TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5ccbf5cc737b7
Sample: 5ccbf5cc737b7

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Summary
ID: 5ccbf5cc737b7
Date: Fri May 3 09:05:39 2019
Strain: lineage4.1.2;lineage1.2.2
Drug-resistance: Sensitive

Drug1ResistanceSupporting Mutations (frequency)
Isoniazid
Rifampicin
Ethambutol
Pyrazinamide
Streptomycin
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage4.1.2Euro-American (X-type)T;HNone
lineage1.2.2Indo-OceanicEAI1RD239

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB5320c.81C>T1.000
gyrB5326c.87T>C1.000
gyrB5329c.90C>G1.000
gyrB5341c.102T>C1.000
gyrB5344c.105C>T1.000
gyrB5347c.108G>C1.000
gyrB5359c.120C>G1.000
gyrB5363c.124T>C1.000
gyrB5371c.132T>C1.000
gyrB5374c.135C>G1.000
gyrB5377c.138T>C1.000
gyrB5386c.147G>C1.000
gyrB5389c.150C>G1.000
gyrB6086p.Thr283Pro1.000
gyrB6097c.858G>A1.000
gyrB6100c.861G>C1.000
gyrB6109c.870G>C1.000
gyrB6115c.876A>G1.000
gyrB6123p.Ala295Gly1.000
gyrB6127c.888G>T1.000
gyrB6130c.891T>C1.000
gyrB6133c.894G>C1.000
gyrB6175c.936G>A1.000
gyrB6181c.942C>A1.000
gyrB6184c.945C>T1.000
gyrB6196c.957C>T1.000
gyrB6203p.Ser322Ala1.000
gyrB6209c.970C>T1.000
gyrB6215c.976T>A1.000
gyrB6227p.Lys330Arg1.000
gyrB6241p.Asp334Glu1.000
gyrB6242p.Arg335Lys1.000
gyrB6250c.1011A>T1.000
gyrB6253c.1014G>C1.000
gyrB6265c.1026C>T1.000
gyrB6283p.Asp348Glu1.000
gyrB6286c.1047T>C1.000
gyrB6292c.1053G>C1.000
gyrB6295c.1056A>G1.000
gyrB6298c.1059C>T1.000
gyrB6307c.1068T>G1.000
gyrB6319c.1080G>C0.394
gyrB6325c.1086C>G0.355
gyrB6326c.1087A>T0.355
gyrB6329p.Glu364Gln0.355
gyrB6346c.1107C>T1.000
gyrB6352c.1113C>G1.000
gyrB6523c.1284G>C1.000
gyrB6526c.1287T>C1.000
gyrB6532c.1293C>T1.000
gyrB6547c.1308T>C1.000
gyrB6550c.1311A>T1.000
gyrB6551c.1312T>C1.000
gyrB6571c.1332T>C1.000
gyrB6577c.1338T>C1.000
gyrB6583c.1344G>C1.000
gyrB6589c.1350G>C1.000
gyrB6590p.Arg451Ser1.000
gyrB6601c.1362A>G1.000
gyrB6607c.1368T>C1.000
gyrB6610c.1371C>G1.000
gyrB6613c.1374A>G1.000
gyrB6616c.1377A>G1.000
gyrB6628c.1389C>A1.000
gyrB6634c.1395T>C1.000
gyrB6637c.1398T>G1.000
gyrB6640c.1401A>C1.000
gyrB6643c.1404A>G1.000
gyrB6649c.1410T>C1.000
gyrB6652c.1413C>T1.000
gyrB6655c.1416T>C1.000
gyrB6673c.1434A>C1.000
gyrB6676c.1437T>G1.000
gyrB6685c.1446C>A1.000
gyrB6700c.1461T>C1.000
gyrB6703c.1464G>C1.000
gyrB6706c.1467G>A1.000
gyrB6709c.1470A>G1.000
gyrB6727c.1488G>T1.000
gyrB6728c.1489C>T1.000
gyrB6745c.1506T>C1.000
gyrB6751c.1512G>C1.000
gyrB6760c.1521G>C1.000
gyrB6769c.1530C>T1.000
gyrB6775c.1536G>C1.000
gyrB6793c.1554T>C1.000
gyrB6797p.Gly520Thr1.000
gyrB6808c.1569C>T1.000
gyrB6811c.1572C>T1.000
gyrB6838c.1599C>G1.000
gyrB6841c.1602T>C1.000
gyrB6844c.1605T>G1.000
gyrB6853c.1614A>G1.000
gyrB6856c.1617T>C0.929
gyrB6859c.1620T>C1.000
gyrB6865c.1626G>A1.000
gyrB6869c.1630T>C1.000
gyrB6872c.1633T>C1.000
gyrB6878c.1639T>C1.000
gyrB6881c.1642T>C1.000
gyrB6896p.Arg553Lys1.000
gyrB6910c.1671G>A1.000
gyrB6911p.Asn558His1.000
gyrB6916c.1677G>C1.000
gyrB6919c.1680T>C1.000
gyrB6925c.1686T>C1.000
gyrB6926c.1687T>C1.000
gyrB6931c.1692A>C1.000
gyrB6934c.1695A>G1.000
gyrB6955c.1716G>A1.000
gyrB6970p.Asp577Glu1.000
gyrB6982c.1743A>C1.000
gyrB7012c.1773G>C1.000
gyrB7108c.1869G>A1.000
gyrB7123c.1884C>G1.000
gyrB7126c.1887G>A0.969
gyrB7129c.1890T>G1.000
gyrB7132c.1893T>G1.000
gyrB7153c.1914G>T1.000
gyrB7156c.1917C>T1.000
gyrB7159c.1920C>T1.000
gyrB7162c.1923C>T1.000
gyrB7165c.1926C>T1.000
gyrB7168c.1929C>G1.000
gyrB7178c.1939T>C1.000
gyrB7210p.Asp657Glu1.000
gyrB7213c.1974G>A1.000
gyrB7225c.1986T>C1.000
gyrB7234c.1995C>T1.000
gyrB7243c.2004G>A1.000
gyrB7246c.2007T>C1.000
gyrA7343c.42G>T1.000
gyrA7355c.54T>C1.000
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T1.000
gyrA7394c.93T>C1.000
gyrA7397c.96G>C1.000
gyrA7406c.105G>C1.000
gyrA7412c.111C>G1.000
gyrA7418c.117C>T1.000
gyrA7433c.132G>A1.000
gyrA7442c.141G>C1.000
gyrA7457c.156T>C1.000
gyrA7463c.162G>C1.000
gyrA7472c.171T>C1.000
gyrA7475c.174A>G1.000
gyrA7480p.Phe60Tyr1.000
gyrA7484c.183T>C1.000
gyrA7499c.198G>C1.000
gyrA7526c.225G>C1.000
gyrA7532c.231T>G1.000
gyrA7541c.240C>G1.000
gyrA7547c.246C>T1.000
gyrA7565c.264C>T1.000
gyrA7569p.Ala90Ser1.000
gyrA7585p.Ser95Thr1.000
gyrA7592c.291G>C1.000
gyrA7595c.294C>G1.000
gyrA7601c.300C>T0.973
gyrA7607c.306C>G1.000
gyrA7613c.312G>A1.000
gyrA7622c.321C>T1.000
gyrA7631c.330G>C1.000
gyrA7637c.336C>T1.000
gyrA7652c.351C>T1.000
gyrA7658c.357A>G1.000
gyrA7661c.360C>T1.000
gyrA7664c.363T>C1.000
gyrA7667c.366C>T1.000
gyrA7670c.369A>G1.000
gyrA7673c.372G>A1.000
gyrA7676c.375G>C1.000
gyrA7679c.378G>C1.000
gyrA7683c.382A>C1.000
gyrA7694c.393A>G1.000
gyrA7697c.396C>G1.000
gyrA7706c.405C>T1.000
gyrA7709c.408G>C1.000
gyrA7710c.409T>C1.000
gyrA7728c.427A>C1.000
gyrA7763c.462T>G1.000
gyrA7775c.474C>T1.000
gyrA7784c.483A>G1.000
gyrA7790c.489G>C1.000
gyrA7796c.495G>T1.000
gyrA7799c.498A>G1.000
gyrA7802c.501C>G1.000
gyrA7832c.531G>T1.000
gyrA7835c.534A>G1.000
gyrA7841c.540C>T1.000
gyrA7847c.546G>C1.000
gyrA7859c.558A>C1.000
gyrA7865c.564T>C1.000
gyrA7886c.585T>G1.000
gyrA8156c.855T>C1.000
gyrA8168c.867A>G1.000
gyrA8174c.873C>G1.000
gyrA8177c.876A>C1.000
gyrA8191p.Ala297Gly1.000
gyrA8198c.897T>C1.000
gyrA8207c.906T>C1.000
gyrA8210c.909G>A0.977
gyrA8219c.918T>C1.000
gyrA8222c.921C>T1.000
gyrA8225c.924T>C1.000
gyrA8235c.934T>C1.000
gyrA8240c.939C>A0.952
gyrA8243c.942C>T1.000
gyrA8246c.945C>G1.000
gyrA8247p.Ile316Val1.000
gyrA8252c.951G>A1.000
gyrA8253p.Ile318Leu1.000
gyrA8267c.966G>C1.000
gyrA8283p.Ile328Leu1.000
gyrA8288c.987T>C1.000
gyrA8294c.993T>C1.000
gyrA8324c.1023T>C1.000
gyrA8327c.1026C>G1.000
gyrA8339c.1038A>G1.000
gyrA8340p.Ala347Ser1.000
gyrA8354c.1053G>C1.000
gyrA8366c.1065G>C1.000
gyrA8372c.1071G>T1.000
gyrA8390c.1089C>G1.000
gyrA8391p.Tyr364Leu1.000
gyrA8399c.1098T>G1.000
gyrA8408c.1107A>G1.000
gyrA8414c.1113C>T1.000
gyrA8420c.1119T>C1.000
gyrA8433p.Thr378Arg1.000
gyrA8442c.1141C>T1.000
gyrA8453c.1152A>C1.000
gyrA8456c.1155C>T1.000
gyrA8459c.1158G>A1.000
gyrA8462c.1161A>G1.000
gyrA8471c.1170T>C0.944
gyrA8480c.1179C>T1.000
