TB-Profiler result

Run: DRR034379

Summary

Run ID: DRR034379

Sample name:

Date: 31-03-2023 06:57:04

Number of reads: 812942

Percentage reads mapped: 99.77

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5424 p.Ala62Gly missense_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 764126 p.Thr253Ser missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518590 p.Gly159Val missense_variant 0.11
kasA 2518606 c.492G>C synonymous_variant 0.11
kasA 2518609 p.Met165Ile missense_variant 0.11
folC 2747325 p.Arg92Ser missense_variant 1.0
fbiD 3339593 p.His159Arg missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0