TB-Profiler result

Run: ERR11044962
Summary

Run ID: ERR11044962

Sample name:

Date: 31-03-2023 12:03:40

Number of reads: 2483880

Percentage reads mapped: 99.52

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576113 p.Arg256Trp missense_variant 0.25
mshA 576117 p.Ala257Val missense_variant 0.14
mshA 576456 p.Val370Gly missense_variant 0.25
mshA 576606 p.Ala420Gly missense_variant 0.25
rpoC 764298 c.931_932dupGG frameshift_variant 0.11
rpoC 766966 p.Glu1199Asp missense_variant 0.1
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.23
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303157 p.His76Pro missense_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.23
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154915 c.1197A>G synonymous_variant 1.0
PPE35 2170037 c.576C>G synonymous_variant 0.25
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3086788 c.-32T>C upstream_gene_variant 1.0
ald 3087333 p.Val172Met missense_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.4
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
fprA 3474212 p.Lys69Thr missense_variant 0.17
whiB7 3568433 p.Arg83Gly missense_variant 0.2
rpoA 3878641 c.-134C>G upstream_gene_variant 0.75
clpC1 4038951 p.Phe585Ser missense_variant 0.21
clpC1 4039702 p.Asp335His missense_variant 0.17
embC 4240409 p.Pro183Ala missense_variant 0.46
embA 4242643 c.-590C>T upstream_gene_variant 1.0
aftB 4268619 p.Val73Gly missense_variant 0.17
whiB6 4338200 p.Asp108His missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0