TB-Profiler result

Run: ERR037495
Summary

Run ID: ERR037495

Sample name:

Date: 31-03-2023 08:34:10

Number of reads: 12850876

Percentage reads mapped: 99.53

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 762836 c.-534C>G upstream_gene_variant 0.31
atpE 1461019 c.-26C>A upstream_gene_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.22
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918623 c.684C>T synonymous_variant 1.0
PPE35 2169866 c.747G>C synonymous_variant 0.34
eis 2714366 p.Val323Leu missense_variant 0.28
eis 2715586 c.-254G>C upstream_gene_variant 0.42
Rv2752c 3064552 p.Arg547Pro missense_variant 0.2
Rv2752c 3064741 p.Gly484Ala missense_variant 0.24
thyA 3073806 c.666C>G synonymous_variant 0.24
fbiB 3642734 c.1200G>C synonymous_variant 0.21
fbiB 3642772 p.Asp413Ala missense_variant 0.18
clpC1 4038857 c.1848C>A synonymous_variant 0.19
clpC1 4039932 p.Gly258Val missense_variant 0.27
clpC1 4040830 c.-127_-126insC upstream_gene_variant 1.0
embC 4239842 c.-21C>A upstream_gene_variant 0.19
embC 4242425 p.Arg855Gly missense_variant 0.16
embC 4242476 p.Pro872Ala missense_variant 0.24
embC 4242822 p.Val987Gly missense_variant 0.34
ubiA 4269529 p.Ala102Gly missense_variant 0.16
ethA 4327672 c.-199G>A upstream_gene_variant 0.29
whiB6 4338595 c.-75delG upstream_gene_variant 1.0