TB-Profiler result

Run: ERR11068813

Summary

Run ID: ERR11068813

Sample name:

Date: 07-04-2023 02:47:54

Number of reads: 3762679

Percentage reads mapped: 99.64

Strain: lineage4.8

Drug-resistance: Sensitive


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Drug resistance: This table reports drug-resistance associated mutations found in known resistance genes
Drug Resistance Supporting mutations
Lineage Table: The lineage is inferred by analysing lineage specific SNPs
Lineage Family Main Spoligotype RDs Frequency
lineage4 Euro-American LAM;T;S;X;H None 1.0
lineage4.8 Euro-American (mainly T) T1;T2;T3;T5 RD219 1.0
Drug resistance-Associated Mutations: This table reports mutations found in candidate resistance genes which have been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction Drugs
Non-Associated Mutations: This table reports mutations found in candidate resistance genes which have not been associated with drug resistance
Gene Chromosome position Mutation Type Estimated fraction
gyrA 7362 p.Glu21Gln missense_variant 1.0
mshA 576107 p.Ala254Thr missense_variant 0.4
mmpL5 775639 p.Ile948Val missense_variant 1.0
rpsL 781395 c.-165T>C upstream_gene_variant 1.0
fbiC 1304204 p.Ala425Val missense_variant 0.1
rrs 1471659 n.-187C>T upstream_gene_variant 1.0
rrs 1471786 n.-60T>G upstream_gene_variant 0.16
rrl 1474001 n.344C>T non_coding_transcript_exon_variant 1.0
tlyA 1917972 c.33A>G synonymous_variant 1.0
tlyA 1918021 p.Gly28Ser missense_variant 0.11
PPE35 2168149 p.Pro822Ser missense_variant 1.0
Rv1979c 2223293 c.-129A>G upstream_gene_variant 1.0
ald 3087348 p.Gly177Cys missense_variant 0.11
fbiD 3339668 p.Gly184Asp missense_variant 0.2
Rv3083 3448322 c.-182G>A upstream_gene_variant 1.0
whiB7 3568431 c.249C>G synonymous_variant 0.23
alr 3841143 p.Thr93Ile missense_variant 0.14
embA 4242643 c.-590C>T upstream_gene_variant 1.0
embB 4246567 c.54G>T synonymous_variant 0.12
ethR 4328039 p.Arg164Pro missense_variant 0.11
whiB6 4338498 c.23delA frameshift_variant 1.0
whiB6 4338595 c.-75delG upstream_gene_variant 1.0
Rv3083 3448507 c.5_*1408del frameshift_variant&stop_lost&splice_region_variant 1.0