TB Profiler
This tool processes raw sequence data to infer strain type and identify known drug resistance markers.
A stand alone version of this tool is now available and can now be run on linux or mac. Installation instructions can be found on GitHub and on the bioconda page.



This tool is for Research Use Only. Data and information provided through use of this tool are not intended for medical purpose or objective and should not be used for clinical diagnosis, patient management, or human clinical trials.
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Single nucleotide polymorphisms (SNPs) in coding regions are annotated using the reference amino acid, codon number and alternative amino acid (e.g. Ser315Thr in katG). SNPs in non-coding regions (i.e. RNA genes and intergenic regions) are annotated using the reference nucleotide, gene coordinate and alternative nucleotide (e.g. A1401G in rrs or C-37A in eis promoter). Indels are annotated using the reference VCF allele, gene coordinate and alternative VCF allele (e.g. T902TA insertion in katG).
Name: 5d8085ff392dc
Sample: 5d8085ff392dc

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Summary
ID: 5d8085ff392dc
Date: Tue Sep 17 08:42:16 2019
Strain: lineage1;lineage4.3;lineage2.2;lineage4.6.1;lineage4.1.1;lineage2.2.1;lineage4.1.1.1
Drug-resistance: MDR

Drug1ResistanceSupporting Mutations (frequency)
IsoniazidRkatG p.Ile335Thr (0.13), katG p.Ser315Thr (0.90)
RifampicinRrpoB p.Ser450Leu (0.38)
EthambutolRembB p.His312Arg (0.49), embB p.Leu359Ile (0.24), embB p.Ala388Gly (0.38), embB p.Asn399Asp (0.47), embB p.Ala659Thr (0.60)
Pyrazinamide
StreptomycinRrpsL p.Lys43Arg (0.32), rrs r.462c>t (0.62)
Ethionamide
Fluoroquinolones
Amikacin
Capreomycin
Kanamycin

Lineage2FamilyMain SpoligotypeRDS
lineage1Indo-OceanicEAIRD239
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage4.1.1.1Euro-American (X-type)X2RD183

Mutations in candidate genes:
GeneChromosome PositionMutationEstimated fraction
gyrB6082c.843G>A0.367
gyrB6086p.Thr283Pro0.360
gyrB6091c.852G>C0.462
gyrB6100c.861G>C0.500
gyrB6103c.864G>A0.103
gyrB6115c.876A>G0.540
gyrB6123p.Ala295Gly0.492
gyrB6127c.888G>C0.492
gyrB6130c.891T>C0.537
gyrB6136c.897G>A0.384
gyrB6139c.900G>C0.395
gyrB6145c.906C>T0.181
gyrB6196c.957C>T0.600
gyrB6208c.969G>C0.140
gyrB6214c.975G>C0.138
gyrB6238c.999G>A0.565
gyrB6242p.Arg335Lys0.619
gyrB6250c.1011A>G0.671
gyrB6256c.1017G>A0.616
gyrB6268c.1029C>G0.628
gyrB6280c.1041T>C0.704
gyrB6286c.1047T>C0.716
gyrB6289c.1050C>T0.636
gyrB6292c.1053G>C0.618
gyrB6307c.1068T>G0.710
gyrB6319c.1080G>C0.689
gyrB6362c.1123T>C0.691
gyrB6376c.1137G>A0.611
gyrB6379c.1140C>G0.615
gyrB6382c.1143A>G0.635
gyrB6388c.1149T>C0.633
gyrB6403c.1164T>C0.622
gyrB6415c.1176G>C0.568
gyrB6427c.1188T>C0.500
gyrB6430c.1191A>G0.467
gyrB6440p.Thr401Ala0.179
gyrB6565c.1326G>C0.158
gyrB6571c.1332T>C0.139
gyrB6577c.1338T>C0.216
gyrB6580c.1341C>G0.243
gyrB6598c.1359C>G0.317
gyrB6610c.1371C>G0.333
gyrB6613c.1374A>G0.310
gyrB6616c.1377A>G0.317
gyrB6622c.1383C>T0.317
gyrB6634c.1395T>C0.404
gyrB6637c.1398T>G0.404
gyrB6640c.1401A>G0.404
gyrB6643c.1404A>G0.396
gyrB6649c.1410T>C0.444
gyrB6655c.1416T>C0.463
gyrB6670c.1431G>C0.475
gyrB6673c.1434A>C0.500
gyrB6676c.1437T>G0.500
gyrB6700c.1461T>C0.524
gyrB6703c.1464G>C0.516
gyrB6709c.1470A>G0.492
gyrB6712c.1473G>C0.522
gyrB6728c.1489C>T0.451
gyrB6742c.1503A>G0.461
gyrB6745c.1506T>G0.539
gyrB6751c.1512G>C0.609
gyrB6760c.1521G>C0.628
gyrB6763c.1524G>C0.495
gyrB6775c.1536G>C0.645
gyrB6793c.1554T>C0.614
gyrB6797p.Gly520Thr0.457
gyrB6811c.1572C>T0.467
gyrB6817c.1578G>A0.154
gyrB6841c.1602T>C0.529
gyrB6844c.1605T>C0.450
gyrB6853c.1614A>G0.456
gyrB6856c.1617T>C0.455
gyrB6859c.1620T>C0.456
gyrB6868c.1629G>C0.377
gyrB6877c.1638G>T0.162
gyrB6878c.1639T>C0.158
gyrB6881c.1642T>C0.154
gyrB6889c.1650G>T0.256
gyrB6901c.1662G>C0.289
gyrB6904c.1665C>G0.283
gyrB6910c.1671G>A0.340
gyrB6916c.1677G>C0.260
gyrB6919c.1680T>C0.347
gyrB6925c.1686T>C0.353
gyrB6931c.1692A>G0.400
gyrB6949c.1710A>G0.431
gyrB6952c.1713C>G0.431
gyrB6967c.1728T>C0.549
gyrB6973c.1734G>C0.518
gyrB6982c.1743A>C0.547
gyrB6985c.1746C>T0.464
gyrB7006c.1767T>C0.490
gyrB7007c.1768C>T0.480
gyrB7010c.1771C>T0.471
gyrB7015c.1776G>A0.471
gyrB7023p.Leu595Gln0.444
gyrB7033c.1794G>C0.471
gyrB7051p.Glu604Asp0.391
gyrB7066c.1827G>C0.444
gyrB7075c.1836T>C0.318
gyrB7078c.1839A>C0.326
gyrB7084c.1845A>G0.319
gyrB7090c.1851C>T0.340
gyrB7093c.1854T>G0.367
gyrB7099c.1860G>A0.373
gyrB7108c.1869G>A0.423
gyrB7114c.1875C>A0.458
gyrB7124p.Ser629Thr0.383
gyrB7129c.1890T>C0.409
gyrB7132c.1893T>G0.480
gyrB7141c.1902T>C0.518
gyrB7147c.1908G>C0.536
gyrB7165c.1926C>G0.515
gyrB7178c.1939T>C0.612
gyrB7186c.1947C>G0.578
gyrB7210c.1971C>T0.523
gyrB7216c.1977G>C0.565
gyrB7234c.1995C>T0.549
gyrB7246c.2007T>C0.543
gyrB7252c.2013G>C0.543
gyrB7256c.2017C>T0.442
gyrA7313c.12G>C0.130
gyrA7317c.16T>C0.136
gyrA7334c.33G>C0.444
gyrA7335p.Leu12Val0.444
gyrA7347p.Glu16Gln0.444
gyrA7355c.54T>C0.457
gyrA7361c.60C>T0.543
gyrA7362p.Glu21Gln1.000
gyrA7391c.90C>T0.542
gyrA7394c.93T>C0.533
gyrA7406c.105G>C0.413
gyrA7412c.111C>G0.400
gyrA7427c.126G>C0.479
gyrA7436c.135C>T0.338
gyrA7442c.141G>C0.425
gyrA7451c.150C>G0.405
gyrA7457c.156T>C0.389
gyrA7475c.174A>G0.240
gyrA7480p.Phe60Tyr0.216
gyrA7484c.183T>C0.216
gyrA7496c.195C>G0.167
gyrA7523c.222C>G0.186
gyrA7526c.225G>C0.119
gyrA7532c.231T>C0.163
gyrA7541c.240C>G0.146
gyrA7547c.246C>T0.154
gyrA7585p.Ser95Thr1.000
gyrA7601c.300C>G0.154
gyrA7607c.306C>G0.160
gyrA7694c.393A>G0.390
gyrA7697c.396C>G0.442
gyrA7710c.409T>C0.458
gyrA7728c.427A>C0.528
gyrA7763c.462T>C0.691
gyrA7775c.474C>A0.638
gyrA7781c.480G>C0.609
gyrA7784c.483A>G0.662
gyrA7790c.489G>C0.618
gyrA7793c.492G>C0.627
gyrA7796c.495G>C0.636
gyrA7799c.498A>G0.676
gyrA7814c.513C>G0.693
gyrA7823c.522G>C0.653
gyrA7832c.531G>T0.648
gyrA7835c.534A>C0.647
gyrA7853c.552C>G0.574
gyrA7859c.558A>G0.549
gyrA7865c.564T>C0.534
gyrA7886c.585T>C0.462
gyrA7898p.Asp199Glu0.150
gyrA8051c.750C>G0.200
gyrA8054c.753T>C0.208
gyrA8057c.756A>G0.208
gyrA8069c.768T>C0.543
gyrA8078c.777A>G0.543
gyrA8090c.789C>A0.541
gyrA8096c.795T>A0.541
gyrA8099c.798T>C0.550
gyrA8111c.810G>C0.561
gyrA8121c.820T>C0.596
gyrA8129c.828T>C0.587
gyrA8135c.834C>G0.604
gyrA8156c.855T>C0.667
gyrA8168c.867A>G0.619
gyrA8177c.876A>C0.659
gyrA8186c.885G>A0.565
gyrA8189c.888G>C0.543
gyrA8198c.897T>C0.581
gyrA8207c.906T>C0.568
gyrA8219c.918T>C0.522
gyrA8225c.924T>C0.531
gyrA8234c.933T>C0.480
gyrA8237c.936A>G0.480
gyrA8247p.Ile316Val0.491
gyrA8264c.963T>C0.500
gyrA8267c.966G>C0.490
gyrA8270c.969G>C0.490
gyrA8283p.Ile328Leu0.480
gyrA8288c.987T>C0.500
gyrA8294c.993T>C0.542
gyrA8324c.1023T>C0.588
gyrA8330c.1029C>G0.545
gyrA8339c.1038A>G0.576
gyrA8340p.Ala347Ser0.561
gyrA8372c.1071G>C0.541
gyrA8375c.1074G>C0.552
gyrA8382p.Leu361Met0.604
gyrA8387c.1086C>T0.566
gyrA8391p.Tyr364His0.600
gyrA8399c.1098T>G0.612
gyrA8401p.Asp367Ala0.612
gyrA8405c.1104C>T0.620
gyrA8420c.1119T>C0.667
gyrA8442c.1141C>T0.695
gyrA8453c.1152A>C0.607
gyrA8462c.1161A>C0.549
gyrA8465c.1164C>G0.509
gyrA8471c.1170T>C0.527
gyrA8472c.1171C>T0.491
gyrA8480c.1179C>A0.442
gyrA8486c.1185T>C0.481
gyrA8504c.1203G>C0.333
gyrA8516c.1215T>C0.386
gyrA8519c.1218A>C0.317
gyrA8520c.1219C>T0.356
gyrA8528c.1227G>C0.306
gyrA8543c.1242C>G0.340
gyrA8546c.1245T>C0.327
gyrA8552c.1251C>A0.389
gyrA8561c.1260A>G0.276
gyrA8576c.1275C>G0.214
gyrA8579c.1278C>T0.214
gyrA8588c.1287G>A0.429
gyrA8597c.1296C>G0.439
gyrA8603c.1302A>G0.471
gyrA8619c.1318T>C0.364
gyrA8624c.1323G>C0.426
gyrA8633c.1332C>G0.135
gyrA8636c.1335A>C0.547
gyrA8642c.1341A>G0.418
gyrA8672c.1371A>G0.519
gyrA8678c.1377G>A0.423
gyrA8693c.1392T>C0.477
gyrA8696c.1395G>C0.442
gyrA8699c.1398A>G0.419
gyrA8711c.1410A>C0.419
gyrA8714c.1413A>G0.409
gyrA8729c.1428T>C0.371
gyrA8730p.Gly477Arg0.333
gyrA8740p.Arg480His0.294
gyrA8747c.1446A>G0.233
gyrA8750c.1449C>G0.194
gyrA8751p.Ala484Ser0.182
gyrA8756c.1455A>G0.206
gyrA8762c.1461G>C0.176
gyrA8767p.Arg489Lys0.167
gyrA8780p.Asp493Glu0.175
gyrA8786c.1485T>C0.205
gyrA8801c.1500G>C0.152
gyrA8807c.1506C>T0.132
gyrA8810c.1509A>G0.139
gyrA8816c.1515C>G0.167
gyrA8818p.Ser506Asn0.179
gyrA8828c.1527T>C0.360
gyrA8837c.1536C>T0.327
gyrA8852c.1551T>C0.410
gyrA8858c.1557T>C0.413
gyrA8867c.1566A>G0.444
gyrA8870c.1569G>C0.438