gyrA8486c.1185T>C1.000
gyrA8504c.1203G>C1.000
gyrA8510c.1209G>A1.000
gyrA8513c.1212C>G1.000
gyrA8516c.1215T>C1.000
gyrA8519c.1218A>G1.000
gyrA8520c.1219C>T1.000
gyrA8535p.Glu412Gln1.000
gyrA8540c.1239C>T1.000
gyrA8546p.Asp415Glu1.000
gyrA8561c.1260A>C1.000
gyrA8571c.1270C>T1.000
gyrA8603c.1302A>C1.000
gyrA8619c.1318T>C1.000
gyrA8624c.1323G>C1.000
gyrA8627c.1326C>G1.000
gyrA8628c.1327C>T1.000
gyrA8633c.1332C>T1.000
gyrA8636c.1335A>C1.000
gyrA8645c.1344C>A1.000
gyrA8649p.Arg450Lys1.000
gyrA8655p.Ile452Val1.000
gyrA8663c.1362C>T1.000
gyrA8672c.1371A>G1.000
gyrA8678c.1377G>A0.970
gyrA8696c.1395G>C1.000
gyrA8699c.1398A>G1.000
gyrA8705c.1404C>T1.000
gyrA8711c.1410A>C1.000
gyrA8714c.1413A>G1.000
gyrA8723c.1422G>T1.000
gyrA8726c.1425G>A1.000
gyrA8729c.1428T>C1.000
gyrA8731p.Gly477Ala1.000
gyrA8740p.Arg480His0.500
gyrA8756c.1455A>G0.429
gyrA8757p.Ile486Leu0.429
gyrA8810c.1509A>T1.000
gyrA8813p.Asp504Glu1.000
gyrA8816c.1515C>G1.000
gyrA8828c.1527T>C1.000
gyrA8829c.1528T>C1.000
gyrA8837c.1536C>G1.000
gyrA8840c.1539C>T1.000
gyrA8852c.1551T>C1.000
gyrA8858c.1557T>G1.000
gyrA8867c.1566A>G1.000
gyrA8870c.1569G>C1.000
gyrA8873c.1572A>G1.000
gyrA8876c.1575C>T1.000
gyrA8897c.1596T>C1.000
gyrA8903c.1602T>C1.000
gyrA8915c.1614A>G1.000
gyrA8939c.1638T>C1.000
gyrA8942c.1641G>C1.000
gyrA8945c.1644G>A1.000
gyrA8946c.1645T>C1.000
gyrA8952p.Gln551Ala1.000
gyrA8967p.Ala556Asn1.000
gyrA8981c.1680G>C1.000
gyrA8987c.1686C>G1.000
gyrA8998p.Leu566Trp1.000
gyrA9017c.1716C>G1.000
gyrA9023c.1722A>C1.000
gyrA9029c.1728T>G1.000
gyrA9032c.1731T>C1.000
gyrA9038c.1737C>A1.000
gyrA9050p.Asp583Glu1.000
gyrA9056c.1755C>G1.000
gyrA9200c.1899A>G1.000
gyrA9213p.Thr638Val1.000
gyrA9230c.1929T>C1.000
gyrA9236c.1935G>C1.000
gyrA9242c.1941A>C1.000
gyrA9251c.1950G>C1.000
gyrA9252p.Val651Ile1.000
gyrA9267p.Asn656Gly0.826
gyrA9275c.1974G>A0.714
gyrA9293c.1992G>C0.862
gyrA9296c.1995T>C1.000
gyrA9304p.Gly668Asp1.000
gyrA9323c.2022C>G1.000
gyrA9324c.2023T>A1.000
gyrA9335c.2034G>T1.000
gyrA9341c.2040C>G1.000
gyrA9345c.2044A>C1.000
gyrA9353c.2052G>C1.000
gyrA9356c.2055G>A1.000
gyrA9374c.2073G>T1.000
gyrA9377c.2076A>G1.000
gyrA9383c.2082T>C1.000
gyrA9407c.2106C>T1.000
gyrA9419c.2118T>C1.000
gyrA9420p.Ile707Glu1.000
gyrA9626c.2325T>C1.000
gyrA9630p.Val777Ile1.000
gyrA9635c.2334T>C1.000
gyrA9641c.2340C>T1.000
gyrA9644c.2343T>C1.000
gyrA9650c.2349G>C1.000
gyrA9656c.2355C>G1.000
gyrA9662c.2361G>C1.000
gyrA9668c.2367C>T1.000
gyrA9683c.2382G>T1.000
gyrA9689c.2388G>T1.000
gyrA9701c.2400T>C1.000
gyrA9707c.2406G>C1.000
gyrA9716c.2415T>C1.000
gyrA9738p.Leu813Ile1.000
gyrA9743c.2442C>G1.000
gyrA9746c.2445C>T0.364
rpoB759788c.-19A>G1.000
rpoB759929c.123A>G1.000
rpoB759944c.138A>G1.000
rpoB759947c.141C>A1.000
rpoB759950c.144T>C1.000
rpoB759956c.150C>T1.000
rpoB759968c.162G>C1.000
rpoB759974p.Glu56Asp1.000
rpoB760046c.240G>C1.000
rpoB760059p.Tyr85Glu1.000
rpoB760067c.261G>C1.000
rpoB760070c.264T>C1.000
rpoB760082c.276C>T1.000
rpoB760088c.282C>G1.000
rpoB760091c.285G>C0.581
rpoB760101c.295T>C0.567
rpoB760104c.298T>A0.567
rpoB760112c.306T>C1.000
rpoB760118c.312T>G1.000
rpoB760121c.315T>C1.000
rpoB760130p.Asp108Glu1.000
rpoB760136c.330G>A1.000
rpoB760139c.333A>T1.000
rpoB760142c.336C>G1.000
rpoB760181c.375T>C1.000
rpoB760184c.378A>G1.000
rpoB760196c.390C>G1.000
rpoB760235c.429T>C1.000
rpoB760244c.438G>C1.000
rpoB760283c.477G>C1.000
rpoB760298c.492G>C1.000
rpoB760310c.504G>C1.000
rpoB760316c.510C>G1.000
rpoB760325c.519G>C1.000
rpoB760331c.525G>C1.000
rpoB760334c.528G>T1.000
rpoB760340c.534G>T1.000
rpoB760357p.Thr184Ser1.000
rpoB760361c.555T>C1.000
rpoB760376p.Asp190Glu1.000
rpoB760406c.600G>C0.971
rpoB760407p.Ser201Gly1.000
rpoB760415c.609C>T1.000
rpoB760424c.618C>G1.000
rpoB760430c.624T>C1.000
rpoB760457c.651C>T1.000
rpoB760463c.657C>T1.000
rpoB760475c.669A>G1.000
rpoB760478c.672C>T1.000
rpoB760481c.675G>T1.000
rpoB760484c.678A>G1.000
rpoB760502c.696C>G1.000
rpoB760522p.Ser239Asn0.974
rpoB760532c.726T>C1.000
rpoB760533p.Val243Thr1.000
rpoB760541c.735G>C1.000
rpoB760547c.741G>C1.000
rpoB760567p.Ser254Trp1.000
rpoB760571c.765G>C1.000
rpoB760585p.Asn260Ser1.000
rpoB760591p.Val262Ala1.000
rpoB760595c.789C>T1.000
rpoB760596p.Thr264Pro1.000
rpoB760611c.805T>C1.000
rpoB760646c.840C>G1.000
rpoB760655c.849A>G1.000
rpoB760661c.855A>C1.000
rpoB760670c.864G>C1.000
rpoB760674c.868T>C1.000
rpoB760679c.873A>G1.000
rpoB760683c.877T>C0.984
rpoB760721c.915C>G1.000
rpoB760724c.918T>C1.000
rpoB760730c.924T>C1.000
rpoB760748c.942C>G1.000
rpoB760751c.945G>C1.000
rpoB760755p.His317Asn1.000
rpoB760759p.Val318Ala1.000
rpoB760764p.Glu320Gln1.000
rpoB760769c.963C>G1.000
rpoB760784c.978G>T0.979
rpoB760793c.987A>G1.000
rpoB760805c.999G>C1.000
rpoB760817c.1011A>G1.000
rpoB760820c.1014T>C1.000
rpoB760826c.1020C>G1.000
rpoB760830c.1024T>C1.000
rpoB760841c.1035T>C1.000
rpoB760859c.1053T>C1.000
rpoB760862c.1056G>C1.000
rpoB760877c.1071G>T1.000
rpoB760883c.1077G>C1.000
rpoB760886c.1080A>G1.000
rpoB760887p.Thr361Val1.000
rpoB760910c.1104C>T1.000
rpoB760916c.1110C>T1.000
rpoB760919c.1113C>T1.000
rpoB760925c.1119T>C1.000
rpoB760928c.1122G>T1.000
rpoB760931c.1125C>G1.000
rpoB760946c.1140A>G1.000
rpoB760965p.Met387Leu1.000
rpoB760970c.1164G>C1.000
rpoB760973c.1167G>C1.000
rpoB760982c.1176G>C1.000
rpoB760985c.1179G>C1.000
rpoB760988c.1182C>G1.000
rpoB760991c.1185G>T1.000
rpoB760997c.1191G>C1.000
rpoB761015c.1209G>C1.000
rpoB761027c.1221A>C1.000
rpoB761036c.1230G>C1.000
rpoB761037c.1231T>C1.000
rpoB761051c.1245G>T1.000
rpoB761054c.1248G>C1.000
rpoB761057c.1251G>C1.000
rpoB761060c.1254C>G1.000
rpoB761063c.1257C>G1.000
rpoB761084c.1278C>A1.000
rpoB761087c.1281C>G1.000
rpoB761088c.1282A>T1.000
rpoB761097c.1291A>T1.000
rpoB761102c.1296A>G1.000
rpoB761111c.1305C>T1.000
rpoB761132c.1326G>T1.000
rpoB761133c.1327T>C1.000
rpoB761150c.1344A>T1.000
rpoB761165c.1359G>C1.000
rpoB761180c.1374A>C1.000
rpoB761189c.1383T>C1.000
rpoB761195c.1389G>C1.000
rpoB761198c.1392G>T0.955
rpoB761213c.1407G>C1.000
rpoB761217p.Pro471Ser0.950
rpoB761234c.1428G>C1.000
rpoB761249c.1443A>G1.000
