2518792c.678C>G0.400
kasA2518795c.681C>G0.388
kasA2518825c.711T>C0.388
kasA2518843c.729T>G0.333
kasA2518846c.732G>C0.301
kasA2518853p.Leu247Ile0.280
kasA2518864c.750G>C0.256
kasA2518879c.765A>G0.269
kasA2518885c.771T>C0.253
kasA2518892p.Lys260Arg0.148
kasA2518898c.784T>C0.143
kasA2518906c.792A>G0.169
kasA2518910p.Leu266Met0.169
kasA2518921c.807T>C0.133
kasA2519029c.915C>T0.194
kasA2519050c.936C>G0.167
kasA2519056c.942G>A0.172
kasA2519062c.948T>G0.179
kasA2519068c.954C>T0.152
kasA2519072p.Ala320Thr0.164
kasA2519077c.963G>C0.175
ahpC2726564c.372C>G0.186
ahpC2726579c.387T>C0.268
ahpC2726582c.390G>C0.264
ahpC2726591c.399C>G0.271
ahpC2726593p.Val134Ala0.271
ahpC2726600c.408T>C0.341
ahpC2726612c.420C>G0.354
ahpC2726638p.Ala149Val0.358
ahpC2726645c.453C>G0.366
ahpC2726657c.465A>C0.378
ahpC2726660c.468C>T0.373
ahpC2726669p.Asp159Glu0.403
ahpC2726675c.483A>G0.412
ahpC2726681c.489A>C0.361
ahpC2726684c.492G>C0.352
ahpC2726693c.501C>A0.312
ahpC2726696c.504C>G0.284
ahpC2726717c.525A>G0.231
ahpC2726735c.543C>T0.171
ahpC2726747c.555A>G0.151
folC2746158c.1441A>G0.288
folC2746162c.1437C>G0.288
folC2746165c.1434A>G0.293
folC2746174c.1425T>G0.349
folC2746183c.1416A>G0.302
folC2746204c.1395C>G0.250
folC2746266p.Ser445Ala0.127
folC2746270c.1329G>C0.125
folC2746282c.1317A>G0.211
folC2746285c.1314A>G0.204
folC2746308p.Arg431Ser0.214
folC2746312c.1287C>G0.222
folC2746321c.1278T>C0.214
folC2746416p.Glu395Gln0.209
folC2746420c.1179T>G0.206
folC2746426c.1173C>G0.209
folC2746429c.1170G>A0.212
folC2746438c.1161C>G0.256
folC2746441c.1158G>A0.256
folC2746451p.Gly383Ala0.303
folC2746453c.1146C>G0.312
folC2746474c.1125C>G0.303
folC2746478p.Phe374Tyr0.307
folC2746480c.1119T>G0.303
folC2746483c.1116G>A0.299
folC2746504c.1095C>G0.185
folC2746510c.1089T>C0.167
folC2746516c.1083A>C0.175
folC2746521p.Ser360Ala0.192
folC2746525c.1074C>G0.185
folC2746531c.1068C>G0.254
folC2746555c.1044C>T0.268
folC2746561c.1038G>T0.226
folC2746564c.1035T>G0.218
folC2746594c.1005A>G0.141
folC2746599p.Thr334Ala0.147
folC2746609c.990A>G0.130
folC2746631p.Gly323Val0.162
folC2746642c.957A>G0.165
folC2746657c.942A>G0.146
folC2746666c.933G>C0.140
folC2746687c.912G>C0.151
folC2746693c.906C>G0.163
folC2746714c.885A>G0.240
folC2746728c.871A>G0.143
folC2746729c.870G>A0.147
folC2746734p.Ile289Val0.147
folC2746735c.864G>A0.145
folC2746738c.861G>C0.159
folC2746741c.858G>A0.133
folC2746744c.855A>C0.128
folC2746765c.834T>C0.247
folC2746771c.828T>C0.247
folC2746777c.822A>C0.240
folC2746785p.Val272Ile0.178
folC2746791p.Ile270Val0.141
folC2746795c.804T>A0.141
folC2746800p.Arg267Gly0.141
folC2746813c.786T>C0.235
folC2746816c.783G>C0.232
folC2746825c.774C>G0.216
folC2747032c.567T>G0.389
folC2747059c.540A>G0.447
folC2747062c.537T>G0.448
folC2747071c.528G>C0.449
folC2747083c.516C>G0.436
folC2747086c.513T>C0.426
folC2747089c.510C>G0.436
folC2747101c.498C>G0.430
folC2747107c.492C>G0.364
folC2747110c.489A>G0.359
folC2747113c.486G>T0.359
folC2747116c.483C>G0.362
