TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5dd7f6a160db9
Sample: 5dd7f6a160db9

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Summary
ID: 5dd7f6a160db9
Date: Fri Nov 22 15:01:56 2019
Strain: lineage4.1.2;lineage4.6.2
Drug-resistance: Sensitive

Drug1ResistanceSupporting Mutations (frequency)
Isoniazid
Rifampicin
Ethambutol
Pyrazinamide
Streptomycin
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.6.2Euro-AmericanT;LAMRD726

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5386c.147G>C1.000
gyrB5401c.162C>A1.000
gyrB5803c.564A>G1.000
gyrB5807p.Val190Ile1.000
gyrB5821c.582G>T1.000
gyrB5824c.585A>G1.000
gyrB5833c.594G>A1.000
gyrB5839c.600C>G1.000
gyrB5848c.609G>C1.000
gyrB5858p.Asn207Glu1.000
gyrB5863c.624G>C1.000
gyrB5869c.630C>T1.000
gyrB5873c.634A>C1.000
gyrB5884c.645A>G1.000
gyrB5893c.654C>G1.000
gyrB5896c.657C>G1.000
gyrB5902c.663A>G1.000
gyrB5992c.753T>C1.000
gyrB5998c.759T>C1.000
gyrB6013c.774G>C1.000
gyrB6022c.783G>C1.000
gyrB6025c.786A>G1.000
gyrB6045p.Asn269Thr1.000
gyrB6100c.861G>C1.000
gyrB6115c.876A>G1.000
gyrB6127c.888G>C1.000
gyrB6133c.894G>C1.000
gyrB6136c.897G>A1.000
gyrB6148c.909C>T0.988
gyrB6157c.918C>T0.988
gyrB6160c.921C>G0.989
gyrB6169c.930C>G0.990
gyrB6196c.957C>T1.000
gyrB6250c.1011A>C1.000
gyrB6253c.1014G>C0.923
gyrB6265c.1026C>T0.983
gyrB6268c.1029C>G1.000
gyrB6280c.1041T>C1.000
gyrB6286c.1047T>C1.000
gyrB6292c.1053G>T1.000
gyrB6295c.1056A>G1.000
gyrB6298c.1059C>T0.988
gyrB6307c.1068T>G1.000
gyrB6362c.1123T>C1.000
gyrB6367c.1128C>T1.000
gyrB6382c.1143A>G1.000
gyrB6388c.1149T>C1.000
gyrB6391c.1152G>T1.000
gyrB6398p.Val387Ile1.000
gyrB6403c.1164T>C1.000
gyrB6409c.1170A>G1.000
gyrB6415c.1176G>C1.000
gyrB6496c.1257G>C1.000
gyrB6508c.1269A>C1.000
gyrB6511c.1272A>T1.000
gyrB6515c.1276T>C1.000
gyrB6520c.1281G>C1.000
gyrB6535c.1296C>T1.000
gyrB6547c.1308T>C1.000
gyrB6550c.1311A>T1.000
gyrB6568c.1329C>G1.000
gyrB6577c.1338T>C1.000
gyrB6583c.1344G>C1.000
gyrB6590p.Arg451Thr0.987
gyrB6598c.1359C>G1.000
gyrB6610c.1371C>G1.000
gyrB6613c.1374A>G1.000
gyrB6616c.1377A>G1.000
gyrB6622c.1383C>T1.000
gyrB6634c.1395T>C1.000
gyrB6637c.1398T>G1.000
gyrB6640c.1401A>C1.000
gyrB6643c.1404A>G1.000
gyrB6646c.1407C>T1.000
gyrB6673c.1434A>C1.000
gyrB6674c.1435C>T0.951
gyrB6680c.1441C>T0.990
gyrB6688c.1449C>T0.991
gyrB6700c.1461T>C1.000
gyrB6703c.1464G>C1.000
gyrB6706c.1467G>A0.985
gyrB6709c.1470A>G1.000
gyrB6712c.1473G>C1.000
gyrB6715c.1476C>T0.985
gyrB6727c.1488G>T0.986
gyrB6728c.1489C>T1.000
gyrB6751c.1512G>C1.000
gyrB6760c.1521G>C1.000
gyrB6775c.1536G>T1.000
gyrB6793c.1554T>C1.000
gyrB6797p.Gly520Ser1.000
gyrB6808c.1569C>G1.000
gyrB6811c.1572C>T1.000
gyrB6824c.1585C>T1.000
gyrB6844c.1605T>C1.000
gyrB6850c.1611C>T1.000
gyrB6853c.1614A>G1.000
gyrB6856c.1617T>C1.000
gyrB6859c.1620T>C1.000
gyrB6869c.1630T>C1.000
gyrB6872c.1633T>C1.000
gyrB6877c.1638G>C1.000
gyrB6878c.1639T>C1.000
gyrB6949c.1710A>G1.000
gyrB6966c.1728 1728del0.991
gyrA7343c.42G>C1.000
gyrA7349c.48A>G1.000
gyrA7355c.54T>C1.000
gyrA7362p.Glu21Gln1.000
gyrA7367p.Gln22His1.000
gyrA7370c.69G>A1.000
gyrA7382c.81C>T1.000
gyrA7391c.90C>T1.000
gyrA7394c.93T>C1.000
gyrA7412c.111C>G1.000
gyrA7418c.117C>G1.000
gyrA7433c.132G>A1.000
gyrA7442c.141G>C1.000
gyrA7460c.159C>A1.000
gyrA7463c.162G>C1.000
gyrA7469c.168C>G1.000
gyrA7472c.171T>C1.000
gyrA7475c.174A>G1.000
gyrA7480p.Phe60Tyr1.000
gyrA7484c.183T>C1.000
gyrA7487c.186C>G1.000
gyrA7496c.195C>T1.000
gyrA7523c.222C>G1.000
gyrA7526c.225G>C1.000
gyrA7532c.231T>G1.000
gyrA7541c.240C>G1.000
gyrA7547c.246C>T0.994
gyrA7565c.264C>T1.000
gyrA7585p.Ser95Thr1.000
gyrA7592c.291G>C1.000
gyrA7607c.306C>G1.000
gyrA7619c.318C>T1.000
gyrA7631c.330G>C1.000
gyrA7637c.336C>T1.000
gyrA7652c.351C>T0.994
gyrA7658c.357A>G1.000
gyrA7664c.363T>C1.000
gyrA7670c.369A>C1.000
gyrA7671p.Pro124Ala1.000
gyrA7676c.375G>C1.000
gyrA7683c.382A>C1.000
gyrA7694c.393A>G1.000
gyrA7710c.409T>C1.000
gyrA7715c.414G>C1.000
gyrA7728c.427A>C0.994
gyrA7760c.459C>A1.000
gyrA7763c.462T>G1.000
gyrA7793c.492G>C1.000
gyrA7799c.498A>G1.000
gyrA7802c.501C>G1.000
gyrA7832c.531G>C1.000
gyrA7835c.534A>G0.994
gyrA7841c.540C>T1.000
gyrA7847c.546G>T1.000
gyrA7859c.558A>C1.000
gyrA7865c.564T>C1.000
gyrA7886c.585T>G1.000
gyrA7890c.589C>T1.000
gyrA7898p.Asp199Glu1.000
gyrA7906p.Phe202Tyr1.000
gyrA7911p.Ala204Cys1.000
gyrA7916c.615G>C1.000
gyrA7922c.621T>C1.000
gyrA7928p.Asp209Glu1.000
gyrA7934c.633C>T1.000
gyrA7942p.Glu214Ala1.000
gyrA8120c.819G>A1.000
gyrA8121c.820T>C1.000
gyrA8129c.828T>C1.000
gyrA8156c.855T>C1.000
gyrA8174c.873C>G1.000
gyrA8177c.876A>T1.000
gyrA8198c.897T>C1.000
gyrA8207c.906T>C1.000
gyrA8219c.918T>C1.000
gyrA8225c.924T>C1.000
gyrA8228c.927G>C1.000
gyrA8231c.930C>G1.000
gyrA8235c.934T>C1.000
gyrA8240c.939C>A1.000
gyrA8246c.945C>G1.000
gyrA8247p.Ile316Val1.000
gyrA8253p.Ile318Leu1.000
gyrA8267c.966G>C1.000
gyrA8270c.969G>C1.000
gyrA8273c.972C>G1.000
gyrA8279c.978G>C1.000
gyrA8283p.Ile328Leu1.000
gyrA8288c.987T>C1.000
gyrA8294c.993T>C1.000
gyrA8318c.1017C>G1.000
gyrA8319c.1018A>T1.000
gyrA8324c.1023T>C1.000
gyrA8330c.1029C>G1.000
gyrA8339c.1038A>G1.000
gyrA8340p.Ala347Ser1.000
gyrA8360c.1059G>C1.000
gyrA8372c.1071G>C1.000
gyrA8382p.Leu361Met1.000
gyrA8390c.1089C>G1.000
gyrA8393c.1092T>C1.000
gyrA8399c.1098T>C1.000
gyrA8401p.Asp367Ala1.000
gyrA8408c.1107A>G1.000
gyrA8420c.1119T>C1.000
gyrA8421p.Val374Ile1.000
gyrA8433p.Thr378Arg1.000
gyrA8453c.1152A>C1.000
gyrA8462c.1161A>G1.000
gyrA8465c.1164C>T1.000
gyrA8471c.1170T>C1.000
gyrA8480c.1179C>G1.000
gyrA8481c.1180C>T1.000
gyrA8486c.1185T>C1.000
gyrA8504c.1203G>C1.000
gyrA8507c.1206C>T1.000
gyrA8510c.1209G>A1.000
gyrA8513c.1212C>G1.000
gyrA8516c.1215T>C1.000
gyrA8519c.1218A>G1.000
gyrA8520c.1219C>T1.000
gyrA8528c.1227G>C1.000
gyrA8531c.1230G>C1.000
gyrA8534c.1233G>C1.000
gyrA8537c.1236G>A1.000
gyrA8546p.Asp415Glu1.000
gyrA8555c.1254G>C1.000
gyrA8561c.1260A>C1.000
gyrA8597c.1296C>T1.000
gyrA8603c.1302A>C1.000
gyrA8609c.1308G>C1.000
gyrA8619c.1318T>C1.000
gyrA8624c.1323G>T1.000
gyrA8627c.1326C>G1.000
gyrA8628c.1327C>T1.000
gyrA8633c.1332C>T1.000
gyrA8636c.1335A>C1.000
gyrA8645c.1344C>T1.000
gyrA8649p.Arg450Lys1.000
gyrA8663c.1362C>T1.000
gyrA8672c.1371A>G1.000
gyrA8693c.1392T>C1.000
gyrA8696c.1395G>C1.000
gyrA8699c.1398A>G1.000
gyrA8711c.1410A>C1.000
gyrA8717c.1416C>G1.000
gyrA8729c.1428T>C1.000
gyrA8731p.Gly477Ala1.000
gyrA8747c.1446A>G1.000
gyrA8750c.1449C>G1.000
gyrA8756c.1455A>G1.000
gyrA8762c.1461G>C1.000
gyrA8765p.Asp488Glu1.000
gyrA8767p.Arg489Lys1.000
gyrA8774c.1473C>T1.000
gyrA8786c.1485T>C1.000
gyrA8796p.Ile499Val1.000
gyrA8799p.Ala500Pro1.000
gyrA8810c.1509A>C1.000