gyrA8873c.1572A>C0.455
gyrA8891c.1590G>A0.442
gyrA8897c.1596T>C0.506
gyrA8903c.1602T>C0.557
gyrA8933c.1632G>C0.536
gyrA8939c.1638T>C0.547
gyrA8942c.1641G>C0.516
gyrA8946c.1645T>C0.531
gyrA8966c.1665C>G0.418
gyrA8967p.Ala556Arg0.442
gyrA8987c.1686C>G0.460
gyrA8990c.1689C>G0.426
gyrA8996c.1695T>C0.362
gyrA8998p.Leu566Trp0.429
gyrA9017c.1716C>G0.422
gyrA9023c.1722A>C0.395
gyrA9029c.1728T>C0.314
gyrA9032c.1731T>C0.265
gyrA9035c.1734G>C0.324
gyrA9050p.Asp583Glu0.143
gyrA9051c.1750T>C0.200
gyrA9056c.1755C>G0.200
gyrA9062c.1761C>G0.241
gyrA9068c.1767G>T0.212
gyrA9071c.1770G>C0.219
gyrA9080c.1779G>T0.342
gyrA9089c.1788G>C0.278
gyrA9099c.1798T>C0.359
gyrA9104c.1803C>G0.256
gyrA9119c.1818A>G0.395
gyrA9122c.1821C>G0.279
gyrA9143c.1842T>C0.375
gyrA9149c.1848C>T0.111
gyrA9152c.1851C>T0.217
gyrA9153p.Thr618Glu0.318
gyrA9158c.1857C>T0.196
gyrA9161c.1860C>G0.214
gyrA9182c.1881T>C0.462
gyrA9191c.1890G>A0.452
gyrA9200c.1899A>G0.490
gyrA9204p.Ser635Thr0.481
gyrA9224c.1923C>T0.448
gyrA9230c.1929T>C0.436
gyrA9233c.1932C>G0.426
gyrA9239c.1938C>T0.483
gyrA9252p.Val651Ile0.492
gyrA9284c.1983T>C0.578
gyrA9291c.1990C>T0.525
gyrA9296c.1995T>C0.516
gyrA9299c.1998G>C0.508
gyrA9300p.Ala667Ser0.541
gyrA9304p.Gly668Asp0.984
gyrA9308p.Asp669Glu0.492
gyrA9323c.2022C>G0.549
gyrA9335c.2034G>C0.592
gyrA9365c.2064G>A0.525
gyrA9374c.2073G>C0.500
gyrA9377c.2076A>G0.460
gyrA9383c.2082T>G0.478
gyrA9386c.2085T>C0.489
gyrA9395c.2094G>C0.479
gyrA9398c.2097T>C0.457
gyrA9413c.2112G>C0.436
rpoB759606c.-201T>C0.603
rpoB759629c.-178T>C0.564
rpoB759644c.-163T>A0.547
rpoB759647c.-160T>C0.551
rpoB759656c.-151A>C0.333
rpoB759657c.-150G>C0.312
rpoB759659c.-148T>A0.312
rpoB759660c.-147T>C0.312
rpoB759662c.-145C>T0.312
rpoB759667c.-140C>T0.312
rpoB759670c.-137C>T0.303
rpoB759671c.-136G>T0.303
rpoB759672c.-135G>C0.303
rpoB759683c.-124T>C0.303
rpoB759701c.-106A>T0.312
rpoB760060p.Tyr85Leu0.147
rpoB760067c.261G>C0.250
rpoB760070c.264T>G0.257
rpoB760091c.285G>C0.410
rpoB760101c.295T>C0.410
rpoB760112c.306T>C0.486
rpoB760118c.312T>G0.471
rpoB760121c.315T>C0.436
rpoB760130p.Asp108Glu0.595
rpoB760139c.333A>G0.600
rpoB760142c.336C>G0.600
rpoB760181c.375T>C0.659
rpoB760184c.378A>G0.667
rpoB760196c.390C>G0.707
rpoB760223c.417T>C0.674
rpoB760235c.429T>C0.725
rpoB760283c.477G>C0.702
rpoB760298c.492G>C0.566
rpoB760307c.501T>C0.725
rpoB760310c.504G>C0.585
rpoB760313c.507G>C0.148
rpoB760328c.522G>C0.522
rpoB760331c.525G>C0.717
rpoB760337c.531C>G0.170
rpoB760340c.534G>T0.614
rpoB760361c.555T>C0.689
rpoB760370c.564C>G0.683
rpoB760376p.Asp190Glu0.661
rpoB760380p.Thr192Leu0.655
rpoB760406c.600G>C0.612
rpoB760412c.606C>G0.514
rpoB760415c.609C>T0.125
rpoB760424c.618C>G0.625
rpoB760430c.624T>C0.648
rpoB760475c.669A>G0.570
rpoB760481c.675G>C0.562
rpoB760484c.678A>G0.577
rpoB760522p.Ser239Asn0.565
rpoB760532c.726T>C0.529
rpoB760533p.Val243Thr0.484
rpoB760541c.735G>C0.521
rpoB760547c.741G>C0.608
rpoB760563p.Arg253Met0.593
rpoB760591p.Val262Ala0.661
rpoB760611c.805T>C0.621
rpoB760646c.840C>G0.692
rpoB760655c.849A>G0.691
rpoB760661c.855A>C0.712
rpoB760670c.864G>C0.632
rpoB760674c.868T>C0.623
rpoB760679c.873A>G0.581
rpoB760683c.877T>C0.614
rpoB760715c.909C>G0.459
rpoB760718c.912C>T0.459
rpoB760724c.918T>C0.525
rpoB760730c.924T>C0.518
rpoB760751c.945G>C0.464
rpoB760757c.951T>C0.367
rpoB760759p.Val318Ala0.354
rpoB760769c.963C>G0.378
rpoB760775c.969G>C0.326
rpoB760776c.970T>A0.326
rpoB760793c.987A>G0.508
rpoB760805c.999G>C0.550
rpoB760817c.1011A>G0.481
rpoB760820c.1014T>C0.491
rpoB760826c.1020C>G0.532
rpoB760830c.1024T>C0.511
rpoB760841c.1035T>C0.522
rpoB760845p.Thr347Pro0.511
rpoB760859c.1053T>C0.500
rpoB760862c.1056G>C0.510
rpoB760869p.Val355Ile0.581
rpoB760886c.1080A>G0.600
rpoB760910c.1104C>T0.110
rpoB760925c.1119T>C0.621
rpoB760928c.1122G>C0.493
rpoB760931c.1125C>G0.500
rpoB760934c.1128C>T0.621
rpoB760938c.1132C>T0.114
rpoB760946c.1140A>G0.653
rpoB760982c.1176G>C0.632
rpoB760985c.1179G>C0.609
rpoB760991c.1185G>C0.644
rpoB761006c.1200C>G0.687
rpoB761015c.1209G>C0.700
rpoB761021c.1215G>C0.710
rpoB761027c.1221A>G0.743
rpoB761036c.1230G>C0.653
rpoB761037c.1231T>C0.667
rpoB761057c.1251G>C0.638
rpoB761102c.1296A>G0.649
rpoB761129c.1323G>C0.584
rpoB761132c.1326G>T0.589
rpoB761133c.1327T>C0.605
rpoB761150c.1344A>C0.622
rpoB761153c.1347G>C0.547
rpoB761165c.1359G>C0.616
rpoB761180c.1374A>C0.714
rpoB761189c.1383T>C0.703
rpoB761195c.1389G>C0.629
rpoB761207c.1401C>T0.639
rpoB761213c.1407G>C0.647
rpoB761219c.1413G>C0.629
rpoB761249c.1443A>G0.723
rpoB761255c.1449T>G0.698
rpoB761261c.1455G>T0.600
rpoB761264c.1458C>G0.113
rpoB761306c.1500C>G0.656
rpoB761327c.1521A>G0.614
rpoB761330c.1524G>C0.545
rpoB761354c.1548C>T0.540
rpoB761360c.1554T>C0.500
rpoB761362p.Ser519Thr0.500
rpoB761373p.Val523His0.511
rpoB761408c.1602G>C0.408
rpoB761411c.1605G>A0.340
rpoB761414c.1608A>G0.533
rpoB761423c.1617T>C0.533
rpoB761435c.1629T>C0.406
rpoB761438c.1632G>C0.219
rpoB761439p.Asp545Lys0.406
rpoB761444c.1638T>C0.406
rpoB761447c.1641C>G0.394
rpoB761452p.Val549Glu0.382
rpoB761457p.Pro551Ser0.382
rpoB761465c.1659G>C0.585
rpoB761477c.1671C>G0.640
rpoB761486c.1680C>T0.132
rpoB761492c.1686G>C0.683
rpoB761504c.1698C>G0.109
rpoB761510c.1704T>C0.769
rpoB761531c.1725C>G0.771
rpoB761537c.1731C>G0.750
rpoB761570c.1764T>C0.662
rpoB761573c.1767C>G0.655
rpoB761579c.1773G>C0.659
rpoB761588c.1782C>T0.612
rpoB761606c.1800C>G0.649
rpoB761612c.1806G>C0.629
rpoB761615c.1809A>C0.632
rpoB761636c.1830G>T0.659
rpoB761645c.1839C>G0.627
rpoB761648c.1842T>C0.616
rpoB761657c.1851C>G0.609
rpoB761675c.1869G>C0.605
rpoB761720c.1914C>G0.350
rpoB761725p.Glu640Ala0.324
rpoB761732c.1926C>G0.324
rpoB761735c.1929C>G0.325
rpoB761747c.1941G>C0.500
rpoB761750c.1944G>C0.462
rpoB761765c.1959T>C0.500
rpoB761772p.His656Ala0.491
rpoB761778p.Asn658Asp0.491
rpoB761791p.Arg662His0.509
rpoB761813c.2007T>C0.548
rpoB761815p.Ala670Glu0.532
rpoB761834c.2028T>C0.565
rpoB761848p.Cys681Ser0.586
rpoB761852c.2046C>G0.594
rpoB761858c.2052G>C0.557
rpoB761873c.2067A>C0.587
rpoB761885c.2079T>C0.625
rpoB761906c.2100C>G0.612
rpoB761909c.2103T>C0.627
rpoB761912c.2106T>C0.612
rpoB761915p.Asp703Glu0.603
rpoB761916p.Asp704Asn0.603
rpoB761948c.2142G>C0.653
rpoB761954c.2148C>G0.722
rpoB762008c.2202C>T0.737
rpoB762014c.2208C>T0.821
rpoB762017c.2211A>G0.831
rpoB762053c.2247T>C0.836
rpoB762062c.2256T>C0.868
rpoB762065c.2259T>C0.717
rpoB762083c.2277T>C0.821
rpoB762086c.2280G>C0.800
rpoB762101c.2295C>G0.754
rpoB762114p.Ile770Val0.742
rpoB762131c.2325C>G0.712
rpoB762140c.2334G>C0.704
rpoB762143c.2337T>C0.714
rpoB762149c.2343G>C0.708
rpoB762167c.2361T>C0.671
rpoB762176c.2370T>C0.680
rpoB762185c.2379G>C0.671
rpoB762206c.2400C>G0.610
rpoB762233c.2427G>C0.620
rpoB762246c.2440C>T0.580
rpoB762254c.2448T>G0.617
rpoB762257c.2451C>G0.629
rpoB762266c.2460T>C0.629
rpoB762284c.2478G>C0.632
rpoB762293c.2487T>C0.607
rpoB762314c.2508C>T0.509
rpoB762317c.2511A>G0.621
rpoB762329c.2523G>C0.667
rpoB762338c.2532T>C0.654
rpoB762347c.2541T>C0.655
rpoB762362p.Glu852Asp0.632
rpoB762369c.2563T>C0.632
rpoB762395c.2589G>C0.540
rpoB762398c.2592T>C0.596
rpoB762401c.2595G>C0.596
rpoB762404c.2598T>C0.596
rpoB762410c.2604T>G0.511
rpoB762413c.2607G>A0.426
rpoB762416c.2610A>G0.593
rpoB762419c.2613C>G0.509
rpoB762434c.2628T>C0.638
rpoB762449c.2643C>A0.652
rpoB762467c.2661C>T0.625
rpoB762488c.2682G>C0.656
rpoB762489p.Val895Gln0.583
rpoB762509c.2703T>G0.597
rpoB762510p.Ala902Pro0.597
rpoB762521c.2715C>T0.557
rpoB762533c.2727T>C0.500
rpoB762536c.2730T>C0.458
rpoB762537c.2731T>C0.458
rpoB762551c.2745C>G0.432
rpoB762581c.2775T>C0.282
rpoB762582c.2776T>C0.282
rpoB762729p.Gln975Lys0.152
rpoB762736p.Ala977Glu0.147
rpoB762743c.2937G>T0.161
rpoB762744p.Gln980Ala0.161
rpoB762750p.Leu982Met0.200
rpoB762753c.2947T>C0.278
rpoB762758c.2952G>C0.297
rpoB762782c.2976T>C0.429
rpoB762785p.Asp993Glu0.429
rpoB762788c.2982G>C0.417
rpoB762789p.Leu995Met0.444
rpoB762794c.2988C>G0.485
rpoB762799p.Ala998Gly0.514
rpoB762810p.Ala1002Ser0.432
rpoB762813p.Met1003Val0.514
rpoB762818c.3012C>G0.444
rpoB762827c.3021G>C0.614
rpoB762857c.3051C>G0.632
rpoB762860c.3054G>C0.544
rpoB762863c.3057T>C0.569
rpoB762929c.3123G>C0.730
rpoB762962c.3156C>T0.131
rpoB762989c.3183G>C0.627
rpoB762995c.3189G>T0.727
rpoB763013c.3207C>G0.567
rpoB763028c.3222T>C0.648
rpoB763031c.3225T>G0.340