rpoB761261c.1455G>T1.000
rpoB761264c.1458C>G1.000
rpoB761282c.1476C>T1.000
rpoB761288c.1482G>T1.000
rpoB761318c.1512G>T1.000
rpoB761327c.1521A>G1.000
rpoB761330c.1524G>C1.000
rpoB761345c.1539G>C1.000
rpoB761354c.1548C>T1.000
rpoB761360c.1554T>C1.000
rpoB761362p.Ser519Thr1.000
rpoB761367p.Glu521Gln1.000
rpoB761374p.Val523Asp1.000
rpoB761408c.1602G>C1.000
rpoB761414c.1608A>G1.000
rpoB761423c.1617T>C1.000
rpoB761537c.1731C>G1.000
rpoB761552c.1746G>C1.000
rpoB761555c.1749G>C1.000
rpoB761558c.1752C>G1.000
rpoB761570c.1764T>C0.943
rpoB761573c.1767C>G0.943
rpoB761579c.1773G>C1.000
rpoB761606c.1800C>G1.000
rpoB761612c.1806G>T1.000
rpoB761615c.1809A>C1.000
rpoB761636c.1830G>T1.000
rpoB761645c.1839C>G1.000
rpoB761648c.1842T>C1.000
rpoB761666c.1860G>C1.000
rpoB761669c.1863C>T1.000
rpoB761675c.1869G>T1.000
rpoB761690c.1884G>C1.000
rpoB761708c.1902C>T1.000
rpoB761712p.Val636Ile1.000
rpoB761717c.1912 1912del1.000
rpoB761722r.1916a>g1.000
rpoC763375c.6C>A0.983
rpoC763408c.39T>C1.000
rpoC763411c.42T>C1.000
rpoC763414c.45T>C1.000
rpoC763423p.Glu18Asp1.000
rpoC763430c.61A>C1.000
rpoC763433p.Gln22Asn1.000
rpoC763443p.Tyr25Phe1.000
rpoC763456c.87A>G1.000
rpoC763468c.99G>C1.000
rpoC763486c.117T>C1.000
rpoC763492c.123G>T1.000
rpoC763528c.159G>A1.000
rpoC763546c.177A>G1.000
rpoC763558c.189C>T1.000
rpoC763570c.201G>C1.000
rpoC763573c.204G>C1.000
rpoC763594c.225C>T1.000
rpoC763603c.234C>T1.000
rpoC763615c.246G>C1.000
rpoC763618c.249C>T1.000
rpoC763633c.264T>C0.786
rpoC763660c.291T>G1.000
rpoC763666c.297G>A1.000
rpoC763675c.306C>G1.000
rpoC763702c.333C>G1.000
rpoC763705c.336G>A1.000
rpoC763709c.340C>T1.000
rpoC763714c.345G>C1.000
rpoC763717c.348T>C1.000
rpoC763723c.354G>C1.000
rpoC763732c.363C>T1.000
rpoC763741c.372C>T1.000
rpoC763747c.378G>A1.000
rpoC763765c.396T>G1.000
rpoC763792p.Glu141Asp1.000
rpoC763807c.438T>C1.000
rpoC763813c.444C>G1.000
rpoC763831c.462A>G1.000
rpoC763837c.468G>C1.000
rpoC763840c.471G>C1.000
rpoC763858c.489A>G1.000
rpoC763861c.492C>T0.968
rpoC763872p.Gly168Ala1.000
rpoC763876p.Glu169Asp1.000
rpoC763879c.510A>G1.000
rpoC763882c.513G>A1.000
rpoC763891c.522G>C1.000
rpoC763894c.525A>G1.000
rpoC763900c.531G>C1.000
rpoC763921c.552G>C1.000
rpoC763924c.555G>A1.000
rpoC763930c.561G>A1.000
rpoC763933c.564C>T1.000
rpoC763940p.Ala191Ser1.000
rpoC763945c.576T>C1.000
rpoC763947p.Ala193Val1.000
rpoC763951c.582G>C1.000
rpoC763960c.591T>G1.000
rpoC763969c.600C>T1.000
rpoC763978c.609C>T1.000
rpoC763987c.618C>T1.000
rpoC763991p.Ile208Leu1.000
rpoC763996c.627T>C1.000
rpoC764005c.636G>C1.000
rpoC764024c.655T>C1.000
rpoC764029p.Glu220Asp1.000
rpoC764032p.Asp221Glu1.000
rpoC764040p.Ser224Thr1.000
rpoC764044c.675T>C1.000
rpoC764059c.690G>T1.000
rpoC764071c.702G>C1.000
rpoC764083c.714A>G1.000
rpoC764084p.Asn239Val1.000
rpoC764089c.720C>G1.000
rpoC764098c.729A>G0.438
rpoC764101c.732C>G0.438
rpoC764102p.Val245Gln0.438
rpoC764134c.765C>G1.000
rpoC764153p.Gln262Lys1.000
rpoC764161c.792G>C1.000
rpoC764182p.Asp271Glu1.000
rpoC764188c.819A>G1.000
rpoC764195c.826T>A1.000
rpoC764203c.834G>C1.000
rpoC764206p.Asp279Glu1.000
rpoC764207p.Val280Thr1.000
rpoC764215c.846A>T1.000
rpoC764217p.Asn283Ser1.000
rpoC764221c.852C>T1.000
rpoC764227c.858G>C1.000
rpoC764239c.870T>G1.000
rpoC764254c.885G>T1.000
rpoC764257c.888G>C1.000
rpoC764263c.894G>T1.000
rpoC764266c.897T>C1.000
rpoC764272c.903G>C1.000
rpoC764278c.909A>G1.000
rpoC764293c.924G>C1.000
rpoC764297p.Met310Leu1.000
rpoC764344c.975C>T1.000
rpoC764353c.984G>T1.000
rpoC764365c.996C>T1.000
rpoC764371c.1002G>C1.000
rpoC764380c.1011G>C1.000
rpoC764387c.1018T>C1.000
rpoC764405c.1036A>C0.506
rpoC764431c.1062G>C1.000
rpoC764434c.1065A>G1.000
rpoC764435c.1066A>C1.000
rpoC764446c.1077T>C1.000
rpoC764449c.1080G>C1.000
rpoC764458c.1089G>C1.000
rpoC764461c.1092A>G1.000
rpoC764485c.1116G>C1.000
rpoC764491c.1122G>T1.000
rpoC764497c.1128A>G1.000
rpoC764500c.1131C>G1.000
rpoC764521c.1152T>C1.000
rpoC764527c.1158C>T1.000
rpoC764536c.1167G>T1.000
rpoC764539c.1170C>G1.000
rpoC764575c.1206T>G1.000
rpoC764605c.1236G>C1.000
rpoC764611c.1242G>T1.000
rpoC764623c.1254C>G1.000
rpoC764626c.1257C>T1.000
rpoC764632c.1263T>C1.000
rpoC764650c.1281G>T1.000
rpoC764701c.1332C>G1.000
rpoC764713c.1344G>T1.000
rpoC764716c.1347G>C1.000
rpoC764746c.1377G>T1.000
rpoC764752c.1383G>C1.000
rpoC764758c.1389C>G1.000
rpoC764764c.1395T>C1.000
rpoC764803c.1434C>T1.000
rpoC764809c.1440C>T1.000
rpoC764815c.1446A>G1.000
rpoC764824c.1455T>C1.000
rpoC764827c.1458G>C1.000
rpoC764851c.1482C>T1.000
rpoC764858c.1489T>C1.000
rpoC764869c.1500C>T1.000
rpoC764875c.1506C>T1.000
rpoC764878c.1509C>G1.000
rpoC764887c.1518G>C1.000
rpoC764888c.1519T>C1.000
rpoC764911c.1542A>G1.000
rpoC764912p.Met515Gln1.000
rpoC764932c.1563C>A0.980
rpoC764935c.1566T>C1.000
rpoC764948c.1579T>C1.000
rpoC764968c.1599T>C1.000
rpoC765007c.1638T>G1.000
rpoC765008c.1639T>C1.000
rpoC765011c.1642A>T1.000
rpoC765016c.1647C>A1.000
rpoC765022c.1653G>T1.000
rpoC765034c.1665T>C1.000
rpoC765040c.1671T>C1.000
rpoC765041c.1672T>C1.000
rpoC765047c.1678T>C1.000
rpoC765055c.1686C>G1.000
rpoC765073c.1704G>C1.000
rpoC765076c.1707A>G1.000
rpoC765079c.1710T>G1.000
rpoC765082c.1713G>T1.000
rpoC765083p.Arg572Lys1.000
rpoC765089c.1720T>C1.000
rpoC765103c.1734G>T1.000
rpoC765121c.1752G>T0.947
rpoC765129p.Tyr587Phe1.000
rpoC765259c.1890G>C1.000
rpoC765338p.Gln657Lys1.000
rpoC765352c.1983G>C1.000
rpoC765357p.Met663Thr1.000
rpoC765361c.1992C>G1.000
rpoC765383p.Met672Leu1.000
rpoC765400c.2031G>C1.000
rpoC765403c.2034G>C1.000
rpoC765404p.Leu679Lys1.000
rpoC765409c.2040T>C1.000
rpoC765412c.2043T>C1.000
rpoC765425p.Lys686Glu1.000
rpoC765445c.2076G>C1.000
rpoC765452p.Ala695Arg1.000
rpoC765466c.2097C>T1.000
rpoC765478c.2109T>C1.000
rpoC765480p.Tyr704Phe1.000
rpoC765496c.2127C>G1.000
rpoC765499c.2130C>G1.000
rpoC765529c.2160C>T1.000
rpoC765533p.Tyr722His1.000
rpoC765548c.2179A>T1.000
rpoC765553c.2184C>T1.000
rpoC765556c.2187G>C1.000
rpoC765562c.2193G>C1.000
rpoC765577c.2208G>T1.000
rpoC765586c.2217G>T1.000
rpoC765591p.Arg741Gln1.000
