TB-Profiler result

Run: ERR11068488
Summary

Run ID: ERR11068488

Sample name:

Date: 06-04-2023 14:40:32

Number of reads: 3969253

Percentage reads mapped: 99.64

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
ccsA 619984 c.94C>T synonymous_variant 0.12
rpoB 760975 p.Met390Thr missense_variant 1.0
rpoC 763941 p.Ala191Val missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304197 p.Gly423Ser missense_variant 0.1
Rv1258c 1407050 c.291C>T synonymous_variant 0.2
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rrl 1475090 n.1433A>C non_coding_transcript_exon_variant 1.0
rrl 1475778 n.2121G>T non_coding_transcript_exon_variant 0.2
rrl 1475962 n.2305G>A non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918600 p.His221Tyr missense_variant 0.11
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519099 p.Ala329Thr missense_variant 0.17
folC 2746620 p.Arg327Trp missense_variant 0.17
pepQ 2860002 c.417G>A synonymous_variant 0.11
thyX 3067469 c.477C>T synonymous_variant 0.1
ald 3086767 c.-53A>C upstream_gene_variant 1.0
Rv3083 3448497 c.-7T>A upstream_gene_variant 1.0
clpC1 4040235 p.Gly157Ala missense_variant 0.3
embC 4242563 p.Ala901Thr missense_variant 0.12
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4244263 p.Leu344Arg missense_variant 0.11
embA 4244503 c.1275delG frameshift_variant 0.11
embB 4246536 p.Arg8His missense_variant 0.11
embB 4246590 p.Thr26Met missense_variant 0.11
embB 4247104 c.591G>A synonymous_variant 0.12
embB 4247890 c.1377C>T synonymous_variant 0.1
aftB 4267715 c.1122G>A synonymous_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0