TB-Profiler result

Run: ERR11068192
Summary

Run ID: ERR11068192

Sample name:

Date: 06-04-2023 02:22:10

Number of reads: 804096

Percentage reads mapped: 99.66

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
rpoB 760975 p.Met390Thr missense_variant 1.0
rpoC 764037 p.Trp223* stop_gained 0.13
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1303149 c.219C>G synonymous_variant 0.17
fbiC 1304522 p.Leu531Pro missense_variant 0.1
embR 1416436 p.Gln304His missense_variant 0.23
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 0.97
rrl 1475090 n.1433A>C non_coding_transcript_exon_variant 1.0
fabG1 1673553 p.Asp38Glu missense_variant 0.14
tlyA 1917972 c.33A>G synonymous_variant 1.0
ndh 2102817 p.Leu76Val missense_variant 0.21
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
pepQ 2859931 p.Leu163Gln missense_variant 0.18
pepQ 2860159 p.Ala87Gly missense_variant 0.22
Rv2752c 3065539 p.Val218Ala missense_variant 0.13
ald 3086767 c.-53A>C upstream_gene_variant 1.0
fbiD 3339734 p.Ala206Gly missense_variant 0.6
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
embC 4240409 p.Pro183Ala missense_variant 0.4
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4248328 c.1815G>C synonymous_variant 0.55
aftB 4267228 p.Val537Met missense_variant 0.11
aftB 4267715 c.1122G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0