rpoC765596p.Lys743Gln0.905
rpoC765686p.Ala773Ser1.000
rpoC765694c.2325G>C1.000
rpoC765695p.Glu776Lys1.000
rpoC765700c.2331T>C1.000
rpoC765704p.Lys779Gln1.000
rpoC765709p.Glu780Asp1.000
rpoC765718p.Asp783Glu1.000
rpoC765724c.2355C>G1.000
rpoC765728p.Gln787Lys1.000
rpoC765734c.2365T>C1.000
rpoC765737p.Arg790Glu1.000
rpoC765743p.His792Tyr1.000
rpoC765751c.2382C>G1.000
rpoC765753p.Asp795Ala1.000
rpoC765772c.2403C>G1.000
rpoC765778c.2409C>G1.000
rpoC765779p.Asp804Lys1.000
rpoC765793c.2424C>G1.000
rpoC765796c.2427C>T1.000
rpoC765800p.Phe811Leu1.000
rpoC765811c.2442T>G1.000
rpoC765814c.2445A>C1.000
rpoC765817c.2448G>C1.000
rpoC765823c.2454C>A1.000
rpoC765826c.2457T>C1.000
rpoC765835c.2466C>T1.000
rpoC765871c.2502T>C1.000
rpoC765875p.Val836Ile1.000
rpoC765886c.2517C>G1.000
rpoC765904c.2535C>G1.000
rpoC765908c.2539C>T1.000
rpoC765934c.2565C>T1.000
rpoC765940c.2571A>T1.000
rpoC765946c.2577C>T1.000
rpoC765947c.2578T>C1.000
rpoC765952c.2583G>C1.000
rpoC765961c.2592G>T1.000
rpoC765962c.2593T>C1.000
rpoC765967c.2598C>T1.000
rpoC765979c.2610C>G0.458
rpoC765982c.2613C>T0.448
rpoC765994c.2625A>T1.000
rpoC766012c.2643C>G1.000
rpoC766021c.2652G>C1.000
rpoC766027c.2658G>T1.000
rpoC766034p.His889Thr1.000
rpoC766061p.Val898Ile1.000
rpoC766345c.2976T>C1.000
rpoC766348c.2979A>G1.000
rpoC766363c.2994G>C1.000
rpoC766381c.3012C>T1.000
rpoC766384c.3015A>G1.000
rpoC766390c.3021C>T1.000
rpoC766408c.3039C>T1.000
rpoC766594c.3225G>T1.000
rpoC766607p.Ile1080Leu0.394
rpoC766618c.3249G>T0.429
rpoC766624c.3255G>C1.000
rpoC766630c.3261G>C1.000
rpoC766634p.Phe1089Ile1.000
rpoC766638p.Lys1090Thr1.000
rpoC766645c.3276A>G1.000
rpoC766651c.3282T>C1.000
rpoC766658p.Arg1097Gly1.000
rpoC766666c.3297C>G1.000
rpoC766672c.3303T>C1.000
rpoC766675c.3306C>T1.000
rpoC766690c.3321G>C1.000
rpoC766694p.Gln1109Asp1.000
rpoC766714c.3345G>C1.000
rpoC766717c.3348C>G1.000
rpoC766720c.3351C>T1.000
rpoC766726c.3357T>C1.000
rpoC766738c.3369G>T1.000
rpoC766741c.3372G>C1.000
rpoC766765c.3396A>C1.000
rpoC766771c.3402G>C1.000
rpoC766774c.3405T>C1.000
rpoC766775p.Arg1136Lys1.000
rpoC766798c.3429C>G1.000
rpoC766804c.3435A>G1.000
rpoC766837c.3468G>C1.000
rpoC766843c.3474T>C1.000
rpoC766846c.3477C>G1.000
rpoC766931p.Ala1188Thr1.000
rpoC766942c.3573C>T1.000
rpoC766945c.3576A>C1.000
rpoC766948c.3579G>C1.000
rpoC766963c.3594T>C1.000
rpoC766981c.3612T>C1.000
rpoC766996c.3627C>T1.000
rpoC767002c.3633G>C1.000
rpoC767008c.3639G>A1.000
rpoC767020c.3651C>G1.000
rpoC767023c.3654C>T1.000
rpoC767098c.3729T>C1.000
rpoC767104c.3735C>G1.000
rpoC767105p.Asn1246Gln1.000
rpoC767119c.3750A>G1.000
rpoC767134c.3765C>T1.000
rpoC767138c.3769C>T1.000
rpoC767158c.3789T>C1.000
rpoC767162p.Asn1265Ala1.000
rpoC767167c.3798C>T1.000
rpoC767174p.Asn1269Asp1.000
rpoC767180p.Ala1271Gln1.000
rpoC767191c.3822C>G1.000
rpoC767197c.3828G>A1.000
rpoC767221c.3852C>G1.000
rpoC767230c.3861G>C1.000
rpoC767233c.3864T>C1.000
rpoC767263c.3894T>C1.000
rpoC767264p.Ala1299Gln1.000
rpoC767278c.3909T>C1.000
rpoC767281c.3912C>G1.000
rpoC767284c.3915C>G1.000
rpoC767296c.3927C>T1.000
rpsL781559c.-1G>C1.000
rpsL781572p.Gln5Asn0.958
rpsL781595c.36T>C1.000
rpsL781598c.39G>C1.000
rpsL781605p.Ile16Val1.000
rpsL781608p.Ser17Ala1.000
rpsL781628c.69T>C1.000
rpsL781631c.72G>C1.000
rpsL781649c.90T>C1.000
rpsL781655c.96T>C1.000
rpsL781658c.99A>G1.000
rpsL781682c.123T>C1.000
rpsL781709c.150G>C1.000
rpsL781715c.156T>C1.000
rpsL781728c.169T>C1.000
rpsL781742c.183C>T1.000
rpsL781751c.192G>C1.000
rpsL781760c.201T>C1.000
rpsL781772c.213C>T1.000
rpsL781808c.249C>T1.000
rpsL781814c.255C>T1.000
rpsL781817c.258G>T1.000
rpsL781829c.270G>C1.000
rpsL781832c.273T>C1.000
rpsL781838c.279G>C1.000
rpsL781841c.282C>T1.000
rpsL781859c.300T>G1.000
rpsL781865c.306G>C1.000
rpsL781868c.309T>C1.000
rpsL781871c.312G>C1.000
rpsL781892c.333A>G1.000
rpsL781898c.339A>C1.000
rpsL781901c.342C>T1.000
rpsL781907c.348T>C1.000
rpsL781916c.357T>C1.000
rpsL781929p.Gly124Ser0.979
rplC800844c.36T>C1.000
rplC800856c.48A>G1.000
rplC800862c.54C>T1.000
rplC800865c.57A>G1.000
rplC800867p.Ser20Asn1.000
rplC800873p.Arg22Lys1.000
rplC800877c.69A>C1.000
rplC800880c.72A>C1.000
rplC800889c.81C>G1.000
rplC800892c.84G>C1.000
rplC800895c.87C>G1.000
rplC800904c.96G>C1.000
rplC800916c.108A>G1.000
rplC800921p.Arg38Leu1.000
rplC800928c.120C>T1.000
rplC800931c.123G>C1.000
rplC800937c.129A>G1.000
rplC800946c.138T>C1.000
rplC800949c.141T>C1.000
rplC800964c.156G>C1.000
rplC800985c.177A>G1.000
rplC801003c.195G>C1.000
rplC801004p.Leu66Val1.000
rplC801009c.201A>C1.000
rplC801012c.204T>C1.000
rplC801019p.Thr71Ala1.000
rplC801027c.219C>G1.000
rplC801039c.231A>G1.000
rplC801171c.363A>G1.000
rplC801174c.366T>C1.000
rplC801195c.387G>T1.000
rplC801205p.Arg133Ala1.000
rplC801210c.402T>C1.000
rplC801220p.Ser138Ala1.000
rplC801237c.429G>A1.000
rplC801252c.444G>C1.000
rplC801264c.456C>T1.000
rplC801267c.459A>C1.000
rplC801276c.468G>C1.000
rplC801281p.Ala158Gly0.971
rplC801285c.477G>C1.000
rplC801307p.Ala167Ser1.000
rplC801312c.504G>C1.000
rplC801315c.507G>T1.000
rplC801324c.516T>C1.000
rplC801385c.577C>T0.667
rrs1471922r.77gt>g1.000
rrs1471925r.80t>c1.000
rrs1471931r.86ga>g1.000
rrs1471934r.89a>g1.000
rrs1471986r.141c>t1.000
rrs1472019r.174g>a1.000
rrs1472023r.178g>t1.000
rrs1472031r.186g>c1.000
rrs1472033r.188a>c1.000
rrs1472035r.190g>t1.000
rrs1472040r.195t>g1.000
rrs1472041r.196c>t1.000
rrs1472042r.197t>g1.000
rrs1472053r.208agc>a1.000
rrs1472061r.216a>t1.000
rrs1472075r.230a>g1.000
rrs1472106r.261g>a1.000
rrs1472108r.263c>t1.000
rrs1472150r.305t>a1.000
rrs1472251r.406g>a1.000
rrs1472286r.441c>a1.000
rrs1472287r.442c>t1.000
rrs1472289r.444t>g1.000
rrs1472290r.445c>g1.000
rrs1472297r.452ggtccgggttctct>g1.000
rrs1472312r.467g>gc1.000
rrs1472313r.468g>a1.000
rrs1472315r.470t>g1.000
rrs1472324r.479g>c1.000
rrs1472325r.480g>c1.000
rrs1472327r.482g>a1.000
rrs1472328r.483g>t0.963
rrs1472337r.492c>g1.000
rrs1472380r.535g>c1.000
rrs1472446r.601t>a1.000
rrs1472452r.607g>a1.000
rrs1472464r.619a>g1.000
rrs1472846r.1001c>a1.000
rrs1472847r.1002g>c1.000