folC2747134c.465G>C0.405
folC2747224c.375C>G0.118
folC2747239c.360A>G0.151
folC2747245c.354C>G0.143
folC2747265p.Gly112Ser0.202
folC2747275c.324A>G0.229
folC2747284c.315C>G0.200
folC2747289p.Pro104Ala0.205
folC2747290c.309T>C0.208
folC2747293c.306C>T0.228
folC2747302c.297T>C0.295
folC2747314c.285T>G0.287
folC2747317c.282G>C0.295
folC2747343p.Val86Ile0.333
folC2747355p.Val82Ile0.326
folC2747359c.240G>C0.302
folC2747371c.228G>C0.330
folC2747392p.Ile69Met0.138
folC2747439p.Met54Leu0.159
folC2747467p.Asp44Glu0.133
folC2747475p.Arg42Lys0.137
folC2747491c.108T>C0.147
folC2747497c.102G>C0.123
ribD2987069c.231T>C0.147
ribD2987090c.252C>T0.157
ribD2987092p.Val85Ala0.155
ribD2987105c.267C>G0.152
ribD2987108c.270T>C0.147
ribD2987114c.276C>T0.135
thyX3067210c.736A>G0.268
thyX3067223c.723C>G0.286
thyX3067229c.717G>C0.301
thyX3067249p.Thr233Ser0.247
thyX3067252p.Val232Ile0.254
thyX3067277c.669G>C0.236
thyX3067284p.Ala221Gly0.169
thyX3067288p.Ala220Ser0.163
thyX3067316c.630T>C0.289
thyX3067349c.597C>G0.350
thyX3067355c.591T>C0.347
thyX3067367c.579C>G0.384
thyX3067373c.573G>C0.357
thyX3067406c.540T>C0.355
thyX3067412c.534G>T0.342
thyX3067427c.519C>G0.351
thyX3067439c.507T>C0.313
thyX3067457c.489G>C0.299
thyX3067462c.484G>A0.278
thyX3067465p.Ile161Val0.268
thyX3067466c.480C>G0.268
thyX3067470p.Asn159Ser0.260
thyX3067478c.468G>A0.286
thyX3067499c.447C>T0.312
thyX3067504p.Ala148Thr0.301
thyX3067515p.Ser144Thr0.303
thyX3067520c.426G>C0.290
thyX3067616c.330G>C0.221
thyX3067619c.327T>G0.217
thyX3067625c.321G>A0.230
thyX3067631c.315G>C0.225
thyX3067634c.312G>C0.231
thyX3067643c.303G>A0.240
thyX3067652c.294A>G0.213
thyX3067658c.288G>A0.260
thyX3067661c.285G>C0.257
thyX3067688c.258C>G0.263
thyX3067694c.252C>G0.230
thyX3067706c.240G>A0.222
thyX3067709c.237C>G0.222
thyX3067718c.228G>C0.233
thyX3067721c.225A>G0.209
thyX3067727c.219T>G0.212
thyX3067736c.210G>A0.190
thyX3067739c.207A>G0.179
thyX3067742c.204T>C0.182
thyX3067762p.Arg62Lys0.203
thyX3067765p.Leu61Ile0.203
thyX3067781c.165G>C0.160
thyX3067793c.153A>G0.134
thyX3067802c.144G>C0.136
thyX3067814c.132A>G0.203
thyX3067820c.126G>A0.224
thyX3067835c.111C>T0.235
thyX3067850c.96T>A0.236
thyX3067870p.Thr26Asp0.278
thyX3067874c.72G>C0.274
thyX3067883c.63G>C0.270
thyX3067886c.60T>G0.284
thyX3067889c.57G>C0.266
thyX3067935p.Thr4Ile0.221
thyA3073839c.633A>G0.156
thyA3073860c.612G>C0.230
thyA3073866c.606G>C0.235
thyA3073874p.Ile200Val0.240
thyA3073889p.Ser195Ala0.267
thyA3073892c.580A>G0.272
thyA3073905c.567G>C0.297
thyA3073917c.555G>C0.316
thyA3073920c.552G>C0.320
thyA3073925c.547A>G0.316
thyA3073929c.543A>G0.309
thyA3073953c.519A>G0.360
thyA3073958c.514G>A0.348
thyA3073959c.513A>G0.354
thyA3073977c.495T>C0.342
thyA3073989c.483A>G0.371
thyA3074001c.471G>C0.323
thyA3074004c.468A>G0.311
thyA3074010c.462G>C0.337
thyA3074031c.441A>G0.394
thyA3074037c.435G>C0.392
thyA3074053p.Arg140Gln0.354
thyA3074057p.Glu139Pro0.327
thyA3074061c.411T>C0.330
thyA3074076c.396G>C0.364