rpoB763034c.3228C>G0.648
rpoB763040c.3234C>G0.679
rpoB763070c.3264T>C0.694
rpoB763076c.3270C>G0.109
rpoB763085c.3279C>G0.662
rpoB763115c.3309T>C0.609
rpoB763127c.3321G>C0.106
rpoB763136c.3330C>T0.530
rpoB763148c.3342G>C0.531
rpoB763158c.3352C>T0.567
rpoB763166c.3360A>G0.724
rpoB763169c.3363A>G0.143
rpoB763187c.3381C>G0.154
rpoB763190c.3384C>T0.566
rpoB763202c.3396A>G0.556
rpoB763205c.3399G>C0.452
rpoB763206c.3400A>T0.634
rpoB763214c.3408T>C0.680
rpoB763226c.3420A>G0.500
rpoB763227c.3421C>T0.491
rpoB763238c.3432T>C0.647
rpoB763253c.3447G>C0.462
rpoB763256c.3450G>A0.462
rpoB763262c.3456C>T0.137
rpoB763268c.3462C>G0.451
rpoB763283c.3477T>C0.467
rpoB763284c.3478C>T0.467
rpoC763351c.-19T>C0.465
rpoC763352c.-18T>A0.465
rpoC763402c.33C>G0.525
rpoC763408c.39T>C0.163
rpoC763411c.42T>G0.583
rpoC763414c.45T>C0.600
rpoC763417c.48C>A0.154
rpoC763423c.54G>A0.151
rpoC763441c.72C>T0.623
rpoC763444c.75T>C0.623
rpoC763456c.87A>G0.600
rpoC763486c.117T>G0.593
rpoC763492c.123G>A0.456
rpoC763528c.159G>A0.574
rpoC763546c.177A>G0.592
rpoC763570c.201G>C0.583
rpoC763573c.204G>C0.590
rpoC763594c.225C>T0.661
rpoC763603c.234C>T0.564
rpoC763633c.264T>C0.115
rpoC763636c.267T>C0.698
rpoC763657c.288G>A0.609
rpoC763660c.291T>G0.702
rpoC763675c.306C>G0.689
rpoC763696c.327T>C0.658
rpoC763702c.333C>G0.705
rpoC763717c.348T>C0.708
rpoC763723c.354G>C0.673
rpoC763732c.363C>G0.574
rpoC763738c.369G>A0.488
rpoC763741c.372C>T0.600
rpoC763744c.375G>C0.617
rpoC763765c.396T>C0.691
rpoC763774c.405G>C0.684
rpoC763807c.438T>C0.717
rpoC763816c.447C>G0.672
rpoC763835p.Ala156Met0.672
rpoC763853p.Val162Ile0.656
rpoC763858c.489A>G0.651
rpoC763872p.Gly168Ala0.629
rpoC763876p.Glu169Asp0.623
rpoC763879c.510A>G0.633
rpoC763888c.519G>C0.615
rpoC763891c.522G>C0.533
rpoC763894c.525A>G0.613
rpoC763900c.531G>C0.559
rpoC763945c.576T>C0.625
rpoC763951c.582G>C0.620
rpoC763960c.591T>C0.618
rpoC763987c.618C>T0.500
rpoC763991p.Ile208Leu0.589
rpoC763996c.627T>C0.596
rpoC764002c.633C>G0.529
rpoC764005c.636G>C0.603
rpoC764024c.655T>C0.630
rpoC764032p.Asp221Glu0.481
rpoC764040p.Ser224Thr0.511
rpoC764044c.675T>C0.577
rpoC764059c.690G>T0.595
rpoC764083c.714A>G0.647
rpoC764089c.720C>T0.157
rpoC764098c.729A>G0.638
rpoC764101c.732C>G0.500
rpoC764102p.Val245Ile0.489
rpoC764112p.Tyr248Phe0.520
rpoC764116c.747C>T0.519
rpoC764131c.762T>C0.672
rpoC764152c.783C>T0.127
rpoC764161c.792G>C0.115
rpoC764188c.819A>G0.534
rpoC764194p.Glu275Asp0.105
rpoC764195p.Ser276Ile0.404
rpoC764203c.834G>C0.491
rpoC764206c.837T>C0.491
rpoC764215c.846A>G0.453
rpoC764236c.867G>A0.500
rpoC764248c.879C>G0.500
rpoC764257c.888G>C0.500
rpoC764266c.897T>C0.561
rpoC764269c.900G>C0.544
rpoC764272c.903G>C0.551
rpoC764278c.909A>G0.549
rpoC764338c.969G>A0.549
rpoC764353c.984G>C0.571
rpoC764365c.996C>T0.620
rpoC764380c.1011G>C0.533
rpoC764381c.1012T>A0.525
rpoC764387c.1018T>C0.484
rpoC764405c.1036A>C0.574
rpoC764419c.1050C>G0.471
rpoC764428c.1059G>C0.522
rpoC764431c.1062G>C0.508
rpoC764434c.1065A>G0.500
rpoC764446c.1077T>C0.524
rpoC764449c.1080G>C0.524
rpoC764452c.1083T>C0.538
rpoC764458c.1089G>C0.523
rpoC764461c.1092A>G0.567
rpoC764489c.1120C>T0.522
rpoC764497c.1128A>G0.582
rpoC764510c.1141C>T0.508
rpoC764521c.1152T>C0.635
rpoC764527c.1158C>T0.540
rpoC764536c.1167G>C0.629
rpoC764539c.1170C>G0.633
rpoC764548c.1179G>A0.518
rpoC764551c.1182G>C0.500
rpoC764554c.1185C>T0.492
rpoC764560c.1191T>C0.517
rpoC764566c.1197C>G0.508
rpoC764575c.1206T>G0.603
rpoC764585c.1216C>T0.107
rpoC764593c.1224C>T0.433
rpoC764602c.1233C>T0.167
rpoC764611c.1242G>T0.521
rpoC764626c.1257C>T0.172
rpoC764632c.1263T>C0.164
rpoC764650c.1281G>C0.491
rpoC764651c.1282T>A0.433
rpoC764752c.1383G>C0.620
rpoC764764c.1395T>C0.611
rpoC764803c.1434C>G0.154
rpoC764809c.1440C>T0.712
rpoC764815c.1446A>G0.712
rpoC764824c.1455T>C0.200
rpoC764827c.1458G>C0.550
rpoC764830c.1461C>G0.197
rpoC764858c.1489T>C0.786
rpoC764872c.1503A>G0.593
rpoC764888c.1519T>C0.746
rpoC764893c.1524T>C0.111
rpoC764911c.1542A>G0.667
rpoC764932c.1563C>A0.731
rpoC764948c.1579T>C0.698
rpoC764968c.1599T>C0.706
rpoC764995c.1626C>G0.648
rpoC765007c.1638T>G0.576
rpoC765008c.1639T>C0.522
rpoC765011c.1642A>T0.522
rpoC765019c.1650A>G0.590
rpoC765034c.1665T>C0.571
rpoC765040c.1671T>C0.573
rpoC765041c.1672T>C0.568
rpoC765047c.1678T>C0.575
rpoC765055c.1686C>G0.575
rpoC765073c.1704G>C0.567
rpoC765076c.1707A>G0.493
rpoC765079c.1710T>G0.541
rpoC765082c.1713G>C0.551
rpoC765089c.1720T>C0.597
rpoC765103c.1734G>T0.531
rpoC765292c.1923G>C0.565
rpoC765298c.1929G>C0.549
rpoC765300p.Val644Ala0.556
rpoC765319c.1950A>G0.550
rpoC765326p.His653Ala0.535
rpoC765330p.Ser654Asn0.514
rpoC765346c.1977C>G0.485
rpoC765349c.1980T>C0.531
rpoC765352c.1983G>C0.540
rpoC765383p.Met672Leu0.569
rpoC765404p.Leu679Val0.586
rpoC765409c.2040T>C0.561
rpoC765421c.2052C>G0.561
rpoC765451c.2082C>A0.475
rpoC765478c.2109T>C0.478
rpoC765499c.2130C>G0.558
rpoC765529c.2160C>T0.527
rpoC765541c.2172C>G0.525
rpoC765553c.2184C>T0.483
rpoC765556c.2187G>C0.482
rpoC765559c.2190G>C0.491
rpoC765580c.2211G>C0.517
rpoC765613p.His748Gln0.574
rpoC765625c.2256C>G0.570
rpoC765631p.Asp754Glu0.558
rpoC765700c.2331T>C0.627
rpoC765734c.2365T>C0.721
rpoC765739c.2370G>T0.717
rpoC765751c.2382C>G0.593
rpoC765753p.Asp795Ala0.640
rpoC765772c.2403C>G0.661
rpoC765784c.2415C>G0.585
rpoC765787c.2418C>T0.653
rpoC765793c.2424C>G0.667
rpoC765796c.2427C>T0.680
rpoC765811c.2442T>C0.720
rpoC765814c.2445A>G0.720
rpoC765826c.2457T>C0.731
rpoC765835c.2466C>T0.724
rpoC765850c.2481G>C0.636
rpoC765883c.2514C>G0.667
rpoC765886c.2517C>G0.647
rpoC765892c.2523T>C0.648
rpoC765937c.2568T>C0.650
rpoC765947c.2578T>C0.600
rpoC765967c.2598C>T0.469
rpoC765982c.2613C>G0.446
rpoC765994c.2625A>T0.492
rpoC766010c.2641T>A0.508
rpoC766021c.2652G>C0.500
rpoC766027c.2658G>C0.523
rpoC766043p.Gln892Glu0.548
rpoC766054c.2685C>G0.456
rpoC766082p.Ala905Gln0.500
rpoC766096c.2727G>C0.548
rpoC766129c.2760C>G0.603
rpoC766135c.2766G>A0.484
rpoC766141c.2772C>T0.458
rpoC766142c.2773C>T0.458
rpoC766174p.Asn935Lys0.447
rpoC766178p.Ile937Val0.543
rpoC766207c.2838T>C0.150
rpoC766216c.2847T>C0.182
rpoC766222c.2853T>C0.190
rpoC766226c.2857T>C0.200
rpoC766231c.2862T>G0.238
rpoC766237c.2868T>C0.250
rpoC766243c.2874C>A0.261
rpoC766258c.2889T>C0.318
rpoC766270c.2901G>C0.261
rpoC766273c.2904T>C0.261
rpoC766274p.Ala969Thr0.250
rpoC766279c.2910C>G0.231
rpoC766280p.Ser971Gly0.231
rpoC766315c.2946C>G0.176
rpoC766321c.2952C>G0.184
rpoC766327c.2958C>A0.150
rpoC766345c.2976T>C0.429
rpoC766348c.2979A>G0.423
rpoC766357c.2988C>T0.283
rpoC766363c.2994G>C0.463
rpoC766366c.2997C>G0.481
rpoC766381c.3012C>T0.500
rpoC766384c.3015A>G0.509
rpoC766387c.3018C>G0.125
rpoC766390c.3021C>T0.441
rpoC766393c.3024C>G0.597
rpoC766408c.3039C>G0.590
rpoC766411c.3042C>G0.537
rpoC766426c.3057C>T0.690
rpoC766447c.3078T>C0.783
rpoC766462c.3093G>C0.634
rpoC766483c.3114G>C0.731
rpoC766484p.Val1039Ile0.644
rpoC766492c.3123T>C0.731
rpoC766495c.3126C>T0.117
rpoC766522c.3153C>G0.739
rpoC766528c.3159T>C0.688
rpoC766531c.3162G>C0.657
rpoC766540p.Asp1057Glu0.694
rpoC766549c.3180G>C0.649
rpoC766573c.3204T>C0.627
rpoC766582c.3213C>G0.540
rpoC766583p.Gly1072Ser0.519
rpoC766591c.3222A>G0.538
rpoC766594c.3225G>C0.547
rpoC766597c.3228C>G0.586
rpoC766607p.Ile1080Leu0.662
rpoC766630c.3261G>C0.675
rpoC766657c.3288A>G0.705
rpoC766672c.3303T>C0.649
rpoC766673p.Gly1102Asn0.589
rpoC766684c.3315C>T0.582
rpoC766726c.3357T>C0.642
rpoC766738c.3369G>C0.628
rpoC766765c.3396A>C0.594
rpoC766774c.3405T>C0.627
rpoC766801c.3432C>G0.514
rpoC766804c.3435A>G0.630
rpoC766861c.3492G>C0.725
rpoC766864c.3495G>C0.706
rpoC766900c.3531T>C0.704
rpoC766933c.3564A>G0.658
rpoC766945c.3576A>G0.654
rpoC766963c.3594T>C0.627
rpoC766972c.3603G>C0.592
rpoC766996c.3627C>T0.565
rpoC767009c.3640T>A0.441
rpoC767014c.3645G>C0.424
rpoC767033c.3664T>A0.500
rpoC767059c.3690T>G0.538
rpoC767062c.3693C>A0.550
rpoC767098c.3729T>C0.577
rpoC767119c.3750A>G0.589
rpoC767134c.3765C>A0.620
rpoC767158c.3789T>C0.631
rpoC767180p.Ala1271Gln0.611
rpoC767191c.3822C>G0.620
rpoC767206c.3837C>G0.531
rpoC767209c.3840T>C0.524
rpoC767212c.3843G>C0.524
rpoC767221c.3852C>G0.554
rpoC767230c.3861G>C0.538
rpoC767233c.3864T>C0.509
rpoC767263c.3894T>C0.278
rpoC767264p.Ala1299Gln0.278
rpoC767275c.3906T>C0.241
rpoC767278c.3909T>C0.286
rpoC767281c.3912C>G0.278