rrs1472849r.1004c>g1.000
rrs1472850r.1005t>c1.000
rrs1472857r.1012a>g1.000
rrs1472858r.1013g>t1.000
rrs1472860r.1015c>g1.000
rrs1472861r.1016g>t1.000
rrs1472973r.1128a>t1.000
rrs1473104r.1259c>t0.990
rrs1473110r.1265t>g1.000
rrs1473111r.1266a>g1.000
rrs1473120r.1275c>ct0.981
rrs1473123r.1278a>c1.000
rrs1473276r.1431a>g1.000
rrs1473290r.1445c>t1.000
rrs1473291r.1446g>gt1.000
rrs1473301r.1456t>c1.000
rrl1473568c.-90G>T1.000
rrl1473569c.-89A>T1.000
rrl1473570c.-88A>T1.000
rrl1473571c.-87C>G1.000
rrl1473668r.11c>t1.000
rrl1473696r.39t>c1.000
rrl1473697r.40c>t1.000
rrl1473699r.42a>g1.000
rrl1473717r.60g>t1.000
rrl1473746r.89t>c1.000
rrl1473758r.101g>t1.000
rrl1473770r.113t>g1.000
rrl1473788r.131a>g1.000
rrl1473806r.149c>t1.000
rrl1473807r.150t>c1.000
rrl1473811r.154c>ct1.000
rrl1473823r.166t>c1.000
rrl1473829r.172g>t1.000
rrl1473830r.173t>g1.000
rrl1473831r.174g>t1.000
rrl1473832r.175c>a1.000
rrl1473876r.219g>a1.000
rrl1473884r.227c>ca0.915
rrl1473887r.230t>a1.000
rrl1473898r.241c>t1.000
rrl1473899r.242a>g1.000
rrl1473916r.259c>a1.000
rrl1473922r.265a>g1.000
rrl1473923r.266c>g1.000
rrl1473924r.267a>at1.000
rrl1473935r.278c>t1.000
rrl1473937r.280c>t1.000
rrl1473943r.286g>t1.000
rrl1473945r.288t>a1.000
rrl1473946r.289a>t1.000
rrl1473977r.320ggga>g1.000
rrl1474022r.365g>a1.000
rrl1474044r.387c>t1.000
rrl1474045r.388c>t1.000
rrl1474053r.396g>a1.000
rrl1474054r.397t>c1.000
rrl1474083r.426c>t1.000
rrl1474091r.434c>t1.000
rrl1474093r.436g>a1.000
rrl1474096r.439c>t1.000
rrl1474099r.442g>a1.000
rrl1474108r.451c>g1.000
rrl1474110r.453a>acggtg1.000
rrl1474135r.478g>a1.000
rrl1474140r.483c>t0.985
rrl1474151r.494c>t1.000
rrl1474174r.517a>g1.000
rrl1474181r.524c>t1.000
rrl1474183r.526t>c1.000
rrl1474185r.528g>a1.000
rrl1474186r.529a>g1.000
rrl1474249r.592g>t1.000
rrl1474266r.609t>c1.000
rrl1474269r.612c>t1.000
rrl1474289r.632c>t0.955
rrl1474292r.635t>g0.969
rrl1474308r.651g>t0.985
rrl1474310r.653t>g1.000
rrl1474362r.705a>g1.000
rrl1474414r.757c>t1.000
rrl1474417r.760acacgcgc>a1.000
rrl1474427r.770a>c1.000
rrl1474430r.773c>g1.000
rrl1474432r.775c>g1.000
rrl1474437r.780gaa>g1.000
rrl1474446r.789c>t1.000
rrl1474626r.969t>c0.985
rrl1474627r.970g>a1.000
rrl1474629r.972g>a1.000
rrl1474632r.975g>t1.000
rrl1474636r.979a>t1.000
rrl1474637r.980c>t1.000
rrl1474638r.981c>g1.000
rrl1474639r.982g>t1.000
rrl1474640r.983c>t1.000
rrl1474673r.1016t>c1.000
rrl1474676r.1019t>a1.000
rrl1474677r.1020a>g1.000
rrl1474710r.1053t>a1.000
rrl1474711r.1054g>c1.000
rrl1474712r.1055g>a1.000
rrl1474713r.1056t>a1.000
rrl1474717r.1060a>g0.978
rrl1474720r.1063c>t0.979
rrl1474753r.1096a>g1.000
rrl1474760r.1103a>g1.000
rrl1474794r.1137c>t1.000
rrl1474803r.1146g>a1.000
rrl1474812r.1155g>a1.000
rrl1474830r.1173a>g1.000
rrl1474932r.1275c>t1.000
rrl1474952r.1295acatcc>a1.000
rrl1475031r.1374g>t1.000
rrl1475061r.1404c>a1.000
rrl1475062r.1405a>t1.000
rrl1475120r.1463g>t0.988
rrl1475315r.1658a>t1.000
rrl1475353r.1696a>t1.000
rrl1475354r.1697a>g1.000
rrl1475355r.1698c>t1.000
rrl1475363r.1706c>t1.000
rrl1475369r.1712g>t1.000
rrl1475379r.1722g>a1.000
rrl1475380r.1723c>a1.000
rrl1475381r.1724g>c1.000
rrl1475382r.1725a>g1.000
rrl1475395r.1738t>c1.000
rrl1475396r.1739c>g1.000
rrl1475397r.1740g>t1.000
rrl1475398r.1741c>t1.000
rrl1475403r.1746t>a1.000
rrl1475404r.1747a>t1.000
rrl1475419r.1762c>t1.000
rrl1475429r.1772g>t1.000
rrl1475452r.1795c>a1.000
rrl1475479r.1822c>g1.000
rrl1475483r.1826c>t1.000
rrl1475505r.1848g>a1.000
rrl1475526r.1869c>a1.000
rrl1475531r.1874c>t1.000
rrl1475544r.1887a>t1.000
rrl1475545r.1888t>g1.000
rrl1475602r.1945g>c1.000
rrl1475603r.1946g>c1.000
rrl1475604r.1947a>c1.000
rrl1475612r.1955g>c1.000
rrl1475615r.1958c>g1.000
rrl1475616r.1959a>g1.000
rrl1475618r.1961c>t1.000
rrl1475626r.1969t>c1.000
rrl1475629r.1972g>c1.000
rrl1475637r.1980t>g1.000
rrl1475638r.1981c>g1.000
rrl1475639r.1982c>g1.000
rrl1475643r.1986c>g1.000
rrl1475647r.1990g>c1.000
rrl1475659r.2002g>a1.000
rrl1475753r.2096c>t0.987
rrl1475762r.2105g>t1.000
rrl1475763r.2106c>t1.000
rrl1475764r.2107a>c1.000
rrl1475765r.2108a>g1.000
rrl1475775r.2118g>a1.000
rrl1475988r.2331a>g1.000
rrl1475991r.2334t>c1.000
rrl1475995r.2338g>a1.000
rrl1476030r.2373a>g1.000
rrl1476032r.2375c>a1.000
rrl1476033r.2376t>g1.000
rrl1476035r.2378g>c1.000
rrl1476044r.2387t>g1.000
rrl1476046r.2389g>t1.000
rrl1476047r.2390g>t1.000
rrl1476049r.2392c>t1.000
rrl1476088r.2431a>c1.000
rrl1476099r.2442a>g1.000
rrl1476103r.2446c>g1.000
rrl1476105r.2448g>a1.000
rrl1476106r.2449a>t1.000
rrl1476110r.2453g>c1.000
rrl1476115r.2458t>c1.000
rrl1476131r.2474c>t1.000
rrl1476160r.2503t>c1.000
rrl1476214r.2557g>t1.000
rrl1476215r.2558c>t1.000
rrl1476224r.2567a>g1.000
rrl1476251r.2594t>g1.000
rrl1476256r.2599a>t1.000
rrl1476260r.2603a>g1.000
rrl1476281r.2624t>c1.000
rrl1476297r.2640c>t0.979
rrl1476299r.2642c>t1.000
rrl1476529r.2872a>g1.000
rrl1476540r.2883c>t1.000
rrl1476583r.2926g>a1.000
rrl1476584r.2927c>t1.000
rrl1476594r.2937c>t1.000
rrl1476597r.2940g>a1.000
rrl1476603r.2946g>a1.000
rrl1476628r.2971t>a1.000
rrl1476664r.3007t>c0.988
rrl1476665r.3008t>c1.000
rrl1476674r.3017t>c1.000
rrl1476679r.3022t>c1.000
rrl1476689r.3032a>t1.000
rrl1476690r.3033c>t1.000
rrl1476693r.3036g>a1.000
rrl1476695r.3038t>a1.000
rrl1476716r.3059a>c1.000
rrl1476723r.3066t>a1.000
rrl1476725r.3068c>t1.000
rrl1476726r.3069a>g1.000
rrl1476731r.3074g>a1.000
rrl1476732r.3075t>c0.986
rrl1476746r.3089t>c1.000
rrl1476747r.3090c>t1.000
rrl1476754r.3097g>a1.000
rrl1476759r.3102t>c1.000
rrl1476770r.3113t>c1.000
rrl1476771r.3114g>a1.000
fabG11673535c.96A>G0.667
fabG11673541c.102G>A0.643
fabG11673547c.108T>C1.000
fabG11673556c.117C>A1.000
fabG11673565c.126G>C1.000
fabG11673571c.132C>G1.000
fabG11673574c.135C>G1.000
fabG11673580c.141T>C1.000
fabG11673589c.150A>G1.000
fabG11673679c.240T>G1.000
fabG11673680p.Pro81Ser1.000
fabG11673703c.264C>T1.000
fabG11673724c.285A>G1.000
fabG11673730c.291C>G1.000
fabG11673745c.306G>A1.000
fabG11673748c.309A>G1.000
fabG11673749p.Lys104Arg1.000
fabG11673760p.Lys107Asn1.000