gyrA8828c.1527T>C1.000
gyrA8829c.1528T>C1.000
gyrA8840c.1539C>G1.000
gyrA8843c.1542G>A1.000
gyrA8852c.1551T>G1.000
gyrA8858c.1557T>G1.000
gyrA8867c.1566A>G1.000
gyrA8897c.1596T>C1.000
gyrA8903c.1602T>C1.000
gyrA8909c.1608C>T1.000
gyrA8915c.1614A>G0.993
gyrA8939c.1638T>C1.000
gyrA8946c.1645T>C1.000
gyrA8952p.Gln551Ala0.989
gyrA8967p.Ala556Asn1.000
gyrA8987c.1686C>G1.000
gyrA8990c.1689C>G1.000
gyrA8996c.1695T>C1.000
gyrA8998p.Leu566Trp1.000
gyrA9017c.1716C>A1.000
gyrA9023c.1722A>T1.000
gyrA9026c.1725G>C0.990
gyrA9029c.1728T>G1.000
gyrA9032c.1731T>C1.000
gyrA9051c.1750T>C1.000
gyrA9056c.1755C>G1.000
gyrA9059c.1758G>A0.984
gyrA9065c.1764C>G1.000
gyrA9068c.1767G>T1.000
gyrA9071c.1770G>C1.000
gyrA9080c.1779G>A1.000
gyrA9086c.1785C>T1.000
gyrA9092c.1791C>G1.000
gyrA9096c.1795C>T1.000
gyrA9099c.1798T>C1.000
gyrA9113c.1812C>G1.000
gyrA9119c.1818A>G1.000
gyrA9134c.1833C>G0.963
gyrA9161c.1860C>G0.971
gyrA9182c.1881T>C1.000
gyrA9191c.1890G>C1.000
gyrA9200c.1899A>G1.000
gyrA9213p.Thr638Val1.000
gyrA9224c.1923C>T1.000
gyrA9227c.1926C>G1.000
gyrA9230c.1929T>C1.000
gyrA9233c.1932C>T1.000
gyrA9236c.1935G>C1.000
gyrA9242c.1941A>C1.000
gyrA9252p.Val651Ile1.000
gyrA9266c.1965C>T0.979
gyrA9267p.Asn656Gly0.978
gyrA9272c.1971C>T0.978
gyrA9275c.1974G>A0.979
gyrA9296c.1995T>C1.000
gyrA9304p.Gly668Glu1.000
gyrA9324c.2023T>A0.992
gyrA9335c.2034G>T1.000
gyrA9345c.2044A>C0.993
gyrA9353c.2052G>C0.994
gyrA9356c.2055G>A0.994
gyrA9362c.2061C>T0.982
gyrA9377c.2076A>G0.988
gyrA9383c.2082T>C1.000
gyrA9386c.2085T>G1.000
gyrA9419c.2118T>C1.000
gyrA9420p.Ile707Glu1.000
gyrA9432c.2131C>T1.000
gyrA9503c.2202T>A1.000
gyrA9518c.2217A>G1.000
gyrA9522p.Pro741Thr1.000
gyrA9527c.2226A>C1.000
gyrA9536c.2235C>T1.000
gyrA9626c.2325T>C1.000
gyrA9630p.Val777Ile1.000
gyrA9635c.2334T>C0.978
gyrA9641c.2340C>T1.000
gyrA9644c.2343T>C1.000
gyrA9656c.2355C>G1.000
gyrA9662c.2361G>C1.000
gyrA9668c.2367C>T1.000
gyrA9683c.2382G>T1.000
gyrA9689c.2388G>T1.000
gyrA9704c.2403T>C1.000
gyrA9707c.2406G>C1.000
gyrA9716c.2415T>C1.000
gyrA9725p.Glu808Asp1.000
gyrA9738p.Leu813Ile1.000
gyrA9743c.2442C>G1.000
gyrA9746c.2445C>T1.000
rpoB759575c.-232C>T1.000
rpoB759604c.-203A>G1.000
rpoB759606c.-201T>A1.000
rpoB759788c.-19A>G1.000
rpoB759884c.78A>C1.000
rpoB759887c.81C>A1.000
rpoB759893c.87G>A1.000
rpoB759896c.90A>G1.000
rpoB759902c.96G>A1.000
rpoB759905c.99C>T1.000
rpoB759911c.105C>T1.000
rpoB759914c.108T>C1.000
rpoB759920c.114G>C1.000
rpoB759929c.123A>G1.000
rpoB759944c.138A>G1.000
rpoB759947c.141C>G1.000
rpoB759950c.144T>C1.000
rpoB759956c.150C>T1.000
rpoB759962c.156C>G1.000
rpoB759968c.162G>C1.000
rpoB759974p.Glu56Asp1.000
rpoB760046c.240G>C1.000
rpoB760059p.Tyr85Glu1.000
rpoB760067c.261G>C1.000
rpoB760070c.264T>C1.000
rpoB760082c.276C>T1.000
rpoB760088c.282C>G1.000
rpoB760091c.285G>C1.000
rpoB760101c.295T>C1.000
rpoB760104c.298T>A1.000
rpoB760112c.306T>C1.000
rpoB760118c.312T>G1.000
rpoB760121c.315T>C1.000
rpoB760130p.Asp108Glu1.000
rpoB760139c.333A>G1.000
rpoB760142c.336C>G0.992
rpoB760181c.375T>C1.000
rpoB760184c.378A>G1.000
rpoB760196c.390C>G1.000
rpoB760235c.429T>C1.000
rpoB760244c.438G>C1.000
rpoB760283c.477G>C1.000
rpoB760298c.492G>C1.000
rpoB760310c.504G>C1.000
rpoB760316c.510C>G1.000
rpoB760325c.519G>C1.000
rpoB760331c.525G>C1.000
rpoB760334c.528G>T0.987
rpoB760340c.534G>T0.987
rpoB760357p.Thr184Ser1.000
rpoB760361c.555T>C1.000
rpoB760376p.Asp190Glu1.000
rpoB760406c.600G>C0.978
rpoB760407p.Ser201Gly1.000
rpoB760415c.609C>T1.000
rpoB760424c.618C>G1.000
rpoB760430c.624T>C1.000
rpoB760460c.654G>C1.000
rpoB760475c.669A>G1.000
rpoB760478c.672C>T1.000
rpoB760481c.675G>T1.000
rpoB760484c.678A>G1.000
rpoB760511c.705G>C1.000
rpoB760514c.708C>T0.993
rpoB760522p.Ser239Asn0.993
rpoB760532c.726T>C1.000
rpoB760533p.Val243Thr1.000
rpoB760541c.735G>C1.000
rpoB760567p.Ser254Trp1.000
rpoB760571c.765G>C1.000
rpoB760585p.Asn260Ser1.000
rpoB760591p.Val262Ala1.000
rpoB760595c.789C>T1.000
rpoB760596p.Thr264Pro1.000
rpoB760611c.805T>C1.000
rpoB760634c.828T>C1.000
rpoB760646c.840C>G1.000
rpoB760655c.849A>G1.000
rpoB760658c.852G>A1.000
rpoB760661c.855A>C1.000
rpoB760670c.864G>C1.000
rpoB760674c.868T>C1.000
rpoB760679c.873A>G1.000
rpoB760683c.877T>C1.000
rpoB760721c.915C>G1.000
rpoB760730c.924T>C1.000
rpoB760748c.942C>A1.000
rpoB760751c.945G>C1.000
rpoB760754c.948G>C1.000
rpoB760755p.His317Asn1.000
rpoB760759p.Val318Ala1.000
rpoB760764p.Glu320Gln0.991
rpoB760769c.963C>G1.000
rpoB760793c.987A>G1.000
rpoB760805c.999G>C1.000
rpoB760817c.1011A>G1.000
rpoB760820c.1014T>C1.000
rpoB760826c.1020C>G1.000
rpoB760830c.1024T>C1.000
rpoB760841c.1035T>C1.000
rpoB760859c.1053T>C1.000
rpoB760862c.1056G>C1.000
rpoB760877c.1071G>C1.000
rpoB760883c.1077G>C1.000
rpoB760886c.1080A>G1.000
rpoB760887p.Thr361Val1.000
rpoB760910c.1104C>T1.000
rpoB760916c.1110C>T1.000
rpoB760919c.1113C>T1.000
rpoB760925c.1119T>C1.000
rpoB760928c.1122G>C1.000
rpoB760931c.1125C>G1.000
rpoB760934c.1128C>T1.000
rpoB760946c.1140A>G1.000
rpoB760949c.1143C>T0.992
rpoB760965p.Met387Leu1.000
rpoB760970c.1164G>C0.992
rpoB760973c.1167G>C1.000
rpoB760982c.1176G>C1.000
rpoB760985c.1179G>C1.000
rpoB760988c.1182C>G1.000
rpoB760991c.1185G>T1.000
rpoB760997c.1191G>C1.000
rpoB761015c.1209G>C1.000
rpoB761027c.1221A>G1.000
rpoB761036c.1230G>C1.000
rpoB761037c.1231T>C1.000
rpoB761051c.1245G>T1.000
rpoB761054c.1248G>C1.000
rpoB761057c.1251G>C1.000
rpoB761060c.1254C>G1.000
rpoB761063c.1257C>G1.000
rpoB761084c.1278C>T1.000
rpoB761097c.1291A>T1.000
rpoB761102c.1296A>G1.000
rpoB761126c.1320G>T1.000
rpoB761132c.1326G>T0.984
rpoB761133c.1327T>C1.000
rpoB761147c.1341C>T1.000
rpoB761150c.1344A>C1.000
rpoB761165c.1359G>C1.000
rpoB761180c.1374A>C0.993
rpoB761195c.1389G>C1.000
rpoB761198c.1392G>T1.000
rpoB761217p.Pro471Ala1.000
rpoB761220c.1414T>A1.000
rpoB761234c.1428G>C1.000
rpoB761249c.1443A>G1.000
rpoB761261c.1455G>T1.000
rpoB761264c.1458C>G1.000
rpoB761300c.1494G>C1.000
rpoB761318c.1512G>C1.000
rpoB761327c.1521A>G1.000
rpoB761345c.1539G>C1.000
rpoB761354c.1548C>T1.000
rpoB761360c.1554T>C1.000
rpoB761362p.Ser519Thr1.000
rpoB761367p.Glu521Gln1.000
rpoB761374p.Val523Asp1.000
rpoB761408c.1602G>C1.000
rpoB761414c.1608A>G1.000
rpoB761423c.1617T>C1.000
rpoB761435c.1629T>C1.000
rpoB761438c.1632G>C1.000
rpoB761444c.1638T>C1.000
rpoB761537c.1731C>G1.000
rpoB761552c.1746G>T1.000
rpoB761555c.1749G>C0.993
rpoB761558c.1752C>G1.000
rpoB761570c.1764T>C1.000
rpoB761573c.1767C>G1.000
rpoB761579c.1773G>C1.000
rpoB761600c.1794T>C1.000
rpoB761606c.1800C>G1.000
rpoB761612c.1806G>T1.000
rpoB761615c.1809A>C1.000
rpoB761636c.1830G>T1.000
rpoB761645c.1839C>G1.000
