TB-Profiler result

Run: ERR11049519
Summary

Run ID: ERR11049519

Sample name:

Date: 01-04-2023 07:17:54

Number of reads: 3033620

Percentage reads mapped: 99.93

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.3
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.16
thyA 3074139 c.333G>A synonymous_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.58
fbiD 3339746 p.Ala210Gly missense_variant 0.2
whiB7 3568428 c.252A>G synonymous_variant 0.28
rpoA 3877722 c.786C>T synonymous_variant 1.0
rpoA 3878613 c.-106A>C upstream_gene_variant 0.38
rpoA 3878641 c.-134C>G upstream_gene_variant 0.12
embC 4240409 p.Pro183Ala missense_variant 0.15
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244237 c.1005C>T synonymous_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.3
embB 4246529 p.Ser6Gly missense_variant 0.22
whiB6 4338595 c.-75delG upstream_gene_variant 1.0