thyA3074097c.375G>C0.312
thyA3074100c.372A>G0.315
thyA3074103c.369G>C0.315
thyA3074106c.366A>G0.337
thyA3074120c.352A>G0.315
thyA3074121p.Asp117Glu0.315
thyA3074127c.345C>G0.326
thyA3074130c.342C>G0.333
thyA3074154c.318A>G0.267
thyA3074157c.315G>A0.231
thyA3074160c.312T>G0.231
thyA3074165p.Ala103Thr0.250
thyA3074172c.300C>G0.301
thyA3074181c.291T>C0.333
thyA3074187c.285A>G0.341
thyA3074193c.279G>T0.325
thyA3074205p.Glu89Asp0.315
thyA3074214c.258A>G0.340
thyA3074217c.255A>G0.344
thyA3074244c.228T>C0.333
thyA3074252p.Glu74Gln0.321
thyA3074262c.210A>G0.301
thyA3074267p.Ile69Val0.289
thyA3074268c.204A>G0.289
thyA3074274c.198A>G0.312
thyA3074334c.138A>G0.214
thyA3074349c.123A>G0.224
thyA3074357p.Ser39Ala0.182
thyA3074360c.112C>G0.200
thyA3074361c.111A>G0.185
thyA3074372p.Met34Leu0.299
thyA3074379c.93G>A0.324
ald3086788c.-32T>C1.000
ald3087686c.867C>G0.155
ald3087699p.Leu294Val0.197
ald3087704c.885T>C0.190
fbiA3640291c.-252T>C0.185
fbiA3640307c.-236C>A0.183
fbiA3640347c.-196A>G0.283
fbiA3640349c.-194A>G0.283
fbiA3640350c.-193C>T0.283
fbiA3640365c.-178C>G0.337
fbiA3640378c.-165A>T0.319
fbiA3640562p.Ala7Val0.213
fbiA3640569c.27A>G0.211
fbiA3640572c.30C>T0.211
fbiA3640593c.51C>G0.203
fbiA3640707c.165G>A0.139
fbiA3640713c.171T>A0.155
fbiA3640810p.Gln90Glu0.125
fbiA3640816c.274C>T0.151
fbiA3640820p.Val93Ala0.164
fbiA3640827c.285T>C0.143
fbiA3640830c.288C>G0.154
fbiA3640839c.297C>G0.190
fbiA3640848c.306C>T0.174
fbiA3640850p.Glu103Gly0.169
fbiA3640857c.315G>C0.197
fbiA3640863c.321C>G0.225
fbiA3640866c.324T>C0.231
fbiA3640871p.Ala110Gly0.237
fbiA3640878c.336T>C0.305
fbiA3640899c.357G>C0.264
fbiA3640900p.Gln120Asn0.268
fbiA3640911c.369C>T0.250
fbiA3640917c.375G>C0.230
fbiA3640920c.378A>G0.224
fbiA3641073c.531T>G0.174
fbiA3641085c.543G>C0.153
fbiA3641097c.555T>C0.147
fbiA3641100c.558T>G0.145
fbiA3641103c.561T>C0.143
fbiA3641164p.Ile208Val0.167
fbiA3641170p.Met210Leu0.197
fbiA3641184c.642T>G0.173
fbiA3641187c.645T>C0.169
fbiA3641196c.654C>G0.149
fbiA3641200p.Ile220Val0.157
fbiA3641286c.744C>T0.223
fbiA3641288p.Glu249Gly0.228
alr3840215c.1206A>G0.242
alr3840230c.1191A>C0.225
alr3840233c.1188T>C0.229
alr3840236c.1185T>G0.229
alr3840239c.1182C>G0.236
alr3840248c.1173G>C0.243
alr3840251c.1170C>G0.243
alr3840254c.1167T>C0.250
alr3840274p.Val383Leu0.289
alr3840275c.1146A>C0.275
alr3840278c.1143A>G0.272
alr3840293c.1128A>C0.230
alr3840296c.1125C>G0.230
alr3840371c.1050C>G0.217
alr3840382p.Met347Val0.247
alr3840407c.1014C>G0.203
alr3840410c.1011A>G0.177
alr3840413c.1008G>C0.165
alr3840418p.Cys335Arg0.148
alr3840419c.1002T>C0.146
alr3840422p.Arg333Ser0.148
alr3840436c.985G>A0.306
alr3840443c.978C>G0.302
alr3840469p.Val318Ile0.326
alr3840476c.945T>G0.330
alr3840482c.939A>G0.337
alr3840487p.Ile312Val0.323
alr3840500c.921C>G0.309
alr3840503c.918A>G0.301
alr3840516p.Pro302Gln0.179
alr3840522p.Ile300Thr0.188
alr3840527c.894T>G0.192
alr3840533c.888C>G0.217
alr3840536c.885A>G0.227
alr3840539c.882C>G0.234
