TB-Profiler result

Run: ERR025887
Summary

Run ID: ERR025887

Sample name:

Date: 31-03-2023 08:19:02

Number of reads: 287228

Percentage reads mapped: 32.0

Strain: lineage1

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage1 Indo-Oceanic EAI RD239 0.06
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 6112 p.Met291Ile missense_variant 0.43
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9260 c.1959G>C synonymous_variant 0.5
gyrA 9304 p.Gly668Asp missense_variant 0.75
fgd1 490756 c.-27T>G upstream_gene_variant 0.67
mshA 575368 c.21T>C synonymous_variant 0.67
rpoC 763031 c.-339T>C upstream_gene_variant 1.0
rpoC 763884 p.Ala172Val missense_variant 0.8
rpoC 763886 c.517C>A synonymous_variant 0.8
rpoC 764995 c.1626C>G synonymous_variant 0.5
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776100 p.Thr794Ile missense_variant 0.33
fbiC 1302821 c.-110G>A upstream_gene_variant 0.29
Rv1258c 1406312 c.1029T>C synonymous_variant 0.57
embR 1416898 c.450C>T synonymous_variant 0.67
rrl 1474639 n.982G>A non_coding_transcript_exon_variant 0.4
inhA 1674162 c.-40C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154724 p.Arg463Leu missense_variant 0.67
kasA 2519048 p.Gly312Ser missense_variant 0.5
ahpC 2726051 c.-142G>A upstream_gene_variant 1.0
ahpC 2726338 p.Val49Gly missense_variant 0.38
fbiD 3339417 c.300A>G synonymous_variant 0.67
fprA 3474597 c.591C>A synonymous_variant 0.62
Rv3236c 3612009 p.Ala370Thr missense_variant 1.0
fbiB 3640557 c.-978T>C upstream_gene_variant 1.0
fbiB 3642772 p.Asp413Ala missense_variant 0.5
clpC1 4038287 c.2418C>T synonymous_variant 0.67
embC 4239763 c.-100C>T upstream_gene_variant 0.5
embC 4240671 p.Thr270Ile missense_variant 0.29
embA 4244420 c.1188G>C synonymous_variant 0.5
ubiA 4269387 p.Glu149Asp missense_variant 0.67
aftB 4269606 c.-770T>C upstream_gene_variant 0.5
whiB6 4338361 p.Arg54Gln missense_variant 1.0
gid 4407588 c.615A>G synonymous_variant 0.4
gid 4407873 c.330G>T synonymous_variant 1.0