TB-Profiler result

Run: ERR11050593
Summary

Run ID: ERR11050593

Sample name:

Date: 03-04-2023 12:20:52

Number of reads: 2775890

Percentage reads mapped: 99.64

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5839 c.600C>T synonymous_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.22
mshA 576108 p.Ala254Gly missense_variant 0.26
mshA 576613 c.1266A>G synonymous_variant 0.33
mshA 576618 p.His424Pro missense_variant 0.33
rpoC 764367 p.Gly333Ala missense_variant 0.17
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.23
mmpL5 778225 p.Asp86His missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304904 c.1974G>A synonymous_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.31
fabG1 1673558 p.His40Pro missense_variant 0.14
tlyA 1917814 c.-126C>G upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.23
folC 2747053 c.546C>T synonymous_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.23
ribD 2986804 c.-35T>C upstream_gene_variant 1.0
Rv2752c 3064823 p.Val457Leu missense_variant 0.19
ald 3087816 p.Cys333Gly missense_variant 0.15
fbiD 3339734 p.Ala206Gly missense_variant 0.67
fbiD 3339746 p.Ala210Gly missense_variant 0.29
fbiD 3339749 p.Val211Gly missense_variant 0.33
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
Rv3083 3448500 c.-4A>G upstream_gene_variant 1.0
Rv3083 3448501 c.-3G>T upstream_gene_variant 1.0
fprA 3474368 p.Gly121Asp missense_variant 1.0
rpoA 3878591 c.-84C>G upstream_gene_variant 0.5
rpoA 3878641 c.-134C>G upstream_gene_variant 0.69
embC 4240409 p.Pro183Ala missense_variant 0.28
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.3
embB 4247016 p.Ser168Trp missense_variant 0.21
embB 4247020 c.507C>G synonymous_variant 0.3
embB 4248328 c.1815G>C synonymous_variant 0.23
whiB6 4338200 p.Asp108His missense_variant 0.15
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0