alr3840547p.Gly292Ser0.263
alr3840557c.864A>G0.232
alr3840560c.861A>G0.222
alr3840944c.477A>G0.221
alr3840959c.462C>G0.259
alr3840962c.459C>G0.287
alr3840974c.447G>T0.308
alr3840980c.441C>G0.307
alr3840987p.Val145Ala0.318
alr3840994p.His143Asp0.330
alr3840997p.Leu142Val0.326
alr3841001p.Glu140Asp0.326
alr3841010c.411T>C0.326
alr3841018p.Leu135Glu0.311
alr3841028c.393C>G0.363
alr3841033p.Val130Ile0.370
alr3841079c.342A>G0.319
alr3841094c.327C>T0.247
alr3841097c.324C>G0.250
alr3841100c.321T>C0.243
alr3841106c.315A>G0.247
alr3841112c.309A>G0.194
alr3841115c.306A>C0.194
alr3841127c.294T>C0.143
alr3841130c.291C>G0.143
alr3841137p.Asp95Ala0.150
alr3841141p.Val94Ile0.138
alr3841652c.-232A>T0.243
alr3841654c.-234A>C0.254
alr3841662c.-242A>G0.243
alr3841663c.-243G>A0.241
panD4043867p.Gly139Arg0.140
panD4043872p.Gly137Val0.143
panD4043876p.Leu136Ile0.138
panD4043883c.399G>A0.127
panD4043903p.Asn127Asp0.116
panD4043905p.Glu126Ala0.116
panD4043913c.369A>G0.260
panD4043916c.366T>G0.274
panD4043933p.Met117Leu0.257
panD4043944p.Lys113Arg0.211
panD4043951p.Tyr111Asp0.187
panD4043952c.330A>G0.187
panD4043961c.321A>G0.304
panD4043964c.318C>G0.304
panD4044036c.246C>G0.133
panD4044042c.240A>G0.132
panD4044050c.232C>G0.128
panD4044051c.231G>A0.130
panD4044057c.225G>T0.195
panD4044072c.210G>T0.274
panD4044075c.207A>G0.274
panD4044081c.201A>C0.282
panD4044120c.162T>C0.392
panD4044123c.159A>G0.396
panD4044126c.156A>G0.417
panD4044150c.132T>C0.340
panD4044162c.120T>C0.319
panD4044165c.117C>G0.319
panD4044174c.108G>C0.316
panD4044177c.105G>C0.320
panD4044188c.94A>G0.263
panD4044189c.93G>A0.263
panD4044195c.87A>G0.324
panD4044228c.54G>C0.250
panD4044237c.45C>G0.237
panD4044240c.42C>G0.222
panD4044246c.36G>C0.295
panD4044264c.18C>G0.333
panD4044278c.4A>G0.325
embC4239994c.132C>G0.143
embC4240006c.144A>G0.133
embC4240012c.150G>T0.167
embC4240019p.Asn53Asp0.180
embC4240033c.171G>C0.217
embC4240048c.186C>G0.246
embC4240051c.189A>G0.246
embC4240060c.198G>C0.267
embC4240065p.Ala68Gly0.274
embC4240069c.207T>C0.263
embC4240075p.Glu71Asp0.282
embC4240078c.216A>C0.295
embC4240087c.225T>C0.310
embC4240096c.234G>C0.300
embC4240105c.243C>T0.330
embC4240123c.261C>G0.333
embC4240127p.Gln89Asp0.347
embC4240142c.280C>T0.287
embC4240151p.Ser97Pro0.179
embC4240160p.Thr100Ala0.179
embC4240183c.321A>G0.333
embC4240204c.342T>C0.280
embC4240244p.Asp128Asn0.179
embC4240258c.396T>G0.205
embC4240267c.405T>C0.195
embC4240270c.408T>C0.195
embC4240277p.Leu139Val0.229
embC4240282c.420C>G0.244
embC4240288c.426C>G0.253
embC4240297c.435T>C0.207
embC4240298p.Gln146Glu0.205
embC4240307p.Gly149Ser0.207
embC4240313p.Thr151Ala0.210
embC4240318c.456T>C0.231
embC4240330c.468A>C0.211
embC4240348p.Asp162Glu0.157
embC4240349p.Arg163Lys0.157
embC4240355p.Ala165Thr0.159
embC4240375c.513G>C0.246
embC4240376p.Val172Thr0.246
embC4240393c.531T>C0.234
embC4240399c.537C>T0.210
embC4240405c.543T>C0.188
embC4240406p.Ala182Ser0.190
embC4240420c.558T>C0.153
