TB-Profiler result

Run: ERR046956
Summary

Run ID: ERR046956

Sample name:

Date: 31-03-2023 08:58:40

Number of reads: 4787899

Percentage reads mapped: 99.97

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
rpoC 762836 c.-534C>G upstream_gene_variant 0.37
mmpL5 777399 p.Thr361Arg missense_variant 0.22
rplC 800997 p.Asn63Lys missense_variant 0.27
rrs 1473369 n.1524A>G non_coding_transcript_exon_variant 0.15
rrl 1475332 n.1675G>T non_coding_transcript_exon_variant 0.11
rrl 1475363 n.1706C>A non_coding_transcript_exon_variant 0.25
ndh 2102891 p.Phe51Ser missense_variant 0.28
PPE35 2169866 c.747G>C synonymous_variant 0.38
eis 2714366 p.Val323Leu missense_variant 0.31
ribD 2987307 p.Ala157Pro missense_variant 0.18
Rv2752c 3064552 p.Arg547Pro missense_variant 0.19
Rv2752c 3064741 p.Gly484Ala missense_variant 0.23
fbiD 3339153 p.Leu12Phe missense_variant 0.15
fbiB 3641955 p.Gly141Arg missense_variant 0.15
fbiB 3642734 c.1200G>C synonymous_variant 0.19
fbiB 3642772 p.Asp413Ala missense_variant 0.13
clpC1 4038857 c.1848C>A synonymous_variant 0.17
clpC1 4039932 p.Gly258Val missense_variant 0.23
embC 4239842 c.-21C>A upstream_gene_variant 0.12
embC 4242822 p.Val987Gly missense_variant 0.35
embC 4242827 p.Leu989Val missense_variant 0.24
embB 4249618 c.3105C>G synonymous_variant 0.26
ubiA 4269529 p.Ala102Gly missense_variant 0.24
ethA 4327672 c.-199G>A upstream_gene_variant 0.2