TB-Profiler result

Run: ERR11068773
Summary

Run ID: ERR11068773

Sample name:

Date: 07-04-2023 01:19:19

Number of reads: 4167591

Percentage reads mapped: 99.42

Strain: lineage4

Drug-resistance: Sensitive

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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
gyrA 7585 p.Ser95Thr missense_variant 1.0
gyrA 9304 p.Gly668Asp missense_variant 1.0
fgd1 491270 p.Tyr163Cys missense_variant 1.0
mshA 575390 p.Gln15Lys missense_variant 0.11
mshA 576119 p.Ala258Pro missense_variant 0.29
rpoC 763969 c.600C>T synonymous_variant 0.22
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471786 n.-60T>G upstream_gene_variant 0.19
rrl 1474571 n.914G>A non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
katG 2154915 c.1197A>G synonymous_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
kasA 2519016 p.Ser301Leu missense_variant 0.11
kasA 2519131 c.1017G>C synonymous_variant 0.14
eis 2714926 p.Thr136Asn missense_variant 0.17
eis 2714939 p.Gly132Trp missense_variant 0.2
eis 2715035 p.Met100Val missense_variant 0.25
pepQ 2859593 p.Ala276Thr missense_variant 0.11
pepQ 2859944 p.Ala159Thr missense_variant 0.25
ribD 2987332 p.Cys165Tyr missense_variant 0.14
thyX 3067342 p.Glu202Lys missense_variant 0.15
thyX 3067935 p.Thr4Ile missense_variant 0.11
ald 3086788 c.-32T>C upstream_gene_variant 1.0
fprA 3473996 c.-11_-10insA upstream_gene_variant 1.0
whiB7 3568431 c.249C>G synonymous_variant 0.18
clpC1 4038164 c.2541G>C synonymous_variant 0.2
embC 4241202 p.Gly447Asp missense_variant 0.11
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embA 4243919 p.Arg229Ser missense_variant 0.2
ethR 4327999 p.Ala151Thr missense_variant 0.12
whiB6 4338595 c.-75delG upstream_gene_variant 1.0