embC4240424p.Arg188Lys0.145
embC4240444c.582C>G0.325
embC4240462c.600G>C0.277
embC4240543c.681G>C0.286
embC4240561c.699C>G0.305
embC4240570c.708C>G0.269
embC4240574p.Val238Leu0.273
embC4240578p.Ala239Val0.263
embC4240582c.720C>G0.253
embC4240587p.Gly242Ala0.247
embC4240600c.738G>C0.326
embC4240615c.753G>C0.315
embC4240624c.762C>A0.303
embC4240632p.Met257Thr0.269
embC4240642c.780G>C0.340
embC4240645c.783G>C0.340
embC4240654c.792C>G0.312
embC4240657c.795G>C0.312
embC4240660c.798C>G0.327
embC4240671p.Thr270Ile1.000
embC4240678c.816T>G0.337
embC4240685p.Thr275Ala0.301
embC4240693c.831T>G0.330
embC4240698p.Ala279Gly0.333
embC4240726c.864G>C0.404
embC4240735c.873C>G0.395
embC4240768c.906G>C0.354
embC4240771c.909G>C0.347
embC4240780c.918T>C0.340
embC4240783c.921G>C0.337
embC4240789c.927T>C0.337
embC4240819c.957A>G0.330
embC4240825c.963G>A0.330
embC4240831c.969T>G0.309
embC4240867c.1005T>C0.153
embC4240870c.1008T>C0.146
embC4240873c.1011C>G0.149
embC4240879c.1017G>C0.139
embC4240880p.Ala340Thr0.139
embC4240885c.1023T>C0.141
embC4240886p.Ile342Val0.143
embC4240897c.1035C>G0.159
embC4240898c.1036C>T0.161
embC4240911p.Ala350Val0.264
embC4240921c.1059C>G0.256
embC4240924c.1062C>G0.260
embC4240936c.1074A>G0.256
embC4240945c.1083T>C0.200
embC4240954p.Ile364Met0.226
embC4240966c.1104G>T0.214
embC4240969c.1107C>T0.200
embC4240990c.1128A>C0.149
embC4240993c.1131G>C0.152
embC4241002c.1140G>C0.205
embC4241005c.1143G>C0.205
embC4241017c.1155T>C0.227
embC4241023c.1161T>C0.239
embC4241030c.1168C>T0.247
embC4241038c.1176G>C0.275
embC4241042p.Asn394Asp0.684
embC4241050c.1188T>G0.330
embC4241104c.1242G>A0.341
embC4241107c.1245G>C0.289
embC4241137c.1275G>C0.309
embC4241140c.1278A>G0.302
embC4241158c.1296T>C0.326
embC4241161c.1299C>G0.321
embC4241162c.1300T>C0.321
embC4241203c.1341T>C0.303
embC4241230c.1368A>G0.364
embC4241233c.1371G>A0.358
embC4241245c.1383C>T0.323
embC4241248c.1386G>C0.288
embC4241251c.1389T>C0.288
embC4241256p.Arg465Thr0.264
embC4241266c.1404C>T0.167
embC4241268p.Val469Ala0.162
embC4241275c.1413A>G0.138
embC4241281c.1419G>A0.138
embC4241284c.1422G>C0.138
embC4241290p.Ile476Met0.143
embC4241299c.1437G>T0.293
embC4241319p.Pro486Leu0.274
embC4241361p.Asn500Ser0.167
embC4241363p.Leu501Met0.165
embC4241374c.1512T>G0.233
embC4241380c.1518A>C0.260
embC4241383c.1521G>C0.250
embC4241394p.Lys511Ser0.247
embC4241413c.1551C>T0.221
embC4241443c.1581C>G0.217
embC4241449c.1587C>G0.213
embC4241453p.Ile531Val0.198
embC4241458c.1596C>G0.212
embC4241479c.1617C>G0.179
embC4241480c.1618T>C0.171
embC4241485c.1623G>T0.158
embC4241488c.1626G>C0.152
embC4241496p.Ala545Gly0.140
embC4241500c.1638A>C0.133
embC4241501p.Ser547Thr0.133
embC4241518c.1656A>G0.188
embC4241521c.1659T>C0.186
embC4241530c.1668C>G0.200
embC4241560c.1698C>G0.205
embC4241567p.Ile569Val0.200
embC4241578c.1716G>C0.220
embC4241584c.1722T>C0.182
embC4241591p.Leu577Ala0.165
embC4241611c.1749G>C0.186
embC4241614c.1752A>C0.198
embC4241617c.1755G>A0.193
