TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
Back to results page.
Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5ccbf3525f98e
Sample: 5ccbf3525f98e

Download results

Summary
ID: 5ccbf3525f98e
Date: Fri May 3 08:55:25 2019
Strain: lineage4.1.2;lineage4.3.3;lineage1.2.2
Drug-resistance: Sensitive

Drug1ResistanceSupporting Mutations (frequency)
Isoniazid
Rifampicin
Ethambutol
Pyrazinamide
Streptomycin
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage1.2.2Indo-OceanicEAI1RD239

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5803c.564A>G1.000
gyrB5807p.Val190Ile0.953
gyrB5819c.580C>T0.595
gyrB5824c.585A>G0.610
gyrB5848c.609G>C1.000
gyrB5858p.Asn207Glu1.000
gyrB6086p.Thr283Pro1.000
gyrB6097c.858G>A1.000
gyrB6100c.861G>C1.000
gyrB6109c.870G>C1.000
gyrB6115c.876A>G1.000
gyrB6123p.Ala295Gly1.000
gyrB6127c.888G>T1.000
gyrB6130c.891T>C1.000
gyrB6133c.894G>C1.000
gyrB6175c.936G>A1.000
gyrB6181c.942C>A1.000
gyrB6184c.945C>T1.000
gyrB6196c.957C>T1.000
gyrB6265c.1026C>T1.000
gyrB6277c.1038C>T1.000
gyrB6283p.Asp348Glu1.000
gyrB6286c.1047T>C1.000
gyrB6292c.1053G>C1.000
gyrB6295c.1056A>G1.000
gyrB6298c.1059C>T1.000
gyrB6307c.1068T>G1.000
gyrB6319c.1080G>C0.300
gyrB6329p.Glu364Gln0.222
gyrB6346c.1107C>T1.000
gyrB6352c.1113C>G1.000
gyrB6358c.1119C>G1.000
gyrB6361c.1122G>A1.000
gyrB6362c.1123T>C1.000
gyrB6382c.1143A>G1.000
gyrB6388c.1149T>C1.000
gyrB6391c.1152G>C1.000
gyrB6398p.Val387Ile1.000
gyrB6403c.1164T>C1.000
gyrB6523c.1284G>C1.000
gyrB6526c.1287T>C1.000
gyrB6532c.1293C>T1.000
gyrB6547c.1308T>C1.000
gyrB6550c.1311A>T1.000
gyrB6551c.1312T>C1.000
gyrB6571c.1332T>C1.000
gyrB6577c.1338T>C1.000
gyrB6583c.1344G>C1.000
gyrB6590p.Arg451Ser1.000
gyrB6601c.1362A>G1.000
gyrB6607c.1368T>C1.000
gyrB6610c.1371C>G1.000
gyrB6613c.1374A>G1.000
gyrB6616c.1377A>G1.000
gyrB6628c.1389C>A1.000
gyrB6634c.1395T>C1.000
gyrB6637c.1398T>G1.000
gyrB6640c.1401A>C1.000
gyrB6643c.1404A>G1.000
gyrB6649c.1410T>C1.000
gyrB6655c.1416T>C1.000
gyrB6673c.1434A>C1.000
gyrB6676c.1437T>G1.000
gyrB6685c.1446C>A0.978
gyrB6700c.1461T>C1.000
gyrB6703c.1464G>C1.000
gyrB6706c.1467G>A1.000
gyrB6709c.1470A>G1.000
gyrB6712c.1473G>C1.000
gyrB6727c.1488G>T0.975
gyrB6728c.1489C>T1.000
gyrB6745c.1506T>C1.000
gyrB6751c.1512G>C1.000
gyrB6760c.1521G>C1.000
gyrB6769c.1530C>T1.000
gyrB6775c.1536G>C1.000
gyrB6793c.1554T>C1.000
gyrB6797p.Gly520Thr1.000
gyrB6808c.1569C>T1.000
gyrB6811c.1572C>T1.000
gyrB6838c.1599C>G1.000
gyrB6841c.1602T>C1.000
gyrB6844c.1605T>G1.000
gyrB6853c.1614A>G1.000
gyrB6856c.1617T>C1.000
gyrB6859c.1620T>C1.000
gyrB6869c.1630T>C1.000
gyrB6872c.1633T>C1.000
gyrB6878c.1639T>C1.000
gyrB6881c.1642T>C1.000
gyrB6896p.Arg553Lys1.000
gyrB6910c.1671G>A1.000
gyrB6911p.Asn558His1.000
gyrB6916c.1677G>C1.000
gyrB6919c.1680T>C1.000
gyrB6925c.1686T>C1.000
gyrB6926c.1687T>C1.000
gyrB6931c.1692A>C1.000
gyrB6934c.1695A>G1.000
gyrB6952c.1713C>G1.000
gyrB6955c.1716G>A1.000
gyrB6966c.1728 1728del1.000
gyrA7343c.42G>T1.000
gyrA7355c.54T>C1.000
gyrA7362p.Glu21Gln1.000
gyrA7382c.81C>T1.000
gyrA7391c.90C>T1.000
gyrA7394c.93T>C1.000
gyrA7397c.96G>C1.000
gyrA7406c.105G>C1.000
gyrA7412c.111C>G1.000
gyrA7433c.132G>A1.000
gyrA7442c.141G>C1.000
gyrA7457c.156T>C1.000
gyrA7463c.162G>C1.000
gyrA7472c.171T>C1.000
gyrA7475c.174A>G1.000
gyrA7480p.Phe60Tyr1.000
gyrA7484c.183T>C1.000
gyrA7499c.198G>C1.000
gyrA7526c.225G>C1.000
gyrA7532c.231T>G1.000
gyrA7541c.240C>G1.000
gyrA7547c.246C>T1.000
gyrA7565c.264C>T1.000
gyrA7569p.Ala90Ser0.966
gyrA7585p.Ser95Thr1.000
gyrA7592c.291G>C1.000
gyrA7595c.294C>G1.000
gyrA7607c.306C>G1.000
gyrA7613c.312G>A1.000
gyrA7622c.321C>T1.000
gyrA7631c.330G>C1.000
gyrA7637c.336C>T1.000
gyrA7652c.351C>T1.000
gyrA7658c.357A>G1.000
gyrA7661c.360C>T1.000
gyrA7664c.363T>C1.000
gyrA7667c.366C>T1.000
gyrA7670c.369A>G1.000
gyrA7673c.372G>A1.000
gyrA7676c.375G>C1.000
gyrA7679c.378G>C1.000
gyrA7683c.382A>C1.000
gyrA7694c.393A>G1.000
gyrA7697c.396C>G1.000
gyrA7706c.405C>T1.000
gyrA7709c.408G>C1.000
gyrA7710c.409T>C1.000
gyrA7728c.427A>C1.000
gyrA7763c.462T>G1.000
gyrA7775c.474C>T1.000
gyrA7784c.483A>G1.000
gyrA7790c.489G>C1.000
gyrA7796c.495G>T1.000
gyrA7799c.498A>G1.000
gyrA7802c.501C>G1.000
gyrA7832c.531G>T1.000
gyrA7835c.534A>G1.000
gyrA7841c.540C>T1.000
gyrA7847c.546G>C1.000
gyrA7859c.558A>C1.000
gyrA7865c.564T>C1.000
gyrA7886c.585T>G1.000
gyrA8156c.855T>C1.000
gyrA8168c.867A>G1.000
gyrA8174c.873C>G1.000
gyrA8177c.876A>C1.000
gyrA8191p.Ala297Gly1.000
gyrA8198c.897T>C1.000
gyrA8207c.906T>C1.000
gyrA8210c.909G>A1.000
gyrA8219c.918T>C1.000
gyrA8222c.921C>T1.000
gyrA8225c.924T>C1.000
gyrA8235c.934T>C1.000
gyrA8240c.939C>A1.000
gyrA8246c.945C>G1.000
gyrA8247p.Ile316Val1.000
gyrA8253p.Ile318Leu1.000
gyrA8267c.966G>C1.000
gyrA8283p.Ile328Leu1.000
gyrA8288c.987T>C1.000
gyrA8294c.993T>C1.000
gyrA8315c.1014G>A1.000
gyrA8324c.1023T>C1.000
gyrA8327c.1026C>G1.000
gyrA8339c.1038A>G1.000
gyrA8340p.Ala347Ser1.000
gyrA8354c.1053G>C1.000
gyrA8357c.1056G>A1.000
gyrA8366c.1065G>C1.000
gyrA8372c.1071G>T1.000
gyrA8390c.1089C>G1.000
gyrA8391p.Tyr364Leu1.000
gyrA8399c.1098T>G1.000
gyrA8405c.1104C>T0.933
gyrA8408c.1107A>G1.000
gyrA8414c.1113C>T1.000
gyrA8420c.1119T>C1.000
gyrA8433p.Thr378Arg1.000
gyrA8442c.1141C>T1.000
gyrA8453c.1152A>C1.000
gyrA8456c.1155C>T1.000
gyrA8459c.1158G>A1.000
gyrA8462c.1161A>G1.000
gyrA8471c.1170T>C1.000
gyrA8477c.1176C>T1.000
gyrA8480c.1179C>T1.000
gyrA8486c.1185T>C1.000
gyrA8504c.1203G>C1.000
gyrA8513c.1212C>G1.000
gyrA8516c.1215T>C1.000
gyrA8519c.1218A>G1.000
gyrA8520c.1219C>T1.000
gyrA8535p.Glu412Gln1.000
gyrA8546p.Asp415Glu1.000
gyrA8561c.1260A>C1.000
gyrA8571c.1270C>T1.000
gyrA8603c.1302A>C1.000
gyrA8619c.1318T>C1.000
gyrA8624c.1323G>C1.000
gyrA8627c.1326C>G1.000
gyrA8633c.1332C>T1.000
gyrA8636c.1335A>C1.000
gyrA8645c.1344C>A1.000
gyrA8649p.Arg450Lys1.000
gyrA8655p.Ile452Val1.000
gyrA8663c.1362C>T1.000
gyrA8672c.1371A>G1.000
gyrA8678c.1377G>A0.971
gyrA8696c.1395G>C1.000
gyrA8699c.1398A>G1.000
gyrA8705c.1404C>T1.000
gyrA8711c.1410A>C1.000
gyrA8714c.1413A>G1.000
gyrA8723c.1422G>C1.000
gyrA8726c.1425G>A1.000
gyrA8731p.Gly477Ala1.000
gyrA8740p.Arg480His1.000
gyrA8744c.1443C>T1.000
gyrA8780c.1479C>T1.000
gyrA8783c.1482G>T0.941
gyrA8786c.1485T>G1.000
gyrA8796p.Ile499Val1.000
gyrA8799p.Ala500Pro1.000
gyrA8810c.1509A>T1.000
gyrA8813p.Asp504Glu1.000
gyrA8816c.1515C>G1.000
gyrA8828c.1527T>C1.000
gyrA8829c.1528T>C1.000
gyrA8837c.1536C>G1.000
gyrA8840c.1539C>T1.000
gyrA8852c.1551T>C1.000
