TB-Profiler result

Run: ERR10465841

Summary

Run ID: ERR10465841

Sample name:

Date: 31-03-2023 10:19:55

Number of reads: 9523133

Percentage reads mapped: 99.55

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.29
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 776451 p.Gly677Asp missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303175 p.Leu82Trp missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154980 c.1132C>T synonymous_variant 1.0
PPE35 2170811 c.-199C>T upstream_gene_variant 1.0
Rv1979c 2221815 c.1350T>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.14
Rv3083 3449145 c.642G>A synonymous_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.28
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243667 c.435C>G synonymous_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.51
aftB 4268076 p.Met254Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0