rpoB761648c.1842T>C1.000
rpoB761666c.1860G>C1.000
rpoB761669c.1863C>T1.000
rpoB761675c.1869G>C1.000
rpoB761687c.1881C>T1.000
rpoB761690c.1884G>C0.992
rpoB761693c.1887G>C1.000
rpoB761708c.1902C>T1.000
rpoB761718p.Ala638Ser1.000
rpoB761721c.1916 1916del1.000
rpoB761729r.1923c>cg0.991
rpoC763375c.6C>A1.000
rpoC763408c.39T>C1.000
rpoC763411c.42T>G1.000
rpoC763414c.45T>C1.000
rpoC763417c.48C>T1.000
rpoC763423p.Glu18Asp1.000
rpoC763430c.61A>C1.000
rpoC763433p.Gln22Asn0.983
rpoC763443p.Tyr25Phe1.000
rpoC763456c.87A>G1.000
rpoC763468c.99G>C1.000
rpoC763486c.117T>C1.000
rpoC763492c.123G>C1.000
rpoC763528c.159G>A1.000
rpoC763546c.177A>G1.000
rpoC763558c.189C>T1.000
rpoC763570c.201G>C1.000
rpoC763573c.204G>C0.991
rpoC763594c.225C>T1.000
rpoC763615c.246G>C1.000
rpoC763618c.249C>T1.000
rpoC763633c.264T>C1.000
rpoC763657c.288G>A1.000
rpoC763660c.291T>G1.000
rpoC763666c.297G>A1.000
rpoC763675c.306C>G1.000
rpoC763699c.330G>T0.991
rpoC763702c.333C>G1.000
rpoC763709c.340C>T0.990
rpoC763714c.345G>C1.000
rpoC763717c.348T>C1.000
rpoC763723c.354G>C1.000
rpoC763741c.372C>T1.000
rpoC763747c.378G>A1.000
rpoC763765c.396T>G1.000
rpoC763783c.414G>C1.000
rpoC763792p.Glu141Asp1.000
rpoC763807c.438T>C1.000
rpoC763813c.444C>G1.000
rpoC763831c.462A>G1.000
rpoC763837c.468G>C1.000
rpoC763840c.471G>C1.000
rpoC763858c.489A>G1.000
rpoC763861c.492C>T1.000
rpoC763871p.Gly168Ser1.000
rpoC763876p.Glu169Asp1.000
rpoC763879c.510A>G1.000
rpoC763891c.522G>A0.992
rpoC763894c.525A>G1.000
rpoC763900c.531G>C1.000
rpoC763921c.552G>C1.000
rpoC763924c.555G>A1.000
rpoC763933c.564C>T1.000
rpoC763940p.Ala191Ser1.000
rpoC763945c.576T>C1.000
rpoC763947p.Ala193Val1.000
rpoC763951c.582G>C1.000
rpoC763960c.591T>G1.000
rpoC763978c.609C>T1.000
rpoC763987c.618C>T1.000
rpoC763991p.Ile208Leu1.000
rpoC763996c.627T>C1.000
rpoC764002c.633C>G1.000
rpoC764005c.636G>C1.000
rpoC764024c.655T>C1.000
rpoC764029p.Glu220Asp1.000
rpoC764032p.Asp221Glu1.000
rpoC764040p.Ser224Thr0.991
rpoC764044c.675T>C1.000
rpoC764059c.690G>T1.000
rpoC764071c.702G>C1.000
rpoC764077c.708C>G1.000
rpoC764083c.714A>G1.000
rpoC764084p.Asn239Val0.983
rpoC764098c.729A>G0.935
rpoC764101c.732C>G0.935
rpoC764102p.Val245Gln0.934
rpoC764131c.762T>C1.000
rpoC764153p.Gln262Lys0.993
rpoC764161c.792G>C0.993
rpoC764182p.Asp271Glu0.993
rpoC764188c.819A>G1.000
rpoC764195c.826T>A1.000
rpoC764203c.834G>T1.000
rpoC764206p.Asp279Glu1.000
rpoC764207p.Val280Thr0.988
rpoC764215c.846A>C1.000
rpoC764217p.Asn283Ser0.989
rpoC764239c.870T>G1.000
rpoC764254c.885G>C1.000
rpoC764263c.894G>C1.000
rpoC764266c.897T>C1.000
rpoC764272c.903G>C0.994
rpoC764278c.909A>G1.000
rpoC764293c.924G>C1.000
rpoC764297p.Met310Leu1.000
rpoC764344c.975C>T0.994
rpoC764353c.984G>T0.994
rpoC764365c.996C>T0.994
rpoC764371c.1002G>C0.994
rpoC764380c.1011G>C0.994
rpoC764387c.1018T>C1.000
rpoC764405c.1036A>C1.000
rpoC764431c.1062G>C1.000
rpoC764434c.1065A>G1.000
rpoC764435c.1066A>C0.991
rpoC764446c.1077T>C1.000
rpoC764449c.1080G>C1.000
rpoC764452c.1083T>C1.000
rpoC764458c.1089G>C1.000
rpoC764461c.1092A>G1.000
rpoC764485c.1116G>C0.994
rpoC764491c.1122G>T0.989
rpoC764497c.1128A>G1.000
rpoC764500c.1131C>G0.988
rpoC764521c.1152T>C1.000
rpoC764527c.1158C>T1.000
rpoC764536c.1167G>T1.000
rpoC764539c.1170C>G1.000
rpoC764548c.1179G>T1.000
rpoC764575c.1206T>G1.000
rpoC764605c.1236G>C0.993
rpoC764611c.1242G>T1.000
rpoC764623c.1254C>G0.985
rpoC764626c.1257C>T0.985
rpoC764632c.1263T>C0.992
rpoC764650c.1281G>T1.000
rpoC764701c.1332C>G1.000
rpoC764707c.1338G>C0.993
rpoC764713c.1344G>T0.979
rpoC764716c.1347G>C1.000
rpoC764746c.1377G>T0.988
rpoC764752c.1383G>C1.000
rpoC764758c.1389C>G0.994
rpoC764764c.1395T>C1.000
rpoC764803c.1434C>T0.994
rpoC764809c.1440C>T1.000
rpoC764815c.1446A>G1.000
rpoC764827c.1458G>C1.000
rpoC764858c.1489T>C1.000
rpoC764869c.1500C>T0.993
rpoC764875c.1506C>T0.993
rpoC764878c.1509C>G0.993
rpoC764887c.1518G>C0.993
rpoC764888c.1519T>C1.000
rpoC764911c.1542A>G1.000
rpoC764912p.Met515Gln1.000
rpoC764935c.1566T>C1.000
rpoC764948c.1579T>C1.000
rpoC764968c.1599T>C1.000
rpoC765007c.1638T>C1.000
rpoC765008c.1639T>C1.000
rpoC765011c.1642A>T1.000
rpoC765016c.1647C>A1.000
rpoC765019c.1650A>G1.000
rpoC765034c.1665T>C1.000
rpoC765040c.1671T>C1.000
rpoC765041c.1672T>C1.000
rpoC765047c.1678T>C1.000
rpoC765052c.1683C>G1.000
rpoC765055c.1686C>G1.000
rpoC765073c.1704G>C1.000
rpoC765076c.1707A>G1.000
rpoC765079c.1710T>G1.000
rpoC765082c.1713G>T1.000
rpoC765083p.Arg572Lys1.000
rpoC765089c.1720T>C1.000
rpoC765103c.1734G>T1.000
rpoC765121c.1752G>C1.000
rpoC765259c.1890G>C1.000
rpoC765383p.Met672Leu1.000
rpoC765403c.2034G>C0.992
rpoC765404p.Leu679Lys1.000
rpoC765409c.2040T>C1.000
rpoC765412c.2043T>C0.993
rpoC765425p.Lys686Glu0.994
rpoC765445c.2076G>C0.994
rpoC765452p.Ala695Arg0.993
rpoC765478c.2109T>C1.000
rpoC765480p.Tyr704Phe0.994
rpoC765496c.2127C>G0.994
rpoC765499c.2130C>G1.000
rpoC765529c.2160C>T0.964
rpoC765533p.Tyr722His1.000
rpoC765547c.2178C>T0.973
rpoC765548c.2179A>T0.972
rpoC765553c.2184C>T0.972
rpoC765556c.2187G>C0.972
rpoC765562c.2193G>C1.000
rpoC765577c.2208G>T1.000
rpoC765591p.Arg741Gln1.000
rpoC765596p.Lys743Gln0.960
rpoC765671p.Asp768Asn1.000
rpoC765686p.Ala773Ser1.000
rpoC765694c.2325G>C1.000
rpoC765695p.Glu776Lys1.000
rpoC765700c.2331T>C1.000
rpoC765704p.Lys779Gln1.000
rpoC765709p.Glu780Asp1.000
rpoC765718p.Asp783Glu0.982
rpoC765724c.2355C>G1.000
rpoC765728p.Gln787Lys1.000
rpoC765734c.2365T>C1.000
rpoC765737p.Arg790Glu1.000
rpoC765743p.His792Tyr1.000
rpoC765751c.2382C>G1.000
rpoC765753p.Asp795Ala1.000
rpoC765772c.2403C>G1.000
rpoC765777c.2409 2409del0.967
rpoC765778r.2409c>g1.000
rpsL781559c.-1G>C1.000
rpsL781572p.Gln5Asn1.000
rpsL781595c.36T>C1.000
rpsL781598c.39G>C1.000
rpsL781605p.Ile16Val1.000
rpsL781608p.Ser17Ala1.000
rpsL781628c.69T>C1.000
rpsL781631c.72G>C1.000
rpsL781649c.90T>C1.000
rpsL781655c.96T>C1.000
rpsL781658c.99A>G1.000
rpsL781682c.123T>C1.000
rpsL781709c.150G>C1.000
rpsL781715c.156T>C1.000
rpsL781718c.159C>T1.000
rpsL781728c.169T>C1.000
rpsL781742c.183C>T1.000
rpsL781751c.192G>C1.000
rpsL781754c.195G>T1.000
rpsL781760c.201T>C1.000
rpsL781766c.207C>T0.991
rpsL781772c.213C>T1.000
rpsL781808c.249C>T0.992
rpsL781811c.252C>T1.000
rpsL781814c.255C>T1.000
rpsL781817c.258G>T0.992
rpsL781829c.270G>C0.992
rpsL781832c.273T>C1.000
rpsL781838c.279G>C1.000
rpsL781841c.282C>T1.000
rpsL781859c.300T>G1.000
rpsL781868c.309T>C1.000
rpsL781871c.312G>C1.000
rpsL781892c.333A>G1.000
rpsL781898c.339A>C1.000
rpsL781901c.342C>T1.000
rpsL781916c.357T>C1.000
rpsL781929p.Gly124Ser1.000
rplC800844c.36T>C1.000
rplC800856c.48A>G1.000
rplC800862c.54C>T1.000
rplC800865c.57A>G1.000