gyrA8858c.1557T>G1.000
gyrA8867c.1566A>G1.000
gyrA8870c.1569G>C1.000
gyrA8873c.1572A>G1.000
gyrA8876c.1575C>T1.000
gyrA8897c.1596T>C1.000
gyrA8903c.1602T>C1.000
gyrA8915c.1614A>G1.000
gyrA8939c.1638T>C1.000
gyrA8942c.1641G>C1.000
gyrA8945c.1644G>A1.000
gyrA8946c.1645T>C1.000
gyrA8952p.Gln551Ala1.000
gyrA8967p.Ala556Asn1.000
gyrA8981c.1680G>C1.000
gyrA8987c.1686C>G1.000
gyrA8996c.1695T>C1.000
gyrA8998p.Leu566Trp1.000
gyrA9017c.1716C>G1.000
gyrA9023c.1722A>C1.000
gyrA9029c.1728T>G1.000
gyrA9032c.1731T>C1.000
gyrA9038c.1737C>A1.000
gyrA9050p.Asp583Glu1.000
gyrA9056c.1755C>G1.000
gyrA9065c.1764C>G1.000
gyrA9068c.1767G>C1.000
gyrA9071c.1770G>C0.312
gyrA9080c.1779G>T0.290
gyrA9251c.1950G>C1.000
gyrA9252p.Val651Ile1.000
gyrA9267p.Asn656Gly1.000
gyrA9275c.1974G>A0.800
gyrA9293c.1992G>C0.818
gyrA9296c.1995T>C1.000
gyrA9304p.Gly668Asp1.000
gyrA9323c.2022C>G1.000
gyrA9324c.2023T>A1.000
gyrA9335c.2034G>C1.000
gyrA9341c.2040C>G1.000
gyrA9345c.2044A>C1.000
gyrA9353c.2052G>C1.000
gyrA9356c.2055G>A1.000
gyrA9374c.2073G>T1.000
gyrA9377c.2076A>G1.000
gyrA9383c.2082T>C1.000
gyrA9386c.2085T>G1.000
gyrA9389c.2088C>G1.000
gyrA9407c.2106C>T1.000
gyrA9419c.2118T>C1.000
gyrA9420p.Ile707Glu1.000
gyrA9626c.2325T>C1.000
gyrA9630p.Val777Ile1.000
gyrA9635c.2334T>C1.000
gyrA9641c.2340C>T1.000
gyrA9644c.2343T>C1.000
gyrA9650c.2349G>C1.000
gyrA9656c.2355C>G1.000
gyrA9662c.2361G>C1.000
gyrA9668c.2367C>T1.000
gyrA9683c.2382G>T1.000
gyrA9689c.2388G>T1.000
gyrA9701c.2400T>C1.000
gyrA9707c.2406G>C1.000
gyrA9716c.2415T>C1.000
gyrA9738p.Leu813Ile1.000
gyrA9743c.2442C>G1.000
gyrA9746c.2445C>T1.000
rpoB759788c.-19A>G1.000
rpoB760046c.240G>C1.000
rpoB760059p.Tyr85Glu1.000
rpoB760067c.261G>C1.000
rpoB760070c.264T>C1.000
rpoB760082c.276C>T1.000
rpoB760088c.282C>G1.000
rpoB760091c.285G>C0.510
rpoB760101c.295T>C0.500
rpoB760104c.298T>A0.500
rpoB760112c.306T>C1.000
rpoB760118c.312T>G1.000
rpoB760121c.315T>C1.000
rpoB760130p.Asp108Glu1.000
rpoB760136c.330G>A1.000
rpoB760139c.333A>T1.000
rpoB760142c.336C>G1.000
rpoB760178c.372G>A0.964
rpoB760181c.375T>C1.000
rpoB760184c.378A>G1.000
rpoB760196c.390C>G1.000
rpoB760235c.429T>C1.000
rpoB760244c.438G>C1.000
rpoB760283c.477G>C1.000
rpoB760298c.492G>C1.000
rpoB760310c.504G>C1.000
rpoB760316c.510C>G1.000
rpoB760325c.519G>C1.000
rpoB760331c.525G>C1.000
rpoB760334c.528G>T1.000
rpoB760340c.534G>T1.000
rpoB760357p.Thr184Ser1.000
rpoB760361c.555T>C1.000
rpoB760376p.Asp190Glu1.000
rpoB760406c.600G>C0.952
rpoB760407p.Ser201Gly1.000
rpoB760415c.609C>T1.000
rpoB760424c.618C>G1.000
rpoB760430c.624T>C1.000
rpoB760457c.651C>T1.000
rpoB760463c.657C>T1.000
rpoB760475c.669A>G1.000
rpoB760478c.672C>T0.814
rpoB760481c.675G>T0.814
rpoB760484c.678A>G0.833
rpoB760502c.696C>G1.000
rpoB760522p.Ser239Asn1.000
rpoB760532c.726T>C1.000
rpoB760533p.Val243Thr1.000
rpoB760541c.735G>C1.000
rpoB760547c.741G>C1.000
rpoB760567p.Ser254Trp1.000
rpoB760571c.765G>C1.000
rpoB760585p.Asn260Ser1.000
rpoB760591p.Val262Ala1.000
rpoB760595c.789C>T1.000
rpoB760596p.Thr264Pro1.000
rpoB760611c.805T>C1.000
rpoB760646c.840C>G1.000
rpoB760655c.849A>G1.000
rpoB760661c.855A>C1.000
rpoB760670c.864G>C1.000
rpoB760674c.868T>C1.000
rpoB760679c.873A>G1.000
rpoB760683c.877T>C1.000
rpoB760721c.915C>G1.000
rpoB760724c.918T>C1.000
rpoB760730c.924T>C1.000
rpoB760748c.942C>G1.000
rpoB760751c.945G>C1.000
rpoB760755p.His317Asn1.000
rpoB760759p.Val318Ala1.000
rpoB760764p.Glu320Gln1.000
rpoB760769c.963C>G1.000
rpoB760784c.978G>T0.961
rpoB760793c.987A>G1.000
rpoB760805c.999G>C1.000
rpoB760817c.1011A>G1.000
rpoB760820c.1014T>C1.000
rpoB760826c.1020C>G1.000
rpoB760830c.1024T>C1.000
rpoB760841c.1035T>C1.000
rpoB760859c.1053T>C1.000
rpoB760862c.1056G>C1.000
rpoB760877c.1071G>C1.000
rpoB760883c.1077G>C1.000
rpoB760886c.1080A>G1.000
rpoB760887p.Thr361Val1.000
rpoB760910c.1104C>T1.000
rpoB760916c.1110C>T1.000
rpoB760919c.1113C>T1.000
rpoB760925c.1119T>C1.000
rpoB760928c.1122G>C1.000
rpoB760931c.1125C>G1.000
rpoB760946c.1140A>G1.000
rpoB760958c.1152G>C1.000
rpoB760965p.Met387Leu1.000
rpoB760970c.1164G>C1.000
rpoB760973c.1167G>C1.000
rpoB760982c.1176G>C1.000
rpoB760985c.1179G>C1.000
rpoB760988c.1182C>G1.000
rpoB760991c.1185G>T1.000
rpoB760997c.1191G>C1.000
rpoB761015c.1209G>C1.000
rpoB761027c.1221A>C1.000
rpoB761036c.1230G>C1.000
rpoB761037c.1231T>C1.000
rpoB761051c.1245G>T1.000
rpoB761054c.1248G>C1.000
rpoB761057c.1251G>C1.000
rpoB761060c.1254C>G1.000
rpoB761063c.1257C>G1.000
rpoB761084c.1278C>A1.000
rpoB761087c.1281C>G1.000
rpoB761088c.1282A>T1.000
rpoB761097c.1291A>T1.000
rpoB761102c.1296A>G1.000
rpoB761111c.1305C>T1.000
rpoB761132c.1326G>T1.000
rpoB761133c.1327T>C1.000
rpoB761147c.1341C>T1.000
rpoB761150c.1344A>T1.000
rpoB761165c.1359G>C1.000
rpoB761180c.1374A>C1.000
rpoB761189c.1383T>C1.000
rpoB761195c.1389G>C1.000
rpoB761198c.1392G>T1.000
rpoB761213c.1407G>C1.000
rpoB761217p.Pro471Ser0.978
rpoB761234c.1428G>C1.000
rpoB761249c.1443A>G1.000
rpoB761261c.1455G>T1.000
rpoB761264c.1458C>G1.000
rpoB761282c.1476C>T1.000
rpoB761288c.1482G>T1.000
rpoB761318c.1512G>T1.000
rpoB761327c.1521A>G1.000
rpoB761330c.1524G>C1.000
rpoB761345c.1539G>C1.000
rpoB761354c.1548C>T1.000
rpoB761360c.1554T>C1.000
rpoB761362p.Ser519Thr1.000
rpoB761367p.Glu521Gln1.000
rpoB761374p.Val523Asp1.000
rpoB761408c.1602G>C1.000
rpoB761414c.1608A>G1.000
rpoB761423c.1617T>C1.000
rpoB761435c.1629T>C1.000
rpoB761436p.Ala544Pro1.000
rpoB761444c.1638T>C1.000
rpoB761447c.1641C>G1.000
rpoB761451p.Val549Thr1.000
rpoB761457p.Pro551Asp1.000
rpoB761466p.Leu554Met1.000
rpoB761471c.1665C>T1.000
rpoB761474c.1668C>T1.000
rpoB761477c.1671C>T1.000
rpoB761482p.Ala559Gly1.000
rpoB761492c.1686G>C1.000
rpoB761496p.Tyr564Asn1.000
rpoB761502p.Pro566Ala1.000
rpoB761505p.Ser567Pro1.000
rpoB761510c.1704T>C1.000
rpoB761513p.Glu569Asp1.000
rpoB761516c.1710G>C1.000
rpoB761537c.1731C>G1.000
rpoB761552c.1746G>C1.000
rpoB761555c.1749G>C1.000
rpoB761558c.1752C>G1.000
rpoB761570c.1764T>C1.000
rpoB761573c.1767C>G1.000
rpoB761579c.1773G>C1.000
rpoB761600c.1794T>C0.512
rpoB761606c.1800C>G1.000
rpoB761612c.1806G>T1.000
rpoB761615c.1809A>C1.000
rpoB761636c.1830G>T1.000
rpoB761645c.1839C>G1.000
rpoB761648c.1842T>C1.000
rpoB761666c.1860G>C1.000
rpoB761669c.1863C>T1.000
rpoB761675c.1869G>T1.000
rpoB761690c.1884G>C1.000
rpoB761708c.1902C>T1.000
rpoB761712p.Val636Ile1.000
rpoB761717637VAEES>637VSEKA1.000
rpoB761733p.Val643Ile1.000
rpoB761736p.Ile644Val1.000
rpoB761747c.1941G>C1.000
rpoB761765c.1959T>C1.000
rpoB761772p.His656Ala1.000