rpoC767284c.3915C>T0.278
rpoC767288c.3919C>T0.206
rpsL781395c.-165T>C1.000
rpsL781571c.12C>T0.615
rpsL781595c.36T>C0.667
rpsL781605p.Ile16Val0.667
rpsL781608p.Ser17Ala0.651
rpsL781628c.69T>C0.745
rpsL781631c.72G>C0.714
rpsL781649c.90T>C0.736
rpsL781655c.96T>C0.750
rpsL781700c.141G>C0.643
rpsL781703c.144G>T0.618
rpsL781715c.156T>C0.709
rpsL781728c.169T>C0.679
rpsL781736c.177T>C0.647
rpsL781742c.183C>T0.564
rpsL781748c.189C>G0.571
rpsL781760c.201T>C0.604
rpsL781772c.213C>A0.531
rpsL781808c.249C>T0.544
rpsL781811c.252C>T0.638
rpsL781832c.273T>C0.712
rpsL781835c.276T>C0.119
rpsL781838c.279G>C0.576
rpsL781841c.282C>G0.585
rpsL781865c.306G>C0.655
rpsL781868c.309T>C0.655
rpsL781871c.312G>C0.643
rpsL781877c.318T>C0.612
rpsL781880c.321C>G0.150
rpsL781889c.330C>G0.161
rpsL781892c.333A>G0.698
rpsL781898c.339A>T0.687
rpsL781913c.354C>T0.155
rpsL781916c.357T>C0.716
rpsL781929p.Gly124Ser0.733
rpsL781933374G>A0.162
rplC800794c.-15A>G0.523
rplC800796c.-13A>G0.512
rplC800814c.6A>G0.595
rplC800817c.9A>T0.600
rplC800844c.36T>C0.569
rplC800865c.57A>G0.477
rplC800867p.Ser20Asn0.488
rplC800874c.66A>G0.444
rplC800875p.Val23Ile0.444
rplC800880c.72A>G0.435
rplC800889c.81C>G0.455
rplC800892c.84G>C0.465
rplC800907c.99C>G0.442
rplC800916c.108A>G0.390
rplC800934c.126C>G0.182
rplC800937c.129A>G0.182
rplC800939p.Arg44Gln0.182
rplC800946c.138T>C0.171
rplC800949c.141T>C0.171
rplC801114c.306C>G0.148
rplC801117c.309G>C0.143
rplC801127p.Ala107Thr0.282
rplC801132c.324T>C0.351
rplC801147c.339T>C0.415
rplC801150c.342G>C0.366
rplC801153c.345G>C0.415
rplC801156c.348T>A0.419
rplC801168c.360C>G0.438
rplC801171c.363A>G0.479
rplC801174c.366T>C0.490
rplC801180c.372C>G0.482
rplC801195c.387G>C0.593
rplC801201c.393C>T0.569
rplC801207c.399C>T0.565
rplC801246c.438C>T0.493
rplC801249c.441T>C0.541
rplC801255c.447C>T0.618
rplC801264c.456C>T0.426
rplC801267c.459A>T0.491
rplC801270c.462T>C0.554
rplC801276c.468G>C0.536
rplC801279c.471G>C0.526
rplC801282c.474G>C0.439
rplC801285c.477G>C0.456
rplC801300c.492C>G0.530
rplC801309c.501C>G0.587
rplC801312c.504G>C0.600
rplC801321c.513C>T0.485
rplC801324c.516T>C0.544
rplC801339c.531T>C0.431
rplC801341p.Leu178Gln0.463
rplC801348c.540T>G0.483
rplC801357c.549T>C0.518
rplC801367p.Ala187Thr0.431
rplC801402c.594T>C0.472
rplC801405c.597T>C0.472
rplC801423c.615G>C0.468
rplC801426c.618C>G0.468
rplC801427p.Met207Val0.478
rplC801438c.630T>C0.477
rplC801442p.Ile212Val0.442
rrs1471923r.78t>c0.524
rrs1471925r.80t>c0.545
rrs1471932r.87a>g0.488
rrs1471934r.89a>g0.511
rrs1471969r.124t>c0.500
rrs1471970r.125g>a0.500
rrs1472028r.183a>t0.471
rrs1472029r.184c>t0.471
rrs1472030r.185g>t0.514
rrs1472031r.186g>a0.485
rrs1472033r.188a>g0.514
rrs1472034r.189t>c0.514
rrs1472044r.199g>t0.457
rrs1472045r.200t>a0.457
rrs1472061r.216a>t0.632
rrs1472075r.230a>g0.643
rrs1472108r.263c>t0.682
rrs1472969r.1124a>g0.643
rrs1472970r.1125c>g0.659
rrs1472977r.1132g>c0.610
rrs1472978r.1133t>c0.628
rrs1473105r.1260g>a0.491
rrs1473120r.1275c>ct0.388
rrs1473123r.1278a>t0.426
rrs1473145r.1300c>t0.467
rrs1473166r.1321g>a0.413
rrs1473290r.1445c>t0.630
rrl1473651c.-7GT>G0.500
rrl1473658r.1t>a0.457
rrl1473659r.2t>a0.457
rrl1473668r.11c>t0.532
rrl1473756r.99g>a0.605
rrl1473758r.101g>t0.611
rrl1473806r.149c>t0.689
rrl1473877r.220g>a0.634
rrl1473898r.241c>t0.718
rrl1473943r.286g>t0.583
rrl1473945r.288t>a0.559
rrl1473946r.289a>t0.559
rrl1473986r.329t>c0.568
rrl1473987r.330g>a0.581
rrl1473995r.338g>t0.644
rrl1474001r.344c>t0.653
rrl1474009r.352a>g0.660
rrl1474012r.355c>t0.673
rrl1474093r.436g>t0.711
rrl1474099r.442g>a0.681
rrl1474103r.446a>t0.735
rrl1474140r.483c>t0.730
rrl1474151r.494c>t0.694
rrl1474181r.524c>t0.609
rrl1474249r.592g>t0.531
rrl1474291r.634tttcctctccggagga>t0.600
rrl1474308r.651g>t0.545
rrl1474310r.653t>g0.545
rrl1474356r.699t>c0.793
rrl1474362r.705a>g0.815
rrl1474376r.719t>c0.808
rrl1474427r.770a>c0.500
rrl1474429r.772g>c0.500
rrl1474432r.775c>g0.476
rrl1474639r.982g>a0.651
rrl1474794r.1137c>t0.702
rrl1474812r.1155g>a0.729
rrl1474823r.1166c>t0.688
rrl1474831r.1174a>g0.725
rrl1474904r.1247g>a0.633
rrl1474956r.1299c>t0.500
rrl1474960r.1303c>g0.474
rrl1474963r.1306g>t0.472
rrl1474964r.1307t>a0.486
rrl1474965r.1308g>c0.474
rrl1474970r.1313g>a0.487
rrl1475006r.1349a>t0.556
rrl1475061r.1404c>t0.636
rrl1475088r.1431a>t0.738
rrl1475199r.1542g>a0.622
rrl1475206r.1549c>t0.634
rrl1475209r.1552g>c0.625
rrl1475213r.1556c>t0.561
rrl1475249r.1592t>c0.622
rrl1475252r.1595c>t0.658
rrl1475266r.1609t>c0.688
rrl1475267r.1610g>a0.688
rrl1475275r.1618c>t0.688
rrl1475276r.1619t>c0.688
rrl1475291r.1634a>c0.649
rrl1475315r.1658a>t0.679
rrl1475355r.1698c>t0.643
rrl1475369r.1712g>t0.690
rrl1475402r.1745c>t0.630
rrl1475419r.1762c>t0.656
rrl1475429r.1772g>a0.515
rrl1475436r.1779c>t0.679
rrl1475483r.1826c>t0.600
rrl1475505r.1848g>a0.500
rrl1475526r.1869c>a0.600
rrl1475599r.1942a>g0.800
rrl1475608r.1951t>c0.808
rrl1475642r.1985t>c0.871
rrl1475657r.2000a>g0.848
rrl1475659r.2002g>t0.848
rrl1475758r.2101ac>a0.750
rrl1475763r.2106c>t0.706
rrl1475765r.2108ag>a0.706
rrl1475881r.2224t>c0.750
rrl1475988r.2331a>g0.769
rrl1476031r.2374c>t0.519
rrl1476032r.2375c>a0.519
rrl1476033r.2376t>c0.519
rrl1476034r.2377c>a0.519
rrl1476045r.2388g>t0.500
rrl1476047r.2390g>t0.500
rrl1476048r.2391g>a0.500
rrl1476049r.2392c>t0.500
rrl1476086r.2429g>a0.700
rrl1476089r.2432t>c0.692
rrl1476095r.2438c>g0.744
rrl1476106r.2449a>t0.684
rrl1476115r.2458t>c0.643
rrl1476117r.2460g>c0.628
rrl1476214r.2557g>a0.469
rrl1476215r.2558c>t0.111
rrl1476224r.2567a>g0.541
rrl1476281r.2624t>c0.590
rrl1476583r.2926g>a0.702
rrl1476584r.2927c>t0.702
rrl1476594r.2937c>t0.647
rrl1476597r.2940g>a0.694
rrl1476603r.2946g>a0.660
rrl1476608r.2951c>g0.667
rrl1476628r.2971t>a0.696
rrl1476689r.3032a>t0.558
rrl1476690r.3033c>t0.558
rrl1476693r.3036g>a0.571
rrl1476695r.3038t>a0.558
rrl1476716r.3059a>c0.587
rrl1476726r.3069a>g0.578
rrl1476732r.3075t>c0.545
rrl1476750r.3093t>c0.462
rrl1476755r.3098g>a0.538
rrl1476759r.3102t>c0.528
rrl1476770r.3113t>c0.474
rrl1476771r.3114g>a0.462
fabG11673482p.Ser15Ala0.590
fabG11673487c.48T>C0.575
fabG11673490c.51A>G0.575
fabG11673523c.84G>T0.647
fabG11673535c.96A>G0.607
fabG11673547c.108T>C0.596
fabG11673568c.129C>G0.500
fabG11673574c.135C>G0.469
fabG11673580c.141T>G0.438
fabG11673589c.150A>G0.429
fabG11673595c.156A>C0.325
fabG11673596p.Lys53Glu0.333
fabG11673602c.163C>T0.297
fabG11673607c.168T>C0.324
fabG11673615p.Glu59Val0.297
fabG11673619c.180T>C0.270
fabG11673633p.Ser65Asn0.171
fabG11673637p.Asp66Glu0.152
fabG11673652c.213C>G0.118
fabG11673679c.240T>C0.244
fabG11673685c.246C>T0.256
fabG11673703c.264C>T0.310
fabG11673710p.Leu91Ile0.325
fabG11673716p.Ala93Lys0.317
fabG11673733p.Met98Ile0.317
fabG11673742c.303C>T0.310
fabG11673748c.309A>G0.302
fabG11673749p.Lys104Arg0.302
fabG11673758p.Lys107Glu0.310
fabG11673890p.Ala151Ser0.415
fabG11673901c.462A>G0.444
fabG11673905p.Ser156Ala0.455
fabG11673916c.477A>C0.482
fabG11673917p.Val160Leu0.483
fabG11673922c.483T>C0.526
fabG11673941p.Ala168Ser0.571
fabG11673955c.516G>C0.638
fabG11673961c.522A>C0.648
fabG11673985c.546C>G0.667
fabG11674006p.Asp189Glu0.677
fabG11674015c.576C>T0.596
fabG11674018c.579G>C0.614
fabG11674021c.582G>C0.628
fabG11674024c.585T>C0.628
fabG11674033c.594T>C0.614
fabG11674037p.Gln200Ala0.628
fabG11674042c.603G>T0.628
fabG11674049p.Gln204Asp0.667
fabG11674054c.615T>C0.667
fabG11674060c.621A>G0.674
fabG11674063c.624G>C0.667
fabG11674079p.Pro214Ala0.780
fabG11674114c.675T>A0.722
fabG11674123c.684T>C0.638
fabG11674126c.687G>C0.630
fabG11674132c.693T>C0.609
fabG11674136p.Ser233Ala0.609
fabG11674141c.702T>C0.609
fabG11674156c.717C>G0.578
fabG11674171c.732T>C0.488
inhA1674199c.-3C>G0.154
inhA1674205p.Thr2Ala0.154
inhA1674216c.15G>C0.143
inhA1674219p.Asp6Glu0.133
inhA1674229p.Ile10Val0.171
inhA1674237c.36T>C0.188
inhA1674243c.42A>G0.182
inhA1674279c.78A>C0.143
inhA1674280p.Arg27Lys0.143
inhA1674285c.84A>G0.143
inhA1674295p.Gln32Ala0.143
inhA1674300c.99C>G0.138
inhA1674303c.102C>G0.138
inhA1674307c.106C>T0.143
inhA1674315c.114C>G0.138
inhA1674342c.141T>C0.130
inhA1674471c.270G>C0.500
inhA1674480c.279T>C0.511
inhA1674486c.285T>C0.533
inhA1674504c.303C>G0.551
inhA1674537c.336C>G0.612
inhA1674542p.Ala114Glu0.604
inhA1674546c.345T>C0.587
inhA1674549c.348G>C0.560
