TB-Profiler result

Run: ERR11050038
Summary

Run ID: ERR11050038

Sample name:

Date: 02-04-2023 08:40:03

Number of reads: 2239156

Percentage reads mapped: 99.82

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 9647 c.2346C>G synonymous_variant 0.17
mshA 576108 p.Ala254Gly missense_variant 0.2
mshA 576442 p.Cys365Trp missense_variant 0.28
mshA 576456 p.Val370Gly missense_variant 0.19
mshA 576468 p.Val374Gly missense_variant 0.25
mshA 576613 c.1266A>C synonymous_variant 0.26
mshA 576616 c.1269G>C synonymous_variant 0.23
rpoC 764367 p.Gly333Ala missense_variant 0.14
mmpL5 777883 p.Gly200Arg missense_variant 0.19
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.32
kasA 2519071 p.Asp319Glu missense_variant 0.3
pepQ 2860159 p.Ala87Gly missense_variant 0.2
Rv2752c 3064823 p.Val457Leu missense_variant 0.14
fbiD 3339734 p.Ala206Gly missense_variant 0.67
rpoA 3878597 c.-90G>C upstream_gene_variant 0.67
rpoA 3878637 c.-130G>C upstream_gene_variant 0.4
rpoA 3878641 c.-134C>G upstream_gene_variant 0.67
embC 4240409 p.Pro183Ala missense_variant 0.35
embB 4246527 p.Ala5Gly missense_variant 0.31
embB 4247016 p.Ser168Trp missense_variant 0.29
embB 4247020 c.507C>G synonymous_variant 0.39
embB 4247028 p.Leu172Arg missense_variant 0.29
embB 4248328 c.1815G>C synonymous_variant 0.34