rpoB761778p.Asn658Asp1.000
rpoB761785p.Thr660Ser1.000
rpoB761791p.Arg662His1.000
rpoB761813c.2007T>C1.000
rpoB761834c.2028T>C1.000
rpoB761847p.Cys681Arg1.000
rpoB761852c.2046C>G1.000
rpoB761864c.2058G>C0.882
rpoB761867c.2061C>G0.938
rpoB761868p.Asp688Gln1.000
rpoB761873c.2067A>T1.000
rpoB761885c.2079T>C0.467
rpoB761891c.2085G>C0.467
rpoB761892p.Ile696Val0.467
rpoB761906c.2100C>G1.000
rpoB761909c.2103T>C1.000
rpoB761912c.2106T>C1.000
rpoB761915p.Asp703Glu1.000
rpoB761916p.Asp704Asn1.000
rpoB761921c.2115C>T1.000
rpoB761930c.2124G>C1.000
rpoB761948c.2142G>C1.000
rpoB761954c.2148C>G1.000
rpoB762008c.2202C>T0.979
rpoB762014c.2208C>T1.000
rpoB762047c.2241G>A1.000
rpoB762053c.2247T>C0.949
rpoB762062c.2256T>C1.000
rpoB762065c.2259T>C1.000
rpoB762083c.2277T>C1.000
rpoB762086c.2280G>C1.000
rpoB762101c.2295C>G1.000
rpoB762114p.Ile770Val1.000
rpoB762131c.2325C>G0.549
rpoB762137c.2331C>T1.000
rpoB762140c.2334G>C1.000
rpoB762143c.2337T>C1.000
rpoB762149c.2343G>C1.000
rpoB762158c.2352G>C1.000
rpoB762167c.2361T>C1.000
rpoB762176c.2370T>C1.000
rpoB762185c.2379G>C1.000
rpoB762233c.2427G>C1.000
rpoB762245c.2439G>C1.000
rpoB762284c.2478G>T1.000
rpoB762287c.2481C>T1.000
rpoB762293c.2487T>C1.000
rpoB762308c.2502G>C1.000
rpoB762317c.2511A>G1.000
rpoB762329c.2523G>C1.000
rpoB762338c.2532T>C1.000
rpoB762341c.2535G>C1.000
rpoB762347c.2541T>C1.000
rpoB762350c.2544C>T0.968
rpoB762362p.Glu852Asp1.000
rpoB762369c.2563T>C1.000
rpoB762374c.2568G>C1.000
rpoB762395c.2589G>C1.000
rpoB762398c.2592T>C1.000
rpoB762401c.2595G>C1.000
rpoB762404c.2598T>C1.000
rpoB762410c.2604T>C1.000
rpoB762416c.2610A>G1.000
rpoB762434c.2628T>C1.000
rpoB762443c.2637G>C1.000
rpoB762449c.2643C>A1.000
rpoB762452c.2646G>C1.000
rpoB762470c.2664G>C1.000
rpoB762491c.2685T>C1.000
rpoB762509c.2703T>G1.000
rpoB762510p.Ala902Pro1.000
rpoB762515c.2709C>T1.000
rpoB762533c.2727T>C1.000
rpoB762536c.2730T>C1.000
rpoB762537c.2731T>C1.000
rpoB762551c.2745C>T1.000
rpoB762560c.2754A>T1.000
rpoB762563c.2757G>T1.000
rpoB762776c.2970C>T1.000
rpoB762782c.2976T>C1.000
rpoB762788c.2982G>C1.000
rpoB762789p.Leu995Met1.000
rpoB762794c.2988C>G1.000
rpoB762795p.Asp997Asn1.000
rpoB762812c.3006C>G1.000
rpoB762814p.Met1003Thr1.000
rpoB762816c.3010C>T1.000
rpoB762827c.3021G>C1.000
rpoB762833c.3027C>T1.000
rpoB762839c.3033G>A1.000
rpoB762857c.3051C>G1.000
rpoB762863c.3057T>C1.000
rpoB762879p.Met1025Leu1.000
rpoB762920c.3114C>T1.000
rpoB762929c.3123G>C1.000
rpoB762959c.3153G>C1.000
rpoB762962c.3156C>T0.982
rpoB762995c.3189G>T0.965
rpoB763004c.3198G>A1.000
rpoB763007c.3201C>T1.000
rpoB763028c.3222T>C1.000
rpoB763031c.3225T>G1.000
rpoB763053c.3247T>C1.000
rpoB763070c.3264T>C1.000
rpoB763085c.3279C>G1.000
rpoB763103c.3297G>C1.000
rpoB763115c.3309T>C1.000
rpoB763127c.3321G>C1.000
rpoB763130c.3324G>A1.000
rpoB763133c.3327G>C1.000
rpoB763136c.3330C>T1.000
rpoB763142c.3336C>G1.000
rpoB763160c.3354G>T1.000
rpoB763166c.3360A>G1.000
rpoB763169c.3363A>G1.000
rpoB763190c.3384C>T1.000
rpoB763199c.3393G>C1.000
rpoB763202c.3396A>G1.000
rpoB763205c.3399G>T1.000
rpoB763206c.3400A>T1.000
rpoB763217c.3411G>C1.000
rpoB763226c.3420A>G1.000
rpoB763227p.Leu1141Met1.000
rpoB763232c.3426C>T1.000
rpoB763235p.Glu1143Asp1.000
rpoB763241p.Glu1145Asp1.000
rpoB763259c.3453G>C1.000
rpoB763262c.3456C>T1.000
rpoB763265c.3459G>C1.000
rpoB763268c.3462C>G1.000
rpoB763283c.3477T>C1.000
rpoB763289c.3483C>G1.000
rpoB763298c.3492A>G1.000
rpoC763375c.6C>A1.000
rpoC763408c.39T>C1.000
rpoC763411c.42T>C1.000
rpoC763414c.45T>C1.000
rpoC763423p.Glu18Asp1.000
rpoC763430c.61A>C1.000
rpoC763433p.Gln22Asn1.000
rpoC763443p.Tyr25Phe1.000
rpoC763456c.87A>G1.000
rpoC763468c.99G>C1.000
rpoC763486c.117T>C1.000
rpoC763492c.123G>T1.000
rpoC763528c.159G>A1.000
rpoC763546c.177A>G1.000
rpoC763558c.189C>T1.000
rpoC763570c.201G>C1.000
rpoC763573c.204G>C1.000
rpoC763588c.219C>T1.000
rpoC763594c.225C>T1.000
rpoC763603c.234C>T1.000
rpoC763615c.246G>C1.000
rpoC763618c.249C>T1.000
rpoC763633c.264T>C0.806
rpoC763660c.291T>G1.000
rpoC763666c.297G>A1.000
rpoC763675c.306C>G1.000
rpoC763702c.333C>G1.000
rpoC763709c.340C>T1.000
rpoC763714c.345G>C1.000
rpoC763717c.348T>C1.000
rpoC763723c.354G>C1.000
rpoC763732c.363C>T1.000
rpoC763741c.372C>T1.000
rpoC763747c.378G>A1.000
rpoC763765c.396T>G1.000
rpoC763792p.Glu141Asp1.000
rpoC763807c.438T>C1.000
rpoC763813c.444C>G1.000
rpoC763831c.462A>G1.000
rpoC763837c.468G>C1.000
rpoC763840c.471G>C1.000
rpoC763858c.489A>G1.000
rpoC763861c.492C>T1.000
rpoC763872p.Gly168Ala1.000
rpoC763876p.Glu169Asp1.000
rpoC763879c.510A>G1.000
rpoC763882c.513G>A1.000
rpoC763891c.522G>C1.000
rpoC763894c.525A>G1.000
rpoC763900c.531G>C1.000
rpoC763921c.552G>C1.000
rpoC763924c.555G>A0.976
rpoC763930c.561G>A1.000
rpoC763933c.564C>T1.000
rpoC763940p.Ala191Ser1.000
rpoC763945c.576T>C1.000
rpoC763947p.Ala193Val1.000
rpoC763951c.582G>C1.000
rpoC763960c.591T>G1.000
rpoC763969c.600C>T1.000
rpoC763978c.609C>T1.000
rpoC763987c.618C>T1.000
rpoC763991p.Ile208Leu1.000
rpoC763996c.627T>C1.000
rpoC764005c.636G>C1.000
rpoC764024c.655T>C1.000
rpoC764029p.Glu220Asp1.000
rpoC764032p.Asp221Glu1.000
rpoC764040p.Ser224Thr1.000
rpoC764044c.675T>C1.000
rpoC764059c.690G>T1.000
rpoC764071c.702G>C1.000
rpoC764083c.714A>G1.000
rpoC764084p.Asn239Val1.000
rpoC764089c.720C>G1.000
rpoC764098c.729A>G0.564
rpoC764101c.732C>G0.564
rpoC764102p.Val245Gln0.564
rpoC764153p.Gln262Lys1.000
rpoC764161c.792G>C1.000
rpoC764182p.Asp271Glu1.000
rpoC764188c.819A>G1.000
rpoC764195c.826T>A1.000
rpoC764203c.834G>C1.000
rpoC764206p.Asp279Glu1.000
rpoC764207p.Val280Thr1.000
rpoC764215c.846A>C1.000
rpoC764217p.Asn283Ser1.000
rpoC764239c.870T>G1.000
rpoC764254c.885G>C1.000
rpoC764257c.888G>C1.000
rpoC764263c.894G>C1.000
rpoC764266c.897T>C1.000
rpoC764272c.903G>C1.000
rpoC764278c.909A>G1.000
rpoC764293c.924G>C1.000
rpoC764297p.Met310Leu1.000
rpoC764344c.975C>T1.000
rpoC764353c.984G>T1.000
rpoC764365c.996C>T1.000
rpoC764371c.1002G>C1.000
rpoC764380c.1011G>C1.000
rpoC764387c.1018T>C1.000
rpoC764405c.1036A>C0.537
rpoC764431c.1062G>C1.000
rpoC764434c.1065A>G1.000
rpoC764435c.1066A>C1.000
rpoC764446c.1077T>C1.000
rpoC764449c.1080G>C1.000
rpoC764458c.1089G>C1.000
rpoC764461c.1092A>G1.000
rpoC764485c.1116G>C1.000
rpoC764491c.1122G>T1.000
rpoC764497c.1128A>G1.000
rpoC764500c.1131C>G1.000
rpoC764512c.1143G>T1.000
rpoC764521c.1152T>C1.000
rpoC764527c.1158C>T1.000
rpoC764536c.1167G>T1.000
rpoC764539c.1170C>G1.000
rpoC764575c.1206T>G1.000
rpoC764605c.1236G>C1.000