embC4241626c.1764T>C0.224
embC4241644c.1782G>C0.256
embC4241648c.1786T>C0.256
embC4241656c.1794G>A0.207
embC4241657p.Ser599Pro0.209
embC4241665c.1803G>C0.205
embC4241671c.1809T>G0.207
embC4241683c.1821G>C0.175
embC4241704c.1842C>G0.181
embC4241713c.1851G>C0.198
embC4241727p.Phe622Tyr0.185
embC4241734c.1872C>G0.167
embC4241747p.Val629Leu0.125
embC4241750p.Leu630Val0.130
embC4241755c.1893C>G0.127
embC4241756c.1894C>T0.128
embC4241770c.1908T>C0.276
embC4241791c.1929G>C0.277
embC4241794c.1932C>G0.253
embC4241797c.1935C>T0.250
embC4241809c.1947A>C0.235
embC4242112c.2250G>A0.147
embC4242121c.2259A>G0.200
embC4242138p.Leu759Gln0.156
embC4242142p.Asp760Glu0.158
embC4242151c.2289A>C0.175
embC4242196c.2334A>C0.145
embC4242197p.Ala779Thr0.145
embC4242208c.2346T>G0.260
embC4242213p.Ala784Gly0.284
embC4242220c.2358A>G0.287
embC4242229c.2367C>A0.282
embC4242244c.2382C>G0.262
embC4242245p.Thr795Arg0.275
embC4242384p.Tyr841Phe0.169
embC4242391c.2529G>T0.188
embC4242397c.2535G>C0.224
embC4242403c.2541T>C0.228
embC4242406c.2544A>G0.232
embC4242415c.2553G>C0.232
embC4242519p.Thr886Ser0.207
embC4242523c.2661G>C0.198
embC4242532c.2670A>C0.196
embC4242539p.Ser893Pro0.186
embC4242552p.Arg897Gln0.193
embC4242554p.Leu898Val0.195
embC4242574p.Glu904Asp0.264
embC4242577c.2715A>G0.264
embC4242585p.Ala908Gly0.239
embC4242594p.His911Pro0.172
embC4242598c.2736T>C0.143
embC4242601c.2739G>T0.137
embC4242605p.Met915Phe0.152
embC4242608p.Glu916Gln0.139
embC4242622c.2760C>G0.200
embC4242625c.2763T>G0.213
embC4242628c.2766C>G0.239
embC4242629p.Ala923Ser0.239
embC4242643c.2781C>T0.740
embC4242653p.Ala931Leu0.133
embC4242658c.2796A>G0.145
embC4242664c.2802C>G0.140
embC4242667c.2805C>G0.143
embC4242677p.Thr939Ser0.138
embC4242695c.2833T>C0.156
embA4243222c.-11C>G0.183
embA4243250p.Asn6Lys0.159
embA4243848p.Val206Met1.000
embA4244669c.1437G>C0.225
embA4244671p.Ala480Gly0.222
embA4244681c.1449A>C0.244
embA4244726c.1494C>T0.239
embA4244728p.Phe499Trp0.230
embA4244885c.1653A>G0.127
embA4244886c.1654C>T0.127
embA4244945c.1713C>G0.256
embA4244948c.1716G>C0.264
embA4244960c.1728A>G0.283
embA4244980p.Val583Ala0.281
embA4244982c.1750T>C0.275
embA4244987c.1755T>C0.250
embA4244993c.1761C>G0.244
embA4245059c.1827G>C0.209
embA4245060c.1828T>C0.209
embA4245078p.Trp616Val0.284
embA4245083c.1851A>G0.297
embA4245089c.1857G>C0.291
embA4245101c.1869G>C0.333
embA4245125c.1893G>A0.398
embA4245137c.1905T>C0.421
embA4245149c.1917C>G0.411
embA4245153p.Ile641Val0.394
embA4245183c.1951C>T0.360
embA4245186p.Thr652Ala0.337
embA4245198p.Leu656Ala0.236
embA4245206c.1974A>C0.239
embA4245207c.1975T>C0.239
embA4245215c.1983A>C0.276
embA4245222p.Tyr664Gln0.284
embA4245239c.2007C>T0.316
embA4245257c.2025A>G0.234
embA4245263c.2031A>G0.176
embA4245431c.2199T>C0.154
embA4245434c.2202G>C0.153
embA4245470c.2238T>C0.300
embA4245485c.2253A>G0.206
embA4245490p.Val753Ala0.202
embA4245494c.2262G>C0.202
embA4245497c.2265C>G0.202
embA4245501p.Ala757Thr0.202
