TB-Profiler result

Run: ERR11049199
Summary

Run ID: ERR11049199

Sample name:

Date: 31-03-2023 15:19:53

Number of reads: 3203619

Percentage reads mapped: 99.57

Strain: lineage4.6.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.2
mshA 576482 p.Val379Leu missense_variant 0.11
mshA 576717 p.Gly457Val missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.45
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.19
rpoA 3878555 c.-48G>A upstream_gene_variant 0.13
rpoA 3878559 c.-53_-52insC upstream_gene_variant 0.16
rpoA 3878601 c.-95delG upstream_gene_variant 0.7
rpoA 3878613 c.-113_-107delCAACCCA upstream_gene_variant 0.63
rpoA 3878641 c.-134C>G upstream_gene_variant 0.2
rpoA 3878654 c.-147A>G upstream_gene_variant 0.94
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>T upstream_gene_variant 1.0
embB 4246529 p.Ser6Arg missense_variant 0.21
embB 4246584 p.Arg24Pro missense_variant 0.5
whiB6 4338595 c.-75delG upstream_gene_variant 1.0