TB-Profiler result

Run: ERR024336
Summary

Run ID: ERR024336

Sample name:

Date: 31-03-2023 08:09:14

Number of reads: 350855

Percentage reads mapped: 97.06

Strain: lineage4.3.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3.2 Euro-American (LAM) LAM3 None 0.79
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 766139 p.Thr924Pro missense_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1472337 n.492C>T non_coding_transcript_exon_variant 0.83
inhA 1674952 p.Pro251Ala missense_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918034 p.Val32Gly missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289115 p.His43Tyr missense_variant 0.5
ahpC 2726338 p.Val49Gly missense_variant 0.29
Rv2752c 3064570 p.Val541Gly missense_variant 0.33
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074657 c.-186C>G upstream_gene_variant 0.25
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fbiD 3339273 c.156T>G synonymous_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
Rv3236c 3612361 c.756C>T synonymous_variant 0.67
fbiB 3641633 c.99C>T synonymous_variant 0.17
rpoA 3877665 c.843C>T synonymous_variant 0.2
clpC1 4038287 c.2418C>T synonymous_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>G upstream_gene_variant 0.4
embA 4244846 c.1614C>G synonymous_variant 0.22
embB 4248706 c.2193G>A synonymous_variant 0.5
whiB6 4338377 p.Ala49Thr missense_variant 0.25
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407644 p.Arg187Trp missense_variant 0.44
gid 4408156 p.Leu16Arg missense_variant 1.0