TB-Profiler result

Run: ERR046817
Summary

Run ID: ERR046817

Sample name:

Date: 31-03-2023 08:52:46

Number of reads: 9615755

Percentage reads mapped: 99.96

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762836 c.-534C>G upstream_gene_variant 0.34
rpoC 767305 p.Tyr1312* stop_gained 0.19
mmpL5 777399 p.Thr361Arg missense_variant 0.15
Rv1258c 1406750 c.591C>A synonymous_variant 0.18
atpE 1461019 c.-26C>A upstream_gene_variant 0.23
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.14
rrl 1476408 n.2751G>C non_coding_transcript_exon_variant 0.16
inhA 1674892 p.Asn231Asp missense_variant 0.21
ndh 2102891 p.Phe51Ser missense_variant 0.28
PPE35 2167871 c.2742G>C synonymous_variant 0.19
PPE35 2169379 p.Phe412Val missense_variant 0.18
PPE35 2169866 c.747G>C synonymous_variant 0.34
eis 2714366 p.Val323Leu missense_variant 0.28
folC 2746186 c.1413G>C synonymous_variant 0.16
pepQ 2859381 c.1038C>G synonymous_variant 0.19
Rv2752c 3064741 p.Gly484Ala missense_variant 0.34
thyA 3073806 c.666C>G synonymous_variant 0.16
fprA 3475280 p.Val425Gly missense_variant 0.28
fbiB 3641955 p.Gly141Arg missense_variant 0.2
fbiB 3642772 p.Asp413Ala missense_variant 0.16
ddn 3987013 p.Gly57Ala missense_variant 0.2
clpC1 4038857 c.1848C>A synonymous_variant 0.19
clpC1 4039932 p.Gly258Val missense_variant 0.2
embC 4239842 c.-21C>A upstream_gene_variant 0.17
embC 4241056 c.1194C>G synonymous_variant 0.21
embC 4242476 p.Pro872Ala missense_variant 0.2
embC 4242822 p.Val987Gly missense_variant 0.28
embB 4248725 p.Ser738Ala missense_variant 0.2
ubiA 4269529 p.Ala102Gly missense_variant 0.22
ethA 4327672 c.-199G>A upstream_gene_variant 0.26