rpoC764611c.1242G>T1.000
rpoC764623c.1254C>G1.000
rpoC764626c.1257C>T1.000
rpoC764632c.1263T>C1.000
rpoC764650c.1281G>T1.000
rpoC764701c.1332C>G1.000
rpoC764713c.1344G>T1.000
rpoC764716c.1347G>C1.000
rpoC764746c.1377G>T1.000
rpoC764752c.1383G>C1.000
rpoC764758c.1389C>G1.000
rpoC764764c.1395T>C1.000
rpoC764803c.1434C>T1.000
rpoC764809c.1440C>T0.979
rpoC764815c.1446A>G1.000
rpoC764824c.1455T>C1.000
rpoC764827c.1458G>C1.000
rpoC764858c.1489T>C1.000
rpoC764869c.1500C>T1.000
rpoC764875c.1506C>T1.000
rpoC764878c.1509C>G1.000
rpoC764887c.1518G>C1.000
rpoC764888c.1519T>C1.000
rpoC764911c.1542A>G1.000
rpoC764912p.Met515Gln1.000
rpoC764935c.1566T>C1.000
rpoC764948c.1579T>C1.000
rpoC764968c.1599T>C1.000
rpoC765007c.1638T>G1.000
rpoC765008c.1639T>C1.000
rpoC765011c.1642A>T1.000
rpoC765016c.1647C>A1.000
rpoC765019c.1650A>G1.000
rpoC765034c.1665T>C1.000
rpoC765040c.1671T>C1.000
rpoC765041c.1672T>C1.000
rpoC765047c.1678T>C1.000
rpoC765055c.1686C>G1.000
rpoC765073c.1704G>C1.000
rpoC765076c.1707A>G1.000
rpoC765089c.1720T>C1.000
rpoC765103c.1734G>T1.000
rpoC765121c.1752G>T1.000
rpoC765129p.Tyr587Phe1.000
rpoC765259c.1890G>C1.000
rpoC765284p.Gln639Asp1.000
rpoC765287p.Leu640Ala1.000
rpoC765292c.1923G>T1.000
rpoC765300p.Val644Ala1.000
rpoC765302p.Glu645Asn1.000
rpoC765319c.1950A>G1.000
rpoC765328p.His653Gln1.000
rpoC765330p.Ser654Asn1.000
rpoC765338p.Gln657Lys1.000
rpoC765352c.1983G>C1.000
rpoC765357p.Met663Thr1.000
rpoC765361c.1992C>G1.000
rpoC765383p.Met672Leu1.000
rpoC765403c.2034G>C1.000
rpoC765404p.Leu679Lys1.000
rpoC765409c.2040T>C1.000
rpoC765412c.2043T>C1.000
rpoC765425p.Lys686Glu1.000
rpoC765445c.2076G>C1.000
rpoC765452p.Ala695Arg1.000
rpoC765466c.2097C>T1.000
rpoC765478c.2109T>C1.000
rpoC765480p.Tyr704Phe1.000
rpoC765496c.2127C>G1.000
rpoC765499c.2130C>G1.000
rpoC765529c.2160C>T1.000
rpoC765533p.Tyr722His1.000
rpoC765547c.2178C>T1.000
rpoC765548c.2179A>T1.000
rpoC765553c.2184C>T1.000
rpoC765556c.2187G>C1.000
rpoC765562c.2193G>T1.000
rpoC765577c.2208G>T1.000
rpoC765591p.Arg741Gln1.000
rpoC765596p.Lys743Gln1.000
rpoC765772c.2403C>G1.000
rpoC765778c.2409C>G1.000
rpoC765779p.Asp804Lys1.000
rpoC765793c.2424C>G1.000
rpoC765796c.2427C>T1.000
rpoC765800p.Phe811Leu1.000
rpoC765811c.2442T>G1.000
rpoC765814c.2445A>C1.000
rpoC765817c.2448G>C1.000
rpoC765823c.2454C>A1.000
rpoC765826c.2457T>C1.000
rpoC765835c.2466C>T1.000
rpoC765871c.2502T>C1.000
rpoC765875p.Val836Ile1.000
rpoC765886c.2517C>G1.000
rpoC765904c.2535C>G1.000
rpoC765908c.2539C>T1.000
rpoC765934c.2565C>T1.000
rpoC765940c.2571A>T1.000
rpoC765946c.2577C>T1.000
rpoC765947c.2578T>C1.000
rpoC765952c.2583G>C1.000
rpoC765961c.2592G>T1.000
rpoC765962c.2593T>C1.000
rpoC765967c.2598C>T1.000
rpoC765979c.2610C>G0.806
rpoC765982c.2613C>T0.803
rpoC765994c.2625A>T1.000
rpoC766012c.2643C>G1.000
rpoC766021c.2652G>C1.000
rpoC766027c.2658G>T1.000
rpoC766034p.His889Thr1.000
rpoC766042c.2673C>T1.000
rpoC766043p.Gln892Glu1.000
rpoC766061p.Val898Ile1.000
rpoC766067p.Glu900Thr1.000
rpoC766309c.2940G>C1.000
rpoC766315c.2946C>G1.000
rpoC766345c.2976T>C1.000
rpoC766348c.2979A>G1.000
rpoC766363c.2994G>C1.000
rpoC766381c.3012C>T1.000
rpoC766384c.3015A>G1.000
rpoC766390c.3021C>T1.000
rpoC766408c.3039C>T1.000
rpoC766456c.3087C>T1.000
rpoC766459c.3090G>T0.976
rpoC766462c.3093G>C1.000
rpoC766483c.3114G>T1.000
rpoC766484p.Val1039Ile1.000
rpoC766492c.3123T>G1.000
rpoC766493p.Gly1042Asn1.000
rpoC766504c.3135G>C1.000
rpoC766513c.3144C>T1.000
rpoC766517p.Thr1050Ala1.000
rpoC766528c.3159T>C1.000
rpoC766534c.3165C>G1.000
rpoC766554p.Tyr1062Phe1.000
rpoC766573c.3204T>C1.000
rpoC766579c.3210C>T1.000
rpoC766585c.3216T>C1.000
rpoC766594c.3225G>T1.000
rpoC766607p.Ile1080Leu1.000
rpoC766618c.3249G>T1.000
rpoC766624c.3255G>C1.000
rpoC766630c.3261G>C1.000
rpoC766634p.Phe1089Ile1.000
rpoC766638p.Lys1090Thr1.000
rpoC766645c.3276A>G1.000
rpoC766651c.3282T>C1.000
rpoC766658p.Arg1097Gly1.000
rpoC766666c.3297C>G1.000
rpoC766672c.3303T>C1.000
rpoC766675c.3306C>T1.000
rpoC766690c.3321G>C1.000
rpoC766694p.Gln1109Asp1.000
rpoC766714c.3345G>C1.000
rpoC766717c.3348C>G1.000
rpoC766720c.3351C>T1.000
rpoC766726c.3357T>C1.000
rpoC766738c.3369G>T1.000
rpoC766741c.3372G>C1.000
rpoC766765c.3396A>C1.000
rpoC766771c.3402G>C1.000
rpoC766774c.3405T>C1.000
rpoC766775p.Arg1136Lys1.000
rpoC766798c.3429C>G1.000
rpoC766804c.3435A>G1.000
rpoC766807c.3438T>C1.000
rpoC766837c.3468G>C1.000
rpoC766843c.3474T>C1.000
rpoC766846c.3477C>G1.000
rpoC766858c.3489C>T1.000
rpoC766861c.3492G>C1.000
rpoC766864c.3495G>C1.000
rpoC766867c.3498C>G1.000
rpoC766876c.3507C>T1.000
rpoC766931p.Ala1188Thr1.000
rpoC766942c.3573C>T1.000
rpoC766945c.3576A>C1.000
rpoC766948c.3579G>C1.000
rpoC766963c.3594T>C1.000
rpoC766981c.3612T>C1.000
rpoC766996c.3627C>T1.000
rpoC767002c.3633G>C1.000
rpoC767008c.3639G>A1.000
rpoC767020c.3651C>G0.793
rpoC767098c.3729T>C1.000
rpoC767104c.3735C>G1.000
rpoC767105p.Asn1246Gln1.000
rpoC767119c.3750A>G1.000
rpoC767134c.3765C>T1.000
rpoC767138c.3769C>T1.000
rpoC767158c.3789T>C1.000
rpoC767162p.Asn1265Ala1.000
rpoC767167c.3798C>T1.000
rpoC767174p.Asn1269Asp0.960
rpoC767180p.Ala1271Gln1.000
rpoC767191c.3822C>G1.000
rpoC767197c.3828G>A1.000
rpoC767221c.3852C>G1.000
rpoC767230c.3861G>C1.000
rpoC767233c.3864T>C1.000
rpoC767263c.3894T>C1.000
rpoC767264p.Ala1299Gln1.000
rpoC767278c.3909T>C1.000
rpoC767281c.3912C>G1.000
rpoC767284c.3915C>G1.000
rpoC767296c.3927C>T1.000
rpoC767302c.3933C>A1.000
rpsL781559c.-1G>C1.000
rpsL781572p.Gln5Asn1.000
rpsL781595c.36T>C1.000
rpsL781598c.39G>C1.000
rpsL781605p.Ile16Val1.000
rpsL781608p.Ser17Ala1.000
rpsL781628c.69T>C1.000
rpsL781631c.72G>C1.000
rpsL781649c.90T>C1.000
rpsL781655c.96T>C1.000
rpsL781658c.99A>G1.000
rpsL781682c.123T>C1.000
rpsL781709c.150G>C1.000
rpsL781715c.156T>C1.000
rpsL781728c.169T>C1.000
rpsL781742c.183C>T1.000
rpsL781751c.192G>C1.000
rpsL781760c.201T>C1.000
rpsL781772c.213C>T1.000
rpsL781808c.249C>T1.000
rpsL781814c.255C>T1.000
rpsL781817c.258G>T1.000
rpsL781829c.270G>C1.000
rpsL781832c.273T>C1.000
rpsL781838c.279G>C1.000
rpsL781841c.282C>T1.000
rpsL781859c.300T>G1.000
rpsL781865c.306G>C1.000
rpsL781868c.309T>C1.000
rpsL781871c.312G>C0.980
rpsL781892c.333A>G1.000
rpsL781898c.339A>C1.000
rpsL781901c.342C>T1.000
rpsL781907c.348T>C1.000
rpsL781916c.357T>C1.000
rpsL781929p.Gly124Ser0.981
rplC800844c.36T>C1.000
rplC800856c.48A>G1.000
rplC800862c.54C>T1.000
rplC800865c.57A>G1.000
rplC800867p.Ser20Asn1.000
rplC800873p.Arg22Lys1.000
rplC800877c.69A>C1.000