rplC800867p.Ser20Asn1.000
rplC800873p.Arg22Lys1.000
rplC800877c.69A>C1.000
rplC800880c.72A>C1.000
rplC800889c.81C>G1.000
rplC800892c.84G>C1.000
rplC800895c.87C>G1.000
rplC800904c.96G>C1.000
rplC800916c.108A>G1.000
rplC800921p.Arg38Leu1.000
rplC800928c.120C>T1.000
rplC800931c.123G>C1.000
rplC800937c.129A>G1.000
rplC800946c.138T>C1.000
rplC800949c.141T>C1.000
rplC800964c.156G>C1.000
rplC800985c.177A>G1.000
rplC801003c.195G>C1.000
rplC801004p.Leu66Val1.000
rplC801009c.201A>C1.000
rplC801019p.Thr71Ala1.000
rplC801027c.219C>G1.000
rplC801030c.222C>T1.000
rplC801039c.231A>G1.000
rplC801045c.237A>C1.000
rplC801046p.Tyr80His1.000
rplC801174c.366T>C1.000
rplC801195c.387G>T1.000
rplC801205p.Arg133Ala1.000
rplC801220p.Ser138Ala0.994
rplC801246c.438C>T0.994
rplC801252c.444G>C1.000
rplC801264c.456C>T1.000
rplC801267c.459A>C1.000
rplC801270c.462T>C1.000
rplC801276c.468G>C1.000
rplC801281p.Ala158Gly1.000
rplC801285c.477G>C1.000
rplC801307p.Ala167Ser1.000
rplC801312c.504G>C1.000
rplC801315c.507G>T1.000
rplC801324c.516T>C1.000
rplC801385c.577C>T1.000
rrs1471922r.77gt>g1.000
rrs1471925r.80t>c1.000
rrs1471931r.86ga>g1.000
rrs1471934r.89a>g1.000
rrs1471986r.141c>t1.000
rrs1472031r.186g>c1.000
rrs1472033r.188a>c1.000
rrs1472035r.190g>t1.000
rrs1472040r.195t>g1.000
rrs1472041r.196c>t1.000
rrs1472042r.197t>g1.000
rrs1472053r.208agc>a1.000
rrs1472061r.216a>t1.000
rrs1472075r.230a>g1.000
rrs1472106r.261g>a0.994
rrs1472108r.263c>t1.000
rrs1472150r.305t>a0.995
rrs1472251r.406g>a1.000
rrs1472286r.441c>a0.955
rrs1472287r.442c>t1.000
rrs1472289r.444t>g1.000
rrs1472290r.445c>g1.000
rrs1472297r.452ggtccgggttctct>g1.000
rrs1472312r.467g>gc1.000
rrs1472313r.468g>a1.000
rrs1472315r.470t>g1.000
rrs1472324r.479g>c1.000
rrs1472325r.480g>c1.000
rrs1472327r.482g>a1.000
rrs1472328r.483g>t1.000
rrs1472337r.492c>g1.000
rrs1472380r.535g>c0.994
rrs1472446r.601t>a0.994
rrs1472452r.607g>a0.994
rrs1472464r.619a>g0.994
rrs1472847r.1002g>c0.992
rrs1472848r.1003t>a1.000
rrs1472849r.1004c>g1.000
rrs1472858r.1013g>t0.992
rrs1472859r.1014g>t1.000
rrs1472860r.1015c>g1.000
rrs1472973r.1128a>t1.000
rrs1473104r.1259c>t1.000
rrs1473110r.1265t>g1.000
rrs1473111r.1266a>g1.000
rrs1473120r.1275c>ct0.911
rrs1473123r.1278a>c1.000
rrs1473276r.1431a>g1.000
rrs1473290r.1445c>t1.000
rrs1473291r.1446g>gt1.000
rrs1473301r.1456t>c1.000
rrl1473543c.-115C>T1.000
rrl1473568c.-90G>T1.000
rrl1473569c.-89A>T1.000
rrl1473570c.-88A>T1.000
rrl1473571c.-87C>G1.000
rrl1473668r.11c>t1.000
rrl1473696r.39t>c1.000
rrl1473697r.40c>t1.000
rrl1473699r.42a>g1.000
rrl1473717r.60g>t1.000
rrl1473746r.89t>c1.000
rrl1473758r.101g>t1.000
rrl1473770r.113t>g1.000
rrl1473788r.131a>g1.000
rrl1473806r.149c>t1.000
rrl1473807r.150t>c1.000
rrl1473811r.154c>ct0.984
rrl1473814r.157at>a1.000
rrl1473823r.166t>c1.000
rrl1473829r.172g>t1.000
rrl1473830r.173t>g1.000
rrl1473831r.174g>t1.000
rrl1473832r.175c>a1.000
rrl1473876r.219g>a1.000
rrl1473884r.227c>ca0.891
rrl1473886r.229a>ac0.891
rrl1473887r.230t>a1.000
rrl1473898r.241c>t1.000
rrl1473899r.242a>g1.000
rrl1473916r.259c>a1.000
rrl1473922r.265a>g1.000
rrl1473923r.266c>g1.000
rrl1473935r.278c>t1.000
rrl1473937r.280c>t1.000
rrl1473943r.286g>t1.000
rrl1473945r.288t>a1.000
rrl1473946r.289a>t1.000
rrl1474022r.365g>a1.000
rrl1474026r.369c>t1.000
rrl1474044r.387c>t1.000
rrl1474045r.388c>t1.000
rrl1474053r.396g>a1.000
rrl1474054r.397t>c1.000
rrl1474083r.426c>t0.989
rrl1474091r.434c>t1.000
rrl1474093r.436g>a1.000
rrl1474096r.439c>t1.000
rrl1474099r.442g>a1.000
rrl1474108r.451c>t1.000
rrl1474110r.453a>g0.172
rrl1474110r.453a>atggtg1.000
rrl1474135r.478g>a1.000
rrl1474140r.483c>t1.000
rrl1474151r.494c>t1.000
rrl1474174r.517a>g1.000
rrl1474181r.524c>t1.000
rrl1474183r.526t>c1.000
rrl1474185r.528g>a1.000
rrl1474186r.529a>g1.000
rrl1474249r.592g>t1.000
rrl1474266r.609t>c1.000
rrl1474269r.612c>t1.000
rrl1474301r.644g>c1.000
rrl1474303r.646a>t1.000
rrl1474306r.649a>t1.000
rrl1474362r.705a>g1.000
rrl1474374r.717t>g1.000
rrl1474414r.757c>t1.000
rrl1474420r.763cgcgcat>c1.000
rrl1474428r.771c>g1.000
rrl1474429r.772g>t0.429
rrl1474430r.773c>a1.000
rrl1474432r.775c>t1.000
rrl1474436r.779t>tg1.000
rrl1474438r.781a>t1.000
rrl1474439r.782a>g1.000
rrl1474446r.789c>t1.000
rrl1474626r.969t>c0.976
rrl1474627r.970g>a0.988
rrl1474629r.972g>a1.000
rrl1474632r.975g>t0.988
rrl1474636r.979a>t1.000
rrl1474637r.980c>t1.000
rrl1474638r.981c>g1.000
rrl1474639r.982g>t1.000
rrl1474640r.983c>t1.000
rrl1474673r.1016t>c1.000
rrl1474676r.1019t>a1.000
rrl1474677r.1020a>g1.000
rrl1474710r.1053t>a1.000
rrl1474711r.1054g>c1.000
rrl1474712r.1055g>a1.000
rrl1474713r.1056t>a1.000
rrl1474717r.1060a>g1.000
rrl1474720r.1063c>t0.991
rrl1474753r.1096a>g1.000
rrl1474760r.1103a>g1.000
rrl1474794r.1137c>t1.000
rrl1474812r.1155g>a0.994
rrl1474830r.1173a>g1.000
rrl1475031r.1374g>t1.000
rrl1475061r.1404c>a1.000
rrl1475062r.1405a>t1.000
rrl1475120r.1463g>t1.000
rrl1475315r.1658a>t1.000
rrl1475353r.1696a>t1.000
rrl1475354r.1697a>g1.000
rrl1475355r.1698c>t1.000
rrl1475363r.1706c>t1.000
rrl1475374r.1717ggaga>g0.942
rrl1475382r.1725a>aaacg1.000
rrl1475395r.1738t>c1.000
rrl1475396r.1739c>g1.000
rrl1475397r.1740g>t1.000
rrl1475398r.1741c>t1.000
rrl1475402r.1745c>t1.000
rrl1475403r.1746t>a1.000
rrl1475404r.1747a>c1.000
rrl1475406r.1749t>g1.000
rrl1475419r.1762c>t1.000
rrl1475429r.1772g>t1.000
rrl1475452r.1795c>a1.000
rrl1475479r.1822c>g1.000
rrl1475483r.1826c>t0.995
rrl1475505r.1848g>a1.000
rrl1475526r.1869c>a1.000
rrl1475531r.1874c>t1.000
rrl1475544r.1887a>t0.995
rrl1475545r.1888t>g1.000
rrl1475602r.1945g>c1.000
rrl1475603r.1946g>c1.000
rrl1475604r.1947a>c1.000
rrl1475612r.1955g>c1.000
rrl1475615r.1958c>g1.000
rrl1475616r.1959a>g1.000
rrl1475618r.1961c>t1.000
rrl1475626r.1969t>c1.000
rrl1475629r.1972g>c1.000
rrl1475637r.1980t>g1.000
rrl1475638r.1981c>g1.000
rrl1475639r.1982c>g1.000
rrl1475643r.1986c>g1.000
rrl1475647r.1990g>c1.000
rrl1475659r.2002g>a1.000
rrl1475753r.2096c>t1.000
rrl1475762r.2105g>t1.000
rrl1475763r.2106c>t1.000
rrl1475764r.2107a>c1.000
rrl1475765r.2108a>g1.000
rrl1475775r.2118g>a1.000
rrl1475988r.2331a>g1.000
rrl1475991r.2334t>c1.000
rrl1475995r.2338g>a1.000
rrl1476044r.2387t>g1.000
rrl1476045r.2388g>t1.000
rrl1476049r.2392c>t0.992
rrl1476088r.2431a>c1.000
rrl1476099r.2442a>g1.000
rrl1476103r.2446c>g1.000
rrl1476105r.2448g>a1.000
rrl1476106r.2449a>t1.000
rrl1476110r.2453g>c1.000
rrl1476115r.2458t>c1.000
rrl1476131r.2474c>t1.000
rrl1476160r.2503t>c1.000
rrl1476214r.2557g>t0.994
rrl1476215r.2558c>t1.000
rrl1476224r.2567a>g1.000
rrl1476251r.2594t>g1.000
rrl1476256r.2599a>t1.000
rrl1476260r.2603a>g1.000
