TB-Profiler result

Run: DRR034426
Summary

Run ID: DRR034426

Sample name:

Date: 31-03-2023 06:58:24

Number of reads: 825368

Percentage reads mapped: 99.79

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491170 p.Ala130Thr missense_variant 0.14
mshA 576680 p.Ile445Val missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
Rv1258c 1406522 c.819G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170066 p.Ala183Thr missense_variant 0.1
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
folC 2746161 p.Thr480Ala missense_variant 0.12
folC 2746770 p.Leu277Val missense_variant 0.1
fprA 3475293 p.Phe429Leu missense_variant 0.12
Rv3236c 3612442 c.675C>A synonymous_variant 0.1
embC 4242114 p.Leu751Pro missense_variant 0.1
embC 4242735 p.Ile958Asn missense_variant 0.11
whiB6 4338595 c.-75delG upstream_gene_variant 1.0