rplC800880c.72A>C1.000
rplC800889c.81C>G1.000
rplC800892c.84G>C1.000
rplC800895c.87C>G1.000
rplC800904c.96G>C1.000
rplC800916c.108A>G1.000
rplC800921p.Arg38Leu1.000
rplC800928c.120C>T1.000
rplC800931c.123G>C1.000
rplC800937c.129A>G1.000
rplC800946c.138T>C1.000
rplC800949c.141T>C1.000
rplC800964c.156G>C1.000
rplC800985c.177A>G1.000
rplC801171c.363A>G1.000
rplC801174c.366T>C1.000
rplC801195c.387G>T1.000
rplC801205p.Arg133Ala1.000
rplC801210c.402T>C1.000
rplC801220p.Ser138Ala1.000
rplC801231c.423C>T1.000
rplC801237c.429G>A1.000
rplC801252c.444G>C1.000
rplC801264c.456C>T1.000
rplC801267c.459A>C1.000
rplC801276c.468G>C1.000
rplC801281p.Ala158Gly0.970
rplC801285c.477G>C1.000
rplC801307p.Ala167Ser1.000
rplC801312c.504G>C1.000
rplC801315c.507G>T1.000
rplC801324c.516T>C1.000
rplC801337p.Val177Thr1.000
rplC801341p.Leu178Gln1.000
rplC801348c.540T>G1.000
rplC801349p.Leu181Lys1.000
rplC801354c.546G>T1.000
rplC801357c.549T>C1.000
rplC801385c.577C>T0.750
embR1416351p.Val333Ile0.818
embR1416355c.993G>C0.818
embR1416685c.663T>C1.000
embR1416691p.Asp219Glu1.000
embR1416696p.Ser218Ala1.000
embR1416697c.651G>A1.000
rrs1471922r.77gt>g1.000
rrs1471925r.80t>c1.000
rrs1471931r.86ga>g1.000
rrs1471934r.89a>g1.000
rrs1471986r.141c>t1.000
rrs1472019r.174g>a1.000
rrs1472023r.178g>t1.000
rrs1472031r.186g>c1.000
rrs1472033r.188a>c1.000
rrs1472035r.190g>t1.000
rrs1472040r.195t>g1.000
rrs1472041r.196c>t0.986
rrs1472042r.197t>g1.000
rrs1472053r.208agc>a1.000
rrs1472061r.216a>t1.000
rrs1472075r.230a>g1.000
rrs1472106r.261g>a1.000
rrs1472108r.263c>t1.000
rrs1472150r.305t>a1.000
rrs1472251r.406g>a1.000
rrs1472286r.441c>a1.000
rrs1472287r.442c>t1.000
rrs1472289r.444t>g1.000
rrs1472290r.445c>g1.000
rrs1472297r.452ggtccgggttctct>g1.000
rrs1472312r.467g>gc1.000
rrs1472313r.468g>a1.000
rrs1472315r.470t>g1.000
rrs1472324r.479g>c1.000
rrs1472325r.480g>c1.000
rrs1472327r.482g>a1.000
rrs1472328r.483g>t1.000
rrs1472337r.492c>g1.000
rrs1472380r.535g>c1.000
rrs1472446r.601t>a1.000
rrs1472452r.607g>a1.000
rrs1472464r.619a>g0.982
rrs1472846r.1001c>a1.000
rrs1472847r.1002g>c1.000
rrs1472849r.1004c>g1.000
rrs1472850r.1005t>c1.000
rrs1472857r.1012a>g1.000
rrs1472858r.1013g>t1.000
rrs1472860r.1015c>g0.971
rrs1472861r.1016g>t0.971
rrs1472973r.1128a>t1.000
rrs1473104r.1259c>t1.000
rrs1473110r.1265t>g1.000
rrs1473111r.1266a>g1.000
rrs1473120r.1275c>ct0.947
rrs1473123r.1278a>c1.000
rrs1473276r.1431a>g1.000
rrs1473290r.1445c>t1.000
rrs1473291r.1446g>gt1.000
rrs1473301r.1456t>c1.000
rrl1473568c.-90G>T1.000
rrl1473569c.-89A>T1.000
rrl1473570c.-88A>T1.000
rrl1473571c.-87C>G1.000
rrl1473668r.11c>t1.000
rrl1473696r.39t>c1.000
rrl1473697r.40c>t1.000
rrl1473699r.42a>g1.000
rrl1473717r.60g>t1.000
rrl1473746r.89t>c1.000
rrl1473758r.101g>t1.000
rrl1473770r.113t>g1.000
rrl1473788r.131a>g1.000
rrl1473806r.149c>t1.000
rrl1473807r.150t>c1.000
rrl1473823r.166t>c1.000
rrl1473829r.172g>t1.000
rrl1473830r.173t>g1.000
rrl1473831r.174g>t1.000
rrl1473832r.175c>a1.000
rrl1473876r.219g>a1.000
rrl1473887r.230t>a1.000
rrl1473898r.241c>t1.000
rrl1473899r.242a>g1.000
rrl1473916r.259c>a1.000
rrl1473922r.265a>g1.000
rrl1473923r.266c>g1.000
rrl1473935r.278c>t1.000
rrl1473937r.280c>t1.000
rrl1473943r.286g>t1.000
rrl1473945r.288t>a1.000
rrl1473946r.289a>t1.000
rrl1473981r.324g>c0.333
rrl1473984r.327t>c1.000
rrl1473985r.328a>c1.000
rrl1473989r.332c>t1.000
rrl1473994r.337c>t1.000
rrl1473995r.338g>t1.000
rrl1474001r.344c>t1.000
rrl1474007r.350a>g1.000
rrl1474008r.351g>a1.000
rrl1474009r.352a>g1.000
rrl1474012r.355c>t1.000
rrl1474016r.359c>g1.000
rrl1474022r.365g>a1.000
rrl1474044r.387c>t1.000
rrl1474045r.388c>t1.000
rrl1474053r.396g>a1.000
rrl1474054r.397t>c1.000
rrl1474083r.426c>t1.000
rrl1474091r.434c>t1.000
rrl1474093r.436g>a1.000
rrl1474096r.439c>t1.000
rrl1474099r.442g>a1.000
rrl1474108r.451c>g1.000
rrl1474110r.453a>acggtg1.000
rrl1474135r.478g>a1.000
rrl1474140r.483c>t1.000
rrl1474151r.494c>t1.000
rrl1474174r.517a>g1.000
rrl1474181r.524c>t1.000
rrl1474183r.526t>c1.000
rrl1474185r.528g>a1.000
rrl1474186r.529a>g1.000
rrl1474249r.592g>t1.000
rrl1474266r.609t>c0.986
rrl1474269r.612c>t1.000
rrl1474289r.632c>t1.000
rrl1474292r.635t>g1.000
rrl1474294r.637cctctccggagga>c1.000
rrl1474308r.651g>t1.000
rrl1474310r.653t>g1.000
rrl1474362r.705a>g1.000
rrl1474414r.757c>t1.000
rrl1474415r.758ccacacg>c1.000
rrl1474421r.764gcgc>g1.000
rrl1474426r.769t>c0.976
rrl1474427r.770acgc>a1.000
rrl1474428r.771c>g1.000
rrl1474429r.772g>t1.000
rrl1474430r.773c>a1.000
rrl1474432r.775c>t1.000
rrl1474436r.779t>tg1.000
rrl1474438r.781a>t1.000
rrl1474439r.782a>g1.000
rrl1474446r.789c>t1.000
rrl1474626r.969t>c1.000
rrl1474627r.970g>a1.000
rrl1474629r.972g>a1.000
rrl1474632r.975g>t1.000
rrl1474636r.979a>t1.000
rrl1474637r.980c>t1.000
rrl1474638r.981c>g1.000
rrl1474639r.982g>t1.000
rrl1474640r.983c>t1.000
rrl1474673r.1016t>c1.000
rrl1474676r.1019t>a1.000
rrl1474677r.1020a>g1.000
rrl1474710r.1053t>a1.000
rrl1474711r.1054g>c1.000
rrl1474712r.1055g>a1.000
rrl1474713r.1056t>a1.000
rrl1474717r.1060a>g0.989
rrl1474720r.1063c>t0.989
rrl1474753r.1096a>g1.000
rrl1474760r.1103a>g0.993
rrl1474794r.1137c>t0.993
rrl1474803r.1146g>a1.000
rrl1474812r.1155g>a1.000
rrl1474830r.1173a>g1.000
rrl1474932r.1275c>t1.000
rrl1474952r.1295acatcc>a1.000
rrl1474960r.1303c>t1.000
rrl1474963r.1306g>a1.000
rrl1474965r.1308g>c1.000
rrl1474990r.1333c>t1.000
rrl1474991r.1334t>g1.000
rrl1474995r.1338t>c1.000
rrl1474997r.1340a>g1.000
rrl1474999r.1342c>t1.000
rrl1475005r.1348c>a1.000
rrl1475006r.1349a>g1.000
rrl1475008r.1351c>a1.000
rrl1475010r.1353g>a1.000
rrl1475015r.1358c>t1.000
rrl1475018r.1361g>c1.000
rrl1475031r.1374g>t1.000
rrl1475061r.1404c>a1.000
rrl1475062r.1405a>t1.000
rrl1475120r.1463g>t1.000
rrl1475315r.1658a>t1.000
rrl1475353r.1696a>t1.000
rrl1475354r.1697a>g1.000
rrl1475355r.1698c>t1.000
rrl1475363r.1706c>t1.000
rrl1475369r.1712g>t1.000
rrl1475379r.1722g>a1.000
rrl1475380r.1723c>a1.000
rrl1475381r.1724g>c1.000
rrl1475382r.1725a>g1.000
rrl1475395r.1738t>c1.000
rrl1475396r.1739c>g1.000
rrl1475397r.1740g>t1.000
rrl1475398r.1741c>t1.000
rrl1475403r.1746t>a1.000
rrl1475404r.1747a>t1.000
rrl1475419r.1762c>t1.000
rrl1475429r.1772g>t1.000
rrl1475452r.1795c>a1.000
rrl1475479r.1822c>g1.000
rrl1475483r.1826c>t1.000
rrl1475505r.1848g>a1.000
rrl1475526r.1869c>a1.000
rrl1475531r.1874c>t1.000
rrl1475544r.1887a>t1.000
rrl1475545r.1888t>g1.000
rrl1475602r.1945g>c1.000
rrl1475603r.1946g>c1.000
rrl1475604r.1947a>c1.000
