TB-Profiler result

Run: ERR11050789
Summary

Run ID: ERR11050789

Sample name:

Date: 03-04-2023 21:07:43

Number of reads: 2508012

Percentage reads mapped: 99.5

Strain: lineage4.6.2

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.6 Euro-American T;LAM None 1.0
lineage4.6.2 Euro-American T;LAM RD726 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
gyrA 9647 c.2346C>G synonymous_variant 0.2
mshA 576453 p.Val369Gly missense_variant 0.18
mshA 576468 p.Val374Gly missense_variant 0.5
mshA 576618 p.His424Pro missense_variant 0.22
rpoC 764367 p.Gly333Ala missense_variant 0.23
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777883 p.Gly200Arg missense_variant 0.31
mmpR5 778298 c.-692C>T upstream_gene_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1473551 n.-107T>C upstream_gene_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.27
tlyA 1917972 c.33A>G synonymous_variant 1.0
PPE35 2170065 p.Ala183Gly missense_variant 0.19
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519071 p.Asp319Glu missense_variant 0.44
pepQ 2860159 p.Ala87Gly missense_variant 0.2
Rv2752c 3065902 p.Arg97Gln missense_variant 1.0
ald 3087816 p.Cys333Gly missense_variant 0.14
fbiD 3339734 p.Ala206Gly missense_variant 0.29
fbiD 3339751 p.Ala212Pro missense_variant 0.5
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
rpoA 3878580 c.-73A>C upstream_gene_variant 0.23
rpoA 3878641 c.-134C>G upstream_gene_variant 0.5
rpoA 3878654 c.-147A>G upstream_gene_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.3
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4242883 c.-350C>T upstream_gene_variant 1.0
embB 4246527 p.Ala5Gly missense_variant 0.5
embB 4246584 p.Arg24Pro missense_variant 0.33
embB 4247016 p.Ser168Trp missense_variant 0.2
embB 4248328 c.1815G>C synonymous_variant 0.21
whiB6 4338200 p.Asp108His missense_variant 0.17
whiB6 4338595 c.-75delG upstream_gene_variant 1.0