rrl1476281r.2624t>c1.000
rrl1476297r.2640c>t1.000
rrl1476299r.2642c>t1.000
rrl1476529r.2872a>g1.000
rrl1476540r.2883c>t1.000
rrl1476583r.2926g>a1.000
rrl1476584r.2927c>t1.000
rrl1476594r.2937c>t0.995
rrl1476597r.2940g>a1.000
rrl1476603r.2946g>a1.000
rrl1476628r.2971t>a1.000
rrl1476664r.3007t>c1.000
rrl1476665r.3008t>c1.000
rrl1476674r.3017t>c1.000
rrl1476679r.3022t>c1.000
rrl1476689r.3032a>t0.992
rrl1476690r.3033c>t1.000
rrl1476693r.3036g>a1.000
rrl1476695r.3038t>a1.000
rrl1476716r.3059a>c1.000
rrl1476723r.3066t>a1.000
rrl1476725r.3068c>t1.000
rrl1476726r.3069a>g1.000
rrl1476731r.3074g>a1.000
rrl1476732r.3075t>c1.000
rrl1476746r.3089t>c0.467
rrl1476750r.3093t>c1.000
rrl1476759r.3102t>c1.000
rrl1476770r.3113t>c1.000
rrl1476771r.3114g>a1.000
fabG11673490c.51A>C1.000
fabG11673493c.54C>A1.000
fabG11673499c.60T>C1.000
fabG11673505c.66A>T1.000
fabG11673523c.84G>C1.000
fabG11673529c.90G>A1.000
fabG11673532c.93C>T1.000
fabG11673535c.96A>G1.000
fabG11673541c.102G>T0.982
fabG11673542c.103C>T1.000
fabG11673556c.117C>G1.000
fabG11673565c.126G>C1.000
fabG11673580c.141T>C1.000
fabG11673586c.147C>G1.000
fabG11673589c.150A>C1.000
fabG11673595c.156A>C1.000
fabG11673596p.Lys53Glu1.000
fabG11673607c.168T>C1.000
fabG11673664c.225A>C1.000
fabG11673679c.240T>C1.000
fabG11673709c.270C>G1.000
fabG11673710p.Leu91Ile1.000
fabG11673716p.Ala93Gln1.000
fabG11673724c.285A>G0.992
fabG11673730c.291C>G0.985
fabG11673748c.309A>G1.000
fabG11673749p.Lys104Arg1.000
fabG11673760p.Lys107Asn0.994
fabG11673784c.345G>A0.994
fabG11673799c.360T>G1.000
fabG11673802c.363A>G1.000
fabG11673808c.369A>G0.993
fabG11673811c.372G>A1.000
fabG11673817c.378C>T1.000
fabG11673829p.Asn130Lys1.000
fabG11673830p.Lys131Arg1.000
fabG11673838c.399T>G1.000
fabG11673844p.Met135Ile1.000
fabG11673847c.408A>C1.000
fabG11673853c.414A>C1.000
fabG11673856c.417T>C1.000
fabG11673865c.426C>G0.987
fabG11673870p.Ser144Met0.987
fabG11673901c.462A>G1.000
fabG11673904c.465C>G0.992
fabG11673905p.Ser156Ala1.000
fabG11673916c.477A>C1.000
fabG11673917p.Val160Leu1.000
fabG11673922c.483T>C1.000
fabG11673931c.492C>G0.992
fabG11673941p.Ala168Ser1.000
fabG11673946c.507C>G1.000
fabG11673955c.516G>C1.000
fabG11673961c.522A>C1.000
fabG11673962p.Asn175Gly0.983
fabG11673967c.528G>C0.983
fabG11673973c.534G>C0.983
fabG11673976c.537T>C0.983
fabG11673985c.546C>A1.000
fabG11673988c.549G>C0.988
fabG11674006p.Asp189Glu1.000
fabG11674098p.Val220Ala0.986
fabG11674114c.675T>A1.000
fabG11674123c.684T>C1.000
fabG11674132c.693T>C1.000
fabG11674136p.Ser233Ala1.000
fabG11674141c.702T>C1.000
fabG11674147c.708C>G0.966
fabG11674153c.714G>C0.969
fabG11674177c.738C>G0.993
inhA1674252c.51C>G1.000
inhA1674270c.69T>C1.000
inhA1674279c.78A>C1.000
inhA1674280p.Arg27Lys1.000
inhA1674285c.84A>G1.000
inhA1674295p.Gln32Ala1.000
inhA1674303c.102C>T1.000
inhA1674304p.Gln35Glu1.000
inhA1674321c.120G>C1.000
inhA1674331p.Leu44Met1.000
inhA1674334p.Arg45Lys1.000
inhA1674342c.141T>C1.000
inhA1674352p.Thr51Ala1.000
inhA1674361c.160C>T1.000
inhA1674366c.165G>C1.000
inhA1674367p.Ala56Lys1.000
inhA1674370p.Lys57Pro0.849
inhA1674384c.183C>G0.993
inhA1674396c.195G>C1.000
inhA1674399c.198A>G1.000
inhA1674402c.201C>T1.000
inhA1674421c.220T>C1.000
inhA1674428p.Gly76Asp1.000
inhA1674434p.Val78Ala1.000
inhA1674441c.240G>A1.000
inhA1674444c.243G>C1.000
inhA1674450c.249G>C1.000
inhA1674471c.270G>C1.000
inhA1674477c.276G>T1.000
inhA1674480c.279T>C1.000
inhA1674486c.285T>C1.000
inhA1674489c.288G>C1.000
inhA1674503p.Thr101Ser1.000
inhA1674507c.306G>C1.000
inhA1674514p.Ile105Val1.000
inhA1674534c.333G>C1.000
inhA1674542p.Ala114Glu1.000
inhA1674546c.345T>C1.000
inhA1674549c.348G>C1.000
inhA1674550p.Ser117Ala1.000
inhA1674576c.375T>C1.000
inhA1674582c.381T>C1.000
inhA1674585c.384T>C1.000
inhA1674589p.Met130Leu0.967
inhA1674597c.396G>A1.000
inhA1674600c.399G>A1.000
inhA1674606c.405G>T1.000
inhA1674610p.Ile137Val1.000
inhA1674619p.Pro140Glu1.000
inhA1674624c.423A>C1.000
inhA1674627c.426T>C1.000
inhA1674628p.Ser143Gly1.000
inhA1674656p.Ser152Thr1.000
inhA1674687c.486G>C1.000
inhA1674690c.489C>G1.000
inhA1674702c.501G>C1.000
inhA1674703c.502T>C1.000
inhA1674718c.517A>C1.000
inhA1674746p.Tyr182Phe1.000
inhA1674750c.549T>C1.000
inhA1674756c.555T>G1.000
inhA1674759c.558G>C1.000
inhA1674762c.561T>C1.000
inhA1674765c.564C>G1.000
inhA1674771c.570C>G1.000
inhA1674774c.573A>G1.000
inhA1674777c.576C>A1.000
inhA1674780c.579T>G1.000
inhA1674789c.588G>C1.000
inhA1674795c.594G>C1.000
inhA1674801c.600T>C1.000
inhA1674846p.Ile215Met1.000
inhA1674852c.651G>C1.000
inhA1674858c.657G>A1.000
inhA1674879c.678T>G1.000
inhA1674904p.Ala235Pro1.000
inhA1674930c.729C>T1.000
inhA1674942c.741T>C1.000
inhA1674954c.753G>C1.000
inhA1674957c.756G>C1.000
inhA1674966c.765T>C1.000
inhA1674967p.Asp256Thr1.000
rpsA1833539c.-3A>C1.000
rpsA1833541c.-1T>C1.000
rpsA1833547c.6G>A1.000
rpsA1833554p.Thr5Ser1.000
rpsA1833589c.48A>C1.000
rpsA1833595c.54T>G1.000
rpsA1833596p.Ser19Ala1.000
rpsA1833616c.75A>C1.000
rpsA1833619c.78A>C1.000
rpsA1833628c.87G>C1.000
rpsA1833634c.93G>A1.000
rpsA1833661c.120A>G1.000
rpsA1833664c.123C>A0.990
rpsA1833676c.135A>G1.000
rpsA1833679c.138G>T1.000
rpsA1833685c.144G>T1.000
rpsA1833694c.153G>C0.990
rpsA1833697c.156C>G1.000
rpsA1833703c.162C>T1.000
rpsA1833724c.183C>T1.000
rpsA1833727c.186G>C1.000
rpsA1833730c.189C>T1.000
rpsA1833733c.192C>T1.000
rpsA1833734p.Ala65Ser1.000
rpsA1833745c.204G>C1.000
rpsA1833787c.246C>G1.000
rpsA1833790c.249T>C1.000
rpsA1833793c.252C>T1.000
rpsA1833802c.261A>G1.000
rpsA1833808c.267G>C1.000
rpsA1833811c.270G>T1.000
rpsA1833829c.288A>G1.000
rpsA1833832c.291G>A1.000
rpsA1833838c.297G>C1.000
rpsA1833841c.300C>G1.000
rpsA1833847c.306C>G1.000
rpsA1833856c.315A>G1.000
rpsA1833859c.318C>G1.000
rpsA1833862c.321G>T1.000
rpsA1833874c.333T>C1.000
rpsA1833894p.Ala118Glu1.000
rpsA1833928c.387G>C1.000
rpsA1833949c.408T>C1.000
rpsA1833970c.429G>T1.000
rpsA1833976c.435C>T1.000
rpsA1833979c.438T>C0.991
rpsA1833985c.444G>C1.000
rpsA1833994c.453G>C1.000
rpsA1834000c.459G>C1.000
rpsA1834009c.468C>T1.000
rpsA1834012c.471G>T1.000
rpsA1834015c.474G>C1.000
rpsA1834021c.480C>T1.000
rpsA1834030c.489C>G1.000
rpsA1834097c.556T>A1.000
rpsA1834102c.561T>C1.000
rpsA1834123c.582C>T1.000
rpsA1834150c.609G>C1.000
rpsA1834153c.612T>C1.000
rpsA1834154p.Asn205Gln1.000
rpsA1834157c.616T>C1.000
rpsA1834162c.621A>G1.000
rpsA1834165c.624A>G1.000
rpsA1834169p.Thr210Ala1.000
rpsA1834177c.636A>C1.000
rpsA1834189c.648G>C1.000
rpsA1834213c.672G>C1.000
rpsA1834234c.693G>C1.000
rpsA1834240c.699T>C1.000
rpsA1834249c.708T>C1.000
rpsA1834261c.720A>G1.000
rpsA1834264c.723G>C1.000
