TB-Profiler result

Run: ERR11050662
Summary

Run ID: ERR11050662

Sample name:

Date: 03-04-2023 15:39:02

Number of reads: 3733329

Percentage reads mapped: 99.72

Strain: lineage4.5

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.5 Euro-American H;T RD122 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 7892 c.591G>A synonymous_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.17
mshA 576453 p.Val369Gly missense_variant 0.24
mshA 576489 p.Val381Gly missense_variant 0.24
ccsA 620029 c.139C>T synonymous_variant 1.0
rpoC 764367 p.Gly333Ala missense_variant 0.2
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.2
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.28
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918066 p.Ala43Pro missense_variant 0.17
PPE35 2170065 p.Ala183Gly missense_variant 0.27
PPE35 2170568 p.Ile15Met missense_variant 1.0
Rv1979c 2222057 p.Asp370Asn missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.2
eis 2714984 p.Ala117Thr missense_variant 0.98
pepQ 2860159 p.Ala87Gly missense_variant 0.2
fbiD 3339734 p.Ala206Gly missense_variant 0.5
fbiD 3339749 p.Val211Ala missense_variant 0.57
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568425 c.255T>C synonymous_variant 0.33
whiB7 3568428 c.252A>G synonymous_variant 0.29
fbiB 3641364 c.-171G>A upstream_gene_variant 1.0
rpoA 3878575 c.-68C>T upstream_gene_variant 1.0
rpoA 3878597 c.-90G>C upstream_gene_variant 0.39
rpoA 3878618 c.-111A>C upstream_gene_variant 0.4
rpoA 3878641 c.-134C>G upstream_gene_variant 0.75
clpC1 4038318 p.Pro796Leu missense_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.18
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.33
embB 4246584 p.Arg24Pro missense_variant 0.13
embB 4248328 c.1815G>C synonymous_variant 0.25
aftB 4268596 p.Tyr81His missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4408345 c.-143C>G upstream_gene_variant 1.0