fabG11673778c.339C>G1.000
fabG11673784c.345G>C1.000
fabG11673787c.348G>C1.000
fabG11673799c.360T>A1.000
fabG11673802c.363A>G1.000
fabG11673808c.369A>G1.000
fabG11673865c.426C>G1.000
fabG11673870p.Ser144Met1.000
fabG11673877c.438C>G1.000
fabG11673886c.447C>T1.000
fabG11673895c.456C>T1.000
fabG11673901c.462A>G1.000
fabG11673905p.Ser156Ala1.000
fabG11673916c.477A>C1.000
fabG11673917p.Val160Leu1.000
fabG11673922c.483T>C1.000
fabG11673931c.492C>G1.000
fabG11673941p.Ala168Ser0.609
fabG11673955c.516G>C0.600
fabG11673961c.522A>C1.000
fabG11673962p.Asn175Gly1.000
fabG11673967c.528G>C1.000
fabG11673973c.534G>C1.000
fabG11673976c.537T>C1.000
fabG11674006p.Asp189Glu1.000
fabG11674024c.585T>C1.000
fabG11674037p.Gln200Ala1.000
fabG11674042c.603G>C1.000
fabG11674045c.606G>C1.000
fabG11674049p.Gln204Asp1.000
fabG11674054c.615T>C1.000
fabG11674060c.621A>C1.000
fabG11674079p.Pro214Ala1.000
fabG11674083p.Ala215Glu0.950
fabG11674096c.657G>C1.000
fabG11674098p.Val220Ala1.000
fabG11674102c.663C>G1.000
fabG11674114c.675T>A1.000
fabG11674123c.684T>C1.000
fabG11674132c.693T>C1.000
fabG11674136p.Ser233Ala1.000
fabG11674141c.702T>C1.000
fabG11674147c.708C>G0.310
fabG11674153c.714G>C0.333
inhA1674384c.183C>G1.000
inhA1674399c.198A>G1.000
inhA1674417c.216C>G1.000
inhA1674421c.220T>C1.000
inhA1674438c.237C>G0.174
inhA1674440p.Glu80Gly0.174
inhA1674444c.243G>C0.174
inhA1674450c.249G>C0.174
inhA1674452p.Ala84Glu0.174
inhA1674471c.270G>C1.000
inhA1674477c.276G>C1.000
inhA1674480c.279T>C1.000
inhA1674483c.282G>C1.000
inhA1674486c.285T>C1.000
inhA1674489c.288G>C1.000
inhA1674504c.303C>G1.000
inhA1674507c.306G>C1.000
inhA1674513c.312C>G1.000
inhA1674514p.Ile105Val1.000
inhA1674522c.321G>C1.000
inhA1674534c.333G>C1.000
inhA1674537c.336C>G1.000
inhA1674543c.342G>C1.000
inhA1674549c.348G>C1.000
inhA1674550p.Ser117Ala1.000
inhA1674573c.372G>C1.000
inhA1674576c.375T>C1.000
inhA1674579c.378G>C1.000
inhA1674582c.381T>C1.000
inhA1674585c.384T>C1.000
inhA1674589p.Met130Leu1.000
inhA1674600c.399G>C1.000
inhA1674601p.Leu134Thr1.000
inhA1674651c.450C>T1.000
inhA1674656p.Ser152Thr1.000
inhA1674660c.459G>C1.000
inhA1674663c.462G>C1.000
inhA1674672c.471C>A1.000
inhA1674690c.489C>G1.000
inhA1674702c.501G>T1.000
inhA1674703c.502T>C1.000
inhA1674718c.517A>C1.000
inhA1674729c.528G>T1.000
inhA1674742p.Lys181Ala1.000
inhA1674745p.Tyr182Ala1.000
inhA1674753c.552G>C1.000
inhA1674774c.573A>C1.000
inhA1674777c.576C>G1.000
inhA1674780c.579T>G1.000
inhA1674789c.588G>T1.000
inhA1674792c.591G>C1.000
inhA1674795c.594G>C1.000
inhA1674801c.600T>C1.000
inhA1674804c.603G>C1.000
inhA1674876c.675C>T1.000
inhA1674879c.678T>G1.000
inhA1674904p.Ala235Pro1.000
inhA1674924c.723G>T1.000
inhA1674930c.729C>T1.000
inhA1674934c.733C>T1.000
inhA1674942c.741T>C1.000
inhA1674949p.Leu250Met1.000
inhA1674954c.753G>C1.000
inhA1674957c.756G>C1.000
inhA1674963c.762G>A1.000
inhA1674966c.765T>C1.000
inhA1674967p.Asp256Thr1.000
rpsA1833539c.-3A>C1.000
rpsA1833541c.-1T>C1.000
rpsA1833547c.6G>A1.000
rpsA1833554p.Thr5Ser1.000
rpsA1833589c.48A>C1.000
rpsA1833595c.54T>G1.000
rpsA1833596p.Ser19Ala1.000
rpsA1833616c.75A>C1.000
rpsA1833619c.78A>C1.000
rpsA1833628c.87G>C1.000
rpsA1833634c.93G>A1.000
rpsA1833661c.120A>G1.000
rpsA1833664c.123C>A0.971
rpsA1833676c.135A>G1.000
rpsA1833679c.138G>T1.000
rpsA1833685c.144G>T1.000
rpsA1833694c.153G>C1.000
rpsA1833697c.156C>G1.000
rpsA1833703c.162C>T1.000
rpsA1833724c.183C>T1.000
rpsA1833727c.186G>C1.000
rpsA1833730c.189C>T1.000
rpsA1833733c.192C>T1.000
rpsA1833734p.Ala65Ser1.000
rpsA1833745c.204G>C1.000
rpsA1833760c.219C>T0.500
rpsA1833787c.246C>G1.000
rpsA1833790c.249T>C1.000
rpsA1833793c.252C>T1.000
rpsA1833802c.261A>G1.000
rpsA1833811c.270G>T1.000
rpsA1833829c.288A>G1.000
rpsA1833832c.291G>A1.000
rpsA1833838c.297G>C1.000
rpsA1833841c.300C>G1.000
rpsA1833847c.306C>G1.000
rpsA1833856c.315A>G1.000
rpsA1833862c.321G>T1.000
rpsA1833894p.Ala118Glu1.000
rpsA1833904c.363G>A1.000
rpsA1833928c.387G>C1.000
rpsA1833949c.408T>C1.000
rpsA1833970c.429G>T1.000
rpsA1833976c.435C>T1.000
rpsA1833979c.438T>C1.000
rpsA1833991c.450C>A1.000
rpsA1834000c.459G>C1.000
rpsA1834009c.468C>T1.000
rpsA1834012c.471G>T1.000
rpsA1834015c.474G>C1.000
rpsA1834021c.480C>T1.000
rpsA1834030c.489C>G1.000
rpsA1834078c.537C>T1.000
rpsA1834097c.556T>A1.000
rpsA1834102c.561T>C1.000
rpsA1834150c.609G>C1.000
rpsA1834153c.612T>C1.000
rpsA1834154p.Asn205Gln1.000
rpsA1834157c.616T>C1.000
rpsA1834162c.621A>G1.000
rpsA1834165c.624A>G1.000
rpsA1834169p.Thr210Ala1.000
rpsA1834177c.636A>C1.000
rpsA1834189c.648G>C1.000
rpsA1834213c.672G>C1.000
rpsA1834234c.693G>C1.000
rpsA1834240c.699T>C1.000
rpsA1834246c.705G>C1.000
rpsA1834249c.708T>C1.000
rpsA1834252c.711C>G1.000
rpsA1834261c.720A>G1.000
rpsA1834264c.723G>C1.000
rpsA1834279c.738C>T1.000
rpsA1834297c.756C>T1.000
rpsA1834303c.762T>G1.000
rpsA1834306c.765T>C1.000
rpsA1834345c.804C>T1.000
rpsA1834348c.807T>C1.000
rpsA1834361c.820T>C1.000
rpsA1834366c.825A>G1.000
rpsA1834396c.855G>C1.000
rpsA1834411c.870T>C1.000
rpsA1834423c.882G>T1.000
rpsA1834451c.910T>C1.000
rpsA1834456c.915T>G1.000
rpsA1834468c.927A>G1.000
rpsA1834489c.948T>C1.000
rpsA1834498c.957C>T1.000
rpsA1834513c.972C>G1.000
rpsA1834520p.Ala327Ser1.000
rpsA1834528c.987T>C1.000
rpsA1834540c.999G>C1.000
rpsA1834543c.1002C>G1.000
rpsA1834546c.1005T>C1.000
rpsA1834606c.1065C>T1.000
rpsA1834609c.1068T>C1.000
rpsA1834619c.1078T>C1.000
rpsA1834622c.1081T>A1.000
rpsA1834633c.1092A>G1.000
rpsA1834639c.1098T>C1.000
rpsA1834666c.1125G>C1.000
rpsA1834667p.Ala376Ser1.000
rpsA1834690c.1149T>C1.000
rpsA1834732c.1191T>C1.000
rpsA1834738c.1197A>G1.000
rpsA1834753c.1212T>C1.000
rpsA1834756c.1215G>A1.000
rpsA1834759c.1218A>C1.000
rpsA1834765p.Glu408Asp1.000
rpsA1834774c.1233C>G1.000
rpsA1834776p.Ala412Glu1.000
rpsA1834780c.1239A>G1.000
rpsA1834786c.1245A>G1.000
rpsA1834789c.1248T>C1.000
rpsA1834792c.1251G>C1.000
rpsA1834829p.Ala430Thr1.000
rpsA1834852c.1311C>G0.414
tlyA1918629c.690G>C1.000
tlyA1918632c.693G>C1.000
tlyA1918635c.696C>A1.000
katG2155080c.1032C>G1.000
