TB-Profiler result

Run: ERR11068351
Summary

Run ID: ERR11068351

Sample name:

Date: 06-04-2023 09:20:52

Number of reads: 3642902

Percentage reads mapped: 99.8

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
fgd1 491315 p.Gly178Asp missense_variant 0.1
mshA 575424 p.Arg26His missense_variant 0.33
mshA 576108 p.Ala254Val missense_variant 0.11
ccsA 620032 p.Ala48Thr missense_variant 0.29
rpoB 762774 p.Arg990Gly missense_variant 0.11
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304190 c.1260G>C synonymous_variant 0.17
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
fabG1 1673162 c.-278T>C upstream_gene_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918070 p.Thr44Ile missense_variant 0.22
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
eis 2715570 c.-238C>T upstream_gene_variant 0.5
folC 2747672 c.-74G>A upstream_gene_variant 0.11
pepQ 2860148 p.Gly91Ser missense_variant 0.18
fbiD 3339068 c.-50G>A upstream_gene_variant 0.12
whiB7 3568428 c.252A>C synonymous_variant 0.4
Rv3236c 3612047 p.Ala357Val missense_variant 0.97
fbiB 3641815 p.Ile94Asn missense_variant 0.16
fbiB 3641922 p.Ala130Thr missense_variant 0.11
clpC1 4039858 p.Ile283Val missense_variant 0.86
embC 4240425 p.Arg188His missense_variant 0.13
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243748 c.516C>G synonymous_variant 0.25
embB 4246820 p.Pro103Thr missense_variant 1.0
aftB 4267676 c.1161G>A synonymous_variant 0.1
ethA 4326505 c.969C>G synonymous_variant 1.0
ethR 4328039 p.Arg164Pro missense_variant 0.4
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0