Run ID: DRR034386
Sample name:
Date: 31-03-2023 06:57:13
Number of reads: 481860
Percentage reads mapped: 99.66
Strain: lineage4.8
Drug-resistance: Sensitive
Drug | Resistance | Supporting mutations |
---|
Lineage | Family | Main Spoligotype | RDs | Frequency |
---|---|---|---|---|
lineage4 | Euro-American | LAM;T;S;X;H | None | 1.0 |
lineage4.8 | Euro-American (mainly T) | T1;T2;T3;T5 | RD219 | 1.0 |
Gene | Chromosome position | Mutation | Type | Estimated fraction | Drugs |
---|
Gene | Chromosome position | Mutation | Type | Estimated fraction |
---|---|---|---|---|
gyrB | 6092 | p.His285Asp | missense_variant | 1.0 |
gyrA | 7362 | p.Glu21Gln | missense_variant | 1.0 |
ccsA | 619830 | c.-60delT | upstream_gene_variant | 0.2 |
ccsA | 619986 | c.96G>A | synonymous_variant | 0.18 |
rpoB | 762595 | p.Leu930Gln | missense_variant | 0.14 |
rpoC | 763814 | p.Ser149Pro | missense_variant | 0.15 |
mmpL5 | 775639 | p.Ile948Val | missense_variant | 1.0 |
rpsL | 781395 | c.-165T>C | upstream_gene_variant | 1.0 |
fbiC | 1303783 | p.Gly285Arg | missense_variant | 1.0 |
fbiC | 1304412 | p.Asp494Glu | missense_variant | 0.22 |
Rv1258c | 1407052 | p.Gly97Ser | missense_variant | 0.12 |
rrs | 1471659 | n.-187C>T | upstream_gene_variant | 1.0 |
rrl | 1474001 | n.344C>T | non_coding_transcript_exon_variant | 1.0 |
fabG1 | 1673884 | p.Asn149Asp | missense_variant | 0.11 |
tlyA | 1917972 | c.33A>G | synonymous_variant | 1.0 |
ndh | 2101684 | p.Gln453His | missense_variant | 1.0 |
PPE35 | 2168149 | p.Pro822Ser | missense_variant | 1.0 |
PPE35 | 2169965 | p.Asn216Lys | missense_variant | 0.13 |
Rv1979c | 2223293 | c.-129A>G | upstream_gene_variant | 1.0 |
eis | 2715448 | c.-116A>T | upstream_gene_variant | 0.17 |
Rv2752c | 3064765 | p.Thr476Ile | missense_variant | 0.15 |
thyX | 3067583 | c.363C>A | synonymous_variant | 0.4 |
Rv3083 | 3448427 | c.-77C>A | upstream_gene_variant | 0.15 |
Rv3236c | 3612888 | p.Phe77Ile | missense_variant | 0.11 |
fbiA | 3640522 | c.-21C>G | upstream_gene_variant | 0.13 |
fbiA | 3641371 | p.Gly277Ser | missense_variant | 0.11 |
fbiB | 3641847 | p.Ala105Thr | missense_variant | 0.2 |
embC | 4242561 | p.Trp900* | stop_gained | 0.22 |
embA | 4242643 | c.-590C>T | upstream_gene_variant | 1.0 |
embA | 4243846 | p.Ala205Gly | missense_variant | 0.17 |
aftB | 4268469 | p.Leu123Gln | missense_variant | 0.14 |
whiB6 | 4338595 | c.-75delG | upstream_gene_variant | 1.0 |
gid | 4408060 | p.His48Pro | missense_variant | 1.0 |
Rv3083 | 3448507 | c.5_*1408del | frameshift_variant&stop_lost&splice_region_variant | 1.0 |