TB-Profiler result

Run: ERR11049747

Summary

Run ID: ERR11049747

Sample name:

Date: 01-04-2023 19:07:27

Number of reads: 4142411

Percentage reads mapped: 99.76

Strain: lineage4.9

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.18
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.17
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.4
tlyA 1917972 c.33A>G synonymous_variant 0.99
PPE35 2170065 p.Ala183Gly missense_variant 0.3
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.25
pepQ 2860159 p.Ala87Gly missense_variant 0.19
fbiD 3339734 p.Ala206Gly missense_variant 0.8
fbiD 3339746 p.Ala210Gly missense_variant 0.21
whiB7 3568425 c.255T>C synonymous_variant 0.26
whiB7 3568428 c.252A>G synonymous_variant 0.25
rpoA 3878597 c.-90G>C upstream_gene_variant 0.38
rpoA 3878600 c.-93G>C upstream_gene_variant 0.25
rpoA 3878613 c.-106A>C upstream_gene_variant 0.33
rpoA 3878641 c.-134C>G upstream_gene_variant 0.65
embC 4240409 p.Pro183Ala missense_variant 0.16
embB 4246584 p.Arg24Pro missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0