TB-Profiler result

Run: ERR11049133
Summary

Run ID: ERR11049133

Sample name:

Date: 31-03-2023 12:06:56

Number of reads: 4817515

Percentage reads mapped: 99.77

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.27
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2169402 p.Thr404Met missense_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.18
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pncA 2289327 c.-86C>A upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.38
rpoA 3878641 c.-134C>G upstream_gene_variant 0.29
embC 4240409 p.Pro183Ala missense_variant 0.13
embB 4246584 p.Arg24Pro missense_variant 0.28
whiB6 4338595 c.-75delG upstream_gene_variant 1.0