embA4245509c.2277A>G0.234
embA4245518c.2286A>C0.250
embA4245531p.Ile767Val0.225
embA4245535p.Ser768Asn0.235
embA4245539c.2307C>G0.229
embA4245557p.Glu775Asp0.146
embA4245569p.Glu779Asp0.147
embA4245641c.2409C>T0.250
embA4245645p.Ala805Thr0.247
embA4245650p.Ile806Met0.264
embA4245668c.2436C>G0.279
embA4245674c.2442A>C0.287
embA4245683c.2451C>A0.303
embA4245692c.2460G>A0.290
embA4245693p.Ile821Val0.287
embA4245710c.2478G>C0.302
embA4245726c.2494T>C0.300
embA4245731c.2499C>T0.300
embA4245737c.2505A>C0.275
embA4245740c.2508T>C0.275
embA4245743c.2511C>G0.272
embA4245764c.2532G>C0.321
embA4245771p.Asn847Ser0.259
embA4245785c.2553G>C0.217
embA4245788c.2556C>G0.220
embA4245797c.2565C>G0.243
embA4245807c.2575T>C0.219
embA4245815c.2583C>G0.176
embA4245818c.2586C>T0.185
embA4245969p.Pro913Ser1.000
embA4246031c.2799G>A0.215
embA4246041p.Asp937Asn0.218
embA4246049c.2817G>C0.205
embA4246055c.2823T>C0.222
embA4246064c.2832T>C0.234
embA4246070c.2838G>C0.197
embA4246250c.3018G>C0.227
embA4246259c.3027G>C0.234
embA4246262c.3030C>T0.242
embB4246652c.139C>T0.219
embB4246882c.369G>C0.206
embB4247050c.537C>G0.464
embB4247059c.546C>G0.462
embB4247062c.549G>A0.478
embB4247068c.555T>C0.465
embB4247091p.Thr193Ser0.403
embB4247098c.585C>G0.293
embB4247101c.588G>C0.267
embB4247105p.Pro198Ala0.233
embB4247110c.597G>T0.226
embB4247114p.Ala201Gln0.206
embB4247117p.Val202Leu0.206
embB4247317c.804G>C0.165
embB4247326c.813A>G0.212
embB4247328p.Ser272Asn0.214
embB4247338c.825C>G0.242
embB4247348p.Thr279Ala0.259
embB4247355p.Ala281Val0.129
embB4247367p.Phe285Ser0.126
embB4247375p.Leu288Val0.232
embB4247380c.867C>G0.225
embB4247386c.873T>C0.248
embB4247389c.876C>G0.248
embB4247395c.882C>G0.270
embB4247401c.888T>C0.283
embB4247437c.924A>G0.352
embB4247440c.927C>G0.330
embB4247446c.933C>T0.330
embB4247464c.951C>G0.336
embB4247470c.957T>C0.342
embB4247485c.972C>T0.340
embB4247488c.975C>T0.343
embB4247491c.978G>C0.349
embB4247512c.999T>C0.345
embB4247539c.1026T>C0.260
embB4247542c.1029C>G0.253
embB4247544p.Ser344Thr0.255
embB4247554c.1041T>C0.267
embB4247566c.1053C>G0.202
embB4247567c.1054C>T0.202
embB4247572c.1059A>G0.200
embB4247579p.Ala356Ile0.170
embB4247608c.1095G>C0.155
embB4247614c.1101T>G0.147
embB4247646p.Glu378Ala1.000
embB4247785c.1272G>C0.148
embB4247800c.1287A>C0.158
embB4247803c.1290G>C0.150
embB4247806c.1293G>C0.150
embB4247819p.Val436Ile0.149
embB4247827c.1314C>G0.164
embB4247830c.1317A>C0.164
embB4247836c.1323A>C0.175
embB4247842c.1329T>C0.164
embB4247845c.1332G>C0.175
embB4247857c.1344C>G0.186
embB4247858c.1345C>T0.186
embB4247869c.1356G>C0.192
embB4247872c.1359C>A0.203
embB4247881c.1368G>C0.188
embB4247899p.Met462Ile0.159
embB4247920c.1407T>C0.149
embB4247938c.1425G>C0.237
embB4247940p.Leu476Trp0.235
embB4247951p.Ser480Ala0.247
embB4247974c.1461C>G0.236
embB4247986c.1473C>G0.244
embB4248001c.1488C>T0.250
embB4248007c.1494C>G0.260
embB4248008c.1495C>T0.250
embB4248035p.Val508Ile0.222
embB4248064c.1551G>C0.153
