TB-Profiler result

Run: ERR023245
Summary

Run ID: ERR023245

Sample name:

Date: 31-03-2023 07:58:44

Number of reads: 311301

Percentage reads mapped: 98.26

Strain:

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7423 p.Leu41Pro missense_variant 0.22
gyrA 7585 p.Ser95Thr missense_variant 0.9
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9596 c.2295G>T synonymous_variant 0.38
fgd1 491742 c.960T>C synonymous_variant 0.29
mshA 575679 p.Asn111Ser missense_variant 0.33
rpoB 760115 c.309C>T synonymous_variant 0.33
rpoC 763031 c.-339T>C upstream_gene_variant 0.5
rpoC 763531 c.162G>C synonymous_variant 0.29
rpoC 764181 p.Asp271Gly missense_variant 0.3
rpoC 764995 c.1626C>G synonymous_variant 0.57
rpoC 765704 p.Lys779Glu missense_variant 0.43
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.71
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
atpE 1460907 c.-138T>C upstream_gene_variant 0.4
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.43
PPE35 2168789 c.1824C>T synonymous_variant 0.33
PPE35 2169320 p.Leu431Phe missense_variant 0.2
Rv1979c 2223233 c.-69G>C upstream_gene_variant 0.43
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2517924 c.-191G>A upstream_gene_variant 0.18
kasA 2518076 c.-39C>T upstream_gene_variant 0.3
kasA 2518141 c.29dupG frameshift_variant 0.29
ahpC 2726043 c.-150C>T upstream_gene_variant 0.33
pepQ 2859381 c.1038C>G synonymous_variant 0.67
thyX 3067446 p.Ala167Val missense_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 0.86
fprA 3473996 c.-11_-10insA upstream_gene_variant 0.89
fprA 3474597 c.591C>A synonymous_variant 0.25
Rv3236c 3612832 c.285C>T synonymous_variant 0.22
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242803 p.Val981Leu missense_variant 0.33
embB 4247800 c.1287A>C synonymous_variant 0.4
ethR 4327909 p.Thr121Pro missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0