TB-Profiler result

Run: DRR034488
Summary

Run ID: DRR034488

Sample name:

Date: 31-03-2023 07:00:18

Number of reads: 654523

Percentage reads mapped: 99.42

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576750 p.Lys468Thr missense_variant 0.2
rpoC 766019 p.Val884Leu missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518264 c.150C>T synonymous_variant 0.1
eis 2715432 c.-100C>T upstream_gene_variant 0.15
eis 2715436 c.-104G>A upstream_gene_variant 0.15
eis 2715440 c.-108A>C upstream_gene_variant 0.15
eis 2715445 c.-113C>T upstream_gene_variant 0.15
eis 2715447 c.-115T>A upstream_gene_variant 0.15
eis 2715450 c.-118T>C upstream_gene_variant 0.15
eis 2715451 c.-119C>A upstream_gene_variant 0.15
eis 2715454 c.-122T>G upstream_gene_variant 0.15
eis 2715455 c.-123G>A upstream_gene_variant 0.15
eis 2715458 c.-126T>A upstream_gene_variant 0.15
eis 2715460 c.-128A>G upstream_gene_variant 0.15
eis 2715465 c.-133G>T upstream_gene_variant 0.15
eis 2715469 c.-137T>C upstream_gene_variant 0.15
eis 2715473 c.-141A>G upstream_gene_variant 0.15
folC 2746628 p.Asp324Val missense_variant 0.14
fbiD 3339273 c.156T>G synonymous_variant 0.16
aftB 4267375 p.Phe488Leu missense_variant 0.1
ethR 4327225 c.-324C>T upstream_gene_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0