TB-Profiler result

Run: ERR11043568

Summary

Run ID: ERR11043568

Sample name:

Date: 31-03-2023 11:36:54

Number of reads: 4206627

Percentage reads mapped: 99.8

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.22
mshA 576482 p.Val379Leu missense_variant 0.12
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.26
pepQ 2860159 p.Ala87Gly missense_variant 0.18
fbiD 3339734 p.Ala206Gly missense_variant 0.68
fbiD 3339744 c.627A>T synonymous_variant 0.23
rpoA 3878641 c.-134C>G upstream_gene_variant 0.42
clpC1 4040480 c.225T>C synonymous_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.43
whiB6 4338595 c.-75delG upstream_gene_variant 1.0