TB-Profiler result

Run: ERR10796607
Summary

Run ID: ERR10796607

Sample name:

Date: 31-03-2023 11:12:23

Number of reads: 638219

Percentage reads mapped: 100.0

Strain: lineage4.3.3

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.3.3 Euro-American (LAM) LAM;T RD115 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 8040 p.Gly247Ser missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
ccsA 620803 p.Phe305Ile missense_variant 0.12
rpoC 764732 p.Phe455Leu missense_variant 0.13
rpoC 764995 c.1626C>G synonymous_variant 1.0
rpoC 765809 p.Thr814Ala missense_variant 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 800981 p.Ser58Asn missense_variant 0.11
rplC 801119 p.Glu104Val missense_variant 0.11
embR 1416971 p.Ala126Asp missense_variant 0.18
atpE 1461077 c.35delG frameshift_variant 0.2
atpE 1461207 p.Ile55Phe missense_variant 0.18
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673412 c.-28G>A upstream_gene_variant 0.12
fabG1 1674028 p.Arg197Trp missense_variant 0.18
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289314 c.-73T>C upstream_gene_variant 0.22
kasA 2518320 p.Asp69Gly missense_variant 0.12
kasA 2518919 p.Gly269Ser missense_variant 1.0
ribD 2987546 c.708C>T synonymous_variant 0.2
thyA 3073868 p.Thr202Ala missense_variant 1.0
thyA 3074160 c.311delC frameshift_variant 0.14
ald 3086788 c.-32T>C upstream_gene_variant 1.0
Rv3083 3449139 c.636A>T synonymous_variant 0.2
Rv3083 3449179 p.Ile226Leu missense_variant 0.2
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568791 c.-112G>A upstream_gene_variant 0.22
fbiB 3642428 c.894G>A synonymous_variant 0.18
alr 3840416 c.1005C>T synonymous_variant 0.17
ddn 3986695 c.-149G>A upstream_gene_variant 0.17
ddn 3987283 p.Val147Ala missense_variant 0.17
clpC1 4039421 c.1284C>T synonymous_variant 0.2
clpC1 4039519 p.Pro396Ser missense_variant 0.12
embC 4239710 c.-153C>T upstream_gene_variant 0.15
embC 4239897 p.Val12Ala missense_variant 0.22
embC 4242182 p.Ala774Ser missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4246045 p.Val938Gly missense_variant 0.11
embB 4247341 c.828C>T synonymous_variant 0.33
embB 4249593 p.Thr1027Met missense_variant 0.15
aftB 4268040 p.Leu266Pro missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407581 p.Gly208Arg missense_variant 0.15
gid 4408156 p.Leu16Arg missense_variant 1.0