TB-Profiler result

Run: ERR11049735

Summary

Run ID: ERR11049735

Sample name:

Date: 01-04-2023 18:32:02

Number of reads: 4753584

Percentage reads mapped: 99.93

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.19
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.2
PPE35 2170219 p.Ala132Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.21
thyA 3074139 c.333G>A synonymous_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.61
whiB7 3568428 c.252A>G synonymous_variant 0.28
rpoA 3878613 c.-106A>C upstream_gene_variant 0.22
rpoA 3878618 c.-111A>C upstream_gene_variant 0.31
rpoA 3878637 c.-130G>C upstream_gene_variant 0.15
rpoA 3878641 c.-134C>G upstream_gene_variant 0.36
embC 4240409 p.Pro183Ala missense_variant 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246529 p.Ser6Arg missense_variant 0.32
embB 4246584 p.Arg24Pro missense_variant 0.33
whiB6 4338595 c.-75delG upstream_gene_variant 1.0