inhA1674552c.351C>G0.520
inhA1674555c.354G>A0.520
inhA1674561c.360C>T0.611
inhA1674582c.381T>C0.564
inhA1674585c.384T>C0.625
inhA1674589p.Met130Leu0.644
inhA1674601p.Leu134Thr0.586
inhA1674624c.423A>C0.698
inhA1674630c.429C>G0.641
inhA1674660c.459G>C0.629
inhA1674672c.471C>G0.607
inhA1674703c.502T>C0.625
inhA1674708c.507G>A0.608
inhA1674718c.517A>C0.623
inhA1674723c.522C>T0.596
inhA1674738c.537C>G0.458
inhA1674741c.540C>T0.438
inhA1674746p.Tyr182Phe0.431
inhA1674750c.549T>C0.400
inhA1674753c.552G>C0.377
inhA1674756c.555T>C0.389
inhA1674759c.558G>C0.396
inhA1674774c.573A>G0.524
inhA1674780c.579T>G0.516
inhA1674789c.588G>C0.544
inhA1674801c.600T>C0.559
inhA1674822c.621C>G0.547
inhA1674828c.627G>A0.573
inhA1674846p.Ile215Met0.625
inhA1674855c.654C>G0.583
inhA1674864c.663C>T0.562
inhA1674870c.669T>C0.559
inhA1674879c.678T>C0.531
inhA1674903c.702T>C0.559
inhA1674904p.Ala235Pro0.559
inhA1674909c.708G>A0.533
inhA1674942c.741T>G0.469
inhA1674960c.759C>G0.426
inhA1674966c.765T>G0.357
inhA1674967p.Asp256Thr0.357
inhA1674987c.786C>T0.350
rpsA1833512c.-30AC>A0.457
rpsA1833517c.-25AC>A0.580
rpsA1833518c.-24C>A0.532
rpsA1833532c.-10A>C0.538
rpsA1833554p.Thr5Ala0.586
rpsA1833568c.27G>C0.705
rpsA1833589c.48A>T0.716
rpsA1833595c.54T>C0.701
rpsA1833661c.120A>G0.695
rpsA1833664c.123C>G0.107
rpsA1833667c.126C>G0.685
rpsA1833721c.180A>G0.604
rpsA1833724c.183C>G0.511
rpsA1833727c.186G>C0.565
rpsA1833742c.201A>G0.578
rpsA1833745c.204G>C0.583
rpsA1833748c.207C>G0.521
rpsA1833787c.246C>G0.527
rpsA1833790c.249T>C0.564
rpsA1833802c.261A>G0.556
rpsA1833811c.270G>T0.576
rpsA1833838c.297G>C0.607
rpsA1833841c.300C>G0.629
rpsA1833847c.306C>G0.644
rpsA1833856c.315A>G0.650
rpsA1833874c.333T>C0.565
rpsA1833928c.387G>C0.609
rpsA1833940c.399C>G0.500
rpsA1833971c.430C>T0.423
rpsA1833979c.438T>C0.559
rpsA1833991c.450C>G0.110
rpsA1833994c.453G>C0.108
rpsA1834000c.459G>C0.587
rpsA1834015c.474G>C0.116
rpsA1834021c.480C>T0.612
rpsA1834030c.489C>G0.594
rpsA1834099c.558C>G0.491
rpsA1834102c.561T>C0.526
rpsA1834105c.564C>G0.545
rpsA1834108c.567C>G0.475
rpsA1834123c.582C>G0.610
rpsA1834150c.609G>C0.471
rpsA1834153c.612T>C0.469
rpsA1834154p.Asn205Gln0.469
rpsA1834157c.616T>C0.484
rpsA1834162c.621A>G0.429
rpsA1834165c.624A>G0.444
rpsA1834169p.Thr210Ala0.457
rpsA1834177c.636A>C1.000
rpsA1834183c.642T>C0.116
rpsA1834189c.648G>C0.571
rpsA1834195c.654G>C0.605
rpsA1834210c.669C>T0.638
rpsA1834222c.681T>C0.673
rpsA1834231c.690T>C0.698
rpsA1834234c.693G>C0.556
rpsA1834240c.699T>C0.125
rpsA1834249c.708T>C0.673
rpsA1834261c.720A>G0.583
rpsA1834262c.721T>A0.574
rpsA1834294c.753G>C0.113
rpsA1834303c.762T>C0.609
rpsA1834306c.765T>C0.672
rpsA1834333c.792C>T0.521
rpsA1834348c.807T>C0.640
rpsA1834366c.825A>G0.613
rpsA1834375c.834G>C0.107
rpsA1834396c.855G>C0.493
rpsA1834411c.870T>C0.620
rpsA1834417c.876G>C0.616
rpsA1834423c.882G>C0.623
rpsA1834435c.894G>C0.640
rpsA1834451c.910T>C0.659
rpsA1834465c.924T>C0.707
rpsA1834468c.927A>G0.693
rpsA1834489c.948T>C0.743
rpsA1834498c.957C>T0.136
rpsA1834510c.969C>T0.613
rpsA1834513c.972C>G0.581
rpsA1834528c.987T>C0.739
rpsA1834540c.999G>C0.603
rpsA1834546c.1005T>C0.716
rpsA1834555c.1014T>C0.119
rpsA1834573c.1032G>C0.131
rpsA1834609c.1068T>C0.655
rpsA1834633c.1092A>G0.636
rpsA1834639c.1098T>C0.636
rpsA1834654p.Glu371Asp0.586
rpsA1834684c.1143C>T0.548
rpsA1834690c.1149T>C0.600
rpsA1834732c.1191T>C0.615
rpsA1834733p.Ala398Ser0.547
rpsA1834738c.1197A>G0.544
rpsA1834753c.1212T>C0.609
rpsA1834765p.Glu408Asp0.618
rpsA1834775p.Ala412Thr0.569
rpsA1834780c.1239A>G0.652
rpsA1834786c.1245A>G0.646
rpsA1834789c.1248T>C0.656
rpsA1834792c.1251G>C0.650
rpsA1834849c.1308C>G0.542
rpsA1834852c.1311C>G0.596
tlyA1917940p.Val1Met0.404
tlyA1917943p.Ala2Ser0.404
tlyA1917951c.12T>C0.517
tlyA1917972c.33A>G1.000
tlyA1917975c.36C>G0.484
tlyA1917981c.42G>C0.530
tlyA1917990c.51G>C0.477
tlyA1917993c.54A>G0.477
tlyA1917996c.57A>G0.537
tlyA1918002c.63A>G0.563
tlyA1918036p.Arg33Ser0.536
tlyA1918048p.Leu37Met0.441
tlyA1918057p.Val40Arg0.295
tlyA1918065c.126G>C0.214
tlyA1918067p.Ala43Gly0.262
tlyA1918077c.138G>C0.211
tlyA1918078p.Ser47Ala0.216
tlyA1918082p.Asp48Val0.216
tlyA1918087p.Thr50Ala0.216
tlyA1918092c.153G>C0.205
tlyA1918103p.Val55Ala0.189
tlyA1918111p.Ser58Gly0.167
tlyA1918121p.Ala61Gly0.167
tlyA1918128c.189A>C0.188
tlyA1918137c.198A>C0.171
katG2154724p.Arg463Leu1.000
katG2155113c.999G>C0.130
katG2155626c.486C>G0.286
katG2155632c.480T>G0.323
katG2155637p.Leu159Ile0.344
katG2155641p.Lys157Asn0.342
katG2155661p.Val151Ile0.341
katG2155677c.435G>C0.333
katG2155680c.432C>G0.375
katG2155691c.421A>G0.396
katG2155695c.417G>C0.370
katG2155704c.408G>C0.370
katG2155716c.396A>C0.386
katG2155722c.390C>G0.375
katG2155728c.384C>G0.354
katG2155742p.Gly124Gln0.310
katG2155743c.369C>G0.310
katG2155782c.330G>C0.172
katG2155785c.327A>G0.143
katG2156069p.Ala15Pro0.933
pncA2288841p.Ala134Asp0.905
kasA2518121p.Gln3Lys0.194
kasA2518132c.18C>T0.281
kasA2518138c.24T>C0.257
kasA2518146p.Phe11Tyr0.447
kasA2518162c.48G>A0.465
kasA2518174c.60A>G0.535
kasA2518190p.Ser26Ala0.511
kasA2518199p.Ile29Val0.417
kasA2518220c.106C>T0.500
kasA2518234c.120G>A0.467
kasA2518248p.Ala45Val0.415
kasA2518261p.Glu49Asp0.342
kasA2518263p.Phe50Tyr0.324
kasA2518265p.Val51Ile0.324
kasA2518413p.Ser100Asn0.125
kasA2518421p.Val103Leu0.250
kasA2518429c.315A>C0.343
kasA2518439p.Ala109Ser0.371
kasA2518444c.330T>C0.371
kasA2518447c.333T>G0.389
kasA2518459c.345T>C0.412
kasA2518462c.348A>C0.487
kasA2518468c.354A>C0.500
kasA2518474c.360G>A0.455
kasA2518480c.366T>C0.562
kasA2518483c.369C>G0.510
kasA2518504c.390T>C0.619
kasA2518506p.Ala131Glu0.619
kasA2518519c.405G>C0.671
kasA2518528c.414C>G0.675
kasA2518540c.426T>C0.690
kasA2518561c.447T>C0.691
kasA2518567c.453G>C0.600
kasA2518570c.456G>C0.600
kasA2518574p.Ile154Val0.657
kasA2518579c.465T>C0.568
kasA2518588c.474T>C0.627
kasA2518591c.477G>C0.640
kasA2518609p.Met165Ile0.634
kasA2518624c.510C>G0.600
kasA2518639c.525G>C0.536
kasA2518642c.528A>G0.140
kasA2518651c.537C>G0.148
kasA2518657c.543G>C0.517
kasA2518663c.549T>C0.127
kasA2518671p.Val186Ala0.131
kasA2518678c.564C>T0.632
kasA2518684c.570C>G0.524
kasA2518688p.Val192Phe0.127
kasA2518696c.582C>G0.500
kasA2518702c.588C>T0.500
kasA2518705c.591T>C0.508
kasA2518711c.597A>G0.677
kasA2518714c.600A>C0.623
kasA2518732c.618C>G0.554
kasA2518744c.630C>T0.603
kasA2518747c.633C>G0.709
kasA2518768c.654C>T0.698
kasA2518777c.663C>T0.682
kasA2518783c.669T>C0.659
kasA2518789c.675G>C0.630
kasA2518792c.678C>A0.562
kasA2518795c.681C>G0.637
kasA2518801c.687G>C0.581
kasA2518825c.711T>C0.646
kasA2518864c.750G>C0.577
kasA2518879c.765A>G0.533
kasA2518885c.771T>C0.509
kasA2518898c.784T>C0.471
kasA2518906c.792A>G0.462
kasA2518910p.Leu266Met0.453
kasA2518921c.807T>C0.440
kasA2518936c.822C>G0.439
kasA2518939c.825T>C0.385
kasA2518942c.828T>C0.385
kasA2518951c.837G>C0.325
kasA2518954c.840C>G0.308
kasA2518963c.849T>C0.275
kasA2518969c.855T>G0.250
kasA2518975c.861C>G0.250
kasA2518979c.865A>C0.161
kasA2519050c.936C>G0.396
kasA2519053c.939G>C0.404
kasA2519056c.942G>C0.420
kasA2519062c.948T>G0.444
kasA2519068c.954C>T0.434
kasA2519072p.Ala320Thr0.426
kasA2519107c.993T>C0.517
kasA2519108p.Asp332Gln0.517
kasA2519116c.1002C>G0.508
kasA2519122c.1008G>C0.516
kasA2519137c.1023T>G0.554
kasA2519158c.1044C>T0.468
kasA2519167c.1053T>G0.448
kasA2519173c.1059C>G0.417
kasA2519196p.Thr361Ser0.352
kasA2519215c.1101C>T0.243
kasA2519218c.1104G>A0.194
kasA2519221c.1107G>C0.189
kasA2519227c.1113G>C0.184
kasA2519230c.1116C>T0.189
kasA2519236c.1122G>A0.233
kasA2519239c.1125A>C0.258
kasA2519245c.1131T>C0.206
kasA2519263c.1149C>T0.125
kasA2519266c.1152C>T0.129
kasA2519272c.1158C>G0.125
ahpC2726198c.6A>T0.286
ahpC2726204c.12A>G0.323
ahpC2726210c.18T>C0.324
ahpC2726216c.24T>C0.314
ahpC2726219c.27A>G0.333
ahpC2726232p.Gln14Glu0.375
ahpC2726243c.51T>G0.406
ahpC2726244c.52C>T0.406
ahpC2726251p.Gly20Ala0.406
ahpC2726255c.63T>C0.457
ahpC2726258c.66C>T0.457
ahpC2726303c.111T>C0.468
ahpC2726311p.Ser40Asn0.359
ahpC2726315p.Asp41Glu0.368
ahpC2726318p.Glu42Asp0.389
ahpC2726322p.Pro44Ala0.400
ahpC2726330c.138G>A0.400
ahpC2726336c.144G>C0.389
ahpC2726348c.156T>C0.394
ahpC2726357c.165A>G0.375
ahpC2726366c.174G>C0.407
ahpC2726378c.186T>G0.400
ahpC2726387c.195C>T0.318
ahpC2726390c.198G>C0.286
ahpC2726393c.201G>C0.286