rpsA1834279c.738C>T1.000
rpsA1834297c.756C>T0.991
rpsA1834303c.762T>G1.000
rpsA1834306c.765T>C1.000
rpsA1834330c.789C>G1.000
rpsA1834345c.804C>T1.000
rpsA1834348c.807T>C1.000
rpsA1834361c.820T>C1.000
rpsA1834366c.825A>G1.000
rpsA1834387c.846C>T1.000
rpsA1834396c.855G>T0.992
rpsA1834411c.870T>C1.000
rpsA1834423c.882G>T0.992
rpsA1834432c.891G>T1.000
rpsA1834451c.910T>C1.000
rpsA1834456c.915T>G1.000
rpsA1834468c.927A>G1.000
rpsA1834513c.972C>G1.000
rpsA1834520p.Ala327Ser1.000
rpsA1834528c.987T>C1.000
rpsA1834540c.999G>C1.000
rpsA1834543c.1002C>G1.000
rpsA1834546c.1005T>C1.000
rpsA1834606c.1065C>T1.000
rpsA1834609c.1068T>C1.000
rpsA1834619c.1078T>C1.000
rpsA1834622c.1081T>A1.000
rpsA1834633c.1092A>G1.000
rpsA1834639c.1098T>C1.000
rpsA1834667p.Ala376Ser1.000
rpsA1834690c.1149T>C1.000
rpsA1834732c.1191T>C1.000
rpsA1834738c.1197A>G1.000
rpsA1834753c.1212T>C1.000
rpsA1834756c.1215G>A1.000
rpsA1834759c.1218A>C1.000
rpsA1834765p.Glu408Asp1.000
rpsA1834774c.1233C>T0.987
rpsA1834776p.Ala412Glu1.000
rpsA1834780c.1239A>G1.000
rpsA1834786c.1245A>G1.000
rpsA1834789c.1248T>C1.000
rpsA1834792c.1251G>C1.000
rpsA1834829p.Ala430Thr1.000
rpsA1834852c.1311C>G1.000
rpsA1834945c.1404C>A1.000
rpsA1834954c.1413G>T1.000
rpsA1834957c.1416C>A1.000
tlyA1918278c.339C>G1.000
tlyA1918281c.342A>T1.000
tlyA1918290c.351G>A1.000
tlyA1918296c.357G>C1.000
tlyA1918300p.Ser121Pro1.000
tlyA1918476c.537A>G1.000
tlyA1918477p.Leu180Met1.000
tlyA1918485c.546G>A1.000
tlyA1918494c.555T>C1.000
tlyA1918629c.690G>T0.983
tlyA1918632c.693G>C1.000
tlyA1918635c.696C>A1.000
katG2155323c.789C>G0.636
katG2155601p.Cys171Val1.000
katG2155614c.498A>G1.000
katG2155617c.495A>G1.000
katG2155628p.Ala162Ser0.235
katG2155632c.480T>C1.000
katG2155637p.Leu159Ile1.000
katG2155640p.Lys158Gln0.606
katG2155661p.Val151Leu1.000
katG2155674c.438C>G0.865
katG2155680c.432C>G1.000
katG2155691c.421A>G1.000
katG2155696p.Ala139Val1.000
katG2155716c.396A>C1.000
katG2155722c.390C>G1.000
katG2155728c.384C>G1.000
katG2155742p.Gly124Arg1.000
katG2155743c.369C>T1.000
katG2155747p.Ala122Gly1.000
katG2155752c.360G>A1.000
katG2155766p.His116Glu1.000
katG2155769p.Ile115Val1.000
katG2155788c.324G>A0.981
katG2155796p.Ala106Ser1.000
katG2155805p.Ile103Val1.000
katG2155806c.306A>G1.000
katG2155815c.297C>A1.000
katG2155824c.288G>T1.000
katG2155828p.Tyr95Phe0.385
katG2155836c.276G>C0.324
pncA2289074p.Asp56Glu1.000
pncA2289095c.147G>A1.000
pncA2289104c.138T>G1.000
pncA2289194c.48A>G1.000
pncA2289200c.42G>A1.000
pncA2289206c.36G>A1.000
kasA2518219c.105T>C1.000
kasA2518222c.108G>C1.000
kasA2518223c.109T>C1.000
kasA2518231c.117C>A1.000
kasA2518234c.120G>A1.000
kasA2518534c.420G>C1.000
kasA2518564c.450C>G1.000
kasA2518567c.453G>C1.000
kasA2518573c.459G>C1.000
kasA2518574p.Ile154Ala1.000
kasA2518582c.468G>T1.000
kasA2518583p.Gln157Glu1.000
kasA2518588c.474T>C1.000
kasA2518591c.477G>C1.000
kasA2518606c.492G>C1.000
kasA2518609p.Met165Ile1.000
kasA2518612c.498C>G1.000
kasA2518621c.507G>A1.000
kasA2518624c.510C>G1.000
kasA2518636c.522C>A1.000
kasA2518639c.525G>T1.000
kasA2518642c.528A>G1.000
kasA2518645c.531G>C1.000
kasA2518656p.Ala181Gly1.000
kasA2518681c.567C>T1.000
kasA2518684c.570C>G1.000
kasA2518688p.Val192Phe1.000
kasA2518697p.Cys195Val1.000
kasA2518705c.591T>C1.000
kasA2518708c.594C>G1.000
kasA2518714c.600A>C1.000
kasA2518715p.Pro201Gly1.000
kasA2518732c.618C>G0.975
kasA2518747c.633C>G1.000
kasA2518756c.642G>C1.000
kasA2518777p.Asp221Glu1.000
kasA2518780p.Glu222Asp1.000
kasA2518783c.669T>C1.000
kasA2518785p.Glu224Ala1.000
kasA2518787p.Arg225Gly1.000
kasA2518795c.681C>T1.000
kasA2518816c.702C>T1.000
kasA2518822c.708C>A1.000
kasA2518825c.711T>C1.000
kasA2518843c.729T>C1.000
kasA2518847p.Leu245Met1.000
kasA2518853p.Leu247Ile1.000
kasA2518864c.750G>C1.000
kasA2518877p.Lys255Leu1.000
kasA2518898c.784T>C1.000
kasA2518903c.789C>T1.000
kasA2518906c.792A>G1.000
kasA2518907c.793T>C1.000
kasA2518910p.Leu266Met1.000
kasA2518915c.801T>C1.000
kasA2518936c.822C>G1.000
kasA2518939c.825T>C1.000
kasA2518942c.828T>C1.000
kasA2519041c.927C>T0.992
kasA2519044c.930G>C0.992
kasA2519056c.942G>C1.000
kasA2519059c.945G>C0.991
kasA2519062c.948T>G1.000
kasA2519068c.954C>T1.000
kasA2519072p.Ala320Thr1.000
kasA2519077c.963G>T0.991
kasA2519086c.972C>T0.991
kasA2519092c.978C>A0.989
kasA2519095c.981C>G0.989
kasA2519104c.990T>A0.985
kasA2519107c.993T>C1.000
kasA2519108p.Asp332Gln1.000
kasA2519111p.Gln333Asn0.985
kasA2519137c.1023T>G1.000
kasA2519140c.1026G>T1.000
kasA2519146c.1032C>T1.000
kasA2519158c.1044C>T1.000
kasA2519173c.1059C>G1.000
kasA2519185c.1071C>G1.000
kasA2519194c.1080G>C1.000
kasA2519195p.Thr361Ala1.000
kasA2519198c.1084C>T1.000
kasA2519209c.1095C>G1.000
kasA2519218c.1104G>T1.000
kasA2519224c.1110C>G1.000
kasA2519242c.1128C>G1.000
kasA2519248c.1134C>T1.000
kasA2519257c.1143C>T1.000
kasA2519260c.1146T>C1.000
kasA2519263c.1149C>T1.000
kasA2519266c.1152C>G1.000
kasA2519269c.1155C>T1.000
kasA2519272c.1158C>G1.000
kasA2519278c.1164A>G1.000
kasA2519281c.1167G>T1.000
kasA2519284c.1170C>T1.000
kasA2519293c.1179T>C1.000
kasA2519297p.Arg395Lys1.000
kasA2519305c.1191A>C1.000
kasA2519306p.Val398Ile1.000
kasA2519344c.1230G>C1.000
kasA2519347c.1233T>G1.000
folC2746537c.1062G>A1.000
folC2746540c.1059C>T1.000
folC2746543c.1056G>T1.000
folC2746555c.1044C>A1.000
folC2746561c.1038G>T1.000
folC2746564c.1035T>C1.000
folC2746576c.1023G>A1.000
folC2746702c.897C>G1.000
folC2746708c.891G>A1.000
folC2746711c.888T>C1.000
folC2746720c.879C>T1.000
folC2746728c.871A>G1.000
folC2746730p.Tyr290Phe1.000
folC2746744c.855A>C1.000
folC2746813c.786T>C1.000
folC2746819c.780A>G1.000
folC2746825c.774C>G1.000
folC2746836p.Ser255Ala1.000
folC2746840c.759G>A1.000
folC2746849c.750C>G1.000
folC2746854p.Ser249Ala1.000
folC2746855c.744T>C1.000
folC2746858c.741G>T1.000
folC2746960c.639G>C0.500
folC2746967p.Gly211Glu0.467
folC2747007p.Ser198Gly1.000
folC2747020c.579G>C1.000
folC2747023c.576G>C1.000
folC2747029c.570C>G1.000
folC2747032c.567T>G1.000
folC2747035c.564G>A1.000
folC2747040p.Ile187Val1.000
folC2747041c.558C>G1.000
folC2747059c.540A>G1.000
folC2747062c.537T>C1.000
folC2747074c.525C>G1.000
folC2747089c.510C>G1.000
folC2747097p.Val168Ile1.000
folC2747102p.Ala166Val1.000
folC2747107c.492C>G1.000
folC2747110c.489A>G1.000
folC2747134c.465G>C1.000
folC2747263c.336G>T1.000
folC2747275c.324A>G1.000
folC2747281c.318T>C1.000
folC2747289p.Pro104Ala1.000
folC2747290c.309T>C1.000
folC2747302c.297T>C1.000
folC2747305c.294G>A1.000
folC2747314c.285T>G1.000
folC2747323c.276G>A1.000
folC2747335c.264C>G1.000
folC2747339p.Thr87Ile1.000
folC2747343p.Val86Leu1.000
