TB-Profiler result

Run: ERR026641
Summary

Run ID: ERR026641

Sample name:

Date: 2024-10-04T10:41:08.157609

Number of reads: 1115492

Percentage reads mapped: 68.99

Median coverage: 14.0

Strain: lineage3

Spoligotype:

Drug-resistance: Sensitive

Download CSV Download TXT Download JSON
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family RDs Frequency
lineage3 East-African-Indian RD750 0.99
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations WHO confidence Comment
rifampicin
isoniazid
ethambutol
pyrazinamide
streptomycin
fluoroquinolones
moxifloxacin
ofloxacin
levofloxacin
ciprofloxacin
aminoglycosides
amikacin
capreomycin
kanamycin
cycloserine
ethionamide
clofazimine
para-aminosalicylic_acid
delamanid
bedaquiline
linezolid
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence Comment
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs Confidence
gyrA 7362 p.Glu21Gln missense_variant 1.0 levofloxacin Not assoc w R
moxifloxacin Not assoc w R
mshA 575980 c.633T>C synonymous_variant 1.0 isoniazid
ethionamide
rrs 1472494 n.649A>C non_coding_transcript_exon_variant 1.0 kanamycin
capreomycin
streptomycin
amikacin
tlyA 1917972 c.33A>G synonymous_variant 1.0 capreomycin Not assoc w R
PPE35 2169528 p.Leu362Pro missense_variant 1.0 pyrazinamide Uncertain significance
Rv1979c 2222158 p.Leu336Arg missense_variant 1.0 bedaquiline
clofazimine Uncertain significance
pncA 2289047 c.195C>T synonymous_variant 1.0 pyrazinamide Not assoc w R