ahpC2726397p.Ser69Gly0.286
ahpC2726408c.216T>C0.176
ahpC2726493p.Asn101Glu0.143
ahpC2726506p.Thr105Lys0.133
ahpC2726528c.336C>G0.217
ahpC2726540c.348C>G0.227
ahpC2726543c.351A>G0.217
ahpC2726546c.354C>G0.217
ahpC2726551p.Gln120Leu0.208
ahpC2726556p.Ala122Thr0.192
ahpC2726561c.369T>C0.167
ahpC2726564c.372C>G0.250
ahpC2726591c.399C>G0.482
ahpC2726593p.Val134Ala0.482
ahpC2726600c.408T>C0.492
ahpC2726601p.Ile137Leu0.492
ahpC2726638p.Ala149Val0.606
ahpC2726645c.453C>G0.618
ahpC2726657c.465A>C0.586
ahpC2726669p.Asp159Glu0.554
ahpC2726672c.480G>A0.556
ahpC2726675c.483A>G0.558
ahpC2726681c.489A>C0.529
ahpC2726687c.495C>G0.519
ahpC2726693c.501C>G0.471
ahpC2726696c.504C>G0.471
ahpC2726709c.517C>T0.489
ahpC2726717c.525A>G0.512
ahpC2726747c.555A>C0.343
folC2746365p.Leu412Val0.250
folC2746375c.1224C>G0.293
folC2746390c.1209C>G0.304
folC2746393c.1206G>C0.298
folC2746401p.Ser400Ala0.304
folC2746402c.1197A>G0.298
folC2746416p.Glu395Gln0.304
folC2746420c.1179T>G0.304
folC2746426c.1173C>G0.293
folC2746438c.1161C>G0.321
folC2746451p.Gly383Ala0.340
folC2746471c.1128G>T0.327
folC2746478p.Phe374Tyr0.327
folC2746480c.1119T>G0.326
folC2747026c.573G>C0.133
folC2747032c.567T>G0.229
folC2747059c.540A>G0.316
folC2747062c.537T>C0.350
folC2747065c.534G>A0.293
folC2747071c.528G>C0.316
folC2747086c.513T>G0.300
folC2747089c.510C>G0.333
folC2747101c.498C>G0.279
folC2747107c.492C>G0.341
folC2747110c.489A>G0.333
folC2747113c.486G>C0.311
folC2747116c.483C>G0.298
folC2747134c.465G>C0.277
folC2747224c.375C>G0.312
folC2747239c.360A>G0.424
folC2747248c.351C>G0.444
folC2747264p.Gly112Ala0.525
folC2747266c.333G>A0.538
folC2747275c.324A>G0.628
folC2747289p.Pro104Ala0.646
folC2747290c.309T>C0.660
folC2747293c.306C>T0.660
folC2747302c.297T>C0.689
folC2747314c.285T>G0.656
folC2747317c.282G>C0.701
folC2747343p.Val86Ile0.577
folC2747355p.Val82Ile0.527
folC2747359c.240G>C0.507
folC2747362c.237C>G0.487
folC2747394p.Ile69Val0.464
folC2747395c.204A>G0.455
folC2747407c.192A>G0.326
folC2747415p.Arg62Cys0.297
folC2747419c.180G>C0.306
folC2747422c.177C>T0.350
folC2747425c.174G>A0.275
folC2747442c.157A>G0.250
folC2747467p.Asp44Glu0.195
ribD2986959p.Leu41Val0.148
ribD2986978p.Ser47Thr0.222
ribD2986983p.Leu49Val0.229
ribD2986997c.159T>C0.235
ribD2987001p.Val55Ser0.242
ribD2987005p.Asp56Gly0.258
ribD2987011p.Thr58Ser0.281
ribD2987026p.Ala63Gly0.562
ribD2987033c.195C>G0.583
ribD2987042c.204A>G0.583
ribD2987046p.Val70Ile0.560
ribD2987058c.220T>C0.560
ribD2987066c.228A>G0.583
ribD2987069c.231T>C0.583
ribD2987092p.Val85Ala0.538
ribD2987105c.267C>G0.490
ribD2987108c.270T>C0.490
thyX3067223c.723C>G0.324
thyX3067232c.714G>C0.392
thyX3067246p.Thr234Ala0.347
thyX3067249p.Thr233Ser0.400
thyX3067252p.Val232Ile0.416
thyX3067272p.Ala225Glu0.307
thyX3067274c.672G>C0.375
thyX3067277c.669G>C0.479
thyX3067281p.Val222Ala0.461
thyX3067284p.Ala221Gly0.391
thyX3067286c.660G>C0.346
thyX3067289c.657G>C0.346
thyX3067292c.654C>T0.342
thyX3067295c.651G>A0.337
thyX3067316c.630T>C0.604
thyX3067325c.621T>C0.552
thyX3067349c.597C>G0.602
thyX3067355c.591T>G0.637
thyX3067367c.579C>G0.647
thyX3067373c.573G>C0.595
thyX3067391c.555C>G0.590
thyX3067394c.552C>G0.590
thyX3067439c.507T>C0.643
thyX3067442c.504G>A0.625
thyX3067445c.501G>C0.670
thyX3067457c.489G>C0.645
thyX3067462c.484G>A0.613
thyX3067465p.Ile161Val0.600
thyX3067466c.480C>G0.511
thyX3067475c.471T>C0.643
thyX3067490c.456G>C0.557
thyX3067493c.453T>C0.646
thyX3067510c.436G>A0.592
thyX3067515p.Ser144Thr0.653
thyX3067531p.Ala139Ser0.597
thyX3067545p.Glu134Ala0.574
thyX3067549p.Thr133Ala0.545
thyX3067556p.His130Gln0.538
thyX3067559c.387G>C0.673
thyX3067565p.Asp127Glu0.618
thyX3067570p.Ala126Pro0.629
thyX3067577c.369C>T0.562
thyX3067602p.Arg115His0.606
thyX3067611p.Lys112Thr0.652
thyX3067619c.327T>G0.657
thyX3067631c.315G>C0.662
thyX3067634c.312G>C0.662
thyX3067637c.309C>T0.632
thyX3067652c.294A>G0.630
thyX3067661c.285G>C0.680
thyX3067685c.261T>G0.680
thyX3067693p.Ile85Leu0.681
thyX3067694c.252C>G0.686
thyX3067718c.228G>C0.754
thyX3067721c.225A>G0.739
thyX3067727c.219T>G0.754
thyX3067736c.210G>A0.699
thyX3067762p.Arg62Lys0.689
thyX3067765p.Leu61Ile0.689
thyX3067772c.174G>C0.609
thyX3067775c.171G>A0.588
thyX3067781c.165G>C0.722
thyX3067793c.153A>G0.635
thyX3067799c.147C>T0.635
thyX3067802c.144G>C0.743
thyX3067850c.96T>G0.627
thyX3067869p.Thr26Ser0.485
thyX3067874c.72G>C0.574
thyX3067877c.69C>G0.477
thyX3067883c.63G>C0.581
thyX3067886c.60T>G0.518
thyX3067889c.57G>C0.509
thyX3067898p.Asp16Glu0.628
thyX3067935p.Thr4Ile0.472
thyX3067951c.-6A>G0.420
thyA3073812c.660G>C0.200
thyA3073815c.657C>T0.205
thyA3073824c.648T>C0.200
thyA3073827c.645T>C0.204
thyA3073833c.639G>A0.167
thyA3073839c.633A>G0.283
thyA3073860c.612G>C0.296
thyA3073863c.609A>G0.315
thyA3073866c.606G>C0.327
thyA3073874p.Ile200Val0.340
thyA3073892c.580A>G0.347
thyA3073898p.Ala192Ser0.308
thyA3073917c.555G>C0.255
thyA3073920c.552G>C0.333
thyA3073925c.547A>G0.340
thyA3073929c.543A>G0.320
thyA3073941c.531G>A0.170
thyA3073953c.519A>G0.300
thyA3073956c.516C>G0.279
thyA3073959c.513A>G0.159
thyA3073977c.495T>C0.310
thyA3073983c.489G>C0.222
thyA3073989c.483A>G0.295
thyA3074001c.471G>A0.167
thyA3074004c.468A>G0.271
thyA3074010c.462G>C0.314
thyA3074028c.444C>G0.345
thyA3074031c.441A>G0.356
thyA3074037c.435G>C0.393
thyA3074053p.Arg140Gln0.377
thyA3074057p.Glu139Pro0.358
thyA3074061c.411T>C0.345
thyA3074079c.393C>G0.333
thyA3074097c.375G>C0.373
thyA3074102p.Asp124Asn0.379
thyA3074103c.369G>C0.345
thyA3074106c.366A>G0.411
thyA3074127c.345C>G0.439
thyA3074130c.342C>G0.414
thyA3074147p.Ile109Val0.415
thyA3074159p.Ser105Thr0.317
thyA3074160c.312T>C0.350
thyA3074165p.Ala103Thr0.350
thyA3074172c.300C>G0.409
thyA3074175c.297T>C0.372
thyA3074181c.291T>C0.510
thyA3074187c.285A>G0.490
thyA3074205p.Glu89Asp0.521
thyA3074214c.258A>G0.543
thyA3074244c.228T>C0.510
thyA3074263p.Gly70Ala0.432
thyA3074267p.Ile69Val0.413
thyA3074268c.204A>G0.413
thyA3074285c.187A>G0.400
thyA3074286c.186A>G0.378
thyA3074297c.175G>A0.171
thyA3074301c.171G>A0.118
thyA3074360c.112C>A0.442
thyA3074372p.Met34Leu0.462
thyA3074377p.Gln32Arg0.462
thyA3074391c.81G>T0.514
thyA3074397c.75T>C0.515
thyA3074412c.60G>A0.516
thyA3074423p.Pro17Ala0.235
ald3086788c.-32T>C1.000
ald3087278p.Gln153His0.150
ald3087281c.462G>C0.136
ald3087290c.471T>G0.150
ald3087308c.489G>C0.125
ald3087318p.Glu167Lys0.148
ald3087323c.504G>C0.143
ald3087332c.513C>G0.156
ald3087344c.525C>G0.152
ald3087368c.549A>C0.161
ald3087375p.Ile186Val0.167
ald3087672p.His285Asp0.231
ald3087680c.861G>C0.231
ald3087704c.885T>C0.244
ald3087716c.897G>C0.191
ald3087726p.Ala303Ser0.180
ald3087729p.Ser304Ala0.176
ald3087737c.918G>C0.180
ald3087749c.930C>G0.167
ald3087750p.Tyr311Val0.184
ald3087761c.942C>G0.190
ald3087770c.951G>C0.178
ald3087787p.Glu323Ala0.128
fbiA3640291c.-252T>C0.158
fbiA3640307c.-236C>A0.158
fbiA3640347c.-196A>G0.484
fbiA3640349c.-194A>G0.323
fbiA3640350c.-193C>T0.323
fbiA3640365c.-178C>G0.500
fbiA3640378c.-165A>T0.152
fbiA3640820p.Val93Ala0.143
fbiA3640827c.285T>C0.250
fbiA3640830c.288C>G0.200
fbiA3640839c.297C>G0.282
fbiA3640850p.Glu103Gly0.314
fbiA3640857c.315G>C0.297
fbiA3640866c.324T>C0.205
fbiA3640871p.Ala110Gly0.216
fbiA3640878c.336T>C0.306
fbiA3640899c.357G>C0.195
fbiA3640900p.Gln120Asn0.262
fbiA3640914c.372C>G0.268
fbiA3640930p.Glu130Thr0.211
fbiA3640935c.393C>G0.211
fbiA3640938c.396A>G0.211
fbiA3640944c.402T>C0.216
alr3840944c.477A>G0.259
alr3840947c.474C>G0.259
alr3840959c.462C>G0.350
alr3840968c.453C>G0.391
alr3840980c.441C>G0.351
alr3840989c.432C>G0.356
alr3840994p.His143Asp0.361
alr3840997c.424C>G0.370
alr3841001c.420T>C0.370
alr3841010c.411T>C0.403
alr3841018p.Leu135Glu0.408
alr3841022c.399G>C0.403
alr3841028c.393C>G0.421
alr3841033p.Val130Ile0.432
alr3841037c.384C>G0.466
alr3841059p.Gly121Ala0.494
alr3841069p.Ile118Phe0.512
alr3841079c.342A>G0.479
alr3841100c.321T>C0.345
alr3841105p.Thr106Arg0.308
alr3841108p.Ile105Val0.302
alr3841112c.309A>G0.302
alr3841115c.306A>G0.308
alr3841127c.294T>C0.356
alr3841654c.-234A>C0.200
alr3841662c.-242A>G0.250
alr3841663c.-243G>A0.276
panD4044057c.225G>T0.429
panD4044072c.210G>C0.529
panD4044075c.207A>G0.581
panD4044081c.201A>G0.593
panD4044084c.198A>G0.567
panD4044105c.177C>G0.583
panD4044117c.165C>G0.583
panD4044120c.162T>G0.676