rrl1475612r.1955g>c1.000
rrl1475615r.1958c>g1.000
rrl1475616r.1959a>g1.000
rrl1475618r.1961c>t1.000
rrl1475625r.1968g>gc1.000
rrl1475626r.1969t>c1.000
rrl1475629r.1972g>c1.000
rrl1475637r.1980t>g1.000
rrl1475638r.1981c>g1.000
rrl1475639r.1982c>g1.000
rrl1475643r.1986c>g1.000
rrl1475647r.1990g>c1.000
rrl1475659r.2002g>a1.000
rrl1475753r.2096c>t1.000
rrl1475762r.2105g>t0.990
rrl1475763r.2106c>t1.000
rrl1475764r.2107a>c1.000
rrl1475765r.2108a>g1.000
rrl1475775r.2118g>a1.000
rrl1475988r.2331a>g1.000
rrl1475991r.2334t>c1.000
rrl1475995r.2338g>a1.000
rrl1476030r.2373a>g1.000
rrl1476032r.2375c>a1.000
rrl1476033r.2376t>g1.000
rrl1476035r.2378g>c1.000
rrl1476044r.2387t>g1.000
rrl1476046r.2389g>t0.986
rrl1476047r.2390g>t1.000
rrl1476049r.2392c>t1.000
rrl1476088r.2431a>c0.990
rrl1476099r.2442a>g1.000
rrl1476103r.2446c>g1.000
rrl1476105r.2448g>a1.000
rrl1476106r.2449a>t1.000
rrl1476110r.2453g>c1.000
rrl1476115r.2458t>c1.000
rrl1476131r.2474c>t0.984
rrl1476160r.2503t>c1.000
rrl1476214r.2557g>t1.000
rrl1476215r.2558c>t1.000
rrl1476224r.2567a>g1.000
rrl1476251r.2594t>g1.000
rrl1476256r.2599a>t1.000
rrl1476260r.2603a>g0.980
rrl1476281r.2624t>c1.000
rrl1476297r.2640c>t1.000
rrl1476299r.2642c>t1.000
rrl1476529r.2872a>g1.000
rrl1476540r.2883c>t1.000
rrl1476583r.2926g>a1.000
rrl1476584r.2927c>t1.000
rrl1476594r.2937c>t1.000
rrl1476597r.2940g>a1.000
rrl1476603r.2946g>a0.992
rrl1476628r.2971t>a1.000
rrl1476664r.3007t>c1.000
rrl1476665r.3008t>c1.000
rrl1476674r.3017t>c1.000
rrl1476679r.3022t>c1.000
rrl1476689r.3032a>t1.000
rrl1476690r.3033c>t1.000
rrl1476693r.3036g>a1.000
rrl1476695r.3038t>a1.000
rrl1476716r.3059a>c1.000
rrl1476723r.3066t>a1.000
rrl1476725r.3068c>t1.000
rrl1476726r.3069a>g1.000
rrl1476731r.3074g>a1.000
rrl1476732r.3075t>c1.000
rrl1476746r.3089t>c1.000
rrl1476747r.3090c>t1.000
rrl1476754r.3097g>a1.000
rrl1476759r.3102t>c1.000
rrl1476770r.3113t>c0.980
rrl1476771r.3114g>a1.000
fabG11673535c.96A>G0.467
fabG11673541c.102G>A0.429
fabG11673682c.243G>C1.000
fabG11673703c.264C>T1.000
fabG11673724c.285A>G1.000
fabG11673730c.291C>G1.000
fabG11673745c.306G>A1.000
fabG11673748c.309A>G1.000
fabG11673749p.Lys104Arg1.000
fabG11673760p.Lys107Asn1.000
fabG11673772c.333C>A1.000
fabG11673778c.339C>G1.000
fabG11673784c.345G>T0.978
fabG11673787c.348G>C1.000
fabG11673799c.360T>C1.000
fabG11673802c.363A>G1.000
fabG11673808c.369A>C1.000
fabG11673829p.Asn130Lys1.000
fabG11673830p.Lys131Arg1.000
fabG11673838c.399T>C1.000
fabG11673841c.402A>G1.000
fabG11673844p.Met135Ile1.000
fabG11673847c.408A>C1.000
fabG11673853c.414A>C1.000
fabG11673856c.417T>C1.000
fabG11673859c.420G>C1.000
fabG11673865c.426C>G1.000
fabG11673870p.Ser144Met1.000
fabG11673877c.438C>G1.000
fabG11673905p.Ser156Ala1.000
fabG11673916c.477A>C1.000
fabG11673917p.Val160Leu1.000
fabG11673922c.483T>C1.000
fabG11673931c.492C>G0.974
fabG11673941p.Ala168Ser0.585
fabG11673952c.513G>C0.463
fabG11673955c.516G>C0.463
fabG11673961c.522A>C1.000
fabG11673962p.Asn175Gly1.000
fabG11673967c.528G>C1.000
fabG11673973c.534G>C1.000
fabG11673976c.537T>C1.000
fabG11674006p.Asp189Glu1.000
fabG11674024c.585T>C1.000
fabG11674147c.708C>G0.167
fabG11674153c.714G>C0.167
inhA1674331p.Leu44Met0.969
inhA1674334p.Arg45Lys1.000
inhA1674342c.141T>C1.000
inhA1674352p.Thr51Ala1.000
inhA1674361c.160C>T1.000
inhA1674375c.174C>G1.000
inhA1674384c.183C>G1.000
inhA1674399c.198A>G1.000
inhA1674651c.450C>T1.000
inhA1674656p.Ser152Thr1.000
inhA1674660c.459G>C1.000
inhA1674663c.462G>C1.000
inhA1674672c.471C>A1.000
inhA1674690c.489C>G1.000
inhA1674702c.501G>T1.000
inhA1674703c.502T>C1.000
inhA1674718c.517A>C1.000
inhA1674729c.528G>T0.556
inhA1674742p.Lys181Ala1.000
inhA1674745p.Tyr182Ala1.000
inhA1674753c.552G>C1.000
inhA1674768c.567T>C1.000
inhA1674774c.573A>C1.000
inhA1674780c.579T>G1.000
inhA1674789c.588G>T1.000
inhA1674792c.591G>C1.000
inhA1674795c.594G>C1.000
inhA1674801c.600T>C1.000
inhA1674804c.603G>C1.000
inhA1674816c.615T>C1.000
inhA1674819c.618G>A1.000
inhA1674822c.621C>G1.000
inhA1674825c.624C>T1.000
inhA1674828p.Glu209Asp1.000
inhA1674834c.633C>G1.000
inhA1674838p.Ala213Lys0.952
inhA1674846p.Ile215Met1.000
inhA1674855c.654C>G1.000
inhA1674858c.657G>A1.000
inhA1674876c.675C>T1.000
inhA1674879c.678T>G1.000
inhA1674904p.Ala235Pro1.000
inhA1674924c.723G>C1.000
inhA1674930c.729C>T1.000
inhA1674934c.733C>T1.000
inhA1674942c.741T>C1.000
inhA1674949p.Leu250Met1.000
inhA1674954c.753G>C1.000
inhA1674957c.756G>C1.000
inhA1674963c.762G>A1.000
inhA1674966c.765T>C1.000
inhA1674967p.Asp256Thr1.000
rpsA1833539c.-3A>C1.000
rpsA1833541c.-1T>C1.000
rpsA1833547c.6G>A1.000
rpsA1833554p.Thr5Ser1.000
rpsA1833589c.48A>C1.000
rpsA1833595c.54T>G1.000
rpsA1833596p.Ser19Ala1.000
rpsA1833616c.75A>C1.000
rpsA1833619c.78A>C1.000
rpsA1833628c.87G>C1.000
rpsA1833634c.93G>A1.000
rpsA1833661c.120A>G1.000
rpsA1833664c.123C>A1.000
rpsA1833676c.135A>G1.000
rpsA1833679c.138G>T1.000
rpsA1833685c.144G>T1.000
rpsA1833694c.153G>C1.000
rpsA1833697c.156C>G1.000
rpsA1833703c.162C>T1.000
rpsA1833709c.168C>T1.000
rpsA1833724c.183C>T0.976
rpsA1833727c.186G>C1.000
rpsA1833730c.189C>T1.000
rpsA1833733c.192C>T0.951
rpsA1833734p.Ala65Ser1.000
rpsA1833745c.204G>C1.000
rpsA1833760c.219C>T1.000
rpsA1833787c.246C>G1.000
rpsA1833790c.249T>C1.000
rpsA1833793c.252C>T1.000
rpsA1833802c.261A>G1.000
rpsA1833808c.267G>C1.000
rpsA1833811c.270G>T1.000
rpsA1833829c.288A>G1.000
rpsA1833832c.291G>A1.000
rpsA1833838c.297G>C1.000
rpsA1833841c.300C>G1.000
rpsA1833847c.306C>G1.000
rpsA1833856c.315A>G1.000
rpsA1833862c.321G>T1.000
rpsA1833894p.Ala118Glu0.981
rpsA1833904c.363G>A1.000
rpsA1833928c.387G>C1.000
rpsA1833949c.408T>C1.000
rpsA1833970c.429G>T1.000
rpsA1833976c.435C>T1.000
rpsA1833979c.438T>C1.000
rpsA1833991c.450C>A1.000
rpsA1834000c.459G>C1.000
rpsA1834009c.468C>T1.000
rpsA1834012c.471G>T0.980
rpsA1834015c.474G>C1.000
rpsA1834021c.480C>T0.981
rpsA1834030c.489C>G1.000
rpsA1834097c.556T>A1.000
rpsA1834102c.561T>C1.000
rpsA1834150c.609G>C1.000
rpsA1834153c.612T>C1.000
rpsA1834154p.Asn205Gln1.000
rpsA1834157c.616T>C1.000
rpsA1834162c.621A>G1.000
rpsA1834165c.624A>G1.000
rpsA1834168c.627C>T1.000
rpsA1834169p.Thr210Ala1.000
rpsA1834177c.636A>C1.000
rpsA1834189c.648G>C1.000
rpsA1834213c.672G>C1.000
rpsA1834234c.693G>C1.000
rpsA1834240c.699T>C1.000
rpsA1834246c.705G>C1.000
rpsA1834249c.708T>C1.000
rpsA1834252c.711C>G1.000
rpsA1834261c.720A>G1.000
rpsA1834264c.723G>C1.000
rpsA1834279c.738C>T1.000
rpsA1834297c.756C>T1.000