embB4248070c.1557T>C0.163
embB4248085c.1572T>C0.233
embB4248088c.1575C>T0.235
embB4248097c.1584C>G0.256
embB4248106c.1593C>G0.244
embB4248115c.1602C>T0.245
embB4248118c.1605T>C0.240
embB4248127c.1614G>T0.243
embB4248130c.1617G>C0.260
embB4248142c.1629T>C0.253
embB4248143c.1630T>C0.253
embB4248149p.Thr546Ala0.281
embB4248157c.1644A>G0.281
embB4248163c.1650G>C0.282
embB4248172c.1659G>C0.296
embB4248175c.1662G>C0.279
embB4248178c.1665C>T0.287
embB4248206p.Ser565Gly0.264
embB4248211c.1698G>T0.264
embB4248214c.1701C>G0.282
embB4248220c.1707A>G0.333
embB4248226c.1713G>C0.338
embB4248277c.1764G>C0.380
embB4248316c.1803C>G0.343
embB4248319c.1806A>G0.338
embB4248322c.1809G>A0.306
embB4248668p.Val719Ile0.220
embB4248673c.2160G>C0.222
embB4248676c.2163C>G0.222
embB4248697c.2184A>C0.279
embB4248706c.2193G>C0.246
embB4248720p.Gly736Ala0.157
embB4248725p.Ser738Ala0.132
embB4248757c.2244A>G0.296
embB4248772c.2259A>G0.318
embB4248856c.2343T>C0.128
embB4248859c.2346A>T0.128
embB4249117c.2604G>C0.118
embB4249120c.2607C>T0.129
embB4249126c.2613G>A0.129
embB4249129c.2616T>C0.127
embB4249138c.2625C>G0.250
embB4249158p.Lys882Thr0.227
embB4249175p.Val888Ile0.233
embB4249342c.2829C>G0.122
embB4249351c.2838C>T0.139
embB4249360c.2847G>T0.136
embB4249369c.2856T>C0.138
embB4249387p.Glu958Asp0.167
embB4249400p.Val963Leu0.179
embB4249411c.2898G>A0.147
embB4249458p.Gln982Arg0.141
embB4249466c.2953C>T0.325
embB4249469p.Leu986Met0.329
embB4249486c.2973T>A0.292
embB4249487c.2974T>C0.295
embB4249492c.2979C>G0.293
embB4249520p.Ala1003Ser0.253
embB4249525c.3012T>C0.264
embB4249529p.Ile1006Val0.253
embB4249532p.Ala1007Thr0.253
embB4249537p.Glu1008Asp0.255
embB4249544p.Lys1011Glu0.289
embB4249558c.3045A>C0.292
embB4249568p.Ser1019Asn0.197
embB4249573c.3060T>C0.183
embB4249581p.Leu1023Gln0.192
embB4249594c.3081G>C0.145
embB4249598p.Glu1029Gln0.139
embB4249607p.Thr1032Val0.136
embB4249624c.3111C>G0.191
embB4249627c.3114G>C0.200
embB4249648c.3135G>C0.164
embB4249686p.Ala1058Gly0.195
embB4249693c.3180T>C0.195
embB4249699c.3186T>A0.203
embB4249702c.3189C>G0.213
ethA4326280c.1194C>G0.123
ethA4327387c.87G>T0.149
ethA4327396c.78A>G0.156
ethA4327399p.Asp25Glu0.162
ethA4327423c.51G>C0.172
ethA4327426c.48A>G0.161
ethA4327435c.39T>G0.157
ethA4327438c.36A>G0.155
ethA4327444c.30C>G0.159
ethA4327452p.Val8Leu0.153
ethA4327453c.21A>G0.153
ethA4327468c.6G>A0.160
ethR4327674c.126G>C0.232
ethR4327680c.132T>C0.205
ethR4327686c.138G>C0.205
ethR4327695c.147T>C0.210
ethR4327707c.159C>T0.236
ethR4327713c.165T>C0.217
ethR4327714p.Ile56Leu0.217
ethR4327719c.171G>C0.200
ethR4327720c.172A>C0.203
ethR4327755p.Glu69Asp0.239
ethR4327767c.219G>C0.232
ethR4327862p.Thr105Ile0.136
ethR4327879p.Phe111Val0.185
ethR4327887c.339A>C0.168
gid4407588c.615T>C1.000
gid4407603c.600C>T0.240
gid4407609c.594C>G0.250
gid4407652p.Val184Ala0.287
gid4407654c.549C>G0.287
gid4407668p.Ile179Ala0.227
gid4407873c.330C>A1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;