panD4044123c.159A>G0.676
panD4044126c.156A>G0.500
panD4044138c.144A>G0.619
panD4044141c.141G>C0.119
panD4044144c.138G>A0.122
panD4044150c.132T>C0.625
panD4044156c.126T>C0.133
panD4044162c.120T>C0.136
panD4044165c.117C>G0.439
panD4044174c.108G>C0.500
panD4044177c.105G>C0.400
panD4044180p.Asp34Glu0.150
panD4044188c.94A>G0.469
panD4044189c.93G>A0.484
panD4044195c.87A>G0.500
panD4044213c.69G>C0.161
panD4044225c.57G>A0.241
panD4044240c.42C>G0.200
panD4044264c.18C>G0.217
panD4044270c.12C>G0.217
embC4240033c.171G>C0.158
embC4240036c.174A>G0.158
embC4240037c.175T>C0.158
embC4240042c.180C>T0.167
embC4240048c.186C>G0.143
embC4240069c.207T>C0.160
embC4240078c.216A>G0.212
embC4240081c.219G>C0.270
embC4240087c.225T>C0.263
embC4240090c.228C>T0.310
embC4240105c.243C>T0.240
embC4240120c.258C>G0.104
embC4240123c.261C>G0.347
embC4240126c.264C>T0.333
embC4240141c.279A>G0.333
embC4240145p.Ala95Thr0.240
embC4240151p.Ser97Pro0.143
embC4240154p.Gln98Gly0.261
embC4240160p.Thr100Ala0.348
embC4240178c.316T>C0.279
embC4240183c.321A>G0.300
embC4240204c.342T>C0.318
embC4240216c.354T>C0.147
embC4240444c.582C>G0.300
embC4240459c.597G>C0.290
embC4240462c.600G>C0.290
embC4240471c.609C>T0.273
embC4240474c.612G>C0.273
embC4240475p.Ala205Ser0.281
embC4240484p.Ala208Thr0.300
embC4240489c.627A>G0.300
embC4240492c.630G>C0.300
embC4240495c.633T>G0.300
embC4240505p.Ser215Ala0.300
embC4240512p.Ser217Thr0.310
embC4240516c.654G>C0.333
embC4240519c.657T>C0.346
embC4240543c.681G>C0.321
embC4240558c.696C>G0.276
embC4240561c.699C>G0.286
embC4240630c.768C>A0.227
embC4240632p.Met257Thr0.273
embC4240642c.780G>C0.464
embC4240645c.783G>C0.414
embC4240654c.792C>G0.516
embC4240660c.798C>G0.533
embC4240669c.807G>C0.500
embC4240671p.Thr270Ile0.531
embC4240677p.Gly272Ala0.515
embC4240685p.Thr275Ala0.650
embC4240693c.831T>G0.636
embC4240699c.837C>G0.636
embC4240726c.864G>C0.672
embC4240780c.918T>C0.657
embC4240783c.921G>C0.662
embC4240789c.927T>C0.653
embC4240819c.957A>G0.557
embC4240828c.966G>A0.487
embC4240831c.969T>G0.514
embC4240867c.1005T>C0.354
embC4240870c.1008T>C0.283
embC4240873c.1011C>G0.289
embC4240879c.1017G>C0.317
embC4240880p.Ala340Thr0.310
embC4240885c.1023T>C0.366
embC4240897c.1035C>G0.351
embC4240898c.1036C>T0.361
embC4240903c.1041C>G0.297
embC4240911p.Ala350Val0.306
embC4240921c.1059C>G0.290
embC4240924c.1062C>G0.300
embC4240936c.1074A>G0.185
embC4240990c.1128A>G0.174
embC4240996c.1134G>C0.429
embC4241002c.1140G>C0.500
embC4241013p.Met384Thr0.551
embC4241017c.1155T>C0.560
embC4241023c.1161T>G0.577
embC4241032c.1170G>C0.600
embC4241038c.1176G>C0.600
embC4241047c.1185C>G0.577
embC4241050c.1188T>G0.577
embC4241053c.1191G>C0.589
embC4241089c.1227C>G0.633
embC4241095c.1233C>T0.667
embC4241107c.1245G>C0.682
embC4241140c.1278A>G0.744
embC4241146c.1284C>G0.709
embC4241158c.1296T>C0.603
embC4241161c.1299C>G0.579
embC4241162c.1300T>C0.632
embC4241170c.1308G>C0.589
embC4241173c.1311C>T0.579
embC4241179c.1317G>A0.589
embC4241203c.1341T>C0.543
embC4241206c.1344G>C0.543
embC4241218c.1356G>C0.468
embC4241230c.1368A>G0.419
embC4241233c.1371G>C0.405
embC4241351p.Ile497Val0.441
embC4241361p.Asn500Thr0.529
embC4241363p.Leu501Met0.543
embC4241374c.1512T>G0.632
embC4241380c.1518A>C0.632
embC4241383c.1521G>C0.585
embC4241394p.Lys511Ser0.608
embC4241449c.1587C>G0.590
embC4241453p.Ile531Val0.667
embC4241479c.1617C>G0.528
embC4241480c.1618T>C0.585
embC4241488c.1626G>C0.528
embC4241496p.Ala545Gly0.455
embC4241500c.1638A>C0.462
embC4241501p.Ser547Thr0.462
embC4241506c.1644G>C0.442
embC4241518c.1656A>G0.450
embC4241521c.1659T>C0.447
embC4241530c.1668C>G0.395
embC4241536c.1674A>G0.371
embC4241539c.1677T>C0.353
embC4241545c.1683T>C0.364
embC4241548c.1686T>C0.379
embC4241551c.1689A>G0.414
embC4241567p.Ile569Val0.429
embC4241572c.1710C>G0.310
embC4241578c.1716G>C0.259
embC4241584c.1722T>C0.240
embC4241587c.1725C>G0.240
embC4241591p.Leu577Val0.240
embC4241611c.1749G>C0.207
embC4241614c.1752A>C0.214
embC4241626c.1764T>C0.214
embC4241635c.1773G>C0.214
embC4241644c.1782G>C0.207
embC4241648c.1786T>C0.200
embC4241657p.Ser599Pro0.172
embC4241665c.1803G>C0.161
embC4241671c.1809T>C0.156
embC4242643c.2781C>T1.000
embC4242689p.Val943Ile0.431
embC4242710p.Gln950Glu0.475
embC4242715c.2853T>C0.492
embC4242742c.2880C>G0.542
embC4242748c.2886A>G0.525
embC4242754c.2892G>C0.562
embC4242764p.Val968Leu0.623
embC4242772c.2910G>C0.639
embC4242779p.Asn973Asp0.625
embC4242791p.Ala977Ser0.585
embC4242796c.2934G>C0.574
embC4242799c.2937T>C0.564
embC4242802c.2940G>C0.534
embC4242820c.2958G>C0.540
embC4242823c.2961G>C0.524
embC4242832c.2970A>C0.536
embC4242838c.2976C>G0.492
embC4242841c.2979C>T0.473
embC4242847c.2985C>A0.491
embC4242859c.2997C>T0.491
embC4242862c.3000A>G0.491
embC4242863p.Tyr1001Asn0.491
embC4242883c.3021C>G0.462
embC4242892c.3030G>C0.453
embC4242901c.3039G>C0.375
embC4242919c.3057A>G0.333
embC4242928c.3066A>G0.325
embC4242931c.3069G>C0.282
embC4242940c.3078T>C0.212
embC4242941p.His1027Asn0.212
embC4242946c.3084T>C0.226
embC4242952c.3090T>C0.226
embC4242959c.3097C>T0.214
embC4242965p.Ile1035Val0.222
embA4243460c.228C>T1.000
embA4244447c.1215G>C0.213
embA4244462c.1230A>G0.286
embA4244478p.Thr416Leu0.339
embA4244483c.1251T>G0.339
embA4244485p.Thr418Ser0.333
embA4244498c.1266A>G0.413
embA4244507c.1275G>T0.422
embA4244508c.1276T>C0.422
embA4244516c.1284G>C0.448
embA4244517p.Leu429Val0.448
embA4244523p.Pro431Ala0.480
embA4244534c.1302T>C0.519
embA4244537c.1305T>G0.519
embA4244543c.1311C>G0.532
embA4244547p.Ile439Val0.558
embA4244557p.Arg442Thr0.570
embA4244582c.1350T>C0.513
embA4244585c.1353A>G0.500
embA4244611p.Ala460Gly0.380
embA4244616p.Ala462Ser0.375
embA4244619c.1387T>C0.375
embA4244625p.Leu465Val0.360
embA4244631p.Thr467Leu0.383
embA4244645c.1413T>C0.364
embA4244648c.1416G>C0.325
embA4244649p.Asp473Ser0.325
embA4244802c.1570T>C0.200
embA4244808p.Phe526Leu0.207
embA4244823p.Val531Met0.214
embA4244829p.Phe533Val0.194
embA4244832p.Val534Ile0.188
embA4244846c.1614C>G0.207
embA4244849c.1617C>G0.200
embA4244856p.Ala542Pro0.207
embA4244862p.Leu544Val0.200
embA4245041c.1809C>G0.488
embA4245044c.1812G>C0.500
embA4245053c.1821G>C0.568
embA4245060c.1828T>C0.595
embA4245083c.1851A>C0.660
embA4245089c.1857G>C0.625
embA4245101c.1869G>C0.683
embA4245137c.1905T>C0.768
embA4245146c.1914G>A0.677
embA4245149c.1917C>G0.769
embA4245153p.Ile641Val0.682
embA4245182c.1950T>C0.731
embA4245189c.1957C>T0.712
embA4245198p.Leu656Ile0.606
embA4245207c.1975T>C0.697
embA4245215c.1983A>C0.683
embA4245222p.Tyr664Gln0.667
embA4245248c.2016G>C0.604
embA4245257c.2025A>G0.531
embA4245263c.2031A>G0.574
embA4245282p.Ile684Val0.364
embA4245285c.2053T>C0.353
embA4245290c.2058C>G0.333
embA4245293c.2061T>G0.333
embA4245296c.2064G>C0.324
embA4245299c.2067A>G0.314
embA4245652p.Thr807Ser0.150
embA4245659c.2427C>G0.472
embA4245665c.2433C>A0.535
embA4245674c.2442A>C0.596
embA4245677c.2445G>C0.571
embA4245693p.Ile821Val0.648
embA4245701c.2469G>C0.617
embA4245704c.2472G>C0.609
embA4245725c.2493A>G0.667
embA4245726c.2494T>C0.672
embA4245737c.2505A>C0.662
embA4245740c.2508T>C0.662
embA4245764c.2532G>C0.662
embA4245772p.Asn847Thr0.618
embA4245785c.2553G>C0.594
embA4245807c.2575T>C0.364
embA4245812c.2580G>C0.357
embA4245813p.Pro861Ala0.357
embA4245820p.Ser863Thr0.364
embA4245824c.2592G>C0.326
embA4245833c.2601G>C0.341
embA4245842c.2610G>C0.349
embA4245845c.2613T>C0.349
embA4245851c.2619G>C0.349
embA4245860c.2628C>G0.295
embA4246184c.2952A>C0.211
embA4246196c.2964C>G0.250
embA4246205c.2973A>G0.222
embA4246211c.2979T>C0.200
embA4246217c.2985G>A0.190
embA4246220c.2988T>C0.200
embA4246223c.2991C>T0.238
embA4246227p.Ile999Val0.227
embA4246235c.3003G>A0.417
embA4246242p.Gln1004Gly0.320
embA4246250c.3018G>C0.393
embA4246256c.3024G>T0.367
embA4246259c.3027G>C0.500
embA4246264p.His1011Arg0.424
embA4246292c.3060A>G0.545
embA4246305p.Ser1025Glu0.441
embA4246308p.Thr1026Ala0.441
embA4246316c.3084T>G0.364
embA4246319c.3087G>C0.333
embA4246329p.Thr1033Ala0.333
embA4246349c.3117C>G0.343
embA4246359p.Ala1043Ser0.290
embA4246367c.3135C>T0.300
embA4246373c.3141T>C0.267
embA4246376c.3144G>C0.267
embA4246379c.3147C>T0.267
embA4246400c.3168G>C0.152
embB4246548p.Pro12Gln0.130
embB4247348p.Thr279Ala0.138
embB4247355p.Ala281Val0.143
embB4247357p.Val282Thr0.143
