TB-Profiler result

Run: ERR11049897
Summary

Run ID: ERR11049897

Sample name:

Date: 02-04-2023 01:54:22

Number of reads: 2309200

Percentage reads mapped: 99.77

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.23
mshA 576113 p.Arg256Gly missense_variant 0.22
mshA 576613 c.1266A>C synonymous_variant 0.5
mshA 576616 c.1269G>C synonymous_variant 0.43
rpoC 764367 p.Gly333Ala missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.3
mmpL5 779112 c.-632G>A upstream_gene_variant 1.0
mmpS5 779686 c.-781G>A upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.39
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.53
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.35
pepQ 2860159 p.Ala87Gly missense_variant 0.36
Rv2752c 3064823 p.Val457Leu missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.33
fbiD 3339751 p.Ala212Pro missense_variant 0.33
fbiB 3642185 c.651G>T synonymous_variant 0.98
rpoA 3878641 c.-134C>G upstream_gene_variant 0.62
panD 4043924 p.Asp120His missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.2
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.35
embB 4247016 p.Ser168Trp missense_variant 0.21
embB 4248328 c.1815G>C synonymous_variant 0.29
whiB6 4338200 p.Asp108His missense_variant 0.2
whiB6 4338595 c.-75delG upstream_gene_variant 1.0