rpsA1834303c.762T>G1.000
rpsA1834306c.765T>C1.000
rpsA1834345c.804C>T1.000
rpsA1834348c.807T>C1.000
rpsA1834361c.820T>C1.000
rpsA1834366c.825A>G1.000
rpsA1834396c.855G>C1.000
rpsA1834411c.870T>C1.000
rpsA1834423c.882G>T1.000
rpsA1834451c.910T>C1.000
rpsA1834456c.915T>G1.000
rpsA1834468c.927A>G1.000
rpsA1834489c.948T>C1.000
rpsA1834498c.957C>T1.000
rpsA1834513c.972C>G1.000
rpsA1834520p.Ala327Ser0.976
rpsA1834528c.987T>C1.000
rpsA1834540c.999G>C1.000
rpsA1834543c.1002C>G1.000
rpsA1834546c.1005T>C1.000
rpsA1834558c.1018 1019insAG1.000
tlyA1918629c.690G>C1.000
tlyA1918632c.693G>C1.000
tlyA1918635c.696C>A1.000
katG2155080c.1032C>G1.000
katG2155266c.846A>G0.852
katG2155270p.Ala281Gly0.852
katG2155272c.840C>G0.852
katG2155284c.828A>G0.846
katG2155287c.825G>T0.846
katG2155298p.Phe272Leu1.000
katG2155299c.813A>T1.000
katG2155305c.807A>C1.000
katG2155323c.789C>G0.278
katG2155661p.Val151Leu1.000
katG2155668c.444C>G1.000
katG2155674c.438C>G1.000
katG2155680c.432C>T1.000
katG2155691c.421A>G1.000
katG2155696p.Ala139Val1.000
katG2155716c.396A>C1.000
katG2155722c.390C>G1.000
katG2155728c.384C>G1.000
katG2155742p.Gly124Arg1.000
katG2155747p.Ala122Gly1.000
katG2155749c.363G>A1.000
katG2155752c.360G>A1.000
katG2155766p.His116Val0.289
katG2155769p.Ile115Val0.692
katG2155770c.342G>C0.692
katG2155779c.333G>A0.286
katG2155782c.330G>T0.714
katG2155785c.327A>C0.286
katG2155796p.Ala106Cys0.375
katG2155800c.312C>G0.625
katG2155805p.Ile103Val0.625
katG2155806c.306A>G1.000
katG2155815c.297C>G1.000
katG2155823p.His97Ser0.375
katG2155824c.288G>C0.395
katG2155828p.Tyr95Phe0.361
katG2155836c.276G>C0.361
pncA2289179c.63T>G1.000
pncA2289191c.51G>C1.000
kasA2518219c.105T>C1.000
kasA2518222c.108G>C1.000
kasA2518223c.109T>C1.000
kasA2518231c.117C>A1.000
kasA2518234c.120G>A1.000
kasA2518534c.420G>C1.000
kasA2518564c.450C>G1.000
kasA2518567c.453G>C1.000
kasA2518573c.459G>C1.000
kasA2518574p.Ile154Ala1.000
kasA2518582c.468G>T1.000
kasA2518583p.Gln157Glu1.000
kasA2518588c.474T>C1.000
kasA2518591c.477G>C1.000
kasA2518606c.492G>C1.000
kasA2518609p.Met165Ile1.000
kasA2518612c.498C>T0.971
kasA2518624c.510C>G1.000
kasA2518636c.522C>A0.971
kasA2518639c.525G>T1.000
kasA2518642c.528A>G1.000
kasA2518645c.531G>C1.000
kasA2518656p.Ala181Gly1.000
kasA2518663c.549T>C1.000
kasA2518672c.558G>C1.000
kasA2518678c.564C>T1.000
kasA2518684c.570C>G1.000
kasA2518688p.Val192Phe1.000
kasA2518697p.Cys195Val1.000
kasA2518708c.594C>G1.000
kasA2518714c.600A>C1.000
kasA2518715p.Pro201Gly1.000
kasA2518726c.612G>A1.000
kasA2518732c.618C>G1.000
kasA2518747c.633C>G1.000
kasA2518756c.642G>C1.000
kasA2518780p.Glu222Asp0.968
kasA2518783c.669T>C1.000
kasA2518785p.Glu224Ala1.000
kasA2518787p.Arg225Gly1.000
kasA2518792c.678C>G1.000
kasA2518795c.681C>T1.000
kasA2518813c.699C>T0.972
kasA2518816c.702C>T0.973
kasA2518825c.711T>C1.000
kasA2518843c.729T>C1.000
kasA2518847p.Leu245Met0.971
kasA2518853p.Leu247Ile0.971
kasA2518864c.750G>C1.000
kasA2518877p.Lys255Leu0.972
kasA2518898c.784T>C1.000
kasA2518903c.789C>T0.967
kasA2518906c.792A>G1.000
kasA2518907c.793T>C1.000
kasA2518910p.Leu266Met0.966
kasA2518951c.837G>T0.182
kasA2518954c.840C>G0.182
kasA2519158c.1044C>T1.000
kasA2519173c.1059C>G1.000
kasA2519183c.1069C>T1.000
kasA2519194c.1080G>C1.000
kasA2519195p.Thr361Ala1.000
kasA2519198c.1084C>T0.262
kasA2519203c.1089C>T0.262
kasA2519209c.1095C>G0.262
kasA2519212c.1098C>G0.262
kasA2519218c.1104G>T0.275
kasA2519224c.1110C>G1.000
kasA2519227c.1113G>C1.000
kasA2519242c.1128C>G1.000
kasA2519248c.1134C>T1.000
kasA2519255p.Asp381Asn1.000
kasA2519260c.1146T>C1.000
kasA2519263c.1149C>T1.000
kasA2519266c.1152C>G1.000
kasA2519269c.1155C>T1.000
kasA2519272c.1158C>G1.000
kasA2519278c.1164A>G1.000
kasA2519281c.1167G>T1.000
kasA2519284c.1170C>T1.000
kasA2519293c.1179T>C1.000
kasA2519297p.Arg395Lys1.000
kasA2519305c.1191A>C1.000
kasA2519306p.Val398Ile1.000
kasA2519323c.1209G>A1.000
kasA2519344c.1230G>C1.000
kasA2519347c.1233T>G1.000
folC2746957c.642C>G1.000
folC2746960c.639G>C1.000
folC2746967p.Gly211Glu1.000
folC2746977p.Asp208Thr1.000
folC2746979p.Ala207Asp1.000
folC2746987c.612A>G1.000
folC2746995p.Val202Thr1.000
folC2746999c.600A>G1.000
folC2747002c.597A>G1.000
folC2747007p.Ser198Gly1.000
folC2747023c.576G>C1.000
folC2747029c.570C>G1.000
folC2747032c.567T>G1.000
folC2747040p.Ile187Val1.000
folC2747041c.558C>G1.000
folC2747134c.465G>C0.217
thyX3067319c.627C>G1.000
thyX3067325c.621T>C1.000
thyX3067331c.615G>A1.000
thyX3067334c.612G>T0.933
thyX3067349c.597C>G1.000
thyX3067355c.591T>C1.000
thyX3067367c.579C>G1.000
thyX3067376c.570C>G1.000
thyX3067403c.543G>C1.000
thyX3067415c.531G>A1.000
thyX3067423c.523G>A1.000
thyX3067424c.522C>T1.000
thyX3067430c.516G>C1.000
thyX3067436c.510G>C1.000
thyX3067439c.507T>C1.000
thyX3067442c.504G>C1.000
thyX3067457c.489G>A1.000
thyX3067465p.Ile161Val1.000
thyX3067466c.480C>G1.000
thyX3067475c.471T>C1.000
thyX3067765p.Leu61Ile1.000
thyX3067771p.Gly59Ser1.000
thyX3067772c.174G>C1.000
thyX3067781c.165G>C1.000
thyX3067788p.Lys53Arg1.000
thyX3067808c.138G>A1.000
thyX3067814c.132A>G1.000
thyX3067817c.129G>A1.000
thyX3067820c.126G>C1.000
thyX3067825c.121G>T1.000
thyX3067829c.117G>T1.000
thyX3067840p.Val36Thr1.000
thyX3067841c.105C>G1.000
thyX3067847c.99G>A1.000
thyX3067850c.96T>C1.000
thyX3067862c.84G>A1.000
thyX3067869p.Thr26Ser1.000
thyX3067874c.72G>C1.000
thyX3067883c.63G>A1.000
thyX3067886c.60T>C1.000
thyX3067889c.57G>C1.000
thyX3067894p.Leu18Gln1.000
thyX3067898p.Asp16Glu1.000
thyX3067901c.45G>C1.000
thyX3067916c.30T>C1.000
thyX3067935p.Thr4Ile1.000
thyA3073863c.609A>G1.000
thyA3073874p.Ile200Val1.000
thyA3073902c.570G>T1.000
thyA3073905c.567G>A1.000
thyA3073920c.552G>C1.000
thyA3073925c.547A>G1.000
thyA3073926c.546C>G1.000
thyA3073929c.543A>G1.000
thyA3073953c.519A>G1.000
thyA3073959c.513A>G1.000
thyA3073962c.510C>G1.000
thyA3073971c.501G>A1.000
thyA3073977c.495T>C1.000
thyA3073983c.489G>C1.000
thyA3073989c.483A>G1.000
thyA3073994c.478C>G1.000
thyA3074000p.Arg158Lys1.000
thyA3074004c.468A>G1.000
thyA3074013c.459G>A1.000
thyA3074031c.441A>G1.000
thyA3074034c.438A>G1.000
thyA3074037c.435G>C1.000
thyA3074046c.426C>T1.000
thyA3074053p.Arg140Gln1.000
thyA3074057p.Glu139Pro1.000
thyA3074058c.414G>A1.000
thyA3074061c.411T>C1.000
thyA3074082c.390C>G1.000
thyA3074089p.Ile128Asn1.000
thyA3074094c.378C>G1.000
thyA3074097c.375G>C1.000
thyA3074160c.312T>C1.000
thyA3074165p.Ala103Thr1.000
thyA3074175c.297T>C1.000
thyA3074184c.288T>A1.000