embB4247362c.849G>C0.129
embB4247365c.852A>C0.226
embB4247371c.858C>G0.257
embB4247375p.Leu288Val0.139
embB4247380c.867C>G0.150
embB4247386c.873T>C0.385
embB4247389c.876C>G0.400
embB4247395c.882C>G0.444
embB4247401c.888T>C0.458
embB4247407c.894G>C0.431
embB4247410c.897C>T0.288
embB4247425c.912G>C0.333
embB4247434c.921C>G0.333
embB4247437c.924A>G0.466
embB4247446c.933C>T0.357
embB4247464c.951C>G0.522
embB4247470c.957T>C0.529
embB4247491c.978G>C0.459
embB4247495p.Asp328Cys0.486
embB4247512c.999T>C0.487
embB4247529p.Leu339Pro0.137
embB4247539c.1026T>C0.400
embB4247554c.1041T>C0.393
embB4247566c.1053C>A0.382
embB4247572c.1059A>G0.351
embB4247579p.Ala356Phe0.231
embB4247587c.1074G>A0.240
embB4247603c.1090C>T0.239
embB4247611c.1098G>T0.186
embB4247614c.1101T>C0.200
embB4247629c.1116C>G0.226
embB4247632c.1119C>G0.194
embB4247638c.1125G>C0.143
embB4247683c.1170C>G0.375
embB4247692c.1179C>G0.441
embB4247716c.1203C>T0.515
embB4247722c.1209G>C0.529
embB4247725c.1212G>C0.500
embB4247729p.Gly406Pro0.562
embB4247746c.1233C>T0.660
embB4247761c.1248T>C0.630
embB4247773c.1260G>A0.644
embB4247776c.1263G>T0.695
embB4247797c.1284C>G0.672
embB4247800c.1287A>T0.656
embB4247803c.1290G>C0.642
embB4247815c.1302C>G0.667
embB4247819p.Val436Ile0.625
embB4247830c.1317A>G0.609
embB4247836c.1323A>G0.609
embB4247839c.1326G>C0.609
embB4247866c.1353G>C0.623
embB4247875c.1362G>C0.571
embB4247876c.1363C>T0.594
embB4247881c.1368G>C0.582
embB4247887c.1374C>T0.603
embB4247893c.1380C>T0.603
embB4247899p.Met462Ile0.620
embB4247905c.1392G>C0.627
embB4247909c.1396T>C0.627
embB4247914c.1401G>C0.620
embB4247932c.1419C>G0.629
embB4247940p.Leu476Trp0.634
embB4247945c.1432T>C0.642
embB4247951p.Ser480Ala0.672
embB4247956c.1443G>C0.672
embB4247965c.1452C>A0.652
embB4247974c.1461C>G0.652
embB4248007c.1494C>G0.597
embB4248011p.Ser500Arg0.567
embB4248014p.Thr501Ala0.576
embB4248035p.Val508Ile0.554
embB4248040c.1527C>G0.556
embB4248041p.Ala510Thr0.556
embB4248044p.Lys511Ala0.556
embB4248070c.1557T>C0.621
embB4248085c.1572T>C0.596
embB4248097c.1584C>G0.593
embB4248130c.1617G>C0.619
embB4248139c.1626C>G0.600
embB4248142c.1629T>C0.611
embB4248143c.1630T>C0.615
embB4248157c.1644A>G0.636
embB4248172c.1659G>C0.694
embB4248199c.1686A>G0.636
embB4248200p.Ile563Val0.636
embB4248205c.1692C>G0.667
embB4248206p.Ser565Gly0.659
embB4248220c.1707A>C0.696
embB4248232c.1719G>C0.113
embB4248233c.1720C>T0.113
embB4248253c.1740C>A0.119
embB4248266c.1753C>T0.128
embB4248304c.1791G>C0.600
embB4248316c.1803C>G0.663
embB4248319c.1806A>G0.650
embB4248325c.1812G>A0.561
embB4248343c.1830G>C0.543
embB4248350c.1837T>C0.563
embB4248355c.1842A>G0.536
embB4248358c.1845C>G0.536
embB4248361c.1848A>C0.508
embB4248362p.Ser617Ala0.516
embB4248373c.1860C>G0.571
embB4248382c.1869C>G0.582
embB4248386c.1873C>A0.577
embB4248407p.Leu632Val0.448
embB4248410p.Phe633Leu0.439
embB4248419p.Leu636Met0.464
embB4248425c.1912T>C0.510
embB4248430c.1917T>C0.510
embB4248432p.Trp640Phe0.510
embB4248457c.1944T>C0.633
embB4248472c.1959T>C0.581
embB4248475c.1962G>C0.565
embB4248504p.Asp664Gly0.580
embB4248508c.1995G>A0.542
embB4248512p.Thr667Ser0.532
embB4248535c.2022C>G0.395
embB4249369c.2856T>C0.400
embB4249375c.2862G>C0.415
embB4249381c.2868A>G0.409
embB4249384c.2871G>T0.438
embB4249417c.2904A>G0.596
embB4249423p.Asp970Glu0.618
embB4249424p.Leu971Met0.618
embB4249429c.2916C>T0.630
embB4249432c.2919A>G0.638
embB4249441c.2928A>G0.587
embB4249444c.2931T>C0.708
embB4249447c.2934G>C0.121
embB4249469p.Leu986Met0.700
embB4249486c.2973T>G0.676
embB4249498c.2985G>C0.658
embB4249521p.Ala1003Val0.630
embB4249525c.3012T>C0.596
embB4249529p.Ile1006Val0.558
embB4249532p.Ala1007Thr0.547
embB4249537c.3024A>G0.556
embB4249543c.3030G>C0.500
embB4249546c.3033G>A0.491
embB4249558c.3045A>C0.490
embB4249568p.Ser1019Thr0.500
embB4249573c.3060T>C0.475
embB4249580p.Leu1023Met0.368
embB4249594c.3081G>C0.367
embB4249606c.3093C>A0.182
ethA4327396c.78A>G0.452
ethA4327399p.Asp25Glu0.475
ethA4327423c.51G>C0.487
ethA4327435c.39T>G0.528
ethA4327438c.36A>G0.500
ethA4327452p.Val8Leu0.393
ethA4327453c.21A>G0.393
ethA4327459c.15G>A0.367
ethA4327468c.6G>A0.278
gid4407588c.615T>C1.000
gid4407927p.Glu92Asp1.000

Analysis pipeline specifications

TBProfiler Version: 2.1.1

AnalysisProgram
Mappingbwa
Variant CallingBCFtools


Log

Drug Details
The estimated accuracy of drug resistance predictions is:

Drug1Sensitivity (%)Specificity (%)
Isoniazid 92.8 (89.9-95.7)100 (100-100)
Rifampicin 96.2 (93.9-98.5)98.1 (96.8-99.4)
Ethambutal 88.7 (83.6-93.8)81.7 (77.6-85.8)
Pyrazinamide70.9 (62.4-79.4)93.9 (90.6-97.2)
Streptomycin87.1 (82.7-91.5)89.7 (86.0-93.4)
Ethionamide 73.6 (66.7-80.5)93.3 (89.6-97.0)
Moxifloxacin60.0 (29.6-90.4)68.7 (52.6-84.8)
Ofloxacin 85.5 (79.1-91.9)94.9 (91.8-98.0)
Amikacin 82.9 (74.4-91.4)98.3 (96.0-100)
Capreomycin 60.7 (50.6-70.8)90.7 (87.2-94.2)
Kanamycin 87.3 (81.3-93.3)93.4 (89.9-96.9)
Para-aminosalisylic acidNot determinedNot determined
Linezolid Not determinedNot determined
Clofazimine Not determinedNot determined
Bedaquiline Not determinedNot determined
Multi drug resistance91.2 (87.8-94.6)98.4 (97.2-99.6)
Extremely drug resistance75.9 (64.5-87.3)98.4 (97.3-99.5)

Lineages
Lineage2LocationStrainRD type
lineage1Indo-OceanicEAIRD239
lineage1.1Indo-OceanicEAI3;EAI4;EAI5;EAI6RD239
lineage1.1.1Indo-OceanicEAI4;EAI5RD239
lineage1.1.1.1Indo-OceanicEAI4;ZERORD239
lineage1.1.2Indo-OceanicEAI3;EAI5RD239
lineage1.1.3Indo-OceanicEAI6RD239
lineage1.2Indo-OceanicEAI1;EAI2RD239
lineage1.2.1Indo-OceanicEAI2RD239
lineage1.2.2Indo-OceanicEAI1RD239
lineage2East-AsianBeijingRD105
lineage2.1East-Asian (non-Beijing)NoneNone
lineage2.2East-Asian (Beijing)Beijing-RD207RD105;RD207
lineage2.2.2East-Asian (Beijing)Beijing-RD105/RD207RD105;RD207
lineage2.2.1East-Asian (Beijing)Beijing-RD181RD105;RD207;RD181
lineage2.2.1.2East-Asian (Beijing)Beijing-RD142RD105;RD207;RD181;RD142
lineage2.2.1.1East-Asian (Beijing)Beijing-RD150RD105;RD207;RD181;RD150
lineage3East-African-IndianCASRD750
lineage3.1East-African-IndianNon-CAS1-DelhiRD750
lineage3.1.1East-African-IndianCAS1-KiliRD750
lineage3.1.2East-African-IndianCAS;CAS2RD750
lineage3.1.2.1East-African-IndianCAS2RD750
lineage3.1.2.2East-African-IndianCASRD750
lineage4Euro-AmericanLAM;T;S;X;HNone
lineage4.1Euro-AmericanT;X;HNone
lineage4.1.2Euro-American (X-type)T;HNone
lineage4.1.2.1Euro-American (X-type)T1;H1RD182
lineage4.1.1Euro-American (X-type)X1;X2;X3None
lineage4.1.1.2Euro-American (X-type)X1None
lineage4.1.1.1Euro-American (X-type)X2RD183
lineage4.1.1.3Euro-American (Haarlem)X1;X3RD193
lineage4.2Euro-AmericanH;T;LAMNone
lineage4.2.2Euro-American (Ural)T;LAM7-TURNone
lineage4.2.2.1Euro-AmericanLAM7-TURNone
lineage4.2.1Euro-American (TUR)H3;H4None
lineage4.3Euro-American (LAM)mainly-LAMNone
lineage4.3.1Euro-American (LAM)LAM9None
lineage4.3.3Euro-American (LAM)LAM;TRD115
lineage4.3.4Euro-American (LAM)LAMRD174
lineage4.3.4.1Euro-American (LAM)LAM1;LAM2RD174
lineage4.3.4.2Euro-American (LAM)LAM1;LAM4;LAM11RD174
lineage4.3.4.2.1Euro-American (LAM)LAM11RD174
lineage4.3.2Euro-American (LAM)LAM3None
lineage4.3.2.1Euro-American (LAM)LAM3RD761
lineage4.4Euro-AmericanS;TNone
lineage4.4.2Euro-AmericanT1;T2None
lineage4.4.1Euro-American (S-type)S;TNone
lineage4.4.1.2Euro-AmericanT1None
lineage4.4.1.1Euro-AmericanS;OrphansNone
lineage4.5Euro-AmericanH;TRD122
lineage4.6Euro-AmericanT;LAMNone
lineage4.6.1Euro-American (Uganda)T2RD724
lineage4.6.1.1Euro-American T2-UgandaRD724
lineage4.6.1.2Euro-AmericanT2RD724
lineage4.6.2Euro-AmericanT;LAMRD726
lineage4.6.2.1Euro-AmericanT3RD726
lineage4.6.2.2Euro-American (Cameroon)LAM10-CAMRD726
lineage4.7Euro-American (mainly T)T1;T5None
lineage4.8Euro-American (mainly T)T1;T2;T3;T5RD219
lineage4.9Euro-American (H37Rv-like)T1None
lineage5West-Africa 1AFRI_2;AFRI_3RD711
lineage6West-Africa 2AFRI_1RD702
lineage7Lineage 7NoneNone
lineageBOVM. bovisBOV_1;BOV_2None

Citations
1. Coll F, et al. Rapid determination of anti-tuberculosis drug resistance from whole genome sequences. Genome Medicine (in press)
2. Coll F, et al. A robust SNP barcode for typing Mycobacterium tuberculosis complex strains. Nature Communications 2014.

Disclaimer
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