folC2747355p.Val82Ile1.000
folC2747356p.Met81Ile1.000
folC2747362c.237C>T1.000
folC2747365c.234C>G1.000
folC2747371c.228G>C1.000
thyX3067325c.621T>C1.000
thyX3067340c.606C>T1.000
thyX3067349c.597C>G1.000
thyX3067355c.591T>C1.000
thyX3067364c.582G>A1.000
thyX3067367c.579C>A1.000
thyX3067376c.570C>G1.000
thyX3067379c.567G>A1.000
thyX3067389p.Thr186Ser1.000
thyX3067391c.555C>G1.000
thyX3067406c.540T>C1.000
thyX3067418c.528G>C1.000
thyX3067430c.516G>C1.000
thyX3067439c.507T>C1.000
thyX3067444c.502G>T1.000
thyX3067454c.492G>A1.000
thyX3067457c.489G>C1.000
thyX3067465p.Ile161Val1.000
thyX3067466c.480C>G1.000
thyX3067474p.Pro158Ser1.000
thyX3067481c.465G>C1.000
thyX3067490c.456G>C1.000
thyX3067501p.Lys149Arg1.000
thyX3067503p.Ala148Gly1.000
thyX3067511c.435C>T1.000
thyX3067515p.Ser144Thr1.000
thyX3067526c.420G>C1.000
thyX3067531p.Ala139Ser0.769
thyX3067631c.315G>C1.000
thyX3067661c.285G>C1.000
thyX3067669c.277G>A0.964
thyX3067681p.Cys89Ala0.957
thyX3067685c.261T>C1.000
thyX3067688c.258C>G0.959
thyX3067711c.235C>G0.949
thyX3067712c.234C>G0.951
thyX3067718c.228G>C1.000
thyX3067727c.219T>G1.000
thyX3067730c.216C>G0.977
thyX3067739c.207A>G0.978
thyX3067760c.186C>G0.967
thyX3067765p.Leu61Ile1.000
thyX3067771p.Gly59Ser0.975
thyX3067772c.174G>C1.000
thyX3067781c.165G>C1.000
thyX3067788p.Lys53Arg0.962
thyX3067793c.153A>G1.000
thyX3067802c.144G>C1.000
thyX3067814c.132A>G1.000
thyX3067820c.126G>A0.955
thyX3067840p.Val36Thr0.846
thyX3067841c.105C>G0.846
thyX3067850c.96T>A0.250
thyX3067856p.Asp30Glu0.700
thyX3067916c.30T>C0.956
thyX3067935p.Thr4Ile1.000
thyA3073839c.633A>G1.000
thyA3073863c.609A>G1.000
thyA3073874p.Ile200Val1.000
thyA3073890p.Leu194Phe1.000
thyA3073902c.570G>C1.000
thyA3073920c.552G>C1.000
thyA3073925c.547A>G1.000
thyA3073926c.546C>A0.991
thyA3073929c.543A>G1.000
thyA3073959c.513A>G1.000
thyA3073977c.495T>C1.000
thyA3073983c.489G>C0.988
thyA3073989c.483A>G1.000
thyA3073994c.478C>G1.000
thyA3073997c.475G>A1.000
thyA3074000p.Arg158Lys1.000
thyA3074004c.468A>G1.000
thyA3074013c.459G>A1.000
thyA3074151c.321C>T1.000
thyA3074160c.312T>C1.000
thyA3074165p.Ala103Thr1.000
thyA3074175c.297T>C1.000
thyA3074181c.291T>C0.975
thyA3074184c.288T>C1.000
thyA3074187c.285A>G1.000
thyA3074196c.276C>G1.000
thyA3074199c.273C>G1.000
thyA3074205p.Glu89Asp1.000
thyA3074214p.Asp86Glu1.000
thyA3074220c.252T>G1.000
thyA3074238c.234G>C1.000
thyA3074244c.228T>A1.000
thyA3074250p.Glu74Asp1.000
thyA3074264p.Gly70Arg1.000
thyA3074267p.Ile69Val1.000
thyA3074268c.204A>G1.000
thyA3074285c.187A>G1.000
thyA3074286c.186A>G1.000
thyA3074298c.174C>T1.000
ald3086870c.51C>G0.833
ald3086882c.63C>T0.833
ald3086885c.66C>G1.000
ald3086888c.69C>G1.000
ald3086894c.75A>G1.000
ald3086897c.78A>G1.000
ald3086903c.84T>C1.000
ald3086906c.87T>C1.000
ald3086912c.93T>C1.000
ald3086919p.Leu34Ile1.000
ald3086930c.111A>C1.000
ald3086933c.114T>G1.000
ald3086939c.120A>T1.000
ald3086945c.126C>G1.000
ald3087179c.360C>G1.000
ald3087191c.372C>T1.000
ald3087197c.378A>C1.000
ald3087200c.381A>G1.000
ald3087203c.384C>G1.000
ald3087209c.390T>G1.000
ald3087221c.402C>T1.000
ald3087224c.405A>G1.000
ald3087233c.414T>A1.000
ald3087272c.453A>C1.000
ald3087278c.459A>G1.000
ald3087281c.462G>C1.000
ald3087284c.465C>G1.000
ald3087290c.471T>C1.000
ald3087302c.483C>T1.000
ald3087314c.495C>T1.000
ald3087319p.Glu167Ala1.000
ald3087329p.Asp170Glu0.913
ald3087368c.549A>C1.000
ald3087371c.552C>A1.000
ald3087383p.Asn188Lys1.000
fbiA3640319c.-224A>G1.000
fbiA3640320c.-223G>T1.000
fbiA3640337c.-206T>C1.000
fbiA3640701p.Ile53Met1.000
fbiA3640707c.165G>C1.000
fbiA3640708p.Leu56Val1.000
fbiA3640713c.171T>G1.000
fbiA3640714p.Val58Ile1.000
fbiA3640722c.180G>C1.000
fbiA3640725c.183T>C1.000
fbiA3640728c.186G>C1.000
fbiA3640743c.201T>C1.000
fbiA3640878c.336T>C1.000
fbiA3640884c.342G>C1.000
fbiA3640901p.Gln120Arg1.000
fbiA3640914c.372C>G1.000
fbiA3640915c.373C>T1.000
fbiA3640924p.Ile128Val1.000
fbiA3641046c.504T>C1.000
fbiA3641055c.513G>A1.000
fbiA3641073c.531T>C1.000
fbiA3641076c.534C>G0.982
fbiA3641475c.933C>G1.000
panD4044213c.69G>C1.000
embC4240420c.558T>C1.000
embC4240423c.561G>A1.000
embC4240427p.Ser189Gly1.000
embC4240444c.582C>G1.000
embC4240459c.597G>C1.000
embC4240462c.600G>C1.000
embC4240471c.609C>T1.000
embC4240475p.Ala205Ser1.000
embC4240630c.768C>T1.000
embC4240631p.Met257Val1.000
embC4240645c.783G>C1.000
embC4240654c.792C>A1.000
embC4240655p.Ala265Pro1.000
embC4240717c.855T>C1.000
embC4240726c.864G>C1.000
embC4240783c.921G>C1.000
embC4240789c.927T>C1.000
embC4240819c.957A>C1.000
embC4240825c.963G>A1.000
embC4240831c.969T>G1.000
embC4240837c.975C>T0.993
embC4240867c.1005T>C1.000
embC4240870c.1008T>C1.000
embC4240874c.1012A>T1.000
embC4240879c.1017G>C1.000
embC4240880p.Ala340Asn1.000
embC4240885c.1023T>C1.000
embC4240886p.Ile342Val1.000
embC4240897c.1035C>G1.000
embC4240910p.Ala350Leu1.000
embC4240918c.1056G>A1.000
embC4240921c.1059C>G1.000
embC4240922p.Thr354Ala1.000
embC4240936c.1074A>G1.000
embC4240981c.1119G>C0.973
embC4240983p.Ser374Asn1.000
embC4240987c.1125G>C1.000
embC4240990c.1128A>C1.000
embC4240996c.1134G>C1.000
embC4241002c.1140G>C1.000
embC4241008c.1146G>C1.000
embC4241017c.1155T>C1.000
embC4241023c.1161T>G1.000
embC4241024p.Val388Phe1.000
embC4241038c.1176G>C1.000
embC4241039p.Asp393Asn1.000
embC4241050c.1188T>G1.000
embC4241053c.1191G>C1.000
embC4241059c.1197G>A1.000
embC4241074c.1212G>C1.000
embC4241095c.1233C>T1.000
embC4241104c.1242G>A1.000
embC4241107c.1245G>C1.000
embC4241109p.Ala416Gly1.000
embC4241121p.Ser420Asn1.000
embC4241126p.Leu422Met1.000
embC4241407c.1545A>G1.000
embC4241420p.Glu520Ser1.000
embC4241521c.1659T>C1.000
embC4241533c.1671T>C1.000
embC4241536c.1674A>C1.000
embC4241539c.1677T>C1.000
embC4241545c.1683T>C1.000
embC4241548c.1686T>C1.000
embC4241551c.1689A>T1.000
embC4241560c.1698C>G1.000
embC4241584c.1722T>C1.000
embC4241587c.1725C>G1.000
embC4241593c.1731C>G1.000
embC4241614c.1752A>C1.000
embC4241626c.1764T>C1.000
embC4241635c.1773G>C1.000
embC4241644c.1782G>C0.989
embC4241648c.1786T>C0.989
embC4241656c.1794G>A1.000
embC4241659c.1797G>C1.000
embC4241662c.1800G>C1.000
embC4241665c.1803G>C1.000
embC4241668c.1806G>C1.000
embC4241671c.1809T>G1.000
embC4241791c.1929G>C1.000
embC4241809c.1947A>G1.000
embC4242025c.2163A>C1.000
embC4242036p.Gln725Leu1.000
embC4242045p.Ile728Thr1.000
embC4242047p.Ser729Ala1.000
embC4242061c.2199G>C1.000
embC4242119p.Glu753Asn1.000
embC4242232c.2370T>C1.000
embC4242236p.Ala792Ser1.000
embC4242245p.Thr795Ser1.000
embC4242370c.2508C>G1.000
embC4242373c.2511C>T1.000
embC4242386p.Asn842Gly1.000
embC4242391c.2529G>C1.000
