TB-Profiler result

Run: ERR025885
Summary

Run ID: ERR025885

Sample name:

Date: 31-03-2023 08:18:54

Number of reads: 294798

Percentage reads mapped: 47.3

Strain: lineage4.1.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.08
lineage4.1.2 Euro-American T;H None 0.12
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 759620 c.-187A>C upstream_gene_variant 0.75
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 778134 p.Leu116Arg missense_variant 0.5
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1416439 c.909G>T synonymous_variant 0.33
rrs 1473030 n.1185G>A non_coding_transcript_exon_variant 0.4
inhA 1674892 p.Asn231Asp missense_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518076 c.-39C>T upstream_gene_variant 1.0
folC 2747263 c.336C>A synonymous_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474415 p.His137Asn missense_variant 1.0
fbiB 3642772 p.Asp413Ala missense_variant 0.67
embC 4242425 p.Arg855Gly missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embC 4242761 p.Arg967Trp missense_variant 1.0
embC 4242803 p.Val981Leu missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0