thyA3074187c.285A>G1.000
thyA3074195p.Ile93Val1.000
thyA3074196c.276C>G1.000
thyA3074199c.273C>T1.000
thyA3074205p.Glu89Asp1.000
thyA3074214p.Asp86Glu1.000
thyA3074220c.252T>G1.000
thyA3074229c.243G>A1.000
thyA3074238c.234G>C1.000
thyA3074244c.228T>A1.000
thyA3074250p.Glu74Asp1.000
thyA3074253p.His73Gln1.000
thyA3074264p.Gly70Arg1.000
thyA3074267p.Ile69Val1.000
thyA3074268c.204A>G1.000
thyA3074271c.201G>C1.000
thyA3074286c.186A>G1.000
ald3087699p.Leu294Val1.000
ald3087704c.885T>C1.000
ald3087716c.897G>C1.000
ald3087727p.Ala303Gly1.000
ald3087738p.Lys307Arg1.000
ald3087751p.Tyr311Phe1.000
ald3087767c.948G>C1.000
ald3087770c.951G>C1.000
ald3087779c.960T>C1.000
fbiA3641073c.531T>C1.000
fbiA3641085c.543G>C1.000
fbiA3641086p.Thr182Ser1.000
fbiA3641100c.558T>G1.000
fbiA3641103c.561T>C1.000
alr3840230c.1191A>C1.000
alr3840236c.1185T>C1.000
alr3840262p.His387Asn1.000
alr3840274p.Val383Leu1.000
alr3840275c.1146A>C1.000
alr3840278p.Asp381Glu1.000
panD4044057c.225G>T1.000
panD4044072c.210G>C1.000
panD4044075c.207A>G1.000
panD4044085p.Ser66Thr1.000
panD4044090c.192G>A1.000
panD4044093c.189T>C1.000
panD4044105c.177C>G1.000
panD4044120c.162T>C1.000
panD4044123c.159A>G1.000
panD4044126c.156A>T1.000
panD4044138c.144A>G1.000
panD4044147c.135G>C1.000
panD4044150c.132T>C1.000
panD4044156c.126T>C1.000
panD4044165c.117C>G1.000
panD4044177c.105G>C1.000
panD4044180p.Asp34Glu1.000
panD4044188c.94A>G1.000
panD4044189c.93G>A1.000
panD4044195c.87A>G1.000
panD4044210c.72G>A1.000
panD4044213c.69G>C1.000
panD4044258c.24C>G1.000
panD4044261c.21C>T1.000
embC4240717c.855T>C1.000
embC4240777c.915G>A1.000
embC4240780c.918T>C1.000
embC4240783c.921G>C1.000
embC4240789c.927T>C1.000
embC4240819c.957A>C1.000
embC4240828c.966G>A1.000
embC4240831c.969T>G1.000
embC4240867c.1005T>G1.000
embC4241017c.1155T>C1.000
embC4241023c.1161T>G1.000
embC4241024p.Val388Phe1.000
embC4241038c.1176G>C1.000
embC4241039p.Asp393Asn1.000
embC4241047c.1185C>G1.000
embC4241050c.1188T>G1.000
embC4241053c.1191G>C1.000
embC4241059c.1197G>A1.000
embC4241074c.1212G>C1.000
embC4241095c.1233C>T1.000
embC4241104c.1242G>A0.978
embC4241107c.1245G>C0.977
embC4241109p.Ala416Gly1.000
embC4241416c.1554C>G1.000
embC4241420p.Glu520Ser1.000
embC4241433p.Met524Thr1.000
embC4241435p.Ala525Ser1.000
embC4241453p.Ile531Val1.000
embC4241458c.1596C>G1.000
embC4241533c.1671T>C1.000
embC4241536c.1674A>C1.000
embC4241545c.1683T>G1.000
embC4241548c.1686T>A1.000
embC4241551c.1689A>C1.000
embC4241560c.1698C>G1.000
embC4241572c.1710C>T0.533
embC4241584c.1722T>C1.000
embC4241587c.1725C>G1.000
embC4241593c.1731C>G1.000
embC4241611c.1749G>C0.619
embC4241614c.1752A>C1.000
embC4241626c.1764T>C1.000
embC4241635c.1773G>C1.000
embC4241644c.1782G>C1.000
embC4241648c.1786T>C1.000
embC4241656c.1794G>A1.000
embC4241659c.1797G>C1.000
embC4241665c.1803G>T1.000
embC4241668c.1806G>C1.000
embC4241671c.1809T>G1.000
embC4241691p.Gly610Ala1.000
embC4241695c.1833T>G1.000
embC4241750p.Leu630Met1.000
embC4241756c.1894C>T1.000
embC4241767c.1905C>G1.000
embC4241769p.Ser636Thr1.000
embC4241791c.1929G>C0.784
embC4241794c.1932C>G0.778
embC4241809c.1947A>C1.000
embC4242826c.2964G>C1.000
embC4242832c.2970A>G1.000
embC4242838c.2976C>G1.000
embC4242844c.2982A>G1.000
embC4242847c.2985C>G1.000
embC4242859c.2997C>T1.000
embC4242862c.3000A>G1.000
embC4242872p.Asp1004Thr1.000
embC4242878p.Thr1006Val1.000
embC4242907c.3045G>C1.000
embC4242919c.3057A>G1.000
embC4242928c.3066A>G1.000
embA4244645c.1413T>C1.000
embA4244648c.1416G>C0.727
embA4244665p.Thr478Ser0.754
embA4244669c.1437G>C1.000
embA4244681c.1449A>C1.000
embA4244684c.1452C>G1.000
embA4244695p.Lys488Thr1.000
embA4244712p.Ala494Ser1.000
embA4244726p.Asp498Glu1.000
embA4244747c.1515T>G1.000
embA4244878p.Ala549Val1.000
embA4244885c.1653A>G0.967
embA4244897c.1665T>C1.000
embA4244900c.1668G>C1.000
embA4244903c.1671G>C1.000
embA4244904p.Val558Ile1.000
embA4244909c.1677C>T1.000
embA4244920c.1689 1690insG1.000
embB4246869p.Ser119Asn1.000
embB4246874p.Gln121Lys1.000
embB4246882c.369G>C0.536
embB4246886p.Val125Ile0.536
embB4247389c.876C>G1.000
embB4247398c.885G>A1.000
embB4247401c.888T>C1.000
embB4247407c.894G>C1.000
embB4247426p.Gly305Gln1.000
embB4247434c.921C>G1.000
embB4247437c.924A>C1.000
embB4247440c.927C>G1.000
embB4247449c.936C>T1.000
embB4247455c.942C>T1.000
embB4247464c.951C>G1.000
embB4247470c.957T>C1.000
embB4247491c.978G>C1.000
embB4247497c.984T>C1.000
embB4247511p.Tyr333Phe0.975
embB4247527c.1014G>C1.000
embB4247536c.1023C>A0.966
embB4247554c.1041T>C1.000
embB4247555p.Leu348Ile1.000
embB4247566c.1053C>A1.000
embB4247572c.1059A>C1.000
embB4247590c.1077A>G1.000
embB4247629c.1116C>G1.000
embB4247638c.1125G>C1.000
embB4247716c.1203C>A0.433
embB4247968c.1455C>G1.000
embB4247977c.1464C>G1.000
embB4247992c.1479G>C1.000
embB4248001c.1488C>T1.000
embB4248063p.Ala517Glu1.000
embB4248070c.1557T>C1.000
embB4248085c.1572T>C1.000
embB4248088c.1575C>T1.000
embB4248097c.1584C>G1.000
embB4248112c.1599C>G1.000
embB4248118c.1605T>C1.000
embB4248130c.1617G>C1.000
embB4248133c.1620C>G1.000
embB4248142c.1629T>C1.000
embB4248143p.Leu544Ile1.000
embB4248157c.1644A>G1.000
embB4248158p.Cys549Ser1.000
embB4248167p.Thr552Ala1.000
embB4248170p.Ala553Ser0.980
embB4248173p.Val554Leu1.000
embB4248199c.1686A>G1.000
embB4248200p.Ile563Val1.000
embB4248206p.Ser565Gly1.000
embB4248220c.1707A>G1.000
embB4248225p.Ala571Val1.000
embB4248242p.Val577Ile1.000
embB4248252p.Gly580Ala1.000
embB4248256c.1743C>G1.000
embB4248264p.Phe584Cys1.000
embB4248277c.1764G>C1.000
embB4248304c.1791G>C0.926
embB4248319c.1806A>G1.000
embB4248322c.1809G>T1.000
embB4248457c.1944T>C0.390
embB4248460c.1947C>G0.377
embB4248472c.1959T>C0.356
embB4249525c.3012T>C0.333
embB4249528c.3015C>T0.333
embB4249529p.Ile1006Val0.333
embB4249532p.Ala1007Thr0.333
embB4249648c.3135G>C1.000
embB4249651c.3138C>G0.914
embB4249661p.Ala1050Pro0.923
embB4249666c.3153C>T0.927
embB4249686p.Ala1058Gly1.000
embB4249693c.3180T>C1.000
ethA4326850c.624T>C0.606
ethA4326861c.613G>A0.255
ethA4326865c.609C>G0.255
ethA4327396c.78A>G1.000
ethA4327405c.69C>G1.000
ethA4327419p.Ala19Thr1.000
gid4408253c.-51A>G1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
This tool is for Research Use Only and is offered free for use. The London School of Hygiene and Tropical Medicine shall have no liability for any loss or damages of any kind, however sustained relating to the use of this tool.
© 2019 London School of Hygiene and Tropical Medicine;