embC4242401p.Arg847Thr1.000
embC4242406c.2544A>C1.000
embC4242415c.2553G>C1.000
embC4242427c.2565A>G1.000
embC4242622c.2760C>G1.000
embC4242625c.2763T>C1.000
embC4242631c.2769G>C1.000
embC4242652c.2790C>G1.000
embC4242655c.2793A>C1.000
embC4242658c.2796A>G1.000
embC4242659p.Leu933Met1.000
embC4242662p.Ser934Ala1.000
embC4242689p.Val943Ile1.000
embC4242694c.2832G>C1.000
embC4242715c.2853T>C0.964
embC4242806p.Phe982Leu1.000
embC4242820c.2958G>C1.000
embC4242832c.2970A>G1.000
embC4242838c.2976C>G1.000
embC4242844c.2982A>G1.000
embC4242847c.2985C>A1.000
embC4242855p.Gly998Ala1.000
embC4242862c.3000A>G1.000
embC4242872p.Asp1004Thr1.000
embC4242878p.Thr1006Val1.000
embC4242907c.3045G>C1.000
embC4242919c.3057A>G1.000
embC4242928c.3066A>G1.000
embC4242940c.3078T>C1.000
embC4242941p.His1027Tyr1.000
embC4242944p.Asn1028Leu1.000
embC4242968p.Thr1036Ser1.000
embC4242973c.3111G>A1.000
embC4242980p.Met1040Leu1.000
embA4243811c.579T>C1.000
embA4243817c.585T>C1.000
embA4244189c.957C>G1.000
embA4244207c.975C>G1.000
embA4244208p.Leu326Val1.000
embA4244340p.Ser370Ala1.000
embA4244349p.Leu373Phe1.000
embA4244366c.1134C>A0.980
embA4244372c.1140T>C1.000
embA4244378c.1146G>A1.000
embA4244657c.1425G>C1.000
embA4244669c.1437G>C1.000
embA4244675c.1443A>G1.000
embA4244681c.1449A>C1.000
embA4244684c.1452C>G1.000
embA4244694p.Lys488Ala1.000
embA4244712p.Ala494Ser1.000
embA4244726p.Asp498Glu1.000
embA4244747c.1515T>G1.000
embA4244878p.Ala549Val1.000
embA4244883c.1651C>A1.000
embA4244889p.Ile553Leu1.000
embA4244894c.1662C>T1.000
embA4244897c.1665T>C1.000
embA4244900c.1668G>C1.000
embA4244904p.Val558Ile1.000
embA4244921c.1689C>G0.460
embA4244922p.Thr564His0.460
embA4244930c.1698G>C0.989
embA4244933c.1701A>G1.000
embA4244945c.1713C>T0.991
embA4244960c.1728A>G1.000
embA4245042p.Thr604Ala1.000
embA4245047c.1815G>C1.000
embA4245053c.1821G>C1.000
embA4245059c.1827G>C1.000
embA4245060c.1828T>C1.000
embA4245074c.1842G>C1.000
embA4245077c.1845G>C1.000
embA4245083c.1851A>C1.000
embA4245086c.1854C>G1.000
embA4245089c.1857G>C1.000
embA4245101c.1869G>C1.000
embA4245125c.1893G>C1.000
embA4245233c.2001G>C1.000
embA4245236p.Met668Ile1.000
embA4245449c.2217G>C1.000
embA4245454p.Ala741Val1.000
embA4245459p.Pro743Ala1.000
embA4245465p.Pro745Thr1.000
embA4245470c.2238T>C1.000
embA4245473c.2241C>G1.000
embA4245488c.2256G>C1.000
embA4245905c.2673C>G1.000
embA4246004c.2772T>C1.000
embA4246010c.2778G>T0.982
embA4246013c.2781T>C0.982
embA4246041p.Asp937Asn1.000
embA4246049c.2817G>C1.000
embA4246055c.2823T>C1.000
embA4246062p.Tyr944Asp1.000
embA4246164c.2932T>C1.000
embA4246181c.2949C>T1.000
embA4246184c.2952A>C1.000
embA4246187c.2955C>G1.000
embA4246190c.2958C>T1.000
embA4246205c.2973A>G1.000
embA4246211c.2979T>C1.000
embA4246319c.3087G>C1.000
embA4246325c.3093G>C1.000
embA4246330p.Thr1033Ile1.000
embA4246349c.3117C>G1.000
embB4246642c.129G>C1.000
embB4246645c.132G>C1.000
embB4246660c.147C>G1.000
embB4246862p.Val117His1.000
embB4246869p.Ser119Asn1.000
embB4246874p.Gln121Lys1.000
embB4246877p.Arg122Ser0.985
embB4246882c.369G>C1.000
embB4247034p.Ser174Thr1.000
embB4247042p.Pro177Ala1.000
embB4247050c.537C>G1.000
embB4247062c.549G>T1.000
embB4247068c.555T>C1.000
embB4247074c.561G>C1.000
embB4247077c.564G>C1.000
embB4247086p.Asp191Glu1.000
embB4247091p.Thr193Ser1.000
embB4247380c.867C>G1.000
embB4247386c.873T>C1.000
embB4247387p.Val292Ile1.000
embB4247401c.888T>C1.000
embB4247407c.894G>C1.000
embB4247420p.Ile303Leu1.000
embB4247424c.913 915del1.000
embB4247434c.921C>G1.000
embB4247437c.924A>G1.000
embB4247440c.927C>G1.000
embB4247467c.954C>T1.000
embB4247470c.957T>C1.000
embB4247491c.978G>T1.000
embB4247497c.984T>C1.000
embB4247506c.993C>T1.000
embB4247512c.999T>C1.000
embB4247527c.1014G>C1.000
embB4247536c.1023C>G1.000
embB4247539c.1026T>C1.000
embB4247540p.Val343Ile1.000
embB4247555p.Leu348Ile1.000
embB4247566c.1053C>G1.000
embB4247572c.1059A>C1.000
embB4247590c.1077A>C1.000
embB4247611c.1098G>C1.000
embB4247621c.1108C>T1.000
embB4247629c.1116C>G1.000
embB4247638c.1125G>C1.000
embB4247761c.1248T>C1.000
embB4247866c.1353G>C0.926
embB4247869c.1356G>C0.890
embB4247887c.1374C>T0.945
embB4247893c.1380C>T1.000
embB4247899p.Met462Ile1.000
embB4247905c.1392G>C1.000
embB4247909c.1396T>C1.000
embB4247965c.1452C>G1.000
embB4247968c.1455C>A1.000
embB4247974c.1461C>A1.000
embB4247977c.1464C>G0.957
embB4248007c.1494C>G0.993
embB4248008c.1495C>T1.000
embB4248011p.Ser500Ala1.000
embB4248020p.Leu503Met1.000
embB4248034c.1521G>A1.000
embB4248035p.Val508Ile1.000
embB4248041p.Ala510Thr1.000
embB4248044p.Lys511Ala1.000
embB4248052c.1539G>T1.000
embB4248055c.1542G>C1.000
embB4248056p.Ser515Ala1.000
embB4248063p.Ala517Glu1.000
embB4248070c.1557T>C1.000
embB4248085c.1572T>C1.000
embB4248094c.1581C>T0.990
embB4248097c.1584C>G1.000
embB4248106c.1593C>G0.975
embB4248118c.1605T>C0.975
embB4248130c.1617G>C1.000
embB4248142c.1629T>C1.000
embB4248143p.Leu544Ile1.000
embB4248157c.1644A>G1.000
embB4248158p.Cys549Ser0.983
embB4248167p.Thr552Ala0.984
embB4248170p.Ala553Ser0.976
embB4248173p.Val554Leu0.969
embB4248199c.1686A>G1.000
embB4248200p.Ile563Val1.000
embB4248206p.Ser565Gly1.000
embB4248220c.1707A>G1.000
embB4248225p.Ala571Val0.992
embB4248233c.1720C>T0.993
embB4248242p.Val577Ile0.993
embB4248252p.Gly580Ala0.992
embB4248256c.1743C>G0.992
embB4248259p.Met582Ile0.992
embB4248269p.Met586Gln0.990
embB4248275p.Thr588Ala0.990
embB4248304c.1791G>C1.000
embB4248316c.1803C>G1.000
embB4248319c.1806A>G1.000
embB4248322c.1809G>C1.000
embB4248338p.Leu609Val1.000
embB4248457c.1944T>C1.000
embB4248460c.1947C>G1.000
embB4248472c.1959T>C1.000
embB4248478c.1965G>C1.000
embB4249469p.Leu986Met1.000
embB4249483c.2970C>G1.000
embB4249486c.2973T>C1.000
embB4249487p.Leu992Met1.000
embB4249594c.3081G>C1.000
embB4249600c.3087A>G1.000
embB4249608p.Thr1032Ile1.000
embB4249624c.3111C>G1.000
embB4249627c.3114G>C1.000
embB4249632p.Thr1040Ser1.000
embB4249643c.3130C>T1.000
embB4249657c.3144C>G1.000
ethA4326577c.897G>A0.938
ethA4326587p.Val296Ala0.939
ethA4326597p.Leu293Val1.000
ethA4326603p.Gln291Glu1.000
ethA4326604c.870G>A1.000
ethA4326610c.864G>C1.000
ethA4326620p.His285Arg1.000
ethA4326627p.Gly283Ser1.000
ethA4326847c.627G>C0.319
ethA4326865c.609C>G0.229
ethA4326868c.606G>C1.000
ethA4326943p.Asn177Lys1.000
ethA4326950p.Ala175Gly1.000
ethA4326954p.Asp174Lys1.000
ethA4326985c.489A>G1.000
ethA4327036c.438G>A1.000
ethA4327060c.414G>A0.565
ethA4327390c.84C>G1.000
ethA4327401p.Asp25Asn1.000
ethA4327405c.69C>T1.000
ethA4327419p.Ala19Thr1.000
gid4408253c.-51A>G1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;