TB-Profiler result

Run: SRR5485484
Summary

Run ID: SRR5485484

Sample name:

Date: 18-08-2022 08:29:05

Number of reads: 126392

Percentage reads mapped: 99.23

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761110 p.Asp435Val missense_variant 1.0 rifampicin
pncA 2289248 c.-7T>C upstream_gene_variant 0.2 pyrazinamide
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.29
rrs 1472531 n.686A>G non_coding_transcript_exon_variant 0.18
pncA 2288924 p.Phe106Leu missense_variant 0.27
embB 4247348 p.Thr279Pro missense_variant 0.22