TB-Profiler result

Run: ERR11067890
Summary

Run ID: ERR11067890

Sample name:

Date: 05-04-2023 13:56:33

Number of reads: 3366937

Percentage reads mapped: 99.94

Strain: lineage4.9

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.9 Euro-American (H37Rv-like) T1 None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrB 5193 c.-47G>C upstream_gene_variant 1.0
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576108 p.Ala254Gly missense_variant 0.24
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777777 p.Met235Arg missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1473049 n.1205dupA non_coding_transcript_exon_variant 1.0
inhA 1673505 c.-697A>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
rpoA 3878641 c.-134C>G upstream_gene_variant 0.21
embC 4240967 c.1106_1108dupACG disruptive_inframe_insertion 1.0
embC 4241268 p.Val469Gly missense_variant 1.0
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246584 p.Arg24Pro missense_variant 0.12
embB 4247024 p.Pro171Ala missense_variant 0.19
whiB6 4338595 c.-75delG upstream_gene_variant 1.0