TB-Profiler result

Run: ERR11043836

Summary

Run ID: ERR11043836

Sample name:

Date: 31-03-2023 11:41:57

Number of reads: 321368

Percentage reads mapped: 99.5

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491591 p.Lys270Met missense_variant 1.0
mshA 575679 p.Asn111Ser missense_variant 1.0
rpoB 760115 c.309C>T synonymous_variant 1.0
rpoC 765150 p.Gly594Glu missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
embR 1417520 c.-173G>A upstream_gene_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673351 c.-89G>A upstream_gene_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2167704 p.Leu970Ser missense_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ahpC 2726182 c.-11T>C upstream_gene_variant 0.25
pepQ 2859886 p.Ala178Gly missense_variant 0.25
Rv2752c 3065054 p.Glu380Lys missense_variant 0.2
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fbiB 3640551 c.-984C>T upstream_gene_variant 0.5
clpC1 4040732 c.-28G>A upstream_gene_variant 0.17
embC 4240780 c.918T>C synonymous_variant 0.22
embC 4242803 p.Val981Leu missense_variant 1.0
embB 4247230 c.717G>A synonymous_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0