TB-Profiler result

Run: ERR023753
Summary

Run ID: ERR023753

Sample name:

Date: 31-03-2023 08:05:42

Number of reads: 362713

Percentage reads mapped: 95.55

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9143 c.1842T>C synonymous_variant 0.43
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491742 c.960T>C synonymous_variant 0.18
mshA 575679 p.Asn111Ser missense_variant 0.5
rpoB 760115 c.309C>T synonymous_variant 0.5
rpoC 763031 c.-339T>C upstream_gene_variant 0.18
rpoC 763730 c.365delC frameshift_variant 0.29
rpoC 764995 c.1626C>G synonymous_variant 0.67
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.56
inhA 1674162 c.-40C>T upstream_gene_variant 0.18
rpsA 1834394 p.Arg285Trp missense_variant 0.21
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918721 p.His261Arg missense_variant 0.5
katG 2154724 p.Arg463Leu missense_variant 0.33
PPE35 2167926 p.Leu896Ser missense_variant 0.17
PPE35 2168815 p.Thr600Ala missense_variant 0.2
PPE35 2169320 p.Leu431Phe missense_variant 0.33
PPE35 2169783 p.Thr277Lys missense_variant 0.33
pncA 2289524 c.-283C>T upstream_gene_variant 0.33
kasA 2518076 c.-39C>T upstream_gene_variant 0.25
ahpC 2726338 p.Val49Gly missense_variant 0.33
thyA 3073868 p.Thr202Ala missense_variant 0.67
thyA 3074657 c.-186C>G upstream_gene_variant 0.29
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
clpC1 4038287 c.2418C>T synonymous_variant 0.5
clpC1 4039932 p.Gly258Val missense_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246280 c.-234G>T upstream_gene_variant 0.25
ubiA 4269361 p.Leu158Ser missense_variant 0.12
ubiA 4269387 p.Glu149Asp missense_variant 0.13
ubiA 4269864 c.-31C>G upstream_gene_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
whiB6 4338603 c.-82C>T upstream_gene_variant 0.23
gid 4407644 p.Arg187Trp missense_variant 0.6
gid 4408156 p.Leu16Arg missense_variant 0.5