TB-Profiler result

Run: ERR10610315
Summary

Run ID: ERR10610315

Sample name:

Date: 19-05-2023 11:14:03

Number of reads: 115171

Percentage reads mapped: 97.47

Strain: lineage4.1

Drug-resistance: Sensitive

Download CSV Download TXT Download PDF Download JSON
Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Rifampicin
Isoniazid
Ethambutol
Pyrazinamide
Streptomycin
Fluoroquinolones
Moxifloxacin
Ofloxacin
Levofloxacin
Ciprofloxacin
Aminoglycosides
Amikacin
Capreomycin
Kanamycin
Cycloserine
Ethionamide
Clofazimine
Para-aminosalicylic_acid
Delamanid
Bedaquiline
Linezolid
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.1 Euro-American T;X;H None 0.08
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8417 c.1116C>A synonymous_variant 0.5
gyrA 9304 p.Gly668Asp missense_variant 1.0
rpoB 762081 p.Gly759Cys missense_variant 0.22
rpoC 764855 p.Val496Met missense_variant 0.5
mmpL5 776708 p.Cys591* stop_gained 0.5
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrl 1474339 n.682C>A non_coding_transcript_exon_variant 0.33
rpsA 1834435 c.894G>A synonymous_variant 0.67
katG 2155263 c.849G>A synonymous_variant 0.67
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3641334 c.-201G>T upstream_gene_variant 1.0
alr 3841280 p.His47Gln missense_variant 1.0
rpoA 3877719 c.789C>T synonymous_variant 0.29
embC 4240138 c.276C>T synonymous_variant 0.67
embA 4245126 p.Val632Leu missense_variant 0.4
embB 4249408 c.2895G>A synonymous_variant 1.0