TB-Profiler result

Run: ERR11050683

Summary

Run ID: ERR11050683

Sample name:

Date: 03-04-2023 16:36:06

Number of reads: 4203496

Percentage reads mapped: 99.52

Strain: lineage4

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575562 p.Met72Thr missense_variant 0.99
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918384 p.Asp149Asn missense_variant 1.0
katG 2154980 c.1132C>T synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.32
PPE35 2170811 c.-199C>T upstream_gene_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2860159 p.Ala87Gly missense_variant 0.22
ald 3087801 p.Gly328Ser missense_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.58
Rv3083 3449145 c.642G>A synonymous_variant 1.0
whiB7 3568428 c.252A>G synonymous_variant 0.29
rpoA 3878641 c.-134C>G upstream_gene_variant 0.26
embC 4240409 p.Pro183Ala missense_variant 0.16
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.27
embB 4248328 c.1815G>C synonymous_variant 0.15
embB 4249802 p.Gly1097Ser missense_variant 1.0
aftB 4268076 p.Met254Ala missense_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0