katG2155266c.846A>G1.000
katG2155270p.Ala281Gly1.000
katG2155284c.828A>G1.000
katG2155287c.825G>T1.000
katG2155298p.Phe272Leu1.000
katG2155299c.813A>T1.000
katG2155305c.807A>C1.000
katG2155323c.789C>G0.520
katG2155661p.Val151Leu1.000
katG2155668c.444C>G1.000
katG2155674c.438C>G1.000
katG2155680c.432C>T1.000
katG2155691c.421A>G1.000
katG2155696p.Ala139Val1.000
katG2155716c.396A>C1.000
katG2155722c.390C>G1.000
katG2155728c.384C>G1.000
katG2155742p.Gly124Arg1.000
katG2155747p.Ala122Gly1.000
katG2155752c.360G>A1.000
katG2155766p.His116Val0.333
katG2155769p.Ile115Val0.667
katG2155770c.342G>C0.667
katG2155779c.333G>A0.333
katG2155782c.330G>T0.667
katG2155785c.327A>G0.333
katG2155796p.Ala106Cys0.350
katG2155800c.312C>G0.650
katG2155805p.Ile103Val0.650
katG2155806c.306A>G1.000
katG2155815c.297C>G1.000
katG2155823p.His97Ser0.350
katG2155824c.288G>C0.371
katG2155828p.Tyr95Phe0.371
katG2155836c.276G>C0.371
pncA2289179c.63T>G1.000
pncA2289191c.51G>C1.000
kasA2518219c.105T>C1.000
kasA2518222c.108G>C1.000
kasA2518223c.109T>C1.000
kasA2518231c.117C>A1.000
kasA2518234c.120G>A1.000
kasA2518534c.420G>C1.000
kasA2518543c.429G>A1.000
kasA2518606c.492G>C1.000
kasA2518609p.Met165Ile1.000
kasA2518612c.498C>T1.000
kasA2518624c.510C>G1.000
kasA2518636c.522C>A1.000
kasA2518639c.525G>T1.000
kasA2518642c.528A>G1.000
kasA2518645c.531G>C1.000
kasA2518656p.Ala181Gly1.000
kasA2518663c.549T>C1.000
kasA2518672c.558G>C1.000
kasA2518678c.564C>T1.000
kasA2518684c.570C>G1.000
kasA2518688p.Val192Phe1.000
kasA2518697p.Cys195Val1.000
kasA2518708c.594C>G1.000
kasA2518714c.600A>C1.000
kasA2518715p.Pro201Gly1.000
kasA2518726c.612G>A1.000
kasA2518732c.618C>G1.000
kasA2518747c.633C>G1.000
kasA2518756c.642G>C1.000
kasA2518780p.Glu222Asp1.000
kasA2518783c.669T>C1.000
kasA2518785p.Glu224Ala1.000
kasA2518787p.Arg225Gly1.000
kasA2518792c.678C>G1.000
kasA2518795c.681C>T1.000
kasA2518813c.699C>T1.000
kasA2518816c.702C>T1.000
kasA2518825c.711T>C1.000
kasA2518843c.729T>C1.000
kasA2518847p.Leu245Met1.000
kasA2518853p.Leu247Ile1.000
kasA2518864c.750G>C1.000
kasA2518877p.Lys255Leu1.000
kasA2518898c.784T>C1.000
kasA2518903c.789C>T1.000
kasA2518906c.792A>G1.000
kasA2518907c.793T>C1.000
kasA2518910p.Leu266Met0.933
kasA2519183c.1069C>T0.409
kasA2519193p.Leu360His0.625
kasA2519195p.Thr361Ala1.000
kasA2519198c.1084C>T0.273
kasA2519203c.1089C>T0.273
kasA2519209c.1095C>G0.273
kasA2519212c.1098C>G0.273
kasA2519218c.1104G>T0.273
kasA2519323c.1209G>A1.000
kasA2519344c.1230G>C1.000
kasA2519347c.1233T>G1.000
folC2746854p.Ser249Ala1.000
folC2746957c.642C>G1.000
folC2746960c.639G>C1.000
folC2746967p.Gly211Glu1.000
folC2746977p.Asp208Thr1.000
folC2746979p.Ala207Asp1.000
folC2746987c.612A>G1.000
folC2746995p.Val202Thr1.000
folC2746999c.600A>G1.000
folC2747002c.597A>G1.000
folC2747007p.Ser198Gly1.000
folC2747023c.576G>C1.000
folC2747029c.570C>G1.000
folC2747032c.567T>G1.000
folC2747040p.Ile187Val1.000
folC2747041c.558C>G1.000
folC2747062c.537T>G1.000
folC2747065c.534G>T1.000
folC2747071c.528G>C1.000
folC2747074c.525C>G1.000
folC2747082p.Val173Ile1.000
folC2747085p.Val172Ile1.000
folC2747087p.Ala171Gly1.000
folC2747089c.510C>G1.000
folC2747097p.Val168Ile1.000
folC2747102p.Ala166Val1.000
folC2747107c.492C>G1.000
folC2747110c.489A>G1.000
folC2747116c.483C>G1.000
folC2747136c.463G>C1.000
folC2747137c.462C>G1.000
thyX3067319c.627C>G1.000
thyX3067325c.621T>C1.000
thyX3067331c.615G>A1.000
thyX3067334c.612G>C1.000
thyX3067340c.606C>T1.000
thyX3067346c.600G>C1.000
thyX3067349c.597C>G1.000
thyX3067355c.591T>G1.000
thyX3067376c.570C>G1.000
thyX3067415c.531G>A1.000
thyX3067423c.523G>A1.000
thyX3067424c.522C>T1.000
thyX3067427c.519C>G1.000
thyX3067436c.510G>C1.000
thyX3067439c.507T>C1.000
thyX3067442c.504G>C1.000
thyX3067457c.489G>A1.000
thyX3067465p.Ile161Val1.000
thyX3067466c.480C>G1.000
thyX3067475c.471T>C1.000
thyX3067619c.327T>G1.000
thyX3067625c.321G>A1.000
thyX3067631c.315G>C1.000
thyX3067640c.306C>G1.000
thyX3067652c.294A>G1.000
thyX3067655c.291C>T1.000
thyX3067661c.285G>C1.000
thyX3067669c.277G>A1.000
thyX3067673c.273G>A1.000
thyX3067681p.Cys89Ala1.000
thyX3067685c.261T>C1.000
thyX3067688c.258C>G1.000
thyX3067709c.237C>G1.000
thyX3067765p.Leu61Ile1.000
thyX3067771p.Gly59Ser0.952
thyX3067773p.Ala58Glu1.000
thyX3067781c.165G>C1.000
thyX3067788p.Lys53Arg1.000
thyX3067808c.138G>A1.000
thyX3067814c.132A>G1.000
thyX3067817c.129G>A1.000
thyX3067820c.126G>C1.000
thyX3067825c.121G>T1.000
thyX3067840p.Val36Thr1.000
thyX3067841c.105C>G1.000
thyX3067847c.99G>A1.000
thyX3067853c.93G>A1.000
thyX3067862c.84G>A1.000
thyX3067869p.Thr26Ser1.000
thyX3067874c.72G>C1.000
thyA3073836c.636G>A1.000
thyA3073839c.633A>G1.000
thyA3073845c.627G>A1.000
thyA3073860c.612G>A1.000
thyA3073863c.609A>G1.000
thyA3073874p.Ile200Val1.000
thyA3073902c.570G>C1.000
thyA3073922c.550G>C1.000
thyA3073925c.547A>G1.000
thyA3073926c.546C>G1.000
thyA3073929c.543A>G1.000
thyA3073959c.513A>G1.000
thyA3073962c.510C>G1.000
thyA3073971c.501G>A1.000
thyA3073977c.495T>C1.000
thyA3073983c.489G>C1.000
thyA3073989c.483A>G1.000
thyA3073994c.478C>G1.000
thyA3073997c.475G>A1.000
thyA3074000p.Arg158Lys1.000
thyA3074013c.459G>A1.000
ald3087251c.432T>C1.000
ald3087255p.Ala146Ser1.000
ald3087272c.453A>C1.000
ald3087275c.456C>A1.000
ald3087278c.459A>G1.000
ald3087281c.462G>C1.000
ald3087284c.465C>T1.000
ald3087305c.486G>C1.000
ald3087319p.Glu167Ala1.000
ald3087359c.540C>T1.000
ald3087368c.549A>T1.000
ald3087699p.Leu294Val1.000
ald3087704c.885T>C1.000
ald3087716c.897G>C1.000
ald3087727p.Ala303Gly1.000
ald3087751p.Tyr311Phe1.000
fbiA3640863c.321C>G1.000
fbiA3640884c.342G>C1.000
fbiA3640901p.Gln120Arg1.000
fbiA3641073c.531T>C1.000
fbiA3641085c.543G>C1.000
fbiA3641086p.Thr182Ser1.000
fbiA3641100c.558T>G1.000
fbiA3641103c.561T>C1.000
alr3840230c.1191A>C1.000
alr3840236c.1185T>C1.000
alr3840262p.His387Asn1.000
alr3840274p.Val383Leu1.000
alr3840278p.Asp381Glu1.000
alr3840287c.1134G>A1.000
alr3840371c.1050C>G1.000
alr3840377c.1044G>T1.000
alr3840382p.Met347Val1.000
