TB-Profiler result

Run: ERR017790

Summary

Run ID: ERR017790

Sample name:

Date: 31-03-2023 07:56:18

Number of reads: 186225

Percentage reads mapped: 93.05

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4.9 Euro-American (H37Rv-like) T1 None 0.95
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8688 p.Ala463Ser missense_variant 0.67
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 763031 c.-339T>C upstream_gene_variant 0.67
mmpL5 776100 p.Thr794Ile missense_variant 0.8
mmpS5 779615 c.-710C>G upstream_gene_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715424 c.-92C>G upstream_gene_variant 0.67
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242822 p.Val987Gly missense_variant 0.5