TB-Profiler result

Run: ERR023733
Summary

Run ID: ERR023733

Sample name:

Date: 31-03-2023 08:00:48

Number of reads: 971731

Percentage reads mapped: 93.8

Strain: lineage4.7

Drug-resistance: Other

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.7 Euro-American (mainly T) T1;T5 None 0.99
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
folC 2747381 p.Asn73Ser missense_variant 0.11 para-aminosalicylic_acid
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303174 p.Leu82Val missense_variant 0.36
fbiC 1305422 p.Ala831Val missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 0.95
rrl 1474294 n.637C>G non_coding_transcript_exon_variant 1.0
inhA 1674952 p.Pro251Ala missense_variant 0.5
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167686 p.Asn976Ser missense_variant 0.12
PPE35 2169862 p.Asn251His missense_variant 0.28
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
panD 4043878 c.403delC frameshift_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4249732 c.3219C>G synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0