alr3840404c.1017C>T1.000
alr3840407c.1014C>G1.000
alr3840411p.Gly337Ala1.000
alr3840413c.1008G>C1.000
alr3840418p.Cys335Arg1.000
alr3840419c.1002T>G1.000
alr3840445p.Leu326Ile1.000
alr3840454p.Gly323Ser0.607
alr3840457c.964G>A0.600
alr3840461c.960C>G0.593
alr3840469p.Val318Ile1.000
panD4044230c.53 54insAG1.000
panD4044258c.24C>G1.000
panD4044261c.21C>T1.000
embC4240106c.244T>C1.000
embC4240110p.Asn83Thr1.000
embC4240120c.258C>G1.000
embC4240141c.279A>G1.000
embC4240717c.855T>C1.000
embC4240768c.906G>A1.000
embC4240780c.918T>C0.926
embC4240783c.921G>C1.000
embC4240786c.924C>T0.925
embC4240789c.927T>C1.000
embC4240819c.957A>C1.000
embC4240828c.966G>A1.000
embC4240831c.969T>G1.000
embC4241017c.1155T>C1.000
embC4241023c.1161T>G1.000
embC4241024p.Val388Phe1.000
embC4241038c.1176G>C1.000
embC4241039p.Asp393Asn1.000
embC4241047c.1185C>G1.000
embC4241050c.1188T>G1.000
embC4241053c.1191G>C1.000
embC4241059c.1197G>A1.000
embC4241074c.1212G>C1.000
embC4241095c.1233C>T1.000
embC4241104c.1242G>A0.900
embC4241107c.1245G>C0.900
embC4241109p.Ala416Gly1.000
embC4241416c.1554C>G1.000
embC4241420p.Glu520Ser1.000
embC4241560c.1698C>G1.000
embC4241584c.1722T>C1.000
embC4241587c.1725C>G1.000
embC4241593c.1731C>G1.000
embC4241611c.1749G>C0.692
embC4241614c.1752A>C1.000
embC4241626c.1764T>C1.000
embC4241635c.1773G>C1.000
embC4241644c.1782G>C1.000
embC4241647c.1785G>A1.000
embC4241648c.1786T>C1.000
embC4241656c.1794G>A1.000
embC4241659c.1797G>C1.000
embC4241665c.1803G>T1.000
embC4241668c.1806G>C1.000
embC4241671c.1809T>G1.000
embC4241691p.Gly610Ala1.000
embC4241695c.1833T>G1.000
embC4241750p.Leu630Met1.000
embC4241756c.1894C>T1.000
embC4241767c.1905C>G1.000
embC4241769p.Ser636Thr1.000
embC4241809c.1947A>C1.000
embC4242826c.2964G>C1.000
embC4242832c.2970A>G1.000
embC4242838c.2976C>G1.000
embC4242841c.2979C>T1.000
embC4242844c.2982A>G1.000
embC4242847c.2985C>G1.000
embC4242859c.2997C>T1.000
embC4242862c.3000A>G1.000
embC4242872p.Asp1004Thr1.000
embC4242878p.Thr1006Val1.000
embC4242907c.3045G>C1.000
embC4242919c.3057A>G1.000
embC4242928c.3066A>G1.000
embA4244340p.Ser370Ala1.000
embA4244345c.1113C>G1.000
embA4244349p.Leu373Met1.000
embA4244372c.1140T>C1.000
embA4244378c.1146G>A1.000
embA4244381c.1149G>C1.000
embA4244645c.1413T>C1.000
embA4244648c.1416G>C1.000
embA4244665p.Thr478Ser1.000
embA4244669c.1437G>C1.000
embA4244681c.1449A>C1.000
embA4244684c.1452C>G1.000
embA4244695p.Lys488Thr1.000
embA4244712p.Ala494Ser1.000
embA4244726p.Asp498Glu1.000
embA4244747c.1515T>G1.000
embA4244878p.Ala549Val1.000
embA4244885c.1653A>G1.000
embA4244897c.1665T>C1.000
embA4244900c.1668G>C1.000
embA4244903c.1671G>C1.000
embA4244904p.Val558Ile1.000
embA4244909c.1677C>T1.000
embA4244920563LT>563LH0.958
embA4244933c.1701A>C1.000
embA4244939c.1707G>A1.000
embA4244957c.1725C>T1.000
embA4244960c.1728A>C1.000
embA4244964p.Ala578Thr1.000
embA4245042p.Thr604Ala1.000
embA4245053c.1821G>C1.000
embA4245060c.1828T>C1.000
embA4245071c.1839G>C1.000
embA4245083c.1851A>C1.000
embA4245092c.1860C>G1.000
embA4245094p.Ile621Thr1.000
embA4245101c.1869G>C1.000
embA4245125c.1893G>C1.000
embA4245431c.2199T>C1.000
embA4245454p.Ala741Val1.000
embA4245459p.Pro743Ala1.000
embA4245465p.Pro745Thr1.000
embA4245762p.Gly844Lys1.000
embA4245772p.Asn847Thr1.000
embA4245774p.Leu848Val1.000
embA4245784p.Thr851Lys1.000
embA4245807c.2575T>C1.000
embA4245815c.2583C>G1.000
embA4245818c.2586C>G1.000
embA4245820p.Ser863Thr1.000
embA4245822p.Pro864Ala1.000
embA4246164p.Leu978Met0.550
embA4246184c.2952A>C1.000
embA4246187c.2955C>G1.000
embA4246190c.2958C>T1.000
embA4246199c.2967C>T1.000
embA4246202c.2970G>A1.000
embA4246205c.2973A>C1.000
embA4246211c.2979T>C1.000
embA4246217c.2985G>A1.000
embA4246220c.2988T>C1.000
embA4246227p.Ile999Val1.000
embA4246238c.3006T>G1.000
embA4246242p.Gln1004Glu1.000
embA4246250c.3018G>C1.000
embB4246869p.Ser119Asn1.000
embB4246874p.Gln121Lys1.000
embB4246882c.369G>C0.609
embB4246886p.Val125Ile0.609
embB4247389c.876C>G1.000
embB4247398c.885G>C1.000
embB4247401c.888T>C1.000
embB4247407c.894G>C1.000
embB4247426p.Gly305Gln1.000
embB4247434c.921C>G1.000
embB4247437c.924A>C1.000
embB4247440c.927C>G1.000
embB4247449c.936C>T0.974
embB4247464c.951C>G0.974
embB4247470c.957T>C1.000
embB4247491c.978G>C1.000
embB4247497c.984T>C0.974
embB4247511p.Tyr333Phe0.971
embB4247527c.1014G>C1.000
embB4247536c.1023C>G1.000
embB4247554c.1041T>C0.950
embB4247555p.Leu348Ile0.950
embB4247566c.1053C>A1.000
embB4247572c.1059A>C1.000
embB4247590c.1077A>G1.000
embB4247638c.1125G>C1.000
embB4247716c.1203C>A1.000
embB4247968c.1455C>T1.000
embB4247977c.1464C>G1.000
embB4247992c.1479G>C1.000
embB4248052c.1539G>C1.000
embB4248063p.Ala517Glu1.000
embB4248070c.1557T>C1.000
embB4248085c.1572T>C1.000
embB4248097c.1584C>G1.000
embB4248112c.1599C>G1.000
embB4248118c.1605T>C1.000
embB4248130c.1617G>C1.000
embB4248133c.1620C>G1.000
embB4248142c.1629T>C1.000
embB4248143p.Leu544Ile1.000
embB4248151c.1638C>A1.000
embB4248157c.1644A>G1.000
embB4248158p.Cys549Ser1.000
embB4248167p.Thr552Ala1.000
embB4248170p.Ala553Ser1.000
embB4248173p.Val554Leu1.000
embB4248199c.1686A>G1.000
embB4248200p.Ile563Val1.000
embB4248206p.Ser565Gly1.000
embB4248220c.1707A>G1.000
embB4248225p.Ala571Val1.000
embB4248233c.1720C>T1.000
embB4248242p.Val577Ile0.955
embB4248252p.Gly580Ala1.000
embB4248264p.Phe584Cys0.953
embB4248277c.1764G>C1.000
embB4248290p.Val593Ile0.414
embB4248298c.1785C>T0.414
embB4248304c.1791G>C0.571
embB4248318p.Val602Ala0.450
embB4248322c.1809G>T0.433
embB4248432p.Trp640Phe1.000
embB4248437p.Thr642Ser0.422
embB4248448c.1935C>G0.409
embB4248450p.Trp646Phe0.409
embB4248457c.1944T>C1.000
embB4248460c.1947C>G0.549
embB4248472c.1959T>C0.536
embB4249686p.Ala1058Gly1.000
embB4249693c.3180T>C1.000
ethA4326844c.630G>A1.000
ethA4326850c.624T>C0.655
ethA4326868c.606G>C0.327
ethA4327396c.78A>G1.000
ethA4327405c.69C>G1.000
ethA4327419p.Ala19Thr1.000
gid4408253c.-51A>G1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
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