TB-Profiler result

Run: ERR11068552
Summary

Run ID: ERR11068552

Sample name:

Date: 06-04-2023 17:11:03

Number of reads: 3911670

Percentage reads mapped: 99.6

Strain: lineage4.8

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 575431 c.84C>G synonymous_variant 0.5
mshA 576116 p.Ala257Pro missense_variant 0.27
mshA 576187 c.840C>A synonymous_variant 0.11
mshA 576226 c.879G>A synonymous_variant 0.17
ccsA 620168 p.Ala93Val missense_variant 0.11
rpoB 761656 p.Ala617Asp missense_variant 0.12
mmpL5 775639 p.Ile948Val missense_variant 1.0
mmpL5 777314 p.Trp389* stop_gained 0.29
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rplC 801245 p.Arg146Leu missense_variant 0.14
Rv1258c 1407151 p.Thr64Ala missense_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
rpsA 1834905 c.1364_1365insT frameshift_variant 0.2
tlyA 1917972 c.33A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2518522 p.Lys136Asn missense_variant 1.0
kasA 2518757 p.Ala215Thr missense_variant 0.2
kasA 2519034 p.His307Pro missense_variant 0.14
eis 2714957 p.Tyr126His missense_variant 0.22
folC 2746844 p.Ala252Val missense_variant 0.12
pepQ 2859617 p.Ala268Thr missense_variant 0.11
pepQ 2859623 p.Pro266Ser missense_variant 0.11
pepQ 2859891 c.528G>C synonymous_variant 0.29
pepQ 2860229 p.Ala64Thr missense_variant 0.14
ribD 2987278 p.Ala147Val missense_variant 0.15
ribD 2987330 c.492G>A synonymous_variant 0.14
ribD 2987381 c.543G>A synonymous_variant 0.11
fbiB 3642181 p.Val216Gly missense_variant 0.15
fbiB 3642370 p.Ala279Glu missense_variant 0.2
clpC1 4040621 c.84C>T synonymous_variant 1.0
embC 4241029 p.Trp389* stop_gained 0.17
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243544 c.312G>A synonymous_variant 0.12
embA 4244521 p.Ala430Val missense_variant 0.17
embB 4246277 c.-237G>A upstream_gene_variant 0.99
embB 4246675 c.162G>C synonymous_variant 0.12
embB 4247847 p.Gln445Leu missense_variant 0.17
embB 4247851 c.1338C>A synonymous_variant 0.2
ethA 4327296 p.Tyr60His missense_variant 0.99
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
gid 4407945 c.258C>T synonymous_variant 0.97
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0