TB-Profiler result

Run: SRR5485565
Summary

Run ID: SRR5485565

Sample name:

Date: 18-08-2022 08:25:54

Number of reads: 91515

Percentage reads mapped: 96.92

Strain:

Drug-resistance: RR-TB

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
rpoB 761155 p.Ser450Leu missense_variant 1.0 rifampicin
rpsL 781687 p.Lys43Arg missense_variant 1.0 streptomycin
embB 4247429 p.Met306Leu missense_variant 1.0 ethambutol
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rrs 1472302 n.457G>C non_coding_transcript_exon_variant 0.23
rrs 1472493 n.648T>G non_coding_transcript_exon_variant 0.22
rrs 1472674 n.829T>C non_coding_transcript_exon_variant 0.15
rrs 1472719 n.874G>A non_coding_transcript_exon_variant 0.14
rrs 1473227 n.1384delT non_coding_transcript_exon_variant 0.18
embB 4247618 p.Val369Met missense_variant 0.14